has role
in taxon
Sarcocystis neurona merozoite
protective antigen role
protective antigen
Sarcocystis neurona protein
SAG1 from Sarcocystis neurona
YH, ZX
protein
Protegen ID: 672; NCBI Protein GI: 295682690; NCBITaxon: 42890
Horses were vaccinated with adjuvanted recombinant SnSAG1 (rSnSAG1)and 5 control (sham vaccinated) horses were vaccinated with adjuvant only. The effect of vaccination with rSnSAG1 on in vivo infection by S. neurona was evaluated by challenging all the horses with S. neurona merozoites. The study showed that vaccination with rSnSAG-1 produced antibodies in horses that neutralized merozoites when tested by in vitro culture and significantly reduced clinical signs demonstrated by in vivo challenge [PubMed: 19794889].