has role
in taxon
Trypanosoma brucei trypomastigote
protective antigen role
protective antigen
Trypanosoma brucei protein
TSA from Trypanosoma brucei
Protegen ID: 807; NCBI Protein GI: 62175539; NCBITaxon: 5691
YH, ZX
BALB-c mice immunized intramuscularly with a single dose (100 microg) of a plasmid DNA encoding the 5'-terminal region of the trans-sialidase (nTSA) gene of T. brucei brucei are able to produce IgG antibodies that bind to the bloodstream form of T. brucei-protein extract and recognize the recombinant nTSA protein, expressed in Escherichia coli. Furthermore, this DNA vaccination process was able to protect 60% of mice submitted to a challenge assay with the infective form of T. brucei brucei parasites [PubMed: 19582478].
protein