has role
protective antigen role
protective antigen
Influenza virus protein
NP from Influenza A virus H3N2
YH, ZX
Protegen ID: 515; NCBI Protein GI: 3722159; NCBITaxon: 41857
protein
BALB/c mice were immunized intranasally with an adjuvant (cholera toxin B subunit containing 0.2% of the whole toxin)-combined with A or B virus recombinant NP. The NP-immune mice, when challenged intranasally with a sublethal dose of the virus 3 wk after immunization, had accelerated virus clearance from the nasal site in both an influenza type-specific and a nonspecific manner, as shown by the protection from high morbidity from the second day after challenge [PubMed: 8621928].