Term IRI Term label Parent term IRI Parent term label Alternative term Definition http://purl.obolibrary.org/obo/IEV_0000142 Growth http://purl.obolibrary.org/obo/IEV_0000082 Organism event The increase in size or mass of an entire organism, a part of an organism or a cell. http://purl.obolibrary.org/obo/IEV_0003875 T cell differentiation http://purl.obolibrary.org/obo/IEV_0001314 Lymphocyte differentiation The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. http://purl.obolibrary.org/obo/IEV_0000115 ERK cascade http://purl.obolibrary.org/obo/IEV_0000445 MAPKKK cascade A cascade of protein kinase activities, culminating in the phosphorylation and activation of either the ERK1 or ERK2 kinases, which in turn are a subfamily of mitogen-activated protein (MAP) kinases. Note that this MAPKKK cascade is commonly referred to as the ERK pathway in the literature, but involves only ERK1 or ERK2, not other ERK kinases. http://purl.obolibrary.org/obo/IEV_0001269 Positive regulation of IKK-NF-kappaB signaling http://purl.obolibrary.org/obo/IEV_0001267 Regulation of IKK-NF-kappaB signaling Any process that activates or increases the frequency, rate or extent of an I-kappaB kinase/NF-kappaB induced cascade. http://purl.obolibrary.org/obo/IEV_0003747 Reproductive process in a multicellular organism http://purl.obolibrary.org/obo/IEV_0001327 Multicellular organismal process The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs. http://purl.obolibrary.org/obo/IEV_0001551 Atrazine degradation http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide. http://purl.obolibrary.org/obo/IEV_0000704 Negative regulation of Ras mediated signaling http://purl.obolibrary.org/obo/IEV_0000683 Negative regulation of small GTPase mediated signaling Any process that stops, prevents or reduces the rate, frequency or extent of Ras protein signal transduction. http://purl.obolibrary.org/obo/IEV_0001445 C21-Steroid hormone metabolism http://purl.obolibrary.org/obo/IEV_0001446 Steroid hormone biosynthesis The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones. http://purl.obolibrary.org/obo/IEV_0001515 Retinol metabolism http://purl.obolibrary.org/obo/IEV_0001553 Lipid Metabolism The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A. http://purl.obolibrary.org/obo/IEV_0001403 Regulation of cell cycle process http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. http://purl.obolibrary.org/obo/IEV_0000396 Lignin biosynthesis http://purl.obolibrary.org/obo/IEV_0001557 Amino acid derivative metabolism The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers. http://purl.obolibrary.org/obo/IEV_0001329 Seed development http://purl.obolibrary.org/obo/IEV_0001327 Multicellular organismal process Processes aimed at the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves. http://purl.obolibrary.org/obo/IEV_0000230 Phosphorylation of c-Jun by JNK_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003403 Phosphorylation of transcriptional regulator by JNK_p in inner space of nucleus The process of introducing a phosphoric group into a JUN protein. http://purl.obolibrary.org/obo/IEV_0001322 Organelle organization http://purl.obolibrary.org/obo/IEV_0001320 Cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. http://purl.obolibrary.org/obo/IEV_0001547 Fluorene degradation http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism The chemical reactions and pathways resulting in the breakdown of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents. http://purl.obolibrary.org/obo/IEV_0001550 Benzoate degradation via hydroxylation http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism The chemical reactions and pathways resulting in the breakdown of benzoate, by its hydroxylation to cis-1,2-dihydroxybenzoate followed by dehydrogenation to catechol. http://purl.obolibrary.org/obo/IEV_0001260 Rho mediated signaling http://purl.obolibrary.org/obo/IEV_0000676 Small GTPase mediated signaling A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state. http://purl.obolibrary.org/obo/IEV_0001447 Glycerolipid metabolism http://purl.obolibrary.org/obo/IEV_0001553 Lipid Metabolism The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis. http://purl.obolibrary.org/obo/IEV_0000447 Anatomical structure morphogenesis http://purl.obolibrary.org/obo/IEV_0000083 Development The process by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. http://purl.obolibrary.org/obo/IEV_0001497 Glycosphingolipid biosynthesis-globoseries http://purl.obolibrary.org/obo/IEV_0001494 Sphingolipid metabolism The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1,3)-Gal-alpha(1,4)Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes. http://purl.obolibrary.org/obo/IEV_0003394 asynthetic interaction http://purl.obolibrary.org/obo/IEV_0002682 genetic interaction The phenotype resulting from genetic perturbation of A alone, B alone and AB combined have the same effect on the WT background. http://purl.obolibrary.org/obo/IEV_0001420 Starch and sucrose metabolism http://purl.obolibrary.org/obo/IEV_0001422 Carbohydrate Metabolism Starch metabolism: The chemical reactions and pathways involving starch, the most important reserve polysaccharide in plants. It is a glucan consisting of two components, amylose and amylopectin, which are both glucose homopolymers. Starch is synthesized as a temporary storage form of carbon and can be catabolized to produce sucrose. Sucrose metabolism: The chemical reactions and pathways involving sucrose, the disaccharide fructofuranosyl-glucopyranoside. http://purl.obolibrary.org/obo/IEV_0001283 Binding of Ig alpha and Syk in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol he B-cell linker protein (BLNK) binds to tyrosine 204 of Ig alpha. http://purl.obolibrary.org/obo/IEV_0001374 Regulation of T cell receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell. http://purl.obolibrary.org/obo/IEV_0001350 Regulation of EGF signaling pathway http://purl.obolibrary.org/obo/IEV_0000834 Regulation of RTK signaling pathway Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity. http://purl.obolibrary.org/obo/IEV_0001199 Actomyosin structure organization and biogenesis http://purl.obolibrary.org/obo/IEV_0000092 Cytoskeleton organization The assembly and arrangement of cytoskeletal structures containing both actin and myosin. The myosin may be organized into filaments. http://purl.obolibrary.org/obo/IEV_0000638 Actin filament depolymerization http://purl.obolibrary.org/obo/IEV_0000637 Actin polymerization and/or depolymerization Disassembly of actin filaments by the removal of actin monomers from a filament. http://purl.obolibrary.org/obo/IEV_0001543 Styrene degradation http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism The chemical reactions and pathways resulting in the breakdown of styrene, an aromatic hydrocarbon liquid used in the manufacture of polystyrene. http://purl.obolibrary.org/obo/IEV_0001498 Glycosphingolipid biosynthesis-ganglioseries http://purl.obolibrary.org/obo/IEV_0001494 Sphingolipid metabolism The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues. http://purl.obolibrary.org/obo/IEV_0002537 Mesoderm development http://purl.obolibrary.org/obo/IEV_0003796 Tissue development The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue. http://purl.obolibrary.org/obo/IEV_0000454 IGF signaling pathway http://purl.obolibrary.org/obo/IEV_0003684 Insulin receptor family signaling pathway The series of molecular signals generated as a consequence of the insulin-like growth factor receptor binding to one of its physiological ligands. http://purl.obolibrary.org/obo/IEV_0000742 Visual perception http://purl.obolibrary.org/obo/IEV_0000744 Neurological system process The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image. http://purl.obolibrary.org/obo/IEV_0001472 D-Alanine metabolism http://purl.obolibrary.org/obo/IEV_0001410 Alanine and aspartate metabolism The chemical reactions and pathways involving D-alanine, the dextrorotatory isomer of the amino acid alanine. http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0001886 Molecular interaction The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, within or between cells. http://purl.obolibrary.org/obo/IEV_0000074 Seed dormancy http://purl.obolibrary.org/obo/IEV_0000072 Dormancy The process by which a dormant state is induced and maintained in a seed. Dormancy is characterized by a suspension of physiological activity that can be reactivated once dormancy is broken. http://purl.obolibrary.org/obo/IEV_0003662 Muscle system process http://purl.obolibrary.org/obo/IEV_0001327 Multicellular organismal process A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers. http://purl.obolibrary.org/obo/IEV_0001333 Response to biotic stimulus http://purl.obolibrary.org/obo/IEV_0001332 Response to stimulus A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the perception of a biotic stimulus. http://purl.obolibrary.org/obo/IEV_0000079 Cytokinesis http://purl.obolibrary.org/obo/IEV_0003382 Cell division A cellular process resulting in the division of the cytoplasm of a cell and its separation into two daughter cells. Cytokinesis usually occurs after growth, replication, and segregation of cellular components. http://purl.obolibrary.org/obo/IEV_0000501 Negative regulation of insulin signaling pathway http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway Any process that stops, prevents or reduces the frequency, rate or extent of insulin receptor signaling. http://purl.obolibrary.org/obo/IEV_0001548 Carbazole degradation http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism The chemical reactions and pathways resulting in the breakdown of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen. http://purl.obolibrary.org/obo/IEV_0001104 DNA damage http://purl.obolibrary.org/obo/IEV_0000071 Molecular event Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA REPLICATION. These deviations may be caused by physical or chemical agents and occur by natural or unnatural, introduced circumstances. They include the introduction of illegitimate bases during replication or by deamination or other modification of bases; the loss of a base from the DNA backbone leaving an abasic site; single-strand breaks; double strand breaks; and intrastrand ( PYRIMIDINE DIMERS) or interstrand crosslinking. Damage can often be repaired ( DNA REPAIR). If the damage is extensive, it can induce APOPTOSIS. http://purl.obolibrary.org/obo/IEV_0003812 Amino acid and derivative metabolism http://purl.obolibrary.org/obo/IEV_0000818 Metabolic pathway The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents, and compounds derived from amino acids, as carried out by individual cells. http://purl.obolibrary.org/obo/IEV_0003396 epistatic interaction http://purl.obolibrary.org/obo/IEV_0002682 genetic interaction The phenotype resulting from genetic perturbation of A and B have different effects (in terms of direction or magnitude) on the wild-type background and the double mutant has the same phenotype as either A or B (for example, A < WT < B = AB). http://purl.obolibrary.org/obo/IEV_0001455 Valine, leucine and isoleucine biosynthesis http://purl.obolibrary.org/obo/IEV_0001556 Amino Acid Metabolism Valine biosynthesis: The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid. Leucine biosynthesis: The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid. Isoleucine biosynthesis: The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid. http://purl.obolibrary.org/obo/IEV_0000226 JNK cascade http://purl.obolibrary.org/obo/IEV_0000445 MAPKKK cascade A cascade of protein kinase activities, culminating in the phosphorylation and activation of a JUN kinase, a member of a subfamily of mitogen-activated protein (MAP) kinases that is activated primarily by cytokines and exposure to environmental stress. http://purl.obolibrary.org/obo/IEV_0001343 Binding of IL-2 and IL-2 receptor and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0000045 Binding of cytokine and cytokine receptors and conformational change of receptors in plasma membrane Combining with interleukin-2 to initiate a change in cell activity. http://purl.obolibrary.org/obo/IEV_0001431 Oxidative phosphorylation http://purl.obolibrary.org/obo/IEV_0001552 Energy Metabolism The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis. http://purl.obolibrary.org/obo/IEV_0000098 Immune response http://purl.obolibrary.org/obo/IEV_0001332 Response to stimulus Any process involved in the immunological reaction of an organism to an immunogenic stimulus. http://purl.obolibrary.org/obo/IEV_0001106 G1 phase http://purl.obolibrary.org/obo/IEV_0000366 Cell cycle process Progression through G1 phase, one of two 'gap' phases in the cell cycle; G1 is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis. http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway http://purl.obolibrary.org/obo/IEV_0000001 Pathway The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms. http://purl.obolibrary.org/obo/IEV_0000779 PKC activation signaling http://purl.obolibrary.org/obo/IEV_0001302 Calcium ion dependent protein activation signaling The series of molecular signals that results in the upregulation of protein kinase C activity in response to the signal. http://purl.obolibrary.org/obo/IEV_0000895 R-Smad degradation signaling http://purl.obolibrary.org/obo/IEV_0000122 Proteasome mediated protein degradation signaling The chemical reactions and pathways resulting in the breakdown of SMAD signaling proteins by ubiquitination and targeting to the proteasome. http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002721 enzymatic reaction EC:1 catalyzed process http://purl.obolibrary.org/obo/IEV_0003813 Amide metabolism http://purl.obolibrary.org/obo/IEV_0000818 Metabolic pathway The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells. http://purl.obolibrary.org/obo/IEV_0001739 Beta catenin degradation signaling http://purl.obolibrary.org/obo/IEV_0001676 Negative regulation of Wnt signaling pathway The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome. http://purl.obolibrary.org/obo/IEV_0001822 Vasoconstriction http://purl.obolibrary.org/obo/IEV_0001821 Regulation of blood vessel size A decrease in the diameter of blood vessels, especially arteries, usually causing an increase in blood pressure. http://purl.obolibrary.org/obo/IEV_0001823 Muscle cell differentiation http://purl.obolibrary.org/obo/IEV_0000002 Cell differentiation The process whereby a relatively unspecialized cell acquires specialized features of a muscle cell. http://purl.obolibrary.org/obo/IEV_0000575 Post-embryonic morphogenesis http://purl.obolibrary.org/obo/IEV_0000447 Anatomical structure morphogenesis The process, occurring after embryonic development, by which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. http://purl.obolibrary.org/obo/IEV_0001441 Fatty acid metabolism http://purl.obolibrary.org/obo/IEV_0001553 Lipid Metabolism The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis. http://purl.obolibrary.org/obo/IEV_0003905 Lung development http://purl.obolibrary.org/obo/IEV_0002712 Organ development The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. http://purl.obolibrary.org/obo/IEV_0000052 Autophosphorylation of Jak in cytosol http://purl.obolibrary.org/obo/IEV_0000481 Autophosphorylation in cytosol The process of introducing a phosphoric group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it. http://purl.obolibrary.org/obo/IEV_0000866 NGF receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0000830 RTK signaling pathway The series of molecular signals generated as a consequence of the nerve growth factor receptor binding to one of its physiological ligands. http://purl.obolibrary.org/obo/IEV_0001549 Benzoate degradation via CoA ligation http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism The chemical reactions and pathways resulting in the breakdown of benzoate, by its ligation to Coenzyme A to form benzoyl-CoA, which is then broken by an aerobic or anaerobic pathway. http://purl.obolibrary.org/obo/IEV_0001433 Photosynthesis http://purl.obolibrary.org/obo/IEV_0001552 Energy Metabolism The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds. http://purl.obolibrary.org/obo/IEV_0003919 Artery morphogenesis http://purl.obolibrary.org/obo/IEV_0003918 Blood vessel morphogenesis The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs. http://purl.obolibrary.org/obo/IEV_0000709 ADP ribosylation http://purl.obolibrary.org/obo/IEV_0000913 Transference Reaction that can affect Arg, Cys, Glu, Arg and Asn residues. http://purl.obolibrary.org/obo/IEV_0003878 Cell activation http://purl.obolibrary.org/obo/IEV_0000069 Cellular event A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/IEV_0000208 IKK-NF-kappaB cascade http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway A series of reactions initiated by the activation of the transcription factor NF-kappaB. NF-kappaB is sequestered by the inhibitor I-kappaB, and is released when I-kappaB is phosphorylated by activated I-kappaB kinase. http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0000009 Translocation The directed movement of substances into the nucleus. http://purl.obolibrary.org/obo/IEV_0000019 Nuclear export http://purl.obolibrary.org/obo/IEV_0000009 Translocation The directed movement of substances out of the nucleus. http://purl.obolibrary.org/obo/IEV_0000027 Wnt signaling pathway http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell. http://purl.obolibrary.org/obo/IEV_0000078 Cell cycle arrest http://purl.obolibrary.org/obo/IEV_0000366 Cell cycle process The process by which the cell cycle is halted during one of the normal phases (G1, S, G2, M). http://purl.obolibrary.org/obo/IEV_0000084 Adipocyte differentiation http://purl.obolibrary.org/obo/IEV_0000002 Cell differentiation The process whereby a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat. http://purl.obolibrary.org/obo/IEV_0000086 Osteoblast differentiation http://purl.obolibrary.org/obo/IEV_0000002 Cell differentiation Differentiation of the osteoblast; which is the mesodermal cell that gives rise to bone. http://purl.obolibrary.org/obo/IEV_0000091 Cell growth http://purl.obolibrary.org/obo/IEV_0000069 Cellular event The process by which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. http://purl.obolibrary.org/obo/IEV_0000092 Cytoskeleton organization http://purl.obolibrary.org/obo/IEV_0001322 Organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/IEV_0000093 Lamellipodium biogenesis http://purl.obolibrary.org/obo/IEV_0001320 Cellular component organization Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell. http://purl.obolibrary.org/obo/IEV_0000102 M phase http://purl.obolibrary.org/obo/IEV_0000366 Cell cycle process A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the cell cycle comprising nuclear division. http://purl.obolibrary.org/obo/IEV_0000105 Cell adhesion http://purl.obolibrary.org/obo/IEV_0000069 Cellular event The attachment of a cell, either to another cell or to the extracellular matrix, via cell adhesion molecules. http://purl.obolibrary.org/obo/IEV_0000107 B cell receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell. http://purl.obolibrary.org/obo/IEV_0000122 Proteasome mediated protein degradation signaling http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. http://purl.obolibrary.org/obo/IEV_0000125 Glutamate receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway The series of molecular signals generated as a consequence of glutamate binding to a cell surface receptor. http://purl.obolibrary.org/obo/IEV_0000150 Negative regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway Any process that stops, prevents or reduces the frequency, rate or extent of the JAK-STAT signaling pathway activity. http://purl.obolibrary.org/obo/IEV_0000219 Translation http://purl.obolibrary.org/obo/IEV_0001886 Molecular interaction The chemical reactions and pathways resulting in the formation of a protein. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein. http://purl.obolibrary.org/obo/IEV_0000222 Myristoylation http://purl.obolibrary.org/obo/IEV_0002681 lipid addition Reaction that can affect K or G residues. http://purl.obolibrary.org/obo/IEV_0000227 Phosphorylation of MKK4/7 by MAPKKK in cytosol http://purl.obolibrary.org/obo/IEV_0000474 Phosphorylation of MAPKK by MAPKKK in cytosol The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity in response to phosphorylation by a member of the JUN kinase kinase kinase (JNKKK) family, or another upstream kinase. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress. http://purl.obolibrary.org/obo/IEV_0000366 Cell cycle process http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. http://purl.obolibrary.org/obo/IEV_0000437 Hydroxylation http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction Irreversible reaction that can affect K,P,Y or R residues. http://purl.obolibrary.org/obo/IEV_0000480 Nuclear import of MAPK (through MAPKKK cascade) http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import The directed movement of a MAP kinase to the nucleus upon activation. http://purl.obolibrary.org/obo/IEV_0000551 Positive regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity. http://purl.obolibrary.org/obo/IEV_0000639 Actin filament polymerization http://purl.obolibrary.org/obo/IEV_0000637 Actin polymerization and/or depolymerization Assembly of actin filaments by the addition of actin monomers to a filament. http://purl.obolibrary.org/obo/IEV_0000650 Phosphorylation of myosin phosphatase by p160ROCK in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol Inactivation of myosin phosphatase http://purl.obolibrary.org/obo/IEV_0000676 Small GTPase mediated signaling http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals. http://purl.obolibrary.org/obo/IEV_0000681 Regulation of small GTPase mediated signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction. http://purl.obolibrary.org/obo/IEV_0000687 Hydrolysis of ATP to cAMP by adenylate cyclase in cytosol http://purl.obolibrary.org/obo/IEV_0000685 Hydrolysis in cytosol The formation from simpler components of cyclic AMP, adenosine 3',5'-phosphate. http://purl.obolibrary.org/obo/IEV_0000745 Neurotransmitter secretion http://purl.obolibrary.org/obo/IEV_0003806 Neurotransmitter transport The regulated release of neurotransmitter into the synaptic cleft. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin. http://purl.obolibrary.org/obo/IEV_0000782 Phosphorylation of IKK complex by MEKK3 in cytosol http://purl.obolibrary.org/obo/IEV_0000250 Phosphorylation of IKK complex by MAPKKK in cytosol TNFR1 signaling http://purl.obolibrary.org/obo/IEV_0000819 Phosphorylation of Elk-1 by ERK_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003869 Phosphorylation of ets domain transcription factor by ERK_p in inner space of nucleus PDGF signaling http://purl.obolibrary.org/obo/IEV_0000829 Binding of Ral-GTP and RalBP1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol Activation of RalBP1 by Ral-GTP http://purl.obolibrary.org/obo/IEV_0000873 Regulation of TGF beta signaling pathway http://purl.obolibrary.org/obo/IEV_0000876 Regulation of TGF beta super family signaling pathway (through p38 cascade) Any process that modulates the frequency, rate or extent of activity of any TGFbeta receptor signaling pathway. http://purl.obolibrary.org/obo/IEV_0000875 Positive regulation of TGF beta signaling pathway http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway Any process that activates or increases the rate, frequency or extent of TGFbeta receptor signaling pathway activity. http://purl.obolibrary.org/obo/IEV_0000883 Negative regulation of BMP signaling pathway http://purl.obolibrary.org/obo/IEV_0000880 Negative regulation of TGF beta super family signaling pathway Any process that stops, prevents or reduces the rate, frequency or extent of BMP signaling pathway activity. http://purl.obolibrary.org/obo/IEV_0000884 Positive regulation of BMP signaling pathway http://purl.obolibrary.org/obo/IEV_0000882 Regulation of BMP signaling pathway Any process that activates or increases the rate, frequency or extent of BMP signaling pathway activity. http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0000019 Nuclear export The directed movement of mRNA from the nucleus to the cytoplasm. http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002721 enzymatic reaction EC:2 catalyzed process http://purl.obolibrary.org/obo/IEV_0000920 Geranylgeranylation http://purl.obolibrary.org/obo/IEV_0000921 Isoprenylation Reversible reaction that can affect C residue. http://purl.obolibrary.org/obo/IEV_0000987 Cytochrome c mediated signaling http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway Upregulation of the activity of a caspase, any of a group of cysteine proteases involved in apoptosis, mediated by cytochrome c. http://purl.obolibrary.org/obo/IEV_0001084 Cyclin D degradation signaling http://purl.obolibrary.org/obo/IEV_0001096 Negative regulation of S phase The chemical reactions and pathways resulting in the breakdown of cyclins, proteins whose levels in a cell varies markedly during the cell cycle, and which play key roles in regulating cell cycle phase transitions. http://purl.obolibrary.org/obo/IEV_0001088 Binding of p16 and Cdk4/6 in cytosol http://purl.obolibrary.org/obo/IEV_0001087 Binding of INK4 family and Cdk4/6 in cytosol Interacts strongly with CDK4 and CDK6. Inhibits their ability to interact with cyclins D. Could act as a negative regulator of the proliferation of normal cells. http://purl.obolibrary.org/obo/IEV_0001093 Binding of p18 and Cdk4/6 in cytosol http://purl.obolibrary.org/obo/IEV_0001087 Binding of INK4 family and Cdk4/6 in cytosol Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB. http://purl.obolibrary.org/obo/IEV_0001134 Dephosphorylation Cdc2 by Cdc25C in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol Functions as a dosage-dependent inducer in mitotic control. It is a tyrosine protein phosphatase required for progression of the cell cycle. It directly dephosphorylates CDC2 and activate its kinase activity. CATALYTIC ACTIVITY: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate. http://purl.obolibrary.org/obo/IEV_0001135 Phosphorylation of Cdc2 by Wee1 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol May act as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDC2 before the onset of mitosis. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation. Specifically phosphorylates and inactivates cyclin B1-complexed CDC2 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDC2 occurs exclusively on Tyr-15 and phosphorylation of monomeric CDC2 does not occur. CATALYTIC ACTIVITY: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. http://purl.obolibrary.org/obo/IEV_0001136 Negative regulation of G2-M-phase transition http://purl.obolibrary.org/obo/IEV_0001404 Negative regulation of cell cycle process Any process that decreases the rate or extent of progression from G2 phase to M phase of the mitotic cell cycle. http://purl.obolibrary.org/obo/IEV_0001137 Regulation of G2-M-phase transition http://purl.obolibrary.org/obo/IEV_0001403 Regulation of cell cycle process Any process that modulates the rate or extent of progression from G2 phase to M phase of the mitotic cell cycle. http://purl.obolibrary.org/obo/IEV_0001138 Positive regulation of G2-M-phase transition http://purl.obolibrary.org/obo/IEV_0001405 Positive regulation of cell cycle process Any process that increases the rate or extent of progression from G2 phase to M phase of the mitotic cell cycle. http://purl.obolibrary.org/obo/IEV_0001169 Hydrolysis of Notch by ADAM in plasma membrane http://purl.obolibrary.org/obo/IEV_0000269 Hydrolysis in plasma membrane near the transmembrane domain http://purl.obolibrary.org/obo/IEV_0001178 Regulation of Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway Any process that modulates the frequency, rate or extent of the Notch signaling pathway. http://purl.obolibrary.org/obo/IEV_0001198 Complex formation of BCR complex and coreceptor in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane Signal transduction by the BCR and coreceptor complexes is initiated by the recruitment and activation of tyrosine kinases. Upon antigen binding, membrane immunoglobulin and the Ig alpha-Ig beta heterodimer translocate to the glycolipid and cholesterol-rich membrane microdomains (lipid rafts) wherein fatty-acid-modified Src family kinases are constitutively present. Similarly, coengagement of the BCR and CD21 with multimeric C3d(g) bound to antigen promotes CD19-CD21-CD81 partitioning to the rafts, functioning to augment and potentiate signal transduction. http://purl.obolibrary.org/obo/IEV_0001246 Cytosolic calcium ion concentration elevation http://purl.obolibrary.org/obo/IEV_0000771 Change in material concentration Any process that increases the concentration of calcium ions in the cytosol. http://purl.obolibrary.org/obo/IEV_0001254 Notch receptor processing http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway The series of successive proteolytic cleavage events that take place after a Notch receptor binds a ligand, and which lead to the release of the Notch Intracellular Domain (NICD), which is the active form of the receptor. http://purl.obolibrary.org/obo/IEV_0001274 Negative regulation of B cell receptor signaling http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway Any process that stops, prevents or reduces the rate, frequency or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell. http://purl.obolibrary.org/obo/IEV_0001279 Phosphorylation of Ig alpha:beta by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol The immunoglobulin (Ig) and Ig cytoplasmic tails are phosphorylated on the immunoreceptor tyrosine-based activation motif (ITAM) tyrosines by Src-family tyrosine kinases (SFTKs) and/or Syk. http://purl.obolibrary.org/obo/IEV_0001319 Cell communication http://purl.obolibrary.org/obo/IEV_0000069 Cellular event Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/IEV_0001320 Cellular component organization http://purl.obolibrary.org/obo/IEV_0000069 Cellular event A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. http://purl.obolibrary.org/obo/IEV_0001321 Cytoplasm organization http://purl.obolibrary.org/obo/IEV_0001320 Cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. http://purl.obolibrary.org/obo/IEV_0001323 Actin cytoskeleton organization and biogenesis http://purl.obolibrary.org/obo/IEV_0000092 Cytoskeleton organization The assembly and arrangement of cytoskeletal structures comprising actin filaments and their associated proteins. http://purl.obolibrary.org/obo/IEV_0001336 Response to external stimulus http://purl.obolibrary.org/obo/IEV_0001332 Response to stimulus A change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the perception of an external stimulus. http://purl.obolibrary.org/obo/IEV_0001344 Binding of IL3 and IL3 receptor and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0000045 Binding of cytokine and cytokine receptors and conformational change of receptors in plasma membrane Combining with interleukin-3 to initiate a change in cell activity. http://purl.obolibrary.org/obo/IEV_0001345 Binding of IL4 and IL4 receptor and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0000045 Binding of cytokine and cytokine receptors and conformational change of receptors in plasma membrane Combining with interleukin-4 to initiate a change in cell activity. http://purl.obolibrary.org/obo/IEV_0001348 Binding of IL-10 and IL-10 receptor and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0000045 Binding of cytokine and cytokine receptors and conformational change of receptors in plasma membrane Combining with interleukin-10 to initiate a change in cell activity. http://purl.obolibrary.org/obo/IEV_0001352 Positive regulation of EGF signaling pathway http://purl.obolibrary.org/obo/IEV_0000836 Positive regulation of RTK signaling pathway Any process that activates or increases the rate, frequency or extent of epidermal growth factor receptor signaling pathway activity. http://purl.obolibrary.org/obo/IEV_0001354 Activation of c-Raf1 by PKC beta in cytosol http://purl.obolibrary.org/obo/IEV_0002485 Activation of Raf-1 by PKC in cytosol cPKCs (a and b1) have the potential to activate c-Raf1 in vivo while at the same time blocking further activation by growth factors and other PKC isotypes. http://purl.obolibrary.org/obo/IEV_0001356 Raf activation signaling (through RKIP) http://purl.obolibrary.org/obo/IEV_0001364 Raf activation signaling (through PKC) Protein kinase C (PKC) regulates activation of the Raf-1 signaling cascade by growth factors, but the mechanism by which this occurs has not been elucidated. Here we report that one mechanism involves dissociation of Raf kinase inhibitory protein (RKIP) from Raf-1. Classic and atypical but not novel PKC isoforms phosphorylate RKIP at serine 153 (Ser-153). http://purl.obolibrary.org/obo/IEV_0001357 Phosphorylation of RKIP by PKC in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol Classic and atypical but not novel PKC isoforms phosphorylate RKIP at serine 153 (Ser-153). http://purl.obolibrary.org/obo/IEV_0001359 Phosphorylation of RKIP by cPKC in cytosol http://purl.obolibrary.org/obo/IEV_0001357 Phosphorylation of RKIP by PKC in cytosol Classic and atypical but not novel PKC isoforms phosphorylate RKIP at serine 153 (Ser-153). http://purl.obolibrary.org/obo/IEV_0001372 Activation of IKK beta by PKC theta in cytosol http://purl.obolibrary.org/obo/IEV_0000291 Activation of IKK complex by PKC theta in cytosol T-cell lines expressing constitutively active PKC-theta, but not other constitutively active PKCs (alpha, delta, epsilon or zeta), were capable of activating an NF-kB reporter. Co-transfection experiments indicated that constitutively active PKC-theta upregulates the activity of IKKbeta, but not IKKalpha. Although a biochemical association between PKC-theta and IKKbeta could not be detected, the data suggest that PKC-theta directly or indirectly modulates IKKbeta kinase activity, thus regulating NF-kB. http://purl.obolibrary.org/obo/IEV_0001373 Phosphorylation of IKK complex by NIK in cytosol http://purl.obolibrary.org/obo/IEV_0000250 Phosphorylation of IKK complex by MAPKKK in cytosol TNRF signaling http://purl.obolibrary.org/obo/IEV_0001401 Regulation of Ras mediated signaling http://purl.obolibrary.org/obo/IEV_0000681 Regulation of small GTPase mediated signaling Any process that modulates the frequency, rate or extent of Ras protein signal transduction. http://purl.obolibrary.org/obo/IEV_0001402 Positive regulation of Ras mediated signaling http://purl.obolibrary.org/obo/IEV_0000682 Positive regulation of small GTPase mediated signaling Any process that activates or increases the rate, frequency or extent of Ras protein signal transduction. http://purl.obolibrary.org/obo/IEV_0001404 Negative regulation of cell cycle process http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. http://purl.obolibrary.org/obo/IEV_0001405 Positive regulation of cell cycle process http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. http://purl.obolibrary.org/obo/IEV_0001410 Alanine and aspartate metabolism http://purl.obolibrary.org/obo/IEV_0001556 Amino Acid Metabolism Alanine metabolism: The chemical reactions and pathways involving alanine, 2-aminopropanoic acid. Aspartate metabolism: The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid. http://purl.obolibrary.org/obo/IEV_0001412 Glycine, serine and threonine metabolism http://purl.obolibrary.org/obo/IEV_0001556 Amino Acid Metabolism Glycine metabolism: The chemical reactions and pathways involving glycine, aminoethanoic acid. Serine metabolism: The chemical reactions and pathways involving L-serine, the levorotatory isomer of 2-amino-3-hydroxypropanoic acid. Threonine metabolism: The chemical reactions and pathways involving threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins. http://purl.obolibrary.org/obo/IEV_0001413 Glycolysis and Gluconeogenesis http://purl.obolibrary.org/obo/IEV_0003811 Alcohol metabolism Glycolysis: The chemical reactions and pathways resulting in the breakdown of a monosaccharide (generally glucose) in other compounds, including pyruvate. Gluconeogenesis: The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. http://purl.obolibrary.org/obo/IEV_0001414 Pentose phosphate pathway http://purl.obolibrary.org/obo/IEV_0003811 Alcohol metabolism The process by which glucose is oxidized, coupled to NADPH synthesis. Glucose 6-P is oxidized with the formation of carbon dioxide (CO2), ribulose 5-phosphate and reduced NADP; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses. http://purl.obolibrary.org/obo/IEV_0001418 Galactose metabolism http://purl.obolibrary.org/obo/IEV_0003811 Alcohol metabolism The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose. http://purl.obolibrary.org/obo/IEV_0001419 Ascorbate and aldarate metabolism http://purl.obolibrary.org/obo/IEV_0003810 Carboxylic acid metabolism Ascorbate metabolism: The chemical reactions and pathways involving L-ascorbic acid, a carbohydrate-like vitamin containing six carbon atoms per molecule. Widely distributed in fruit and vegetables. http://purl.obolibrary.org/obo/IEV_0001429 Inositol metabolism http://purl.obolibrary.org/obo/IEV_0003811 Alcohol metabolism The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms. http://purl.obolibrary.org/obo/IEV_0001432 ATP synthesis http://purl.obolibrary.org/obo/IEV_0001450 Purine metabolism The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. http://purl.obolibrary.org/obo/IEV_0001436 Methane metabolism http://purl.obolibrary.org/obo/IEV_0001552 Energy Metabolism The chemical reactions and pathways involving methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes. http://purl.obolibrary.org/obo/IEV_0001440 Fatty acid elongation in mitochondria http://purl.obolibrary.org/obo/IEV_0001439 Fatty acid biosynthesis Fatty acid elongation: The elongation of a fatty acid chain by the sequential addition of two-carbon units. http://purl.obolibrary.org/obo/IEV_0001442 Ketone bodies metabolism http://purl.obolibrary.org/obo/IEV_0000818 Metabolic pathway The chemical reactions and pathways involving ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Although 3-hydroxybutyrate is not a ketone, it is classed as a ketone body because it exists in an equilibrium with acetoacetate. Ketone bodies may accumulate in excessive amounts in the body in starvation, diabetes mellitus or in other defects of carbohydrate metabolism. http://purl.obolibrary.org/obo/IEV_0001443 Steroid biosynthesis http://purl.obolibrary.org/obo/IEV_0001553 Lipid Metabolism The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. http://purl.obolibrary.org/obo/IEV_0001444 Bile acid biosynthesis http://purl.obolibrary.org/obo/IEV_0001553 Lipid Metabolism The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile. http://purl.obolibrary.org/obo/IEV_0001449 Arachidonic acid metabolism http://purl.obolibrary.org/obo/IEV_0001441 Fatty acid metabolism The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer. http://purl.obolibrary.org/obo/IEV_0001451 Pyrimidine metabolism http://purl.obolibrary.org/obo/IEV_0001554 Nucleotide Metabolism The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety. http://purl.obolibrary.org/obo/IEV_0001454 Valine, leucine and isoleucine degradation http://purl.obolibrary.org/obo/IEV_0001556 Amino Acid Metabolism Valine degradation: The chemical reactions and pathways resulting in the breakdown of valine, 2-amino-3-methylbutanoic acid. Leucine degradation: The chemical reactions and pathways resulting in the breakdown of leucine, 2-amino-4-methylpentanoic acid. Isoleucine degradation: The chemical reactions and pathways resulting in the breakdown of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid. http://purl.obolibrary.org/obo/IEV_0001458 Arginine and proline metabolism http://purl.obolibrary.org/obo/IEV_0001556 Amino Acid Metabolism Arginine metabolism: The chemical reactions and pathways involving arginine, 2-amino-5-guanidinopentanoic acid. Proline metabolism: The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins. http://purl.obolibrary.org/obo/IEV_0001459 Histidine metabolism http://purl.obolibrary.org/obo/IEV_0001556 Amino Acid Metabolism The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. http://purl.obolibrary.org/obo/IEV_0001461 Phenylalanine metabolism http://purl.obolibrary.org/obo/IEV_0001556 Amino Acid Metabolism L-phenylalanine metabolism: The chemical reactions and pathways involving L-phenylalanine, the levorotatory isomer of 2-amino-3-phenylpropanoic acid. http://purl.obolibrary.org/obo/IEV_0001464 Urea cycle and metabolism of amino groups http://purl.obolibrary.org/obo/IEV_0003813 Amide metabolism A cyclic metabolic pathway that converts waste nitrogen in the form of ammonium to urea. http://purl.obolibrary.org/obo/IEV_0001467 Aminophosphonate metabolism http://purl.obolibrary.org/obo/IEV_0001557 Amino acid derivative metabolism The chemical reactions and pathways involving aminophosphonates, amino acid derivatives that contain a phosphonic acid moiety. http://purl.obolibrary.org/obo/IEV_0001469 Cyanoamino acid metabolism http://purl.obolibrary.org/obo/IEV_0001557 Amino acid derivative metabolism The chemical reactions and pathways involving cyanoamino acids, amino acid derivatives that contain a cyanide group. http://purl.obolibrary.org/obo/IEV_0001470 D-Glutamine and D-glutamate metabolism http://purl.obolibrary.org/obo/IEV_0001410 Alanine and aspartate metabolism D-glutamine metabolism:The chemical reactions and pathways involving D-glutamine, the D-enantiomer of the amino acid glutamine, i.e. (2R)-2,5-diamino-5-oxopentanoic acid. D-glutamate metabolism:The chemical reactions and pathways involving D-glutamate, the D-enantiomer of the amino acid glutamate, i.e. (2R)-2-aminopentanedioic acid. http://purl.obolibrary.org/obo/IEV_0001471 D-Arginine and D-ornithine metabolism http://purl.obolibrary.org/obo/IEV_0001410 Alanine and aspartate metabolism D-arginine metabolism:The chemical reactions and pathways involving D-arginine, the D-enantiomer of the amino acid arginine, i.e. (2R)-2-amino-5-(carbamimidamido)pentanoic acid. D-ornithine metabolism:The chemical reactions and pathways involving D-ornithine, the D-enantiomer of the amino acid ornithine, i.e. (2R)-2,5-diaminopentanoic acid. http://purl.obolibrary.org/obo/IEV_0001478 Chondroitin sulfate biosynthesis http://purl.obolibrary.org/obo/IEV_0001438 Sulfur metabolism The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. http://purl.obolibrary.org/obo/IEV_0001490 Glycosaminoglycan degradation http://purl.obolibrary.org/obo/IEV_0001558 Glycan Biosynthesis and Metabolism The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars. http://purl.obolibrary.org/obo/IEV_0001491 Lipopolysaccharide biosynthesis http://purl.obolibrary.org/obo/IEV_0001553 Lipid Metabolism The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. http://purl.obolibrary.org/obo/IEV_0001508 Riboflavin metabolism http://purl.obolibrary.org/obo/IEV_0001555 Metabolism of Cofactors and Vitamins The chemical reactions and pathways involving riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). http://purl.obolibrary.org/obo/IEV_0001510 Nicotinate and nicotinamide metabolism http://purl.obolibrary.org/obo/IEV_0001554 Nucleotide Metabolism Nicotinamide metabolism: The chemical reactions and pathways involving nicotinamide, pyridine-3-carboxamide, the amide of nicotinic acid. It is a member of the B complex of vitamins and occurs widely in living organisms. http://purl.obolibrary.org/obo/IEV_0001512 Biotin metabolism http://purl.obolibrary.org/obo/IEV_0001438 Sulfur metabolism The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions. http://purl.obolibrary.org/obo/IEV_0001522 Indole and ipecac alkaloid biosynthesis http://purl.obolibrary.org/obo/IEV_0001560 Biosynthesis of Secondary Metabolites Indole biosynthesis: The chemical reactions and pathways resulting in the formation of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan). http://purl.obolibrary.org/obo/IEV_0001523 Stilbene, coumarine and lignin biosynthesis http://purl.obolibrary.org/obo/IEV_0001560 Biosynthesis of Secondary Metabolites Stilbene biosynthesis: The chemical reactions and pathways resulting in the formation of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA. Coumarin biosynthesis: The chemical reactions and pathways resulting in the formation of coumarins, a class of compounds derived from the phenylacrylic skeleton of cinnamic acids. Lignin biosynthesis: The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers. http://purl.obolibrary.org/obo/IEV_0001525 Alkaloid biosynthesis http://purl.obolibrary.org/obo/IEV_0001560 Biosynthesis of Secondary Metabolites The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases). http://purl.obolibrary.org/obo/IEV_0001529 Streptomycin biosynthesis http://purl.obolibrary.org/obo/IEV_0001422 Carbohydrate Metabolism The chemical reactions and pathways resulting in the formation of streptomycin, a commonly used antibiotic in cell culture media; it acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome. http://purl.obolibrary.org/obo/IEV_0001531 Clavulanic acid biosynthesis http://purl.obolibrary.org/obo/IEV_0001560 Biosynthesis of Secondary Metabolites The chemical reactions and pathways resulting in the formation of clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid. http://purl.obolibrary.org/obo/IEV_0001533 Novobiocin biosynthesis http://purl.obolibrary.org/obo/IEV_0001422 Carbohydrate Metabolism The chemical reactions and pathways resulting in the formation of novobiocin, a coumarin antibiotic produced by the bacterium gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase. http://purl.obolibrary.org/obo/IEV_0001535 Biphenyl degradation http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism The chemical reactions and pathways resulting in the breakdown of biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs). http://purl.obolibrary.org/obo/IEV_0001557 Amino acid derivative metabolism http://purl.obolibrary.org/obo/IEV_0003812 Amino acid and derivative metabolism The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents. http://purl.obolibrary.org/obo/IEV_0001559 Polyketide biosynthesis http://purl.obolibrary.org/obo/IEV_0003810 Carboxylic acid metabolism The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty-acid biosynthesis but without the intermediate reductive steps. http://purl.obolibrary.org/obo/IEV_0001637 Autophosphorylation of Src and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001607 Autophosphorylation of Src family and active conformational change in cytosol p416 http://purl.obolibrary.org/obo/IEV_0001673 Negative regulation of Toll-like receptor pathway http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway. http://purl.obolibrary.org/obo/IEV_0001674 Positive regulation of Toll-like receptor pathway http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway Any process that activates or increases the frequency, rate, or extent of toll-like receptor signaling pathway. http://purl.obolibrary.org/obo/IEV_0001676 Negative regulation of Wnt signaling pathway http://purl.obolibrary.org/obo/IEV_0001675 Regulation of Wnt signaling pathway Any process that stops, prevents or reduces the rate, frequency or extent of Wnt receptor signaling pathway activity. http://purl.obolibrary.org/obo/IEV_0001677 Positive regulation of Wnt signaling pathway http://purl.obolibrary.org/obo/IEV_0001675 Regulation of Wnt signaling pathway Any process that activates or increases the rate, frequency or extent of Wnt receptor signaling pathway activity. http://purl.obolibrary.org/obo/IEV_0001687 Regulation of IGF signaling pathway http://purl.obolibrary.org/obo/IEV_0000834 Regulation of RTK signaling pathway Any process that modulates the frequency, rate or extent of insulin-like growth factor receptor signaling. http://purl.obolibrary.org/obo/IEV_0001688 Negative regulation of IGF receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001687 Regulation of IGF signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of insulin-like growth factor receptor signaling. http://purl.obolibrary.org/obo/IEV_0001689 Positive regulation of IGF signaling pathway http://purl.obolibrary.org/obo/IEV_0000836 Positive regulation of RTK signaling pathway Any process that increases the frequency, rate or extent of insulin-like growth factor receptor signaling. http://purl.obolibrary.org/obo/IEV_0001763 Gene expression of PIAS4 (induced by TGF-beta) http://purl.obolibrary.org/obo/IEV_0000182 Gene expression Hep3B cells http://purl.obolibrary.org/obo/IEV_0001779 Regulation of Estrogen receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001776 Regulation of Steroid receptor signaling Any process that modulates the frequency, rate or extent of the activity of an estrogen receptor signaling pathway. http://purl.obolibrary.org/obo/IEV_0001783 Negative regulation of Estrogen receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001779 Regulation of Estrogen receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an estrogen receptor signaling pathway. http://purl.obolibrary.org/obo/IEV_0001784 Positive regulation of Estrogen receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001779 Regulation of Estrogen receptor signaling pathway Any process that activates or increases the frequency, rate or extent of the activity of an estrogen receptor signaling pathway. http://purl.obolibrary.org/obo/IEV_0001824 Smooth muscle cell differentiation http://purl.obolibrary.org/obo/IEV_0001823 Muscle cell differentiation The process whereby a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary. http://purl.obolibrary.org/obo/IEV_0001833 Regulation of transcription http://purl.obolibrary.org/obo/IEV_0001835 Regulation of gene expression Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA. http://purl.obolibrary.org/obo/IEV_0001834 Positive regulation of transcription http://purl.obolibrary.org/obo/IEV_0001833 Regulation of transcription Any process that activates or increases the frequency, rate or extent of transcription. http://purl.obolibrary.org/obo/IEV_0001835 Regulation of gene expression http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/IEV_0001836 Positive regulation of gene expression http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/IEV_0001838 Negative regulation of transcription http://purl.obolibrary.org/obo/IEV_0001833 Regulation of transcription Any process that stops, prevents or reduces the frequency, rate or extent of transcription. http://purl.obolibrary.org/obo/IEV_0001839 Negative regulation of translation http://purl.obolibrary.org/obo/IEV_0001841 Regulation of translation Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA. http://purl.obolibrary.org/obo/IEV_0001841 Regulation of translation http://purl.obolibrary.org/obo/IEV_0001835 Regulation of gene expression Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA. http://purl.obolibrary.org/obo/IEV_0001988 cAMP mediated signaling http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway A series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response. http://purl.obolibrary.org/obo/IEV_0002021 Adenylate cyclase activation signaling http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling Any process that initiates the activity of the inactive enzyme adenylate cyclase. http://purl.obolibrary.org/obo/IEV_0002095 Phosphorylation of JNK by MKK_p in cytosol http://purl.obolibrary.org/obo/IEV_0000478 Phosphorylation of MAPK by MAPKK in cytosol The initiation of the activity of the inactive enzyme JUN kinase by phosphorylation by a JUN kinase kinase (JNKK). http://purl.obolibrary.org/obo/IEV_0002159 Autophosphorylation of JAK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000052 Autophosphorylation of Jak in cytosol The process of introducing a phosphoric group to a tyrosine residue of a JAK2 (Janus Activated Kinase 2) protein, thereby activating it. http://purl.obolibrary.org/obo/IEV_0002262 LIF signaling pathway http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway The series of molecular signals generated as a consequence of a leukemia inhibitory factor receptor binding to one of its physiological ligands. http://purl.obolibrary.org/obo/IEV_0002334 Binding of IL-7 and IL-7 receptor and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0000045 Binding of cytokine and cytokine receptors and conformational change of receptors in plasma membrane Combining with interleukin-7 to initiate a change in cell activity. http://purl.obolibrary.org/obo/IEV_0002514 Negative regulation of Toll receptor signaling http://purl.obolibrary.org/obo/IEV_0003569 Regulation of Toll receptor signaling Any process that stops, prevents or reduces the frequency, rate or extent of the Tl signaling pathway. http://purl.obolibrary.org/obo/IEV_0002515 Positive regulation of Toll receptor signaling http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway Any process that activates or increases the frequency, rate or extent of the Tl signaling pathway. http://purl.obolibrary.org/obo/IEV_0002536 Mesodermal cell fate determination http://purl.obolibrary.org/obo/IEV_0002535 Cell fate determination Process by which a cell becomes capable of differentiating autonomously into a mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed. http://purl.obolibrary.org/obo/IEV_0002541 Endodermal cell fate determination http://purl.obolibrary.org/obo/IEV_0002535 Cell fate determination Process by which a cell becomes capable of differentiating autonomously into an endoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed. http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0000913 Transference The covalent attachment of a glycosyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological polymer. Reaction that can affect Ser, Thr, Cys, Arg, and Asn residues. This reaction is known to be reversible in the case of Asn substrate. http://purl.obolibrary.org/obo/IEV_0002608 Cell-cell signaling involved in cell fate commitment http://purl.obolibrary.org/obo/IEV_0002611 Cell-cell signaling Signaling at long or short range between cells that results in the commitment of a cell to a certain fate. http://purl.obolibrary.org/obo/IEV_0002609 Induction http://purl.obolibrary.org/obo/IEV_0002608 Cell-cell signaling involved in cell fate commitment Signaling at short range between cells or tissues of different ancestry and developmental potential that results in one cell or tissue effecting a developmental change in the other. http://purl.obolibrary.org/obo/IEV_0002611 Cell-cell signaling http://purl.obolibrary.org/obo/IEV_0001319 Cell communication Any process that mediates the transfer of information from one cell to another. http://purl.obolibrary.org/obo/IEV_0002626 FGF receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0000830 RTK signaling pathway The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands. http://purl.obolibrary.org/obo/IEV_0002627 HGF receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0000830 RTK signaling pathway The series of molecular signals generated as a consequence of the hepatocyte growth factor receptor binding to one of its physiological ligands. http://purl.obolibrary.org/obo/IEV_0002632 VEGF receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0000830 RTK signaling pathway The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands. http://purl.obolibrary.org/obo/IEV_0002661 Covalent binding http://purl.obolibrary.org/obo/IEV_0000004 Binding Interaction leading to the formation of covalent bond within an autocatalytic molecule or between partners. http://purl.obolibrary.org/obo/IEV_0002662 Colocalization http://purl.obolibrary.org/obo/IEV_0001886 Molecular interaction co-occurrence of interactors in a limited subcellular location or similar distribution in various regions of a cell. http://purl.obolibrary.org/obo/IEV_0002665 DNA cleavage http://purl.obolibrary.org/obo/IEV_0003607 nucleic acid cleavage Covalent bond breakage of a DNA molecule leading to the formation of smaller fragements. http://purl.obolibrary.org/obo/IEV_0002667 Defarnesylation http://purl.obolibrary.org/obo/IEV_0002666 lipid cleavage S-farnesyl-L-cysteined is cleaved and returns a C residue. http://purl.obolibrary.org/obo/IEV_0002668 Degeranylation http://purl.obolibrary.org/obo/IEV_0002666 lipid cleavage S-geranylgeranyl-L-cysteine is cleaved and returns a C residue. http://purl.obolibrary.org/obo/IEV_0002669 Demyristoylation http://purl.obolibrary.org/obo/IEV_0002666 lipid cleavage N6-myristoyl-L-lysine is cleaved and returns a K residue. http://purl.obolibrary.org/obo/IEV_0002670 Depalmitoylation http://purl.obolibrary.org/obo/IEV_0002666 lipid cleavage S-palmitoyl-L-cysteine, N6-palmitoyl-L-lysine, O-palmitoyl-L-threonine or O-palmitoyl-L-serine are cleaved and return C,K,T or S residues. http://purl.obolibrary.org/obo/IEV_0002672 Protein cleavage http://purl.obolibrary.org/obo/IEV_0002571 Cleavage Covalent modification of a polypeptide occuring during its maturation or its proteolytic degradation. http://purl.obolibrary.org/obo/IEV_0002674 Formylation http://purl.obolibrary.org/obo/IEV_0000913 Transference Reaction that can affect K or G residues. http://purl.obolibrary.org/obo/IEV_0002676 Deformylation http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis N6-formyl-L-lysine is cleaved and returns a K residue. http://purl.obolibrary.org/obo/IEV_0002679 Desumoylation http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis Cleavage of the G-K bond and release of the SUMO ubiquitin like proteins. http://purl.obolibrary.org/obo/IEV_0002680 Deubiquitination http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis Cleavage of the G-K bond and release of ubiquitin or ubiquitin like proteins. http://purl.obolibrary.org/obo/IEV_0002681 lipid addition http://purl.obolibrary.org/obo/IEV_0000913 Transference Covalent or non covalent binding of lipid group on a protein residue. http://purl.obolibrary.org/obo/IEV_0002699 Nervous System Malformation http://purl.obolibrary.org/obo/IEV_0002701 Nervous System Disease Structural abnormalities of the central or peripheral nervous system resulting primarily from defects of embryogenesis. http://purl.obolibrary.org/obo/IEV_0002704 Morphogenesis of embryonic epithelium http://purl.obolibrary.org/obo/IEV_0000574 Embryonic morphogenesis The process by which the anatomical structures of embryonic epithelia are generated and organized. Morphogenesis pertains to the creation of form. http://purl.obolibrary.org/obo/IEV_0002705 Embryonic epithelial tube formation http://purl.obolibrary.org/obo/IEV_0002704 Morphogenesis of embryonic epithelium The morphogenesis of an embryonic epithelium into a tube-shaped structure. http://purl.obolibrary.org/obo/IEV_0002706 Morphogenesis of an epithelium http://purl.obolibrary.org/obo/IEV_0000447 Anatomical structure morphogenesis The process by which the anatomical structures of epithelia are generated and organized. Morphogenesis pertains to the creation of form. An epithelium is a sheet of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube. http://purl.obolibrary.org/obo/IEV_0002707 Neural tube formation http://purl.obolibrary.org/obo/IEV_0002705 Embryonic epithelial tube formation The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system. http://purl.obolibrary.org/obo/IEV_0002709 Neural plate morphogenesis http://purl.obolibrary.org/obo/IEV_0002704 Morphogenesis of embryonic epithelium The process by which the anatomical structures of the neural plate are generated and organized. Morphogenesis pertains to the creation of form. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue. http://purl.obolibrary.org/obo/IEV_0002710 Nervous system development http://purl.obolibrary.org/obo/IEV_0003794 System development The origin and formation of nervous tissue. http://purl.obolibrary.org/obo/IEV_0002711 Tube morphogenesis http://purl.obolibrary.org/obo/IEV_0000447 Anatomical structure morphogenesis The process by which the anatomical structures of a tube are generated and organized. Morphogenesis pertains to the creation of form. