has role
protective antigen role
protective antigen
Clostridium botulinum protein
BoNT/C(Hc50)
YH, ZX
protein
Researchers constructed a replication-incompetent adenovirus encoding a synthesized codon-optimized gene for expression of the heavy chain C-fragment (H(C)50) of botulinum neurotoxin type C (BoNT/C). After a single dose of 2 x 10^7pfu adenoviral vectors in a mouse model, the animals were completely protected against intraperitoneal challenge with 100 x MLD(50) of active BoNT/C [PubMed: 17897756].
Protegen ID: 450; NCBI Protein GI: 217781; NCBI Protein Accession: BAA14235.1; NCBITaxon: 12336