has role
protective antigen role
protective antigen
Influenza virus protein
HA from Influenza A virus (A/WSN/1933(H1N1))
protein
Protegen ID: 518; NCBI Protein GI: 324200; NCBITaxon: 382835
YH, ZX
A nonpathogenic vector of the cytoplasmic domain of the VSV G protein and expressing influenza virus HA (derived from Influenza A virus (A/WSN/1933(H1N1))) provides complete protection from lethal influenza virus challenge after intranasal administration. A second vector with VSV G deleted and expressing HA (DeltaG-HA) is also protective and nonpathogenic and has the advantage of not inducing neutralizing antibodies to the vector itself [PubMed: 10196265].