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. http://purl.obolibrary.org/obo/IEV_0002713 Tube development http://purl.obolibrary.org/obo/IEV_0003795 Anatomical structure development The process whose specific outcome is the progression of a tube over time, from its intial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts. http://purl.obolibrary.org/obo/IEV_0002720 nonenzymatic reaction http://purl.obolibrary.org/obo/IEV_0000221 Metabolic reaction The reaction direction shown, that is, A + B <==> C + D versus C + D <==> A + B, is in accordance with the direction of the reaction within a pathway. This reaction occurs spontaneously -- no enzyme is required. http://purl.obolibrary.org/obo/IEV_0003392 Phosphotransfer http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation Reaction where a phosphate is transferred between two proteins of a phosphorelay system. http://purl.obolibrary.org/obo/IEV_0003393 synthetic interaction http://purl.obolibrary.org/obo/IEV_0002682 genetic interaction The phenotype resulting from genetic perturbation A and the phenotype resulting from genetic perturbation B have no effect on the WT background, but the combined genetic perturbation of A and B has a phenotypic effect. http://purl.obolibrary.org/obo/IEV_0003395 suppressive interaction http://purl.obolibrary.org/obo/IEV_0002682 genetic interaction The phenotype resulting from genetic perturbation of A has an effect on WT, but that effect is abolished by adding the suppressor B, which itself shows no single-mutant effect (for example, WT = B = AB < A). http://purl.obolibrary.org/obo/IEV_0003397 conditional interaction http://purl.obolibrary.org/obo/IEV_0002682 genetic interaction The phenotype resulting from genetic perturbation of A has an effect only in the B background, or the B mutant has an effect only in the A background. http://purl.obolibrary.org/obo/IEV_0003398 enhancement interaction http://purl.obolibrary.org/obo/IEV_0003399 additive interaction The A genetic perturbation enhances the phenotype of the B perturbation, or vice versa (e.g. WT = A < B < AB or WT = B < A < AB). This could be conditional or additive by the above scheme. http://purl.obolibrary.org/obo/IEV_0003399 additive interaction http://purl.obolibrary.org/obo/IEV_0002682 genetic interaction Single-mutant phenotype effects combine to give a double-mutant effect different from the wild type and different from single mutant effect. For instance WT < A= B < AB, B < WT = AB < A, WT < A < B < AB, B < WT < AB < A, and all additional inequalities obtained by interchanging A and B, or reversing the effect of both A and B. http://purl.obolibrary.org/obo/IEV_0003400 single nonmonotonic interaction http://purl.obolibrary.org/obo/IEV_0002682 genetic interaction The phenotype resulting from genetic perturbation of B shows opposing effects in the WT and A backgrounds (for example, B > WT and AB< A); or, A shows opposing effects in the WT and B backgrounds, but not both. http://purl.obolibrary.org/obo/IEV_0003401 double nonmonotonic interaction http://purl.obolibrary.org/obo/IEV_0002682 genetic interaction The phenotype resulting from genetic perturbation of both A and B show opposing effects in the WT background and the background with the other mutant gene. http://purl.obolibrary.org/obo/IEV_0003446 Demethylation http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis The cleavage of a methyl group from a polypeptide. Methylation is generally an irreversible reaction except in mamalian. http://purl.obolibrary.org/obo/IEV_0003447 nucleoside triphosphatase reaction http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis Catalysis of the hydrolisis of a nucleoside triphosphate into a nucleoside diphosphate plus phosphate. http://purl.obolibrary.org/obo/IEV_0003448 atpase reaction http://purl.obolibrary.org/obo/IEV_0003447 nucleoside triphosphatase reaction Catalysis of the hydrolisis of ATP+ H2O = ADP + phosphate. http://purl.obolibrary.org/obo/IEV_0003449 gtpase reaction http://purl.obolibrary.org/obo/IEV_0003447 nucleoside triphosphatase reaction Catalysis of the hydrolisis of GTP+ H2O = GDP + phosphate. http://purl.obolibrary.org/obo/IEV_0003569 Regulation of Toll receptor signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway Any process that modulates the frequency, rate or extent of the Tl signaling pathway. http://purl.obolibrary.org/obo/IEV_0003593 Binding of TGF beta super family:Type II receptor and Type I receptor in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane The aggregation and bonding together of a type II transforming growth factor beta (TGFbeta) receptor dimer with a type I TGFbeta receptor dimer, following ligand binding, to form a heterotetrameric TGFbeta receptor complex. http://purl.obolibrary.org/obo/IEV_0003606 RNA cleavage http://purl.obolibrary.org/obo/IEV_0003607 nucleic acid cleavage Any process by which an RNA molecule is cleaved at specific sites or in a regulated manner. http://purl.obolibrary.org/obo/IEV_0003607 nucleic acid cleavage http://purl.obolibrary.org/obo/IEV_0002571 Cleavage Covalent bond breakage of a nucleic acid molecule leading to the formation of smaller fragments. http://purl.obolibrary.org/obo/IEV_0003671 Skeletal muscle atrophy http://purl.obolibrary.org/obo/IEV_0003662 Muscle system process A process, occurring in skeletal muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse. http://purl.obolibrary.org/obo/IEV_0003742 Eye development http://purl.obolibrary.org/obo/IEV_0002712 Organ development The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight. http://purl.obolibrary.org/obo/IEV_0003748 Multicellular organism reproduction http://purl.obolibrary.org/obo/IEV_0001327 Multicellular organismal process The biological process by which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. http://purl.obolibrary.org/obo/IEV_0003759 Regulation of Hedgehog signaling pathway http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway Any process that modulates the frequency, rate or extent of smoothened signaling. http://purl.obolibrary.org/obo/IEV_0003760 Negative regulation of Hedgehog signaling pathway http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling. http://purl.obolibrary.org/obo/IEV_0003780 Hedgehog cleavage and lipidation http://purl.obolibrary.org/obo/IEV_0002721 enzymatic reaction It is further processed by internal cleavage to generate a 19-kDa N-terminal fragment (N-Hh) and a 25-kDa C-terminal fragment (C-Hh) with the concomitant addition of cholesterol at the C-terminus of N-Hh (N-Hhchol). http://purl.obolibrary.org/obo/IEV_0003791 Open tracheal system development http://purl.obolibrary.org/obo/IEV_0003792 Respiratory system development The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/IEV_0003792 Respiratory system development http://purl.obolibrary.org/obo/IEV_0003794 System development The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange. http://purl.obolibrary.org/obo/IEV_0003793 Trachea development http://purl.obolibrary.org/obo/IEV_0002712 Organ development The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches. http://purl.obolibrary.org/obo/IEV_0003794 System development http://purl.obolibrary.org/obo/IEV_0003795 Anatomical structure development The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. http://purl.obolibrary.org/obo/IEV_0003797 Reproductive structure development http://purl.obolibrary.org/obo/IEV_0003795 Anatomical structure development The reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures. http://purl.obolibrary.org/obo/IEV_0003798 Sex differentiation http://purl.obolibrary.org/obo/IEV_0003799 Reproductive developmental process The establishment of the sex of an organism by physical differentiation. http://purl.obolibrary.org/obo/IEV_0003799 Reproductive developmental process http://purl.obolibrary.org/obo/IEV_0000083 Development A developmental process by which a progressive change in the state of some part of an organism specifically contributes to its ability to form offspring. http://purl.obolibrary.org/obo/IEV_0003801 Negative regulation of FGF receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0000835 Negative regulation of RTK signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity. http://purl.obolibrary.org/obo/IEV_0003803 BMK cascade http://purl.obolibrary.org/obo/IEV_0000445 MAPKKK cascade A cascade of protein kinase activities, culminating in the phosphorylation and activation of big MAP kinase (BMK1/ERK5), which is a type of mitogen-activated protein (MAP) kinase. http://purl.obolibrary.org/obo/IEV_0003805 Nonribosomal peptide biosynthesis http://purl.obolibrary.org/obo/IEV_0000818 Metabolic pathway The biosynthetic process whereby peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione. http://purl.obolibrary.org/obo/IEV_0003808 Circadian behavior http://purl.obolibrary.org/obo/IEV_0001328 Rhythmic behavior The specific actions or reactions of an organism that recur with a regularity of approximately 24 hours. http://purl.obolibrary.org/obo/IEV_0003815 CoA biosynthesis http://purl.obolibrary.org/obo/IEV_0001554 Nucleotide Metabolism CoA biosynthesis: The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester. http://purl.obolibrary.org/obo/IEV_0003880 NK cell activation http://purl.obolibrary.org/obo/IEV_0003879 lymphocyte activation The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/IEV_0003883 Ectoderm development http://purl.obolibrary.org/obo/IEV_0003796 Tissue development The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation. http://purl.obolibrary.org/obo/IEV_0003906 Skin development http://purl.obolibrary.org/obo/IEV_0003914 Epidermis development The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. http://purl.obolibrary.org/obo/IEV_0003907 Male gonad development http://purl.obolibrary.org/obo/IEV_0002712 Organ development The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/IEV_0003908 chemotaxis http://purl.obolibrary.org/obo/IEV_0001336 Response to external stimulus The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). http://purl.obolibrary.org/obo/IEV_0003909 mitosis http://purl.obolibrary.org/obo/IEV_0001322 Organelle organization A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell. http://purl.obolibrary.org/obo/IEV_0003910 Epithelial cell differentiation http://purl.obolibrary.org/obo/IEV_0000002 Cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium. http://purl.obolibrary.org/obo/IEV_0003912 Epithelium development http://purl.obolibrary.org/obo/IEV_0003796 Tissue development The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. http://purl.obolibrary.org/obo/IEV_0003913 Endothelium development http://purl.obolibrary.org/obo/IEV_0003912 Epithelium development The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. An endothelium is an epithelium that lines an anatomical structure. http://purl.obolibrary.org/obo/IEV_0003915 Palate development http://purl.obolibrary.org/obo/IEV_0003795 Anatomical structure development The biological process whose specific outcome is the progression of the palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The palate is the partition that separates the nasal and oral cavities. http://purl.obolibrary.org/obo/IEV_0001360 Phosphorylation of RKIP by aPKC in cytosol http://purl.obolibrary.org/obo/IEV_0001357 Phosphorylation of RKIP by PKC in cytosol Classic and atypical but not novel PKC isoforms phosphorylate RKIP at serine 153 (Ser-153). http://purl.obolibrary.org/obo/IEV_0003490 Toll receptor signaling http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway The series of molecular signals initiated by binding of a ligand to an extracellular ligand to the Toll receptor on the surface of the target cell. http://purl.obolibrary.org/obo/IEV_0002581 Intercellular transport http://purl.obolibrary.org/obo/IEV_0000009 Translocation The movement of substances between cells in a multicellular organism. http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002721 enzymatic reaction EC:3 catalyzed process http://purl.obolibrary.org/obo/IEV_0001179 Negative regulation of Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway Any process that stops, prevents or reduces the rate, frequency or extent of the Notch signaling pathway. http://purl.obolibrary.org/obo/IEV_0001555 Metabolism of Cofactors and Vitamins http://purl.obolibrary.org/obo/IEV_0000818 Metabolic pathway Cofactor metabolism: The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. Vitamin metabolism: The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems. http://purl.obolibrary.org/obo/IEV_0000830 RTK signaling pathway http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand. http://purl.obolibrary.org/obo/IEV_0000863 BMP signaling pathway http://purl.obolibrary.org/obo/IEV_0000090 TGF beta super family signaling pathway A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor. http://purl.obolibrary.org/obo/IEV_0000882 Regulation of BMP signaling pathway http://purl.obolibrary.org/obo/IEV_0000876 Regulation of TGF beta super family signaling pathway (through p38 cascade) Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway. http://purl.obolibrary.org/obo/IEV_0000919 Farnesylation http://purl.obolibrary.org/obo/IEV_0000921 Isoprenylation Reversible reaction that can affect C residue. http://purl.obolibrary.org/obo/IEV_0001259 Rac mediated signaling http://purl.obolibrary.org/obo/IEV_0000676 Small GTPase mediated signaling A series of molecular signals within the cell that are mediated by a member of the Rac family of proteins switching to a GTP-bound active state. http://purl.obolibrary.org/obo/IEV_0001505 Receptor internalization http://purl.obolibrary.org/obo/IEV_0000009 Translocation The process by which cell surface receptors are monoubiquitinated following ligand-induced activation, and subsequently taken up into endocytic vesicles and targeted to the lysosome or vacuole for degradation; serves as a mechanism to downregulate receptor signaling. http://purl.obolibrary.org/obo/IEV_0001530 Tetracycline biosynthesis http://purl.obolibrary.org/obo/IEV_0001560 Biosynthesis of Secondary Metabolites The formation from simpler components of tetracycline, a broad spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles). http://purl.obolibrary.org/obo/IEV_0001536 Toluene and xylene degradation http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism Toluene degradation: The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products. Xylene degradation: The chemical reactions and pathways resulting in the breakdown of xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene. http://purl.obolibrary.org/obo/IEV_0000101 Programmed cell death http://purl.obolibrary.org/obo/IEV_0000097 Cell death Cell death resulting from activation of endogenous cellular processes. http://purl.obolibrary.org/obo/IEV_0002258 Actin filament reorganization during cell cycle http://purl.obolibrary.org/obo/IEV_0001324 Actin filament organization Rearrangement of the spatial distribution of actin filaments and associated proteins that accompanies progression of the cell cycle. http://purl.obolibrary.org/obo/IEV_0002610 Lateral inhibition http://purl.obolibrary.org/obo/IEV_0002608 Cell-cell signaling involved in cell fate commitment Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells. http://purl.obolibrary.org/obo/IEV_0000474 Phosphorylation of MAPKK by MAPKKK in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol The initiation of the activity of the inactive enzyme MAP kinase kinase by phosphorylation by a MAPKKK. http://purl.obolibrary.org/obo/IEV_0000865 EGF receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0000830 RTK signaling pathway The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands. http://purl.obolibrary.org/obo/IEV_0001231 Steroid receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway Any series of molecular signals generated as a consequence of a steroid hormone binding to its receptor. http://purl.obolibrary.org/obo/IEV_0000577 Flower morphogenesis http://purl.obolibrary.org/obo/IEV_0000575 Post-embryonic morphogenesis The process by which the anatomical structures of the flower are generated and organized. Morphogenesis pertains to the creation of form. http://purl.obolibrary.org/obo/IEV_0000648 Y-27632 medication http://purl.obolibrary.org/obo/IEV_0000292 Medication Inhibitor of p160ROCK http://purl.obolibrary.org/obo/IEV_0000661 GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand. http://purl.obolibrary.org/obo/IEV_0000717 Whooping cough http://purl.obolibrary.org/obo/IEV_0000075 Disease A respiratory infection caused by BORDETELLA PERTUSSIS and characterized by paroxysmal coughing ending in a prolonged crowing intake of breath. http://purl.obolibrary.org/obo/IEV_0001017 DNA fragmentation during apoptosis http://purl.obolibrary.org/obo/IEV_0001104 DNA damage The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments. http://purl.obolibrary.org/obo/IEV_0001095 S phase http://purl.obolibrary.org/obo/IEV_0000366 Cell cycle process Progression through S phase, the part of the cell cycle during which DNA synthesis takes place. http://purl.obolibrary.org/obo/IEV_0001258 Ras mediated signaling http://purl.obolibrary.org/obo/IEV_0000676 Small GTPase mediated signaling A series of molecular signals within the cell that are mediated by a member of the Ras family of proteins switching to a GTP-bound active state. http://purl.obolibrary.org/obo/IEV_0001273 Regulation of B cell receptor signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell. http://purl.obolibrary.org/obo/IEV_0001492 Peptidoglycan biosynthesis http://purl.obolibrary.org/obo/IEV_0001558 Glycan Biosynthesis and Metabolism The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls. http://purl.obolibrary.org/obo/IEV_0001507 Thiamine metabolism http://purl.obolibrary.org/obo/IEV_0001438 Sulfur metabolism The chemical reactions and pathways involving thiamin (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver. http://purl.obolibrary.org/obo/IEV_0001511 Pantothenate biosynthesis http://purl.obolibrary.org/obo/IEV_0001555 Metabolism of Cofactors and Vitamins The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods. http://purl.obolibrary.org/obo/IEV_0001514 Folate metabolism http://purl.obolibrary.org/obo/IEV_0001556 Amino Acid Metabolism The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines. http://purl.obolibrary.org/obo/IEV_0001517 Ubiquinone biosynthesis http://purl.obolibrary.org/obo/IEV_0001555 Metabolism of Cofactors and Vitamins The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme. http://purl.obolibrary.org/obo/IEV_0001518 Terpenoid biosynthesis http://purl.obolibrary.org/obo/IEV_0001553 Lipid Metabolism The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure. http://purl.obolibrary.org/obo/IEV_0001519 Monoterpenoid biosynthesis http://purl.obolibrary.org/obo/IEV_0001553 Lipid Metabolism The chemical reactions and pathways resulting in the formation of monoterpenoid compounds, terpenoids having a C10 skeleton. http://purl.obolibrary.org/obo/IEV_0001524 Flavonoid biosynthesis http://purl.obolibrary.org/obo/IEV_0001560 Biosynthesis of Secondary Metabolites The chemical reactions and pathways resulting in the formation of flavonoids, a group of phenolic derivatives containing a flavan skeleton. http://purl.obolibrary.org/obo/IEV_0001527 Penicillins and cephalosporins biosynthesis http://purl.obolibrary.org/obo/IEV_0001438 Sulfur metabolism Penicillin biosynthesis: The chemical reactions and pathways resulting in the formation of any antibiotic that contains the condensed beta-lactamthiazolidine ring system. Cephalosporin biosynthesis: The formation from simpler components of a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria. http://purl.obolibrary.org/obo/IEV_0001534 Caprolactam degradation http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism The chemical reactions and pathways resulting in the breakdown of caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid. http://purl.obolibrary.org/obo/IEV_0000393 DNA replication http://purl.obolibrary.org/obo/IEV_0000071 Molecular event The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. http://purl.obolibrary.org/obo/IEV_0000397 Embryonic development http://purl.obolibrary.org/obo/IEV_0000083 Development The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. http://purl.obolibrary.org/obo/IEV_0000460 T cell receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell. http://purl.obolibrary.org/obo/IEV_0001539 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane degradation http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism The chemical reactions and pathways resulting in the breakdown of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide. http://purl.obolibrary.org/obo/IEV_0001540 2,4-Dichlorobenzoate degradation http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs). http://purl.obolibrary.org/obo/IEV_0003745 Multicellular organismal development http://purl.obolibrary.org/obo/IEV_0001327 Multicellular organismal process The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/IEV_0001881 Tryptophan biosynthesis http://purl.obolibrary.org/obo/IEV_0001462 Tryptophan metabolism The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid. http://purl.obolibrary.org/obo/IEV_0003790 Mesoderm migration http://purl.obolibrary.org/obo/IEV_0000104 Cell migration The migration of mesodermal cells during gastrulation to help establish the multilayered body plan of the organism. http://purl.obolibrary.org/obo/IEV_0000637 Actin polymerization and/or depolymerization http://purl.obolibrary.org/obo/IEV_0000092 Cytoskeleton organization Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament. http://purl.obolibrary.org/obo/IEV_0002534 Filopodium formation http://purl.obolibrary.org/obo/IEV_0001320 Cellular component organization The assembly of a filopodium, a very long microspike extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or by the growth cone of a developing nerve cell axon. http://purl.obolibrary.org/obo/IEV_0000872 DNA repair http://purl.obolibrary.org/obo/IEV_0000071 Molecular event The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0002721 enzymatic reaction EC:6 catalyzed process http://purl.obolibrary.org/obo/IEV_0001275 Positive regulation of B cell receptor signaling http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway Any process that activates or increases the rate, frequency or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell. http://purl.obolibrary.org/obo/IEV_0001430 Inositol phosphate metabolism http://purl.obolibrary.org/obo/IEV_0001429 Inositol metabolism The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached. http://purl.obolibrary.org/obo/IEV_0001681 Deacetylation http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis N6-acetyl-L-lysine or S-acetyl-L-cysteine are cleaved and return K or C residues. http://purl.obolibrary.org/obo/IEV_0001493 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis http://purl.obolibrary.org/obo/IEV_0001448 Glycerophospholipid metabolism The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol moiety is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate moiety, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage. http://purl.obolibrary.org/obo/IEV_0002570 Hedgehog signaling pathway http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened. http://purl.obolibrary.org/obo/IEV_0000076 Cell proliferation http://purl.obolibrary.org/obo/IEV_0000069 Cellular event The multiplication or reproduction of cells, resulting in the rapid expansion of a cell population. http://purl.obolibrary.org/obo/IEV_0000291 Activation of IKK complex by PKC theta in cytosol http://purl.obolibrary.org/obo/IEV_0002317 Activation of IKK complex by PKCs in cytosol The Physical Association of Protein Kinase Ctheta with a Lipid Raft-Associated Inhibitor of kB Factor Kinase (IKK) Complex Plays a Role in the Activation of the NF-kB Cascade by TCR and CD28. http://purl.obolibrary.org/obo/IEV_0000739 Ion transport through ion channel http://purl.obolibrary.org/obo/IEV_0000009 Translocation The directed movement of charged atoms or small charged molecules into, out of, within or between cells. http://purl.obolibrary.org/obo/IEV_0001400 Regulation of Toll-like receptor pathway http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway. http://purl.obolibrary.org/obo/IEV_0001358 Dissociation of RKIP and Raf1 in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol Protein kinase C (PKC) regulates activation of the Raf-1 signaling cascade by growth factors, but the mechanism by which this occurs has not been elucidated. Here we report that one mechanism involves dissociation of Raf kinase inhibitory protein (RKIP) from Raf-1. http://purl.obolibrary.org/obo/IEV_0001316 G2 phase http://purl.obolibrary.org/obo/IEV_0000366 Cell cycle process Progression through G2 phase, one of two 'gap' phases in the cell cycle; G2 is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis). http://purl.obolibrary.org/obo/IEV_0000479 Phosphorylation of transcriptional regulator by MAPK_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001082 Phosphorylation in inner space of nucleus Dually phosphorylated MAPK, or dpERK, phosphorylates protein targets in both the cytoplasm and nucleus. http://purl.obolibrary.org/obo/IEV_0001509 Vitamin B6 metabolism http://purl.obolibrary.org/obo/IEV_0001555 Metabolism of Cofactors and Vitamins The chemical reactions and pathways involving any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate. http://purl.obolibrary.org/obo/IEV_0003879 lymphocyte activation http://purl.obolibrary.org/obo/IEV_0003878 Cell activation A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/IEV_0002671 mRNA cleavage http://purl.obolibrary.org/obo/IEV_0003606 RNA cleavage Any process by which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner. http://purl.obolibrary.org/obo/IEV_0003743 Compound eye development http://purl.obolibrary.org/obo/IEV_0003742 Eye development The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/IEV_0001337 Response to stress http://purl.obolibrary.org/obo/IEV_0001332 Response to stimulus A change in state or activity of an organism or cell (in terms of movement, secretion, enzyme production, gene expression, etc.) that occurs in response to stress, usually, but not necessarily exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/IEV_0000047 Dimerization of STAT in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol The formation of a dimer of two STAT proteins (Signal Transducers and Activators of Transcription) following their activation by members of the janus activated kinase (JAK) family of tyrosine kinases. http://purl.obolibrary.org/obo/IEV_0003810 Carboxylic acid metabolism http://purl.obolibrary.org/obo/IEV_0000818 Metabolic pathway The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000145 Regulation pathway Any process that modulates the frequency, rate or extent of a signaling pathway. http://purl.obolibrary.org/obo/IEV_0003391 Elongation http://purl.obolibrary.org/obo/IEV_0000913 Transference The process by which a DNA strand is synthesized from template DNA by the action of polymerases, which add nucleotides to the 3' end of the nascent DNA strand. http://purl.obolibrary.org/obo/IEV_0000633 Phosphorylation of MAPKKK by MAPKKKK in cytosol http://purl.obolibrary.org/obo/IEV_0002086 Phosphorylation of MAPKKK by non-receptor serine/threonine kinase in cytosol Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase. http://purl.obolibrary.org/obo/IEV_0001417 Fructose and mannose metabolism http://purl.obolibrary.org/obo/IEV_0003811 Alcohol metabolism Fructose metabolism: The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey. Mannose metabolism: The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins. http://purl.obolibrary.org/obo/IEV_0000548 Regulation of insulin receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway Any process that modulates the frequency, rate or extent of insulin receptor signaling. http://purl.obolibrary.org/obo/IEV_0000080 Transdifferentiation http://purl.obolibrary.org/obo/IEV_0000002 Cell differentiation The conversion of a differentiated cell of one fate into a differentiated cell of another fate without first undergoing cell division or reversion to a more primitive or stem cell-like fate. http://purl.obolibrary.org/obo/IEV_0000578 Tissue regeneration http://purl.obolibrary.org/obo/IEV_0003796 Tissue development The regrowth of lost or destroyed tissues. http://purl.obolibrary.org/obo/IEV_0000723 Heterotrimeric GPCR signaling pathway (through photon, rhodopsin, G alpha t and cGMP PDE) http://purl.obolibrary.org/obo/IEV_0002636 Heterotrimeric GPCR signaling pathway (through G alpha t) The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon. http://purl.obolibrary.org/obo/IEV_0003382 Cell division http://purl.obolibrary.org/obo/IEV_0000069 Cellular event The processes resulting in the physical partitioning and separation of a cell into daughter cells. http://purl.obolibrary.org/obo/IEV_0000774 Circadian rhythm http://purl.obolibrary.org/obo/IEV_0003807 Rhythmic process Any biological process in an organism that recurs with a regularity of approximately 24 hours. http://purl.obolibrary.org/obo/IEV_0000002 Cell differentiation http://purl.obolibrary.org/obo/IEV_0000069 Cellular event The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. http://purl.obolibrary.org/obo/IEV_0001272 Complex formation of B cell coreceptor in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane The B cell coreceptor complex, which is defined by its ability to bind and respond to C3d(g)-bound antigen, is composed of CD19, CD21 and the widely expressed CD81 and Leu13 proteins. http://purl.obolibrary.org/obo/IEV_0002721 enzymatic reaction http://purl.obolibrary.org/obo/IEV_0000221 Metabolic reaction Terms aiming to represent biochemical reactions referring to their resulting product modifications. http://purl.obolibrary.org/obo/IEV_0000077 Cell cycle http://purl.obolibrary.org/obo/IEV_0000069 Cellular event The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. http://purl.obolibrary.org/obo/IEV_0002701 Nervous System Disease http://purl.obolibrary.org/obo/IEV_0000075 Disease Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle. http://purl.obolibrary.org/obo/IEV_0000162 Estrogen receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001231 Steroid receptor signaling pathway Any series of molecular signals generated as a consequence of an estrogen binding to its receptor. http://purl.obolibrary.org/obo/IEV_0003807 Rhythmic process http://purl.obolibrary.org/obo/IEV_0000082 Organism event Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism. http://purl.obolibrary.org/obo/IEV_0001494 Sphingolipid metabolism http://purl.obolibrary.org/obo/IEV_0001553 Lipid Metabolism The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). http://purl.obolibrary.org/obo/IEV_0000864 TGF beta signaling pathway http://purl.obolibrary.org/obo/IEV_0000090 TGF beta super family signaling pathway The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands. http://purl.obolibrary.org/obo/IEV_0000549 Positive regulation of insulin receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway Any process that increases the frequency, rate or extent of insulin receptor signaling. http://purl.obolibrary.org/obo/IEV_0000072 Dormancy http://purl.obolibrary.org/obo/IEV_0001330 Physiological event The process by which a dormant state is induced, maintained and broken. Dormancy is characterized by a suspension of physiological activity. http://purl.obolibrary.org/obo/IEV_0001820 Blood circulation http://purl.obolibrary.org/obo/IEV_0003658 Circulatory system process The flow of blood through the body of an animal, enabling the transport of O2 and nutrients to the tissues and the removal of waste products. http://purl.obolibrary.org/obo/IEV_0000104 Cell migration http://purl.obolibrary.org/obo/IEV_0000103 Cell motion The orderly movement of cells from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/IEV_0001361 Activation of c-Raf1 by PKC alpha in cytosol http://purl.obolibrary.org/obo/IEV_0002485 Activation of Raf-1 by PKC in cytosol cPKCs (a and b1) have the potential to activate c-Raf1 in vivo while at the same time blocking further activation by growth factors and other PKC isotypes. http://purl.obolibrary.org/obo/IEV_0003814 Nucleobase, nucleoside, nucleotide and nucleic acid metabolism http://purl.obolibrary.org/obo/IEV_0000818 Metabolic pathway The chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0002721 enzymatic reaction EC:5 catalyzed process http://purl.obolibrary.org/obo/IEV_0001425 Glyoxylate and dicarboxylate metabolism http://purl.obolibrary.org/obo/IEV_0003810 Carboxylic acid metabolism Glyoxylate metabolism: The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH. Dicarboxylate metabolism: The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/IEV_0001257 PDGF receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0000830 RTK signaling pathway The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands. http://purl.obolibrary.org/obo/IEV_0003916 Glial cell differentiation http://purl.obolibrary.org/obo/IEV_0000002 Cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a glial cell. http://purl.obolibrary.org/obo/IEV_0001460 Tyrosine metabolism http://purl.obolibrary.org/obo/IEV_0001556 Amino Acid Metabolism The chemical reactions and pathways involving tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid. http://purl.obolibrary.org/obo/IEV_0001090 Binding of p27 and Cdk2 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus Involved in G1 arrest. May mediate TGF beta-induced G1 arrest. Binds to and inhibits complexes formed by cyclin E-CDK2, cyclin A-CDK2, and cyclin D1-CDK4. Interaction with nucleoporin NUP50 is required for nuclear import and for degradation of phosphorylated p27Kip1 after nuclear import. http://purl.obolibrary.org/obo/IEV_0001263 Ral mediated signaling http://purl.obolibrary.org/obo/IEV_0000676 Small GTPase mediated signaling A series of molecular signals within the cell that are mediated by a member of the Ral family of proteins switching to a GTP-bound active state. http://purl.obolibrary.org/obo/IEV_0000223 GDP-GTP exchange http://purl.obolibrary.org/obo/IEV_0000913 Transference GDP+ phosphate = GTP + H2O http://purl.obolibrary.org/obo/IEV_0000182 Gene expression http://purl.obolibrary.org/obo/IEV_0001886 Molecular interaction The process by which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/IEV_0000478 Phosphorylation of MAPK by MAPKK in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol The initiation of the activity of the inactive enzyme MAP kinase by phosphorylation by a MAPKK. http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway The processes by which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of cytokines to their cognate receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes. http://purl.obolibrary.org/obo/IEV_0001541 1,2-Dichloroethane degradation http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism The chemical reactions and pathways resulting in the breakdown of 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride. http://purl.obolibrary.org/obo/IEV_0003658 Circulatory system process http://purl.obolibrary.org/obo/IEV_0001327 Multicellular organismal process A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism. http://purl.obolibrary.org/obo/IEV_0003911 Endothelial cell differentiation http://purl.obolibrary.org/obo/IEV_0003910 Epithelial cell differentiation The process in which a mesodermal angioblast acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. http://purl.obolibrary.org/obo/IEV_0003918 Blood vessel morphogenesis http://purl.obolibrary.org/obo/IEV_0000447 Anatomical structure morphogenesis The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood. http://purl.obolibrary.org/obo/IEV_0003746 Larval development http://purl.obolibrary.org/obo/IEV_0000398 Post embryonic development The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of any animal when more or less of a metamorphosis takes place, before the assumption of the mature shape. http://purl.obolibrary.org/obo/IEV_0003702 Phosphorylation of transcriptional regulator by MAPK_p in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol Dually phosphorylated MAPK, or dpERK, phosphorylates protein targets in both the cytoplasm and nucleus. http://purl.obolibrary.org/obo/IEV_0003914 Epidermis development http://purl.obolibrary.org/obo/IEV_0003796 Tissue development The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of a plant or animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. http://purl.obolibrary.org/obo/IEV_0000820 Phosphorylation of MEK1/2(MKK1/2) by Raf in cytosol http://purl.obolibrary.org/obo/IEV_0000475 Phosphorylation of MEK1/2(MKK1/2) by MAPKKK in cytosol PDGF signaling, Integrin signaling, G http://purl.obolibrary.org/obo/IEV_0000124 Integrin signaling pathway http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway Any series of molecular signals generated as a consequence of an integrin binding to one of its physiological ligands. http://purl.obolibrary.org/obo/IEV_0001422 Carbohydrate Metabolism http://purl.obolibrary.org/obo/IEV_0000818 Metabolic pathway The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. http://purl.obolibrary.org/obo/IEV_0000811 Phosphorylation of MKK4/7 by ASK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000227 Phosphorylation of MKK4/7 by MAPKKK in cytosol TNFR1 signaling http://purl.obolibrary.org/obo/IEV_0000118 SUMOylation http://purl.obolibrary.org/obo/IEV_0000912 Ligation Reversible reaction that create a covalent bond between a C-terminus G of an ubiquitine like sumo protein and a K residue of the target. http://purl.obolibrary.org/obo/IEV_0001351 Negative regulation of EGF receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0000835 Negative regulation of RTK signaling pathway Any process that stops, prevents or reduces the rate, frequency or extent of epidermal growth factor receptor signaling pathway activity. http://purl.obolibrary.org/obo/IEV_0001232 Androgen receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001231 Steroid receptor signaling pathway Any series of molecular signals generated as a consequence of an androgen binding to its receptor. http://purl.obolibrary.org/obo/IEV_0002702 Spinal Dysraphism http://purl.obolibrary.org/obo/IEV_0002700 Neural Tube Defect Congenital defects of closure of one or more vertebral arches, which may be associated with malformations of the spinal cord, nerve roots, congenital fibrous bands, lipomas, and congenital cysts. These malformations range from mild (e.g., SPINA BIFIDA OCCULTA) to severe, including rachischisis where there is complete failure of neural tube and spinal cord fusion, resulting in exposure of the spinal cord at the surface. Spinal dysraphism includes all forms of spina bifida. The open form is called SPINA BIFIDA CYSTICA and the closed form is SPINA BIFIDA OCCULTA. http://purl.obolibrary.org/obo/IEV_0001092 Binding of GADD45 and PCNA in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol Binds to proliferating cell nuclear antigen. Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. http://purl.obolibrary.org/obo/IEV_0002519 Cellular defense (Activated blood cell) http://purl.obolibrary.org/obo/IEV_0001337 Response to stress A defense response that is mediated by cells. http://purl.obolibrary.org/obo/IEV_0001423 Nucleotide sugars metabolism http://purl.obolibrary.org/obo/IEV_0003814 Nucleobase, nucleoside, nucleotide and nucleic acid metabolism The chemical reactions and pathways involving nucleotide-sugars, any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. http://purl.obolibrary.org/obo/IEV_0001375 Negative regulation of T cell receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001374 Regulation of T cell receptor signaling pathway Any process that stops, prevents or reduces the rate, frequency or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell. http://purl.obolibrary.org/obo/IEV_0000744 Neurological system process http://purl.obolibrary.org/obo/IEV_0001327 Multicellular organismal process The processes pertaining to the functions of the nervous system of an organism. http://purl.obolibrary.org/obo/IEV_0002682 genetic interaction http://purl.obolibrary.org/obo/IEV_0001886 Molecular interaction Functional relationship among genes revealed by the phenotype of cells carrying combined mutations of those genes. http://purl.obolibrary.org/obo/IEV_0001342 Wound healing http://purl.obolibrary.org/obo/IEV_0001341 Response to wounding The series of events that restore integrity to a damaged tissue, following an injury. http://purl.obolibrary.org/obo/IEV_0002677 Neddylation http://purl.obolibrary.org/obo/IEV_0000912 Ligation Reversible reaction that create a covalent bond between a Glycine residue of an ubiquitine like NEDD8 protein and a lysine residue of the target. http://purl.obolibrary.org/obo/IEV_0002399 Transacetylation http://purl.obolibrary.org/obo/IEV_0000913 Transference Reaction, that can affect K,C,A,D,E,Q,G,I,K,M,P,S,T,Y,V residues. http://purl.obolibrary.org/obo/IEV_0000715 Diarrhea http://purl.obolibrary.org/obo/IEV_0000714 Clinical presentation An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight. http://purl.obolibrary.org/obo/IEV_0000874 Negative regulation of TGF beta signaling pathway http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway Any process that stops, prevents or reduces the rate, frequency or extent of any TGFbeta receptor signaling pathway. http://purl.obolibrary.org/obo/IEV_0001556 Amino Acid Metabolism http://purl.obolibrary.org/obo/IEV_0003810 Carboxylic acid metabolism The chemical reactions and pathways involving amino acids, organic acids containing one or more amino substituents. http://purl.obolibrary.org/obo/IEV_0001542 Tetrachloroethene degradation http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism The chemical reactions and pathways resulting in the breakdown of tetrachloroethylene, a derivative of ethene with the hydrogen atoms replaced by chlorines. http://purl.obolibrary.org/obo/IEV_0001837 Negative regulation of gene expression http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/IEV_0001325 Cell morphogenesis http://purl.obolibrary.org/obo/IEV_0001320 Cellular component organization The developmental process by which the size or shape of a cell is generated and organized. Morphogenesis pertains to the creation of form. http://purl.obolibrary.org/obo/IEV_0001098 Dephosphorylation Cdk2 by Cdc25A in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol Functions as a dosage-dependent inducer in mitotic control. It is a tyrosine protein phosphatase required for progression of the cell cycle. It directly dephosphorylates CDC2 and activate its kinase activity. It also dephosphorylates CDK2 in complex with cyclin E, in vitro. http://purl.obolibrary.org/obo/IEV_0001424 Pyruvate metabolism http://purl.obolibrary.org/obo/IEV_0003810 Carboxylic acid metabolism The chemical reactions and pathways involving pyruvate, 2-oxopropanoate. http://purl.obolibrary.org/obo/IEV_0001376 Positive regulation of T cell receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway Any process that activates or increases the rate, frequency or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell. http://purl.obolibrary.org/obo/IEV_0000398 Post embryonic development http://purl.obolibrary.org/obo/IEV_0000083 Development The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development. http://purl.obolibrary.org/obo/IEV_0001463 Phenylalanine biosynthesis http://purl.obolibrary.org/obo/IEV_0001461 Phenylalanine metabolism L-phenylalanine biosynthesis: The chemical reactions and pathways resulting in the formation of L-phenylalanine, the levorotatory isomer of 2-amino-3-phenylpropanoic acid. http://purl.obolibrary.org/obo/IEV_0001558 Glycan Biosynthesis and Metabolism http://purl.obolibrary.org/obo/IEV_0001422 Carbohydrate Metabolism Glycan biosynthesis: The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages. Glycan metabolism: The chemical reactions and pathways involving polysaccharides, a polymer of more than 10 monosaccharide residues joined by glycosidic linkages. http://purl.obolibrary.org/obo/IEV_0001462 Tryptophan metabolism http://purl.obolibrary.org/obo/IEV_0001556 Amino Acid Metabolism The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid. http://purl.obolibrary.org/obo/IEV_0000772 Cytosolic calcium ion concentration elevation (through IP3 receptor) http://purl.obolibrary.org/obo/IEV_0001246 Cytosolic calcium ion concentration elevation Any process that increases the concentration of calcium ions in the cytosol during the process of G-protein signaling coupled to IP3 second messenger. http://purl.obolibrary.org/obo/IEV_0001167 Translocation from Golgi to plasma membrane http://purl.obolibrary.org/obo/IEV_0000009 Translocation The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis. http://purl.obolibrary.org/obo/IEV_0001268 Negative regulation of IKK-NF-kappaB signaling http://purl.obolibrary.org/obo/IEV_0001267 Regulation of IKK-NF-kappaB signaling Any process that stops, prevents or reduces the frequency, rate or extent of an I-kappaB kinase/NF-kappaB induced cascade. http://purl.obolibrary.org/obo/IEV_0000682 Positive regulation of small GTPase mediated signaling http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction. http://purl.obolibrary.org/obo/IEV_0000216 Nuclear import of NF-kappaB http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import The directed movement of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane. http://purl.obolibrary.org/obo/IEV_0000550 Regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway Any process that modulates the frequency, rate or extent of the JAK-STAT signaling pathway. http://purl.obolibrary.org/obo/IEV_0001411 Glutamate metabolism http://purl.obolibrary.org/obo/IEV_0001556 Amino Acid Metabolism The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid. http://purl.obolibrary.org/obo/IEV_0001438 Sulfur metabolism http://purl.obolibrary.org/obo/IEV_0001552 Energy Metabolism The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. http://purl.obolibrary.org/obo/IEV_0001310 Nuclear import of NF-AT http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import The directed movement of NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors, from the cytoplasm into the nucleus. NFAT proteins are dephosphorylated in the cytoplasm by activated calcineurin, which leads to their translocation across the nuclear membrane. http://purl.obolibrary.org/obo/IEV_0000012 Ubiquitination http://purl.obolibrary.org/obo/IEV_0000912 Ligation Reversible reaction that create a covalent bond between a C-terminus G of ubiquitin and a K residue of the target. http://purl.obolibrary.org/obo/IEV_0001089 Binding of p15 and Cdk4/6 in cytosol http://purl.obolibrary.org/obo/IEV_0001087 Binding of INK4 family and Cdk4/6 in cytosol Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest. http://purl.obolibrary.org/obo/IEV_0001363 Activation of c-Raf1 by PKC eta in cytosol http://purl.obolibrary.org/obo/IEV_0002485 Activation of Raf-1 by PKC in cytosol At the level of Raf, the kinase that phosphorylates MEK-1, the activation cascade diverges; while conventional and novel PKCs (isotypes a and h) are potent activators of c-Raf1, atypical PKC-z cannot increase c-Raf1 activity,stimulating MEK by an independent mechanism. http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0000913 Transference The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological polymer. Irreversible reaction that can affect A,G,M,F,P,C,R,N,Q,E,H,or K residues. http://purl.obolibrary.org/obo/IEV_0001501 Biosynthesis of ansamycins http://purl.obolibrary.org/obo/IEV_0003811 Alcohol metabolism The chemical reactions and pathways leading to the formation of ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity. http://purl.obolibrary.org/obo/IEV_0001083 Regulation of S phase http://purl.obolibrary.org/obo/IEV_0001403 Regulation of cell cycle process A cell cycle process that modulates the rate or extent of the progression through the S phase of the cell cycle. http://purl.obolibrary.org/obo/IEV_0000784 Phosphorylation of IKK complex by TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000250 Phosphorylation of IKK complex by MAPKKK in cytosol Toll-like receptor pathway http://purl.obolibrary.org/obo/IEV_0000469 Binding of PLC gamma and PIP3 in cytosol http://purl.obolibrary.org/obo/IEV_0000284 Binding of PLC and PIP3 in cytosol activation of PLC gamma, PLC gamma_SH2 or PH domain http://purl.obolibrary.org/obo/IEV_0000683 Negative regulation of small GTPase mediated signaling http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway Any process that stops, prevents or reduces the frequency, rate or extent of small GTPase mediated signal transduction. http://purl.obolibrary.org/obo/IEV_0001353 Tyrosine biosynthesis http://purl.obolibrary.org/obo/IEV_0001460 Tyrosine metabolism The chemical reactions and pathways resulting in the formation of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid. http://purl.obolibrary.org/obo/IEV_0000103 Cell motion http://purl.obolibrary.org/obo/IEV_0000069 Cellular event Any process involved in the controlled movement of a cell. http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0000913 Transference Reversible reaction that can affect D,C,H,S,T,Y,R residues. http://purl.obolibrary.org/obo/IEV_0001327 Multicellular organismal process http://purl.obolibrary.org/obo/IEV_0001330 Physiological event Any biological process, occurring at the level of a multicellular organism, pertinent to its function. http://purl.obolibrary.org/obo/IEV_0000011 Dephosphorylation http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis Phosphoresidues are cleaved and return D,C,H,S,T,Y or R residues. http://purl.obolibrary.org/obo/IEV_0000368 G2-M-phase transition http://purl.obolibrary.org/obo/IEV_0000366 Cell cycle process Progression from G2 phase to M phase of the mitotic cell cycle. http://purl.obolibrary.org/obo/IEV_0000048 Nuclear import of STAT dimer http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import The transport of dimerized STAT (Signal Transducers and Activators of Transcription) proteins into the nucleus following activation by members of the janus activated kinase (JAK) family of tyrosine kinases. http://purl.obolibrary.org/obo/IEV_0001094 Binding of p19 and Cdk4/6 in cytosol http://purl.obolibrary.org/obo/IEV_0001087 Binding of INK4 family and Cdk4/6 in cytosol Interacts strongly with CDK4 and CDK6. http://purl.obolibrary.org/obo/IEV_0001546 Ethylbenzene degradation http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism The chemical reactions and pathways resulting in the breakdown of ethylbenzene, a benzene derivative with an ethyl group attached to the ring, which occurs in the absence of oxygen. http://purl.obolibrary.org/obo/IEV_0001731 Binding of 14-3-3 and HDAC5 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001698 Binding of 14-3-3 and HDAC5/7 in cytosol and/or nucleus CaMK-mediated nuclear export of HDAC5 appears to require binding of 14-3-3 to Ser-259 and Ser-498 in its amino terminus. Indeed, substitution of these serines with alanines blocks both 14-3-3 binding and nuclear export of HDAC5. However, association with 14-3-3 alone is not sufficient to localize HDAC5 in the cytoplasm, since NES mutants of HDAC5 associate with 14-3-3 in a CaMK-dependent manner but remain in the nucleus. http://purl.obolibrary.org/obo/IEV_0001091 Binding of p21 and Cdk2 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. May bind to and inhibit cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. http://purl.obolibrary.org/obo/IEV_0001324 Actin filament organization http://purl.obolibrary.org/obo/IEV_0001323 Actin cytoskeleton organization and biogenesis Control of the spatial distribution of actin filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking. http://purl.obolibrary.org/obo/IEV_0001465 beta-Alanine metabolism http://purl.obolibrary.org/obo/IEV_0001556 Amino Acid Metabolism The chemical reactions and pathways involving beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins. http://purl.obolibrary.org/obo/IEV_0003749 Ovulation http://purl.obolibrary.org/obo/IEV_0003747 Reproductive process in a multicellular organism The release of a mature ovum/oocyte from an ovary. http://purl.obolibrary.org/obo/IEV_0000085 Myoblast differentiation http://purl.obolibrary.org/obo/IEV_0000002 Cell differentiation The process whereby a relatively unspecialized cell acquires specialized features of a myoblast, a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/IEV_0002700 Neural Tube Defect http://purl.obolibrary.org/obo/IEV_0002699 Nervous System Malformation Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. http://purl.obolibrary.org/obo/IEV_0003872 T cell proliferation http://purl.obolibrary.org/obo/IEV_0001315 Lymphocyte proliferation The expansion of a T cell population by cell division. Follows T cell activation. http://purl.obolibrary.org/obo/IEV_0001170 Hydrolysis of Notch by Presenilin in plasma membrane http://purl.obolibrary.org/obo/IEV_0000269 Hydrolysis in plasma membrane within the transmembrane domain http://purl.obolibrary.org/obo/IEV_0000095 Stress fiber formation http://purl.obolibrary.org/obo/IEV_0001324 Actin filament organization Assembly of a stress fiber, the bundle of microfilaments and other proteins found in fibroblasts. http://purl.obolibrary.org/obo/IEV_0000918 Palmitoylation http://purl.obolibrary.org/obo/IEV_0002681 lipid addition Reversible reaction that can affect C,K,T or S residues. http://purl.obolibrary.org/obo/IEV_0001450 Purine metabolism http://purl.obolibrary.org/obo/IEV_0001554 Nucleotide Metabolism The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety. http://purl.obolibrary.org/obo/IEV_0001070 G1-S-phase transition http://purl.obolibrary.org/obo/IEV_0000366 Cell cycle process Progression from G1 phase to S phase of the mitotic cell cycle. http://purl.obolibrary.org/obo/IEV_0000445 MAPKKK cascade http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway Cascade of at least three protein kinase activities culminating in the phosphorylation and activation of a MAP kinase. MAPKKK cascades lie downstream of numerous signaling pathways. http://purl.obolibrary.org/obo/IEV_0002708 Neural tube closure http://purl.obolibrary.org/obo/IEV_0002704 Morphogenesis of embryonic epithelium The last step in the formation of the neural tube, where the paired neural folds are brought together at the dorsal midline. http://purl.obolibrary.org/obo/IEV_0003779 Autocleavage and cholesterol modification of Hedgehog in ER http://purl.obolibrary.org/obo/IEV_0003780 Hedgehog cleavage and lipidation It is further processed by internal cleavage to generate a 19-kDa N-terminal fragment (N-Hh) and a 25-kDa C-terminal fragment (C-Hh) with the concomitant addition of cholesterol at the C-terminus of N-Hh (N-Hhchol). http://purl.obolibrary.org/obo/IEV_0001473 Glutathione metabolism http://purl.obolibrary.org/obo/IEV_0001438 Sulfur metabolism The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism http://purl.obolibrary.org/obo/IEV_0000818 Metabolic pathway Xenobiotic degradation: The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide. Xenobiotic metabolism: The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide. http://purl.obolibrary.org/obo/IEV_0001100 Phosphorylation of Cdk2 by Cdk7 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive carboxyl-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. http://purl.obolibrary.org/obo/IEV_0000106 Behavior http://purl.obolibrary.org/obo/IEV_0001332 Response to stimulus The specific actions or reactions of an organism in response to external or internal stimuli. Patterned activity of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions. http://purl.obolibrary.org/obo/IEV_0001315 Lymphocyte proliferation http://purl.obolibrary.org/obo/IEV_0000076 Cell proliferation The rapid expansion of a lymphocyte population by cell division. http://purl.obolibrary.org/obo/IEV_0001415 Citrate cycle (TCA cycle) http://purl.obolibrary.org/obo/IEV_0001555 Metabolism of Cofactors and Vitamins A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two C02 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle. http://purl.obolibrary.org/obo/IEV_0003806 Neurotransmitter transport http://purl.obolibrary.org/obo/IEV_0000009 Translocation The directed movement of a neurotransmitter into, out of, within or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway Any process that stops, prevents or reduces the frequency, rate or extent of a signaling pathway. http://purl.obolibrary.org/obo/IEV_0000940 Apoptotic factor activation signaling http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling The conversion of proteins that induce or sustain apoptosis to an active form. http://purl.obolibrary.org/obo/IEV_0002571 Cleavage http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis Covalent bond breakage in a molecule leading to the formation of smaller molecules. http://purl.obolibrary.org/obo/IEV_0003804 receptor clustering http://purl.obolibrary.org/obo/IEV_0002524 Clustering Grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response. http://purl.obolibrary.org/obo/IEV_0001532 Puromycin biosynthesis http://purl.obolibrary.org/obo/IEV_0003814 Nucleobase, nucleoside, nucleotide and nucleic acid metabolism The chemical reactions and pathways resulting in the formation of puromycin, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger. http://purl.obolibrary.org/obo/IEV_0002663 Disulfide binding http://purl.obolibrary.org/obo/IEV_0002661 Covalent binding Covalent bond mediated by 2 sulfur atoms. http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway Any process that activates or increases the frequency, rate or extent of a signaling pathway. http://purl.obolibrary.org/obo/IEV_0001421 Aminosugars metabolism http://purl.obolibrary.org/obo/IEV_0003811 Alcohol metabolism The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group. http://purl.obolibrary.org/obo/IEV_0002675 Amidation http://purl.obolibrary.org/obo/IEV_0000912 Ligation Irreversible reaction that can affect A,R,N,D,C,Q,E,G,H,I,L,K,M,F,P,S,T,W,Y or V residues. http://purl.obolibrary.org/obo/IEV_0002678 Deneddylation http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis Cleavage of the G-K bond and release of the NEDD8 ubiquitin like proteins. Deneddylation, which removes the NEDD8 moiety, requires the isopeptidase activity of the COP9 signalosome. http://purl.obolibrary.org/obo/IEV_0002540 Endoderm development http://purl.obolibrary.org/obo/IEV_0003796 Tissue development The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues. http://purl.obolibrary.org/obo/IEV_0001520 Limonene and pinene degradation http://purl.obolibrary.org/obo/IEV_0001553 Lipid Metabolism Limonene degradation: The chemical reactions and pathways resulting in the breakdown of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene. alpha-pinene degradation: The chemical reactions and pathways resulting in the breakdown of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. http://purl.obolibrary.org/obo/IEV_0001699 AKT signaling http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B, which occurs as a result of a single trigger reaction or compound. http://purl.obolibrary.org/obo/IEV_0001521 Diterpenoid biosynthesis http://purl.obolibrary.org/obo/IEV_0001518 Terpenoid biosynthesis The chemical reactions and pathways resulting in the formation of diterpenoid compounds, terpenoids with four isoprene units. http://purl.obolibrary.org/obo/IEV_0000070 Apoptosis (Inhibition of cell survival) http://purl.obolibrary.org/obo/IEV_0000101 Programmed cell death A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposition of phosphatidylserine. http://purl.obolibrary.org/obo/IEV_0000097 Cell death http://purl.obolibrary.org/obo/IEV_0000069 Cellular event The specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. http://purl.obolibrary.org/obo/IEV_0000141 Flower development http://purl.obolibrary.org/obo/IEV_0000398 Post embryonic development The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem. http://purl.obolibrary.org/obo/IEV_0001489 Keratan sulfate biosynthesis http://purl.obolibrary.org/obo/IEV_0001438 Sulfur metabolism The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues. http://purl.obolibrary.org/obo/IEV_0003871 B cell proliferation http://purl.obolibrary.org/obo/IEV_0001315 Lymphocyte proliferation The expansion of a B cell population by cell division. Follows B cell activation. http://purl.obolibrary.org/obo/IEV_0000487 Insulin receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0003684 Insulin receptor family signaling pathway The series of molecular signals generated as a consequence of the insulin receptor binding to insulin. http://purl.obolibrary.org/obo/IEV_0001554 Nucleotide Metabolism http://purl.obolibrary.org/obo/IEV_0003814 Nucleobase, nucleoside, nucleotide and nucleic acid metabolism The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates). http://purl.obolibrary.org/obo/IEV_0001553 Lipid Metabolism http://purl.obolibrary.org/obo/IEV_0000818 Metabolic pathway The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. http://purl.obolibrary.org/obo/IEV_0000183 Transcription http://purl.obolibrary.org/obo/IEV_0001886 Molecular interaction The synthesis of either RNA on a template of DNA or DNA on a template of RNA. http://purl.obolibrary.org/obo/IEV_0001448 Glycerophospholipid metabolism http://purl.obolibrary.org/obo/IEV_0001447 Glycerolipid metabolism The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue. http://purl.obolibrary.org/obo/IEV_0001328 Rhythmic behavior http://purl.obolibrary.org/obo/IEV_0000106 Behavior The specific actions or reactions of an organism that recur with measured regularity. http://purl.obolibrary.org/obo/IEV_0001675 Regulation of Wnt signaling pathway http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway Any process that modulates the frequency, rate or extent of the activity of the Wnt receptor mediated signal transduction pathway. http://purl.obolibrary.org/obo/IEV_0001349 Phosphorylation of EGFR by PKC in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol PKC then phosphorylates and regulates the activity of many proteins, including EGFR; phosphorylation of a threonine residue (Thr654) in the juxtamembrane domain modulates EGF binding affinity and kinase activity of the EGFR. http://purl.obolibrary.org/obo/IEV_0001516 Porphyrin and chlorophyll metabolism http://purl.obolibrary.org/obo/IEV_0001555 Metabolism of Cofactors and Vitamins Porphyrin metabolism: The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group. Chlorophyll metabolism: The chemical reactions and pathways involving chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment. http://purl.obolibrary.org/obo/IEV_0001347 Binding of IL-12 and IL-12 receptor and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0000045 Binding of cytokine and cytokine receptors and conformational change of receptors in plasma membrane Combining with interleukin-12 to initiate a change in cell activity. http://purl.obolibrary.org/obo/IEV_0000621 Binding of FAK and PI3K in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol PI3K approaching to the plasma membrane http://purl.obolibrary.org/obo/IEV_0001180 Positive regulation of Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway Any process that activates or increases the rate, frequency or extent of the Notch signaling pathway. http://purl.obolibrary.org/obo/IEV_0001314 Lymphocyte differentiation http://purl.obolibrary.org/obo/IEV_0000002 Cell differentiation The process whereby a relatively unspecialized precursor cell acquires specialized features of B-cells, T-cells, or natural killer cells. http://purl.obolibrary.org/obo/IEV_0003795 Anatomical structure development http://purl.obolibrary.org/obo/IEV_0000083 Development The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. http://purl.obolibrary.org/obo/IEV_0003796 Tissue development http://purl.obolibrary.org/obo/IEV_0003795 Anatomical structure development The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/IEV_0000164 Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell. http://purl.obolibrary.org/obo/IEV_0000010 Proteasome degradation http://purl.obolibrary.org/obo/IEV_0003710 Degradation Cleavage of peptide bonds with very broad specificity. http://purl.obolibrary.org/obo/IEV_0001267 Regulation of IKK-NF-kappaB signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway Any process that modulates an I-kappaB kinase/NF-kappaB induced cascade. http://purl.obolibrary.org/obo/IEV_0001341 Response to wounding http://purl.obolibrary.org/obo/IEV_0001336 Response to external stimulus A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of damage to the organism. http://purl.obolibrary.org/obo/IEV_0001332 Response to stimulus http://purl.obolibrary.org/obo/IEV_0001330 Physiological event A change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the perception of a stimulus. http://purl.obolibrary.org/obo/IEV_0001456 Lysine biosynthesis http://purl.obolibrary.org/obo/IEV_0001556 Amino Acid Metabolism The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid. http://purl.obolibrary.org/obo/IEV_0002712 Organ development http://purl.obolibrary.org/obo/IEV_0003795 Anatomical structure development Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/IEV_0000121 Rhodopsin mediated signaling pathway http://purl.obolibrary.org/obo/IEV_0000661 GPCR signaling pathway The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon. http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0002721 enzymatic reaction EC:4 catalyzed process [STKE:0456] Enzyme that catalyzes the cleavage of C-C, C-O, C-S, C-N or other bonds by other means than by hydrolysis or oxidation, with two substrates in one reaction direction, and one in the other. In the latter direction, a molecule (of carbon dioxide, water, etc) is eliminated, thus creating a new double bond or a new ring. [GO:0016829] Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring. http://purl.obolibrary.org/obo/IEV_0001466 Methionine and Cysteine metabolism http://purl.obolibrary.org/obo/IEV_0001438 Sulfur metabolism Methionine metabolism: The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins. Cysteine metabolism: The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid. http://purl.obolibrary.org/obo/IEV_0001840 Positive regulation of translation http://purl.obolibrary.org/obo/IEV_0001841 Regulation of translation Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA. http://purl.obolibrary.org/obo/IEV_0002666 lipid cleavage http://purl.obolibrary.org/obo/IEV_0002571 Cleavage Cleavage of a lipid group covalently bound to a protein residue. http://purl.obolibrary.org/obo/IEV_0002664 Transglutamination http://purl.obolibrary.org/obo/IEV_0002661 Covalent binding Gln-Lys cross-link catalyzed by a transglutaminase. http://purl.obolibrary.org/obo/IEV_0002673 Deglycosylation http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis Reaction catalyzed by PNGase, a deglycosylating enzyme that promotes the hydrolysis of the beta-aspartylglycosylamine bond of aspargine-linked glycopeptides and glycoproteins. http://purl.obolibrary.org/obo/IEV_0003811 Alcohol metabolism http://purl.obolibrary.org/obo/IEV_0000818 Metabolic pathway The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. http://purl.obolibrary.org/obo/IEV_0001544 1,4-Dichlorobenzene degradation http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism The chemical reactions and pathways resulting in the breakdown of 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring. http://purl.obolibrary.org/obo/IEV_0000448 Hematopoiesis http://purl.obolibrary.org/obo/IEV_0002712 Organ development The process of blood cell formation. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates. http://purl.obolibrary.org/obo/IEV_0000462 Toll-like receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway Any series of molecular signals generated as a consequence of binding to a toll-like receptor. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response. http://purl.obolibrary.org/obo/IEV_0000574 Embryonic morphogenesis http://purl.obolibrary.org/obo/IEV_0000447 Anatomical structure morphogenesis The developmental processes by which defined structures within an embryo are generated. http://purl.obolibrary.org/obo/IEV_0000576 Organ morphogenesis http://purl.obolibrary.org/obo/IEV_0000447 Anatomical structure morphogenesis Morphogenesis of a tissue or tissues that function together to perform a specific function. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function. http://purl.obolibrary.org/obo/IEV_0001439 Fatty acid biosynthesis http://purl.obolibrary.org/obo/IEV_0001441 Fatty acid metabolism The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes. http://purl.obolibrary.org/obo/IEV_0000529 Phosphorylation of PLC gamma1 by Itk in cytosol http://purl.obolibrary.org/obo/IEV_0000286 Phosphorylation of PLC gamma by non-receptor tyrosine kinase in cytosol T-cell http://purl.obolibrary.org/obo/IEV_0001457 Lysine degradation http://purl.obolibrary.org/obo/IEV_0001556 Amino Acid Metabolism The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid. http://purl.obolibrary.org/obo/IEV_0001335 Response to endogenous stimulus http://purl.obolibrary.org/obo/IEV_0001332 Response to stimulus A change in state or activity of a cell or an organism as a result of the perception of an endogenous stimulus. http://purl.obolibrary.org/obo/IEV_0003744 Vulval development http://purl.obolibrary.org/obo/IEV_0002712 Organ development The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult. http://purl.obolibrary.org/obo/IEV_0000313 BME medium http://purl.obolibrary.org/obo/IEV_0000312 HeLa medium http://purl.obolibrary.org/obo/IEV_0000350 Waymouth's medium http://purl.obolibrary.org/obo/IEV_0000314 Mouse L-cell medium http://purl.obolibrary.org/obo/IEV_0003876 Th1 cell differentiation http://purl.obolibrary.org/obo/IEV_0003875 T cell differentiation http://purl.obolibrary.org/obo/IEV_0003877 Th2 cell differentiation http://purl.obolibrary.org/obo/IEV_0003875 T cell differentiation http://purl.obolibrary.org/obo/IEV_0000999 Binding of SMAC and XIAP:Caspase7 in cytosol http://purl.obolibrary.org/obo/IEV_0000995 Binding of SMAC and IAP in cytosol http://purl.obolibrary.org/obo/IEV_0001000 Binding of SMAC and XIAP:Caspase9 in cytosol http://purl.obolibrary.org/obo/IEV_0000995 Binding of SMAC and IAP in cytosol http://purl.obolibrary.org/obo/IEV_0000998 Binding of SMAC and XIAP:Caspase3 in cytosol http://purl.obolibrary.org/obo/IEV_0000995 Binding of SMAC and IAP in cytosol http://purl.obolibrary.org/obo/IEV_0000878 Positive regulation of TGF beta super family signaling pathway (through p38 cascade) http://purl.obolibrary.org/obo/IEV_0000876 Regulation of TGF beta super family signaling pathway (through p38 cascade) http://purl.obolibrary.org/obo/IEV_0002190 Positive regulation of (transcription by R-Smad:Smad4 ) in TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0000881 Positive regulation of TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0002624 Binding of EGFR and Shc in cytosol http://purl.obolibrary.org/obo/IEV_0000845 Binding of RTK and Shc in cytosol http://purl.obolibrary.org/obo/IEV_0002628 Binding of Met_p and Shc in cytosol http://purl.obolibrary.org/obo/IEV_0000845 Binding of RTK and Shc in cytosol http://purl.obolibrary.org/obo/IEV_0002629 Binding of TRK and Shc in cytosol http://purl.obolibrary.org/obo/IEV_0000845 Binding of RTK and Shc in cytosol http://purl.obolibrary.org/obo/IEV_0003553 Binding of IGF-1 receptor_p and Shc in cytosol http://purl.obolibrary.org/obo/IEV_0000845 Binding of RTK and Shc in cytosol http://purl.obolibrary.org/obo/IEV_0000816 Binding of PDGF receptor and Shc in cytosol http://purl.obolibrary.org/obo/IEV_0000845 Binding of RTK and Shc in cytosol http://purl.obolibrary.org/obo/IEV_0001264 I-kappaB degradation signaling http://purl.obolibrary.org/obo/IEV_0000122 Proteasome mediated protein degradation signaling http://purl.obolibrary.org/obo/IEV_0000901 Transcription of I-Smad by R-Smad:Smad4 in nucleus http://purl.obolibrary.org/obo/IEV_0000155 Transcription by R-Smad:Smad4 in nucleus http://purl.obolibrary.org/obo/IEV_0002224 Gene expression of SOCS3 by STAT dimer http://purl.obolibrary.org/obo/IEV_0002101 Gene expression of SOCS by STAT dimer http://purl.obolibrary.org/obo/IEV_0002238 Gene expression of SOCS1 by STAT dimer http://purl.obolibrary.org/obo/IEV_0002101 Gene expression of SOCS by STAT dimer http://purl.obolibrary.org/obo/IEV_0000703 Ras-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0000840 Negative regulation of PDGF signaling pathway (through Grb2, Sos, Ras, PI3K, AKT and IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0001043 Dissociation in ER membrane http://purl.obolibrary.org/obo/IEV_0001034 Dissociation in ER http://purl.obolibrary.org/obo/IEV_0001044 Dissociation in inner space of ER http://purl.obolibrary.org/obo/IEV_0001034 Dissociation in ER http://purl.obolibrary.org/obo/IEV_0000799 Negative regulation of PPAR signaling http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000800 Positive regulation of PPAR signaling http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000546 Regulation of G1-S-phase transition http://purl.obolibrary.org/obo/IEV_0001403 Regulation of cell cycle process http://purl.obolibrary.org/obo/IEV_0000512 Negative regulation of CD4 T cell receptor signaling (through PLC gamma, PKC and IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0001375 Negative regulation of T cell receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0000543 Positive regulation of CD4 T cell receptor signaling (through PLC gamma, PKC and IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0001376 Positive regulation of T cell receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001291 Binding of tyrosine-phosphorylated protein and PLC gamma in cytosol http://purl.obolibrary.org/obo/IEV_0001287 Binding of tyrosine-phosphorylated protein and PLC in cytosol http://purl.obolibrary.org/obo/IEV_0002193 Phosphorylation of Smad1 by MAPK in cytosol http://purl.obolibrary.org/obo/IEV_0000888 Phosphorylation of R-Smad:Smad4 by MAPK in cytosol http://purl.obolibrary.org/obo/IEV_0001117 Transcription of GADD45 by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0001144 Transcription by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0001120 Transcription of Mdm2 by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0001144 Transcription by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0001661 Transcription of apoptotic factor by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0001144 Transcription by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0001126 Transcription of p21 by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0001144 Transcription by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0003594 Binding of TGF beta superfamily and TGF beta superfamily receptor II in extracellular http://purl.obolibrary.org/obo/IEV_0000154 Binding of TGF beta superfamily and TGF beta superfamily receptor I/II in extracellular http://purl.obolibrary.org/obo/IEV_0003573 Binding of BMP and BMP receptor I/II in extracellular http://purl.obolibrary.org/obo/IEV_0000154 Binding of TGF beta superfamily and TGF beta superfamily receptor I/II in extracellular http://purl.obolibrary.org/obo/IEV_0000441 Lignin biosynthesis (angiosperm) http://purl.obolibrary.org/obo/IEV_0000396 Lignin biosynthesis http://purl.obolibrary.org/obo/IEV_0000442 Lignin biosynthesis (gymnosperm) http://purl.obolibrary.org/obo/IEV_0000396 Lignin biosynthesis http://purl.obolibrary.org/obo/IEV_0000443 Lignin biosynthesis (grasses) http://purl.obolibrary.org/obo/IEV_0000396 Lignin biosynthesis http://purl.obolibrary.org/obo/IEV_0000384 Magnetic force treatment http://purl.obolibrary.org/obo/IEV_0000380 Physical stimulus treatment http://purl.obolibrary.org/obo/IEV_0000385 Electricity treatment http://purl.obolibrary.org/obo/IEV_0000380 Physical stimulus treatment http://purl.obolibrary.org/obo/IEV_0000383 Contact pressure treatment http://purl.obolibrary.org/obo/IEV_0000380 Physical stimulus treatment http://purl.obolibrary.org/obo/IEV_0000381 Gravity treatment http://purl.obolibrary.org/obo/IEV_0000380 Physical stimulus treatment http://purl.obolibrary.org/obo/IEV_0002436 Phosphorylation of c-Jun by JNK1_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000230 Phosphorylation of c-Jun by JNK_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002441 Dimerization of EGFR in plasma membrane http://purl.obolibrary.org/obo/IEV_0000846 Dimerization of RTK in plasma membrane http://purl.obolibrary.org/obo/IEV_0002454 Dimerization of Met in plasma membrane http://purl.obolibrary.org/obo/IEV_0000846 Dimerization of RTK in plasma membrane http://purl.obolibrary.org/obo/IEV_0002471 Dimerization of TRK in plasma membrane http://purl.obolibrary.org/obo/IEV_0000846 Dimerization of RTK in plasma membrane http://purl.obolibrary.org/obo/IEV_0002479 Dimerization of KDR in plasma membrane http://purl.obolibrary.org/obo/IEV_0000846 Dimerization of RTK in plasma membrane http://purl.obolibrary.org/obo/IEV_0002487 Dimerization of FGFR in plasma membrane http://purl.obolibrary.org/obo/IEV_0000846 Dimerization of RTK in plasma membrane http://purl.obolibrary.org/obo/IEV_0000813 Dimerization of PDGF receptor in plasma membrane http://purl.obolibrary.org/obo/IEV_0000846 Dimerization of RTK in plasma membrane http://purl.obolibrary.org/obo/IEV_0001576 Sorbitol treatment http://purl.obolibrary.org/obo/IEV_0000064 Organic chemical treatment http://purl.obolibrary.org/obo/IEV_0001583 Sucrose treatment http://purl.obolibrary.org/obo/IEV_0001581 Carbohydrate treatment http://purl.obolibrary.org/obo/IEV_0001585 Glucose treatment http://purl.obolibrary.org/obo/IEV_0001581 Carbohydrate treatment http://purl.obolibrary.org/obo/IEV_0001584 Fructose treatment http://purl.obolibrary.org/obo/IEV_0001581 Carbohydrate treatment http://purl.obolibrary.org/obo/IEV_0001582 Hexose treatment http://purl.obolibrary.org/obo/IEV_0001581 Carbohydrate treatment http://purl.obolibrary.org/obo/IEV_0001785 Binding of Androgen receptor and PIAS4 in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0001730 Binding in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0001698 Binding of 14-3-3 and HDAC5/7 in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0001730 Binding in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001730 Binding in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0000015 Binding in nucleus http://purl.obolibrary.org/obo/IEV_0001730 Binding in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0001831 Sumoylation of trans-activator by PIAS in nucleus http://purl.obolibrary.org/obo/IEV_0001829 SUMOylation in nucleus http://purl.obolibrary.org/obo/IEV_0001366 Hydrolysis of PIP2 by PLC gamma1 to generate DAG and IP3 in cytosol http://purl.obolibrary.org/obo/IEV_0000268 Hydrolysis of PIP2 by PLC gamma to generate DAG and IP3 in cytosol http://purl.obolibrary.org/obo/IEV_0001262 Rho-PI5K signaling http://purl.obolibrary.org/obo/IEV_0001260 Rho mediated signaling http://purl.obolibrary.org/obo/IEV_0001261 Rho-p160-myosin phosphatase signaling http://purl.obolibrary.org/obo/IEV_0001260 Rho mediated signaling http://purl.obolibrary.org/obo/IEV_0001479 CD28 signaling http://purl.obolibrary.org/obo/IEV_0000543 Positive regulation of CD4 T cell receptor signaling (through PLC gamma, PKC and IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0002308 Phosphorylation of PLC gamma2 by Syk in cytosol http://purl.obolibrary.org/obo/IEV_0000530 Phosphorylation of PLC gamma by Syk in cytosol http://purl.obolibrary.org/obo/IEV_0003516 Transcription of cecropin by DIF in nucleus http://purl.obolibrary.org/obo/IEV_0003517 Transcription of antimicrobial peptide by DIF in nucleus http://purl.obolibrary.org/obo/IEV_0003519 Transcription of drosomycin by DIF in nucleus http://purl.obolibrary.org/obo/IEV_0003517 Transcription of antimicrobial peptide by DIF in nucleus http://purl.obolibrary.org/obo/IEV_0003520 Transcription of diptericin by DIF in nucleus http://purl.obolibrary.org/obo/IEV_0003517 Transcription of antimicrobial peptide by DIF in nucleus http://purl.obolibrary.org/obo/IEV_0003180 1D-myo-Inositol 3-phosphate + H2O => myo-Inositol + Orthophosphate( EC:3.1.3.25 ) http://purl.obolibrary.org/obo/IEV_0002750 myo-inositol phosphate + H2O = myo-inositol + Orthophosphate( EC:3.1.3.25 ) http://purl.obolibrary.org/obo/IEV_0002919 1D-myo-Inositol 1-phosphate + H2O => myo-Inositol + Orthophosphate( EC:3.1.3.25 ) http://purl.obolibrary.org/obo/IEV_0002750 myo-inositol phosphate + H2O = myo-inositol + Orthophosphate( EC:3.1.3.25 ) http://purl.obolibrary.org/obo/IEV_0002841 1D-myo-Inositol 4-phosphate + H2O => myo-Inositol + Orthophosphate( EC:3.1.3.25 ) http://purl.obolibrary.org/obo/IEV_0002750 myo-inositol phosphate + H2O = myo-inositol + Orthophosphate( EC:3.1.3.25 ) http://purl.obolibrary.org/obo/IEV_0002827 NAD+ + (S)-3-Hydroxy-butanoyl-CoA = NADH + Acetoacetyl-CoA + H+( EC:1.1.1.35 ) http://purl.obolibrary.org/obo/IEV_0002725 (3S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H+( EC:1.1.1.35 ) http://purl.obolibrary.org/obo/IEV_0002843 NAD+ + (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA = NADH + 2-Methyl-3-acetoacetyl-CoA + H+( EC:1.1.1.35 ) http://purl.obolibrary.org/obo/IEV_0002725 (3S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H+( EC:1.1.1.35 ) http://purl.obolibrary.org/obo/IEV_0002850 NAD+ + (S)-3-Hydroxyisobutyrate = NADH + (S)-Methyl-malonate semialdehyde + H+( EC:1.1.1.35 ) http://purl.obolibrary.org/obo/IEV_0002725 (3S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H+( EC:1.1.1.35 ) http://purl.obolibrary.org/obo/IEV_0003287 GTP + H2O => GMP + Pyrophosphate( EC:3.6.1.19 ) http://purl.obolibrary.org/obo/IEV_0002755 Nucleoside triphosphate + H2O = Nucleotide + diphosphate( EC:3.6.1.19 ) http://purl.obolibrary.org/obo/IEV_0002797 XTP + H2O => XMP + Pyrophosphate( EC:3.6.1.19 ) http://purl.obolibrary.org/obo/IEV_0002755 Nucleoside triphosphate + H2O = Nucleotide + diphosphate( EC:3.6.1.19 ) http://purl.obolibrary.org/obo/IEV_0002969 ITP + H2O => IMP + Pyrophosphate( EC:3.6.1.19 ) http://purl.obolibrary.org/obo/IEV_0002755 Nucleoside triphosphate + H2O = Nucleotide + diphosphate( EC:3.6.1.19 ) http://purl.obolibrary.org/obo/IEV_0003238 dGTP + H2O => dGMP + Pyrophosphate( EC:3.6.1.19 ) http://purl.obolibrary.org/obo/IEV_0002755 Nucleoside triphosphate + H2O = Nucleotide + diphosphate( EC:3.6.1.19 ) http://purl.obolibrary.org/obo/IEV_0003239 dITP + H2O => dIMP + Pyrophosphate( EC:3.6.1.19 ) http://purl.obolibrary.org/obo/IEV_0002755 Nucleoside triphosphate + H2O = Nucleotide + diphosphate( EC:3.6.1.19 ) http://purl.obolibrary.org/obo/IEV_0003187 dUTP + H2O => dUMP + Pyrophosphate( EC:3.6.1.19 ) http://purl.obolibrary.org/obo/IEV_0002755 Nucleoside triphosphate + H2O = Nucleotide + diphosphate( EC:3.6.1.19 ) http://purl.obolibrary.org/obo/IEV_0003042 UTP + H2O => UMP + Pyrophosphate( EC:3.6.1.19 ) http://purl.obolibrary.org/obo/IEV_0002755 Nucleoside triphosphate + H2O = Nucleotide + diphosphate( EC:3.6.1.19 ) http://purl.obolibrary.org/obo/IEV_0003404 Phosphorylation of Itch by JNK_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003403 Phosphorylation of transcriptional regulator by JNK_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003546 Negative feedback regulation of Ras-Raf-MAPK signaling by spred http://purl.obolibrary.org/obo/IEV_0003544 Negative regulation of Ras-Raf-MAPK signaling by spred http://purl.obolibrary.org/obo/IEV_0003547 Negative feedback regulation of Ras-Raf-MAPK signaling by Sprouty http://purl.obolibrary.org/obo/IEV_0003544 Negative regulation of Ras-Raf-MAPK signaling by spred http://purl.obolibrary.org/obo/IEV_0000244 Activation in plasma membrane http://purl.obolibrary.org/obo/IEV_0000008 Activation http://purl.obolibrary.org/obo/IEV_0000038 Activation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000008 Activation http://purl.obolibrary.org/obo/IEV_0000979 Activation in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000008 Activation http://purl.obolibrary.org/obo/IEV_0000725 Activation in extracellular http://purl.obolibrary.org/obo/IEV_0000008 Activation http://purl.obolibrary.org/obo/IEV_0002652 Activation in nucleus http://purl.obolibrary.org/obo/IEV_0000008 Activation http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0000008 Activation http://purl.obolibrary.org/obo/IEV_0003639 Phosphorylation of 4EBP-1 by TOR of TORC1 in cytosol http://purl.obolibrary.org/obo/IEV_0000061 Phosphorylation of 4EBP by TOR of TORC1 in cytosol http://purl.obolibrary.org/obo/IEV_0000542 Regulation of CD4 T cell receptor signaling (through PLC gamma, PKC and IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0001374 Regulation of T cell receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001796 Regulation of CD4 T cell receptor signaling (through PLC gamma, calcineurin and NF-AT) http://purl.obolibrary.org/obo/IEV_0001374 Regulation of T cell receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0002196 Regulation of CD4 T cell receptor signaling (through Ras Vav, Rac and JNK cascade) http://purl.obolibrary.org/obo/IEV_0001374 Regulation of T cell receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0002248 Regulation of CD4 T cell receptor signaling (through Ras and Erk cascade) http://purl.obolibrary.org/obo/IEV_0001374 Regulation of T cell receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0000843 Autophosphorylation of RTK in plasma membrane http://purl.obolibrary.org/obo/IEV_0000486 Autophosphorylation in plasma membrane http://purl.obolibrary.org/obo/IEV_0000489 Autophosphorylation of insulin receptor in plasma membrane http://purl.obolibrary.org/obo/IEV_0000486 Autophosphorylation in plasma membrane http://purl.obolibrary.org/obo/IEV_0001218 Binding of Transcription factor complex and pCAF in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001220 Binding of Transcription factor complex and HAT in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001216 Binding of Transcription factor complex and CBP in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001220 Binding of Transcription factor complex and HAT in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001219 Binding of Transcription factor complex and p300 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001220 Binding of Transcription factor complex and HAT in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001230 Binding of Estrogen and Estrogen receptor beta in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001201 Binding of Estrogen and Estrogen receptor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001229 Binding of Estrogen and Estrogen receptor alpha in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001201 Binding of Estrogen and Estrogen receptor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001569 Cyclohexemide medication http://purl.obolibrary.org/obo/IEV_0001567 Protein synthesis inhibitor medication http://purl.obolibrary.org/obo/IEV_0001587 Puromycin medication http://purl.obolibrary.org/obo/IEV_0001567 Protein synthesis inhibitor medication http://purl.obolibrary.org/obo/IEV_0001586 Anisomycin medication http://purl.obolibrary.org/obo/IEV_0001567 Protein synthesis inhibitor medication http://purl.obolibrary.org/obo/IEV_0000496 Dissociation of IRS and insulin receptor in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0000961 Dissociation of Bim and dynein:myosin V in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0000824 Dissociation of Ras-GDP and target protein in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0000852 Dissociation of Rac-GDP and target protein in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0000041 Dissociation of Axin, APC, GSK3beta, CK1alpha and beta-catenin in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0000215 Dissociation of NF-kappaB and I-kappaB in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0000493 Dissociation of Shc and insulin receptor in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0000664 Dissociation of G alpha-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0000764 Dissociation of cGMP and cGMP activated cation ion channel and the channel closing in cytosol http://purl.obolibrary.org/obo/IEV_0000762 Channel opening/closing in the plasma membrane http://purl.obolibrary.org/obo/IEV_0000965 Dissociation of Bmf and dynein:myosin V in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0001704 Dissociation of 14-3-3 and HDAC5/7 in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0001980 Dissociation of IRAK1_p and TRAF6 in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0002184 Dissociation of Smad7:smurf1 and TGF beta receptor complex_Ub in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0003530 Dissociation of Toll:MyD88:Tube and Pelle in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0003591 Dissociation of TGF beta superfamily receptor complex and R-Smad in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0003672 Dissociation of 4EBP and eIF4E in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0003767 Dissociation of Cos2:Fu:Ci/Gli and PKA, GSK3, CK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0003771 Dissociation of Sufu and Ci/Gli in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0003772 Dissociation of Ci/Gli and Smo:Cos2:Fu in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0003870 Dissociation of Axin, APC, GSK3beta and beta-catenin in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0003900 Dissociation of PDGF receptor and PLC gamma1 in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0001048 Dissociation outside the nuclear membrane http://purl.obolibrary.org/obo/IEV_0001047 Dissociation in nuclear membrane http://purl.obolibrary.org/obo/IEV_0003632 Dissociation of Ras-GTP and Raf in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0003385 Dissociation of TRAF6:TAK1:TAB1:TAB2 and IRAK in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0003408 Dissociation of 14-3-3_p and Bax in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0000894 Dissociation of Smad7:smurf2 and TGF beta receptor I_Ub in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0000898 Dissociation of Smad7:smurf1/2 and R-Smad_Ub in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0001032 Dissociation outside the ER membrane http://purl.obolibrary.org/obo/IEV_0001043 Dissociation in ER membrane http://purl.obolibrary.org/obo/IEV_0000933 Dissociation of TRADD:TRAF2:RIP complex and TNF alpha:TNFR1 in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0003901 Dissociation of PDGF receptor and STAT5 in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0001038 Dissociation outside the mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000950 Dissociation in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0003893 Dissociation of PAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0000997 Dissociation of Caspase and SMAC:IAP in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0000675 Dissociation of G alpha-GDP and target protein in cytosol http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0000499 Influx of hydrogen ion into the lumen of the endosome by proton pump http://purl.obolibrary.org/obo/IEV_0000504 Translocation from cytosol into lumen of endosome http://purl.obolibrary.org/obo/IEV_0003363 Translation of Sprouty1 in cytosol http://purl.obolibrary.org/obo/IEV_0003720 Translation of Sprouty in cytosol http://purl.obolibrary.org/obo/IEV_0003342 Translation of Sprouty2 in cytosol http://purl.obolibrary.org/obo/IEV_0003720 Translation of Sprouty in cytosol http://purl.obolibrary.org/obo/IEV_0002793 NAD+ + Phenyl-acetaldehyde + H2O = NADH + Phenyl-acetic acid + H+( EC:1.2.1.5 ) http://purl.obolibrary.org/obo/IEV_0002730 Aldehyde + NADP+ + H2O = Carboxylate + NADPH + H+( EC:1.2.1.5 ) http://purl.obolibrary.org/obo/IEV_0002848 NAD+ + Methylimidazole acetaldehyde + H2O = NADH + Methylimidazoleacetic acid + H+( EC:1.2.1.5 ) http://purl.obolibrary.org/obo/IEV_0002730 Aldehyde + NADP+ + H2O = Carboxylate + NADPH + H+( EC:1.2.1.5 ) http://purl.obolibrary.org/obo/IEV_0002949 NAD+ + 3-Methoxy-4-hydroxy-phenyl-glycolaldehyde + H2O = NADH + 3-Methoxy-4-hydroxy-mandelic acid + H+( EC:1.2.1.5 ) http://purl.obolibrary.org/obo/IEV_0002730 Aldehyde + NADP+ + H2O = Carboxylate + NADPH + H+( EC:1.2.1.5 ) http://purl.obolibrary.org/obo/IEV_0003052 NAD+ + 4-Hydroxy-phenyl-acetaldehyde + H2O = NADH + 4-Hydroxy-phenyl-acetic acid + H+( EC:1.2.1.5 ) http://purl.obolibrary.org/obo/IEV_0002730 Aldehyde + NADP+ + H2O = Carboxylate + NADPH + H+( EC:1.2.1.5 ) http://purl.obolibrary.org/obo/IEV_0003073 NAD+ + 3-Methoxy-4-hydroxy-phenyl-acetaldehyde + H2O = NADH + Homovanillic acid + H+( EC:1.2.1.5 ) http://purl.obolibrary.org/obo/IEV_0002730 Aldehyde + NADP+ + H2O = Carboxylate + NADPH + H+( EC:1.2.1.5 ) http://purl.obolibrary.org/obo/IEV_0003121 NAD+ + 3,4-Dihydroxy-mandelaldehyde + H2O = NADH + 3,4-Dihydroxy-mandelic acid + H+( EC:1.2.1.5 ) http://purl.obolibrary.org/obo/IEV_0002730 Aldehyde + NADP+ + H2O = Carboxylate + NADPH + H+( EC:1.2.1.5 ) http://purl.obolibrary.org/obo/IEV_0003153 NAD+ + 3,4-Dihydroxy-phenyl-acetaldehyde + H2O = NADH + 3,4-Dihydroxy-phenyl-acetic acid + H+( EC:1.2.1.5 ) http://purl.obolibrary.org/obo/IEV_0002730 Aldehyde + NADP+ + H2O = Carboxylate + NADPH + H+( EC:1.2.1.5 ) http://purl.obolibrary.org/obo/IEV_0003559 IGF1 signaling pathway http://purl.obolibrary.org/obo/IEV_0000454 IGF signaling pathway http://purl.obolibrary.org/obo/IEV_0002405 Binding of Group I mGlu receptor and G alpha q in cytosol http://purl.obolibrary.org/obo/IEV_0002064 Binding of GPCR and G alpha q in cytosol http://purl.obolibrary.org/obo/IEV_0003213 ATP + N-Acetyl-D-mannosamine => ADP + N-Acetyl-D-mannosamine 6-phosphate( EC:2.7.1.60 ) http://purl.obolibrary.org/obo/IEV_0002745 ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate( EC:2.7.1.60 ) http://purl.obolibrary.org/obo/IEV_0000504 Translocation from cytosol into lumen of endosome http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0000429 Translocation from cytosol to cell wall http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0000412 Translocation from cytosol to mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0000505 Translocation from endosome to plasma membrane http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0000508 Translocation from plasma membrane to cytosol http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0001203 Translocation from extracellular to cytosol http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0001251 Translocation from cytosol to extracellular http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0001386 Recruitment to the raft http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0001939 Translocation from ER to extracellular space http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0001941 Translocation from ER to plasma membrane http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0001942 Translocation from cytosol to plasma membrane http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0001943 Translocation from ER to cytosol http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0002614 Translocation from cytosol to Golgi http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0003716 Translocation from Golgi to extracellular http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0003755 Translocation into the cilia http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0003764 Translocation from plasma membrane to endosome http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0003837 Translocation out of the cilia http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0002612 Translocation from ER to Golgi http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0002545 Accumulation http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0003888 Translocation in extracellular http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0000985 Translocation from mitochondria to cytosol http://purl.obolibrary.org/obo/IEV_0000009 Translocation http://purl.obolibrary.org/obo/IEV_0002868 Melatonin + O2 + Reduced flavoprotein => 6-Hydroxy-melatonin + H2O + Oxidized flavoprotein( EC:1.14.14.1 ) http://purl.obolibrary.org/obo/IEV_0002727 Alkane + Reduced flavoprotein + O2 = ROH + Oxidized flavoprotein + H2O( EC:1.14.14.1 ) http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000185 Environmental event http://purl.obolibrary.org/obo/IEV_0000387 Treatment http://purl.obolibrary.org/obo/IEV_0000185 Environmental event http://purl.obolibrary.org/obo/IEV_0000299 BEBM (medium) http://purl.obolibrary.org/obo/IEV_0000352 Human bronchial epithelial cell medium http://purl.obolibrary.org/obo/IEV_0000355 SAGM (medium) http://purl.obolibrary.org/obo/IEV_0000352 Human bronchial epithelial cell medium http://purl.obolibrary.org/obo/IEV_0000356 BEGM (medium) http://purl.obolibrary.org/obo/IEV_0000352 Human bronchial epithelial cell medium http://purl.obolibrary.org/obo/IEV_0000300 SABM (medium) http://purl.obolibrary.org/obo/IEV_0000352 Human bronchial epithelial cell medium http://purl.obolibrary.org/obo/IEV_0003831 GDP-GTP exchange of Ras by Sos1 in cytosol http://purl.obolibrary.org/obo/IEV_0000604 GDP-GTP exchange of Ras by Sos in cytosol http://purl.obolibrary.org/obo/IEV_0000833 Rac activation signaling (through PI3K) http://purl.obolibrary.org/obo/IEV_0001300 Rac activation signaling http://purl.obolibrary.org/obo/IEV_0000522 Phosphorylation of CD3 zeta by Lck_p in cytosol http://purl.obolibrary.org/obo/IEV_0001253 Phosphorylation of CD3 zeta by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000523 Phosphorylation of CD3 zeta by Fyn_p in cytosol http://purl.obolibrary.org/obo/IEV_0001253 Phosphorylation of CD3 zeta by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000369 Binding of Cdk4 and cyclin D in cytosol http://purl.obolibrary.org/obo/IEV_0001071 Binding of Cdk4/6 and cyclin D in cytosol http://purl.obolibrary.org/obo/IEV_0001560 Biosynthesis of Secondary Metabolites http://purl.obolibrary.org/obo/IEV_0000818 Metabolic pathway http://purl.obolibrary.org/obo/IEV_0001552 Energy Metabolism http://purl.obolibrary.org/obo/IEV_0000818 Metabolic pathway http://purl.obolibrary.org/obo/IEV_0000815 Binding of PDGF receptor and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0000844 Binding of RTK and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0002458 Binding of Met_p and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0000844 Binding of RTK and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0002623 Binding of EGFR and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0000844 Binding of RTK and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0003800 Binding of FGFR and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0000844 Binding of RTK and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0002630 Binding of TRK and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0000844 Binding of RTK and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0000500 Dissociation of insulin and insulin receptor in extracellular http://purl.obolibrary.org/obo/IEV_0000506 Dissociation in extracellular http://purl.obolibrary.org/obo/IEV_0001632 Negative regulation of (dephosphorylation of Lck) Lck activation signaling (autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001617 Negative regulation of Lck activation signaling http://purl.obolibrary.org/obo/IEV_0001894 Negative regulation of (phosphorylation of Lck) Lck activation signaling (autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001896 Negative regulation of Lck activation signaling (autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001680 Deacetylation of Ku70 by SIRT1 in nucleus http://purl.obolibrary.org/obo/IEV_0001683 Deacetylation in nucleus http://purl.obolibrary.org/obo/IEV_0001876 Deacetylation of histone by HDAC5/7 in nucleus http://purl.obolibrary.org/obo/IEV_0001683 Deacetylation in nucleus http://purl.obolibrary.org/obo/IEV_0000192 Binding of MyD88 and IRAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000242 Binding of MyD88 and IRAK in cytosol http://purl.obolibrary.org/obo/IEV_0003501 Binding of Toll:MyD88:Tube and Pelle in cytosol http://purl.obolibrary.org/obo/IEV_0000242 Binding of MyD88 and IRAK in cytosol http://purl.obolibrary.org/obo/IEV_0000194 Binding of MyD88 and IRAK4 in cytosol http://purl.obolibrary.org/obo/IEV_0000242 Binding of MyD88 and IRAK in cytosol http://purl.obolibrary.org/obo/IEV_0000153 Cell survival (Inhibition of apoptosis) http://purl.obolibrary.org/obo/IEV_0000069 Cellular event http://purl.obolibrary.org/obo/IEV_0001600 Dephosphorylation of Src_p by SHP-1 and active conformational change http://purl.obolibrary.org/obo/IEV_0001638 Dephosphorylation of Src_p by PTP and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001601 Dephosphorylation of Src_p by SHP-2 and active conformational change http://purl.obolibrary.org/obo/IEV_0001638 Dephosphorylation of Src_p by PTP and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001646 Dephosphorylation of Src_p by PTP alpha and active conformational change http://purl.obolibrary.org/obo/IEV_0001638 Dephosphorylation of Src_p by PTP and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001647 Dephosphorylation of Src_p by PTP lambda and active conformational change http://purl.obolibrary.org/obo/IEV_0001638 Dephosphorylation of Src_p by PTP and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001648 Dephosphorylation of Src_p by PTP1B and active conformational change http://purl.obolibrary.org/obo/IEV_0001638 Dephosphorylation of Src_p by PTP and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0000245 Inactivation in extracellular http://purl.obolibrary.org/obo/IEV_0000007 Inactivation http://purl.obolibrary.org/obo/IEV_0003548 Inactivation in plasma membrane http://purl.obolibrary.org/obo/IEV_0000007 Inactivation http://purl.obolibrary.org/obo/IEV_0000967 Inactivation in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000007 Inactivation http://purl.obolibrary.org/obo/IEV_0000246 Inactivation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000007 Inactivation http://purl.obolibrary.org/obo/IEV_0000024 Inactivation in cytosol http://purl.obolibrary.org/obo/IEV_0000007 Inactivation http://purl.obolibrary.org/obo/IEV_0002795 Succinyl-CoA + Acetoacetic acid = Succinic acid + Acetoacetyl-CoA( EC:2.8.3.5 ) http://purl.obolibrary.org/obo/IEV_0002749 Succinyl-CoA + 3-oxo acid = succinate + 3-oxoacyl-CoA( EC:2.8.3.5 ) http://purl.obolibrary.org/obo/IEV_0000818 Metabolic pathway http://purl.obolibrary.org/obo/IEV_0000001 Pathway http://purl.obolibrary.org/obo/IEV_0000145 Regulation pathway http://purl.obolibrary.org/obo/IEV_0000001 Pathway http://purl.obolibrary.org/obo/IEV_0000120 TPO signaling pathway http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway http://purl.obolibrary.org/obo/IEV_0000090 TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway http://purl.obolibrary.org/obo/IEV_0000110 IL1 signaling pathway http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway http://purl.obolibrary.org/obo/IEV_0001863 Protein nuclear import/export signaling http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway http://purl.obolibrary.org/obo/IEV_0003809 Receptor recycling mediated signaling http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway http://purl.obolibrary.org/obo/IEV_0000128 Caspase Cascade http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway http://purl.obolibrary.org/obo/IEV_0000789 PPAR signaling http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway http://purl.obolibrary.org/obo/IEV_0003456 IMD signaling pathway http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway http://purl.obolibrary.org/obo/IEV_0000471 PLC signaling http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway http://purl.obolibrary.org/obo/IEV_0000465 TNFR signaling pathway http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway http://purl.obolibrary.org/obo/IEV_0000988 SMAC mediated signaling http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway http://purl.obolibrary.org/obo/IEV_0001686 Caloric restriction - cell survival signaling http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway http://purl.obolibrary.org/obo/IEV_0001103 p53 signaling pathway http://purl.obolibrary.org/obo/IEV_0001842 Signaling pathway http://purl.obolibrary.org/obo/IEV_0000684 Small GTPase hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0000683 Negative regulation of small GTPase mediated signaling http://purl.obolibrary.org/obo/IEV_0002243 Dephosphorylation of cytokine receptor by SHP-1 in cytosol http://purl.obolibrary.org/obo/IEV_0000147 Dephosphorylation of cytokine receptor by PTP in cytosol http://purl.obolibrary.org/obo/IEV_0002325 Dephosphorylation of GHR_p by SHP-2 in cytosol http://purl.obolibrary.org/obo/IEV_0001750 Negative regulation of Growth hormone signaling pathway (JAK2 STAT5) http://purl.obolibrary.org/obo/IEV_0002403 Binding of G alpha q-GTP and PLC in cytosol http://purl.obolibrary.org/obo/IEV_0002016 Binding of G alpha q-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0000755 Binding of G alpha q-GTP and RGS in cytosol http://purl.obolibrary.org/obo/IEV_0000674 Binding of G alpha-GTP and RGS in cytosol http://purl.obolibrary.org/obo/IEV_0000001 Pathway http://purl.obolibrary.org/obo/IEV_0000071 Molecular event http://purl.obolibrary.org/obo/IEV_0000767 Channel opening/closing http://purl.obolibrary.org/obo/IEV_0000071 Molecular event http://purl.obolibrary.org/obo/IEV_0001886 Molecular interaction http://purl.obolibrary.org/obo/IEV_0000071 Molecular event http://purl.obolibrary.org/obo/IEV_0000771 Change in material concentration http://purl.obolibrary.org/obo/IEV_0000071 Molecular event http://purl.obolibrary.org/obo/IEV_0001391 PKC theta activation signaling http://purl.obolibrary.org/obo/IEV_0000779 PKC activation signaling http://purl.obolibrary.org/obo/IEV_0002437 PKC delta activation signaling http://purl.obolibrary.org/obo/IEV_0000779 PKC activation signaling http://purl.obolibrary.org/obo/IEV_0001392 cPKC activation signaling http://purl.obolibrary.org/obo/IEV_0000779 PKC activation signaling http://purl.obolibrary.org/obo/IEV_0001930 Ubiquitination of Mdm4 by Mdm2 in nucleus http://purl.obolibrary.org/obo/IEV_0000871 Ubiquitination in nucleus http://purl.obolibrary.org/obo/IEV_0001932 Ubiquitination of p53 by ubiquitin ligase in nucleus http://purl.obolibrary.org/obo/IEV_0000871 Ubiquitination in nucleus http://purl.obolibrary.org/obo/IEV_0002887 L-Tryptophan + Tetrahydrobiopterin + O2 => 5-Hydroxy-L-tryptophan + 6,7-Dihydro-biopterin + H2O( EC:1.14.16.4 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002851 NADP+ + beta-D-Glucose = NADPH + D-Glucono-1,5-lactone + H+( EC:1.1.1.47 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002725 (3S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H+( EC:1.1.1.35 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002815 NAD+ + 4-Amino-butyraldehyde + H2O => NADH + 4-Amino-butanoic acid + H+( EC:1.2.1.19 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003206 Sarcosine + O2 + H2O => Glycine + Formaldehyde + H2O2( EC:1.5.3.1 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002730 Aldehyde + NADP+ + H2O = Carboxylate + NADPH + H+( EC:1.2.1.5 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002727 Alkane + Reduced flavoprotein + O2 = ROH + Oxidized flavoprotein + H2O( EC:1.14.14.1 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003843 6-Lactoyl-5,6,7,8-tetrahydropterin + NADP+ = 6-Pyruvoyltetrahydropterin + NADPH + H+( EC:1.1.1.153 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002762 Pyruvic acid + Enzyme N6-(lipoyl)lysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2( EC:1.2.4.1 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002792 NADP+ + (S)-Malic acid = NADPH + Pyruvic acid + CO2 + H+( EC:1.1.1.40 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002976 NADP+ + GDP-L-fucose = NADPH + GDP-4-dehydro-6-deoxy-D-mannose + H+( EC:1.1.1.271 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002723 Secondary alcohol + NADP+ = Ketone + NADPH + H+( EC:1.1.1.184 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002724 Alditol + NADP+ = Aldose + NADPH + H+( EC:1.1.1.21 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002726 procollagen L-proline + 2-Oxo-glutaric acid + O2 = procollagen trans-4-hydroxy-L-proline + Succinic acid + CO2( EC:1.14.11.2 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002733 D-amino acid + H2O + O2 = 2-oxo acid + NH3 + H2O2( EC:1.4.3.3 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002734 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002735 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.21 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002736 protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+( EC:1.8.1.4 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002763 2-Oxo-glutaric acid + Enzyme N6-(lipoyl)lysine = [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO2( EC:1.2.4.2 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002770 NAD+ + D-Sorbitol = NADH + D-Fructose + H+( EC:1.1.1.14 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002773 NADPH + Leukotriene B4 + O2 + H+ => NADP+ + 20-OH-Leukotriene B4 + H2O( EC:1.14.13.30 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002774 NAD+ + (R)-Lactic acid = NADH + Pyruvic acid + H+( EC:1.1.1.28 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002778 NADP+ + 10-Formyl-tetrahydro-folic acid + H2O => NADPH + Tetrahydrofolate + CO2 + H+( EC:1.5.1.6 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002812 Pyridoxine + O2 => Pyridoxal + H2O2( EC:1.4.3.5 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002832 Coproporphyrinogen III + O2 => Protoporphyrinogen IX + 2 CO2 + 2 H2O( EC:1.3.3.3 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002837 NADP+ + Cholesterol = NADPH + 7-Dehydro-cholesterol + H+( EC:1.3.1.21 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002852 NADP+ + 5,6-Dihydro-thymine = NADPH + Thymine + H+( EC:1.3.1.2 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002871 NADPH + Folic acid + H+ => NADP+ + 7,8-Dihydro-folic acid( EC:1.5.1.3 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002874 NAD+ + (S)-Lactic acid = NADH + Pyruvic acid + H+( EC:1.1.1.27 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002903 Lipoylprotein + Glycine => S-Aminomethyl-dihydro-lipoylprotein + CO2( EC:1.4.4.2 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002911 NAD+ + (S)-Malic acid = NADH + Pyruvic acid + CO2 + H+( EC:1.1.1.38 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002926 Arachidonic acid + O2 => 15(S)-HPETE( EC:1.13.11.33 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002928 NAD+ + (S)-Malic acid = NADH + Oxaloacetic acid + H+( EC:1.1.1.37 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002933 (S)-2-Methylbutanoyl-CoA + Acceptor = 2-Methylbut-2-enoyl-CoA + Reduced acceptor( EC:1.3.99.2 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002934 NAD+ + L-Saccharopine + H2O = NADH + L-2-Amino-adipate 6-semialdehyde + L-Glutamic acid + H+( EC:1.5.1.9 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002935 Squalene + O2 + NADPH + H+ => (S)-2,3-Epoxy-squalene + H2O + NADP+( EC:1.14.99.7 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002968 Arachidonic acid + O2 => 5(S)-HPETE( EC:1.13.11.34 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002977 NADPH + L-Lysine + 2-Oxo-glutaric acid + H+ => NADP+ + L-Saccharopine + H2O( EC:1.5.1.8 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002982 Pyridoxamine + O2 + H2O => Pyridoxal + H2O2 + NH3( EC:1.4.3.5 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002985 NAD+ + D-Glycerate 3-phosphate = NADH + 3-Phospho-hydroxy-pyruvic acid + H+( EC:1.1.1.95 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003001 NAD+ + L-4-Hydroxy-glutamate semialdehyde + H2O => NADH + L-erythro-4-Hydroxy-glutamic acid + H+( EC:1.5.1.12 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003009 NADPH + Prostaglandin D2 + H+ => NADP+ + 11-epi-Prostaglandin F2alpha( EC:1.1.1.188 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003021 NAD+ + CoA + (S)-Methyl-malonate semialdehyde => NADH + Propanoyl-CoA + CO2 + H+( EC:1.2.1.27 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003022 NADH + L-1-Pyrroline-3-hydroxy-5-carboxylic acid + H+ = NAD+ + trans-4-Hydroxy-L-proline( EC:1.5.1.2 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003056 NAD+ + 5,10-Methylene-tetrahydro-folic acid = NADH + 5,10-Methenyl-tetrahydro-folic acid( EC:1.5.1.15 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003064 Tyramine + O2 + NADH + H+ => Dopamine + NAD+ + H2O( EC:1.14.18.1 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003066 NADP+ + 6-Phospho-D-gluconic acid => NADPH + D-Ribulose 5-phosphate + CO2 + H+( EC:1.1.1.44 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003067 Succinic acid + Ubiquinone = Fumaric acid + Ubiquinol( EC:1.3.5.1 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003069 Arachidonic acid + O2 => 12(S)-HPETE( EC:1.13.11.31 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003091 Prostaglandin G2 + Reduced acceptor => Prostaglandin H2 + H2O + Acceptor( EC:1.14.99.1 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003094 L-Cysteine + O2 => L-Cysteine-sulfinic acid( EC:1.13.11.20 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003107 NADP+ + Hydroxy-acetone = NADPH + Methyl-glyoxal + H+( EC:1.1.1.- ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003140 4-Trimethyl-ammonio-butanoic acid + 2-Oxo-glutaric acid + O2 => Carnitine + Succinic acid + CO2( EC:1.14.11.1 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003145 Butanoyl-CoA + NAD+ = Crotonoyl-CoA + NADH + H+( EC:1.3.99.2 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003149 NADPH + 5alpha-Cholest-7-en-3beta-ol + O2 + H+ => NADP+ + 7-Dehydro-cholesterol + 2 H2O( EC:1.14.21.6 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003166 NAD+ + L-2-Amino-adipate 6-semialdehyde + H2O = NADH + L-2-Amino-adipic acid + H+( EC:1.2.1.31 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003170 NAD+ + 3-Mercapto-lactic acid = NADH + 3-Mercapto-pyruvic acid + H+( EC:1.1.1.27 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003184 5-Hydroxy-L-Tryptophan + O2 => 5-Hydroxy-N-formyl-kynurenine( EC:1.13.11.52 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003190 N6,N6,N6-Trimethyl-L-lysine + 2-Oxo-glutaric acid + O2 => 3-Hydroxy-N6,N6,N6-trimethyl-L-lysine + Succinic acid + CO2( EC:1.14.11.8 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003195 Pyridoxine 5'-phosphate + O2 => Pyridoxal 5'-phosphate + H2O2( EC:1.4.3.5 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003196 NADPH + L-Kynurenine + O2 + H+ => NADP+ + 3-Hydroxy-L-kynurenine + H2O( EC:1.14.13.9 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003208 NADP+ + 5-Methyl-tetrahydro-folic acid => NADPH + 5,10-Methylene-tetrahydro-folic acid + H+( EC:1.5.1.20 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003212 NAD+ + IMP + H2O => NADH + XMP + H+( EC:1.1.1.205 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003215 3-Methyl-butanoyl-CoA + FAD => 3-Methylbut-2-enoyl-CoA + FADH2( EC:1.3.99.10 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003223 N,N-Dimethyl-glycine + H2O + Acceptor => Sarcosine + Formaldehyde + Reduced acceptor( EC:1.5.99.2 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003228 Arachidonic acid + 2 O2 => Prostaglandin G2( EC:1.14.99.1 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003236 L-Tryptophan + O2 => N-Formyl-L-kynurenine( EC:1.13.11.11 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003248 NADP+ + beta-D-Glucose 6-phosphate => NADPH + D-Glucono-1,5-lactone 6-phosphate + H+( EC:1.1.1.49 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003260 Pyridoxamine 5'-phosphate + O2 + H2O => Pyridoxal 5'-phosphate + H2O2 + NH3( EC:1.4.3.5 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003262 Dopamine + L-Ascorbic acid + O2 => L-Noradrenaline + L-Dehydro-ascorbic acid + H2O( EC:1.14.17.1 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003268 Xanthine + H2O + O2 => Uric acid + H2O2( EC:1.17.3.2 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003278 NADH + (S)-Methyl-malonate semialdehyde + H+ => NAD+ + (S)-3-Hydroxyisobutyrate( EC:1.1.1.31 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003288 NAD+ + L-Glutamate 5-semialdehyde + H2O => NADH + L-Glutamic acid + H+( EC:1.5.1.12 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003305 D-Aspartic acid + H2O + O2 => Oxaloacetic acid + NH3 + H2O2( EC:1.4.3.1 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003312 NADP+ + 5,10-Methylene-tetrahydro-folic acid = NADPH + 5,10-Methenyl-tetrahydro-folic acid( EC:1.5.1.5 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003322 2-Methyl-propanoyl-CoA + Acceptor = 2-Methylprop-2-enoyl-CoA + Reduced acceptor( EC:1.3.99.2 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003851 Arachidonic acid + O2 = Leukotriene A4 + H2O( EC:1.13.11.34 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003852 Arachidonic acid + Reduced acceptor + 2 O2 = Prostaglandin H2 + Acceptor + H2O( EC:1.14.99.1 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003856 NADPH + 2 N-(omega)-Hydroxyarginine + 2 O2 + H+ = NADP+ + 2 Nitric oxide + 2 L-Citrulline + 2 H2O( EC:1.14.13.39 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0000916 Reduction http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002731 Aldehyde + H2O + O2 = Carboxylate + H2O2( EC:1.2.3.1 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003842 Tetrahydrobiopterin + NADP+ = 6-Lactoyl-5,6,7,8-tetrahydropterin + NADPH + H+( EC:1.1.1.153 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002938 myo-Inositol + O2 => D-Glucuronic acid + H2O( EC:1.13.99.1 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0001058 Oxidation/Reduction in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0001059 Oxidation/Reduction in cytosol http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002728 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin( EC:1.17.4.1 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003125 NAD+ + 2-Hydroxy-butanoic acid = NADH + 2-Oxo-butanoic acid + H+( EC:1.1.1.27 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002844 Glutaryl-CoA + Acceptor => Crotonoyl-CoA + CO2 + Reduced acceptor( EC:1.3.99.7 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002729 Aldehyde + NAD+ + H2O = Carboxylate + NADH + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003214 3 NADPH + 2 L-Arginine + 4 O2 + 3 H+ = 3 NADP+ + 2 L-Citrulline + 2 Nitric oxide + 4 H2O( EC:1.14.13.39 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002722 Alcohol + NAD+ = Aldehyde + NADH + H+( EC:1.1.1.1 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0000382 Oxidation http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003176 NADPH + GMP + H+ => NADP+ + IMP + NH3( EC:1.7.1.7 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003271 4-Hydroxy-phenyl-pyruvic acid + O2 => CO2 + 2,5-Dihydroxy-phenyl-acetic acid( EC:1.13.11.27 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003146 NAD+ + Isocitric acid = NADH + 2-Oxo-glutaric acid + CO2 + H+( EC:1.1.1.41 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002870 2,5-Dihydroxy-phenyl-acetic acid + O2 => 4-Maleyl-acetoacetic acid( EC:1.13.11.5 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003095 3-Hydroxy-anthranilic acid + O2 => 2-Amino-3-carboxy-muconate semialdehyde( EC:1.13.11.6 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002866 NADPH + 6,7-Dihydro-biopterin + H+ => NADP+ + Tetrahydrobiopterin( EC:1.5.1.34 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003032 2 NADPH + (S)-3-Hydroxy-3-methyl-glutaryl-CoA + 2 H+ => 2 NADP+ + CoA + (R)-Mevalonic acid( EC:1.1.1.34 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002732 Acyl-CoA + Acceptor = 2,3-dehydroacyl-CoA + Reduced acceptor( EC:1.3.99.3 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002946 NAD+ + L-Glutamic acid + H2O = NADH + 2-Oxo-glutaric acid + NH3 + H+( EC:1.4.1.3 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002918 5(S)-HPETE => Leukotriene A4 + H2O( EC:1.13.11.34 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003098 NADPH + Prostaglandin E2 + H+ => NADP+ + Prostaglandin F2alpha( EC:1.1.1.189 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003267 2 NADPH + Folic acid + 2 H+ => 2 NADP+ + Tetrahydrofolate( EC:1.5.1.3 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003063 NADP+ + 2 Glutathione = NADPH + Glutathione disulfide + H+( EC:1.8.1.7 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003855 L-Arginine + O2 + NADPH + H+ = N-(omega)-Hydroxyarginine + NADP+ + H2O( EC:1.14.13.39 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002818 NAD+ + Succinate semialdehyde + H2O = NADH + Succinic acid + H+( EC:1.2.1.24 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003258 NADPH + 7,8-Dihydro-folic acid + H+ => NADP+ + Tetrahydrofolate( EC:1.5.1.3 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003264 NAD+ + L-1-Pyrroline-3-hydroxy-5-carboxylic acid + 2 H2O => NADH + L-erythro-4-Hydroxy-glutamic acid + H+( EC:1.5.1.12 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003158 NADH + (S)-1-Pyrroline-5-carboxylic acid + H+ = NAD+ + L-Proline( EC:1.5.1.2 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003051 NAD+ + 4-Trimethyl-ammonio-butanal + H2O = NADH + 4-Trimethyl-ammonio-butanoic acid + H+( EC:1.2.1.47 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002809 NADP+ + 5,6-Dihydro-uracil = NADPH + Uracil + H+( EC:1.3.1.2 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003172 NADPH + Cholesterol + O2 + H+ = NADP+ + 7alpha-Hydroxycholesterol + H2O( EC:1.14.13.17 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003199 NAD+ + (S)-1-Pyrroline-5-carboxylic acid + 2 H2O => NADH + L-Glutamic acid + H+( EC:1.5.1.12 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003074 NADH + 1,3-Bisphospho-D-glyceric acid + H+ = NAD+ + D-Glyceraldehyde 3-phosphate + Orthophosphate( EC:1.2.1.12 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002821 NAD+ + (R)-3-Hydroxy-butanoic acid = NADH + Acetoacetic acid + H+( EC:1.1.1.30 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003204 NAD+ + N-Succinyl-L-glutamate 5-semialdehyde + H2O => NADH + N-Succinyl-L-glutamic acid + H+( EC:1.2.1.71 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003111 2 Protoporphyrinogen IX + 3 O2 => 2 Protoporphyrin IX + 6 H2O( EC:1.3.3.4 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003197 L-Tyrosine + Tetrahydrobiopterin + O2 => L-Dopa + 6,7-Dihydro-biopterin + H2O( EC:1.14.16.2 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0003280 NADH + L-Lysine + 2-Oxo-glutaric acid + H+ => NAD+ + L-Saccharopine + H2O( EC:1.5.1.7 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002902 2 3-Hydroxy-anthranilic acid + 4 O2 = Cinnavalininate + 2 O2.- + 2 H2O2 + 2 H+( EC:1.11.1.6 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002882 (S)-Dihydro-orotic acid + O2 = Orotic acid + H2O2( EC:1.3.3.1 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0002900 2 NADPH + 6-Pyruvoyltetrahydropterin + 2 H+ => 2 NADP+ + Tetrahydrobiopterin( EC:1.1.1.153 ) http://purl.obolibrary.org/obo/IEV_0000914 Oxidation/Reduction http://purl.obolibrary.org/obo/IEV_0001008 Caspase8 activation signaling http://purl.obolibrary.org/obo/IEV_0000929 Caspase8/10 activation signaling http://purl.obolibrary.org/obo/IEV_0001004 Caspase10 activation signaling http://purl.obolibrary.org/obo/IEV_0000929 Caspase8/10 activation signaling http://purl.obolibrary.org/obo/IEV_0000944 Myristoylation of Bid by NMT1 in cytosol http://purl.obolibrary.org/obo/IEV_0000945 Myristoylation in cytosol http://purl.obolibrary.org/obo/IEV_0000968 Inactivation of Bcl-2 by Bad in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000977 Inactivation of Bcl-2 family by pro-apoptotic factor in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000969 Inactivation of Bcl-xL by Bad in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000977 Inactivation of Bcl-2 family by pro-apoptotic factor in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000973 Inactivation of Bcl-xL by Bim in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000977 Inactivation of Bcl-2 family by pro-apoptotic factor in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000976 Inactivation of Bcl-xL by PUMA in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000977 Inactivation of Bcl-2 family by pro-apoptotic factor in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000972 Inactivation of Bcl-xL by Bid in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000977 Inactivation of Bcl-2 family by pro-apoptotic factor in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000974 Inactivation of Bcl-2 by NOXA in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000977 Inactivation of Bcl-2 family by pro-apoptotic factor in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000971 Inactivation of Bcl-2 by Bim in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000977 Inactivation of Bcl-2 family by pro-apoptotic factor in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000975 Inactivation of Bcl-2 by PUMA in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000977 Inactivation of Bcl-2 family by pro-apoptotic factor in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000176 Permeabilization of mitochondria and Translocation of Cyt c from mitochondria to cytosol http://purl.obolibrary.org/obo/IEV_0000984 Permeabilization of mitochondria and Translocation of cytochrome c/SMAC from mitochondria to cytosol http://purl.obolibrary.org/obo/IEV_0000986 Permeabilization of mitochondria and Translocation of SMAC from mitochondria to cytosol http://purl.obolibrary.org/obo/IEV_0000984 Permeabilization of mitochondria and Translocation of cytochrome c/SMAC from mitochondria to cytosol http://purl.obolibrary.org/obo/IEV_0000304 DMEM (medium) http://purl.obolibrary.org/obo/IEV_0000311 ES cell medium http://purl.obolibrary.org/obo/IEV_0000295 KBM (medium) http://purl.obolibrary.org/obo/IEV_0000316 Epidermal keratinocyto medium http://purl.obolibrary.org/obo/IEV_0000307 KGM-2 (medium) http://purl.obolibrary.org/obo/IEV_0000316 Epidermal keratinocyto medium http://purl.obolibrary.org/obo/IEV_0000357 KGM (medium) http://purl.obolibrary.org/obo/IEV_0000316 Epidermal keratinocyto medium http://purl.obolibrary.org/obo/IEV_0000296 KBM-2 (medium) http://purl.obolibrary.org/obo/IEV_0000316 Epidermal keratinocyto medium http://purl.obolibrary.org/obo/IEV_0000337 Ham's F-10 medium http://purl.obolibrary.org/obo/IEV_0000333 Hybridoma cell medium http://purl.obolibrary.org/obo/IEV_0000339 Ham's F-12 medium http://purl.obolibrary.org/obo/IEV_0000333 Hybridoma cell medium http://purl.obolibrary.org/obo/IEV_0000535 Fyn activation signaling (through autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001606 Src family activation signaling (through autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001781 Negative regulation of Androgen receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001777 Negative regulation of Steroid receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001782 Positive regulation of Androgen receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001778 Positive regulation of Steroid receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001829 SUMOylation in nucleus http://purl.obolibrary.org/obo/IEV_0001828 SUMOylation in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0001055 SUMOylation in cytosol http://purl.obolibrary.org/obo/IEV_0001828 SUMOylation in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0001860 Negative regulation of (negative regulation of AKT(PKB) activation signaling) http://purl.obolibrary.org/obo/IEV_0001859 Regulation of (negative regulation of AKT(PKB) activation signaling) http://purl.obolibrary.org/obo/IEV_0000869 Ubiquitination of p53 by Mdm2 in nucleus http://purl.obolibrary.org/obo/IEV_0001932 Ubiquitination of p53 by ubiquitin ligase in nucleus http://purl.obolibrary.org/obo/IEV_0003433 Phosphorylation of STAT1 by JAK2_p in cytosol http://purl.obolibrary.org/obo/IEV_0000446 Phosphorylation of STAT by JAK_p in cytosol http://purl.obolibrary.org/obo/IEV_0002127 Phosphorylation of STAT2 by JAK1_p and TYK2_p in cytosol http://purl.obolibrary.org/obo/IEV_0000446 Phosphorylation of STAT by JAK_p in cytosol http://purl.obolibrary.org/obo/IEV_0002128 Phosphorylation of STAT1 by JAK1_p and TYK2_p in cytosol http://purl.obolibrary.org/obo/IEV_0000446 Phosphorylation of STAT by JAK_p in cytosol http://purl.obolibrary.org/obo/IEV_0002129 Phosphorylation of STAT3 by JAK1_p and TYK2_p in cytosol http://purl.obolibrary.org/obo/IEV_0000446 Phosphorylation of STAT by JAK_p in cytosol http://purl.obolibrary.org/obo/IEV_0002130 Phosphorylation of STAT3 by JAK1_p and JAK2_p in cytosol http://purl.obolibrary.org/obo/IEV_0000446 Phosphorylation of STAT by JAK_p in cytosol http://purl.obolibrary.org/obo/IEV_0002131 Phosphorylation of STAT5 by JAK1_p and JAK3_p in cytosol http://purl.obolibrary.org/obo/IEV_0000446 Phosphorylation of STAT by JAK_p in cytosol http://purl.obolibrary.org/obo/IEV_0002132 Phosphorylation of STAT4 by JAK2_p and TYK2_p in cytosol http://purl.obolibrary.org/obo/IEV_0000446 Phosphorylation of STAT by JAK_p in cytosol http://purl.obolibrary.org/obo/IEV_0002271 Phosphorylation of STAT1 by JAK1_p and JAK2_p in cytosol http://purl.obolibrary.org/obo/IEV_0000446 Phosphorylation of STAT by JAK_p in cytosol http://purl.obolibrary.org/obo/IEV_0002296 Phosphorylation of STAT6 by JAK1_p and JAK3_p in cytosol http://purl.obolibrary.org/obo/IEV_0000446 Phosphorylation of STAT by JAK_p in cytosol http://purl.obolibrary.org/obo/IEV_0002322 Phosphorylation of STAT5 by JAK2_p in cytosol http://purl.obolibrary.org/obo/IEV_0000446 Phosphorylation of STAT by JAK_p in cytosol http://purl.obolibrary.org/obo/IEV_0002659 Phosphorylation of STAT3 by JAK2_p in cytosol http://purl.obolibrary.org/obo/IEV_0000446 Phosphorylation of STAT by JAK_p in cytosol http://purl.obolibrary.org/obo/IEV_0003608 Phosphorylation of STAT6 by JAK1_p and TYK2_p in cytosol http://purl.obolibrary.org/obo/IEV_0000446 Phosphorylation of STAT by JAK_p in cytosol http://purl.obolibrary.org/obo/IEV_0003600 Phosphorylation of STAT3 by JAK2_p and TYK2_p in cytosol http://purl.obolibrary.org/obo/IEV_0000446 Phosphorylation of STAT by JAK_p in cytosol http://purl.obolibrary.org/obo/IEV_0001213 Binding of Estrogen receptor and NCOR1 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001212 Binding of Estrogen receptor and corepressor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001214 Binding of Estrogen receptor and NCOR2 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001212 Binding of Estrogen receptor and corepressor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003376 Autophosphorylation of JAK1 and TYK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000052 Autophosphorylation of Jak in cytosol http://purl.obolibrary.org/obo/IEV_0002158 Autophosphorylation of TYK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000052 Autophosphorylation of Jak in cytosol http://purl.obolibrary.org/obo/IEV_0002160 Autophosphorylation of JAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000052 Autophosphorylation of Jak in cytosol http://purl.obolibrary.org/obo/IEV_0002161 Autophosphorylation of JAK3 in cytosol http://purl.obolibrary.org/obo/IEV_0000052 Autophosphorylation of Jak in cytosol http://purl.obolibrary.org/obo/IEV_0003375 Autophosphorylation of JAK1 and JAK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000052 Autophosphorylation of Jak in cytosol http://purl.obolibrary.org/obo/IEV_0003378 Autophosphorylation of JAK1 and JAK3 in cytosol http://purl.obolibrary.org/obo/IEV_0000052 Autophosphorylation of Jak in cytosol http://purl.obolibrary.org/obo/IEV_0003377 Autophosphorylation of JAK2 and TYK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000052 Autophosphorylation of Jak in cytosol http://purl.obolibrary.org/obo/IEV_0002004 Negative regulation of (G alpha s GDP-GTP exchange signaling) http://purl.obolibrary.org/obo/IEV_0002006 Negative regulation of heterotrimeric GPCR signaling pathway (through G alpha s, cholera toxin, adenylate cyclase and cAMP) http://purl.obolibrary.org/obo/IEV_0002002 Negative regulation of (Binding of G alpha s-GTP and adenylate cyclase) http://purl.obolibrary.org/obo/IEV_0002006 Negative regulation of heterotrimeric GPCR signaling pathway (through G alpha s, cholera toxin, adenylate cyclase and cAMP) http://purl.obolibrary.org/obo/IEV_0002085 Negative regulation of (GDP-GTP exchange of Rap1 by Epac1) http://purl.obolibrary.org/obo/IEV_0000693 Negative regulation of heterotrimeric GPCR signaling pathway (through G alpha s) http://purl.obolibrary.org/obo/IEV_0003821 Binding of PDGF receptor_p and PLC gamma1 in cytosol http://purl.obolibrary.org/obo/IEV_0000283 Binding of RTK and PLC gamma in cytosol http://purl.obolibrary.org/obo/IEV_0002476 Binding of TRK_p and PLC gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000283 Binding of RTK and PLC gamma in cytosol http://purl.obolibrary.org/obo/IEV_0002483 Binding of KDR_p and PLC gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000283 Binding of RTK and PLC gamma in cytosol http://purl.obolibrary.org/obo/IEV_0002489 Binding of FGFR_p and PLC gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000283 Binding of RTK and PLC gamma in cytosol http://purl.obolibrary.org/obo/IEV_0003335 Phosphorylation of ETS1/2 by ERK1/2_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003869 Phosphorylation of ets domain transcription factor by ERK_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003834 Phosphorylation of Sap-1 by ERK1/2_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003869 Phosphorylation of ets domain transcription factor by ERK_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003707 Phosphorylation of Tel-1 by ERK1/2_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003869 Phosphorylation of ets domain transcription factor by ERK_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000711 ADP ribosylation in plasma membrane http://purl.obolibrary.org/obo/IEV_0000709 ADP ribosylation http://purl.obolibrary.org/obo/IEV_0000710 ADP ribosylation in cytosol http://purl.obolibrary.org/obo/IEV_0000709 ADP ribosylation http://purl.obolibrary.org/obo/IEV_0000862 Positive regulation of RTK signaling pathway (through Grb2, Sos, Ras, RalGDS, Ral and PLD) http://purl.obolibrary.org/obo/IEV_0000836 Positive regulation of RTK signaling pathway http://purl.obolibrary.org/obo/IEV_0000861 Negative regulation of RTK signaling pathway (through Grb2, Sos, Ras, RalGDS, Ral and PLD) http://purl.obolibrary.org/obo/IEV_0000835 Negative regulation of RTK signaling pathway http://purl.obolibrary.org/obo/IEV_0000541 Positive regulation of Caspase cascade (through mitochondria) http://purl.obolibrary.org/obo/IEV_0001018 Regulation of Caspase cascade (through mitochondria) http://purl.obolibrary.org/obo/IEV_0001023 Positive regulation of Caspase cascade (not through mitochondria) http://purl.obolibrary.org/obo/IEV_0001021 Regulation of Caspase cascade (not through mitochondria) http://purl.obolibrary.org/obo/IEV_0000706 Binding of Ras-GTP and GAP in cytosol http://purl.obolibrary.org/obo/IEV_0000679 Binding of small GTPase-GTP and GAP in cytosol http://purl.obolibrary.org/obo/IEV_0000417 Translocation of Coniferyl alcohol to cell wall http://purl.obolibrary.org/obo/IEV_0000429 Translocation from cytosol to cell wall http://purl.obolibrary.org/obo/IEV_0000418 Translocation of 4-Coumaryl alcohol to cell wall http://purl.obolibrary.org/obo/IEV_0000429 Translocation from cytosol to cell wall http://purl.obolibrary.org/obo/IEV_0000428 Translocation of sinapyl alcohol to cell wall http://purl.obolibrary.org/obo/IEV_0000429 Translocation from cytosol to cell wall http://purl.obolibrary.org/obo/IEV_0003731 Binding of EGFR and Kek in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane http://purl.obolibrary.org/obo/IEV_0000846 Dimerization of RTK in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane http://purl.obolibrary.org/obo/IEV_0000045 Binding of cytokine and cytokine receptors and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane http://purl.obolibrary.org/obo/IEV_0000258 Complex formation of TCR-CD3 in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane http://purl.obolibrary.org/obo/IEV_0000581 Complex formation of integrin complex and caveolin in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane http://purl.obolibrary.org/obo/IEV_0000924 Trimerization of Fas in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane http://purl.obolibrary.org/obo/IEV_0001271 Complex formation of BCR in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane http://purl.obolibrary.org/obo/IEV_0001897 Binding of phosphatidylserine and PKC and active conformational change of PKC in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane http://purl.obolibrary.org/obo/IEV_0002497 Binding of BMP2:BMP receptor I and BMP receptor II in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane http://purl.obolibrary.org/obo/IEV_0002527 Binding of integrin alpha and caveolin-1 in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane http://purl.obolibrary.org/obo/IEV_0002528 Binding of caveolin-1 and Fyn in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane http://purl.obolibrary.org/obo/IEV_0002590 Binding of Ptc and Smo in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane http://purl.obolibrary.org/obo/IEV_0003529 Dimerization of Toll by Spaetzle in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane http://purl.obolibrary.org/obo/IEV_0000803 Trimerization of TNFR2 in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane http://purl.obolibrary.org/obo/IEV_0000936 Trimerization of DR4/5 in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane http://purl.obolibrary.org/obo/IEV_0000253 Trimerization of TNFR1 in plasma membrane http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane http://purl.obolibrary.org/obo/IEV_0001311 Nuclear import of calcineurin http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0000034 Nuclear import of beta catenin http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0000158 Nuclear import of R-Smad:Smad4 http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0000761 Nuclear import of Notch (NIC) from the cytosol http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0001079 Nuclear import of Cdk2_p:cyclin E http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0001605 Nuclear import of EndoG http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0001705 Nuclear import of HDAC5/7 http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0001775 Nuclear import of Androgen receptor:Hsp90 http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0001935 Nuclear import of Mdm4 http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0002205 Nuclear transport of AP-1 http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0002603 Nuclear import of Ci/Gli http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0002604 Nuclear import of Ci/GliR http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0003528 Nuclear import of Dorsal:DIF http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0003538 Nuclear import of Dorsal http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0003539 Nuclear import of TRAF2:Ref2P:aPKC http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0001072 Nuclear import of Cdk4/6_p:cyclin D http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0003521 Nuclear import of DIF http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0003471 Nuclear import of Relish http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0001016 Nuclear import of CAD http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0001205 Nuclear import of Estrogen http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0001012 Nuclear import of AIF http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0001171 Nuclear import of Notch (NIC) from the plasma membrane http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0003652 Nuclear import of AKT http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0001771 Nuclear import of Androgen http://purl.obolibrary.org/obo/IEV_0000018 Nuclear import http://purl.obolibrary.org/obo/IEV_0001702 Nuclear export of 14-3-3:HDAC5/7:Crm1 http://purl.obolibrary.org/obo/IEV_0000019 Nuclear export http://purl.obolibrary.org/obo/IEV_0001976 Nuclear export of TCF http://purl.obolibrary.org/obo/IEV_0000019 Nuclear export http://purl.obolibrary.org/obo/IEV_0003590 Nuclear export of R-Smad http://purl.obolibrary.org/obo/IEV_0000019 Nuclear export http://purl.obolibrary.org/obo/IEV_0003675 Nuclear export of FOXO http://purl.obolibrary.org/obo/IEV_0000019 Nuclear export http://purl.obolibrary.org/obo/IEV_0003730 Nuclear export of Tel-1:Crm1 http://purl.obolibrary.org/obo/IEV_0000019 Nuclear export http://purl.obolibrary.org/obo/IEV_0000147 Dephosphorylation of cytokine receptor by PTP in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000146 Dephosphorylation of Jak by PTP in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000149 Dephosphorylation of STAT dimer by PTP in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000413 Dephosphorylation of Bad_p by calcineurin in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000502 Dephosphorylation of Insulin receptor by PTP in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000526 Dephosphorylation of ZAP-70_p by SHIP-1 in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000613 Dephosphorylation of FAK by PTEN in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000801 Dephosphorylation of PPAR by phosphatase in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001608 Dephosphorylation of Src family_p by PTP and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001611 Dephosphorylation of Src family_p by PTP in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001701 Dephosphorylation of HDAC5/7 by protein phosphatase in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001955 Dephosphorylation of beta-catenin by PP2A in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002424 Dephosphorylation of NMDA glutamate receptor by PP1 in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002425 Dephosphorylation of L-type Ca2+ channel_p by PP1 in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002429 Dephosphorylation of DARPP-32_p by PP2A in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003630 Dephosphorylation of Raf by PP2A in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003802 Dephosphorylation of FGFR by CLR-1 in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003832 Dephosphorylation of PDGF receptor by SHP-2 in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001309 Dephosphorylation of NF-AT by calcineurin in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003455 Endoderm induction Wnt signaling pathway http://purl.obolibrary.org/obo/IEV_0000027 Wnt signaling pathway http://purl.obolibrary.org/obo/IEV_0000174 Binding outside the mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000170 Binding of Bad and Bcl-2/Bcl-xL in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000033 Binding in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0002587 Activation of Smo http://purl.obolibrary.org/obo/IEV_0000038 Activation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0001573 Hydrogen peroxide treatment http://purl.obolibrary.org/obo/IEV_0000043 Inorganic chemical treatment http://purl.obolibrary.org/obo/IEV_0002154 Binding of IL-6 and IL-6 receptor and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0000045 Binding of cytokine and cytokine receptors and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0002152 Binding of IFN alpha and IFN alpha receptor and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0000045 Binding of cytokine and cytokine receptors and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0002153 Binding of IFN gamma and IFN gamma receptor and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0000045 Binding of cytokine and cytokine receptors and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0002171 Binding of LIF and LIF receptor and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0000045 Binding of cytokine and cytokine receptors and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0002324 Binding of GH and GH receptor and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0000045 Binding of cytokine and cytokine receptors and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0003610 Binding of IL-13 and IL-13 receptor and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0000045 Binding of cytokine and cytokine receptors and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0003621 Binding of IL5 and IL5 receptor and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0000045 Binding of cytokine and cytokine receptors and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0002656 Binding of TPO and TPO receptor and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0000045 Binding of cytokine and cytokine receptors and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0003434 Binding of EPO and EPO receptor complex and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0000045 Binding of cytokine and cytokine receptors and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0003596 Binding of IL-23 and IL-23 receptor and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0000045 Binding of cytokine and cytokine receptors and conformational change of receptors in plasma membrane http://purl.obolibrary.org/obo/IEV_0002136 Binding of STAT1:STAT3 heterodimer and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000049 Binding of STAT dimer and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002100 Binding of STAT dimer and GAS in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000049 Binding of STAT dimer and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002138 Binding of ISGF3 and ISRE in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000049 Binding of STAT dimer and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002300 Binding of STAT6 homodimer and promoter in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000049 Binding of STAT dimer and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003605 Binding of STAT3:STAT4 heterodimer and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000049 Binding of STAT dimer and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002135 Binding of STAT3 homodimer and SIE element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000049 Binding of STAT dimer and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002146 Binding of IFN alpha receptor and JAK1 and TYK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000051 Binding of cytokine receptor and JAK in cytosol http://purl.obolibrary.org/obo/IEV_0002147 Binding of IFN gamma receptor and JAK1 and JAK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000051 Binding of cytokine receptor and JAK in cytosol http://purl.obolibrary.org/obo/IEV_0002148 Binding of IL-6 receptor and JAK1 and JAK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000051 Binding of cytokine receptor and JAK in cytosol http://purl.obolibrary.org/obo/IEV_0002149 Binding of IL-10 receptor and JAK1 and TYK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000051 Binding of cytokine receptor and JAK in cytosol http://purl.obolibrary.org/obo/IEV_0002150 Binding of IL-2 receptor and JAK1 and JAK3 in cytosol http://purl.obolibrary.org/obo/IEV_0000051 Binding of cytokine receptor and JAK in cytosol http://purl.obolibrary.org/obo/IEV_0002151 Binding of IL-12 receptor and JAK2 and TYK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000051 Binding of cytokine receptor and JAK in cytosol http://purl.obolibrary.org/obo/IEV_0002157 Binding of LIF receptor and JAK1 and JAK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000051 Binding of cytokine receptor and JAK in cytosol http://purl.obolibrary.org/obo/IEV_0002293 Binding of IL-4 receptor and JAK1 and JAK3 in cytosol http://purl.obolibrary.org/obo/IEV_0000051 Binding of cytokine receptor and JAK in cytosol http://purl.obolibrary.org/obo/IEV_0002319 Binding of GH receptor and JAK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000051 Binding of cytokine receptor and JAK in cytosol http://purl.obolibrary.org/obo/IEV_0002326 Binding of IL3 receptor and JAK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000051 Binding of cytokine receptor and JAK in cytosol http://purl.obolibrary.org/obo/IEV_0002330 Binding of IL-7 receptor and JAK1 and JAK3 in cytosol http://purl.obolibrary.org/obo/IEV_0000051 Binding of cytokine receptor and JAK in cytosol http://purl.obolibrary.org/obo/IEV_0002655 Binding of TPO receptor and JAK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000051 Binding of cytokine receptor and JAK in cytosol http://purl.obolibrary.org/obo/IEV_0000166 AKT(PKB)-Bad signaling http://purl.obolibrary.org/obo/IEV_0001699 AKT signaling http://purl.obolibrary.org/obo/IEV_0000055 PKA-Bad signaling http://purl.obolibrary.org/obo/IEV_0000054 Bad inactivation signaling http://purl.obolibrary.org/obo/IEV_0000056 RSK-Bad signaling http://purl.obolibrary.org/obo/IEV_0000054 Bad inactivation signaling http://purl.obolibrary.org/obo/IEV_0001581 Carbohydrate treatment http://purl.obolibrary.org/obo/IEV_0000064 Organic chemical treatment http://purl.obolibrary.org/obo/IEV_0000059 TGF beta super family signaling pathway (through p38 cascade) http://purl.obolibrary.org/obo/IEV_0000090 TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0002266 TGF beta super family signaling pathway (through JNK cascade) http://purl.obolibrary.org/obo/IEV_0000090 TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0001139 TGF beta super family signaling (through p15) http://purl.obolibrary.org/obo/IEV_0000391 Negative regulation of G1-S-phase transition http://purl.obolibrary.org/obo/IEV_0001149 TGF beta super family signaling (through p16) http://purl.obolibrary.org/obo/IEV_0000090 TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0001150 TGF beta super family signaling (through p27) http://purl.obolibrary.org/obo/IEV_0000090 TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0001140 TGF beta super family signaling (through p21) http://purl.obolibrary.org/obo/IEV_0000090 TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0000063 IL1 signaling (through IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0000110 IL1 signaling pathway http://purl.obolibrary.org/obo/IEV_0000224 IL-1 signaling (through JNK cascade) http://purl.obolibrary.org/obo/IEV_0000110 IL1 signaling pathway http://purl.obolibrary.org/obo/IEV_0000232 IL-1 signaling (through p38 cascade) http://purl.obolibrary.org/obo/IEV_0000110 IL1 signaling pathway http://purl.obolibrary.org/obo/IEV_0000569 Lck degradation signaling http://purl.obolibrary.org/obo/IEV_0002255 Negative regulation of (Lck activation signaling) http://purl.obolibrary.org/obo/IEV_0000868 p53 degradation signaling http://purl.obolibrary.org/obo/IEV_0000122 Proteasome mediated protein degradation signaling http://purl.obolibrary.org/obo/IEV_0000130 Cyclin E degradation signaling http://purl.obolibrary.org/obo/IEV_0000391 Negative regulation of G1-S-phase transition http://purl.obolibrary.org/obo/IEV_0000566 Syk degradation signaling http://purl.obolibrary.org/obo/IEV_0002257 Negative regulation of (Phosphorylation of Vav by Syk) http://purl.obolibrary.org/obo/IEV_0002219 Cytokine receptor degradation signaling http://purl.obolibrary.org/obo/IEV_0000122 Proteasome mediated protein degradation signaling http://purl.obolibrary.org/obo/IEV_0002230 JAK degradation signaling http://purl.obolibrary.org/obo/IEV_0000122 Proteasome mediated protein degradation signaling http://purl.obolibrary.org/obo/IEV_0002564 Notch degradation signaling http://purl.obolibrary.org/obo/IEV_0000122 Proteasome mediated protein degradation signaling http://purl.obolibrary.org/obo/IEV_0000889 TGF beta receptor I degradation signaling http://purl.obolibrary.org/obo/IEV_0000122 Proteasome mediated protein degradation signaling http://purl.obolibrary.org/obo/IEV_0002188 SnoN degradation signaling http://purl.obolibrary.org/obo/IEV_0002190 Positive regulation of (transcription by R-Smad:Smad4 ) in TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0000561 ZAP-70 and CD3 degradation signaling http://purl.obolibrary.org/obo/IEV_0002254 Negative regulation of (Phosphorylation of Vav by ZAP-70) http://purl.obolibrary.org/obo/IEV_0002231 Binding of SOCS1 and JAK in cytosol http://purl.obolibrary.org/obo/IEV_0000132 Binding of SOCS and JAK in cytosol http://purl.obolibrary.org/obo/IEV_0002242 Dephosphorylation of JAK by SHP-1 in cytosol http://purl.obolibrary.org/obo/IEV_0000146 Dephosphorylation of Jak by PTP in cytosol http://purl.obolibrary.org/obo/IEV_0002244 Dephosphorylation of STAT5 by SHP-1 in cytosol http://purl.obolibrary.org/obo/IEV_0000149 Dephosphorylation of STAT dimer by PTP in cytosol http://purl.obolibrary.org/obo/IEV_0002301 Dephosphorylation of STAT6 by SHP-1 in cytosol http://purl.obolibrary.org/obo/IEV_0000149 Dephosphorylation of STAT dimer by PTP in cytosol http://purl.obolibrary.org/obo/IEV_0002718 Dephosphorylation of STAT5 by SHP-2 in cytosol http://purl.obolibrary.org/obo/IEV_0000149 Dephosphorylation of STAT dimer by PTP in cytosol http://purl.obolibrary.org/obo/IEV_0002245 Negative regulation of (Dimerization of STAT) in JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000150 Negative regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0001747 Negative regulation of EPO signaling pathway http://purl.obolibrary.org/obo/IEV_0001746 Regulation of EPO signaling pathway http://purl.obolibrary.org/obo/IEV_0001750 Negative regulation of Growth hormone signaling pathway (JAK2 STAT5) http://purl.obolibrary.org/obo/IEV_0001749 Regulation of Growth hormone signaling pathway (JAK2 STAT5) http://purl.obolibrary.org/obo/IEV_0001753 Negative regulation of JAK STAT signaling (Angiotensin induced) http://purl.obolibrary.org/obo/IEV_0001752 Regulation of JAK STAT signaling (Angiotensin induced) http://purl.obolibrary.org/obo/IEV_0001756 Negative regulation of TPO signaling pathway (through JAK STAT pathway) http://purl.obolibrary.org/obo/IEV_0001755 Regulation of TPO signaling pathway (through JAK STAT pathway) http://purl.obolibrary.org/obo/IEV_0001767 Negative regulation of JAK STAT pathway by (sumoylation of STAT by PIAS1/3) http://purl.obolibrary.org/obo/IEV_0000150 Negative regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0001843 Negative regulation of (Phosphorylation of cytokine receptor) in JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000150 Negative regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0001845 Negative regulation of (Phosphorylation of STAT) in JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000150 Negative regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0003695 Negative regulation of transcription in JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0001838 Negative regulation of transcription http://purl.obolibrary.org/obo/IEV_0001844 Negative regulation of (Phosphorylation of JAK) in JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000150 Negative regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0003613 Negative regulation of IL13 signaling pathway (JAK1, TYK2, STAT6) http://purl.obolibrary.org/obo/IEV_0003612 Regulation of IL13 signaling pathway (JAK1, TYK2, STAT6) http://purl.obolibrary.org/obo/IEV_0002228 Negative feedback regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000150 Negative regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0002221 Binding of SOCS3 and cytokine receptor in cytosol http://purl.obolibrary.org/obo/IEV_0000152 Binding of SOCS and Cytokine receptor in cytosol http://purl.obolibrary.org/obo/IEV_0002173 Nuclear import of Smad1:Smad4 http://purl.obolibrary.org/obo/IEV_0000158 Nuclear import of R-Smad:Smad4 http://purl.obolibrary.org/obo/IEV_0002174 Complex formation of Smad1 and Smad4 in cytosol http://purl.obolibrary.org/obo/IEV_0000159 Complex formation of R-Smad and Smad4 in cytosol http://purl.obolibrary.org/obo/IEV_0003575 Complex formation of Smad5 and Smad4 in cytosol http://purl.obolibrary.org/obo/IEV_0000159 Complex formation of R-Smad and Smad4 in cytosol http://purl.obolibrary.org/obo/IEV_0003577 Complex formation of Smad2 and Smad4 in cytosol http://purl.obolibrary.org/obo/IEV_0000159 Complex formation of R-Smad and Smad4 in cytosol http://purl.obolibrary.org/obo/IEV_0003578 Complex formation of Smad3 and Smad4 in cytosol http://purl.obolibrary.org/obo/IEV_0000159 Complex formation of R-Smad and Smad4 in cytosol http://purl.obolibrary.org/obo/IEV_0003576 Complex formation of Smad8 and Smad4 in cytosol http://purl.obolibrary.org/obo/IEV_0000159 Complex formation of R-Smad and Smad4 in cytosol http://purl.obolibrary.org/obo/IEV_0000421 Peroxidation of sinapyl alcohol to Lignin (angiosperm and grasses) in cytosol http://purl.obolibrary.org/obo/IEV_0000171 Oxidation in cytosol http://purl.obolibrary.org/obo/IEV_0000407 Oxidation of ferulate in cytosol http://purl.obolibrary.org/obo/IEV_0000171 Oxidation in cytosol http://purl.obolibrary.org/obo/IEV_0000415 Oxidation of 4-coumarate in cytosol http://purl.obolibrary.org/obo/IEV_0000171 Oxidation in cytosol http://purl.obolibrary.org/obo/IEV_0000416 Peroxidation of 4-Coumaryl alcohol to Lignin (grasses) in cytosol http://purl.obolibrary.org/obo/IEV_0000171 Oxidation in cytosol http://purl.obolibrary.org/obo/IEV_0000427 Peroxidation of coniferyl alcohol to Lignin (gymnosperm, angiosperm and grasses) in cytosol http://purl.obolibrary.org/obo/IEV_0000171 Oxidation in cytosol http://purl.obolibrary.org/obo/IEV_0000622 Binding of PIP3 and AKT http://purl.obolibrary.org/obo/IEV_0000174 Binding outside the mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000625 Binding of PIP3 and PDK1 http://purl.obolibrary.org/obo/IEV_0000174 Binding outside the mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000533 Phosphorylation of PIP by PI5K in plasma membrane http://purl.obolibrary.org/obo/IEV_0000198 Phosphorylation in plasma membrane http://purl.obolibrary.org/obo/IEV_0000288 Phosphorylation of PIP2 by PI3K in plasma membrane http://purl.obolibrary.org/obo/IEV_0000198 Phosphorylation in plasma membrane http://purl.obolibrary.org/obo/IEV_0000532 Phosphorylation of PI by PI4K in plasma membrane http://purl.obolibrary.org/obo/IEV_0000198 Phosphorylation in plasma membrane http://purl.obolibrary.org/obo/IEV_0001388 Ubiquitination of TRAF6 by TRAF6 in cytosol http://purl.obolibrary.org/obo/IEV_0000202 Ubiquitination of TRAF6 in cytosol http://purl.obolibrary.org/obo/IEV_0002191 Ubiquitination of SnoN by smurf2 http://purl.obolibrary.org/obo/IEV_0000204 Ubiquitination in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0002183 Proteasome degradation of TGF beta receptor complex by 26S proteasome in plasma membrane http://purl.obolibrary.org/obo/IEV_0000206 Proteasome degradation in plasma membrane http://purl.obolibrary.org/obo/IEV_0000893 Proteasome degradation of TGF beta receptor I by 26S proteasome in plasma membrane http://purl.obolibrary.org/obo/IEV_0000206 Proteasome degradation in plasma membrane http://purl.obolibrary.org/obo/IEV_0003510 Dissociation of Cactus_p and DIF in cytosol http://purl.obolibrary.org/obo/IEV_0000215 Dissociation of NF-kappaB and I-kappaB in cytosol http://purl.obolibrary.org/obo/IEV_0003524 Dissociation of Cactus_p and Dorsal:DIF in cytosol http://purl.obolibrary.org/obo/IEV_0000215 Dissociation of NF-kappaB and I-kappaB in cytosol http://purl.obolibrary.org/obo/IEV_0003532 Dissociation of Cactus_p and Dorsal in cytosol http://purl.obolibrary.org/obo/IEV_0000215 Dissociation of NF-kappaB and I-kappaB in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0000219 Translation http://purl.obolibrary.org/obo/IEV_0000945 Myristoylation in cytosol http://purl.obolibrary.org/obo/IEV_0000222 Myristoylation http://purl.obolibrary.org/obo/IEV_0000947 Myristoylation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000222 Myristoylation http://purl.obolibrary.org/obo/IEV_0002206 Gene expression of IL2 by AP-1 http://purl.obolibrary.org/obo/IEV_0000225 Gene expression of cytokine by AP-1 http://purl.obolibrary.org/obo/IEV_0003381 Phosphorylation of MKK4 by TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0003389 Phosphorylation of MKK by TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0002203 Phosphorylation of MKK4(SEK1) by PKC theta in cytosol http://purl.obolibrary.org/obo/IEV_0000227 Phosphorylation of MKK4/7 by MAPKKK in cytosol http://purl.obolibrary.org/obo/IEV_0002433 Phosphorylation of MKK4 by MEKK1 in cytosol http://purl.obolibrary.org/obo/IEV_0003390 Phosphorylation of MKK by MEKK1 in cytosol http://purl.obolibrary.org/obo/IEV_0002703 Phosphorylation of MKK4 by MEKK4 in cytosol http://purl.obolibrary.org/obo/IEV_0000227 Phosphorylation of MKK4/7 by MAPKKK in cytosol http://purl.obolibrary.org/obo/IEV_0002435 Nuclear import of JNK1_p http://purl.obolibrary.org/obo/IEV_0000229 Nuclear import of JNK_p http://purl.obolibrary.org/obo/IEV_0003380 Phosphorylation of MKK3/6 by TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0003389 Phosphorylation of MKK by TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000760 Inactivation of Rhodopsin in extracellular http://purl.obolibrary.org/obo/IEV_0000245 Inactivation in extracellular http://purl.obolibrary.org/obo/IEV_0002589 Inactivation of Ptc by Hedgehog in extracellular http://purl.obolibrary.org/obo/IEV_0000245 Inactivation in extracellular http://purl.obolibrary.org/obo/IEV_0001396 Activation of MEKK3 by RIP1 in cytosol http://purl.obolibrary.org/obo/IEV_0000257 Activation of MEKK3 by RIP in cytosol http://purl.obolibrary.org/obo/IEV_0001384 Activation of TAK1 by ubiquitinated TRAF6 in cytosol http://purl.obolibrary.org/obo/IEV_0000282 Activation of TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0002432 Activation of TAK1 by TAB1 in cytosol http://purl.obolibrary.org/obo/IEV_0000282 Activation of TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0003459 Activation of TAK1 by IMD in cytosol http://purl.obolibrary.org/obo/IEV_0000282 Activation of TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000530 Phosphorylation of PLC gamma by Syk in cytosol http://purl.obolibrary.org/obo/IEV_0000286 Phosphorylation of PLC gamma by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0001290 Phosphorylation of PLC gamma by Btk in cytosol http://purl.obolibrary.org/obo/IEV_0000286 Phosphorylation of PLC gamma by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000314 Mouse L-cell medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000330 PK-15 medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000348 Jurkat cell medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000352 Human bronchial epithelial cell medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000311 ES cell medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000316 Epidermal keratinocyto medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000323 CHO medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000326 COS-7 medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000328 VERO medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000331 CV-1 medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000306 Animal cell medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000318 Amniocyte medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000363 Human vascular endothelial cell medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000341 Chicken aortic smooth muscle cell medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000310 Neuronal cell medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000335 A549 medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000338 Myeloma medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000342 Fibroblast medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000351 Mesenchymal cell medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000353 Mammary epithelial cell medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000354 Human prostate epithelial cell medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000362 Human vascular smooth muscle medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000327 MDCK medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000324 DG44 medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000343 All-purpose medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000317 Macrophage medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000319 Peripheral blood medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000321 Human hematopoietic cell medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000329 BHK-21 medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000332 WI-38 medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000333 Hybridoma cell medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000334 HEp2 medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000322 Lymphocyte medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000336 BSC-1 medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000320 Bone marrow medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000312 HeLa medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000325 293 medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000349 HL60 medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000315 Hepatocyte medium http://purl.obolibrary.org/obo/IEV_0000293 Medium condition http://purl.obolibrary.org/obo/IEV_0000308 Rat cell medium http://purl.obolibrary.org/obo/IEV_0000306 Animal cell medium http://purl.obolibrary.org/obo/IEV_0000309 Mouse cell medium http://purl.obolibrary.org/obo/IEV_0000306 Animal cell medium http://purl.obolibrary.org/obo/IEV_0001077 Dissociation of E2F-1 and RB_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000390 Dissociation of E2F and RB_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000165 p53 signaling pathway (through p21) http://purl.obolibrary.org/obo/IEV_0001103 p53 signaling pathway http://purl.obolibrary.org/obo/IEV_0001153 Negative regulation of G1-S-phase transition pathway by contact pressure (through p21) http://purl.obolibrary.org/obo/IEV_0000391 Negative regulation of G1-S-phase transition http://purl.obolibrary.org/obo/IEV_0001152 Negative regulation of G1-S-phase transition pathway by contact pressure (through p27) http://purl.obolibrary.org/obo/IEV_0000391 Negative regulation of G1-S-phase transition http://purl.obolibrary.org/obo/IEV_0000432 CoA ligation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000394 CoA ligation http://purl.obolibrary.org/obo/IEV_0003027 CoA + GTP + Succinic acid = Succinyl-CoA + GDP + Orthophosphate( EC:6.2.1.4 ) http://purl.obolibrary.org/obo/IEV_0000394 CoA ligation http://purl.obolibrary.org/obo/IEV_0003097 CoA + ATP + Acetic acid => Acetyl-CoA + AMP + Pyrophosphate( EC:6.2.1.1 ) http://purl.obolibrary.org/obo/IEV_0000394 CoA ligation http://purl.obolibrary.org/obo/IEV_0003119 CoA + ATP + Acetoacetic acid => Acetoacetyl-CoA + AMP + Pyrophosphate( EC:6.2.1.16 ) http://purl.obolibrary.org/obo/IEV_0000394 CoA ligation http://purl.obolibrary.org/obo/IEV_0003217 CoA + ATP + Propanoic acid => Propanoyl-CoA + AMP + Pyrophosphate( EC:6.2.1.1 ) http://purl.obolibrary.org/obo/IEV_0000394 CoA ligation http://purl.obolibrary.org/obo/IEV_0003849 ATP + Propanoic acid = Diphosphate + Propionyladenylate( EC:6.2.1.1 ) http://purl.obolibrary.org/obo/IEV_0000394 CoA ligation http://purl.obolibrary.org/obo/IEV_0003853 ATP + Acetic acid = Pyrophosphate + Acetyl adenylate( EC:6.2.1.1 ) http://purl.obolibrary.org/obo/IEV_0000394 CoA ligation http://purl.obolibrary.org/obo/IEV_0003854 Acetyl adenylate + CoA = AMP + Acetyl-CoA( EC:6.2.1.1 ) http://purl.obolibrary.org/obo/IEV_0000394 CoA ligation http://purl.obolibrary.org/obo/IEV_0000430 CoA ligation in cytosol http://purl.obolibrary.org/obo/IEV_0000394 CoA ligation http://purl.obolibrary.org/obo/IEV_0003850 Propionyladenylate + CoA = AMP + Propanoyl-CoA( EC:6.2.1.1 ) http://purl.obolibrary.org/obo/IEV_0000394 CoA ligation http://purl.obolibrary.org/obo/IEV_0002942 CoA + ATP + Succinic acid = Succinyl-CoA + ADP + Orthophosphate( EC:6.2.1.5 ) http://purl.obolibrary.org/obo/IEV_0000394 CoA ligation http://purl.obolibrary.org/obo/IEV_0003048 CoA + ATP + Butanoic acid => Butanoyl-CoA + AMP + Pyrophosphate( EC:6.2.1.2 ) http://purl.obolibrary.org/obo/IEV_0000394 CoA ligation http://purl.obolibrary.org/obo/IEV_0000411 Translocation of Bad from the cytosol to the mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000412 Translocation from cytosol to mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000954 Translocation of NOXA from the cytosol to the mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000412 Translocation from cytosol to mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000958 Translocation of PUMA from cytosol to the mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000412 Translocation from cytosol to mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000966 Translocation of Bmf from the cytosol to the mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000412 Translocation from cytosol to mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000962 Translocation of Bim from the cytosol to the mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000412 Translocation from cytosol to mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000444 Translocation of Bax from the cytosol to the mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000412 Translocation from cytosol to mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000948 Translocation of Bid from the cytosol to the mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000412 Translocation from cytosol to mitochondria membrane http://purl.obolibrary.org/obo/IEV_0001488 Dephosphorylation of PIP3 by PTEN in plasma membrane http://purl.obolibrary.org/obo/IEV_0000414 Dephosphorylation in plasma membrane http://purl.obolibrary.org/obo/IEV_0000419 O-methyltransferase of caffeoyl-CoA by CCR in cytosol http://purl.obolibrary.org/obo/IEV_0000435 Transmethylation in cytosol http://purl.obolibrary.org/obo/IEV_0000425 O-methyl-transfer of caffeic acid by OMT in cytosol http://purl.obolibrary.org/obo/IEV_0000435 Transmethylation in cytosol http://purl.obolibrary.org/obo/IEV_0000439 Hydroxylation in the unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000437 Hydroxylation http://purl.obolibrary.org/obo/IEV_0000438 Hydroxylation in the cytosol http://purl.obolibrary.org/obo/IEV_0000437 Hydroxylation http://purl.obolibrary.org/obo/IEV_0000420 Hydroxylation of trans-cinnamate by C4H in the cytosol http://purl.obolibrary.org/obo/IEV_0000438 Hydroxylation in the cytosol http://purl.obolibrary.org/obo/IEV_0001667 Bcl-2/Bcl-xL inactivation signaling http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0000780 PKA activation signaling http://purl.obolibrary.org/obo/IEV_0001988 cAMP mediated signaling http://purl.obolibrary.org/obo/IEV_0000929 Caspase8/10 activation signaling http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0001807 TCF phosphorylation signaling http://purl.obolibrary.org/obo/IEV_0001676 Negative regulation of Wnt signaling pathway http://purl.obolibrary.org/obo/IEV_0002022 Adenylate cyclase inactivation signaling http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0001301 Small GTPase activation signaling http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0001589 Src family activation signaling http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0001590 Src family inactivation signaling http://purl.obolibrary.org/obo/IEV_0000559 Negative regulation of Src family activation signaling http://purl.obolibrary.org/obo/IEV_0002072 Raf activation signaling http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0002079 Rap1 activation signaling http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0002089 Rap1 inactivation signaling http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0002302 Syk activation signaling http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0001379 IKK activation signaling http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0000848 RalGDS activation signaling (through Grb2 and Sos) http://purl.obolibrary.org/obo/IEV_0001258 Ras mediated signaling http://purl.obolibrary.org/obo/IEV_0001003 Caspase9 activation signaling http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0001006 Caspase3/6/7 activation signaling (through mitochondria) http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0000671 G alpha-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0000669 Negative regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0001302 Calcium ion dependent protein activation signaling http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0001484 AKT(PKB) activation signaling http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0001227 PI3K activation signaling http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0001030 Apoptotic factor inactivation signaling http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0001744 GSK3beta inactivation signaling http://purl.obolibrary.org/obo/IEV_0001677 Positive regulation of Wnt signaling pathway http://purl.obolibrary.org/obo/IEV_0001013 Caspase3/6/7 activation signaling (not through mitochondria) http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0002012 G alpha GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0000458 Protein activation/inactivation signaling http://purl.obolibrary.org/obo/IEV_0000229 Nuclear import of JNK_p http://purl.obolibrary.org/obo/IEV_0000480 Nuclear import of MAPK (through MAPKKK cascade) http://purl.obolibrary.org/obo/IEV_0000466 Nuclear import of ERK_p http://purl.obolibrary.org/obo/IEV_0000480 Nuclear import of MAPK (through MAPKKK cascade) http://purl.obolibrary.org/obo/IEV_0000237 Nuclear import of p38_p http://purl.obolibrary.org/obo/IEV_0000480 Nuclear import of MAPK (through MAPKKK cascade) http://purl.obolibrary.org/obo/IEV_0000593 Autophosphorylation of FAK in cytosol http://purl.obolibrary.org/obo/IEV_0000481 Autophosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001607 Autophosphorylation of Src family and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0000481 Autophosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003493 Autophosphorylation of Pelle in cytosol http://purl.obolibrary.org/obo/IEV_0000481 Autophosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003768 Autophosphorylation of Fu in cytosol http://purl.obolibrary.org/obo/IEV_0000481 Autophosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003890 Autophosphorylation of PAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000481 Autophosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001390 Autophosphorylation of TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000481 Autophosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001393 Binding of calcium ion and cPKC and active conformational change of cPKC in cytosol http://purl.obolibrary.org/obo/IEV_0000483 Binding of calcium ion and PKC and active conformational change of PKC in cytosol http://purl.obolibrary.org/obo/IEV_0001377 Transcription of IL-2 by NF-kappaB in nucleus http://purl.obolibrary.org/obo/IEV_0001308 Transcription by NF-kappaB in nucleus http://purl.obolibrary.org/obo/IEV_0003752 Translocation of Smo from endosome to plasma membrane http://purl.obolibrary.org/obo/IEV_0000505 Translocation from endosome to plasma membrane http://purl.obolibrary.org/obo/IEV_0000503 Translocation of insulin receptor from the endosome to plasma membrane http://purl.obolibrary.org/obo/IEV_0000505 Translocation from endosome to plasma membrane http://purl.obolibrary.org/obo/IEV_0000068 Translocation of Notch (NIC) from plasma membrane to cytosol http://purl.obolibrary.org/obo/IEV_0000508 Translocation from plasma membrane to cytosol http://purl.obolibrary.org/obo/IEV_0002179 Translocation of TRAF6 to cytosol http://purl.obolibrary.org/obo/IEV_0000508 Translocation from plasma membrane to cytosol http://purl.obolibrary.org/obo/IEV_0000497 Internalisation of the insulin receptor http://purl.obolibrary.org/obo/IEV_0001505 Receptor internalization http://purl.obolibrary.org/obo/IEV_0002251 Negative regulation of (Phosphorylation of ZAP-70 by Lck_PY) http://purl.obolibrary.org/obo/IEV_0002249 Negative regulation of CD4 T cell receptor signaling (through Ras and Erk cascade) http://purl.obolibrary.org/obo/IEV_0002252 Negative regulation of (Phosphorylation of PIP2 by PI3K) http://purl.obolibrary.org/obo/IEV_0002249 Negative regulation of CD4 T cell receptor signaling (through Ras and Erk cascade) http://purl.obolibrary.org/obo/IEV_0002253 Negative regulation of (Phosphorylation of LAT by ZAP-70) http://purl.obolibrary.org/obo/IEV_0002249 Negative regulation of CD4 T cell receptor signaling (through Ras and Erk cascade) http://purl.obolibrary.org/obo/IEV_0002255 Negative regulation of (Lck activation signaling) http://purl.obolibrary.org/obo/IEV_0002249 Negative regulation of CD4 T cell receptor signaling (through Ras and Erk cascade) http://purl.obolibrary.org/obo/IEV_0002254 Negative regulation of (Phosphorylation of Vav by ZAP-70) http://purl.obolibrary.org/obo/IEV_0002249 Negative regulation of CD4 T cell receptor signaling (through Ras and Erk cascade) http://purl.obolibrary.org/obo/IEV_0002257 Negative regulation of (Phosphorylation of Vav by Syk) http://purl.obolibrary.org/obo/IEV_0002249 Negative regulation of CD4 T cell receptor signaling (through Ras and Erk cascade) http://purl.obolibrary.org/obo/IEV_0002256 Negative regulation of (Fyn activation signaling) http://purl.obolibrary.org/obo/IEV_0002249 Negative regulation of CD4 T cell receptor signaling (through Ras and Erk cascade) http://purl.obolibrary.org/obo/IEV_0000173 Negative regulation of Fas signaling pathway http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000545 Positive regulation of Fas signaling pathway http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000391 Negative regulation of G1-S-phase transition http://purl.obolibrary.org/obo/IEV_0001404 Negative regulation of cell cycle process http://purl.obolibrary.org/obo/IEV_0000547 Positive regulation of G1-S-phase transition http://purl.obolibrary.org/obo/IEV_0001405 Positive regulation of cell cycle process http://purl.obolibrary.org/obo/IEV_0001748 Positive regulation of EPO signaling pathway http://purl.obolibrary.org/obo/IEV_0001746 Regulation of EPO signaling pathway http://purl.obolibrary.org/obo/IEV_0001751 Positive regulation of Growth hormone signaling pathway (JAK2 STAT5) http://purl.obolibrary.org/obo/IEV_0001749 Regulation of Growth hormone signaling pathway (JAK2 STAT5) http://purl.obolibrary.org/obo/IEV_0001754 Positive regulation of JAK STAT signaling (Angiotensin induced) http://purl.obolibrary.org/obo/IEV_0001752 Regulation of JAK STAT signaling (Angiotensin induced) http://purl.obolibrary.org/obo/IEV_0001757 Positive regulation of TPO signaling pathway (through JAK STAT pathway) http://purl.obolibrary.org/obo/IEV_0001755 Regulation of TPO signaling pathway (through JAK STAT pathway) http://purl.obolibrary.org/obo/IEV_0002246 Positive regulation of (Transcription of SOCS by STAT dimer) in JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000551 Positive regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000553 Positive regulation of NF-kappaB signaling (cytoplasmic sequestering) http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000188 Negative regulation of NF-kappaB signaling (cytoplasmic sequestering) http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000287 Negative regulation of PLC gamma signaling (through LAT) http://purl.obolibrary.org/obo/IEV_0001797 Negative regulation of CD4 T cell receptor signaling (through PLC gamma, calcineurin and NF-AT) http://purl.obolibrary.org/obo/IEV_0000555 Positive regulation of PLC gamma signaling (through LAT) http://purl.obolibrary.org/obo/IEV_0001798 Positive regulation of CD4 T cell receptor signaling (through PLC gamma, calcineurin and NF-AT) http://purl.obolibrary.org/obo/IEV_0002447 Activation of Raf1 by Ras-GTP in cytosol http://purl.obolibrary.org/obo/IEV_0000608 Activation of Raf by Ras-GTP in cytosol http://purl.obolibrary.org/obo/IEV_0000611 Negative regulation of integrin signaling pathway http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000612 Positive regulation of integrin signaling pathway http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000655 Regulation of Integrin signaling pathway (through Rho) http://purl.obolibrary.org/obo/IEV_0000610 Regulation of integrin signaling pathway http://purl.obolibrary.org/obo/IEV_0000656 Negative regulation of Integrin signaling pathway (through Rho) http://purl.obolibrary.org/obo/IEV_0000655 Regulation of Integrin signaling pathway (through Rho) http://purl.obolibrary.org/obo/IEV_0000408 Phosphorylation of AKT by PDK1 http://purl.obolibrary.org/obo/IEV_0002415 Phosphorylation of Akt by protein kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000403 Phosphorylation of Bad by AKT_p http://purl.obolibrary.org/obo/IEV_0000624 Phosphorylation outside the mitochondria membrane http://purl.obolibrary.org/obo/IEV_0003903 Phosphorylation of Raf1 by PAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000629 Phosphorylation of MAPKKK by PAK in cytosol http://purl.obolibrary.org/obo/IEV_0000659 Rac/Cdc42-PAK-MLCK signaling http://purl.obolibrary.org/obo/IEV_0001259 Rac mediated signaling http://purl.obolibrary.org/obo/IEV_0000777 Dissociation of G alpha o-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000664 Dissociation of G alpha-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000719 Dissociation of G alpha i-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000664 Dissociation of G alpha-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000721 Dissociation of G alpha s-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000664 Dissociation of G alpha-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000727 Dissociation of G alpha t-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000664 Dissociation of G alpha-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000749 Dissociation of G alpha q-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000664 Dissociation of G alpha-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0001924 Dissociation of phosphatidylserine and PKC in plasma membrane http://purl.obolibrary.org/obo/IEV_0000665 Dissociation in plasma membrane http://purl.obolibrary.org/obo/IEV_0001242 Dissociation of magnesium ion and NMDA receptor in plasma membrane http://purl.obolibrary.org/obo/IEV_0000665 Dissociation in plasma membrane http://purl.obolibrary.org/obo/IEV_0000732 Regulation of heterotrimeric GPCR signaling pathway (through photon, rhodopsin, G alpha t and PDE) http://purl.obolibrary.org/obo/IEV_0000668 Regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0001695 Regulation of endothelin receptor signaling http://purl.obolibrary.org/obo/IEV_0000668 Regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0002005 Regulation of heterotrimeric GPCR signaling pathway (through G alpha s, cholera toxin, adenylate cyclase and cAMP) http://purl.obolibrary.org/obo/IEV_0000668 Regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0000670 Positive regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000731 Regulation of heterotrimeric GPCR signaling pathway (through G alpha s) http://purl.obolibrary.org/obo/IEV_0000668 Regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0000751 Regulation of heterotrimeric GPCR signaling pathway (through G alpha q and PLC beta) http://purl.obolibrary.org/obo/IEV_0000668 Regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0000730 Regulation of heterotrimeric GPCR signaling pathway (through G alpha i) http://purl.obolibrary.org/obo/IEV_0000668 Regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0000669 Negative regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000851 Hydrolysis of GTP by Rac in cytosol http://purl.obolibrary.org/obo/IEV_0000680 Hydrolysis of GTP by small GTPase in cytosol http://purl.obolibrary.org/obo/IEV_0000705 Hydrolysis of GTP by Ras in cytosol http://purl.obolibrary.org/obo/IEV_0000680 Hydrolysis of GTP by small GTPase in cytosol http://purl.obolibrary.org/obo/IEV_0003634 Hydrolysis of GTP by Rheb and TSC2 in cytosol http://purl.obolibrary.org/obo/IEV_0000680 Hydrolysis of GTP by small GTPase in cytosol http://purl.obolibrary.org/obo/IEV_0000713 Binding of G alpha s-GTP-ADPrib and adenylate cyclase in cytosol http://purl.obolibrary.org/obo/IEV_0000686 Binding of G alpha s-GTP and adenylate cyclase in cytosol http://purl.obolibrary.org/obo/IEV_0002419 Binding of G alpha s-GTP and adenylate cyclase type V in cytosol http://purl.obolibrary.org/obo/IEV_0000686 Binding of G alpha s-GTP and adenylate cyclase in cytosol http://purl.obolibrary.org/obo/IEV_0002420 Hydrolysis of ATP to cAMP by adenylate cyclase type V in cytosol http://purl.obolibrary.org/obo/IEV_0000687 Hydrolysis of ATP to cAMP by adenylate cyclase in cytosol http://purl.obolibrary.org/obo/IEV_0002402 Dissociation of AT1R, G alpha s-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000721 Dissociation of G alpha s-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0002418 Dissociation of D1-like receptor, G alpha s-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000721 Dissociation of G alpha s-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0003432 Dissociation of Adenosine A2A receptor, G alpha s-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000721 Dissociation of G alpha s-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000734 Positive regulation of heterotrimeric GPCR signaling pathway (through photon, rhodopsin, G alpha t and PDE) http://purl.obolibrary.org/obo/IEV_0000670 Positive regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0000733 Negative regulation of heterotrimeric GPCR signaling pathway (through photon, rhodopsin, G alpha t and PDE) http://purl.obolibrary.org/obo/IEV_0000669 Negative regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0000770 Channel opening/closing in the ER membrane http://purl.obolibrary.org/obo/IEV_0000767 Channel opening/closing http://purl.obolibrary.org/obo/IEV_0000762 Channel opening/closing in the plasma membrane http://purl.obolibrary.org/obo/IEV_0000767 Channel opening/closing http://purl.obolibrary.org/obo/IEV_0000765 Dissociation of IP3 and IP3R and IP3R closing http://purl.obolibrary.org/obo/IEV_0001032 Dissociation outside the ER membrane http://purl.obolibrary.org/obo/IEV_0000272 Binding of IP3 and IP3R and IP3R opening http://purl.obolibrary.org/obo/IEV_0001037 Binding outside the ER membrane http://purl.obolibrary.org/obo/IEV_0000218 Gene expression of cytokine by NF-kappaB http://purl.obolibrary.org/obo/IEV_0000783 Gene expression by NF-kappaB http://purl.obolibrary.org/obo/IEV_0003525 Expression of antimicrobial peptide by DIF:Dorsal http://purl.obolibrary.org/obo/IEV_0000783 Gene expression by NF-kappaB http://purl.obolibrary.org/obo/IEV_0003533 Expression of antimicrobial peptide by Dorsal http://purl.obolibrary.org/obo/IEV_0000783 Gene expression by NF-kappaB http://purl.obolibrary.org/obo/IEV_0000838 Gene expression of anti-apoptotic gene by NF-kappaB http://purl.obolibrary.org/obo/IEV_0000783 Gene expression by NF-kappaB http://purl.obolibrary.org/obo/IEV_0003511 Expression of antimicrobial peptide by DIF http://purl.obolibrary.org/obo/IEV_0000783 Gene expression by NF-kappaB http://purl.obolibrary.org/obo/IEV_0003420 Gene expression of c-FLIP by NF-kappaB http://purl.obolibrary.org/obo/IEV_0000783 Gene expression by NF-kappaB http://purl.obolibrary.org/obo/IEV_0003464 Expression of antimicrobial peptide by Relish http://purl.obolibrary.org/obo/IEV_0000783 Gene expression by NF-kappaB http://purl.obolibrary.org/obo/IEV_0000786 Negative regulation of Toll-like receptor pathway (through LPS, TLR4, MyD88, IRAK-1, TAK1 and IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0001673 Negative regulation of Toll-like receptor pathway http://purl.obolibrary.org/obo/IEV_0000787 Positive regulation of Toll-like receptor pathway (through LPS, TLR4, MyD88, IRAK-1, TAK1 and IKK- NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0001674 Positive regulation of Toll-like receptor pathway http://purl.obolibrary.org/obo/IEV_0000794 Binding of fatty acid and PPAR in cytosol http://purl.obolibrary.org/obo/IEV_0000790 Binding of ligand and PPAR in cytosol http://purl.obolibrary.org/obo/IEV_0000822 Negative regulation of PDGF signaling pathway (through Grb2, Sos, Ras and Erk cascade) http://purl.obolibrary.org/obo/IEV_0001671 Negative regulation of PDGF receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0000823 Positive regulation of PDGF signaling pathway (through Grb2, Sos, Ras and Erk cascade) http://purl.obolibrary.org/obo/IEV_0001672 Positive regulation of PDGF signaling pathway http://purl.obolibrary.org/obo/IEV_0000860 Regulation of RTK signaling pathway (through Grb2, Sos, Ras, RalGDS, Ral and PLD) http://purl.obolibrary.org/obo/IEV_0000834 Regulation of RTK signaling pathway http://purl.obolibrary.org/obo/IEV_0000835 Negative regulation of RTK signaling pathway http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000853 Regulation of RTK signaling pathway (through Grb2, Sos, Ras, RalGDS, Ral, RalBP1 and Rac-GTP hydrolysis signaling) http://purl.obolibrary.org/obo/IEV_0000834 Regulation of RTK signaling pathway http://purl.obolibrary.org/obo/IEV_0000836 Positive regulation of RTK signaling pathway http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001406 Regulation of PDGF signaling pathway http://purl.obolibrary.org/obo/IEV_0000834 Regulation of RTK signaling pathway http://purl.obolibrary.org/obo/IEV_0000854 Negative regulation of RTK signaling pathway (through Grb2, Sos, Ras, RalGDS, Ral, RalBP1 and Rac-GTP hydrolysis signaling) http://purl.obolibrary.org/obo/IEV_0000853 Regulation of RTK signaling pathway (through Grb2, Sos, Ras, RalGDS, Ral, RalBP1 and Rac-GTP hydrolysis signaling) http://purl.obolibrary.org/obo/IEV_0001671 Negative regulation of PDGF receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001406 Regulation of PDGF signaling pathway http://purl.obolibrary.org/obo/IEV_0000841 Positive regulation of PDGF signaling pathway (through Grb2, Sos, Ras, PI3K, AKT and IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0001672 Positive regulation of PDGF signaling pathway http://purl.obolibrary.org/obo/IEV_0000840 Negative regulation of PDGF signaling pathway (through Grb2, Sos, Ras, PI3K, AKT and IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0001671 Negative regulation of PDGF receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0003697 Binding of TGF alpha and EGFR in extracellular http://purl.obolibrary.org/obo/IEV_0000842 Binding of RTK-ligand and RTK in extracellular http://purl.obolibrary.org/obo/IEV_0002440 Binding of EGF and EGFR in extracellular http://purl.obolibrary.org/obo/IEV_0000842 Binding of RTK-ligand and RTK in extracellular http://purl.obolibrary.org/obo/IEV_0002453 Binding of HGF and Met in extracellular http://purl.obolibrary.org/obo/IEV_0000842 Binding of RTK-ligand and RTK in extracellular http://purl.obolibrary.org/obo/IEV_0002478 Binding of VEGF and KDR in extracellular http://purl.obolibrary.org/obo/IEV_0000842 Binding of RTK-ligand and RTK in extracellular http://purl.obolibrary.org/obo/IEV_0002486 Binding of FGF and FGFR in extracellular http://purl.obolibrary.org/obo/IEV_0000842 Binding of RTK-ligand and RTK in extracellular http://purl.obolibrary.org/obo/IEV_0003551 Binding of IGF-1 and IGF-1 receptor in extracellular http://purl.obolibrary.org/obo/IEV_0000842 Binding of RTK-ligand and RTK in extracellular http://purl.obolibrary.org/obo/IEV_0002470 Binding of NGF and TRK in extracellular http://purl.obolibrary.org/obo/IEV_0000842 Binding of RTK-ligand and RTK in extracellular http://purl.obolibrary.org/obo/IEV_0000812 Binding of PDGF and PDGF receptor in extracellular http://purl.obolibrary.org/obo/IEV_0000842 Binding of RTK-ligand and RTK in extracellular http://purl.obolibrary.org/obo/IEV_0002442 Autophosphorylation of EGFR in plasma membrane http://purl.obolibrary.org/obo/IEV_0000843 Autophosphorylation of RTK in plasma membrane http://purl.obolibrary.org/obo/IEV_0002455 Autophosphorylation of Met in plasma membrane http://purl.obolibrary.org/obo/IEV_0000843 Autophosphorylation of RTK in plasma membrane http://purl.obolibrary.org/obo/IEV_0002472 Autophosphorylation of TRK in plasma membrane http://purl.obolibrary.org/obo/IEV_0000843 Autophosphorylation of RTK in plasma membrane http://purl.obolibrary.org/obo/IEV_0002480 Autophosphorylation of KDR in plasma membrane http://purl.obolibrary.org/obo/IEV_0000843 Autophosphorylation of RTK in plasma membrane http://purl.obolibrary.org/obo/IEV_0002488 Autophosphorylation of FGFR in plasma membrane http://purl.obolibrary.org/obo/IEV_0000843 Autophosphorylation of RTK in plasma membrane http://purl.obolibrary.org/obo/IEV_0003552 Autophosphorylation of IGF-1 receptor in plasma membrane http://purl.obolibrary.org/obo/IEV_0000843 Autophosphorylation of RTK in plasma membrane http://purl.obolibrary.org/obo/IEV_0000814 Autophosphorylation of PDGF receptor in plasma membrane http://purl.obolibrary.org/obo/IEV_0000843 Autophosphorylation of RTK in plasma membrane http://purl.obolibrary.org/obo/IEV_0000855 Positive regulation of RTK signaling pathway (through Grb2, Sos, Ras, RalGDS, Ral, RalBP1 and Rac-GTP hydrolysis signaling) http://purl.obolibrary.org/obo/IEV_0000836 Positive regulation of RTK signaling pathway http://purl.obolibrary.org/obo/IEV_0000877 Negative regulation of TGF beta super family signaling pathway (through p38 cascade) http://purl.obolibrary.org/obo/IEV_0000880 Negative regulation of TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0002505 Negative regulation of BMP2 signaling pathway (through TAK1) http://purl.obolibrary.org/obo/IEV_0002504 Regulation of BMP2 signaling pathway (through TAK1) http://purl.obolibrary.org/obo/IEV_0002502 Negative regulation of BMP2 signaling pathway (through Smad) http://purl.obolibrary.org/obo/IEV_0002501 Regulation of BMP2 signaling pathway (through Smad) http://purl.obolibrary.org/obo/IEV_0002503 Positive regulation of BMP2 signaling pathway (through Smad) http://purl.obolibrary.org/obo/IEV_0002501 Regulation of BMP2 signaling pathway (through Smad) http://purl.obolibrary.org/obo/IEV_0002506 Positive regulation of BMP2 signaling pathway (through TAK1) http://purl.obolibrary.org/obo/IEV_0002504 Regulation of BMP2 signaling pathway (through TAK1) http://purl.obolibrary.org/obo/IEV_0001398 Nuclear export of mRNA (Smad7) http://purl.obolibrary.org/obo/IEV_0000900 Nuclear export of mRNA (I-Smad) http://purl.obolibrary.org/obo/IEV_0000908 Translation of Smad7 in cytosol http://purl.obolibrary.org/obo/IEV_0000902 Translation of I-Smad in cytosol http://purl.obolibrary.org/obo/IEV_0000900 Nuclear export of mRNA (I-Smad) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0001655 Nuclear export of mRNA (Bid) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0001656 Nuclear export of mRNA (NOXA) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0001657 Nuclear export of mRNA (PUMA) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0002210 Nuclear export of mRNA (cytokine) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0003349 Nuclear export of mRNA (Sef) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0003355 Nuclear export of mRNA (Mkp3) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0003688 Nuclear export of mRNA (vvl) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0003704 Nuclear export of mRNA (Mae) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0003718 Nuclear export of mRNA (Sprouty) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0003783 Nuclear export of mRNA (FGF receptor) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0003787 Nuclear export of mRNA (SRF) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0003865 Nuclear export of mRNA (CKI) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0001116 Nuclear export of mRNA (GADD45) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0001119 Nuclear export of mRNA (Mdm2) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0003723 Nuclear export of mRNA (Argos) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0001654 Nuclear export of mRNA (BAK) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0002105 Nuclear export of mRNA (SOCS) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0001128 Nuclear export of mRNA (BAX) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0003422 Nuclear export of mRNA (c-FLIP) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0003727 Nuclear export of mRNA (Kek) http://purl.obolibrary.org/obo/IEV_0000909 Nuclear export of mRNA http://purl.obolibrary.org/obo/IEV_0003012 D-Sedoheptulose 7-phosphate + D-Glyceraldehyde 3-phosphate = D-Erythrose 4-phosphate + beta-D-Fructose 6-phosphate( EC:2.2.1.2 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002824 L-Alanine + 2-Oxo-glutaric acid = Pyruvic acid + L-Glutamic acid( EC:2.6.1.2 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002901 (S)-3-Hydroxy-3-methyl-glutaryl-CoA + CoA => Acetyl-CoA + Acetoacetyl-CoA + H2O( EC:2.3.3.10 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002945 Choloyl-CoA + Taurine = CoA + Taurocholic acid( EC:2.3.1.65 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002817 L-2-Amino-adipic acid + 2-Oxo-glutaric acid = 2-Oxo-adipic acid + L-Glutamic acid( EC:2.6.1.39 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002749 Succinyl-CoA + 3-oxo acid = succinate + 3-oxoacyl-CoA( EC:2.8.3.5 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002739 Acyl-CoA + Acetyl-CoA = CoA + 3-Oxoacyl-CoA( EC:2.3.1.16 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002743 Phosphoenol-pyruvic acid + N-acyl-D-mannosamine 6-phosphate + H2O = N-acylneuraminate 9-phosphate + Orthophosphate( EC:2.5.1.57 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002767 L-Arginine + Glycine = L-Ornithine + Guanidino-acetic acid( EC:2.1.4.1 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002784 2-Oxo-glutaric acid + L-Cysteine-sulfinic acid = L-Glutamic acid + 3-Sulfinyl-pyruvic acid( EC:2.6.1.1 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002796 Tetrahydrofolate + L-Serine = 5,10-Methylene-tetrahydro-folic acid + Glycine + H2O( EC:2.1.2.1 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002807 L-Aspartic acid + Carbamoyl phosphate => N-Carbamoyl-L-aspartic acid + Orthophosphate( EC:2.1.3.2 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002816 5-Formimino-tetrahydro-folic acid + L-Glutamic acid = Tetrahydrofolate + N-Formimino-L-glutamic acid( EC:2.1.2.5 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002834 2-Oxo-glutaric acid + L-erythro-4-Hydroxy-glutamic acid = L-Glutamic acid + D-4-Hydroxy-2-oxo-glutaric acid( EC:2.6.1.1 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002842 2-Oxo-glutaric acid + L-Cysteine = DL-Glutamic acid + 3-Mercapto-pyruvic acid( EC:2.6.1.1 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002847 2-Oxo-glutaric acid + L-Cysteic acid = L-Glutamic acid + 3-Sulfo-pyruvic acid( EC:2.6.1.1 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002873 Farnesyl diphosphate + Isopentenyl diphosphate = Geranyl-geranyl diphosphate + Pyrophosphate( EC:2.5.1.29 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002878 L-Glutamine + D-Fructose 6-phosphate = L-Glutamic acid + D-Glucosamine 6-phosphate( EC:2.6.1.16 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002910 Succinyl-CoA + Enzyme N6-(dihydrolipoyl)lysine = CoA + [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine( EC:2.3.1.61 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002951 2-Oxo acid + L-Ornithine = L-Amino acid + L-Glutamate 5-semialdehyde( EC:2.6.1.13 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002981 L-Serine + Pyruvic acid = Hydroxy-pyruvic acid + L-Alanine( EC:2.6.1.51 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002986 N-Acetyl-D-mannosamine + Phosphoenol-pyruvic acid + H2O => N-Acetyl-neuraminic acid + Orthophosphate( EC:2.5.1.56 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002989 beta-D-Fructose 6-phosphate + D-Glyceraldehyde 3-phosphate = D-Erythrose 4-phosphate + D-Xylulose 5-phosphate( EC:2.2.1.1 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002995 2-Oxo-glutaric acid + 4-Amino-butanoic acid = L-Glutamic acid + Succinate semialdehyde( EC:2.6.1.19 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002997 L-Alanine + Glyoxylic acid = Pyruvic acid + Glycine( EC:2.6.1.44 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002998 2-Oxo-glutaric acid + L-Valine = L-Glutamic acid + 3-Methyl-2-oxo-butanoic acid( EC:2.6.1.42 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003004 2-Oxo-glutaric acid + L-Aspartic acid = L-Glutamic acid + Oxaloacetic acid( EC:2.6.1.1 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003023 N6-Acetyl-L-lysine + 2-Oxo-glutaric acid = 6-Acetamido-2-oxo-hexanoic acid + L-Glutamic acid( EC:2.6.1.65 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003041 2-Oxo-glutaric acid + L-Leucine = L-Glutamic acid + 4-Methyl-2-oxo-pentanoic acid( EC:2.6.1.42 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003045 2-Oxo-glutaric acid + L-Phenylalanine = L-Glutamic acid + Phenyl-pyruvic acid( EC:2.6.1.5 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003054 Dihydro-lipoylprotein + 5,10-Methylene-tetrahydro-folic acid + NH3 => S-Aminomethyl-dihydro-lipoylprotein + Tetrahydrofolate( EC:2.1.2.10 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003072 4 Porphobilinogen + H2O => Hydroxy-methylbilane + 4 NH3( EC:2.5.1.61 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003079 Acyl-CoA + Cholesterol = CoA + Cholesterol ester( EC:2.3.1.26 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003085 2-Oxo-glutaric acid + L-Tyrosine = L-Glutamic acid + 4-Hydroxy-phenyl-pyruvic acid( EC:2.6.1.5 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003087 Glycine + Succinyl-CoA => CO2 + 5-Amino-4-oxo-pentanoic acid + CoA( EC:2.3.1.37 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003096 S-Adenosylmethioninamine + Spermidine => 5'-Methylthio-adenosine + Spermine( EC:2.5.1.22 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003136 Isopentenyl diphosphate + Geranyl diphosphate => Farnesyl diphosphate + Pyrophosphate( EC:2.5.1.10 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003163 2-Oxo-glutaric acid + L-O-Phospho-serine = L-Glutamic acid + 3-Phospho-hydroxy-pyruvic acid( EC:2.6.1.52 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003284 2-Oxo-glutaric acid + O-Phospho-4-hydroxy-L-threonine = L-Glutamic acid + 2-Oxo-3-hydroxy-4-phospho-butanoic acid( EC:2.6.1.52 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003285 Isopentenyl diphosphate + Dimethylallyl diphosphate => Geranyl diphosphate + Pyrophosphate( EC:2.5.1.1 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003295 3-Mercapto-pyruvic acid + Sulfite => Pyruvic acid + Thiosulfate( EC:2.8.1.2 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003325 2-Oxo-glutaric acid + L-Phenylalanine = L-Glutamic acid + Phenyl-pyruvic acid( EC:2.6.1.1 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003848 L-Glutamate + Glyoxylic acid = 2-Oxo-glutaric acid + Glycine( EC:2.6.1.44 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003164 ATP + CoA + Citric acid = ADP + Acetyl-CoA + Oxaloacetic acid + Orthophosphate( EC:2.3.3.8 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0000921 Isoprenylation http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003841 2-Oxo-glutaric acid + N2-Succinyl-L-ornithine = L-Glutamic acid + N-Succinyl-L-glutamate 5-semialdehyde( EC:2.6.1.81 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003273 ATP + L-Methionine + H2O => S-Adenosyl-L-methionine + Pyrophosphate + Orthophosphate( EC:2.5.1.6 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003243 S-Adenosylmethioninamine + Putrescine => 5'-Methylthio-adenosine + Spermidine( EC:2.5.1.16 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0000607 Transference in cytosol http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003169 2 Farnesyl diphosphate + NADPH + H+ => NADP+ + Squalene + 2 Pyrophosphate( EC:2.5.1.21 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002771 2 Farnesyl diphosphate => Presqualene diphosphate + Pyrophosphate( EC:2.5.1.21 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002741 (5-L-glutamyl)-peptide + Amino acid = peptide + 5-L-glutamyl amino acid( EC:2.3.2.2 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002893 Acetyl-CoA + Oxaloacetic acid + H2O => CoA + Citric acid( EC:2.3.3.1 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002846 D-Sedoheptulose 7-phosphate + D-Glyceraldehyde 3-phosphate = D-Ribose 5-phosphate + D-Xylulose 5-phosphate( EC:2.2.1.1 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002766 2-Oxo-glutaric acid + beta-Alanine = L-Glutamic acid + Malonate semialdehyde( EC:2.6.1.19 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003209 L-Ornithine + Carbamoyl phosphate => L-Citrulline + Orthophosphate( EC:2.1.3.3 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003162 2-Oxo-glutaric acid + L-Isoleucine = L-Glutamic acid + (S)-3-Methyl-2-oxopentanoic acid( EC:2.6.1.42 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0002939 3-Hydroxy-N6,N6,N6-trimethyl-L-lysine => 4-Trimethyl-ammonio-butanal + Glycine( EC:4.1.2.- ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0000712 Transference in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0003222 NADPH + Presqualene diphosphate + H+ => NADP+ + Squalene + Pyrophosphate( EC:2.5.1.21 ) http://purl.obolibrary.org/obo/IEV_0000913 Transference http://purl.obolibrary.org/obo/IEV_0001062 Geranylgeranylation in cytosol http://purl.obolibrary.org/obo/IEV_0000920 Geranylgeranylation http://purl.obolibrary.org/obo/IEV_0001061 Geranylgeranylation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000920 Geranylgeranylation http://purl.obolibrary.org/obo/IEV_0000981 Activation of Bak by Bid in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000979 Activation in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000994 Hydrolysis of Procaspase3 to Caspase3 by Caspase9 in cytosol http://purl.obolibrary.org/obo/IEV_0000992 Hydrolysis of Caspase3/6/7 by Caspase9 in cytosol http://purl.obolibrary.org/obo/IEV_0000993 Hydrolysis of Procaspase7 to Caspase7 by Caspase9 in cytosol http://purl.obolibrary.org/obo/IEV_0000992 Hydrolysis of Caspase3/6/7 by Caspase9 in cytosol http://purl.obolibrary.org/obo/IEV_0003415 Hydrolysis of Procaspase3 by caspase8 in cytosol http://purl.obolibrary.org/obo/IEV_0001014 Hydrolysis of Procaspase3/6/7 by caspase8/10 in cytosol http://purl.obolibrary.org/obo/IEV_0001249 Cytosolic cation ion concentration decline (through cGMP activated cation ion channel) http://purl.obolibrary.org/obo/IEV_0001031 Cytosolic cation ion concentration decline http://purl.obolibrary.org/obo/IEV_0001045 Dissociation in inner space of mitochondria http://purl.obolibrary.org/obo/IEV_0001033 Dissociation in mitochondria http://purl.obolibrary.org/obo/IEV_0000950 Dissociation in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0001033 Dissociation in mitochondria http://purl.obolibrary.org/obo/IEV_0001047 Dissociation in nuclear membrane http://purl.obolibrary.org/obo/IEV_0001042 Dissociation in nucleus http://purl.obolibrary.org/obo/IEV_0001046 Dissociation in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001042 Dissociation in nucleus http://purl.obolibrary.org/obo/IEV_0001050 Dephosphorylation in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001049 Dephosphorylation in nucleus http://purl.obolibrary.org/obo/IEV_0001028 DNA fragmentation by CAD in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001051 Hydrolysis in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001027 DNA fragmentation by AIF in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001051 Hydrolysis in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000517 DNA fragmentation by EndoG in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001051 Hydrolysis in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000389 Phosphorylation of RB by Cdk4_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001074 Phosphorylation of RB by Cdk4/6 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001080 Gene expression of p21 by p53 http://purl.obolibrary.org/obo/IEV_0001110 Gene expression by p53 http://purl.obolibrary.org/obo/IEV_0001604 Gene expression of apoptotic factor by p53 http://purl.obolibrary.org/obo/IEV_0001110 Gene expression by p53 http://purl.obolibrary.org/obo/IEV_0001111 Gene expression of GADD45 by p53 http://purl.obolibrary.org/obo/IEV_0001110 Gene expression by p53 http://purl.obolibrary.org/obo/IEV_0001113 Gene expression of Mdm2 by p53 http://purl.obolibrary.org/obo/IEV_0001110 Gene expression by p53 http://purl.obolibrary.org/obo/IEV_0001112 Gene expression of 14-3-3 by p53 http://purl.obolibrary.org/obo/IEV_0001110 Gene expression by p53 http://purl.obolibrary.org/obo/IEV_0001158 Gene expression of p21 by Smad complex http://purl.obolibrary.org/obo/IEV_0001142 Gene expression by Smad complex http://purl.obolibrary.org/obo/IEV_0001143 Gene expression of p15 by Smad complex http://purl.obolibrary.org/obo/IEV_0001142 Gene expression by Smad complex http://purl.obolibrary.org/obo/IEV_0001162 Gene expression of p27 by Smad complex http://purl.obolibrary.org/obo/IEV_0001142 Gene expression by Smad complex http://purl.obolibrary.org/obo/IEV_0001155 Gene expression of p16 by Smad complex http://purl.obolibrary.org/obo/IEV_0001142 Gene expression by Smad complex http://purl.obolibrary.org/obo/IEV_0000886 Gene expression of I-Smad by R-Smad:Smad4 http://purl.obolibrary.org/obo/IEV_0001142 Gene expression by Smad complex http://purl.obolibrary.org/obo/IEV_0000155 Transcription by R-Smad:Smad4 in nucleus http://purl.obolibrary.org/obo/IEV_0001145 Transcription by Smad complex in nucleus http://purl.obolibrary.org/obo/IEV_0003866 Transcription of CKI by Smad complex in nucleus http://purl.obolibrary.org/obo/IEV_0001145 Transcription by Smad complex in nucleus http://purl.obolibrary.org/obo/IEV_0001191 Regulation of Jagged mediated Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0001178 Regulation of Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0001188 Regulation of Delta mediated Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0001178 Regulation of Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0001193 Positive regulation of Jagged mediated Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0001180 Positive regulation of Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0001192 Negative regulation of Jagged mediated Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0001179 Negative regulation of Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0001238 Translocation of sodium ion from extracellular to cytosol (through AMPA receptor) http://purl.obolibrary.org/obo/IEV_0001203 Translocation from extracellular to cytosol http://purl.obolibrary.org/obo/IEV_0001202 Translocation of Estrogen from extracellular to cytosol http://purl.obolibrary.org/obo/IEV_0001203 Translocation from extracellular to cytosol http://purl.obolibrary.org/obo/IEV_0001243 Translocation of calcium and sodium ion from extracellular to cytosol (through NMDA receptor) http://purl.obolibrary.org/obo/IEV_0001203 Translocation from extracellular to cytosol http://purl.obolibrary.org/obo/IEV_0001773 Translocation of Androgen from extracellular to cytosol http://purl.obolibrary.org/obo/IEV_0001203 Translocation from extracellular to cytosol http://purl.obolibrary.org/obo/IEV_0001212 Binding of Estrogen receptor and corepressor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001208 Binding of Estrogen receptor and transcription factor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001204 Binding of Estrogen receptor and SWI/SNF complex in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001208 Binding of Estrogen receptor and transcription factor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001209 Binding of Estrogen receptor and p160 coactivator in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001208 Binding of Estrogen receptor and transcription factor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001210 Binding of Estrogen receptor and cyclin D1 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001208 Binding of Estrogen receptor and transcription factor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001211 Binding of Estrogen receptor and MTA-1 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001208 Binding of Estrogen receptor and transcription factor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001220 Binding of Transcription factor complex and HAT in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001215 Transcription factor complex formation with Estrogen receptor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001208 Binding of Estrogen receptor and transcription factor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001215 Transcription factor complex formation with Estrogen receptor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001217 Binding of Transcription factor complex and HDAC in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001215 Transcription factor complex formation with Estrogen receptor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001636 Src activation signaling (through autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001606 Src family activation signaling (through autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001313 Src activation signaling (through Estrogen receptor) http://purl.obolibrary.org/obo/IEV_0001222 Src activation signaling http://purl.obolibrary.org/obo/IEV_0001225 Binding of Estrogen receptor alpha and MNAR http://purl.obolibrary.org/obo/IEV_0001224 Binding of Estrogen receptor and MNAR http://purl.obolibrary.org/obo/IEV_0001226 Binding of Estrogen receptor beta and MNAR http://purl.obolibrary.org/obo/IEV_0001224 Binding of Estrogen receptor and MNAR http://purl.obolibrary.org/obo/IEV_0001240 Depolarization state of the postsynaptic cell http://purl.obolibrary.org/obo/IEV_0001241 Changes in polarization state of postsynaptic cell membrane http://purl.obolibrary.org/obo/IEV_0001247 Cytosolic calcium ion concentration elevation (through Glutamate receptor) http://purl.obolibrary.org/obo/IEV_0001246 Cytosolic calcium ion concentration elevation http://purl.obolibrary.org/obo/IEV_0001250 Translocation of calcium ion from the cytosol to the extracellular http://purl.obolibrary.org/obo/IEV_0001251 Translocation from cytosol to extracellular http://purl.obolibrary.org/obo/IEV_0003736 Translocation of Argos from the cytosol to the extracellular http://purl.obolibrary.org/obo/IEV_0001251 Translocation from cytosol to extracellular http://purl.obolibrary.org/obo/IEV_0000262 Binding of TCR-CD3 complex and Fyn in cytosol http://purl.obolibrary.org/obo/IEV_0001252 Binding of TCR-CD3 complex and non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000260 Binding of TCR-CD3 complex and Lck in cytosol http://purl.obolibrary.org/obo/IEV_0001252 Binding of TCR-CD3 complex and non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000524 Binding of CD3 zeta and ZAP-70 in cytosol http://purl.obolibrary.org/obo/IEV_0001252 Binding of TCR-CD3 complex and non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0001276 Negative regulation of B cell receptor signaling (through CD72 and SHP-1) http://purl.obolibrary.org/obo/IEV_0001274 Negative regulation of B cell receptor signaling http://purl.obolibrary.org/obo/IEV_0002291 Negative regulation of B cell receptor signaling (through IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0002290 Regulation of B cell receptor signaling (through IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0001281 Phosphorylation of Ig alpha:beta by Syk in cytosol http://purl.obolibrary.org/obo/IEV_0001279 Phosphorylation of Ig alpha:beta by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0001282 Phosphorylation of Ig alpha:beta by Src family in cytosol http://purl.obolibrary.org/obo/IEV_0001279 Phosphorylation of Ig alpha:beta by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0002304 Phosphorylation of Ig alpha by Lyn in cytosol http://purl.obolibrary.org/obo/IEV_0001279 Phosphorylation of Ig alpha:beta by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0002305 Phosphorylation of Ig beta by Lyn in cytosol http://purl.obolibrary.org/obo/IEV_0001279 Phosphorylation of Ig alpha:beta by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0001293 Phosphorylation of Ig alpha:beta by Blk in cytosol http://purl.obolibrary.org/obo/IEV_0001282 Phosphorylation of Ig alpha:beta by Src family in cytosol http://purl.obolibrary.org/obo/IEV_0001292 Phosphorylation of Ig alpha:beta by Fyn in cytosol http://purl.obolibrary.org/obo/IEV_0001282 Phosphorylation of Ig alpha:beta by Src family in cytosol http://purl.obolibrary.org/obo/IEV_0001280 Phosphorylation of Ig alpha:beta by Lyn in cytosol http://purl.obolibrary.org/obo/IEV_0001282 Phosphorylation of Ig alpha:beta by Src family in cytosol http://purl.obolibrary.org/obo/IEV_0001300 Rac activation signaling http://purl.obolibrary.org/obo/IEV_0001301 Small GTPase activation signaling http://purl.obolibrary.org/obo/IEV_0001355 Activation of Raf1 by Ras-GTP along with PKC alpha in cytosol http://purl.obolibrary.org/obo/IEV_0001362 Activation of Raf by PKC in cytosol http://purl.obolibrary.org/obo/IEV_0002485 Activation of Raf-1 by PKC in cytosol http://purl.obolibrary.org/obo/IEV_0001362 Activation of Raf by PKC in cytosol http://purl.obolibrary.org/obo/IEV_0003838 Binding of Nck and PAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0001371 Binding of Nck and PAK in cytosol http://purl.obolibrary.org/obo/IEV_0001385 Recruitment of CARMA1 and BCL10 to the lipid raft of the synapse by PKC theta http://purl.obolibrary.org/obo/IEV_0001386 Recruitment to the raft http://purl.obolibrary.org/obo/IEV_0001096 Negative regulation of S phase http://purl.obolibrary.org/obo/IEV_0001083 Regulation of S phase http://purl.obolibrary.org/obo/IEV_0003861 Negative regulation of G1 phase http://purl.obolibrary.org/obo/IEV_0001404 Negative regulation of cell cycle process http://purl.obolibrary.org/obo/IEV_0001097 Positive regulation of S phase http://purl.obolibrary.org/obo/IEV_0001083 Regulation of S phase http://purl.obolibrary.org/obo/IEV_0000554 Regulation of PLC gamma signaling http://purl.obolibrary.org/obo/IEV_0001796 Regulation of CD4 T cell receptor signaling (through PLC gamma, calcineurin and NF-AT) http://purl.obolibrary.org/obo/IEV_0001409 Positive regulation of PLC signaling http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001408 Negative regulation of PLC signaling http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001862 Positive regulation of (phosphorylation of AKT(PKB) in AKT(PKB) activation signaling http://purl.obolibrary.org/obo/IEV_0001487 Positive regulation of AKT(PKB) activation signaling http://purl.obolibrary.org/obo/IEV_0001468 Selenoamino acid metabolism http://purl.obolibrary.org/obo/IEV_0001557 Amino acid derivative metabolism http://purl.obolibrary.org/obo/IEV_0001500 Biosynthesis of 12-, 14- and 16-membered macrolides http://purl.obolibrary.org/obo/IEV_0001559 Polyketide biosynthesis http://purl.obolibrary.org/obo/IEV_0001502 Biosynthesis of type II polyketide backbone http://purl.obolibrary.org/obo/IEV_0001559 Polyketide biosynthesis http://purl.obolibrary.org/obo/IEV_0001503 Biosynthesis of type II polyketide products http://purl.obolibrary.org/obo/IEV_0001559 Polyketide biosynthesis http://purl.obolibrary.org/obo/IEV_0001504 Polyketide sugar unit biosynthesis http://purl.obolibrary.org/obo/IEV_0001559 Polyketide biosynthesis http://purl.obolibrary.org/obo/IEV_0001499 Biosynthesis of vancomycin group antibiotics http://purl.obolibrary.org/obo/IEV_0001559 Polyketide biosynthesis http://purl.obolibrary.org/obo/IEV_0001506 Biosynthesis of siderophore group nonribosomal peptides http://purl.obolibrary.org/obo/IEV_0001559 Polyketide biosynthesis http://purl.obolibrary.org/obo/IEV_0001609 Fyn activation signaling http://purl.obolibrary.org/obo/IEV_0001589 Src family activation signaling http://purl.obolibrary.org/obo/IEV_0001222 Src activation signaling http://purl.obolibrary.org/obo/IEV_0001589 Src family activation signaling http://purl.obolibrary.org/obo/IEV_0001606 Src family activation signaling (through autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001589 Src family activation signaling http://purl.obolibrary.org/obo/IEV_0001610 Lck activation signaling http://purl.obolibrary.org/obo/IEV_0001589 Src family activation signaling http://purl.obolibrary.org/obo/IEV_0002303 Lyn activation signaling http://purl.obolibrary.org/obo/IEV_0001589 Src family activation signaling http://purl.obolibrary.org/obo/IEV_0001635 Lck inactivation signaling http://purl.obolibrary.org/obo/IEV_0001617 Negative regulation of Lck activation signaling http://purl.obolibrary.org/obo/IEV_0001634 Fyn inactivation signaling http://purl.obolibrary.org/obo/IEV_0001590 Src family inactivation signaling http://purl.obolibrary.org/obo/IEV_0001642 Src inactivation signaling http://purl.obolibrary.org/obo/IEV_0001590 Src family inactivation signaling http://purl.obolibrary.org/obo/IEV_0001895 Phosphorylation of Lck by Csk and inactive conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001597 Phosphorylation of Src family by Csk and inactive conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001645 Phosphorylation of Src by Csk and inactive conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001644 Phosphorylation of Src by non-receptor kinase and inactive conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001887 Phosphorylation of Fyn by Csk and inactive conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001596 Phosphorylation of Fyn by non-receptor kinase and inactive conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001115 Gene expression of BAX by p53 http://purl.obolibrary.org/obo/IEV_0001604 Gene expression of apoptotic factor by p53 http://purl.obolibrary.org/obo/IEV_0001650 Gene expression of BAK by p53 http://purl.obolibrary.org/obo/IEV_0001604 Gene expression of apoptotic factor by p53 http://purl.obolibrary.org/obo/IEV_0001651 Gene expression of Bid by p53 http://purl.obolibrary.org/obo/IEV_0001604 Gene expression of apoptotic factor by p53 http://purl.obolibrary.org/obo/IEV_0001653 Gene expression of PUMA by p53 http://purl.obolibrary.org/obo/IEV_0001604 Gene expression of apoptotic factor by p53 http://purl.obolibrary.org/obo/IEV_0001652 Gene expression of NOXA by p53 http://purl.obolibrary.org/obo/IEV_0001604 Gene expression of apoptotic factor by p53 http://purl.obolibrary.org/obo/IEV_0000519 Lck activation signaling (through autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001610 Lck activation signaling http://purl.obolibrary.org/obo/IEV_0000510 Autophosphorylation of Lck and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001607 Autophosphorylation of Src family and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0000536 Autophosphorylation of Fyn and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001607 Autophosphorylation of Src family and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001638 Dephosphorylation of Src_p by PTP and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001608 Dephosphorylation of Src family_p by PTP and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001598 Dephosphorylation of Fyn_p by PTP and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001608 Dephosphorylation of Src family_p by PTP and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001599 Dephosphorylation of Lck_p by PTP and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001608 Dephosphorylation of Src family_p by PTP and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001643 Dephosphorylation of Src_p by PTP in cytosol http://purl.obolibrary.org/obo/IEV_0001892 Src inactivation signaling (through PTP) http://purl.obolibrary.org/obo/IEV_0001594 Dephosphorylation of Fyn_p by PTP in cytosol http://purl.obolibrary.org/obo/IEV_0001611 Dephosphorylation of Src family_p by PTP in cytosol http://purl.obolibrary.org/obo/IEV_0001592 Dephosphorylation of Lck_p by PTP in cytosol http://purl.obolibrary.org/obo/IEV_0001611 Dephosphorylation of Src family_p by PTP in cytosol http://purl.obolibrary.org/obo/IEV_0001591 Phosphorylation of Lck by non-receptor kinase and inactive conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001612 Phosphorylation of Src family by non-receptor kinase and inactive conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001597 Phosphorylation of Src family by Csk and inactive conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001612 Phosphorylation of Src family by non-receptor kinase and inactive conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001644 Phosphorylation of Src by non-receptor kinase and inactive conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001612 Phosphorylation of Src family by non-receptor kinase and inactive conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001596 Phosphorylation of Fyn by non-receptor kinase and inactive conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001612 Phosphorylation of Src family by non-receptor kinase and inactive conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0001614 Negative regulation of Fyn activation signaling http://purl.obolibrary.org/obo/IEV_0000559 Negative regulation of Src family activation signaling http://purl.obolibrary.org/obo/IEV_0001615 Positive regulation of Fyn activation signaling http://purl.obolibrary.org/obo/IEV_0000560 Positive regulation of Src family activation signaling http://purl.obolibrary.org/obo/IEV_0001628 Regulation of Fyn activation signaling (through autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001613 Regulation of Fyn activation signaling http://purl.obolibrary.org/obo/IEV_0001629 Negative regulation of Fyn activation signaling (through autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001628 Regulation of Fyn activation signaling (through autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001630 Positive regulation of Fyn activation signaling (autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001628 Regulation of Fyn activation signaling (through autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001618 Positive regulation of Lck activation signaling http://purl.obolibrary.org/obo/IEV_0000560 Positive regulation of Src family activation signaling http://purl.obolibrary.org/obo/IEV_0001631 Regulation of Lck activation signaling (autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001616 Regulation of Lck activation signaling http://purl.obolibrary.org/obo/IEV_0001617 Negative regulation of Lck activation signaling http://purl.obolibrary.org/obo/IEV_0000559 Negative regulation of Src family activation signaling http://purl.obolibrary.org/obo/IEV_0001633 Positive regulation of Lck activation signaling (autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001631 Regulation of Lck activation signaling (autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001620 Negative regulation of Src activation signaling http://purl.obolibrary.org/obo/IEV_0001619 Regulation of Src activation signaling http://purl.obolibrary.org/obo/IEV_0001625 Regulation of src activation signaling (through Estrogen receptor) http://purl.obolibrary.org/obo/IEV_0001619 Regulation of Src activation signaling http://purl.obolibrary.org/obo/IEV_0001639 Regulation of Src activation signaling (through autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001619 Regulation of Src activation signaling http://purl.obolibrary.org/obo/IEV_0001621 Positive regulation of Src activation signaling http://purl.obolibrary.org/obo/IEV_0001619 Regulation of Src activation signaling http://purl.obolibrary.org/obo/IEV_0001626 Negative regulation of src activation signaling (through Estrogen receptor) http://purl.obolibrary.org/obo/IEV_0001625 Regulation of src activation signaling (through Estrogen receptor) http://purl.obolibrary.org/obo/IEV_0001640 Negative regulation of Src activation signaling (through autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001639 Regulation of Src activation signaling (through autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0000513 Lck inactivation signaling (through PTP) http://purl.obolibrary.org/obo/IEV_0002255 Negative regulation of (Lck activation signaling) http://purl.obolibrary.org/obo/IEV_0001623 Negative regulation of Src family activation signaling (autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0000559 Negative regulation of Src family activation signaling http://purl.obolibrary.org/obo/IEV_0001624 Positive regulation of Src family activation signaling (autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0000560 Positive regulation of Src family activation signaling http://purl.obolibrary.org/obo/IEV_0001627 Positive regulation of src activation signaling (through Estrogen receptor) http://purl.obolibrary.org/obo/IEV_0001621 Positive regulation of Src activation signaling http://purl.obolibrary.org/obo/IEV_0001889 Negative regulation of (dephosphorylation of Fyn) in Fyn activation signaling http://purl.obolibrary.org/obo/IEV_0001629 Negative regulation of Fyn activation signaling (through autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001888 Negative regulation of (Autophosphorylation of Fyn) in Fyn activation signaling http://purl.obolibrary.org/obo/IEV_0001629 Negative regulation of Fyn activation signaling (through autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001896 Negative regulation of Lck activation signaling (autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001631 Regulation of Lck activation signaling (autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001890 Lck inactivation signaling (through Csk) http://purl.obolibrary.org/obo/IEV_0001632 Negative regulation of (dephosphorylation of Lck) Lck activation signaling (autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001641 Positive regulation of Src activation signaling (through autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0001621 Positive regulation of Src activation signaling http://purl.obolibrary.org/obo/IEV_0001660 Translation of NOXA in cytosol http://purl.obolibrary.org/obo/IEV_0001662 Translation of apoptotic factor in cytosol http://purl.obolibrary.org/obo/IEV_0001663 Translation of BAK in cytosol http://purl.obolibrary.org/obo/IEV_0001662 Translation of apoptotic factor in cytosol http://purl.obolibrary.org/obo/IEV_0001664 Translation of Bid in cytosol http://purl.obolibrary.org/obo/IEV_0001662 Translation of apoptotic factor in cytosol http://purl.obolibrary.org/obo/IEV_0001665 Translation of PUMA in cytosol http://purl.obolibrary.org/obo/IEV_0001662 Translation of apoptotic factor in cytosol http://purl.obolibrary.org/obo/IEV_0001130 Translation of BAX in cytosol http://purl.obolibrary.org/obo/IEV_0001662 Translation of apoptotic factor in cytosol http://purl.obolibrary.org/obo/IEV_0001811 Negative feedback regulation of Wnt signaling pathway http://purl.obolibrary.org/obo/IEV_0001676 Negative regulation of Wnt signaling pathway http://purl.obolibrary.org/obo/IEV_0003562 Regulation of IGF1 signaling pathway http://purl.obolibrary.org/obo/IEV_0001687 Regulation of IGF signaling pathway http://purl.obolibrary.org/obo/IEV_0003560 Negative regulation of IGF1 signaling pathway http://purl.obolibrary.org/obo/IEV_0003562 Regulation of IGF1 signaling pathway http://purl.obolibrary.org/obo/IEV_0003563 Positive regulation of IGF1 signaling pathway http://purl.obolibrary.org/obo/IEV_0003562 Regulation of IGF1 signaling pathway http://purl.obolibrary.org/obo/IEV_0001696 Negative regulation of endothelin receptor signaling http://purl.obolibrary.org/obo/IEV_0000669 Negative regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0001697 Positive regulation of endothelin receptor signaling http://purl.obolibrary.org/obo/IEV_0000670 Positive regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0001875 Negative regulation of transcription in endothelin signaling by histone acetylation http://purl.obolibrary.org/obo/IEV_0001696 Negative regulation of endothelin receptor signaling http://purl.obolibrary.org/obo/IEV_0001723 Dephosphorylation of HDAC7 by protein phosphatase in cytosol http://purl.obolibrary.org/obo/IEV_0001701 Dephosphorylation of HDAC5/7 by protein phosphatase in cytosol http://purl.obolibrary.org/obo/IEV_0001724 Dephosphorylation of HDAC5 by protein phosphatase in cytosol http://purl.obolibrary.org/obo/IEV_0001701 Dephosphorylation of HDAC5/7 by protein phosphatase in cytosol http://purl.obolibrary.org/obo/IEV_0001716 Nuclear export of 14-3-3:HDAC5:Crm1 http://purl.obolibrary.org/obo/IEV_0001702 Nuclear export of 14-3-3:HDAC5/7:Crm1 http://purl.obolibrary.org/obo/IEV_0001717 Nuclear export of 14-3-3:HDAC7:Crm1 http://purl.obolibrary.org/obo/IEV_0001702 Nuclear export of 14-3-3:HDAC5/7:Crm1 http://purl.obolibrary.org/obo/IEV_0001721 Dissociation of 14-3-3 and HDAC5 in cytosol http://purl.obolibrary.org/obo/IEV_0001704 Dissociation of 14-3-3 and HDAC5/7 in cytosol http://purl.obolibrary.org/obo/IEV_0001722 Dissociation of 14-3-3 and HDAC7 in cytosol http://purl.obolibrary.org/obo/IEV_0001704 Dissociation of 14-3-3 and HDAC5/7 in cytosol http://purl.obolibrary.org/obo/IEV_0001882 Nuclear import of HDAC5 http://purl.obolibrary.org/obo/IEV_0001705 Nuclear import of HDAC5/7 http://purl.obolibrary.org/obo/IEV_0001883 Nuclear import of HDAC7 http://purl.obolibrary.org/obo/IEV_0001705 Nuclear import of HDAC5/7 http://purl.obolibrary.org/obo/IEV_0001714 Complex formation of 14-3-3:HDAC5:Crm1 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001706 Complex formation of 14-3-3:HDAC5/7:Crm1 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001715 Complex formation of 14-3-3:HDAC7:Crm1 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001706 Complex formation of 14-3-3:HDAC5/7:Crm1 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001706 Complex formation of 14-3-3:HDAC5/7:Crm1 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001711 Binding of transcription factor and Crm1 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001712 Binding of Stat1 and Crm1 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001711 Binding of transcription factor and Crm1 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001713 Binding of NFAT and Crm1 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001711 Binding of transcription factor and Crm1 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003729 Binding of Tel-1 and Crm1 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001711 Binding of transcription factor and Crm1 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000456 Binding of TRAF2 and ASK1 in cytosol http://purl.obolibrary.org/obo/IEV_0001725 Binding of TRAF2 and MAPKKK in cytosol http://purl.obolibrary.org/obo/IEV_0001726 Binding of TRAF2 and NIK in cytosol http://purl.obolibrary.org/obo/IEV_0001725 Binding of TRAF2 and MAPKKK in cytosol http://purl.obolibrary.org/obo/IEV_0000022 Dephosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001729 Dephosphorylation in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0001049 Dephosphorylation in nucleus http://purl.obolibrary.org/obo/IEV_0001729 Dephosphorylation in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0003454 Binding of GHR_p and SOCS-3 in cytosol http://purl.obolibrary.org/obo/IEV_0002221 Binding of SOCS3 and cytokine receptor in cytosol http://purl.obolibrary.org/obo/IEV_0003453 Binding of JAK2_p and SOCS-1 in cytosol http://purl.obolibrary.org/obo/IEV_0002231 Binding of SOCS1 and JAK in cytosol http://purl.obolibrary.org/obo/IEV_0003452 Binding of GHR_p and SOCS-2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001780 Regulation of Androgen receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001776 Regulation of Steroid receptor signaling http://purl.obolibrary.org/obo/IEV_0001777 Negative regulation of Steroid receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001778 Positive regulation of Steroid receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001786 Negative regulation of Androgen receptor signaling pathway by PIAS-mediated repression of Androgen receptor http://purl.obolibrary.org/obo/IEV_0001781 Negative regulation of Androgen receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001792 Negative regulation of calcineurin activation signaling http://purl.obolibrary.org/obo/IEV_0001797 Negative regulation of CD4 T cell receptor signaling (through PLC gamma, calcineurin and NF-AT) http://purl.obolibrary.org/obo/IEV_0001793 Positive regulation of calcineurin activation signaling http://purl.obolibrary.org/obo/IEV_0001798 Positive regulation of CD4 T cell receptor signaling (through PLC gamma, calcineurin and NF-AT) http://purl.obolibrary.org/obo/IEV_0001791 Regulation of calcineurin activation signaling http://purl.obolibrary.org/obo/IEV_0001796 Regulation of CD4 T cell receptor signaling (through PLC gamma, calcineurin and NF-AT) http://purl.obolibrary.org/obo/IEV_0001797 Negative regulation of CD4 T cell receptor signaling (through PLC gamma, calcineurin and NF-AT) http://purl.obolibrary.org/obo/IEV_0001375 Negative regulation of T cell receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001798 Positive regulation of CD4 T cell receptor signaling (through PLC gamma, calcineurin and NF-AT) http://purl.obolibrary.org/obo/IEV_0001376 Positive regulation of T cell receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001801 Positive regulation of Bad activation signaling http://purl.obolibrary.org/obo/IEV_0001799 Regulation of Bad activation signaling http://purl.obolibrary.org/obo/IEV_0001800 Negative regulation of Bad activation signaling http://purl.obolibrary.org/obo/IEV_0001799 Regulation of Bad activation signaling http://purl.obolibrary.org/obo/IEV_0001813 Negative feedback regulation of Wnt signaling pathway (through beta-TrCP) http://purl.obolibrary.org/obo/IEV_0001811 Negative feedback regulation of Wnt signaling pathway http://purl.obolibrary.org/obo/IEV_0000042 Binding of Wnt and Frizzled in extracellular http://purl.obolibrary.org/obo/IEV_0001816 Binding of Wnt and Wnt receptor in extracellular http://purl.obolibrary.org/obo/IEV_0001815 Binding of Wnt and LRP5/6 in extracellular http://purl.obolibrary.org/obo/IEV_0001816 Binding of Wnt and Wnt receptor in extracellular http://purl.obolibrary.org/obo/IEV_0001949 Binding of Wnt, Frizzled and Arrow/LRP5/6 in extracellular http://purl.obolibrary.org/obo/IEV_0001816 Binding of Wnt and Wnt receptor in extracellular http://purl.obolibrary.org/obo/IEV_0001961 Binding of Dkk, Arrow/LRP5/6 and Kremen in extracellular http://purl.obolibrary.org/obo/IEV_0001818 Binding of Dkk and Wnt receptor in extracellular http://purl.obolibrary.org/obo/IEV_0001765 Sumoylation of STAT1 by PIAS in nucleus http://purl.obolibrary.org/obo/IEV_0001825 Sumoylation of STAT1/3/4 by PIAS in nucleus http://purl.obolibrary.org/obo/IEV_0001826 Sumoylation of STAT1/3/4 by PIAS1/3 in nucleus http://purl.obolibrary.org/obo/IEV_0001825 Sumoylation of STAT1/3/4 by PIAS in nucleus http://purl.obolibrary.org/obo/IEV_0001827 Sumoylation of STAT1/3/4 by PIAS2/4 in nucleus http://purl.obolibrary.org/obo/IEV_0001825 Sumoylation of STAT1/3/4 by PIAS in nucleus http://purl.obolibrary.org/obo/IEV_0001825 Sumoylation of STAT1/3/4 by PIAS in nucleus http://purl.obolibrary.org/obo/IEV_0001831 Sumoylation of trans-activator by PIAS in nucleus http://purl.obolibrary.org/obo/IEV_0003690 Binding of trans-activator and PIAS in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001832 Binding of trans-activator and co-repressor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000148 Negative regulation of transcription by PIAS http://purl.obolibrary.org/obo/IEV_0001838 Negative regulation of transcription http://purl.obolibrary.org/obo/IEV_0003655 Negative regulation of transcription by AKT http://purl.obolibrary.org/obo/IEV_0001838 Negative regulation of transcription http://purl.obolibrary.org/obo/IEV_0003693 Negative regulation of transcription by BCL-6 http://purl.obolibrary.org/obo/IEV_0001838 Negative regulation of transcription http://purl.obolibrary.org/obo/IEV_0003709 Negative regulation of transcription by Tel-1 http://purl.obolibrary.org/obo/IEV_0001838 Negative regulation of transcription http://purl.obolibrary.org/obo/IEV_0001861 Negative regulation of (dephosphorylation of AKT(PKB) in negative regulation of AKT(PKB) activation signaling) http://purl.obolibrary.org/obo/IEV_0001860 Negative regulation of (negative regulation of AKT(PKB) activation signaling) http://purl.obolibrary.org/obo/IEV_0001864 HDAC nuclear import/export signaling http://purl.obolibrary.org/obo/IEV_0001863 Protein nuclear import/export signaling http://purl.obolibrary.org/obo/IEV_0001884 Dissociation of HDAC7 and MEF2 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001873 Dissociation of HDAC5/7 and MEF2 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001885 Dissociation of HDAC5 and MEF2 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001873 Dissociation of HDAC5/7 and MEF2 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001865 HDAC nuclear import signaling http://purl.obolibrary.org/obo/IEV_0001875 Negative regulation of transcription in endothelin signaling by histone acetylation http://purl.obolibrary.org/obo/IEV_0001891 Fyn inactivation signaling (through Csk) http://purl.obolibrary.org/obo/IEV_0001634 Fyn inactivation signaling http://purl.obolibrary.org/obo/IEV_0001899 Binding of phosphatidylserine and PKC theta and active conformational change of PKC theta in plasma membrane http://purl.obolibrary.org/obo/IEV_0001897 Binding of phosphatidylserine and PKC and active conformational change of PKC in plasma membrane http://purl.obolibrary.org/obo/IEV_0001898 Binding of phosphatidylserine and cPKC and active conformational change of cPKC in plasma membrane http://purl.obolibrary.org/obo/IEV_0001897 Binding of phosphatidylserine and PKC and active conformational change of PKC in plasma membrane http://purl.obolibrary.org/obo/IEV_0001901 Negative regulation of cPKC activation signaling http://purl.obolibrary.org/obo/IEV_0001911 Negative regulation of PKC activation signaling http://purl.obolibrary.org/obo/IEV_0001902 Positive regulation of cPKC activation signaling http://purl.obolibrary.org/obo/IEV_0001910 Positive regulation of PKC activation signaling http://purl.obolibrary.org/obo/IEV_0001905 Negative regulation of (binding of phosphatidylserine and cPKC) in cPKC activation signaling http://purl.obolibrary.org/obo/IEV_0001901 Negative regulation of cPKC activation signaling http://purl.obolibrary.org/obo/IEV_0001903 Negative regulation of (binding of calcium ion and cPKC) in cPKC activation signaling http://purl.obolibrary.org/obo/IEV_0001901 Negative regulation of cPKC activation signaling http://purl.obolibrary.org/obo/IEV_0001904 Negative regulation of (binding of DAG and cPKC) in cPKC activation signaling http://purl.obolibrary.org/obo/IEV_0001901 Negative regulation of cPKC activation signaling http://purl.obolibrary.org/obo/IEV_0001900 Regulation of cPKC activation signaling http://purl.obolibrary.org/obo/IEV_0001909 Regulation of PKC activation signaling http://purl.obolibrary.org/obo/IEV_0001910 Positive regulation of PKC activation signaling http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001911 Negative regulation of PKC activation signaling http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001912 Regulation of PKC theta activation signaling http://purl.obolibrary.org/obo/IEV_0001909 Regulation of PKC activation signaling http://purl.obolibrary.org/obo/IEV_0001914 Positive regulation of PKC theta activation signaling http://purl.obolibrary.org/obo/IEV_0001912 Regulation of PKC theta activation signaling http://purl.obolibrary.org/obo/IEV_0001913 Negative regulation of PKC theta activation signaling http://purl.obolibrary.org/obo/IEV_0001912 Regulation of PKC theta activation signaling http://purl.obolibrary.org/obo/IEV_0001919 Negative regulation of (binding of calcium ion and PKC) in PKC activation signaling http://purl.obolibrary.org/obo/IEV_0001911 Negative regulation of PKC activation signaling http://purl.obolibrary.org/obo/IEV_0001920 Negative regulation of (binding of DAG and PKC) in PKC activation signaling http://purl.obolibrary.org/obo/IEV_0001911 Negative regulation of PKC activation signaling http://purl.obolibrary.org/obo/IEV_0001921 Negative regulation of (binding of phosphatidylserine and PKC) in PKC activation signaling http://purl.obolibrary.org/obo/IEV_0001911 Negative regulation of PKC activation signaling http://purl.obolibrary.org/obo/IEV_0001915 Negative regulation of (binding of DAG and PKC theta) in PKC theta activation signaling http://purl.obolibrary.org/obo/IEV_0001913 Negative regulation of PKC theta activation signaling http://purl.obolibrary.org/obo/IEV_0001916 Negative regulation of (binding of phosphatidylserine and PKC theta) in PKC theta activation signaling http://purl.obolibrary.org/obo/IEV_0001913 Negative regulation of PKC theta activation signaling http://purl.obolibrary.org/obo/IEV_0001908 Dissociation of phosphatidylserine and cPKC in plasma membrane http://purl.obolibrary.org/obo/IEV_0001924 Dissociation of phosphatidylserine and PKC in plasma membrane http://purl.obolibrary.org/obo/IEV_0001918 Dissociation of phosphatidylserine and PKC theta in plasma membrane http://purl.obolibrary.org/obo/IEV_0001924 Dissociation of phosphatidylserine and PKC in plasma membrane http://purl.obolibrary.org/obo/IEV_0001926 Negative regulation of PKA activation signaling http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001927 Positive regulation of PKA activation signaling http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001929 Binding of Mdm2 and p14ARF in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001934 Binding of Mdm2 and ARF in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000870 Binding of Mdm2 and p19ARF in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001934 Binding of Mdm2 and ARF in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001938 Translocation of Wnt from ER to extracellular space http://purl.obolibrary.org/obo/IEV_0001939 Translocation from ER to extracellular space http://purl.obolibrary.org/obo/IEV_0001944 Translocation of LRP6 from ER to plasma membrane http://purl.obolibrary.org/obo/IEV_0001940 Translocation of Arrow/LRP5/6 from ER to plasma membrane http://purl.obolibrary.org/obo/IEV_0001940 Translocation of Arrow/LRP5/6 from ER to plasma membrane http://purl.obolibrary.org/obo/IEV_0001941 Translocation from ER to plasma membrane http://purl.obolibrary.org/obo/IEV_0002580 Translocation of hedgehog from ER to plasma membrane http://purl.obolibrary.org/obo/IEV_0001941 Translocation from ER to plasma membrane http://purl.obolibrary.org/obo/IEV_0003885 Translocation of BMP from ER to plasma membrane http://purl.obolibrary.org/obo/IEV_0001941 Translocation from ER to plasma membrane http://purl.obolibrary.org/obo/IEV_0001946 Translocation of Arrow/LRP5/6 from cytosol to plasma membrane http://purl.obolibrary.org/obo/IEV_0001942 Translocation from cytosol to plasma membrane http://purl.obolibrary.org/obo/IEV_0003451 Translocation of GLUT4 from cytosol to plasma membrane http://purl.obolibrary.org/obo/IEV_0001942 Translocation from cytosol to plasma membrane http://purl.obolibrary.org/obo/IEV_0003732 Translocation of Kek from cytosol to plasma membrane http://purl.obolibrary.org/obo/IEV_0001942 Translocation from cytosol to plasma membrane http://purl.obolibrary.org/obo/IEV_0003789 Translocation of FGF receptor from cytosol to plasma membrane http://purl.obolibrary.org/obo/IEV_0001942 Translocation from cytosol to plasma membrane http://purl.obolibrary.org/obo/IEV_0000740 Cation ion transport from extracellular to cytosol through cation channel http://purl.obolibrary.org/obo/IEV_0000733 Negative regulation of heterotrimeric GPCR signaling pathway (through photon, rhodopsin, G alpha t and PDE) http://purl.obolibrary.org/obo/IEV_0000274 Calcium ion transport from ER to cytosol through calcium ion channel http://purl.obolibrary.org/obo/IEV_0000739 Ion transport through ion channel http://purl.obolibrary.org/obo/IEV_0001945 Translocation of Arrow/LRP5/6 from ER to cytosol http://purl.obolibrary.org/obo/IEV_0001943 Translocation from ER to cytosol http://purl.obolibrary.org/obo/IEV_0001948 Translocation of LRP6 from ER to cytosol http://purl.obolibrary.org/obo/IEV_0001945 Translocation of Arrow/LRP5/6 from ER to cytosol http://purl.obolibrary.org/obo/IEV_0001947 Translocation of LRP6 from cytosol to plasma membrane http://purl.obolibrary.org/obo/IEV_0001946 Translocation of Arrow/LRP5/6 from cytosol to plasma membrane http://purl.obolibrary.org/obo/IEV_0001963 Binding of Dkk2, Arrow/LRP5/6 and Kremen2 in extracellular http://purl.obolibrary.org/obo/IEV_0001961 Binding of Dkk, Arrow/LRP5/6 and Kremen in extracellular http://purl.obolibrary.org/obo/IEV_0001962 Binding of Dkk1, LRP6 and Kremen2 in extracellular http://purl.obolibrary.org/obo/IEV_0001961 Binding of Dkk, Arrow/LRP5/6 and Kremen in extracellular http://purl.obolibrary.org/obo/IEV_0001966 Internalization of LRP6 http://purl.obolibrary.org/obo/IEV_0001965 Internalization of Arrow/LRP5/6 http://purl.obolibrary.org/obo/IEV_0001742 Phosphorylation of beta-catenin by GSK3beta in cytosol http://purl.obolibrary.org/obo/IEV_0001970 Phosphorylation of beta-catenin by GSK-3 in cytosol http://purl.obolibrary.org/obo/IEV_0003557 Binding of IRS-1_p and PI3K in cytosol http://purl.obolibrary.org/obo/IEV_0001977 Binding of IRS and PI3K in cytosol http://purl.obolibrary.org/obo/IEV_0001982 Binding of G alpha s-GDP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0001981 Binding of G alpha-GDP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0002019 Binding of G alpha i-GDP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0001981 Binding of G alpha-GDP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0002032 Binding of G alpha q-GDP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0001981 Binding of G alpha-GDP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000766 Binding of G alpha t-GDP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0001981 Binding of G alpha-GDP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0002064 Binding of GPCR and G alpha q in cytosol http://purl.obolibrary.org/obo/IEV_0001983 Binding of GPCR and G alpha in cytosol http://purl.obolibrary.org/obo/IEV_0001984 Binding of GPCR and G alpha s in cytosol http://purl.obolibrary.org/obo/IEV_0001983 Binding of GPCR and G alpha in cytosol http://purl.obolibrary.org/obo/IEV_0002018 Binding of GPCR and G alpha i in cytosol http://purl.obolibrary.org/obo/IEV_0001983 Binding of GPCR and G alpha in cytosol http://purl.obolibrary.org/obo/IEV_0002065 Binding of GPCR and G alpha t in cytosol http://purl.obolibrary.org/obo/IEV_0001983 Binding of GPCR and G alpha in cytosol http://purl.obolibrary.org/obo/IEV_0002417 Binding of D1-like receptor and G alpha s in cytosol http://purl.obolibrary.org/obo/IEV_0001984 Binding of GPCR and G alpha s in cytosol http://purl.obolibrary.org/obo/IEV_0003431 Binding of Adenosine A2A receptor and G alpha s in cytosol http://purl.obolibrary.org/obo/IEV_0001984 Binding of GPCR and G alpha s in cytosol http://purl.obolibrary.org/obo/IEV_0001989 Epac activation signaling http://purl.obolibrary.org/obo/IEV_0001988 cAMP mediated signaling http://purl.obolibrary.org/obo/IEV_0001990 Cyclic nucleotide-gated cannel activation signaling http://purl.obolibrary.org/obo/IEV_0001988 cAMP mediated signaling http://purl.obolibrary.org/obo/IEV_0000686 Binding of G alpha s-GTP and adenylate cyclase in cytosol http://purl.obolibrary.org/obo/IEV_0001992 Binding of G alpha s-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0001993 Binding of G alpha s-GTP and Src family in cytosol http://purl.obolibrary.org/obo/IEV_0001992 Binding of G alpha s-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0000699 Binding of G alpha s-GTP and RGS in cytosol http://purl.obolibrary.org/obo/IEV_0000674 Binding of G alpha-GTP and RGS in cytosol http://purl.obolibrary.org/obo/IEV_0000689 Binding of G alpha i-GTP and adenylate cyclase in cytosol http://purl.obolibrary.org/obo/IEV_0001997 Binding of G alpha i-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0000697 Binding of G alpha i-GTP and RGS in cytosol http://purl.obolibrary.org/obo/IEV_0000674 Binding of G alpha-GTP and RGS in cytosol http://purl.obolibrary.org/obo/IEV_0002076 Binding of G alpha i-GTP and Rap1GAP2 in cytosol http://purl.obolibrary.org/obo/IEV_0001997 Binding of G alpha i-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0000778 Binding of G alpha o-GTP and PLC beta in cytosol http://purl.obolibrary.org/obo/IEV_0001998 Binding of G alpha o-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0002006 Negative regulation of heterotrimeric GPCR signaling pathway (through G alpha s, cholera toxin, adenylate cyclase and cAMP) http://purl.obolibrary.org/obo/IEV_0000669 Negative regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0002007 Positive regulation of heterotrimeric GPCR signaling pathway (through G alpha s, cholera toxin, adenylate cyclase and cAMP) http://purl.obolibrary.org/obo/IEV_0000670 Positive regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0002009 Negative regulation of G alpha s-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0002010 Positive regulation of G alpha s-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0002066 Negative regulation of (Hydrolysis of GTP by G alpha s-GTP and RGS) (through Adenylate cyclase activation signaling) http://purl.obolibrary.org/obo/IEV_0002009 Negative regulation of G alpha s-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002011 Negative regulation of (Hydrolysis of GTP by G alpha s-GTP and RGS) (through G alpha s GDP-GTP exchange signaling) http://purl.obolibrary.org/obo/IEV_0002009 Negative regulation of G alpha s-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0000736 Binding of G alpha t-GTP and RGS in cytosol http://purl.obolibrary.org/obo/IEV_0000674 Binding of G alpha-GTP and RGS in cytosol http://purl.obolibrary.org/obo/IEV_0000728 Binding of G alpha t-GTP and cGMP PDE in cytosol http://purl.obolibrary.org/obo/IEV_0002013 Binding of G alpha t-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0002000 Binding of G alpha 11-GTP and PLC beta in cytosol http://purl.obolibrary.org/obo/IEV_0002014 Binding of G alpha 11-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0002023 Positive regulation of G alpha i-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002024 Regulation of G alpha i-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002033 Negative regulation of G alpha i-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002024 Regulation of G alpha i-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0000694 Negative regulation of (G alpha i GDP-GTP exchange signaling) http://purl.obolibrary.org/obo/IEV_0002026 Negative regulation of heteromeric GPCR signaling pathway (through G alpha i) http://purl.obolibrary.org/obo/IEV_0002020 Negative regulation of (Binding of G alpha i-GTP and adenylate cyclase) http://purl.obolibrary.org/obo/IEV_0002026 Negative regulation of heteromeric GPCR signaling pathway (through G alpha i) http://purl.obolibrary.org/obo/IEV_0002030 Negative regulation of (Binding of GPCR ligand and GPCR) http://purl.obolibrary.org/obo/IEV_0002026 Negative regulation of heteromeric GPCR signaling pathway (through G alpha i) http://purl.obolibrary.org/obo/IEV_0002034 Negative regulation of (Hydrolysis of GTP by G alpha i-GTP and RGS) http://purl.obolibrary.org/obo/IEV_0002033 Negative regulation of G alpha i-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002036 Negative regulation of G alpha q-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002035 Regulation of G alpha q-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002038 Positive regulation of G alpha q-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002035 Regulation of G alpha q-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002037 Negative regulation of (Hydrolysis of GTP by G alpha q-GTP and RGS) http://purl.obolibrary.org/obo/IEV_0002036 Negative regulation of G alpha q-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002040 Positive regulation of G alpha t-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002039 Regulation of G alpha t-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002041 Negative regulation of G alpha t-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002039 Regulation of G alpha t-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002042 Negative regulation of (Hydrolysis of GTP by G alpha t-GTP and RGS) http://purl.obolibrary.org/obo/IEV_0002041 Negative regulation of G alpha t-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002045 Regulation of G alpha s GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002044 Regulation of G alpha GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002046 Negative regulation of G alpha GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0002047 Positive regulation of G alpha GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0002048 Regulation of G alpha i GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002044 Regulation of G alpha GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002049 Regulation of G alpha q GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002044 Regulation of G alpha GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002050 Regulation of G alpha t GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002044 Regulation of G alpha GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002053 Negative regulation of G alpha s GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002046 Negative regulation of G alpha GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002057 Positive regulation of G alpha s GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002047 Positive regulation of G alpha GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002051 Negative regulation of G alpha i GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002048 Regulation of G alpha i GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002052 Negative regulation of G alpha q GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002049 Regulation of G alpha q GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002054 Negative regulation of G alpha t GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002050 Regulation of G alpha t GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002059 Negative regulation of (GDP-GTP exchange of G alpha) http://purl.obolibrary.org/obo/IEV_0002046 Negative regulation of G alpha GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002055 Positive regulation of G alpha i GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002048 Regulation of G alpha i GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002056 Positive regulation of G alpha q GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002049 Regulation of G alpha q GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002058 Positive regulation of G alpha t GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002050 Regulation of G alpha t GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002060 Negative regulation of (GDP-GTP exchange of G alpha i) http://purl.obolibrary.org/obo/IEV_0002051 Negative regulation of G alpha i GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002061 Negative regulation of (GDP-GTP exchange of G alpha q) http://purl.obolibrary.org/obo/IEV_0002052 Negative regulation of G alpha q GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002062 Negative regulation of (GDP-GTP exchange of G alpha s) http://purl.obolibrary.org/obo/IEV_0002053 Negative regulation of G alpha s GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002063 Negative regulation of (GDP-GTP exchange of G alpha t) http://purl.obolibrary.org/obo/IEV_0002054 Negative regulation of G alpha t GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002084 B-Raf activation signaling http://purl.obolibrary.org/obo/IEV_0002072 Raf activation signaling http://purl.obolibrary.org/obo/IEV_0002199 Raf activation signaling (through RasGRP) http://purl.obolibrary.org/obo/IEV_0002072 Raf activation signaling http://purl.obolibrary.org/obo/IEV_0001364 Raf activation signaling (through PKC) http://purl.obolibrary.org/obo/IEV_0002072 Raf activation signaling http://purl.obolibrary.org/obo/IEV_0000602 Raf activation signaling (through Grb2 and Sos) http://purl.obolibrary.org/obo/IEV_0001258 Ras mediated signaling http://purl.obolibrary.org/obo/IEV_0001981 Binding of G alpha-GDP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0002074 Binding of G alpha-GDP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0002075 Binding of G alpha o -GDP and Rap1GAP1 in cytosol http://purl.obolibrary.org/obo/IEV_0002074 Binding of G alpha-GDP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0002080 Rap1 activation signaling (through cAMP and Epac) http://purl.obolibrary.org/obo/IEV_0002079 Rap1 activation signaling http://purl.obolibrary.org/obo/IEV_0002081 Rap1 activation signaling (through cAMP, PKA, Cbl and C3G) http://purl.obolibrary.org/obo/IEV_0002079 Rap1 activation signaling http://purl.obolibrary.org/obo/IEV_0000228 Phosphorylation of JNK by MKK4/7_p in cytosol http://purl.obolibrary.org/obo/IEV_0002095 Phosphorylation of JNK by MKK_p in cytosol http://purl.obolibrary.org/obo/IEV_0002208 Transcription of IL2 by AP-1 in nucleus http://purl.obolibrary.org/obo/IEV_0002099 Transcription of cytokine by AP-1 in nucleus http://purl.obolibrary.org/obo/IEV_0002133 Binding of GAF and GAS element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002100 Binding of STAT dimer and GAS in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002137 Binding of STAT5 homodimer and GAS element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002100 Binding of STAT dimer and GAS in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002139 Binding of STAT4 homodimer and GAS element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002100 Binding of STAT dimer and GAS in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002134 Binding of STAT3 homodimer and GAS element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002100 Binding of STAT dimer and GAS in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002101 Gene expression of SOCS by STAT dimer http://purl.obolibrary.org/obo/IEV_0002102 Gene expression by STAT dimer http://purl.obolibrary.org/obo/IEV_0003686 Gene expression of vvl by STAT dimer http://purl.obolibrary.org/obo/IEV_0002102 Gene expression by STAT dimer http://purl.obolibrary.org/obo/IEV_0002225 Transcription of SOCS3 by STAT dimer in nucleus http://purl.obolibrary.org/obo/IEV_0002103 Transcription of SOCS by STAT dimer in nucleus http://purl.obolibrary.org/obo/IEV_0002240 Transcription of SOCS1 by STAT dimer in nucleus http://purl.obolibrary.org/obo/IEV_0002103 Transcription of SOCS by STAT dimer in nucleus http://purl.obolibrary.org/obo/IEV_0002227 Translation of SOCS3 in cytosol http://purl.obolibrary.org/obo/IEV_0002104 Translation of SOCS in cytosol http://purl.obolibrary.org/obo/IEV_0002241 Translation of SOCS1 in cytosol http://purl.obolibrary.org/obo/IEV_0002104 Translation of SOCS in cytosol http://purl.obolibrary.org/obo/IEV_0000235 Phosphorylation of p38 by MKK3/6_p in cytosol http://purl.obolibrary.org/obo/IEV_0002106 Phosphorylation of p38 by MKK_p in cytosol http://purl.obolibrary.org/obo/IEV_0001856 Binding of BMP2 and BMP receptor I in extracellular http://purl.obolibrary.org/obo/IEV_0002172 Binding of BMP2 and BMP receptor I/II in extracellular http://purl.obolibrary.org/obo/IEV_0003570 Binding of BMP2 and BMP receptor II in extracellular http://purl.obolibrary.org/obo/IEV_0003571 Binding of BMP and BMP receptor II in extracellular http://purl.obolibrary.org/obo/IEV_0001847 Positive regulation of (transcription by R-Smad:Smad4 ) in TGF beta super family signaling pathway by (Smad4 sumoylation by PIAS1) http://purl.obolibrary.org/obo/IEV_0002190 Positive regulation of (transcription by R-Smad:Smad4 ) in TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0002201 Positive regulation of CD4 T cell receptor signaling (through Ras Vav, Rac and JNK cascade) http://purl.obolibrary.org/obo/IEV_0001376 Positive regulation of T cell receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0002198 Negative regulation of CD4 T cell receptor signaling (through Ras Vav, Rac and JNK cascade) http://purl.obolibrary.org/obo/IEV_0001375 Negative regulation of T cell receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0002434 Phosphorylation of JNK1 by MKK4_p in cytosol http://purl.obolibrary.org/obo/IEV_0002204 Phosphorylation of JNK by MKK4(SEK1)_p in cytosol http://purl.obolibrary.org/obo/IEV_0002207 Nuclear export of mRNA (IL2) http://purl.obolibrary.org/obo/IEV_0002210 Nuclear export of mRNA (cytokine) http://purl.obolibrary.org/obo/IEV_0002209 Translation of IL2 in cytosol http://purl.obolibrary.org/obo/IEV_0002211 Translation of cytokine in cytosol http://purl.obolibrary.org/obo/IEV_0002719 Phosphorylation of STAT3 dimer by serine kinase in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0002247 Phosphorylation of STAT dimer by serine kinase in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0002250 Positive regulation of CD4 T cell receptor signaling (through Ras and Erk cascade) http://purl.obolibrary.org/obo/IEV_0001376 Positive regulation of T cell receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0002249 Negative regulation of CD4 T cell receptor signaling (through Ras and Erk cascade) http://purl.obolibrary.org/obo/IEV_0001375 Negative regulation of T cell receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0002276 Transcription of Siamois gene in nucleus http://purl.obolibrary.org/obo/IEV_0002282 Transcription by beta-catenin:TCF complex in nucleus http://purl.obolibrary.org/obo/IEV_0002547 Transcription of Ubx gene in nucleus http://purl.obolibrary.org/obo/IEV_0002282 Transcription by beta-catenin:TCF complex in nucleus http://purl.obolibrary.org/obo/IEV_0002548 Transcription of Engrailed gene in nucleus http://purl.obolibrary.org/obo/IEV_0002282 Transcription by beta-catenin:TCF complex in nucleus http://purl.obolibrary.org/obo/IEV_0002550 Transcription of end-1 gene in nucleus http://purl.obolibrary.org/obo/IEV_0002282 Transcription by beta-catenin:TCF complex in nucleus http://purl.obolibrary.org/obo/IEV_0002275 Transcription of Xtwn gene in nucleus http://purl.obolibrary.org/obo/IEV_0002284 Transcription by beta-catenin:TCF complex and Smad4 in nucleus http://purl.obolibrary.org/obo/IEV_0002292 Positive regulation of B cell receptor signaling (through IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0001275 Positive regulation of B cell receptor signaling http://purl.obolibrary.org/obo/IEV_0002318 Activation of IKK complex by PKC beta in cytosol http://purl.obolibrary.org/obo/IEV_0002317 Activation of IKK complex by PKCs in cytosol http://purl.obolibrary.org/obo/IEV_0000750 Binding of G alpha q-GTP and PLC beta in cytosol http://purl.obolibrary.org/obo/IEV_0002403 Binding of G alpha q-GTP and PLC in cytosol http://purl.obolibrary.org/obo/IEV_0000623 Phosphorylation of AKT by IlK in cytosol http://purl.obolibrary.org/obo/IEV_0002415 Phosphorylation of Akt by protein kinase in cytosol http://purl.obolibrary.org/obo/IEV_0003656 Phosphorylation of AKT by TOR of TORC2 in cytosol http://purl.obolibrary.org/obo/IEV_0002415 Phosphorylation of Akt by protein kinase in cytosol http://purl.obolibrary.org/obo/IEV_0003330 Binding of FGF8 and FGFR1 in extracellular http://purl.obolibrary.org/obo/IEV_0002486 Binding of FGF and FGFR in extracellular http://purl.obolibrary.org/obo/IEV_0003331 FGF8:FGFR1 dimerization in plasma membrane http://purl.obolibrary.org/obo/IEV_0002487 Dimerization of FGFR in plasma membrane http://purl.obolibrary.org/obo/IEV_0003332 Autophosphorylation of FGFR1 in plasma membrane http://purl.obolibrary.org/obo/IEV_0002488 Autophosphorylation of FGFR in plasma membrane http://purl.obolibrary.org/obo/IEV_0003334 Phosphorylation of FRS2 by FGFR1_p in cytosol http://purl.obolibrary.org/obo/IEV_0002491 Phosphorylation of FRS2 by FGFR_p in cytosol http://purl.obolibrary.org/obo/IEV_0002516 Negative regulation of (Activation of PSH by GNBP3) http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0002523 Clustering of integrins in plasma membrane http://purl.obolibrary.org/obo/IEV_0002525 Clustering in plasma membrane http://purl.obolibrary.org/obo/IEV_0002526 Complex formation of integrin complex, caveolin-1, Fyn and Shc http://purl.obolibrary.org/obo/IEV_0002529 Complex formation of integrin complex, caveolin, Fyn and Shc http://purl.obolibrary.org/obo/IEV_0003839 GDP-GTP exchange of Cdc42 by RhoGEF6 in cytosol http://purl.obolibrary.org/obo/IEV_0002531 GDP-GTP exchange of Cdc42 by RhoGEF in cytosol http://purl.obolibrary.org/obo/IEV_0002544 Stabilization and accumulation of cytoplasmic beta-catenin in cytosol http://purl.obolibrary.org/obo/IEV_0002546 Accumulation in cytosol http://purl.obolibrary.org/obo/IEV_0002553 Activation of APR-1 in cytosol http://purl.obolibrary.org/obo/IEV_0002554 Activation of APC in cytosol http://purl.obolibrary.org/obo/IEV_0002556 Activation of SGG-1 in cytosol http://purl.obolibrary.org/obo/IEV_0002555 Activation of GSK3beta in cytosol http://purl.obolibrary.org/obo/IEV_0001182 Binding of Notch1 and Jagged1 in extracellular http://purl.obolibrary.org/obo/IEV_0002558 Binding of Notch and Serrate/Jagged in extracellular http://purl.obolibrary.org/obo/IEV_0002619 Binding of Notch and Serrate in extracellular http://purl.obolibrary.org/obo/IEV_0002558 Binding of Notch and Serrate/Jagged in extracellular http://purl.obolibrary.org/obo/IEV_0002869 IMP + Pyrophosphate = Hypoxanthine + 5-Phospho-alpha-D-ribose 1-diphosphate( EC:2.4.2.8 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0002967 Thymidine + Orthophosphate = 2-Deoxy-D-ribose 1-phosphate + Thymine( EC:2.4.2.4 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0003016 Nicotinamide D-ribonucleotide + Pyrophosphate = Nicotinamide + 5-Phospho-alpha-D-ribose 1-diphosphate( EC:2.4.2.12 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0003024 Deoxy-guanosine + Orthophosphate = 2-Deoxy-D-ribose 1-phosphate + Guanine( EC:2.4.2.4 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0002561 Glycosylation in cytosol http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0002742 purine nucleoside + Orthophosphate = purine + D-ribose 1-phosphate( EC:2.4.2.1 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0002772 Deoxy-uridine + Orthophosphate = 2-Deoxy-D-ribose 1-phosphate + Uracil( EC:2.4.2.4 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0002791 Orotidine 5'-phosphate + Pyrophosphate = Orotic acid + 5-Phospho-alpha-D-ribose 1-diphosphate( EC:2.4.2.10 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0002864 AMP + Pyrophosphate = Adenine + 5-Phospho-alpha-D-ribose 1-diphosphate( EC:2.4.2.7 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0002880 XMP + Pyrophosphate = Xanthine + 5-Phospho-alpha-D-ribose 1-diphosphate( EC:2.4.2.8 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0002888 GMP + Pyrophosphate = Guanine + 5-Phospho-alpha-D-ribose 1-diphosphate( EC:2.4.2.7 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0002941 Deoxy-inosine + Orthophosphate = 2-Deoxy-D-ribose 1-phosphate + Hypoxanthine( EC:2.4.2.4 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0003018 Deoxy-adenosine + Orthophosphate = 2-Deoxy-D-ribose 1-phosphate + Adenine( EC:2.4.2.1 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0003059 Uridine + Orthophosphate = Uracil + D-Ribose 1-phosphate( EC:2.4.2.3 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0003075 L-Glutamine + 5-Phospho-alpha-D-ribose 1-diphosphate + H2O => L-Glutamic acid + 5-Phospho-ribosyl-1-amine + Pyrophosphate( EC:2.4.2.14 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0003323 AMP + Pyrophosphate = Adenine + 5-Phospho-alpha-D-ribose 1-diphosphate( EC:2.4.2.8 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0003165 UDP-D-galactose + D-Glucose => UDP + Lactose( EC:2.4.1.22 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0002973 5-Phospho-alpha-D-ribose 1-diphosphate + 2,3-Pyridine-dicarboxylic acid => Nicotinate D-ribonucleotide + Pyrophosphate + CO2( EC:2.4.2.19 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0003324 GMP + Pyrophosphate = Guanine + 5-Phospho-alpha-D-ribose 1-diphosphate( EC:2.4.2.8 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0002828 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + Pyrophosphate = 5-Amino-4-imidazole-carboxyamide + 5-Phospho-alpha-D-ribose 1-diphosphate( EC:2.4.2.7 ) http://purl.obolibrary.org/obo/IEV_0002560 Glycosylation http://purl.obolibrary.org/obo/IEV_0002559 Glycosylation of Notch by Fringe in cytosol http://purl.obolibrary.org/obo/IEV_0002561 Glycosylation in cytosol http://purl.obolibrary.org/obo/IEV_0002585 Glycosylation of HSPG by Exostosin in cytosol http://purl.obolibrary.org/obo/IEV_0002561 Glycosylation in cytosol http://purl.obolibrary.org/obo/IEV_0002565 Phosphorylation of Notch (NIC) in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002566 Ubiquitination of Notch (NIC) by SCF ubiquitin ligase complex including sel-10 in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0002567 Proteasome degradation of Notch (NIC) by 26S proteasome in cytosol http://purl.obolibrary.org/obo/IEV_0000021 Proteasome degradation in cytosol http://purl.obolibrary.org/obo/IEV_0002575 Autocleavage in ER http://purl.obolibrary.org/obo/IEV_0002572 Autocleavage http://purl.obolibrary.org/obo/IEV_0002584 Translocation of Dlp/Dally from Golgi to plasma membrane http://purl.obolibrary.org/obo/IEV_0002583 Translocation of HSPG from Golgi to plasma membrane http://purl.obolibrary.org/obo/IEV_0002606 Transcription of ptc gene in nucleus http://purl.obolibrary.org/obo/IEV_0002605 Transcription of Hh target gene in nucleus http://purl.obolibrary.org/obo/IEV_0002607 Transcription of dpp gene in nucleus http://purl.obolibrary.org/obo/IEV_0002605 Transcription of Hh target gene in nucleus http://purl.obolibrary.org/obo/IEV_0003776 Transcription of Gli1 gene in nucleus http://purl.obolibrary.org/obo/IEV_0002605 Transcription of Hh target gene in nucleus http://purl.obolibrary.org/obo/IEV_0002616 Translocation of LRP6 from ER to Golgi http://purl.obolibrary.org/obo/IEV_0002615 Translocation of Arrow/LRP5/6 from ER to Golgi http://purl.obolibrary.org/obo/IEV_0002618 Translocation of LRP6 from Golgi to plasma membrane http://purl.obolibrary.org/obo/IEV_0002617 Translocation of Arrow/LRP5/6 from Golgi to plasma membrane http://purl.obolibrary.org/obo/IEV_0003405 FGFR1 signaling pathway http://purl.obolibrary.org/obo/IEV_0002626 FGF receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0002444 Phosphorylation of Shc by EGFR_p in cytosol http://purl.obolibrary.org/obo/IEV_0002631 Phosphorylation of Shc by RTK in cytosol http://purl.obolibrary.org/obo/IEV_0002451 Phosphorylation of Shc by PDGF Receptor_p in cytosol http://purl.obolibrary.org/obo/IEV_0002631 Phosphorylation of Shc by RTK in cytosol http://purl.obolibrary.org/obo/IEV_0002469 Phosphorylation of Shc by Met_p in cytosol http://purl.obolibrary.org/obo/IEV_0002631 Phosphorylation of Shc by RTK in cytosol http://purl.obolibrary.org/obo/IEV_0002474 Phosphorylation of Shc by TRK_p in cytosol http://purl.obolibrary.org/obo/IEV_0002631 Phosphorylation of Shc by RTK in cytosol http://purl.obolibrary.org/obo/IEV_0000492 Phosphorylation of Shc by insulin receptor in cytosol http://purl.obolibrary.org/obo/IEV_0002631 Phosphorylation of Shc by RTK in cytosol http://purl.obolibrary.org/obo/IEV_0003554 Phosphorylation of Shc by IGF receptor_p in cytosol http://purl.obolibrary.org/obo/IEV_0002631 Phosphorylation of Shc by RTK in cytosol http://purl.obolibrary.org/obo/IEV_0000773 Heterotrimeric GPCR signaling pathway (through melatonin, G alpha o and PLCbeta) http://purl.obolibrary.org/obo/IEV_0002635 Heterotrimeric GPCR signaling pathway (through G alpha o) http://purl.obolibrary.org/obo/IEV_0003467 Cleavage and activation of Relish by caspase8 in cytosol http://purl.obolibrary.org/obo/IEV_0003859 Activation of NF-kappaB in cytosol http://purl.obolibrary.org/obo/IEV_0003502 Cleavage of Spaetzle by serine protease in extracellular http://purl.obolibrary.org/obo/IEV_0003409 Cleavage in extracellular http://purl.obolibrary.org/obo/IEV_0003565 Cleavage of IGFBP-3 by PSA in extracellular http://purl.obolibrary.org/obo/IEV_0003409 Cleavage in extracellular http://purl.obolibrary.org/obo/IEV_0003713 Cleavage of TGF alpha by Rhomboid in Golgi http://purl.obolibrary.org/obo/IEV_0003714 Cleavage in Golgi http://purl.obolibrary.org/obo/IEV_0003270 10-Formyl-tetrahydro-folic acid + 5'-Phospho-ribosyl-glycinamide => Tetrahydrofolate + 5'-Phospho-ribosyl-N-formyl-glycinamide( EC:2.1.2.2 ) http://purl.obolibrary.org/obo/IEV_0002674 Formylation http://purl.obolibrary.org/obo/IEV_0002798 10-Formyl-tetrahydro-folic acid + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide => Tetrahydrofolate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide( EC:2.1.2.3 ) http://purl.obolibrary.org/obo/IEV_0002674 Formylation http://purl.obolibrary.org/obo/IEV_0002573 Cholesterol modification http://purl.obolibrary.org/obo/IEV_0002681 lipid addition http://purl.obolibrary.org/obo/IEV_0002819 L-Glutamate 5-semialdehyde => (S)-1-Pyrroline-5-carboxylic acid + H2O( nonenzymatic ) http://purl.obolibrary.org/obo/IEV_0002720 nonenzymatic reaction http://purl.obolibrary.org/obo/IEV_0002905 2-Amino-3-carboxy-muconate semialdehyde => 2,3-Pyridine-dicarboxylic acid + H2O( nonenzymatic ) http://purl.obolibrary.org/obo/IEV_0002720 nonenzymatic reaction http://purl.obolibrary.org/obo/IEV_0003274 L-2-Amino-3-oxo-butanoic acid => Amino-acetone + CO2( nonenzymatic ) http://purl.obolibrary.org/obo/IEV_0002720 nonenzymatic reaction http://purl.obolibrary.org/obo/IEV_0003233 NADPH + Prostaglandin E2 + H+ => NADP+ + Prostaglandin F2alpha( EC:1.1.1.184 ) http://purl.obolibrary.org/obo/IEV_0002723 Secondary alcohol + NADP+ = Ketone + NADPH + H+( EC:1.1.1.184 ) http://purl.obolibrary.org/obo/IEV_0003060 NADP+ + D-Sorbitol = NADPH + alpha-D-Glucose + H+( EC:1.1.1.21 ) http://purl.obolibrary.org/obo/IEV_0002724 Alditol + NADP+ = Aldose + NADPH + H+( EC:1.1.1.21 ) http://purl.obolibrary.org/obo/IEV_0003006 L-Proline + 2-Oxo-glutaric acid + O2 => trans-4-Hydroxy-L-proline + Succinic acid + CO2( EC:1.14.11.2 ) http://purl.obolibrary.org/obo/IEV_0002726 procollagen L-proline + 2-Oxo-glutaric acid + O2 = procollagen trans-4-hydroxy-L-proline + Succinic acid + CO2( EC:1.14.11.2 ) http://purl.obolibrary.org/obo/IEV_0003251 Glycine + H2O + O2 => Glyoxylic acid + NH3 + H2O2( EC:1.4.3.3 ) http://purl.obolibrary.org/obo/IEV_0002733 D-amino acid + H2O + O2 = 2-oxo acid + NH3 + H2O2( EC:1.4.3.3 ) http://purl.obolibrary.org/obo/IEV_0003076 L-Noradrenaline + H2O + O2 => 3,4-Dihydroxy-mandelaldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0002734 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0002790 Phenyl-ethylamine + H2O + O2 => Phenyl-acetaldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0002734 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0002952 L-Normetanephrine + H2O + O2 => 3-Methoxy-4-hydroxy-phenyl-glycolaldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0002734 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0003124 N-Acetyl-putrescine + H2O + O2 => N4-Acetylaminobutanal + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0002734 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0003159 Tryptamine + H2O + O2 => Indole-3-acetaldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0002734 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0003226 N-Methyl-histamine + H2O + O2 => Methylimidazole acetaldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0002734 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0003253 Serotonin + H2O + O2 => 5-Hydroxy-indole-acetaldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0002734 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0003276 Amino-acetone + H2O + O2 => Methyl-glyoxal + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0002734 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0003282 3-Methoxy-tyramine + H2O + O2 => 3-methoxy-4-hydroxy-phenyl-acetaldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0002734 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0002899 Tyramine + H2O + O2 => 4-Hydroxy-phenyl-acetaldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0002734 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0003147 Dopamine + H2O + O2 => 3,4-Dihydroxy-phenyl-acetaldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0002734 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.4 ) http://purl.obolibrary.org/obo/IEV_0003071 Amino-acetone + O2 + H2O => Methyl-glyoxal + H2O2 + NH3( EC:1.4.3.21 ) http://purl.obolibrary.org/obo/IEV_0002735 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.21 ) http://purl.obolibrary.org/obo/IEV_0003133 Tryptamine + O2 + H2O => Indole-3-acetaldehyde + H2O2 + NH3( EC:1.4.3.22 ) http://purl.obolibrary.org/obo/IEV_0002735 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.21 ) http://purl.obolibrary.org/obo/IEV_0003138 Tyramine + O2 + H2O => 4-Hydroxy-phenyl-acetaldehyde + H2O2 + NH3( EC:1.4.3.21 ) http://purl.obolibrary.org/obo/IEV_0002735 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.21 ) http://purl.obolibrary.org/obo/IEV_0003173 Putrescine + O2 + H2O => 4-Amino-butyraldehyde + H2O2 + NH3( EC:1.4.3.22 ) http://purl.obolibrary.org/obo/IEV_0002735 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.21 ) http://purl.obolibrary.org/obo/IEV_0003105 Histamine + O2 + H2O => Imidazole-4-acetaldehyde + NH3 + H2O2( EC:1.4.3.22 ) http://purl.obolibrary.org/obo/IEV_0002735 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.21 ) http://purl.obolibrary.org/obo/IEV_0003047 Phenyl-ethylamine + O2 + H2O => Phenyl-acetaldehyde + H2O2 + NH3( EC:1.4.3.21 ) http://purl.obolibrary.org/obo/IEV_0002735 Primary amine + H2O + O2 = Aldehyde + NH3 + H2O2( EC:1.4.3.21 ) http://purl.obolibrary.org/obo/IEV_0002799 NAD+ + Dihydro-lipoylprotein = NADH + Lipoylprotein + H+( EC:1.8.1.4 ) http://purl.obolibrary.org/obo/IEV_0002736 protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+( EC:1.8.1.4 ) http://purl.obolibrary.org/obo/IEV_0002838 NAD+ + Enzyme N6-(dihydrolipoyl)lysine = NADH + Enzyme N6-(lipoyl)lysine + H+( EC:1.8.1.4 ) http://purl.obolibrary.org/obo/IEV_0002736 protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+( EC:1.8.1.4 ) http://purl.obolibrary.org/obo/IEV_0003088 CoA + 2-Methyl-3-acetoacetyl-CoA => Acetyl-CoA + Propanoyl-CoA( EC:2.3.1.16 ) http://purl.obolibrary.org/obo/IEV_0002739 Acyl-CoA + Acetyl-CoA = CoA + 3-Oxoacyl-CoA( EC:2.3.1.16 ) http://purl.obolibrary.org/obo/IEV_0002860 N-Ribosyl-nicotinamide + Orthophosphate = Nicotinamide + D-Ribose 1-phosphate( EC:2.4.2.1 ) http://purl.obolibrary.org/obo/IEV_0002742 purine nucleoside + Orthophosphate = purine + D-ribose 1-phosphate( EC:2.4.2.1 ) http://purl.obolibrary.org/obo/IEV_0002988 Adenosine + Orthophosphate = Adenine + D-Ribose 1-phosphate( EC:2.4.2.1 ) http://purl.obolibrary.org/obo/IEV_0002742 purine nucleoside + Orthophosphate = purine + D-ribose 1-phosphate( EC:2.4.2.1 ) http://purl.obolibrary.org/obo/IEV_0003011 Inosine + Orthophosphate = Hypoxanthine + D-Ribose 1-phosphate( EC:2.4.2.1 ) http://purl.obolibrary.org/obo/IEV_0002742 purine nucleoside + Orthophosphate = purine + D-ribose 1-phosphate( EC:2.4.2.1 ) http://purl.obolibrary.org/obo/IEV_0003025 Xanthosine + Orthophosphate = Xanthine + D-Ribose 1-phosphate( EC:2.4.2.1 ) http://purl.obolibrary.org/obo/IEV_0002742 purine nucleoside + Orthophosphate = purine + D-ribose 1-phosphate( EC:2.4.2.1 ) http://purl.obolibrary.org/obo/IEV_0003131 Nicotinate D-ribonucleoside + Orthophosphate = Nicotinic acid + D-Ribose 1-phosphate( EC:2.4.2.1 ) http://purl.obolibrary.org/obo/IEV_0002742 purine nucleoside + Orthophosphate = purine + D-ribose 1-phosphate( EC:2.4.2.1 ) http://purl.obolibrary.org/obo/IEV_0003062 Guanosine + Orthophosphate = Guanine + D-Ribose 1-phosphate( EC:2.4.2.1 ) http://purl.obolibrary.org/obo/IEV_0002742 purine nucleoside + Orthophosphate = purine + D-ribose 1-phosphate( EC:2.4.2.1 ) http://purl.obolibrary.org/obo/IEV_0003275 N-Acetyl-D-mannosamine 6-phosphate + Phosphoenol-pyruvic acid + H2O => N-Acetyl-neuraminate 9-phosphate + Orthophosphate( EC:2.5.1.57 ) http://purl.obolibrary.org/obo/IEV_0002743 Phosphoenol-pyruvic acid + N-acyl-D-mannosamine 6-phosphate + H2O = N-acylneuraminate 9-phosphate + Orthophosphate( EC:2.5.1.57 ) http://purl.obolibrary.org/obo/IEV_0003028 ATP + D-Glucosamine => ADP + D-Glucosamine 6-phosphate( EC:2.7.1.1 ) http://purl.obolibrary.org/obo/IEV_0002744 ATP + D-hexose = ADP + D-hexose 6-phosphate( EC:2.7.1.1 ) http://purl.obolibrary.org/obo/IEV_0002829 ATP + D-Fructose => ADP + beta-D-Fructose 6-phosphate( EC:2.7.1.1 ) http://purl.obolibrary.org/obo/IEV_0002744 ATP + D-hexose = ADP + D-hexose 6-phosphate( EC:2.7.1.1 ) http://purl.obolibrary.org/obo/IEV_0003245 ATP + D-Mannose => ADP + D-Mannose 6-phosphate( EC:2.7.1.1 ) http://purl.obolibrary.org/obo/IEV_0002744 ATP + D-hexose = ADP + D-hexose 6-phosphate( EC:2.7.1.1 ) http://purl.obolibrary.org/obo/IEV_0003259 ATP + beta-D-Glucose => ADP + beta-D-Glucose 6-phosphate( EC:2.7.1.1 ) http://purl.obolibrary.org/obo/IEV_0002744 ATP + D-hexose = ADP + D-hexose 6-phosphate( EC:2.7.1.1 ) http://purl.obolibrary.org/obo/IEV_0002929 ATP + Deoxy-cytidine => ADP + dCMP( EC:2.7.1.74 ) http://purl.obolibrary.org/obo/IEV_0002746 Nucleoside triphosphate + deoxycytidine = Nucleoside diphosphate + dCMP( EC:2.7.1.74 ) http://purl.obolibrary.org/obo/IEV_0003132 CTP + N-Glycolyl-neuraminic acid => Pyrophosphate + CMP-N-glycolyl-neuraminic acid( EC:2.7.7.43 ) http://purl.obolibrary.org/obo/IEV_0002748 CTP + N-acylneuraminate = Pyrophosphate + CMP-N-acylneuraminate( EC:2.7.7.43 ) http://purl.obolibrary.org/obo/IEV_0003249 CTP + N-Acetyl-neuraminic acid => Pyrophosphate + CMP-N-acetyl-neuraminic acid( EC:2.7.7.43 ) http://purl.obolibrary.org/obo/IEV_0002748 CTP + N-acylneuraminate = Pyrophosphate + CMP-N-acylneuraminate( EC:2.7.7.43 ) http://purl.obolibrary.org/obo/IEV_0003070 3',5'-Cyclic GMP + H2O => GMP( EC:3.1.4.17 ) http://purl.obolibrary.org/obo/IEV_0002752 nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate( EC:3.1.4.17 ) http://purl.obolibrary.org/obo/IEV_0003005 3',5'-Cyclic AMP + H2O => AMP( EC:3.1.4.17 ) http://purl.obolibrary.org/obo/IEV_0002752 nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate( EC:3.1.4.17 ) http://purl.obolibrary.org/obo/IEV_0003201 N-Formyl-L-aspartic acid + H2O => L-Aspartic acid + Formic acid( EC:3.5.1.15 ) http://purl.obolibrary.org/obo/IEV_0002754 N-acyl-L-aspartate + H2O = Carboxylate + L-Aspartic acid( EC:3.5.1.15 ) http://purl.obolibrary.org/obo/IEV_0003104 N-Acetyl-L-aspartic acid + H2O => L-Aspartic acid + Acetic acid( EC:3.5.1.15 ) http://purl.obolibrary.org/obo/IEV_0002754 N-acyl-L-aspartate + H2O = Carboxylate + L-Aspartic acid( EC:3.5.1.15 ) http://purl.obolibrary.org/obo/IEV_0003084 NAD+ + H2O => Nicotinamide D-ribonucleotide + AMP( EC:3.6.1.9 ) http://purl.obolibrary.org/obo/IEV_0002758 dinucleotide + H2O = 2 mononucleotide( EC:3.6.1.9 ) http://purl.obolibrary.org/obo/IEV_0002776 ATP + dGDP = ADP + dGTP( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0002907 ATP + Nucleoside diphosphate = ADP + Nucleoside triphosphate( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0002786 ATP + UDP = ADP + UTP( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0002907 ATP + Nucleoside diphosphate = ADP + Nucleoside triphosphate( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0002978 ATP + dIDP = ADP + dITP( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0002907 ATP + Nucleoside diphosphate = ADP + Nucleoside triphosphate( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0002992 ATP + dTDP = ADP + dTTP( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0002907 ATP + Nucleoside diphosphate = ADP + Nucleoside triphosphate( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0003010 ATP + dCDP = ADP + dCTP( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0002907 ATP + Nucleoside diphosphate = ADP + Nucleoside triphosphate( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0003127 ATP + dADP = ADP + dATP( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0002907 ATP + Nucleoside diphosphate = ADP + Nucleoside triphosphate( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0003135 ATP + GDP = ADP + GTP( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0002907 ATP + Nucleoside diphosphate = ADP + Nucleoside triphosphate( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0003189 ATP + dUDP = ADP + dUTP( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0002907 ATP + Nucleoside diphosphate = ADP + Nucleoside triphosphate( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0002814 ATP + IDP = ADP + ITP( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0002907 ATP + Nucleoside diphosphate = ADP + Nucleoside triphosphate( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0003327 ATP + ADP = ADP + ATP( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0002907 ATP + Nucleoside diphosphate = ADP + Nucleoside triphosphate( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0002953 ATP + CDP = ADP + CTP( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0002907 ATP + Nucleoside diphosphate = ADP + Nucleoside triphosphate( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0002920 2-Oxo-glutaric acid + L-Ornithine = L-Glutamic acid + L-Glutamate 5-semialdehyde( EC:2.6.1.13 ) http://purl.obolibrary.org/obo/IEV_0002951 2-Oxo acid + L-Ornithine = L-Amino acid + L-Glutamate 5-semialdehyde( EC:2.6.1.13 ) http://purl.obolibrary.org/obo/IEV_0003083 Acetyl-CoA + Serotonin => CoA + N-Acetyl-serotonin( EC:2.3.1.87 ) http://purl.obolibrary.org/obo/IEV_0003315 Acetyl-CoA + 2-arylethylamine = CoA + N-acetyl-2-arylethylamine( EC:2.3.1.87 ) http://purl.obolibrary.org/obo/IEV_0003868 Binding of ETS1_p and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003336 Binding of ETS1/2_p and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003786 Transcription of SRF gene in nucleus http://purl.obolibrary.org/obo/IEV_0003337 Transcription of ETS target gene in nucleus http://purl.obolibrary.org/obo/IEV_0003348 Transcription of Sef gene in nucleus http://purl.obolibrary.org/obo/IEV_0003337 Transcription of ETS target gene in nucleus http://purl.obolibrary.org/obo/IEV_0003354 Transcription of Mkp3 gene in nucleus http://purl.obolibrary.org/obo/IEV_0003337 Transcription of ETS target gene in nucleus http://purl.obolibrary.org/obo/IEV_0003719 Transcription of Sprouty gene in nucleus http://purl.obolibrary.org/obo/IEV_0003337 Transcription of ETS target gene in nucleus http://purl.obolibrary.org/obo/IEV_0003782 Transcription of FGF receptor gene in nucleus http://purl.obolibrary.org/obo/IEV_0003337 Transcription of ETS target gene in nucleus http://purl.obolibrary.org/obo/IEV_0003726 Transcription of Kek gene in nucleus http://purl.obolibrary.org/obo/IEV_0003337 Transcription of ETS target gene in nucleus http://purl.obolibrary.org/obo/IEV_0003705 Transcription of Mae gene in nucleus http://purl.obolibrary.org/obo/IEV_0003337 Transcription of ETS target gene in nucleus http://purl.obolibrary.org/obo/IEV_0003722 Transcription of Argos gene in nucleus http://purl.obolibrary.org/obo/IEV_0003337 Transcription of ETS target gene in nucleus http://purl.obolibrary.org/obo/IEV_0002099 Transcription of cytokine by AP-1 in nucleus http://purl.obolibrary.org/obo/IEV_0003388 Transcription by AP-1 in nucleus http://purl.obolibrary.org/obo/IEV_0003587 Cleavage of BMP in extracellular http://purl.obolibrary.org/obo/IEV_0003409 Cleavage in extracellular http://purl.obolibrary.org/obo/IEV_0003889 Cleavage of Chordin by Tld in extracellular http://purl.obolibrary.org/obo/IEV_0003409 Cleavage in extracellular http://purl.obolibrary.org/obo/IEV_0003424 Binding of DAG and PKC delta and active conformational change of PKC delta in cytosol http://purl.obolibrary.org/obo/IEV_0003426 Binding of DAG and nPKC and active conformational change of nPKC in cytosol http://purl.obolibrary.org/obo/IEV_0001289 Binding of DAG and PKC theta and active conformational change of PKC theta in cytosol http://purl.obolibrary.org/obo/IEV_0003426 Binding of DAG and nPKC and active conformational change of nPKC in cytosol http://purl.obolibrary.org/obo/IEV_0003479 Transcription of drosomycin by Relish in nucleus http://purl.obolibrary.org/obo/IEV_0003478 Transcription of antimicrobial peptide by Relish in nucleus http://purl.obolibrary.org/obo/IEV_0003481 Transcription of defensin by DIF:Relish in nucleus http://purl.obolibrary.org/obo/IEV_0003478 Transcription of antimicrobial peptide by Relish in nucleus http://purl.obolibrary.org/obo/IEV_0003482 Transcription of drosocin by Relish in nucleus http://purl.obolibrary.org/obo/IEV_0003478 Transcription of antimicrobial peptide by Relish in nucleus http://purl.obolibrary.org/obo/IEV_0003483 Transcription of diptericin by Relish in nucleus http://purl.obolibrary.org/obo/IEV_0003478 Transcription of antimicrobial peptide by Relish in nucleus http://purl.obolibrary.org/obo/IEV_0003476 Transcription of attacin by Relish in nucleus http://purl.obolibrary.org/obo/IEV_0003478 Transcription of antimicrobial peptide by Relish in nucleus http://purl.obolibrary.org/obo/IEV_0003480 Transcription of cecropin by Relish in nucleus http://purl.obolibrary.org/obo/IEV_0003478 Transcription of antimicrobial peptide by Relish in nucleus http://purl.obolibrary.org/obo/IEV_0003505 Cleavage of Spaetzle by PSH in extracellular http://purl.obolibrary.org/obo/IEV_0003502 Cleavage of Spaetzle by serine protease in extracellular http://purl.obolibrary.org/obo/IEV_0003517 Transcription of antimicrobial peptide by DIF in nucleus http://purl.obolibrary.org/obo/IEV_0003518 Transcription of antimicrobial peptide in nucleus http://purl.obolibrary.org/obo/IEV_0003478 Transcription of antimicrobial peptide by Relish in nucleus http://purl.obolibrary.org/obo/IEV_0003518 Transcription of antimicrobial peptide in nucleus http://purl.obolibrary.org/obo/IEV_0003527 Transcription of antimicrobial peptide by DIF:Dorsal in nucleus http://purl.obolibrary.org/obo/IEV_0003518 Transcription of antimicrobial peptide in nucleus http://purl.obolibrary.org/obo/IEV_0003537 Transcription of antimicrobial peptide by Dorsal in nucleus http://purl.obolibrary.org/obo/IEV_0003518 Transcription of antimicrobial peptide in nucleus http://purl.obolibrary.org/obo/IEV_0003535 Expression of drosomycin by Dorsal http://purl.obolibrary.org/obo/IEV_0003533 Expression of antimicrobial peptide by Dorsal http://purl.obolibrary.org/obo/IEV_0003536 Transcription of drosomycin by Dorsal in nucleus http://purl.obolibrary.org/obo/IEV_0003537 Transcription of antimicrobial peptide by Dorsal in nucleus http://purl.obolibrary.org/obo/IEV_0003544 Negative regulation of Ras-Raf-MAPK signaling by spred http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0003545 Positive regulation of Ras-Raf-MAPK signaling by spred http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0002588 Inactivation of Smo by Ptc in plasma membrane http://purl.obolibrary.org/obo/IEV_0003548 Inactivation in plasma membrane http://purl.obolibrary.org/obo/IEV_0003566 Binding of IGF-1 and IGFBP-5 in extracellular http://purl.obolibrary.org/obo/IEV_0003561 Binding of IGF-1 and IGFBP in extracellular http://purl.obolibrary.org/obo/IEV_0003564 Binding of IGF-1 and IGFBP-3 in extracellular http://purl.obolibrary.org/obo/IEV_0003561 Binding of IGF-1 and IGFBP in extracellular http://purl.obolibrary.org/obo/IEV_0003572 Binding of BMP2:BMP receptor II and BMP receptor I in extracellular http://purl.obolibrary.org/obo/IEV_0003574 Binding of BMP:BMP receptor II and BMP receptor I in plasma membrane http://purl.obolibrary.org/obo/IEV_0003580 Dissociation of BMP receptor complex and Smad1 in cytosol http://purl.obolibrary.org/obo/IEV_0003582 Dissociation of BMP receptor complex and R-Smad in cytosol http://purl.obolibrary.org/obo/IEV_0000160 Phosphorylation of TGF-b receptor I by TGF beta receptor II in cytosol http://purl.obolibrary.org/obo/IEV_0003583 Phosphorylation of TGF beta superfamily receptor I by TGF beta superfamily receptor II in cytosol http://purl.obolibrary.org/obo/IEV_0002177 Phosphorylation of BMPR1 by BMPR2 in cytosol http://purl.obolibrary.org/obo/IEV_0003583 Phosphorylation of TGF beta superfamily receptor I by TGF beta superfamily receptor II in cytosol http://purl.obolibrary.org/obo/IEV_0000157 Phosphorylation of R-Smad by TGF beta receptor I in cytosol http://purl.obolibrary.org/obo/IEV_0003584 Phosphorylation of R-Smad by TGF beta superfamily receptor I in cytosol http://purl.obolibrary.org/obo/IEV_0003585 Phosphorylation of R-Smad by BMP receptor I in cytosol http://purl.obolibrary.org/obo/IEV_0003584 Phosphorylation of R-Smad by TGF beta superfamily receptor I in cytosol http://purl.obolibrary.org/obo/IEV_0000159 Complex formation of R-Smad and Smad4 in cytosol http://purl.obolibrary.org/obo/IEV_0003586 Complex formation of R-Smad and Co-Smad in cytosol http://purl.obolibrary.org/obo/IEV_0003582 Dissociation of BMP receptor complex and R-Smad in cytosol http://purl.obolibrary.org/obo/IEV_0003591 Dissociation of TGF beta superfamily receptor complex and R-Smad in cytosol http://purl.obolibrary.org/obo/IEV_0003581 Binding of BMP receptor complex and R-Smad in cytosol http://purl.obolibrary.org/obo/IEV_0003592 Binding of TGF beta superfamily receptor complex and R-Smad in cytosol http://purl.obolibrary.org/obo/IEV_0001855 Binding of TGF beta:TGF beta receptor II and TGF beta receptor I in plasma membrane http://purl.obolibrary.org/obo/IEV_0003593 Binding of TGF beta super family:Type II receptor and Type I receptor in plasma membrane http://purl.obolibrary.org/obo/IEV_0003574 Binding of BMP:BMP receptor II and BMP receptor I in plasma membrane http://purl.obolibrary.org/obo/IEV_0003593 Binding of TGF beta super family:Type II receptor and Type I receptor in plasma membrane http://purl.obolibrary.org/obo/IEV_0001854 Binding of TGF beta and TGF-beta receptor II in extracellular http://purl.obolibrary.org/obo/IEV_0003594 Binding of TGF beta superfamily and TGF beta superfamily receptor II in extracellular http://purl.obolibrary.org/obo/IEV_0003571 Binding of BMP and BMP receptor II in extracellular http://purl.obolibrary.org/obo/IEV_0003573 Binding of BMP and BMP receptor I/II in extracellular http://purl.obolibrary.org/obo/IEV_0003619 Binding of IRS-2 and IL-4 receptor in cytosol http://purl.obolibrary.org/obo/IEV_0003617 Binding of IRS and IL-4 receptor in cytosol http://purl.obolibrary.org/obo/IEV_0003618 Binding of IRS-1 and IL-4 receptor in cytosol http://purl.obolibrary.org/obo/IEV_0003617 Binding of IRS and IL-4 receptor in cytosol http://purl.obolibrary.org/obo/IEV_0003663 Gene expression of MAFbx by FOXO http://purl.obolibrary.org/obo/IEV_0003628 Gene expression by FOXO http://purl.obolibrary.org/obo/IEV_0003664 Gene expression of MuRF1 by FOXO http://purl.obolibrary.org/obo/IEV_0003628 Gene expression by FOXO http://purl.obolibrary.org/obo/IEV_0003673 Gene expression of 4EBP by FOXO http://purl.obolibrary.org/obo/IEV_0003628 Gene expression by FOXO http://purl.obolibrary.org/obo/IEV_0000067 Phosphorylation of S6K1 by TOR of TORC1 in cytosol http://purl.obolibrary.org/obo/IEV_0003638 Phosphorylation of p70S6K by TOR of TORC1 in cytosol http://purl.obolibrary.org/obo/IEV_0003640 Phosphorylation of S6RP by S6K1 in cytosol http://purl.obolibrary.org/obo/IEV_0003641 Phosphorylation of S6RP by p70S6K in cytosol http://purl.obolibrary.org/obo/IEV_0003674 Negative regulation of FOXO-mediated transcription by AKT http://purl.obolibrary.org/obo/IEV_0003655 Negative regulation of transcription by AKT http://purl.obolibrary.org/obo/IEV_0003642 Dissociation of 4EBP-1 and eIF4E in cytosol http://purl.obolibrary.org/obo/IEV_0003672 Dissociation of 4EBP and eIF4E in cytosol http://purl.obolibrary.org/obo/IEV_0003679 Negative regulation of AKT(PKB)-TOR signaling http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0003680 Positive regulation of AKT(PKB)-TOR signaling http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0003691 Binding of STAT and PIAS in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003690 Binding of trans-activator and PIAS in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003692 Binding of STAT and PIAS in cytosol http://purl.obolibrary.org/obo/IEV_0003696 Binding of trans-activator and PIAS in cytosol http://purl.obolibrary.org/obo/IEV_0003781 Gene expression of FGF receptor by ETS1 http://purl.obolibrary.org/obo/IEV_0003699 Gene expression by ETS1/2 http://purl.obolibrary.org/obo/IEV_0003347 Gene expression of Sef by ETS1/2 http://purl.obolibrary.org/obo/IEV_0003699 Gene expression by ETS1/2 http://purl.obolibrary.org/obo/IEV_0003353 Gene expression of Mkp3 by ETS1/2 http://purl.obolibrary.org/obo/IEV_0003699 Gene expression by ETS1/2 http://purl.obolibrary.org/obo/IEV_0003703 Gene expression of Mae by ETS1 http://purl.obolibrary.org/obo/IEV_0003699 Gene expression by ETS1/2 http://purl.obolibrary.org/obo/IEV_0003717 Gene expression of Sprouty by ETS1/2 http://purl.obolibrary.org/obo/IEV_0003699 Gene expression by ETS1/2 http://purl.obolibrary.org/obo/IEV_0003721 Gene expression of Argos by ETS1 http://purl.obolibrary.org/obo/IEV_0003699 Gene expression by ETS1/2 http://purl.obolibrary.org/obo/IEV_0003725 Gene expression of Kek by ETS1 http://purl.obolibrary.org/obo/IEV_0003699 Gene expression by ETS1/2 http://purl.obolibrary.org/obo/IEV_0003785 Gene expression of SRF by ETS1 http://purl.obolibrary.org/obo/IEV_0003699 Gene expression by ETS1/2 http://purl.obolibrary.org/obo/IEV_0003765 Degradation in lysosome http://purl.obolibrary.org/obo/IEV_0003710 Degradation http://purl.obolibrary.org/obo/IEV_0003715 Translocation of TGF alpha from Golgi to extracellular http://purl.obolibrary.org/obo/IEV_0003716 Translocation from Golgi to extracellular http://purl.obolibrary.org/obo/IEV_0003360 Gene expression of Sprouty1 by ETS1/2 http://purl.obolibrary.org/obo/IEV_0003717 Gene expression of Sprouty by ETS1/2 http://purl.obolibrary.org/obo/IEV_0003341 Gene expression of Sprouty2 by ETS1/2 http://purl.obolibrary.org/obo/IEV_0003717 Gene expression of Sprouty by ETS1/2 http://purl.obolibrary.org/obo/IEV_0003343 Nuclear export of mRNA (Sprouty2) http://purl.obolibrary.org/obo/IEV_0003718 Nuclear export of mRNA (Sprouty) http://purl.obolibrary.org/obo/IEV_0003362 Nuclear export of mRNA (Sprouty1) http://purl.obolibrary.org/obo/IEV_0003718 Nuclear export of mRNA (Sprouty) http://purl.obolibrary.org/obo/IEV_0003361 Transcription of Sprouty1 gene in nucleus http://purl.obolibrary.org/obo/IEV_0003719 Transcription of Sprouty gene in nucleus http://purl.obolibrary.org/obo/IEV_0003344 Transcription of Sprouty2 gene in nucleus http://purl.obolibrary.org/obo/IEV_0003719 Transcription of Sprouty gene in nucleus http://purl.obolibrary.org/obo/IEV_0003756 Translocation of Smo into the cilia http://purl.obolibrary.org/obo/IEV_0003755 Translocation into the cilia http://purl.obolibrary.org/obo/IEV_0003763 Translocation of Smo from plasma membrane to endosome http://purl.obolibrary.org/obo/IEV_0003764 Translocation from plasma membrane to endosome http://purl.obolibrary.org/obo/IEV_0003775 Binding of Ci/Gli, CBP and ptc gene promoter in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003773 Binding of Ci/Gli, CBP and Hedgehog target gene promoter in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003774 Binding of Ci/Gli, CBP and dpp gene promoter in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003773 Binding of Ci/Gli, CBP and Hedgehog target gene promoter in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003701 Negative regulation of FGFR1 signaling pathway http://purl.obolibrary.org/obo/IEV_0003801 Negative regulation of FGF receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0002477 Phosphorylation of PLC gamma by TRK_p in cytosol http://purl.obolibrary.org/obo/IEV_0003816 Phosphorylation of PLC gamma by receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0003818 Phosphorylation of PLC gamma1 by PDGF receptor in cytosol http://purl.obolibrary.org/obo/IEV_0003816 Phosphorylation of PLC gamma by receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000286 Phosphorylation of PLC gamma by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0001288 Phosphorylation of PLC by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0003816 Phosphorylation of PLC gamma by receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0003817 Phosphorylation of PLC gamma by tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0003817 Phosphorylation of PLC gamma by tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0003819 Phosphorylation of PLC by tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0001288 Phosphorylation of PLC by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0003819 Phosphorylation of PLC by tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000283 Binding of RTK and PLC gamma in cytosol http://purl.obolibrary.org/obo/IEV_0003822 Binding of PLC gamma and tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0003823 Binding of FGFR and Dof in cytosol http://purl.obolibrary.org/obo/IEV_0003824 Binding of FGFR and adaptor protein in cytosol http://purl.obolibrary.org/obo/IEV_0002490 Binding of FGFR_p and FRS2 in cytosol http://purl.obolibrary.org/obo/IEV_0003824 Binding of FGFR and adaptor protein in cytosol http://purl.obolibrary.org/obo/IEV_0002491 Phosphorylation of FRS2 by FGFR_p in cytosol http://purl.obolibrary.org/obo/IEV_0003825 Phosphorylation of adaptor protein by FGFR in cytosol http://purl.obolibrary.org/obo/IEV_0003826 Phosphorylation of Dof by FGFR in cytosol http://purl.obolibrary.org/obo/IEV_0003825 Phosphorylation of adaptor protein by FGFR in cytosol http://purl.obolibrary.org/obo/IEV_0003830 Hydrolysis of GTP by Ras and RasGAP in cytosol http://purl.obolibrary.org/obo/IEV_0003828 Hydrolysis of GTP by small GTPase and GAP in cytosol http://purl.obolibrary.org/obo/IEV_0002090 Hydrolysis of GTP by RapGAP in cytosol http://purl.obolibrary.org/obo/IEV_0003828 Hydrolysis of GTP by small GTPase and GAP in cytosol http://purl.obolibrary.org/obo/IEV_0000672 Hydrolysis of GTP by G alpha-GTP in cytosol http://purl.obolibrary.org/obo/IEV_0003829 Hydrolysis of GTP by trimeric G-protein in cytosol http://purl.obolibrary.org/obo/IEV_0003836 Movement of Ptc1 out of the cilia http://purl.obolibrary.org/obo/IEV_0003837 Translocation out of the cilia http://purl.obolibrary.org/obo/IEV_0001071 Binding of Cdk4/6 and cyclin D in cytosol http://purl.obolibrary.org/obo/IEV_0003860 Binding of CDK and cyclin in cytosol http://purl.obolibrary.org/obo/IEV_0001132 Binding of Cdc2 and CyclinA in cytosol http://purl.obolibrary.org/obo/IEV_0003860 Binding of CDK and cyclin in cytosol http://purl.obolibrary.org/obo/IEV_0001099 Binding of Cdk7 and Cyclin H in cytosol http://purl.obolibrary.org/obo/IEV_0003860 Binding of CDK and cyclin in cytosol http://purl.obolibrary.org/obo/IEV_0001101 Binding of Cdk2 and Cyclin A in cytosol http://purl.obolibrary.org/obo/IEV_0003860 Binding of CDK and cyclin in cytosol http://purl.obolibrary.org/obo/IEV_0001131 Binding of Cdc2 and CyclinB in cytosol http://purl.obolibrary.org/obo/IEV_0003860 Binding of CDK and cyclin in cytosol http://purl.obolibrary.org/obo/IEV_0001078 Binding of Cdk2 and cyclin E in cytosol http://purl.obolibrary.org/obo/IEV_0003860 Binding of CDK and cyclin in cytosol http://purl.obolibrary.org/obo/IEV_0002001 Binding of G alpha 12/13-GTP and RhoGEF in cytosol http://purl.obolibrary.org/obo/IEV_0003862 Binding of G alpha 12/13-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0002015 Binding of G alpha 12/13-GTP and PLC beta in cytosol http://purl.obolibrary.org/obo/IEV_0003862 Binding of G alpha 12/13-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0003864 Nuclear export of mRNA (Cip/Kip family) http://purl.obolibrary.org/obo/IEV_0003865 Nuclear export of mRNA (CKI) http://purl.obolibrary.org/obo/IEV_0003863 Nuclear export of mRNA (INK4 family) http://purl.obolibrary.org/obo/IEV_0003865 Nuclear export of mRNA (CKI) http://purl.obolibrary.org/obo/IEV_0001147 Transcription of p15 by Smad complex in nucleus http://purl.obolibrary.org/obo/IEV_0003866 Transcription of CKI by Smad complex in nucleus http://purl.obolibrary.org/obo/IEV_0001157 Transcription of p16 by Smad complex in nucleus http://purl.obolibrary.org/obo/IEV_0003866 Transcription of CKI by Smad complex in nucleus http://purl.obolibrary.org/obo/IEV_0001161 Transcription of p27 by Smad complex in nucleus http://purl.obolibrary.org/obo/IEV_0003866 Transcription of CKI by Smad complex in nucleus http://purl.obolibrary.org/obo/IEV_0001159 Transcription of p21 by Smad complex in nucleus http://purl.obolibrary.org/obo/IEV_0003866 Transcription of CKI by Smad complex in nucleus http://purl.obolibrary.org/obo/IEV_0001127 Translation of p21 in cytosol http://purl.obolibrary.org/obo/IEV_0003867 Translation of CKI in cytosol http://purl.obolibrary.org/obo/IEV_0001148 Translation of p15 in cytosol http://purl.obolibrary.org/obo/IEV_0003867 Translation of CKI in cytosol http://purl.obolibrary.org/obo/IEV_0001154 Translation of p16 in cytosol http://purl.obolibrary.org/obo/IEV_0003867 Translation of CKI in cytosol http://purl.obolibrary.org/obo/IEV_0001160 Translation of p27 in cytosol http://purl.obolibrary.org/obo/IEV_0003867 Translation of CKI in cytosol http://purl.obolibrary.org/obo/IEV_0000423 CoA ligation of 4-coumarate by 4CL in cytosol http://purl.obolibrary.org/obo/IEV_0000430 CoA ligation in cytosol http://purl.obolibrary.org/obo/IEV_0000422 CoA ligation of caffeic acid by 4CL in cytosol http://purl.obolibrary.org/obo/IEV_0000430 CoA ligation in cytosol http://purl.obolibrary.org/obo/IEV_0000424 CoA ligation of ferulate by 4CL in cytosol http://purl.obolibrary.org/obo/IEV_0000430 CoA ligation in cytosol http://purl.obolibrary.org/obo/IEV_0000426 CoA ligation of 5-Hydroxyferulate by 4CL in cytosol http://purl.obolibrary.org/obo/IEV_0000430 CoA ligation in cytosol http://purl.obolibrary.org/obo/IEV_0000431 CoA ligation inside of the plasma membrane http://purl.obolibrary.org/obo/IEV_0000430 CoA ligation in cytosol http://purl.obolibrary.org/obo/IEV_0002582 cell-to-cell movement of Hedgehog http://purl.obolibrary.org/obo/IEV_0002581 Intercellular transport http://purl.obolibrary.org/obo/IEV_0003300 1D-myo-Inositol 1,3,4-trisphosphate + H2O => 1D-myo-Inositol 3,4-bisphosphate + Orthophosphate( EC:3.1.3.57 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002750 myo-inositol phosphate + H2O = myo-inositol + Orthophosphate( EC:3.1.3.25 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002755 Nucleoside triphosphate + H2O = Nucleotide + diphosphate( EC:3.6.1.19 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002908 1-Phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + H2O => 1-Phosphatidyl-1D-myo-inositol 4,5-bisphosphate + Orthophosphate ( EC:3.1.3.67 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003207 L-O-Phospho-serine + H2O => L-Serine + Orthophosphate( EC:3.1.3.3 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002927 1-Phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O => 1-Phosphatidyl-1D-myo-inositol 4 phosphate + Orthophosphate( EC:3.1.3.36 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003099 1D-myo-Inositol 3,4-bisphosphate + H2O => 1D-myo-Inositol 3-phosphate + Orthophosphate( EC:3.1.3.66 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002752 nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate( EC:3.1.4.17 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002754 N-acyl-L-aspartate + H2O = Carboxylate + L-Aspartic acid( EC:3.5.1.15 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002758 dinucleotide + H2O = 2 mononucleotide( EC:3.6.1.9 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002788 L-Kynurenine + H2O => Anthranilic acid + L-Alanine( EC:3.7.1.3 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002802 D-Glucosamine 6-phosphate + H2O = D-Fructose 6-phosphate + NH3( EC:3.5.99.6 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002822 Adenosine + H2O => Inosine + NH3( EC:3.5.4.4 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002830 5,6-Dihydro-uracil + H2O = 3-Ureidopropionate( EC:3.5.2.2 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002849 5,6-Dihydro-thymine + H2O = 3-Ureidoisobutyrate( EC:3.5.2.2 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002877 ITP + H2O => IDP + Orthophosphate( EC:3.6.1.5 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002890 5,10-Methenyl-tetrahydro-folic acid + H2O = 10-Formyl-tetrahydro-folic acid + H+( EC:3.5.4.9 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002895 ADP-ribose + H2O => AMP + D-Ribose 5-phosphate( EC:3.6.1.13 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002897 Deoxy-adenosine + H2O => Deoxy-inosine + NH3( EC:3.5.4.4 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002958 GDP + H2O => GMP + Orthophosphate( EC:3.6.1.5 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002971 3-Ureidopropionate + H2O => beta-Alanine + CO2 + NH3( EC:3.5.1.6 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002993 dCMP + H2O => dUMP + NH3( EC:3.5.4.12 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003000 L-Glutamine + H2O = L-Glutamic acid + NH3( EC:3.5.1.2 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003014 Cytidine + H2O => Uridine + NH3( EC:3.5.4.5 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003015 ATP + H2O => ADP + Orthophosphate( EC:3.6.1.5 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003078 3-Ureidoisobutyrate + H2O => 3-Aminoisobutyric acid + CO2 + NH3( EC:3.5.1.6 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003081 GTP + H2O => 2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydro-pteridine triphosphate + Formic acid( EC:3.5.4.16 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003115 P1,P4-Bis(5'-guanosyl) tetraphosphate + H2O => GTP + GMP( EC:3.6.1.17 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003120 UDP + H2O => UMP + Orthophosphate( EC:3.6.1.5 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003126 5-Hydroxy-N-formyl-kynurenine + H2O => 5-Hydroxy-kynurenine + Formic acid( EC:3.5.1.9 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003182 D-Glucono-1,5-lactone 6-phosphate + H2O => 6-Phospho-D-gluconic acid( EC:3.1.1.31 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003211 Leukotriene A4 + H2O => Leukotriene B4( EC:3.3.2.6 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003219 ATP + H2O => ADP + Orthophosphate( EC:3.6.1.3 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003220 NAD+ + H2O => Nicotinamide + ADP-ribose( EC:3.2.2.5 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003224 AMP + H2O => IMP + NH3( EC:3.5.4.6 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003235 dUTP + H2O => dUMP + Pyrophosphate( EC:3.6.1.23 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003241 dTDP + H2O => dTMP + Orthophosphate( EC:3.6.1.5 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003255 ADP + H2O => AMP + Orthophosphate( EC:3.6.1.5 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003281 NADP+ + H2O => Nicotinamide + ADPribose 2'-phosphate( EC:3.2.2.5 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003286 P1,P4-Bis(5'-xanthosyl) tetraphosphate + H2O => XTP + XMP( EC:3.6.1.17 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003294 NADP+ + H2O => NAD+ + Orthophosphate( EC:3.1.3.- ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003301 CTP + H2O => CDP + Orthophosphate( EC:3.6.1.5 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003307 dTTP + H2O => dTDP + Orthophosphate( EC:3.6.1.5 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003318 IDP + H2O => IMP + Orthophosphate( EC:3.6.1.5 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003710 Degradation http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003844 GTP + H2O = Formamidopyrimidine nucleoside triphosphate( EC:3.5.4.16 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003080 (S)-Dihydro-orotic acid + H2O = N-Carbamoyl-L-aspartic acid( EC:3.5.2.3 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002757 Acylphosphate + H2O = Carboxylate + phosphate( EC:3.6.1.7 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0000673 Hydrolysis in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002924 3-Hydroxy-L-kynurenine + H2O => 3-Hydroxy-anthranilic acid + L-Alanine( EC:3.7.1.3 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002950 1D-myo-Inositol 1,4-bisphosphate + H2O => 1D-myo-Inositol 4-phosphate + Orthophosphate( EC:3.1.3.57 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002881 D-Fructose 2,6-bisphosphate + H2O => beta-D-Fructose 6-phosphate + Orthophosphate( EC:3.1.3.46 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0001165 Hydrolysis in Golgi http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003108 1D-myo-Inositol 1,4,5-trisphosphate + H2O => 1D-myo-Inositol 1,4-bisphosphate + Orthophosphate( EC:3.1.3.56 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002839 Allantoic acid + H2O => (-)-Ureidoglycolate + Urea( EC:3.5.3.4 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003186 IMP + H2O = 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide( EC:3.5.4.10 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003193 UTP + H2O => UDP + Orthophosphate( EC:3.6.1.5 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0001026 Hydrolysis in nucleus http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0000269 Hydrolysis in plasma membrane http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002753 Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides( EC:3.2.1.23 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002979 alpha-D-Glucose 6-phosphate + H2O => alpha-D-Glucose + Orthophosphate( EC:3.1.3.9 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003216 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + H2O => D-myo-Inositol 1,4,5-trisphosphate + 1,2-Diacyl-sn-glycerol( EC:3.1.4.11 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002956 beta-D-Fructose 1,6-bisphosphate + H2O => beta-D-Fructose 6-phosphate + Orthophosphate( EC:3.1.3.11 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002761 Preferential hydrolysis of the beta-Ala-|-His dipeptide (carnosine), and also anserine, Xaa-|-His dipeptides and other dipeptides including homocarnosine( EC:3.4.13.20 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0000685 Hydrolysis in cytosol http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002751 5'-ribonucleotide + H2O = ribonucleoside + phosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003192 1D-myo-Inositol 1,3,4,5-tetrakisphosphate + H2O => 1D-myo-Inositol 1,3,4-trisphosphate + Orthophosphate( EC:3.1.3.56 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003846 2,5-Diaminopyrimidine nucleoside triphosphate = 2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine( EC:3.5.4.16 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003845 Formamidopyrimidine nucleoside triphosphate + H2O = 2,5-Diaminopyrimidine nucleoside triphosphate + Formic acid( EC:3.5.4.16 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002836 S-Adenosyl-L-homocysteine + H2O => Adenosine + L-Homocysteine( EC:3.3.1.1 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002955 4-Fumaryl-acetoacetic acid + H2O => Fumaric acid + Acetoacetic acid( EC:3.7.1.2 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003089 (R)-S-Lactoyl-glutathione + H2O => Glutathione + (R)-Lactic acid( EC:3.1.2.6 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002876 Guanine + H2O => Xanthine + NH3( EC:3.5.4.3 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002931 L-Arginine + H2O => L-Ornithine + Urea( EC:3.5.3.1 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002756 nucleoside diphosphate + H2O = nucleotide + Orthophosphate( EC:3.6.1.6 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003261 GTP + H2O => GDP + Orthophosphate( EC:3.6.1.5 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0002970 Deoxy-cytidine + H2O => Deoxy-uridine + NH3( EC:3.5.4.5 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003055 CDP + H2O => CMP + Orthophosphate( EC:3.6.1.5 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0003847 2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate + H2O = 2,5-Diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine( EC:3.5.4.16 ) http://purl.obolibrary.org/obo/IEV_0000184 Hydrolysis http://purl.obolibrary.org/obo/IEV_0000939 Caspase cascade (through mitochondria) http://purl.obolibrary.org/obo/IEV_0000128 Caspase Cascade http://purl.obolibrary.org/obo/IEV_0000938 Caspase cascade (not through mitochondria) http://purl.obolibrary.org/obo/IEV_0000128 Caspase Cascade http://purl.obolibrary.org/obo/IEV_0001189 Negative regulation of Delta mediated Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0001188 Regulation of Delta mediated Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0001387 IKK activation signaling (through PKC theta and CARMA1:BCL10:MALT1) http://purl.obolibrary.org/obo/IEV_0001379 IKK activation signaling http://purl.obolibrary.org/obo/IEV_0003444 IKK activation signaling (through PKC beta and CARMA1:BCL10:MALT1) http://purl.obolibrary.org/obo/IEV_0001379 IKK activation signaling http://purl.obolibrary.org/obo/IEV_0002317 Activation of IKK complex by PKCs in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0000250 Phosphorylation of IKK complex by MAPKKK in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002633 Heterotrimeric GPCR signaling pathway (through Angiotensin and G alpha q) http://purl.obolibrary.org/obo/IEV_0000748 Heterotrimeric GPCR signaling pathway (through G alpha q and PLC beta) http://purl.obolibrary.org/obo/IEV_0002653 Heterotrimeric GPCR signaling pathway (through glutamate, G alpha q and PLC beta) http://purl.obolibrary.org/obo/IEV_0000748 Heterotrimeric GPCR signaling pathway (through G alpha q and PLC beta) http://purl.obolibrary.org/obo/IEV_0003684 Insulin receptor family signaling pathway http://purl.obolibrary.org/obo/IEV_0000830 RTK signaling pathway http://purl.obolibrary.org/obo/IEV_0002338 BMP2 signaling pathway(through TAK1) http://purl.obolibrary.org/obo/IEV_0000863 BMP signaling pathway http://purl.obolibrary.org/obo/IEV_0002337 BMP2 signaling pathway(through Smad) http://purl.obolibrary.org/obo/IEV_0000863 BMP signaling pathway http://purl.obolibrary.org/obo/IEV_0002501 Regulation of BMP2 signaling pathway (through Smad) http://purl.obolibrary.org/obo/IEV_0000882 Regulation of BMP signaling pathway http://purl.obolibrary.org/obo/IEV_0002504 Regulation of BMP2 signaling pathway (through TAK1) http://purl.obolibrary.org/obo/IEV_0000882 Regulation of BMP signaling pathway http://purl.obolibrary.org/obo/IEV_0000249 Reduction in cytosol http://purl.obolibrary.org/obo/IEV_0000916 Reduction http://purl.obolibrary.org/obo/IEV_0000279 Reduction in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000916 Reduction http://purl.obolibrary.org/obo/IEV_0001060 Farnesylation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000919 Farnesylation http://purl.obolibrary.org/obo/IEV_0000440 Farnesylation in cytosol http://purl.obolibrary.org/obo/IEV_0000919 Farnesylation http://purl.obolibrary.org/obo/IEV_0000977 Inactivation of Bcl-2 family by pro-apoptotic factor in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000967 Inactivation in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000970 Inactivation of Bid by Bcl-2 in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000967 Inactivation in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0003413 Caspase3 activation signaling (through mitochondria) http://purl.obolibrary.org/obo/IEV_0001006 Caspase3/6/7 activation signaling (through mitochondria) http://purl.obolibrary.org/obo/IEV_0003414 Caspase3 homodimer formation in cytosol http://purl.obolibrary.org/obo/IEV_0001007 Caspase3/6/7 homodimer formation in cytosol http://purl.obolibrary.org/obo/IEV_0001487 Positive regulation of AKT(PKB) activation signaling http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001486 Negative regulation of AKT(PKB) activation signaling http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000181 Internalization of TGF beta receptor http://purl.obolibrary.org/obo/IEV_0001505 Receptor internalization http://purl.obolibrary.org/obo/IEV_0001965 Internalization of Arrow/LRP5/6 http://purl.obolibrary.org/obo/IEV_0001505 Receptor internalization http://purl.obolibrary.org/obo/IEV_0001102 Transcription by E2F-1 in nucleus http://purl.obolibrary.org/obo/IEV_0001076 Transcription by E2F in nucleus http://purl.obolibrary.org/obo/IEV_0003246 Pyridoxal + O2 + H2O => 4-Pyridoxic acid + H2O2( EC:1.2.3.1 ) http://purl.obolibrary.org/obo/IEV_0002731 Aldehyde + H2O + O2 = Carboxylate + H2O2( EC:1.2.3.1 ) http://purl.obolibrary.org/obo/IEV_0003289 5-Hydroxy-indole-acetaldehyde + H2O + O2 => 5-Hydroxy-indole-acetic acid + H2O2( EC:1.2.3.1 ) http://purl.obolibrary.org/obo/IEV_0002731 Aldehyde + H2O + O2 = Carboxylate + H2O2( EC:1.2.3.1 ) http://purl.obolibrary.org/obo/IEV_0000748 Heterotrimeric GPCR signaling pathway (through G alpha q and PLC beta) http://purl.obolibrary.org/obo/IEV_0002634 Heterotrimeric GPCR signaling pathway (through G alpha q) http://purl.obolibrary.org/obo/IEV_0000724 Activation of rhodopsin by photon in extracellular http://purl.obolibrary.org/obo/IEV_0000725 Activation in extracellular http://purl.obolibrary.org/obo/IEV_0003491 Activation of serine protease in extracellular http://purl.obolibrary.org/obo/IEV_0000725 Activation in extracellular http://purl.obolibrary.org/obo/IEV_0003504 Activation of Spaetzle by serine protease in extracellular http://purl.obolibrary.org/obo/IEV_0000725 Activation in extracellular http://purl.obolibrary.org/obo/IEV_0001037 Binding outside the ER membrane http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001368 Phosphorylation of Vav by ZAP-70 in cytosol http://purl.obolibrary.org/obo/IEV_0000264 Phosphorylation of Vav by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000626 Phosphorylation of Vav by Syk in cytosol http://purl.obolibrary.org/obo/IEV_0000264 Phosphorylation of Vav by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000305 199 medium http://purl.obolibrary.org/obo/IEV_0000342 Fibroblast medium http://purl.obolibrary.org/obo/IEV_0002175 Binding of STAT3:p300:Smad1:Smad4 complex and GFAP promoter in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000156 Binding of R-Smad:Smad4 complex, Coactivator and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002522 Binding of Smad1:Smad4:OAZ complex and BRE in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000156 Binding of R-Smad:Smad4 complex, Coactivator and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003154 Acetyl phosphate + H2O = Acetic acid + Orthophosphate( EC:3.6.1.7 ) http://purl.obolibrary.org/obo/IEV_0002757 Acylphosphate + H2O = Carboxylate + phosphate( EC:3.6.1.7 ) http://purl.obolibrary.org/obo/IEV_0000236 Phosphorylation of MKK3/4/6 by MAPKKK in cytosol http://purl.obolibrary.org/obo/IEV_0000474 Phosphorylation of MAPKK by MAPKKK in cytosol http://purl.obolibrary.org/obo/IEV_0003389 Phosphorylation of MKK by TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000474 Phosphorylation of MAPKK by MAPKKK in cytosol http://purl.obolibrary.org/obo/IEV_0003390 Phosphorylation of MKK by MEKK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000474 Phosphorylation of MAPKK by MAPKKK in cytosol http://purl.obolibrary.org/obo/IEV_0000475 Phosphorylation of MEK1/2(MKK1/2) by MAPKKK in cytosol http://purl.obolibrary.org/obo/IEV_0000474 Phosphorylation of MAPKK by MAPKKK in cytosol http://purl.obolibrary.org/obo/IEV_0002925 UTP + AMP = UDP + ADP( EC:2.7.4.10 ) http://purl.obolibrary.org/obo/IEV_0002747 Nucleoside triphosphate + AMP = Nucleoside diphosphate + ADP( EC:2.7.4.10 ) http://purl.obolibrary.org/obo/IEV_0003822 Binding of PLC gamma and tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0003820 Binding of PLC and tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000069 Cellular event http://purl.obolibrary.org/obo/IEV_0000003 Biological event http://purl.obolibrary.org/obo/IEV_0000071 Molecular event http://purl.obolibrary.org/obo/IEV_0000003 Biological event http://purl.obolibrary.org/obo/IEV_0000082 Organism event http://purl.obolibrary.org/obo/IEV_0000003 Biological event http://purl.obolibrary.org/obo/IEV_0001330 Physiological event http://purl.obolibrary.org/obo/IEV_0000003 Biological event http://purl.obolibrary.org/obo/IEV_0003769 Phosphorylation of Cos2 by Fu in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003556 Phosphorylation of IRS-1 by IGF-1 receptor in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003770 Phosphorylation of Sufu by Fu in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000888 Phosphorylation of R-Smad:Smad4 by MAPK in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000797 Phosphorylation of PPAR by kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002600 Phosphorylation of Ci/Gli by GSK3 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000061 Phosphorylation of 4EBP by TOR of TORC1 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002598 Phosphorylation of Ci/Gli by CK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000651 Phosphorylation of MLC by MLCK in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001253 Phosphorylation of CD3 zeta by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000960 Phosphorylation of DLC1 by MAPK8 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002083 Phosphorylation of Cbl by Src in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000446 Phosphorylation of STAT by JAK_p in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000131 Phosphorylation of Bad by RSK in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000209 Phosphorylation of NIK by TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000265 Phosphorylation of Vav by PI3K in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000370 Phosphorylation of Cdk4/6 by CAK in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000401 Phosphorylation of Bad by PKA in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000495 Phosphorylation of IRS by insulin receptor in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000595 Phosphorylation of p130Cas by Src family in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000601 Phosphorylation of Shc by Fyn in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000624 Phosphorylation outside the mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000658 Phosphorylation of MLCK by PAK in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001133 Phosphorylation of Cdc2 by Cdk7 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001270 Phosphorylation of STAT by MAPK in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001612 Phosphorylation of Src family by non-receptor kinase and inactive conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001734 Phosphorylation of HDAC7 by CaMKI in cytosol http://purl.obolibrary.org/obo/IEV_0001700 Phosphorylation of HDAC5/7 by CaMK in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0001743 Phosphorylation of GSK3beta by AKT in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001809 Phosphorylation of NLK by TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001810 Phosphorylation of TCF by NLK in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001950 Phosphorylation of Arrow/LRP5/6 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001969 Phosphorylation of beta-catenin by CK1alpha in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001970 Phosphorylation of beta-catenin by GSK-3 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001991 Phosphorylation of PI3K by JAK3_p in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002082 Phosphorylation of Src by PKA in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002307 Phosphorylation of BLNK by Syk in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002336 Phosphorylation of PI3K by JAK1_p in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002412 Phosphorylation of p38 by KDR_p in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002413 Phosphorylation of MAPKAPK2/3 by p38_p in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002414 Phosphorylation of HSP27 by MAPKAPK2/3_p in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002415 Phosphorylation of Akt by protein kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002421 Phosphorylation of CREB by PKA in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002423 Phosphorylation of DARPP-32 by PKA in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002426 Phosphorylation of L-type Ca2+ channel by PKA in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002427 Phosphorylation of NMDA glutamate receptor by PKA in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002428 Phosphorylation of DARPP-32 by CDK5 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002493 Phosphorylation of Gab1 by FRS2 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002520 Phosphorylation of Smad1 by BMP receptor I_p in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002631 Phosphorylation of Shc by RTK in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003340 Phosphorylation of Sprouty2 by FGFR1 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003359 Phosphorylation of Sprouty1 by FGFR1 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003407 Phosphorylation of 14-3-3 by JNK_p in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003419 Phosphorylation of IKK complex by RIP in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003441 Phosphorylation of PI3K by JAK2_p in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003442 Phosphorylation of CARMA1 by PKC theta in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003540 Phosphorylation of TRAF2 by Pelle_p in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003583 Phosphorylation of TGF beta superfamily receptor I by TGF beta superfamily receptor II in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003584 Phosphorylation of R-Smad by TGF beta superfamily receptor I in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003616 Phosphorylation of Shc by JAK2_p in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003633 Phosphorylation of TSC2 by AKT in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003638 Phosphorylation of p70S6K by TOR of TORC1 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003641 Phosphorylation of S6RP by p70S6K in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003647 Phosphorylation of TSC2 by AMPK in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003648 Phosphorylation of TSC2 by GSK3b in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003738 Phosphorylation of Sprouty by EGFR in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003750 Phosphorylation of Smo by PKA in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003819 Phosphorylation of PLC by tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003825 Phosphorylation of adaptor protein by FGFR in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003902 Phosphorylation of Nck by PDGF receptor in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003904 Phosphorylation of STAT5 by PDGF receptor in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003469 Phosphorylation of Relish by IKK in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000264 Phosphorylation of Vav by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000030 Phosphorylation of DSH by CK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000594 Phosphorylation of FAK by Src family in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000573 Phosphorylation of ZAP-70 by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003753 Phosphorylation of Smo by GRK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000402 Phosphorylation of caspase9 by AKT in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000053 Phosphorylation of cytokine receptor by Jak in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000964 Phosphorylation of DLC2 by MAPK8 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000180 Phosphorylation of Bcl-2 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003384 Phosphorylation of TAB2 and TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001480 Phosphorylation of CD28 by Src family in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000197 Phosphorylation of IRAK1 by IRAK4 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000617 Phosphorylation of ERK by FAK in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000213 Phosphorylation of I-kappaB_p by IKK complex_p in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000596 Phosphorylation of paxillin by Src family in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000263 Phosphorylation of LAT by ZAP-70_p in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003683 Phosphorylation of FOXO by AKT in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000654 Phosphorylation of MLCK by ERK in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003668 Phosphorylation of PRAS40 by AKT in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002086 Phosphorylation of MAPKKK by non-receptor serine/threonine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000527 Phosphorylation of SLP-76 by ZAP-70_p in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003646 Phosphorylation of Glycogen synthase by GSK3b in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003751 Phosphorylation of Smo by CK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0002597 Phosphorylation of Ci/Gli by PKA in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000514 Phosphorylation of PAG/Cbp by Fyn in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000653 Phosphorylation of cofilin by LIM-kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0003445 Phosphorylation of CARMA1 by PKC beta in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000652 Phosphorylation of LIM-kinase by p160ROCK in cytosol http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000783 Gene expression by NF-kappaB http://purl.obolibrary.org/obo/IEV_0000233 Gene expression by transcriptional regulator http://purl.obolibrary.org/obo/IEV_0001110 Gene expression by p53 http://purl.obolibrary.org/obo/IEV_0000233 Gene expression by transcriptional regulator http://purl.obolibrary.org/obo/IEV_0001142 Gene expression by Smad complex http://purl.obolibrary.org/obo/IEV_0000233 Gene expression by transcriptional regulator http://purl.obolibrary.org/obo/IEV_0002102 Gene expression by STAT dimer http://purl.obolibrary.org/obo/IEV_0000233 Gene expression by transcriptional regulator http://purl.obolibrary.org/obo/IEV_0002280 Gene expression by beta-catenin:TCF complex http://purl.obolibrary.org/obo/IEV_0000233 Gene expression by transcriptional regulator http://purl.obolibrary.org/obo/IEV_0002283 Gene expression by beta-catenin:TCF complex and Smad4 http://purl.obolibrary.org/obo/IEV_0000233 Gene expression by transcriptional regulator http://purl.obolibrary.org/obo/IEV_0003628 Gene expression by FOXO http://purl.obolibrary.org/obo/IEV_0000233 Gene expression by transcriptional regulator http://purl.obolibrary.org/obo/IEV_0003778 Gene expression by Ci/Gli http://purl.obolibrary.org/obo/IEV_0000233 Gene expression by transcriptional regulator http://purl.obolibrary.org/obo/IEV_0003387 Gene expression by AP-1 http://purl.obolibrary.org/obo/IEV_0000233 Gene expression by transcriptional regulator http://purl.obolibrary.org/obo/IEV_0003698 Gene expression by ets domain transcription factor http://purl.obolibrary.org/obo/IEV_0000233 Gene expression by transcriptional regulator http://purl.obolibrary.org/obo/IEV_0002625 Nuclear import of ERK1/2_p http://purl.obolibrary.org/obo/IEV_0000466 Nuclear import of ERK_p http://purl.obolibrary.org/obo/IEV_0000754 G alpha q-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0000671 G alpha-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0000388 Nuclear import of Cdk4:cyclin D http://purl.obolibrary.org/obo/IEV_0001072 Nuclear import of Cdk4/6_p:cyclin D http://purl.obolibrary.org/obo/IEV_0000631 GDP-GTP exchange of Rap1 by C3G in cytosol http://purl.obolibrary.org/obo/IEV_0000605 GDP-GTP exchange in cytosol http://purl.obolibrary.org/obo/IEV_0000604 GDP-GTP exchange of Ras by Sos in cytosol http://purl.obolibrary.org/obo/IEV_0000605 GDP-GTP exchange in cytosol http://purl.obolibrary.org/obo/IEV_0000832 GDP-GTP exchange of Rac by Sos1 in cytosol http://purl.obolibrary.org/obo/IEV_0000605 GDP-GTP exchange in cytosol http://purl.obolibrary.org/obo/IEV_0000634 GDP-GTP exchange of Rac by Dock180 in cytosol http://purl.obolibrary.org/obo/IEV_0000605 GDP-GTP exchange in cytosol http://purl.obolibrary.org/obo/IEV_0002071 GDP-GTP exchange of Rap1 by Epac1 in cytosol http://purl.obolibrary.org/obo/IEV_0000605 GDP-GTP exchange in cytosol http://purl.obolibrary.org/obo/IEV_0002200 GDP-GTP exchange of Ras by RasGRP in cytosol http://purl.obolibrary.org/obo/IEV_0000605 GDP-GTP exchange in cytosol http://purl.obolibrary.org/obo/IEV_0002530 GDP-GTP exchange of Rac1 by RhoGEF in cytosol http://purl.obolibrary.org/obo/IEV_0000605 GDP-GTP exchange in cytosol http://purl.obolibrary.org/obo/IEV_0002531 GDP-GTP exchange of Cdc42 by RhoGEF in cytosol http://purl.obolibrary.org/obo/IEV_0000605 GDP-GTP exchange in cytosol http://purl.obolibrary.org/obo/IEV_0002532 GDP-GTP exchange of RhoA by RhoGEF in cytosol http://purl.obolibrary.org/obo/IEV_0000605 GDP-GTP exchange in cytosol http://purl.obolibrary.org/obo/IEV_0003635 GDP-GTP exchange of Rheb in cytosol http://purl.obolibrary.org/obo/IEV_0000605 GDP-GTP exchange in cytosol http://purl.obolibrary.org/obo/IEV_0000663 GDP-GTP exchange of G alpha in cytosol http://purl.obolibrary.org/obo/IEV_0000605 GDP-GTP exchange in cytosol http://purl.obolibrary.org/obo/IEV_0000627 GDP-GTP exchange of Rac by Vav in cytosol http://purl.obolibrary.org/obo/IEV_0000605 GDP-GTP exchange in cytosol http://purl.obolibrary.org/obo/IEV_0000828 GDP-GTP exchange of Ral by RalGDS in cytosol http://purl.obolibrary.org/obo/IEV_0000605 GDP-GTP exchange in cytosol http://purl.obolibrary.org/obo/IEV_0000163 fMLP signaling pathway http://purl.obolibrary.org/obo/IEV_0000661 GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0002635 Heterotrimeric GPCR signaling pathway (through G alpha o) http://purl.obolibrary.org/obo/IEV_0000661 GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0002636 Heterotrimeric GPCR signaling pathway (through G alpha t) http://purl.obolibrary.org/obo/IEV_0000661 GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0002634 Heterotrimeric GPCR signaling pathway (through G alpha q) http://purl.obolibrary.org/obo/IEV_0000661 GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0000691 Heterotrimeric GPCR signaling pathway (through G alpha s) http://purl.obolibrary.org/obo/IEV_0000661 GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0000692 Heterotrimeric GPCR signaling pathway (through G alpha i) http://purl.obolibrary.org/obo/IEV_0000661 GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0001693 Endothelin receptor signaling http://purl.obolibrary.org/obo/IEV_0000661 GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0000722 GDP-GTP exchange of G alpha s in cytosol http://purl.obolibrary.org/obo/IEV_0000663 GDP-GTP exchange of G alpha in cytosol http://purl.obolibrary.org/obo/IEV_0000726 GDP-GTP exchange of G alpha t in cytosol http://purl.obolibrary.org/obo/IEV_0000663 GDP-GTP exchange of G alpha in cytosol http://purl.obolibrary.org/obo/IEV_0000776 GDP-GTP exchange of G alpha o in cytosol http://purl.obolibrary.org/obo/IEV_0000663 GDP-GTP exchange of G alpha in cytosol http://purl.obolibrary.org/obo/IEV_0000741 GDP-GTP exchange of G alpha q in cytosol http://purl.obolibrary.org/obo/IEV_0000663 GDP-GTP exchange of G alpha in cytosol http://purl.obolibrary.org/obo/IEV_0000720 GDP-GTP exchange of G alpha i in cytosol http://purl.obolibrary.org/obo/IEV_0000663 GDP-GTP exchange of G alpha in cytosol http://purl.obolibrary.org/obo/IEV_0000735 G alpha t-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0000733 Negative regulation of heterotrimeric GPCR signaling pathway (through photon, rhodopsin, G alpha t and PDE) http://purl.obolibrary.org/obo/IEV_0000701 G alpha i-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0000671 G alpha-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0000702 G alpha s-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0000671 G alpha-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002637 Heterotrimeric GPCR signaling pathway (through Dopamine and G alpha s) http://purl.obolibrary.org/obo/IEV_0000691 Heterotrimeric GPCR signaling pathway (through G alpha s) http://purl.obolibrary.org/obo/IEV_0000707 Heterotrimeric GPCR signaling pathway (through G alpha s, cholera toxin, adenylate cyclase and cAMP) http://purl.obolibrary.org/obo/IEV_0000691 Heterotrimeric GPCR signaling pathway (through G alpha s) http://purl.obolibrary.org/obo/IEV_0000276 Heterotrimeric GPCR signaling pathway (through PACAP, G alpha s and adenylate cyclase, cAMP and PKA) http://purl.obolibrary.org/obo/IEV_0000691 Heterotrimeric GPCR signaling pathway (through G alpha s) http://purl.obolibrary.org/obo/IEV_0000718 ADP ribosylation of G alpha i by pertussis toxin in cytosol http://purl.obolibrary.org/obo/IEV_0000710 ADP ribosylation in cytosol http://purl.obolibrary.org/obo/IEV_0000708 ADP-ribosylation of G alpha s by cholera toxin in cytosol http://purl.obolibrary.org/obo/IEV_0000710 ADP ribosylation in cytosol http://purl.obolibrary.org/obo/IEV_0000788 Binding of RelA and PPAR in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001201 Binding of Estrogen and Estrogen receptor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001789 Homodimerization of Androgen receptor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001790 Homodimerization of Estrogen receptor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000035 Binding of beta-catenin and TCF in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000795 Binding of PPAR and transcription factor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001194 Binding of Mint and CSL in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001206 Complex formation of Estrogen receptor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001215 Transcription factor complex formation with Estrogen receptor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001711 Binding of transcription factor and Crm1 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001769 Binding of Androgen and Androgen receptor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001788 Binding of Androgen receptor and HDAC in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001832 Binding of trans-activator and co-repressor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001933 Binding of Mdm2 and Mdm4 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001934 Binding of Mdm2 and ARF in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001956 Binding of Pygopus, Legless and beta-catenin:TCF complex in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001957 Binding of CBP and beta-catenin in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001972 Binding of Chibby and beta-catenin in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001973 Binding of ICAT and beta-catenin in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001975 Binding of Groucho and TCF in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002178 Binding of STAT3 and p300 and Smad1 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002272 Binding of beta-catenin, TCF and Smad4 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002274 Binding of beta-catenin:TCF:Smad4 and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002521 Binding of Smad1_p:Smad4 and OAZ in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002621 Binding of Notch (ICN):CSL and Nrarp in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000792 Binding of PPAR and nuclear receptor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001958 Binding of Brg1 and beta-catenin:TCF complex in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002187 Binding of R-Smad:Smad4 complex, Corepressor, HDAC and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003777 Binding of Ci/GliR and Hedgehog target gene promoter in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001819 Complex formation of beta catenin, TCF/LEF, Legless, Pygopus, etc. in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001174 Binding of Notch (NIC) and transcription factor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001075 Binding of E2F and DP-1 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001703 Binding of HDAC5/7 and MEF2 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002098 Binding of transcription factor and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001761 Sumoylation of Smad3 by PIAS4 in cytosol http://purl.obolibrary.org/obo/IEV_0001055 SUMOylation in cytosol http://purl.obolibrary.org/obo/IEV_0001183 Binding of Notch1 and Fringe in Golgi http://purl.obolibrary.org/obo/IEV_0001184 Binding in Golgi http://purl.obolibrary.org/obo/IEV_0000060 Grb2-Sos-Ras-PI3K signaling http://purl.obolibrary.org/obo/IEV_0001258 Ras mediated signaling http://purl.obolibrary.org/obo/IEV_0002290 Regulation of B cell receptor signaling (through IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0001273 Regulation of B cell receptor signaling http://purl.obolibrary.org/obo/IEV_0001304 CaMKII activation signaling http://purl.obolibrary.org/obo/IEV_0001302 Calcium ion dependent protein activation signaling http://purl.obolibrary.org/obo/IEV_0001303 Calcineurin activation signaling http://purl.obolibrary.org/obo/IEV_0001302 Calcium ion dependent protein activation signaling http://purl.obolibrary.org/obo/IEV_0000298 MEBM (medium) http://purl.obolibrary.org/obo/IEV_0000353 Mammary epithelial cell medium http://purl.obolibrary.org/obo/IEV_0000297 MEGM (medium) http://purl.obolibrary.org/obo/IEV_0000353 Mammary epithelial cell medium http://purl.obolibrary.org/obo/IEV_0000302 PrEBM (medium) http://purl.obolibrary.org/obo/IEV_0000354 Human prostate epithelial cell medium http://purl.obolibrary.org/obo/IEV_0000301 PrEGM (medium) http://purl.obolibrary.org/obo/IEV_0000354 Human prostate epithelial cell medium http://purl.obolibrary.org/obo/IEV_0001565 Heat shock treatment http://purl.obolibrary.org/obo/IEV_0000379 Heat treatment http://purl.obolibrary.org/obo/IEV_0000065 PLC beta signaling http://purl.obolibrary.org/obo/IEV_0000471 PLC signaling http://purl.obolibrary.org/obo/IEV_0000467 PLC gamma signaling http://purl.obolibrary.org/obo/IEV_0000471 PLC signaling http://purl.obolibrary.org/obo/IEV_0001223 Binding of Src and Estrogen receptor beta:MNAR http://purl.obolibrary.org/obo/IEV_0000186 Binding in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0001224 Binding of Estrogen receptor and MNAR http://purl.obolibrary.org/obo/IEV_0000186 Binding in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0001237 Binding of Glutamate and AMPA receptor http://purl.obolibrary.org/obo/IEV_0000186 Binding in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0001795 Binding of calcineurin and CSK http://purl.obolibrary.org/obo/IEV_0000186 Binding in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0001985 Binding of G beta:G gamma and PI3K gamma http://purl.obolibrary.org/obo/IEV_0000186 Binding in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0002189 Binding of Smad2, smurf2 and SnoN http://purl.obolibrary.org/obo/IEV_0000186 Binding in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0001794 Binding of calcineurin and FK506 http://purl.obolibrary.org/obo/IEV_0000186 Binding in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0001236 Binding of Glutamate and NMDA receptor http://purl.obolibrary.org/obo/IEV_0000186 Binding in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0001185 Binding of Notch and Fringe http://purl.obolibrary.org/obo/IEV_0000186 Binding in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0001868 Positive regulation of HDAC nuclear export signaling http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001869 Negative regulation of HDAC nuclear export signaling http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001871 Negative regulation of HDAC nuclear import signaling http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001872 Positive regulation of HDAC nuclear import signaling http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0003712 Translocation of TGF alpha:Star from ER to Golgi http://purl.obolibrary.org/obo/IEV_0002612 Translocation from ER to Golgi http://purl.obolibrary.org/obo/IEV_0002615 Translocation of Arrow/LRP5/6 from ER to Golgi http://purl.obolibrary.org/obo/IEV_0002612 Translocation from ER to Golgi http://purl.obolibrary.org/obo/IEV_0003740 Proteasome degradation of Sprouty in cytosol http://purl.obolibrary.org/obo/IEV_0000021 Proteasome degradation in cytosol http://purl.obolibrary.org/obo/IEV_0000210 Proteasome degradation of I-kappaB in cytosol http://purl.obolibrary.org/obo/IEV_0000021 Proteasome degradation in cytosol http://purl.obolibrary.org/obo/IEV_0000564 Proteasome degradation of ZAP-70 by 26S proteasome in cytosol http://purl.obolibrary.org/obo/IEV_0000021 Proteasome degradation in cytosol http://purl.obolibrary.org/obo/IEV_0000571 Proteasome degradation of Lck by 26S proteasome in cytosol http://purl.obolibrary.org/obo/IEV_0000021 Proteasome degradation in cytosol http://purl.obolibrary.org/obo/IEV_0001085 Proteasome degradation of cyclin E in cytosol http://purl.obolibrary.org/obo/IEV_0000021 Proteasome degradation in cytosol http://purl.obolibrary.org/obo/IEV_0001741 Proteasome degradation of beta catenin by 26S proteasome in cytosol http://purl.obolibrary.org/obo/IEV_0000021 Proteasome degradation in cytosol http://purl.obolibrary.org/obo/IEV_0001931 Proteasome degradation of Mdm4 in cytosol http://purl.obolibrary.org/obo/IEV_0000021 Proteasome degradation in cytosol http://purl.obolibrary.org/obo/IEV_0002222 Proteasome degradation of cytokine receptor by 26S proteasome in cytosol http://purl.obolibrary.org/obo/IEV_0000021 Proteasome degradation in cytosol http://purl.obolibrary.org/obo/IEV_0002518 Proteasome degradation of Cactus_p by 26S proteasome in cytosol http://purl.obolibrary.org/obo/IEV_0000021 Proteasome degradation in cytosol http://purl.obolibrary.org/obo/IEV_0001109 Proteasome degradation of p53 in cytosol http://purl.obolibrary.org/obo/IEV_0000021 Proteasome degradation in cytosol http://purl.obolibrary.org/obo/IEV_0000207 Proteasome degradation of IRAK1_p in cytosol http://purl.obolibrary.org/obo/IEV_0000021 Proteasome degradation in cytosol http://purl.obolibrary.org/obo/IEV_0000568 Proteasome degradation of Syk by 26S proteasome in cytosol http://purl.obolibrary.org/obo/IEV_0000021 Proteasome degradation in cytosol http://purl.obolibrary.org/obo/IEV_0000565 Proteasome degradation of CD3 by 26S proteasome in cytosol http://purl.obolibrary.org/obo/IEV_0000021 Proteasome degradation in cytosol http://purl.obolibrary.org/obo/IEV_0001056 Proteasome degradation of cyclin D in cytosol http://purl.obolibrary.org/obo/IEV_0000021 Proteasome degradation in cytosol http://purl.obolibrary.org/obo/IEV_0003418 Proteasome degradation of c-FLIP in cytosol http://purl.obolibrary.org/obo/IEV_0000021 Proteasome degradation in cytosol http://purl.obolibrary.org/obo/IEV_0000899 Proteasome degradation of R-Smad by 26S proteasome in cytosol http://purl.obolibrary.org/obo/IEV_0000021 Proteasome degradation in cytosol http://purl.obolibrary.org/obo/IEV_0002591 Binding of Hedgehog and Ptc in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0000154 Binding of TGF beta superfamily and TGF beta superfamily receptor I/II in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0000191 Binding of IL1 and IL1R complex in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0000579 Binding of extracellular matrix and Integrin complex in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0003762 Binding of Hedgehog and Ihog/Boi/Cdo/Boc in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0003466 Binding of PGRP-LE and PGN in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0000240 Binding of LPS and TLR4:MD-2:CD14 in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0000251 Binding of TNF alpha homotrimer and TNFR1 in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0000259 Binding of antigen, TCR-CD3 complex and CD4 in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0000488 Binding of insulin and insulin receptor in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0000511 Binding of CD4 and Lck in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0000521 Binding of antigen and MHC II in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0000804 Binding of TNF alpha homotrimer and TNFR2 in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0000842 Binding of RTK-ligand and RTK in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0000923 Binding of FasL and Fas in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0000935 Binding of DR4/5 and APO-2L in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0001694 Binding of endothelin and endothelin receptor in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0001814 Binding of SFRP and Wnt receptor in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0001816 Binding of Wnt and Wnt receptor in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0001817 Binding of WIF and Wnt receptor in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0001818 Binding of Dkk and Wnt receptor in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0001959 Binding of Wnt and WIF in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0001960 Binding of Wnt and SFRP in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0001964 Binding of Wise and Arrow/LRP5/6 in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0002278 Binding of Wnt and HSPG in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0002279 Binding of wingless and Dally in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0002416 Binding of Dopamine and D1-like receptor in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0002517 Binding of PSH and NEC in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0003457 Binding of PGRP-LC and LPS in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0003465 Binding of PGRP-LC and PGN in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0003494 Binding of GNBP3 and beta1-3 glucan in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0003497 Binding of PGRP-SA:GNBP1 and PGN in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0003498 Binding of PGRP-SD and PGN in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0003500 Binding of Toll and Spaetzle in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0003561 Binding of IGF-1 and IGFBP in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0003711 Binding TGF alpha and Star in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0003737 Binding of Argos and TGF alpha in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0003886 Binding of Tsg, Chordin and BMP in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0000278 Binding of CD28 and CD80/CD86 in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0001168 Binding of Notch and DSL ligand in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0003496 Binding of PGRP-SA and GNBP1 in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0001278 Binding of antigen and BCR complex in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0000580 Binding of extracellular matrix protein and integrin complex in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0000662 Binding of GPCR ligand and GPCR in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0003761 Binding of Hedgehog and Hip in extracellular http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0003614 Binding of IL-13 and IL-13 receptor in extracellular http://purl.obolibrary.org/obo/IEV_0003613 Negative regulation of IL13 signaling pathway (JAK1, TYK2, STAT6) http://purl.obolibrary.org/obo/IEV_0001690 Negative regulation of caloric restriction - cell survival signaling http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001691 Positive regulation of caloric restriction - cell survival signaling http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0002965 ADP + Reduced thioredoxin => dADP + H2O + Oxidized thioredoxin( EC:1.17.4.1 ) http://purl.obolibrary.org/obo/IEV_0002728 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin( EC:1.17.4.1 ) http://purl.obolibrary.org/obo/IEV_0003247 UDP + Reduced thioredoxin => dUDP + H2O + Oxidized thioredoxin( EC:1.17.4.1 ) http://purl.obolibrary.org/obo/IEV_0002728 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin( EC:1.17.4.1 ) http://purl.obolibrary.org/obo/IEV_0003053 CDP + Reduced thioredoxin => dCDP + H2O + Oxidized thioredoxin( EC:1.17.4.1 ) http://purl.obolibrary.org/obo/IEV_0002728 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin( EC:1.17.4.1 ) http://purl.obolibrary.org/obo/IEV_0003034 GDP + Reduced thioredoxin => dGDP + H2O + Oxidized thioredoxin( EC:1.17.4.1 ) http://purl.obolibrary.org/obo/IEV_0002728 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin( EC:1.17.4.1 ) http://purl.obolibrary.org/obo/IEV_0000374 Photoperiod treatment http://purl.obolibrary.org/obo/IEV_0000372 Radiation treatment http://purl.obolibrary.org/obo/IEV_0000373 Wavelength of light treatment http://purl.obolibrary.org/obo/IEV_0000372 Radiation treatment http://purl.obolibrary.org/obo/IEV_0003143 L-Histidine => Histamine + CO2( EC:4.1.1.22 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0003308 S-Adenosyl-L-methionine + H+ => S-Adenosylmethioninamine + CO2( EC:4.1.1.50 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0001068 Decarboxylation in the cytosol http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0002854 GTP + Oxaloacetic acid = GDP + Phosphoenol-pyruvic acid + CO2( EC:4.1.1.32 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0002917 5-Hydroxy-L-tryptophan => Serotonin + CO2( EC:4.1.1.28 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0002963 Malonyl-CoA = Acetyl-CoA + CO2( EC:4.1.1.9 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0002975 5-Hydroxy-kynurenine => 5-Hydroxy-kynurenamine + CO2( EC:4.1.1.28 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0002980 L-Cysteine-sulfinic acid => Hypotaurine + CO2( EC:4.1.1.29 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0003013 L-Tyrosine => Tyramine + CO2( EC:4.1.1.28 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0003043 ATP + (R)-5-Diphosphomevalonate => ADP + Isopentenyl diphosphate + Orthophosphate + CO2( EC:4.1.1.33 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0003061 L-Tryptophan => Tryptamine + CO2( EC:4.1.1.28 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0003082 L-Dopa => Dopamine + CO2( EC:4.1.1.28 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0003090 L-Aspartic acid => beta-Alanine + CO2( EC:4.1.1.15 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0003101 Uroporphyrinogen I => Coproporphyrinogen I + 4 CO2( EC:4.1.1.37 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0003102 L-Ornithine => Putrescine + CO2( EC:4.1.1.17 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0003116 L-Phenylalanine => Phenyl-ethylamine + CO2( EC:4.1.1.28 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0003265 Uroporphyrinogen III => Coproporphyrinogen III + 4 CO2( EC:4.1.1.37 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0003291 L-Glutamic acid => 4-Amino-butanoic acid + CO2( EC:4.1.1.15 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0003303 Phosphatidylserine => Phosphatidyl-ethanolamine + CO2( EC:4.1.1.65 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0003319 L-Cysteic acid => Taurine + CO2( EC:4.1.1.29 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0003320 L-Cysteine-sulfinic acid => Hypotaurine + CO2( EC:4.1.1.15 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0003130 Orotidine 5'-phosphate => UMP + CO2( EC:4.1.1.23 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0001069 Decarboxylation in the unidentified cellular location http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0002944 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate = 5'-Phospho-ribosyl-5-amino-imidazole + CO2( EC:4.1.1.21 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0002914 2-Amino-3-carboxy-muconate semialdehyde => 2-Amino-muconate semialdehyde + CO2( EC:4.1.1.45 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0003109 L-Cysteic acid => Taurine + CO2( EC:4.1.1.15 ) http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0003263 ATP + L-Histidine + tRNA(His) => AMP + L-Histidyl-tRNA(His) + Pyrophosphate( EC:6.1.1.21 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003040 ATP + 5'-Phospho-ribosyl-N-formyl-glycinamidine => ADP + 5'-Phospho-ribosyl-5-amino-imidazole + Orthophosphate( EC:6.3.3.1 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003242 ATP + 7,8-Dihydro-pteroic acid + L-Glutamic acid => ADP + 7,8-Dihydro-folic acid + Orthophosphate( EC:6.3.2.17 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003039 ATP + 3-Methylbut-2-enoyl-CoA + HCO3- => ADP + 3-Methyl-glutaconyl-CoA + Orthophosphate( EC:6.4.1.4 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003293 ATP + 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate + L-Aspartic acid => ADP + 5'-Phospho-ribosyl-4-(N-succino-carboxamide)-5-amino-imidazole + Orthophosphate( EC:6.3.2.6 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003167 ATP + L-Proline + tRNA(Pro) => AMP + L-Prolyl-tRNA(Pro) + Pyrophosphate( EC:6.1.1.15 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003155 ATP + Deamido-NAD+ + L-Glutamine + H2O => AMP + NAD+ + L-Glutamic acid + Pyrophosphate( EC:6.3.5.1 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0000394 CoA ligation http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0002783 ATP + Propanoyl-CoA + HCO3- => ADP + (S)-Methyl-malonyl-CoA + Orthophosphate( EC:6.4.1.3 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0002800 ATP + Pyruvic acid + HCO3- = ADP + Oxaloacetic acid + Orthophosphate( EC:6.4.1.1 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0002898 ATP + XMP + L-Glutamine + H2O => AMP + GMP + L-Glutamic acid + Pyrophosphate( EC:6.3.5.2 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0002943 ATP + L-Tryptophan + tRNA(Trp) => AMP + L-Tryptophanyl-tRNA(Trp) + Pyrophosphate( EC:6.1.1.2 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0002964 GTP + IMP + L-Aspartic acid => GDP + Adenylo-succinic acid + Orthophosphate( EC:6.3.4.4 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003002 ATP + L-Cysteine + tRNA(Cys) => AMP + L-Cysteinyl-tRNA(Cys) + Pyrophosphate( EC:6.1.1.16 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003038 ATP + L-Glutamine + tRNA(Gln) => AMP + Glutaminyl-tRNA + Pyrophosphate( EC:6.1.1.18 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003093 ATP + gamma-L-Glutamyl-L-cysteine + Glycine => ADP + Glutathione + Orthophosphate( EC:6.3.2.3 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003112 ATP + L-Glutamic acid + tRNA(Glu) => AMP + L-Glutamyl-tRNA(Glu) + Pyrophosphate( EC:6.1.1.17 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003151 ATP + L-Threonine + tRNA(Thr) => AMP + L-Threonyl-tRNA(Thr) + Pyrophosphate( EC:6.1.1.3 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003175 ATP + L-Glutamine + L-Aspartic acid + H2O => AMP + L-Glutamic acid + L-Asparagine + Pyrophosphate( EC:6.3.5.4 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003183 ATP + 5'-Phospho-ribosyl-N-formyl-glycinamide + L-Glutamine + H2O => ADP + 5'-Phospho-ribosyl-N-formyl-glycinamidine + L-Glutamic acid + Orthophosphate( EC:6.3.5.3 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003234 ATP + UTP + NH3 => ADP + CTP + Orthophosphate( EC:6.3.4.2 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003237 ATP + L-Aspartic acid + L-Citrulline => AMP + Pyrophosphate + L-Arginino-succinic acid( EC:6.3.4.5 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003240 ATP + Tetrahydrofolate + Formic acid => ADP + 10-Formyl-tetrahydro-folic acid + Orthophosphate( EC:6.3.4.3 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003250 ATP + L-Serine + tRNA(Ser) => AMP + L-Seryl-tRNA(Ser) + Pyrophosphate( EC:6.1.1.11 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003306 ATP + 5-Formyl-tetrahydro-folic acid + H+ => ADP + 5,10-Methenyl-tetrahydro-folic acid + Orthophosphate( EC:6.3.3.2 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003188 ATP + L-Glutamic acid + L-Cysteine => ADP + gamma-L-Glutamyl-L-cysteine + Orthophosphate( EC:6.3.2.2 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003035 ATP + L-Asparagine + tRNA(Asn) => AMP + L-Asparaginyl-tRNA(Asn) + Pyrophosphate( EC:6.1.1.22 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003148 5-Hydroxy-indole-acetic acid => 5-Hydroxy-indole-acetylglycine( EC:6.3.2.- ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003191 ATP + Tetrahydrofolate + L-Glutamic acid => ADP + Tetrahydrofolyl-[Glu] + Orthophosphate( EC:6.3.2.17 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003198 ATP + 5-Phospho-ribosyl-1-amine + Glycine => ADP + 5'-Phospho-ribosyl-glycinamide + Orthophosphate( EC:6.3.4.13 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003139 2 ATP + L-Glutamine + HCO3- + H2O = 2 ADP + L-Glutamic acid + Carbamoyl phosphate + Orthophosphate( EC:6.3.5.5 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003311 ATP + Acetyl-CoA + HCO3- = ADP + Malonyl-CoA + Orthophosphate( EC:6.4.1.2 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0002896 ATP + Glycine + tRNA(Gly) => AMP + Glycyl-tRNA(Gly) + Pyrophosphate( EC:6.1.1.14 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0002913 ATP + L-Alanine + tRNA(Ala) => AMP + L-Alanyl-tRNA(Ala) + Pyrophosphate( EC:6.1.1.7 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0002863 ATP + L-Methionine + tRNA(Met) => AMP + L-Methionyl-tRNA(Met) + Pyrophosphate( EC:6.1.1.10 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0002996 ATP + L-Arginine + tRNA(Arg) => AMP + L-Arginyl-tRNA(Arg) + Pyrophosphate( EC:6.1.1.19 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003225 2 ATP + CO2 + NH3 + H2O => 2 ADP + Carbamoyl phosphate + Orthophosphate( EC:6.3.4.16 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0003298 ATP + L-Aspartic acid + tRNA(Asp) => AMP + L-Aspartyl-tRNA(Asp) + Pyrophosphate( EC:6.1.1.12 ) http://purl.obolibrary.org/obo/IEV_0000912 Ligation http://purl.obolibrary.org/obo/IEV_0000498 Insulin receptor recycling http://purl.obolibrary.org/obo/IEV_0001255 Receptor recycling http://purl.obolibrary.org/obo/IEV_0000910 DR4/5 signaling pathway http://purl.obolibrary.org/obo/IEV_0000465 TNFR signaling pathway http://purl.obolibrary.org/obo/IEV_0002409 TNFR2 signaling pathway http://purl.obolibrary.org/obo/IEV_0000465 TNFR signaling pathway http://purl.obolibrary.org/obo/IEV_0001397 Fas signaling pathway http://purl.obolibrary.org/obo/IEV_0000465 TNFR signaling pathway http://purl.obolibrary.org/obo/IEV_0000911 DR3 signaling pathway http://purl.obolibrary.org/obo/IEV_0000465 TNFR signaling pathway http://purl.obolibrary.org/obo/IEV_0002408 TNFR1 signaling pathway http://purl.obolibrary.org/obo/IEV_0000465 TNFR signaling pathway http://purl.obolibrary.org/obo/IEV_0001241 Changes in polarization state of postsynaptic cell membrane http://purl.obolibrary.org/obo/IEV_0001239 Changes in polarization state of the membrane http://purl.obolibrary.org/obo/IEV_0000743 Changes in polarization state of photoreceptor cell membrane http://purl.obolibrary.org/obo/IEV_0001239 Changes in polarization state of the membrane http://purl.obolibrary.org/obo/IEV_0000266 Phosphorylation of ZAP-70 by Lck_p in cytosol http://purl.obolibrary.org/obo/IEV_0000573 Phosphorylation of ZAP-70 by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000525 Phosphorylation of ZAP-70 by Fyn_p in cytosol http://purl.obolibrary.org/obo/IEV_0000573 Phosphorylation of ZAP-70 by non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0001683 Deacetylation in nucleus http://purl.obolibrary.org/obo/IEV_0001681 Deacetylation http://purl.obolibrary.org/obo/IEV_0001684 Deacetylation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0001681 Deacetylation http://purl.obolibrary.org/obo/IEV_0001682 Deacetylation in cytosol http://purl.obolibrary.org/obo/IEV_0001681 Deacetylation http://purl.obolibrary.org/obo/IEV_0000161 Fas signaling pathway (through caspase cascade) http://purl.obolibrary.org/obo/IEV_0001397 Fas signaling pathway http://purl.obolibrary.org/obo/IEV_0000796 Binding of PPAR and RXR in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000792 Binding of PPAR and nuclear receptor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002546 Accumulation in cytosol http://purl.obolibrary.org/obo/IEV_0002545 Accumulation http://purl.obolibrary.org/obo/IEV_0000436 Isoprenylation in cytosol http://purl.obolibrary.org/obo/IEV_0000921 Isoprenylation http://purl.obolibrary.org/obo/IEV_0000946 Isoprenylation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000921 Isoprenylation http://purl.obolibrary.org/obo/IEV_0002103 Transcription of SOCS by STAT dimer in nucleus http://purl.obolibrary.org/obo/IEV_0000050 Transcription by STAT dimer in nucleus http://purl.obolibrary.org/obo/IEV_0003687 Transcription of vvl by STAT dimer in nucleus http://purl.obolibrary.org/obo/IEV_0000050 Transcription by STAT dimer in nucleus http://purl.obolibrary.org/obo/IEV_0001082 Phosphorylation in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000231 Phosphorylation in nucleus http://purl.obolibrary.org/obo/IEV_0002091 Hydrolysis of GTP by Rap1GAP1 in cytosol http://purl.obolibrary.org/obo/IEV_0002090 Hydrolysis of GTP by RapGAP in cytosol http://purl.obolibrary.org/obo/IEV_0002092 Hydrolysis of GTP by Rap1GAP2 in cytosol http://purl.obolibrary.org/obo/IEV_0002090 Hydrolysis of GTP by RapGAP in cytosol http://purl.obolibrary.org/obo/IEV_0001395 Binding of DAG, calcium ion and cPKC and active conformational change of cPKC in cytosol http://purl.obolibrary.org/obo/IEV_0000484 Binding of DAG, calcium ion and PKC and active conformational change of PKC in cytosol http://purl.obolibrary.org/obo/IEV_0000763 Binding of cGMP and cGMP activated cation ion channel and the channel opening in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000558 Fyn inactivation signaling (through PTP) http://purl.obolibrary.org/obo/IEV_0001888 Negative regulation of (Autophosphorylation of Fyn) in Fyn activation signaling http://purl.obolibrary.org/obo/IEV_0002309 Phosphorylation of PLC gamma2 by Btk in cytosol http://purl.obolibrary.org/obo/IEV_0001290 Phosphorylation of PLC gamma by Btk in cytosol http://purl.obolibrary.org/obo/IEV_0003492 Activation of PSH by GNBP3 in extracellular http://purl.obolibrary.org/obo/IEV_0003491 Activation of serine protease in extracellular http://purl.obolibrary.org/obo/IEV_0000785 Regulation of Toll-like receptor pathway (through LPS, TLR4, MyD88, IRAK-1, TAK1 and IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0001400 Regulation of Toll-like receptor pathway http://purl.obolibrary.org/obo/IEV_0001394 Binding of DAG and cPKC and active conformational change of cPKC in cytosol http://purl.obolibrary.org/obo/IEV_0000270 Binding of DAG and PKC and active conformational change of PKC in cytosol http://purl.obolibrary.org/obo/IEV_0003426 Binding of DAG and nPKC and active conformational change of nPKC in cytosol http://purl.obolibrary.org/obo/IEV_0000270 Binding of DAG and PKC and active conformational change of PKC in cytosol http://purl.obolibrary.org/obo/IEV_0003403 Phosphorylation of transcriptional regulator by JNK_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000479 Phosphorylation of transcriptional regulator by MAPK_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000477 Phosphorylation of transcriptional regulator by ERK_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000479 Phosphorylation of transcriptional regulator by MAPK_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000238 Phosphorylation of transcriptional regulator by p38_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000479 Phosphorylation of transcriptional regulator by MAPK_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000379 Heat treatment http://purl.obolibrary.org/obo/IEV_0000371 Temperature treatment http://purl.obolibrary.org/obo/IEV_0002213 Thermoperiodism http://purl.obolibrary.org/obo/IEV_0000371 Temperature treatment http://purl.obolibrary.org/obo/IEV_0000377 High temperature treatment http://purl.obolibrary.org/obo/IEV_0000371 Temperature treatment http://purl.obolibrary.org/obo/IEV_0000378 Low temperature treatment http://purl.obolibrary.org/obo/IEV_0000371 Temperature treatment http://purl.obolibrary.org/obo/IEV_0003503 Activation of Spaetzle by PSH in extracellular http://purl.obolibrary.org/obo/IEV_0003504 Activation of Spaetzle by serine protease in extracellular http://purl.obolibrary.org/obo/IEV_0002574 Cholesterol modification in ER http://purl.obolibrary.org/obo/IEV_0002573 Cholesterol modification http://purl.obolibrary.org/obo/IEV_0002569 Transcription of HES gene in nucleus http://purl.obolibrary.org/obo/IEV_0001177 Transcription by CSL:Notch (NIC) in nucleus http://purl.obolibrary.org/obo/IEV_0002858 NAD+ + 4-Trimethyl-ammonio-butanal + H2O = NADH + 4-Trimethyl-ammonio-butanoic acid + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0002729 Aldehyde + NAD+ + H2O = Carboxylate + NADH + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0002906 NAD+ + Acetaldehyde + H2O = NADH + Acetic acid + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0002729 Aldehyde + NAD+ + H2O = Carboxylate + NADH + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0002987 NAD+ + 5-Hydroxy-indole-acetaldehyde + H2O => NADH + 5-Hydroxy-indole-acetic acid + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0002729 Aldehyde + NAD+ + H2O = Carboxylate + NADH + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0003114 NAD+ + Indole-3-acetaldehyde + H2O => NADH + Indole-3-acetic acid + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0002729 Aldehyde + NAD+ + H2O = Carboxylate + NADH + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0003302 NAD+ + Imidazole-4-acetaldehyde + H2O = NADH + Imidazole-4-acetic acid + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0002729 Aldehyde + NAD+ + H2O = Carboxylate + NADH + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0002779 NAD+ + N4-Acetylaminobutanal + H2O => NADH + N4-Acetyl-amino-butanoic acid + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0002729 Aldehyde + NAD+ + H2O = Carboxylate + NADH + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0003321 NAD+ + 4-Amino-butyraldehyde + H2O => NADH + 4-Amino-butanoic acid + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0002729 Aldehyde + NAD+ + H2O = Carboxylate + NADH + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0002991 NAD+ + 2-Propyn-1-al + H2O = NADH + Propiolic acid + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0002729 Aldehyde + NAD+ + H2O = Carboxylate + NADH + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0003279 NAD+ + (S)-Methyl-malonate semialdehyde + H2O => NADH + Methyl-malonic acid + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0002729 Aldehyde + NAD+ + H2O = Carboxylate + NADH + H+( EC:1.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0003666 Transcription of MuRF1 in nucleus http://purl.obolibrary.org/obo/IEV_0003661 Transcription of FOXO target gene in nucleus http://purl.obolibrary.org/obo/IEV_0003676 Transcription of 4EBP in nucleus http://purl.obolibrary.org/obo/IEV_0003661 Transcription of FOXO target gene in nucleus http://purl.obolibrary.org/obo/IEV_0003665 Transcription of MAFbx in nucleus http://purl.obolibrary.org/obo/IEV_0003661 Transcription of FOXO target gene in nucleus http://purl.obolibrary.org/obo/IEV_0002121 Dimerization of STAT1 and STAT2 in cytosol http://purl.obolibrary.org/obo/IEV_0000047 Dimerization of STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002122 Dimerization of STAT1 in cytosol http://purl.obolibrary.org/obo/IEV_0000047 Dimerization of STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002123 Dimerization of STAT3 in cytosol http://purl.obolibrary.org/obo/IEV_0000047 Dimerization of STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002124 Dimerization of STAT1 and STAT3 in cytosol http://purl.obolibrary.org/obo/IEV_0000047 Dimerization of STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002125 Dimerization of STAT5 in cytosol http://purl.obolibrary.org/obo/IEV_0000047 Dimerization of STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002298 Dimerization of STAT6 in cytosol http://purl.obolibrary.org/obo/IEV_0000047 Dimerization of STAT in cytosol http://purl.obolibrary.org/obo/IEV_0003603 Dimerization of STAT3 and STAT4 in cytosol http://purl.obolibrary.org/obo/IEV_0000047 Dimerization of STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002126 Dimerization of STAT4 in cytosol http://purl.obolibrary.org/obo/IEV_0000047 Dimerization of STAT in cytosol http://purl.obolibrary.org/obo/IEV_0000032 Complex formation of Axin, APC, GSK3beta, CK1alpha and beta catenin in cytosol http://purl.obolibrary.org/obo/IEV_0001968 Complex formation of Axin, APC, GSK-3, CK1alpha and beta catenin in cytosol http://purl.obolibrary.org/obo/IEV_0000798 Regulation of PPAR signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000544 Regulation of Fas signaling pathway http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000552 Regulation of NF-kappaB signaling (cytoplasmic sequestering) http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000610 Regulation of integrin signaling pathway http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000668 Regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000834 Regulation of RTK signaling pathway http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001407 Regulation of PLC signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001776 Regulation of Steroid receptor signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001799 Regulation of Bad activation signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001909 Regulation of PKC activation signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001925 Regulation of PKA activation signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0002044 Regulation of G alpha GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0003543 Regulation of Ras-Raf-MAPK signaling by spred http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0003678 Regulation of AKT(PKB)-TOR signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001485 Regulation of AKT(PKB) activation signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001867 Regulation of HDAC nuclear export signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001870 Regulation of HDAC nuclear import signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001685 Regulation of caloric restriction - cell survival signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000539 Regulation of Caspase cascade http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0003682 Regulation of G alpha-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000461 Regulation of p53 signaling pathway http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000520 Regulation of Src family activation signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001850 Regulation of AKT(PKB)-Bad signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001122 Regulation of p53 degradation signaling http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000879 Regulation of TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0003681 signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000809 Phosphorylation of MEKK1 by NIK in cytosol http://purl.obolibrary.org/obo/IEV_0000633 Phosphorylation of MAPKKK by MAPKKKK in cytosol http://purl.obolibrary.org/obo/IEV_0000629 Phosphorylation of MAPKKK by PAK in cytosol http://purl.obolibrary.org/obo/IEV_0000633 Phosphorylation of MAPKKK by MAPKKKK in cytosol http://purl.obolibrary.org/obo/IEV_0000081 Epithelial to mesenchymal transdifferentiation http://purl.obolibrary.org/obo/IEV_0000080 Transdifferentiation http://purl.obolibrary.org/obo/IEV_0001588 Actinomycin medication http://purl.obolibrary.org/obo/IEV_0001571 Transcription inhibitor medication http://purl.obolibrary.org/obo/IEV_0001572 DRB medication http://purl.obolibrary.org/obo/IEV_0001571 Transcription inhibitor medication http://purl.obolibrary.org/obo/IEV_0001528 beta-Lactam resistanse http://purl.obolibrary.org/obo/IEV_0001560 Biosynthesis of Secondary Metabolites http://purl.obolibrary.org/obo/IEV_0002558 Binding of Notch and Serrate/Jagged in extracellular http://purl.obolibrary.org/obo/IEV_0001168 Binding of Notch and DSL ligand in extracellular http://purl.obolibrary.org/obo/IEV_0001181 Binding of Notch and Delta in extracellular http://purl.obolibrary.org/obo/IEV_0001168 Binding of Notch and DSL ligand in extracellular http://purl.obolibrary.org/obo/IEV_0000647 Activation of PI5K by Rho in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0000243 Activation of IRAK in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0000257 Activation of MEKK3 by RIP in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0000282 Activation of TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0000608 Activation of Raf by Ras-GTP in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0000619 Activation of MLCK by ERK_p in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0000628 Activation of PAK by Rac in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0000632 Activation of MAPKKKK by Rap1 in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0000646 Activation of ERM by PIP2 in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0000649 Activation of p160ROCK by Rho in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0000660 Activation of PAK by Cdc42 in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0000808 Activation of NIK by RIP in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0000849 Activation of RalGDS by Ras-GTP in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0000978 Activation of Bax by Bid in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0001105 Activation of ATM by damaged DNA in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0001141 Activation of p27 by Contact pressure in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0001151 Activation of p21 by Contact pressure in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0001362 Activation of Raf by PKC in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0002068 Activation of B-Raf by Rap1 in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0002073 Activation of Epac by cAMP in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0002202 Activation of PKC theta by Rac in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0002422 Activation of PP2A by PKA in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0002448 Activation of MEKK1 by Ras-GTP in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0002552 Activation of NLK by TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0002554 Activation of APC in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0002555 Activation of GSK3beta in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0002651 Activation of protein kinase by Pelle in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0003406 Activation of ASK1 by DAXX in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0003541 Activation of Deltex in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0003542 Activation of Numb in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0003636 Activation of TORC1 in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0000256 Activation of RIP by TRAF2 in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0000807 Activation of MEKK1 by RIP in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0002484 Activation of PKC by DAG in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0003859 Activation of NF-kappaB in cytosol http://purl.obolibrary.org/obo/IEV_0000020 Activation in cytosol http://purl.obolibrary.org/obo/IEV_0001978 PI3K activation signaling (through Estrogen receptor) http://purl.obolibrary.org/obo/IEV_0001227 PI3K activation signaling http://purl.obolibrary.org/obo/IEV_0001987 PI3K gamma activation singlaing http://purl.obolibrary.org/obo/IEV_0001227 PI3K activation signaling http://purl.obolibrary.org/obo/IEV_0001979 PI3K activation signaling (through IRS) http://purl.obolibrary.org/obo/IEV_0001227 PI3K activation signaling http://purl.obolibrary.org/obo/IEV_0003869 Phosphorylation of ets domain transcription factor by ERK_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000477 Phosphorylation of transcriptional regulator by ERK_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000769 Depolarization state of photoreceptor cell membrane http://purl.obolibrary.org/obo/IEV_0000743 Changes in polarization state of photoreceptor cell membrane http://purl.obolibrary.org/obo/IEV_0000768 Hyper polarization state of photoreceptor cell membrane http://purl.obolibrary.org/obo/IEV_0000743 Changes in polarization state of photoreceptor cell membrane http://purl.obolibrary.org/obo/IEV_0001496 Glycosphingolipid biosynthesis-neo-lactoseries http://purl.obolibrary.org/obo/IEV_0001494 Sphingolipid metabolism http://purl.obolibrary.org/obo/IEV_0001495 Glycosphingolipid biosynthesis-lactoseries http://purl.obolibrary.org/obo/IEV_0001494 Sphingolipid metabolism http://purl.obolibrary.org/obo/IEV_0002339 TGF beta signaling pathway (through TAK1) http://purl.obolibrary.org/obo/IEV_0000864 TGF beta signaling pathway http://purl.obolibrary.org/obo/IEV_0000073 Bud dormancy http://purl.obolibrary.org/obo/IEV_0000072 Dormancy http://purl.obolibrary.org/obo/IEV_0000365 Cambium dormancy http://purl.obolibrary.org/obo/IEV_0000072 Dormancy http://purl.obolibrary.org/obo/IEV_0002140 Phosphorylation of IFN alpha receptor by JAK1 and TYK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000053 Phosphorylation of cytokine receptor by Jak in cytosol http://purl.obolibrary.org/obo/IEV_0002141 Phosphorylation of IFN gamma receptor by JAK1 and JAK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000053 Phosphorylation of cytokine receptor by Jak in cytosol http://purl.obolibrary.org/obo/IEV_0002142 Phosphorylation of IL-6 receptor by JAK1 and JAK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000053 Phosphorylation of cytokine receptor by Jak in cytosol http://purl.obolibrary.org/obo/IEV_0002144 Phosphorylation of IL-2 receptor by JAK1 and JAK3 in cytosol http://purl.obolibrary.org/obo/IEV_0000053 Phosphorylation of cytokine receptor by Jak in cytosol http://purl.obolibrary.org/obo/IEV_0002145 Phosphorylation of IL-12 receptor by JAK2 and TYK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000053 Phosphorylation of cytokine receptor by Jak in cytosol http://purl.obolibrary.org/obo/IEV_0002156 Phosphorylation of LIF receptor by JAK1 and JAK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000053 Phosphorylation of cytokine receptor by Jak in cytosol http://purl.obolibrary.org/obo/IEV_0002294 Phosphorylation of IL-4 receptor by JAK1 and JAK3 in cytosol http://purl.obolibrary.org/obo/IEV_0000053 Phosphorylation of cytokine receptor by Jak in cytosol http://purl.obolibrary.org/obo/IEV_0002320 Phosphorylation of GH receptor by JAK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000053 Phosphorylation of cytokine receptor by Jak in cytosol http://purl.obolibrary.org/obo/IEV_0002331 Phosphorylation of IL-7 receptor by JAK1 and JAK3 in cytosol http://purl.obolibrary.org/obo/IEV_0000053 Phosphorylation of cytokine receptor by Jak in cytosol http://purl.obolibrary.org/obo/IEV_0003435 Phosphorylation of EPO receptor by JAK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000053 Phosphorylation of cytokine receptor by Jak in cytosol http://purl.obolibrary.org/obo/IEV_0003597 Phosphorylation of IL-23 receptor by JAK2 and TYK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000053 Phosphorylation of cytokine receptor by Jak in cytosol http://purl.obolibrary.org/obo/IEV_0003611 Phosphorylation of IL-4 receptor by JAK1 and TYK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000053 Phosphorylation of cytokine receptor by Jak in cytosol http://purl.obolibrary.org/obo/IEV_0003622 Phosphorylation of IL-5 receptor and JAK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000053 Phosphorylation of cytokine receptor by Jak in cytosol http://purl.obolibrary.org/obo/IEV_0002657 Phosphorylation of TPO receptor by JAK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000053 Phosphorylation of cytokine receptor by Jak in cytosol http://purl.obolibrary.org/obo/IEV_0002327 Phosphorylation of IL-3 receptor by JAK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000053 Phosphorylation of cytokine receptor by Jak in cytosol http://purl.obolibrary.org/obo/IEV_0002143 Phosphorylation of IL-10 receptor by JAK1 and TYK2 in cytosol http://purl.obolibrary.org/obo/IEV_0000053 Phosphorylation of cytokine receptor by Jak in cytosol http://purl.obolibrary.org/obo/IEV_0001579 Ethylene stimulus http://purl.obolibrary.org/obo/IEV_0000294 Plant hormone medication http://purl.obolibrary.org/obo/IEV_0001574 Abscisic acid stimulus http://purl.obolibrary.org/obo/IEV_0000294 Plant hormone medication http://purl.obolibrary.org/obo/IEV_0001575 Auxin stimulus http://purl.obolibrary.org/obo/IEV_0000294 Plant hormone medication http://purl.obolibrary.org/obo/IEV_0001577 Brassinosteroid stimulus http://purl.obolibrary.org/obo/IEV_0000294 Plant hormone medication http://purl.obolibrary.org/obo/IEV_0001578 Cytokinin stimulus http://purl.obolibrary.org/obo/IEV_0000294 Plant hormone medication http://purl.obolibrary.org/obo/IEV_0001580 Gibberellic acid stimulus http://purl.obolibrary.org/obo/IEV_0000294 Plant hormone medication http://purl.obolibrary.org/obo/IEV_0001730 Binding in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0000004 Binding http://purl.obolibrary.org/obo/IEV_0000014 Binding in plasma membrane http://purl.obolibrary.org/obo/IEV_0000004 Binding http://purl.obolibrary.org/obo/IEV_0001184 Binding in Golgi http://purl.obolibrary.org/obo/IEV_0000004 Binding http://purl.obolibrary.org/obo/IEV_0000186 Binding in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000004 Binding http://purl.obolibrary.org/obo/IEV_0000016 Binding in extracellular http://purl.obolibrary.org/obo/IEV_0000004 Binding http://purl.obolibrary.org/obo/IEV_0002524 Clustering http://purl.obolibrary.org/obo/IEV_0000004 Binding http://purl.obolibrary.org/obo/IEV_0001035 Binding in ER http://purl.obolibrary.org/obo/IEV_0000004 Binding http://purl.obolibrary.org/obo/IEV_0001036 Binding in mitochondria http://purl.obolibrary.org/obo/IEV_0000004 Binding http://purl.obolibrary.org/obo/IEV_0001710 Phosphorylation of FOXO3 by AKT in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003659 Phosphorylation of FOXO by AKT in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002777 D-Mannose 6-phosphate = beta-D-Fructose 6-phosphate( EC:5.3.1.8 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0003123 D-Glucose 6-phosphate => D-myo-Inositol 3-phosphate( EC:5.5.1.4 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0003277 UDP-N-acetyl-D-glucosamine => UDP-N-acetyl-D-mannosamine( EC:5.1.3.14 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0001053 Isomerization in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0002808 Prostaglandin H2 = Prostaglandin I2( EC:5.3.99.4 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0002826 Prostaglandin H2 => Prostaglandin E2( EC:5.3.99.3 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0002853 D-Glycerate 2-phosphate = D-Glycerate 3-phosphate( EC:5.4.2.1 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0002857 Prostaglandin H2 => Thromboxane A2( EC:5.3.99.5 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0002937 D-Ribose 1-phosphate = D-Ribose 5-phosphate( EC:5.4.2.2 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0002983 D-Mannose 1-phosphate = D-Mannose 6-phosphate( EC:5.4.2.8 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0003033 UDP-D-glucose = UDP-D-galactose( EC:5.1.3.2 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0003036 D-Glyceraldehyde 3-phosphate = Dihydroxy-acetone phosphate( EC:5.3.1.1 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0003100 (R)-Methyl-malonyl-CoA = Succinyl-CoA( EC:5.4.99.2 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0003106 N-Acetyl-alpha-D-glucosamine 1-phosphate = N-Acetyl-D-glucosamine 6-phosphate( EC:5.4.2.3 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0003229 Prostaglandin H2 => Prostaglandin D2( EC:5.3.99.2 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0003221 (S)-2,3-Epoxy-squalene = Lanosterol( EC:5.4.99.7 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0001052 Isomerization in cytosol http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0002856 (R)-Methyl-malonyl-CoA = (S)-Methyl-malonyl-CoA( EC:5.1.99.1 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0002859 4-Maleyl-acetoacetic acid => 4-Fumaryl-acetoacetic acid( EC:5.2.1.2 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0003171 UDP-N-acetyl-D-glucosamine + H2O => UDP + N-acetyl-D-mannosamine( EC:5.1.3.14 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0002948 D-Glucose 1-phosphate = alpha-D-Glucose 6-phosphate( EC:5.4.2.2 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0002760 N-acyl-D-glucosamine = N-acyl-D-mannosamine( EC:5.1.3.8 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0002932 beta-D-Glucose 6-phosphate = beta-D-Fructose 6-phosphate( EC:5.3.1.9 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0002875 Dimethylallyl diphosphate = Isopentenyl diphosphate( EC:5.3.3.2 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0002855 D-Ribose 5-phosphate = D-Ribulose 5-phosphate( EC:5.3.1.6 ) http://purl.obolibrary.org/obo/IEV_0000915 Isomerization http://purl.obolibrary.org/obo/IEV_0000791 Binding outside the nuclear membrane http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001020 Positive regulation of Caspase cascade http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001021 Regulation of Caspase cascade (not through mitochondria) http://purl.obolibrary.org/obo/IEV_0000539 Regulation of Caspase cascade http://purl.obolibrary.org/obo/IEV_0001019 Negative regulation of Caspase cascade http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001018 Regulation of Caspase cascade (through mitochondria) http://purl.obolibrary.org/obo/IEV_0000539 Regulation of Caspase cascade http://purl.obolibrary.org/obo/IEV_0002813 NAD+ + 3,4-Dihydroxy-phenyl-ethyleneglycol = NADH + 3,4-Dihydroxy-mandelaldehyde + H+( EC:1.1.1.1 ) http://purl.obolibrary.org/obo/IEV_0002722 Alcohol + NAD+ = Aldehyde + NADH + H+( EC:1.1.1.1 ) http://purl.obolibrary.org/obo/IEV_0000476 Phosphorylation of ERK by MEK1/2(MKK1/2)_p in cytosol http://purl.obolibrary.org/obo/IEV_0002067 Phosphorylation of MAPK by MEK in cytosol http://purl.obolibrary.org/obo/IEV_0002016 Binding of G alpha q-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0000666 Binding of G alpha-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0001992 Binding of G alpha s-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0000666 Binding of G alpha-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0001997 Binding of G alpha i-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0000666 Binding of G alpha-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0001998 Binding of G alpha o-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0000666 Binding of G alpha-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0002013 Binding of G alpha t-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0000666 Binding of G alpha-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0002014 Binding of G alpha 11-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0000666 Binding of G alpha-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0003862 Binding of G alpha 12/13-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0000666 Binding of G alpha-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0000674 Binding of G alpha-GTP and RGS in cytosol http://purl.obolibrary.org/obo/IEV_0000666 Binding of G alpha-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0002077 Binding of G alpha z-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0000666 Binding of G alpha-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0000169 Oxidation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000382 Oxidation http://purl.obolibrary.org/obo/IEV_0000171 Oxidation in cytosol http://purl.obolibrary.org/obo/IEV_0000382 Oxidation http://purl.obolibrary.org/obo/IEV_0000857 RalGDS-Ral-PLD1 signaling http://purl.obolibrary.org/obo/IEV_0001263 Ral mediated signaling http://purl.obolibrary.org/obo/IEV_0000826 RalGDS-Ral-RalBP1 signaling http://purl.obolibrary.org/obo/IEV_0001263 Ral mediated signaling http://purl.obolibrary.org/obo/IEV_0000344 MEM (medium) http://purl.obolibrary.org/obo/IEV_0000343 All-purpose medium http://purl.obolibrary.org/obo/IEV_0000199 GDP-GTP exchange in plasma membrane http://purl.obolibrary.org/obo/IEV_0000223 GDP-GTP exchange http://purl.obolibrary.org/obo/IEV_0000605 GDP-GTP exchange in cytosol http://purl.obolibrary.org/obo/IEV_0000223 GDP-GTP exchange http://purl.obolibrary.org/obo/IEV_0000606 GDP-GTP exchange in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000223 GDP-GTP exchange http://purl.obolibrary.org/obo/IEV_0001787 Sumoylation of Androgen receptor by PIAS4 http://purl.obolibrary.org/obo/IEV_0001054 SUMOylation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0001737 Gene expression of beta-TrCP http://purl.obolibrary.org/obo/IEV_0000182 Gene expression http://purl.obolibrary.org/obo/IEV_0000233 Gene expression by transcriptional regulator http://purl.obolibrary.org/obo/IEV_0000182 Gene expression http://purl.obolibrary.org/obo/IEV_0002106 Phosphorylation of p38 by MKK_p in cytosol http://purl.obolibrary.org/obo/IEV_0000478 Phosphorylation of MAPK by MAPKK in cytosol http://purl.obolibrary.org/obo/IEV_0002067 Phosphorylation of MAPK by MEK in cytosol http://purl.obolibrary.org/obo/IEV_0000478 Phosphorylation of MAPK by MAPKK in cytosol http://purl.obolibrary.org/obo/IEV_0001164 Hydrolysis of precursor Notch by convertase in Golgi http://purl.obolibrary.org/obo/IEV_0001165 Hydrolysis in Golgi http://purl.obolibrary.org/obo/IEV_0003609 IL13 signaling pathway (JAK1, TYK2, STAT6) http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000062 JAK STAT signaling (Angiotensin induced) http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000135 IL3 signaling pathway (JAK1, JAK2, STAT5) http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000136 IL2 signaling (JAK1, JAK3, STAT5) http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0002259 IL6 signaling pathway (JAK1, JAK2, STAT3) http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0002260 IFN alpha signaling pathway (JAK1, TYK2, STAT1) http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0002261 IFN alpha signaling pathway (JAK1, TYK2, STAT1, STAT3) http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0002263 IFN alpha signaling pathway (JAK1, TYK2, STAT1, STAT2) http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0002264 IFN gamma signaling pathway (JAK1, JAK2, STAT1) http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0003595 IL23 signaling pathway (JAK2, TYK2, STAT3, STAT4) http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000867 EPO signaling pathway http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000133 Growth hormone signaling pathway (JAK2, STAT5) http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0001233 TPO signaling pathway (JAK2, STAT3) http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0002265 IFN alpha signaling pathway (JAK1, TYK2, STAT3) http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000140 IL7 signaling (JAK1, JAK3, STAT5) http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0003620 IL5 signaling pathway (JAK1, JAK2, STAT1, STAT5) http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000134 IL4 signaling pathway (JAK1, JAK3, STAT6) http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000138 IL12 signaling pathway (JAK2, TYK2, STAT4) http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000139 IL10 signaling (JAK1, TYK2, STAT3) http://purl.obolibrary.org/obo/IEV_0000044 JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000346 Alpha MEM (medium) http://purl.obolibrary.org/obo/IEV_0000333 Hybridoma cell medium http://purl.obolibrary.org/obo/IEV_0000340 IMDM (medium) http://purl.obolibrary.org/obo/IEV_0000322 Lymphocyte medium http://purl.obolibrary.org/obo/IEV_0001859 Regulation of (negative regulation of AKT(PKB) activation signaling) http://purl.obolibrary.org/obo/IEV_0001486 Negative regulation of AKT(PKB) activation signaling http://purl.obolibrary.org/obo/IEV_0001848 Negative regulation of (phosphorylation of AKT(PKB)) in AKT(PKB) activation signaling http://purl.obolibrary.org/obo/IEV_0001486 Negative regulation of AKT(PKB) activation signaling http://purl.obolibrary.org/obo/IEV_0001858 Negative regulation of (phosphorylation of PIP2) in AKT(PKB) activation signaling http://purl.obolibrary.org/obo/IEV_0001486 Negative regulation of AKT(PKB) activation signaling http://purl.obolibrary.org/obo/IEV_0000810 Phosphorylation of IKK complex by MEKK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000250 Phosphorylation of IKK complex by MAPKKK in cytosol http://purl.obolibrary.org/obo/IEV_0000054 Bad inactivation signaling http://purl.obolibrary.org/obo/IEV_0001800 Negative regulation of Bad activation signaling http://purl.obolibrary.org/obo/IEV_0003766 Degradation of Smo in lysosome http://purl.obolibrary.org/obo/IEV_0003765 Degradation in lysosome http://purl.obolibrary.org/obo/IEV_0000657 Positive regulation of Integrin signaling pathway (through Rho) http://purl.obolibrary.org/obo/IEV_0000655 Regulation of Integrin signaling pathway (through Rho) http://purl.obolibrary.org/obo/IEV_0002088 Phosphorylation of MEK1/2(MKK1/2) by B-Raf in cytosol http://purl.obolibrary.org/obo/IEV_0000820 Phosphorylation of MEK1/2(MKK1/2) by Raf in cytosol http://purl.obolibrary.org/obo/IEV_0002449 Phosphorylation of MEK1/2(MKK1/2) by Raf1 in cytosol http://purl.obolibrary.org/obo/IEV_0000820 Phosphorylation of MEK1/2(MKK1/2) by Raf in cytosol http://purl.obolibrary.org/obo/IEV_0003161 S-Adenosyl-L-methionine + Serotonin => S-Adenosyl-L-homocysteine + N-Methyl-serotonin( EC:2.1.1.49 ) http://purl.obolibrary.org/obo/IEV_0002737 S-adenosyl-L-methionine + Amine = S-adenosyl-L-homocysteine + Methylated amine( EC:2.1.1.49 ) http://purl.obolibrary.org/obo/IEV_0003103 S-Adenosyl-L-methionine + Tryptamine => S-Adenosyl-L-homocysteine + N-Methyl-tryptamine( EC:2.1.1.49 ) http://purl.obolibrary.org/obo/IEV_0002737 S-adenosyl-L-methionine + Amine = S-adenosyl-L-homocysteine + Methylated amine( EC:2.1.1.49 ) http://purl.obolibrary.org/obo/IEV_0003425 Phosphorylation of Raf by PKC delta in cytosol http://purl.obolibrary.org/obo/IEV_0002087 Phosphorylation of Raf by PKC in cytosol http://purl.obolibrary.org/obo/IEV_0003427 Phosphorylation of Raf1 by PKC in cytosol http://purl.obolibrary.org/obo/IEV_0002087 Phosphorylation of Raf by PKC in cytosol http://purl.obolibrary.org/obo/IEV_0001568 Ultraviolet irradiation http://purl.obolibrary.org/obo/IEV_0000373 Wavelength of light treatment http://purl.obolibrary.org/obo/IEV_0001051 Hydrolysis in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001026 Hydrolysis in nucleus http://purl.obolibrary.org/obo/IEV_0002311 Binding of BLNK and PLC gamma2 in cytosol http://purl.obolibrary.org/obo/IEV_0001286 Binding of BLNK and PLC gamma in cytosol http://purl.obolibrary.org/obo/IEV_0001427 Butanoate metabolism http://purl.obolibrary.org/obo/IEV_0001422 Carbohydrate Metabolism http://purl.obolibrary.org/obo/IEV_0001428 C5-Branched dibasic acid metabolism http://purl.obolibrary.org/obo/IEV_0001422 Carbohydrate Metabolism http://purl.obolibrary.org/obo/IEV_0001426 Propanoate metabolism http://purl.obolibrary.org/obo/IEV_0001422 Carbohydrate Metabolism http://purl.obolibrary.org/obo/IEV_0001416 Pentose and glucuronate interconversions http://purl.obolibrary.org/obo/IEV_0001422 Carbohydrate Metabolism http://purl.obolibrary.org/obo/IEV_0001190 Positive regulation of Delta mediated Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0001180 Positive regulation of Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0001828 SUMOylation in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0000118 SUMOylation http://purl.obolibrary.org/obo/IEV_0001054 SUMOylation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000118 SUMOylation http://purl.obolibrary.org/obo/IEV_0003733 Negative feedback regulation of EGF receptor signaling by Sprouty http://purl.obolibrary.org/obo/IEV_0001351 Negative regulation of EGF receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0003734 Negative feedback regulation of EGF receptor signaling by Kek http://purl.obolibrary.org/obo/IEV_0001351 Negative regulation of EGF receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0003735 Negative feedback regulation of EGF receptor signaling by Argos http://purl.obolibrary.org/obo/IEV_0001351 Negative regulation of EGF receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0001435 Reductive carboxylate cycle (CO2 fixation) http://purl.obolibrary.org/obo/IEV_0001552 Energy Metabolism http://purl.obolibrary.org/obo/IEV_0001437 Nitrogen metabolism http://purl.obolibrary.org/obo/IEV_0001552 Energy Metabolism http://purl.obolibrary.org/obo/IEV_0001434 Carbon fixation http://purl.obolibrary.org/obo/IEV_0001552 Energy Metabolism http://purl.obolibrary.org/obo/IEV_0000043 Inorganic chemical treatment http://purl.obolibrary.org/obo/IEV_0000028 Chemical treatment http://purl.obolibrary.org/obo/IEV_0000064 Organic chemical treatment http://purl.obolibrary.org/obo/IEV_0000028 Chemical treatment http://purl.obolibrary.org/obo/IEV_0001846 Negative regulation of (nuclear import of R-Smad:Smad4) in TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0000880 Negative regulation of TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0002186 Negative regulation of (transcription by R-Smad:Smad4) in TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0000880 Negative regulation of TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0000885 Negative feedback regulation pathway of TGF beta superfamily signaling http://purl.obolibrary.org/obo/IEV_0000880 Negative regulation of TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0001672 Positive regulation of PDGF signaling pathway http://purl.obolibrary.org/obo/IEV_0001406 Regulation of PDGF signaling pathway http://purl.obolibrary.org/obo/IEV_0002226 Nuclear export of mRNA (SOCS3) http://purl.obolibrary.org/obo/IEV_0002105 Nuclear export of mRNA (SOCS) http://purl.obolibrary.org/obo/IEV_0002239 Nuclear export of mRNA (SOCS1) http://purl.obolibrary.org/obo/IEV_0002105 Nuclear export of mRNA (SOCS) http://purl.obolibrary.org/obo/IEV_0002008 Regulation of G alpha s-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0003682 Regulation of G alpha-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002024 Regulation of G alpha i-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0003682 Regulation of G alpha-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002035 Regulation of G alpha q-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0003682 Regulation of G alpha-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002039 Regulation of G alpha t-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0003682 Regulation of G alpha-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0002957 N-Acetyl-D-glucosamine = N-Acetyl-D-mannosamine( EC:5.1.3.8 ) http://purl.obolibrary.org/obo/IEV_0002760 N-acyl-D-glucosamine = N-acyl-D-mannosamine( EC:5.1.3.8 ) http://purl.obolibrary.org/obo/IEV_0002586 Glycosylation of Dlp/Dally by Tout-velu in cytosol http://purl.obolibrary.org/obo/IEV_0002585 Glycosylation of HSPG by Exostosin in cytosol http://purl.obolibrary.org/obo/IEV_0001244 Long-Term Potentiation http://purl.obolibrary.org/obo/IEV_0000744 Neurological system process http://purl.obolibrary.org/obo/IEV_0001239 Changes in polarization state of the membrane http://purl.obolibrary.org/obo/IEV_0000744 Neurological system process http://purl.obolibrary.org/obo/IEV_0000758 Rhodopsin dark adaptation http://purl.obolibrary.org/obo/IEV_0000744 Neurological system process http://purl.obolibrary.org/obo/IEV_0003887 Translocation of BMP to the dorsal midline http://purl.obolibrary.org/obo/IEV_0003888 Translocation in extracellular http://purl.obolibrary.org/obo/IEV_0003037 Lactose + H2O => alpha-D-Glucose + D-Galactose( EC:3.2.1.23 ) http://purl.obolibrary.org/obo/IEV_0002753 Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides( EC:3.2.1.23 ) http://purl.obolibrary.org/obo/IEV_0003122 Galactan + H2O => 2 D-Galactose( EC:3.2.1.23 ) http://purl.obolibrary.org/obo/IEV_0002753 Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides( EC:3.2.1.23 ) http://purl.obolibrary.org/obo/IEV_0002204 Phosphorylation of JNK by MKK4(SEK1)_p in cytosol http://purl.obolibrary.org/obo/IEV_0000228 Phosphorylation of JNK by MKK4/7_p in cytosol http://purl.obolibrary.org/obo/IEV_0000695 Positive regulation of heterotrimeric GPCR signaling pathway (through G alpha i) http://purl.obolibrary.org/obo/IEV_0000730 Regulation of heterotrimeric GPCR signaling pathway (through G alpha i) http://purl.obolibrary.org/obo/IEV_0000696 Positive regulation of heterotrimeric GPCR signaling pathway (through G alpha s) http://purl.obolibrary.org/obo/IEV_0000731 Regulation of heterotrimeric GPCR signaling pathway (through G alpha s) http://purl.obolibrary.org/obo/IEV_0000753 Positive regulation of heterotrimeric GPCR signaling pathway (through G alpha q and PLC beta) http://purl.obolibrary.org/obo/IEV_0000751 Regulation of heterotrimeric GPCR signaling pathway (through G alpha q and PLC beta) http://purl.obolibrary.org/obo/IEV_0002025 Positive regulation of heteromeric GPCR signaling pathway (through G alpha i and pertussis toxin) http://purl.obolibrary.org/obo/IEV_0000670 Positive regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0002962 2 Acetyl-CoA = CoA + Acetoacetyl-CoA( EC:2.3.1.9 ) http://purl.obolibrary.org/obo/IEV_0002399 Transacetylation http://purl.obolibrary.org/obo/IEV_0003315 Acetyl-CoA + 2-arylethylamine = CoA + N-acetyl-2-arylethylamine( EC:2.3.1.87 ) http://purl.obolibrary.org/obo/IEV_0002399 Transacetylation http://purl.obolibrary.org/obo/IEV_0002823 Acetyl-CoA + Glycine = CoA + L-2-Amino-3-oxo-butanoic acid( EC:2.3.1.29 ) http://purl.obolibrary.org/obo/IEV_0002399 Transacetylation http://purl.obolibrary.org/obo/IEV_0002787 Acetyl-CoA + Enzyme N6-(dihydrolipoyl)lysine = CoA + S-acetyldihydrolipoyllysine( EC:2.3.1.12 ) http://purl.obolibrary.org/obo/IEV_0002399 Transacetylation http://purl.obolibrary.org/obo/IEV_0003077 Acetyl-CoA + D-Glucosamine 6-phosphate => CoA + N-Acetyl-D-glucosamine 6-phosphate( EC:2.3.1.4 ) http://purl.obolibrary.org/obo/IEV_0002399 Transacetylation http://purl.obolibrary.org/obo/IEV_0003314 Acetyl-CoA + alkane-alpha,omega-diamine = CoA + N-acetyldiamine( EC:2.3.1.57 ) http://purl.obolibrary.org/obo/IEV_0002399 Transacetylation http://purl.obolibrary.org/obo/IEV_0002172 Binding of BMP2 and BMP receptor I/II in extracellular http://purl.obolibrary.org/obo/IEV_0003573 Binding of BMP and BMP receptor I/II in extracellular http://purl.obolibrary.org/obo/IEV_0003518 Transcription of antimicrobial peptide in nucleus http://purl.obolibrary.org/obo/IEV_0001308 Transcription by NF-kappaB in nucleus http://purl.obolibrary.org/obo/IEV_0003296 Carnosine + H2O => L-Histidine + beta-Alanine( EC:3.4.13.20 ) http://purl.obolibrary.org/obo/IEV_0002761 Preferential hydrolysis of the beta-Ala-|-His dipeptide (carnosine), and also anserine, Xaa-|-His dipeptides and other dipeptides including homocarnosine( EC:3.4.13.20 ) http://purl.obolibrary.org/obo/IEV_0000693 Negative regulation of heterotrimeric GPCR signaling pathway (through G alpha s) http://purl.obolibrary.org/obo/IEV_0000669 Negative regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0002602 Cleavage of Ci/Gli in cytosol http://purl.obolibrary.org/obo/IEV_0002601 Cleavage in cytosol http://purl.obolibrary.org/obo/IEV_0003386 Processing of MEKK1 in cytosol http://purl.obolibrary.org/obo/IEV_0002601 Cleavage in cytosol http://purl.obolibrary.org/obo/IEV_0001481 Phosphorylation of CD28 by Lck in cytosol http://purl.obolibrary.org/obo/IEV_0001480 Phosphorylation of CD28 by Src family in cytosol http://purl.obolibrary.org/obo/IEV_0001482 Phosphorylation of CD28 by Fyn in cytosol http://purl.obolibrary.org/obo/IEV_0001480 Phosphorylation of CD28 by Src family in cytosol http://purl.obolibrary.org/obo/IEV_0000928 Binding of FADD and pro-caspase10 in cytosol http://purl.obolibrary.org/obo/IEV_0000926 Binding of FADD and pro-caspase8/10 in cytosol http://purl.obolibrary.org/obo/IEV_0000927 Binding of FADD and pro-caspase8 in cytosol http://purl.obolibrary.org/obo/IEV_0000926 Binding of FADD and pro-caspase8/10 in cytosol http://purl.obolibrary.org/obo/IEV_0000463 Negative regulation of p53 signaling pathway http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000464 Positive regulation of p53 signaling pathway http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000094 Membrane ruffling http://purl.obolibrary.org/obo/IEV_0001325 Cell morphogenesis http://purl.obolibrary.org/obo/IEV_0001163 Nuclear export of mRNA (p27) http://purl.obolibrary.org/obo/IEV_0003864 Nuclear export of mRNA (Cip/Kip family) http://purl.obolibrary.org/obo/IEV_0001125 Nuclear export of mRNA (p21) http://purl.obolibrary.org/obo/IEV_0003864 Nuclear export of mRNA (Cip/Kip family) http://purl.obolibrary.org/obo/IEV_0001339 Wood development http://purl.obolibrary.org/obo/IEV_0000398 Post embryonic development http://purl.obolibrary.org/obo/IEV_0001340 Bud development http://purl.obolibrary.org/obo/IEV_0000398 Post embryonic development http://purl.obolibrary.org/obo/IEV_0000405 Translocation of Bad_p from mitochondria membrane to cytosol http://purl.obolibrary.org/obo/IEV_0000175 Translocation from mitochondria membrane to cytosol http://purl.obolibrary.org/obo/IEV_0001692 Translocation of Bax from mitochondria membrane to cytosol http://purl.obolibrary.org/obo/IEV_0000175 Translocation from mitochondria membrane to cytosol http://purl.obolibrary.org/obo/IEV_0001477 O-Glycan biosynthesis http://purl.obolibrary.org/obo/IEV_0001558 Glycan Biosynthesis and Metabolism http://purl.obolibrary.org/obo/IEV_0001474 N-Glycan biosynthesis http://purl.obolibrary.org/obo/IEV_0001558 Glycan Biosynthesis and Metabolism http://purl.obolibrary.org/obo/IEV_0001475 High-mannose type N-glycan biosynthesis http://purl.obolibrary.org/obo/IEV_0001558 Glycan Biosynthesis and Metabolism http://purl.obolibrary.org/obo/IEV_0001476 N-Glycan degradation http://purl.obolibrary.org/obo/IEV_0001558 Glycan Biosynthesis and Metabolism http://purl.obolibrary.org/obo/IEV_0001878 Heparan sulfate biosynthesis http://purl.obolibrary.org/obo/IEV_0001558 Glycan Biosynthesis and Metabolism http://purl.obolibrary.org/obo/IEV_0002775 Propanoyl-CoA + Electron-transferring flavoprotein = Propenoyl-CoA + Reduced electron-transferring flavoprotein( EC:1.3.99.3 ) http://purl.obolibrary.org/obo/IEV_0002732 Acyl-CoA + Acceptor = 2,3-dehydroacyl-CoA + Reduced acceptor( EC:1.3.99.3 ) http://purl.obolibrary.org/obo/IEV_0002912 (S)-2-Methylbutanoyl-CoA + Acceptor = 2-Methylbut-2-enoyl-CoA + Reduced acceptor( EC:1.3.99.3 ) http://purl.obolibrary.org/obo/IEV_0002732 Acyl-CoA + Acceptor = 2,3-dehydroacyl-CoA + Reduced acceptor( EC:1.3.99.3 ) http://purl.obolibrary.org/obo/IEV_0002833 3-Methyl-butanoyl-CoA + FAD = 3-Methylbut-2-enoyl-CoA + FADH2( EC:1.3.99.3 ) http://purl.obolibrary.org/obo/IEV_0002732 Acyl-CoA + Acceptor = 2,3-dehydroacyl-CoA + Reduced acceptor( EC:1.3.99.3 ) http://purl.obolibrary.org/obo/IEV_0002884 2-Methyl-propanoyl-CoA + Acceptor = 2-Methylprop-2-enoyl-CoA + Reduced acceptor( EC:1.3.99.3 ) http://purl.obolibrary.org/obo/IEV_0002732 Acyl-CoA + Acceptor = 2,3-dehydroacyl-CoA + Reduced acceptor( EC:1.3.99.3 ) http://purl.obolibrary.org/obo/IEV_0000698 Hydrolysis of GTP by G alpha i-GTP and RGS in cytosol http://purl.obolibrary.org/obo/IEV_0000672 Hydrolysis of GTP by G alpha-GTP in cytosol http://purl.obolibrary.org/obo/IEV_0000757 Hydrolysis of GTP by G alpha q-GTP and RGS in cytosol http://purl.obolibrary.org/obo/IEV_0000672 Hydrolysis of GTP by G alpha-GTP in cytosol http://purl.obolibrary.org/obo/IEV_0000738 Hydrolysis of GTP by G alpha t-GTP and RGS in cytosol http://purl.obolibrary.org/obo/IEV_0000672 Hydrolysis of GTP by G alpha-GTP in cytosol http://purl.obolibrary.org/obo/IEV_0000700 Hydrolysis of GTP by G alpha s-GTP and RGS in cytosol http://purl.obolibrary.org/obo/IEV_0000672 Hydrolysis of GTP by G alpha-GTP in cytosol http://purl.obolibrary.org/obo/IEV_0001733 Phosphorylation of HDAC5 by CaMK in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001082 Phosphorylation in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000952 Transcription of NOXA by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0001661 Transcription of apoptotic factor by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0000957 Transcription of PUMA by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0001661 Transcription of apoptotic factor by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0001658 Transcription of BAK by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0001661 Transcription of apoptotic factor by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0001659 Transcription of Bid by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0001661 Transcription of apoptotic factor by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0001129 Transcription of BAX by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0001661 Transcription of apoptotic factor by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0001745 AKT(PKB)-GSK3beta signaling http://purl.obolibrary.org/obo/IEV_0001699 AKT signaling http://purl.obolibrary.org/obo/IEV_0000031 Inactivation of GSK3beta by DSH_p in cytosol http://purl.obolibrary.org/obo/IEV_0000024 Inactivation in cytosol http://purl.obolibrary.org/obo/IEV_0000859 Hydrolysis of phosphatidic acid by PLD1 in cytosol http://purl.obolibrary.org/obo/IEV_0000685 Hydrolysis in cytosol http://purl.obolibrary.org/obo/IEV_0000680 Hydrolysis of GTP by small GTPase in cytosol http://purl.obolibrary.org/obo/IEV_0000685 Hydrolysis in cytosol http://purl.obolibrary.org/obo/IEV_0000931 Hydrolysis of pro-caspase8 in cytosol http://purl.obolibrary.org/obo/IEV_0000685 Hydrolysis in cytosol http://purl.obolibrary.org/obo/IEV_0000991 Hydrolysis of Procaspase9 to Caspase9 in cytosol http://purl.obolibrary.org/obo/IEV_0000685 Hydrolysis in cytosol http://purl.obolibrary.org/obo/IEV_0000992 Hydrolysis of Caspase3/6/7 by Caspase9 in cytosol http://purl.obolibrary.org/obo/IEV_0000685 Hydrolysis in cytosol http://purl.obolibrary.org/obo/IEV_0001014 Hydrolysis of Procaspase3/6/7 by caspase8/10 in cytosol http://purl.obolibrary.org/obo/IEV_0000685 Hydrolysis in cytosol http://purl.obolibrary.org/obo/IEV_0003828 Hydrolysis of GTP by small GTPase and GAP in cytosol http://purl.obolibrary.org/obo/IEV_0000685 Hydrolysis in cytosol http://purl.obolibrary.org/obo/IEV_0003829 Hydrolysis of GTP by trimeric G-protein in cytosol http://purl.obolibrary.org/obo/IEV_0000685 Hydrolysis in cytosol http://purl.obolibrary.org/obo/IEV_0000943 Hydrolysis of Bid by granzyme B in cytosol http://purl.obolibrary.org/obo/IEV_0000685 Hydrolysis in cytosol http://purl.obolibrary.org/obo/IEV_0001009 Hydrolysis of pro-caspase10 in cytosol http://purl.obolibrary.org/obo/IEV_0000685 Hydrolysis in cytosol http://purl.obolibrary.org/obo/IEV_0000942 Hydrolysis of Bid by caspase8 in cytosol http://purl.obolibrary.org/obo/IEV_0000685 Hydrolysis in cytosol http://purl.obolibrary.org/obo/IEV_0000472 Hydrolysis of PIP2 by PLC to generate DAG and IP3 in cytosol http://purl.obolibrary.org/obo/IEV_0000685 Hydrolysis in cytosol http://purl.obolibrary.org/obo/IEV_0001029 Hydrolysis of cytosolic protein by caspase3/6/7 in cytosol http://purl.obolibrary.org/obo/IEV_0000685 Hydrolysis in cytosol http://purl.obolibrary.org/obo/IEV_0001015 Hydrolysis of ICAD by Caspase3/7 in cytosol http://purl.obolibrary.org/obo/IEV_0000685 Hydrolysis in cytosol http://purl.obolibrary.org/obo/IEV_0000729 Hydrolysis of cGMP to GMP by cGMP PDE in cytosol http://purl.obolibrary.org/obo/IEV_0000685 Hydrolysis in cytosol http://purl.obolibrary.org/obo/IEV_0001166 Translocation of Notch from the Golgi to plasma membrane http://purl.obolibrary.org/obo/IEV_0001167 Translocation from Golgi to plasma membrane http://purl.obolibrary.org/obo/IEV_0002583 Translocation of HSPG from Golgi to plasma membrane http://purl.obolibrary.org/obo/IEV_0001167 Translocation from Golgi to plasma membrane http://purl.obolibrary.org/obo/IEV_0002617 Translocation of Arrow/LRP5/6 from Golgi to plasma membrane http://purl.obolibrary.org/obo/IEV_0001167 Translocation from Golgi to plasma membrane http://purl.obolibrary.org/obo/IEV_0003292 dCMP + H2O => Deoxy-cytidine + Orthophosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0002751 5'-ribonucleotide + H2O = ribonucleoside + phosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0003150 UMP + H2O => Uridine + Orthophosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0002751 5'-ribonucleotide + H2O = ribonucleoside + phosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0002780 dGMP + H2O => Deoxy-guanosine + Orthophosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0002751 5'-ribonucleotide + H2O = ribonucleoside + phosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0002904 CMP + H2O => Cytidine + Orthophosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0002751 5'-ribonucleotide + H2O = ribonucleoside + phosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0003092 Nicotinate D-ribonucleotide + H2O => Nicotinate D-ribonucleoside + Orthophosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0002751 5'-ribonucleotide + H2O = ribonucleoside + phosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0003134 XMP + H2O => Xanthosine + Orthophosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0002751 5'-ribonucleotide + H2O = ribonucleoside + phosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0003157 AMP + H2O => Adenosine + Orthophosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0002751 5'-ribonucleotide + H2O = ribonucleoside + phosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0003200 dTMP + H2O => Thymidine + Orthophosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0002751 5'-ribonucleotide + H2O = ribonucleoside + phosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0003272 dAMP + H2O => Deoxy-adenosine + Orthophosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0002751 5'-ribonucleotide + H2O = ribonucleoside + phosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0003304 IMP + H2O => Inosine + Orthophosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0002751 5'-ribonucleotide + H2O = ribonucleoside + phosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0002886 Nicotinamide D-ribonucleotide + H2O => N-Ribosyl-nicotinamide + Orthophosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0002751 5'-ribonucleotide + H2O = ribonucleoside + phosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0003031 GMP + H2O => Guanosine + Orthophosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0002751 5'-ribonucleotide + H2O = ribonucleoside + phosphate( EC:3.1.3.5 ) http://purl.obolibrary.org/obo/IEV_0001172 Binding of Notch (NIC) and CSL in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001174 Binding of Notch (NIC) and transcription factor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001173 Binding of Notch (NIC) and coactivator in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001174 Binding of Notch (NIC) and transcription factor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001746 Regulation of EPO signaling pathway http://purl.obolibrary.org/obo/IEV_0000550 Regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0001749 Regulation of Growth hormone signaling pathway (JAK2 STAT5) http://purl.obolibrary.org/obo/IEV_0000550 Regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0001752 Regulation of JAK STAT signaling (Angiotensin induced) http://purl.obolibrary.org/obo/IEV_0000550 Regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0001755 Regulation of TPO signaling pathway (through JAK STAT pathway) http://purl.obolibrary.org/obo/IEV_0000550 Regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0003612 Regulation of IL13 signaling pathway (JAK1, TYK2, STAT6) http://purl.obolibrary.org/obo/IEV_0000550 Regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0003522 Phosphorylation of Cactus in cytosol http://purl.obolibrary.org/obo/IEV_0000213 Phosphorylation of I-kappaB_p by IKK complex_p in cytosol http://purl.obolibrary.org/obo/IEV_0000871 Ubiquitination in nucleus http://purl.obolibrary.org/obo/IEV_0000012 Ubiquitination http://purl.obolibrary.org/obo/IEV_0000204 Ubiquitination in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000012 Ubiquitination http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0000012 Ubiquitination http://purl.obolibrary.org/obo/IEV_0002525 Clustering in plasma membrane http://purl.obolibrary.org/obo/IEV_0002524 Clustering http://purl.obolibrary.org/obo/IEV_0003046 S-Adenosyl-L-methionine + 5-Hydroxy-indole-acetic acid => S-Adenosyl-L-homocysteine + 5-Methoxy-indole-acetic acid( EC:2.1.1.4 ) http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0000435 Transmethylation in cytosol http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0002782 S-Adenosyl-L-methionine + L-Adrenaline => S-Adenosyl-L-homocysteine + L-Metanephrine( EC:2.1.1.6 ) http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0002805 S-Adenosyl-L-methionine + 3,4-Dihydroxy-phenyl-acetic acid => S-Adenosyl-L-homocysteine + Homovanillic acid( EC:2.1.1.6 ) http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0002885 dUMP + 5,10-Methylene-tetrahydro-folic acid => dTMP + 7,8-Dihydro-folic acid( EC:2.1.1.45 ) http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0002921 S-Adenosyl-L-methionine + 3,4-Dihydroxy-mandelic acid => S-Adenosyl-L-homocysteine + 3-Methoxy-4-hydroxy-mandelic acid( EC:2.1.1.6 ) http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0002930 L-Homocysteine + Betaine => L-Methionine + N,N-Dimethyl-glycine( EC:2.1.1.5 ) http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0002974 S-Adenosyl-L-methionine + Guanidino-acetic acid => S-Adenosyl-L-homocysteine + Creatine( EC:2.1.1.2 ) http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0003020 S-Adenosyl-L-methionine + L-Noradrenaline => S-Adenosyl-L-homocysteine + L-Adrenaline( EC:2.1.1.28 ) http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0003252 S-Adenosyl-L-methionine + L-Noradrenaline => S-Adenosyl-L-homocysteine + L-Normetanephrine( EC:2.1.1.6 ) http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0003254 S-Adenosyl-L-methionine + Dopamine => S-Adenosyl-L-homocysteine + 3-Methoxy-tyramine( EC:2.1.1.6 ) http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0003269 S-Adenosyl-L-methionine + Glycine => S-Adenosyl-L-homocysteine + Sarcosine( EC:2.1.1.20 ) http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0003309 S-Adenosyl-L-methionine + Nicotinamide + H+ => S-Adenosyl-L-homocysteine + 1-Methyl-nicotinamide( EC:2.1.1.1 ) http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0000434 Transmethylation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0002737 S-adenosyl-L-methionine + Amine = S-adenosyl-L-homocysteine + Methylated amine( EC:2.1.1.49 ) http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0003129 S-Adenosyl-L-methionine + Phosphatidyl-ethanolamine => S-Adenosyl-L-homocysteine + Phosphatidyl-N-methyl-ethanolamine( EC:2.1.1.17 ) http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0003044 S-Adenosyl-L-methionine + Histamine => S-Adenosyl-L-homocysteine + N-Methyl-histamine( EC:2.1.1.8 ) http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0002862 5-Methyl-tetrahydro-folic acid + L-Homocysteine => Tetrahydrofolate + L-Methionine( EC:2.1.1.13 ) http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0003141 S-Adenosyl-L-methionine + N-Acetyl-serotonin => S-Adenosyl-L-homocysteine + Melatonin( EC:2.1.1.4 ) http://purl.obolibrary.org/obo/IEV_0000433 Transmethylation http://purl.obolibrary.org/obo/IEV_0001378 Phosphorylation of IKK beta by TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000784 Phosphorylation of IKK complex by TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0001365 Binding of PLC gamma1 and PIP3 in cytosol http://purl.obolibrary.org/obo/IEV_0000469 Binding of PLC gamma and PIP3 in cytosol http://purl.obolibrary.org/obo/IEV_0002315 Binding of PLC gamma2 and PIP3 in cytosol http://purl.obolibrary.org/obo/IEV_0000469 Binding of PLC gamma and PIP3 in cytosol http://purl.obolibrary.org/obo/IEV_0001613 Regulation of Fyn activation signaling http://purl.obolibrary.org/obo/IEV_0000520 Regulation of Src family activation signaling http://purl.obolibrary.org/obo/IEV_0001616 Regulation of Lck activation signaling http://purl.obolibrary.org/obo/IEV_0000520 Regulation of Src family activation signaling http://purl.obolibrary.org/obo/IEV_0001619 Regulation of Src activation signaling http://purl.obolibrary.org/obo/IEV_0000520 Regulation of Src family activation signaling http://purl.obolibrary.org/obo/IEV_0001622 Regulation of Src family activation signaling (autophosphorylation and PTP) http://purl.obolibrary.org/obo/IEV_0000520 Regulation of Src family activation signaling http://purl.obolibrary.org/obo/IEV_0000559 Negative regulation of Src family activation signaling http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000560 Positive regulation of Src family activation signaling http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0000752 Negative regulation of heterotrimeric GPCR signaling pathway (through G alpha q and PLC beta) http://purl.obolibrary.org/obo/IEV_0000669 Negative regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0000225 Gene expression of cytokine by AP-1 http://purl.obolibrary.org/obo/IEV_0003387 Gene expression by AP-1 http://purl.obolibrary.org/obo/IEV_0000984 Permeabilization of mitochondria and Translocation of cytochrome c/SMAC from mitochondria to cytosol http://purl.obolibrary.org/obo/IEV_0000985 Translocation from mitochondria to cytosol http://purl.obolibrary.org/obo/IEV_0001666 Permeabilization of mitochondria and Translocation of OMI from mitochondria to cytosol http://purl.obolibrary.org/obo/IEV_0000985 Translocation from mitochondria to cytosol http://purl.obolibrary.org/obo/IEV_0001326 Permeabilization of mitochondria and Translocation of AIF from mitochondria to cytosol http://purl.obolibrary.org/obo/IEV_0000985 Translocation from mitochondria to cytosol http://purl.obolibrary.org/obo/IEV_0000175 Translocation from mitochondria membrane to cytosol http://purl.obolibrary.org/obo/IEV_0000985 Translocation from mitochondria to cytosol http://purl.obolibrary.org/obo/IEV_0001649 Permeabilization of mitochondria and Translocation of EndoG from mitochondria to cytosol http://purl.obolibrary.org/obo/IEV_0000985 Translocation from mitochondria to cytosol http://purl.obolibrary.org/obo/IEV_0000008 Activation http://purl.obolibrary.org/obo/IEV_0001886 Molecular interaction http://purl.obolibrary.org/obo/IEV_0000007 Inactivation http://purl.obolibrary.org/obo/IEV_0001886 Molecular interaction http://purl.obolibrary.org/obo/IEV_0000221 Metabolic reaction http://purl.obolibrary.org/obo/IEV_0001886 Molecular interaction http://purl.obolibrary.org/obo/IEV_0000004 Binding http://purl.obolibrary.org/obo/IEV_0001886 Molecular interaction http://purl.obolibrary.org/obo/IEV_0000006 Dissociation http://purl.obolibrary.org/obo/IEV_0001886 Molecular interaction http://purl.obolibrary.org/obo/IEV_0003156 ATP + Pyridoxine => ADP + Pyridoxine 5'-phosphate( EC:2.7.1.35 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003007 GTP + L-Fucose 1-phosphate = GDP-L-fucose + Pyrophosphate( EC:2.7.7.30 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003113 GDP + Phosphoenol-pyruvic acid => GTP + Pyruvic acid( EC:2.7.1.40 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002745 ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate( EC:2.7.1.60 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003202 ATP + 1-Phosphatidyl-1D-myo-inositol => ADP + 1-Phosphatidyl-1D-myo-inositol 3-phosphate( EC:2.7.1.137 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0000198 Phosphorylation in plasma membrane http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002744 ATP + D-hexose = ADP + D-hexose 6-phosphate( EC:2.7.1.1 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002746 Nucleoside triphosphate + deoxycytidine = Nucleoside diphosphate + dCMP( EC:2.7.1.74 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002748 CTP + N-acylneuraminate = Pyrophosphate + CMP-N-acylneuraminate( EC:2.7.7.43 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002765 ATP + D-Ribose 5-phosphate = AMP + 5-Phospho-alpha-D-ribose 1-diphosphate( EC:2.7.6.1 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002769 ATP + D-Ribose => ADP + D-Ribose 5-phosphate( EC:2.7.1.15 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002781 ATP + 1-Phosphatidyl-1D-myo-inositol 4,5-bisphosphate => ADP + 1-Phosphatidyl-1D-myo-inositol 3,4,5-triphosphate( EC:2.7.1.153 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002789 ATP + 1-Phosphatidyl-1D-myo-inositol => ADP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate( EC:2.7.1.67 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002794 ATP + 1D-myo-inositol 1,4,5-trisphosphate => ADP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate( EC:2.7.1.151 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002806 ATP + D-Glycerate 3-phosphate = ADP + 1,3-Bisphospho-D-glyceric acid( EC:2.7.2.3 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002825 ADP + Phosphoenol-pyruvic acid => ATP + Pyruvic acid( EC:2.7.1.40 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002840 UDP-D-glucose + alpha-D-Galactose 1-phosphate = D-Glucose 1-phosphate + UDP-D-galactose( EC:2.7.7.12 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002845 ATP + dTMP = ADP + dTDP( EC:2.7.4.9 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002883 ATP + 2-Deoxy-D-ribose => ADP + 2-Deoxy-D-ribose 5-phosphate( EC:2.7.1.15 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002889 ATP + dAMP = ADP + dADP( EC:2.7.4.3 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002907 ATP + Nucleoside diphosphate = ADP + Nucleoside triphosphate( EC:2.7.4.6 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002940 ATP + dCMP = ADP + dCDP( EC:2.7.4.14 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002960 ATP + Sulfuric acid => Adenosine-5'-phospho-sulfate + Pyrophosphate( EC:2.7.7.4 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002961 UTP + N-Acetyl-alpha-D-glucosamine 1-phosphate = Pyrophosphate + UDP-N-acetyl-D-glucosamine( EC:2.7.7.23 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002966 ATP + dUMP = ADP + dUDP( EC:2.7.4.9 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002972 ATP + L-Fucose = ADP + L-Fucose 1-phosphate( EC:2.7.1.52 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002984 Nicotinate D-ribonucleotide + ATP = Deamido-NAD+ + Pyrophosphate( EC:2.7.7.1 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003008 ATP + AMP = 2 ADP( EC:2.7.4.3 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003017 ATP + 1-Phosphatidyl-1D-myo-inositol 5-phosphate => ADP + 1-Phosphatidyl-1D-myo-inositol 4,5-bisphosphate( EC:2.7.1.149 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003026 ATP + Deoxy-uridine => ADP + dUMP( EC:2.7.1.21 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003065 ATP + (R)-Mevalonic acid 5-phosphate => ADP + (R)-5-Diphosphomevalonate( EC:2.7.4.2 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003110 ATP + beta-D-Fructose 6-phosphate => ADP + beta-D-Fructose 1,6-bisphosphate( EC:2.7.1.11 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003117 ATP + CMP = ADP + CDP( EC:2.7.4.14 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003118 ATP + D-Galactose => ADP + alpha-D-Galactose 1-phosphate( EC:2.7.1.6 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003203 ATP + Pyridoxal => ADP + Pyridoxal 5'-phosphate( EC:2.7.1.35 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003210 ATP + Adenosine-5'-phospho-sulfate => ADP + 3'-Phospho-adenosine-5'-phospho-sulfate( EC:2.7.1.25 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003227 ATP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate => ADP + 1-Phosphatidyl-1D-myo-inositol 4,5-bisphosphate( EC:2.7.1.68 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003232 dGDP + Phosphoenol-pyruvic acid => dGTP + Pyruvic acid( EC:2.7.1.40 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003244 ATP + Pyridoxamine => ADP + Pyridoxamine 5'-phosphate( EC:2.7.1.35 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003266 ATP + N-Acetyl-D-glucosamine => ADP + N-Acetyl-D-glucosamine 6-phosphate( EC:2.7.1.59 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003297 ATP + 1D-myo-Inositol 1,4,5-trisphosphate => ADP + 1D-myo-Inositol 1,3,4,5-tetrakisphosphate( EC:2.7.1.127 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003299 ATP + Thymidine => ADP + dTMP( EC:2.7.1.21 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002867 ATP + dGMP = ADP + dGDP( EC:2.7.4.8 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002879 ATP + UMP = ADP + UDP( EC:2.7.4.14 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002811 Nicotinamide D-ribonucleotide + ATP = NAD+ + Pyrophosphate( EC:2.7.7.1 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002747 Nucleoside triphosphate + AMP = Nucleoside diphosphate + ADP( EC:2.7.4.10 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003168 ATP + Adenosine => ADP + AMP( EC:2.7.1.20 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0000187 Phosphorylation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003142 ATP + beta-D-Fructose 6-phosphate => ADP + D-Fructose 2,6-bisphosphate( EC:2.7.1.105 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002764 ATP + Uridine => ADP + UMP( EC:2.7.1.48 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002831 ATP + NAD+ => ADP + NADP+( EC:2.7.1.23 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003050 ATP + Creatine = ADP + N-Phospho-creatine( EC:2.7.3.2 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003029 ATP + Cytidine => ADP + CMP( EC:2.7.1.48 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0001735 Phosphorylation in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003194 ATP + D-Fructose => ADP + D-Fructose 1-phosphate( EC:2.7.1.3 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003144 dADP + Phosphoenol-pyruvic acid => dATP + Pyruvic acid( EC:2.7.1.40 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0000490 Autophosphorylation http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003086 UTP + D-Glucose 1-phosphate = Pyrophosphate + UDP-D-glucose( EC:2.7.7.9 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0002990 GDP + D-Mannose 1-phosphate => GDP-D-mannose + Orthophosphate( EC:2.7.7.22 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003310 ATP + (R)-Mevalonic acid => ADP + (R)-Mevalonic acid 5-phosphate( EC:2.7.1.36 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0003179 ATP + GMP = ADP + GDP( EC:2.7.4.8 ) http://purl.obolibrary.org/obo/IEV_0000005 Phosphorylation http://purl.obolibrary.org/obo/IEV_0001732 Binding of 14-3-3 and HDAC7 in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0001698 Binding of 14-3-3 and HDAC5/7 in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0000414 Dephosphorylation in plasma membrane http://purl.obolibrary.org/obo/IEV_0000011 Dephosphorylation http://purl.obolibrary.org/obo/IEV_0001729 Dephosphorylation in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0000011 Dephosphorylation http://purl.obolibrary.org/obo/IEV_0000040 Dephosphorylation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000011 Dephosphorylation http://purl.obolibrary.org/obo/IEV_0002115 Nuclear import of ISGF3 http://purl.obolibrary.org/obo/IEV_0000048 Nuclear import of STAT dimer http://purl.obolibrary.org/obo/IEV_0002116 Nuclear import of STAT1 homodimer http://purl.obolibrary.org/obo/IEV_0000048 Nuclear import of STAT dimer http://purl.obolibrary.org/obo/IEV_0002117 Nuclear import of STAT3 homodimer http://purl.obolibrary.org/obo/IEV_0000048 Nuclear import of STAT dimer http://purl.obolibrary.org/obo/IEV_0002118 Nuclear import of STAT1:STAT3 heterodimer http://purl.obolibrary.org/obo/IEV_0000048 Nuclear import of STAT dimer http://purl.obolibrary.org/obo/IEV_0002119 Nuclear import of STAT5 homodimer http://purl.obolibrary.org/obo/IEV_0000048 Nuclear import of STAT dimer http://purl.obolibrary.org/obo/IEV_0002120 Nuclear import of STAT4 homodimer http://purl.obolibrary.org/obo/IEV_0000048 Nuclear import of STAT dimer http://purl.obolibrary.org/obo/IEV_0002299 Nuclear import of STAT6 homodimer http://purl.obolibrary.org/obo/IEV_0000048 Nuclear import of STAT dimer http://purl.obolibrary.org/obo/IEV_0003604 Nuclear import of STAT3:STAT4 heterodimer http://purl.obolibrary.org/obo/IEV_0000048 Nuclear import of STAT dimer http://purl.obolibrary.org/obo/IEV_0000453 Phosphorylation of p53 by ATM in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001082 Phosphorylation in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001074 Phosphorylation of RB by Cdk4/6 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001082 Phosphorylation in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001974 Phosphorylation of TCF by NLK in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001082 Phosphorylation in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003659 Phosphorylation of FOXO by AKT in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001082 Phosphorylation in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001081 Phosphorylation of RB by Cdk2 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001082 Phosphorylation in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002438 Activation of PKC delta by DAG in cytosol http://purl.obolibrary.org/obo/IEV_0002484 Activation of PKC by DAG in cytosol http://purl.obolibrary.org/obo/IEV_0001678 Caloric restriction http://purl.obolibrary.org/obo/IEV_0001679 Caloric treatment http://purl.obolibrary.org/obo/IEV_0001851 Negative regulation of AKT(PKB)-Bad signaling http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001852 Positive regulation of AKT(PKB)-Bad signaling http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001880 Deacetylation of histone by HDAC7 in nucleus http://purl.obolibrary.org/obo/IEV_0001876 Deacetylation of histone by HDAC5/7 in nucleus http://purl.obolibrary.org/obo/IEV_0001879 Deacetylation of histone by HDAC5 in nucleus http://purl.obolibrary.org/obo/IEV_0001876 Deacetylation of histone by HDAC5/7 in nucleus http://purl.obolibrary.org/obo/IEV_0001936 Palmitoylation of Wnt by Porcupine in ER http://purl.obolibrary.org/obo/IEV_0001937 Palmitoylation in ER http://purl.obolibrary.org/obo/IEV_0002579 Palmitoylation of hedgehog in ER http://purl.obolibrary.org/obo/IEV_0001937 Palmitoylation in ER http://purl.obolibrary.org/obo/IEV_0003509 Activation of DIF in cytosol http://purl.obolibrary.org/obo/IEV_0003859 Activation of NF-kappaB in cytosol http://purl.obolibrary.org/obo/IEV_0003531 Activation of Dorsal in cytosol http://purl.obolibrary.org/obo/IEV_0003859 Activation of NF-kappaB in cytosol http://purl.obolibrary.org/obo/IEV_0000837 Activation of NF-kappaB by Rac-GTP in cytosol http://purl.obolibrary.org/obo/IEV_0003859 Activation of NF-kappaB in cytosol http://purl.obolibrary.org/obo/IEV_0001307 Activation of NF-kappaB by Src family in cytosol http://purl.obolibrary.org/obo/IEV_0003859 Activation of NF-kappaB in cytosol http://purl.obolibrary.org/obo/IEV_0003523 Activation of DIF:Dorsal in cytosol http://purl.obolibrary.org/obo/IEV_0003859 Activation of NF-kappaB in cytosol http://purl.obolibrary.org/obo/IEV_0000906 Gene expression of Smad7 by R-Smad:Smad4 http://purl.obolibrary.org/obo/IEV_0000886 Gene expression of I-Smad by R-Smad:Smad4 http://purl.obolibrary.org/obo/IEV_0000518 Dephosphorylation of Lck_p by PEP in cytosol http://purl.obolibrary.org/obo/IEV_0001592 Dephosphorylation of Lck_p by PTP in cytosol http://purl.obolibrary.org/obo/IEV_0001108 Negative feedback regulation of p53 signaling pathway by Mdm2 http://purl.obolibrary.org/obo/IEV_0000463 Negative regulation of p53 signaling pathway http://purl.obolibrary.org/obo/IEV_0002450 Phosphorylation of ERK1/2 by MEK1/2(MKK1/2)_p in cytosol http://purl.obolibrary.org/obo/IEV_0000476 Phosphorylation of ERK by MEK1/2(MKK1/2)_p in cytosol http://purl.obolibrary.org/obo/IEV_0003579 Binding of BMP receptor complex and Smad1 in cytosol http://purl.obolibrary.org/obo/IEV_0003581 Binding of BMP receptor complex and R-Smad in cytosol http://purl.obolibrary.org/obo/IEV_0000949 Dissociation of Bid and Bcl-2 in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0000950 Dissociation in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0001893 Src inactivation signaling (through non-receptor kinase) http://purl.obolibrary.org/obo/IEV_0001642 Src inactivation signaling http://purl.obolibrary.org/obo/IEV_0001892 Src inactivation signaling (through PTP) http://purl.obolibrary.org/obo/IEV_0001642 Src inactivation signaling http://purl.obolibrary.org/obo/IEV_0002400 Binding of Angiotensin II and AT1R in extracellular http://purl.obolibrary.org/obo/IEV_0000662 Binding of GPCR ligand and GPCR in extracellular http://purl.obolibrary.org/obo/IEV_0002404 Binding of Glutamate and Group I mGlu receptor in extracellular http://purl.obolibrary.org/obo/IEV_0000662 Binding of GPCR ligand and GPCR in extracellular http://purl.obolibrary.org/obo/IEV_0003430 Binding of Adenosine and Adenosine A2A receptor in extracellular http://purl.obolibrary.org/obo/IEV_0000662 Binding of GPCR ligand and GPCR in extracellular http://purl.obolibrary.org/obo/IEV_0000473 Hydrolysis of PIP2 by PLC beta to generate DAG and IP3 in cytosol http://purl.obolibrary.org/obo/IEV_0000472 Hydrolysis of PIP2 by PLC to generate DAG and IP3 in cytosol http://purl.obolibrary.org/obo/IEV_0000268 Hydrolysis of PIP2 by PLC gamma to generate DAG and IP3 in cytosol http://purl.obolibrary.org/obo/IEV_0000472 Hydrolysis of PIP2 by PLC to generate DAG and IP3 in cytosol http://purl.obolibrary.org/obo/IEV_0000083 Development http://purl.obolibrary.org/obo/IEV_0000082 Organism event http://purl.obolibrary.org/obo/IEV_0000099 Tumorigenesis http://purl.obolibrary.org/obo/IEV_0000082 Organism event http://purl.obolibrary.org/obo/IEV_0000075 Disease http://purl.obolibrary.org/obo/IEV_0000082 Organism event http://purl.obolibrary.org/obo/IEV_0003460 Binding of DIF:Relish and NF-kappaB binding sequence in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000217 Binding of NF-kappaB and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003468 Binding of Relish and NF-kappaB binding sequence in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000217 Binding of NF-kappaB and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003512 Binding of DIF and NF-kappaB binding sequence in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000217 Binding of NF-kappaB and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003526 Binding of DIF:Dorsal and NF-kappaB binding sequence in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000217 Binding of NF-kappaB and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003534 Binding of Dorsal and NF-kappaB binding sequence in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000217 Binding of NF-kappaB and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000386 FK506 medication http://purl.obolibrary.org/obo/IEV_0000292 Medication http://purl.obolibrary.org/obo/IEV_0001567 Protein synthesis inhibitor medication http://purl.obolibrary.org/obo/IEV_0000292 Medication http://purl.obolibrary.org/obo/IEV_0001566 Anticancer drug medication http://purl.obolibrary.org/obo/IEV_0000292 Medication http://purl.obolibrary.org/obo/IEV_0000409 Removement of survival factor http://purl.obolibrary.org/obo/IEV_0000292 Medication http://purl.obolibrary.org/obo/IEV_0001571 Transcription inhibitor medication http://purl.obolibrary.org/obo/IEV_0000292 Medication http://purl.obolibrary.org/obo/IEV_0000294 Plant hormone medication http://purl.obolibrary.org/obo/IEV_0000292 Medication http://purl.obolibrary.org/obo/IEV_0001570 Proteasome inhibitor medication http://purl.obolibrary.org/obo/IEV_0000292 Medication http://purl.obolibrary.org/obo/IEV_0003873 Th2 cell proliferation http://purl.obolibrary.org/obo/IEV_0003872 T cell proliferation http://purl.obolibrary.org/obo/IEV_0003874 Th1 cell proliferation http://purl.obolibrary.org/obo/IEV_0003872 T cell proliferation http://purl.obolibrary.org/obo/IEV_0001124 Positive regulation of p53 degradation signaling http://purl.obolibrary.org/obo/IEV_0001669 Positive signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0001123 Negative regulation of p53 degradation signaling http://purl.obolibrary.org/obo/IEV_0001670 Negative signal transduction regulation pathway http://purl.obolibrary.org/obo/IEV_0002892 (S)-3-Hydroxy-butanoyl-CoA = Crotonoyl-CoA + H2O( EC:4.2.1.17 ) http://purl.obolibrary.org/obo/IEV_0002759 (3S)-3-hydroxyacyl-CoA = trans-2,3-Dehydroacyl-CoA + H2O( EC:4.2.1.17 ) http://purl.obolibrary.org/obo/IEV_0003003 3-Hydroxyisovaleryl-CoA = 3-Methylbut-2-enoyl-CoA + H2O( EC:4.2.1.17 ) http://purl.obolibrary.org/obo/IEV_0002759 (3S)-3-hydroxyacyl-CoA = trans-2,3-Dehydroacyl-CoA + H2O( EC:4.2.1.17 ) http://purl.obolibrary.org/obo/IEV_0003152 (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA = 2-Methylbut-2-enoyl-CoA + H2O( EC:4.2.1.17 ) http://purl.obolibrary.org/obo/IEV_0002759 (3S)-3-hydroxyacyl-CoA = trans-2,3-Dehydroacyl-CoA + H2O( EC:4.2.1.17 ) http://purl.obolibrary.org/obo/IEV_0003137 (S)-3-Hydroxyisobutyryl-CoA = 2-Methylprop-2-enoyl-CoA + H2O( EC:4.2.1.17 ) http://purl.obolibrary.org/obo/IEV_0002759 (3S)-3-hydroxyacyl-CoA = trans-2,3-Dehydroacyl-CoA + H2O( EC:4.2.1.17 ) http://purl.obolibrary.org/obo/IEV_0002872 3-Hydroxy-propanoyl-CoA = Propenoyl-CoA + H2O( EC:4.2.1.17 ) http://purl.obolibrary.org/obo/IEV_0002759 (3S)-3-hydroxyacyl-CoA = trans-2,3-Dehydroacyl-CoA + H2O( EC:4.2.1.17 ) http://purl.obolibrary.org/obo/IEV_0003049 Leukotriene C4 + Amino acid => Leukotriene D4 + 5-L-Glutamyl amino acid( EC:2.3.2.2 ) http://purl.obolibrary.org/obo/IEV_0002741 (5-L-glutamyl)-peptide + Amino acid = peptide + 5-L-glutamyl amino acid( EC:2.3.2.2 ) http://purl.obolibrary.org/obo/IEV_0001718 Binding of HDAC5 and MEF2 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001703 Binding of HDAC5/7 and MEF2 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001720 Binding of HDAC7 and MEF2 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001703 Binding of HDAC5/7 and MEF2 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001063 Palmitoylation in cytosol http://purl.obolibrary.org/obo/IEV_0000918 Palmitoylation http://purl.obolibrary.org/obo/IEV_0001064 Palmitoylation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000918 Palmitoylation http://purl.obolibrary.org/obo/IEV_0001937 Palmitoylation in ER http://purl.obolibrary.org/obo/IEV_0000918 Palmitoylation http://purl.obolibrary.org/obo/IEV_0003177 Acetyl-CoA + Putrescine => CoA + N-Acetyl-putrescine( EC:2.3.1.57 ) http://purl.obolibrary.org/obo/IEV_0003314 Acetyl-CoA + alkane-alpha,omega-diamine = CoA + N-acetyldiamine( EC:2.3.1.57 ) http://purl.obolibrary.org/obo/IEV_0001031 Cytosolic cation ion concentration decline http://purl.obolibrary.org/obo/IEV_0000771 Change in material concentration http://purl.obolibrary.org/obo/IEV_0002029 cAMP concentration decline http://purl.obolibrary.org/obo/IEV_0000771 Change in material concentration http://purl.obolibrary.org/obo/IEV_0002028 cAMP concentration elevation http://purl.obolibrary.org/obo/IEV_0000771 Change in material concentration http://purl.obolibrary.org/obo/IEV_0000234 p38 cascade http://purl.obolibrary.org/obo/IEV_0000445 MAPKKK cascade http://purl.obolibrary.org/obo/IEV_0001367 Binding of LAT_p and PLC gamma1 in cytosol http://purl.obolibrary.org/obo/IEV_0000267 Binding of LAT_p and PLC gamma in cytosol http://purl.obolibrary.org/obo/IEV_0001107 p53 signaling pathway (through GADD45) http://purl.obolibrary.org/obo/IEV_0001103 p53 signaling pathway http://purl.obolibrary.org/obo/IEV_0001114 p53 signaling pathway (through apoptotic factor) http://purl.obolibrary.org/obo/IEV_0001103 p53 signaling pathway http://purl.obolibrary.org/obo/IEV_0001022 Negative regulation of Caspase cascade (not through mitochondria) http://purl.obolibrary.org/obo/IEV_0001019 Negative regulation of Caspase cascade http://purl.obolibrary.org/obo/IEV_0000881 Positive regulation of TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0000879 Regulation of TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0000876 Regulation of TGF beta super family signaling pathway (through p38 cascade) http://purl.obolibrary.org/obo/IEV_0000879 Regulation of TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0000880 Negative regulation of TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0000879 Regulation of TGF beta super family signaling pathway http://purl.obolibrary.org/obo/IEV_0000185 Environmental event http://purl.obolibrary.org/obo/IEV_0000000 Event http://purl.obolibrary.org/obo/IEV_0000003 Biological event http://purl.obolibrary.org/obo/IEV_0000000 Event http://purl.obolibrary.org/obo/IEV_0000907 Transcription of Smad7 by R-Smad:Smad4 in nucleus http://purl.obolibrary.org/obo/IEV_0000901 Transcription of I-Smad by R-Smad:Smad4 in nucleus http://purl.obolibrary.org/obo/IEV_0000380 Physical stimulus treatment http://purl.obolibrary.org/obo/IEV_0000387 Treatment http://purl.obolibrary.org/obo/IEV_0000372 Radiation treatment http://purl.obolibrary.org/obo/IEV_0000387 Treatment http://purl.obolibrary.org/obo/IEV_0000371 Temperature treatment http://purl.obolibrary.org/obo/IEV_0000387 Treatment http://purl.obolibrary.org/obo/IEV_0000028 Chemical treatment http://purl.obolibrary.org/obo/IEV_0000387 Treatment http://purl.obolibrary.org/obo/IEV_0001563 Humidity treatment http://purl.obolibrary.org/obo/IEV_0000387 Treatment http://purl.obolibrary.org/obo/IEV_0001679 Caloric treatment http://purl.obolibrary.org/obo/IEV_0000387 Treatment http://purl.obolibrary.org/obo/IEV_0000292 Medication http://purl.obolibrary.org/obo/IEV_0000387 Treatment http://purl.obolibrary.org/obo/IEV_0001562 Osmotic pressure treatment http://purl.obolibrary.org/obo/IEV_0000387 Treatment http://purl.obolibrary.org/obo/IEV_0000953 Transcription of NOXA by E2F-1 in nucleus http://purl.obolibrary.org/obo/IEV_0001102 Transcription by E2F-1 in nucleus http://purl.obolibrary.org/obo/IEV_0000956 Transcription of PUMA by E2F-1 in nucleus http://purl.obolibrary.org/obo/IEV_0001102 Transcription by E2F-1 in nucleus http://purl.obolibrary.org/obo/IEV_0000850 Rac-GTP hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0000684 Small GTPase hydrolysis signaling http://purl.obolibrary.org/obo/IEV_0001537 gamma-Hexachlorocyclohexane degradation http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism http://purl.obolibrary.org/obo/IEV_0001545 Nitrobenzene degradation http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism http://purl.obolibrary.org/obo/IEV_0001538 3-Chloroacrylic acid degradation http://purl.obolibrary.org/obo/IEV_0001561 Xenobiotics Biodegradation and Metabolism http://purl.obolibrary.org/obo/IEV_0000531 Binding of SLP-76 and Itk in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000995 Binding of SMAC and IAP in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000845 Binding of RTK and Shc in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000029 Binding of Frizzled and DSH in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001024 Binding of CAD and ICAD in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003568 Binding of Estrogen and Estrogen receptor in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003463 Binding of IMD and FADD in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003754 Binding of Smo and beta-arrestin2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000404 Binding of Bad_p and 14-3-3 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001287 Binding of tyrosine-phosphorylated protein and PLC in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000590 Binding of vinculin and F actin in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000516 Binding of Csk and PEP in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002594 Binding of Sufu and Ci/Gli in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000937 Binding of DR4/5 and FADD in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000588 Binding of alpha-actinin and F actin in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000600 Binding of Fyn and Shc in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000572 Binding of PACAP and PACAP receptor in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003417 Dimerization of TRADD:TRAF2:RIP complex in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000599 Binding of FAK and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000255 Binding of TRADD and TRAF2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000844 Binding of RTK and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000242 Binding of MyD88 and IRAK in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000491 Binding of insulin receptor and Shc in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001381 Oligomerization of TRAF6 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001087 Binding of INK4 family and Cdk4/6 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000806 Binding of TNFR2 and TRAF1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000614 Binding of Shc_p and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000620 Binding of integrin complex and Ilk in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001306 Binding of calcium ion and calcineurin in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000679 Binding of small GTPase-GTP and GAP in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000051 Binding of cytokine receptor and JAK in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000129 Oligomerization of Bax in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000132 Binding of SOCS and JAK in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000152 Binding of SOCS and Cytokine receptor in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000189 Binding of NF-kappaB and specific modules in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000193 Binding of IL-1R complex and Tollip in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000200 Binding of IRAK1_p and TRAF6 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000201 Binding of IRAK1:TRAF6 and TAK1:TAB1:TAB2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000247 Binding of activated IRAK and TRAF6 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000248 Binding of TRAF6 and TAB1:TAB2:TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000254 Binding of TNFR1 trimer and TRADD in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000277 Trimerization of MALT1:CARMA1:BCL10 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000457 Binding of TRADD and FADD in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000483 Binding of calcium ion and PKC and active conformational change of PKC in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000494 Binding of IRS and insulin receptor in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000515 Binding of PAG/Cbp_p and Csk in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000582 Binding of integrin complex and talin in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000583 Complex formation of integrin-dependent membrane-skeletal protein in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000591 Binding of talin and F actin in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000597 Binding of FAK and Src family in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000598 Binding of p130Cas and Crk in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000609 Binding of Ras-GTP and PI3K in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000635 Complex formation of RhoG, Elmo and Dock180 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000644 Binding of vinculin and talin in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000667 Binding of G beta:G gamma and effector in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000775 Binding of melatonin and melatonin receptor in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000790 Binding of ligand and PPAR in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000827 Binding of Ras-GTP and RalGDS in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000858 Binding of Ral-GTP and Phospholipase D1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000891 Binding of Smad7:smurf2 and TGF beta type I receptor in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000896 Binding of Smad7:smurf1/2 and R-Smad in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000989 Apoptosome formation in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001228 Binding of Estrogen receptor alpha and p85 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001252 Binding of TCR-CD3 complex and non-receptor tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001284 Binding of Ig alpha and BLNK in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001297 Binding of BLNK and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001370 Binding of SLP-76 and Nck in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001371 Binding of Nck and PAK in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001380 Oligomerization of MALT1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001382 Binding of MALT1 and TRAF6 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001383 Binding of BCL10 and MALT1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001483 Binding of CD28 and PI3K in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001725 Binding of TRAF2 and MAPKKK in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001738 Binding of APC and beta catenin in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001774 Binding of Androgen receptor and Hsp90 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001802 Binding of AKT and Hsp90 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001805 Binding of Naked and DSH in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001806 Binding of Idax and DSH in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001808 Binding of TAB1 and TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001812 Binding of beta catenin and beta-TrCP in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001877 Binding of HDAC5 and importin alpha in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001951 Binding of Arrow/LRP5/6 and Axin in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001952 Binding of Dsh and Axin in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001953 Binding of Dsh and GBP/Frat and GSK-3 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001954 Complex formation of Axin, APC, GSK-3, Beta catenin and PP2A in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001967 Complex formation of Axin, APC, GSK-3 and Beta catenin in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001977 Binding of IRS and PI3K in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001983 Binding of GPCR and G alpha in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002069 Binding of Rap1 and B-Raf in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002074 Binding of G alpha-GDP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002093 Binding of Crk and Cbl in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002169 Binding of STAT1 and STAT2_p in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002181 Complex formation of Smad7 and smurf1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002182 Binding of Smad7:smurf1 and TGF beta receptor complex in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002194 Binding of LAT and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002195 Binding of RasGRP and DAG in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002306 Binding of Ig beta and Syk in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002310 Binding of BLNK, BTK, PLC gamma2, Vav and PIP3 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002312 Binding of PLC gamma2, BAM32 and PIP3 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002313 Binding of Btk and PIP3 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002314 Binding of BAM32 and PIP3 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002316 Binding of CD19 and PI3K in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002335 Binding of IL-7 R and PI3K in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002401 Binding of AT1R and G alpha q in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002411 Binding of TRAF6:TAK1:TAB1:TAB2 complex and ubiquitin ligase in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002430 Binding of TGF beta receptor I and XIAP in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002431 Binding of XIAP and TAB1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002456 Binding of Met_p and Src in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002457 Binding of Met_p and Gab1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002459 Binding of Gab1 and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002460 Binding of Gab1 and PLC gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002461 Binding of Gab1 and SHP-2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002463 Binding of Gab1 and Crk in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002464 Binding of Crk and Dock180 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002465 Binding of Dock180 and Rac in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002466 Binding of C3G and Rap1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002481 Binding of KDR_p and PI3K in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002482 Binding of KDR_p and VRAP in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002492 Binding of Grb2 and FRS2_p in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002494 Binding of Gab1_p and PI3K in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002495 Binding of Ras and PI3K in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002496 Binding of Ci/Gli and Slmb/beta-TrCP in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002498 Binding of BMP receptor I and XIAP in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002499 Binding of Smad6 and TAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002507 Binding of BMP receptor II and BAMBI in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002508 Binding of BMP receptor I and Smad7 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002509 Binding of BMP receptor I and Smad6 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002510 Binding of Smad1_p and Smad6 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002562 Binding of Notch (ICN) and Numb in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002595 Binding of Ci/Gli, Fu and Cos2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002620 Binding of Notch (ICN) and Deltex in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002717 Binding of cytokine receptor and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003352 Binding of ERK1/2_p and Mkp3 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003402 Binding of Fas and DAXX in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003428 Binding of Epac1 and cAMP in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003429 Binding of Epac1 and Rap1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003440 Binding of EPO receptor and PI3K in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003461 Binding of PGRP-LC and IMD in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003462 Binding of Dnr-1 and caspase8 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003499 Binding of Toll and MyD88:Tube in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003586 Complex formation of R-Smad and Co-Smad in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003592 Binding of TGF beta superfamily receptor complex and R-Smad in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003615 Binding of IL-5 receptor and Shc in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003617 Binding of IRS and IL-4 receptor in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003627 Binding of insulin receptor and PI3K in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003629 Binding of insulin receptor and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003637 Binding of eIF4F and mRNA in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003643 Complex formation of eIF4F in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003669 Binding of TORC1 and FKBP38 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003670 Binding of TSC1:TSC2 complex and TORC2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003696 Binding of trans-activator and PIAS in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003739 Binding of Sprouty and cbl in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003824 Binding of FGFR and adaptor protein in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003827 Binding of Dof and SHP-2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003835 Binding of Smo:beta-arrestin 2 and Kif3A in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003860 Binding of CDK and cyclin in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003892 Binding of PAK1 and Cdc42 and conformational change of PAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003895 Binding of PDGF receptor and PI3K in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003898 Binding of PDGF receptor and RasGAP in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000584 Binding of integrin complex and FAK in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000630 Binding of Crk and C3G in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000930 Homodimerization of Caspase8 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001005 Homodimerization of Caspase9 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001007 Caspase3/6/7 homodimer formation in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000528 Binding of Gads and SLP-76 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003820 Binding of PLC and tyrosine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003667 Binding of TORC1 and PRAS40 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003896 Binding of PDGF receptor and SHP-2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001010 Homodimerization of Caspase10 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000178 Binding of Cyt c and Apaf1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000925 Binding of Fas and FADD in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003891 Binding of Nck and NIK in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003443 Binding of CARMA1 and BCL10 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001736 Binding of AKT and GSK3beta in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000484 Binding of DAG, calcium ion and PKC and active conformational change of PKC in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003644 Binding of 4EBP-1 and eIF4E in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003458 Binding of FADD and caspase8 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000270 Binding of DAG and PKC and active conformational change of PKC in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001968 Complex formation of Axin, APC, GSK-3, CK1alpha and beta catenin in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000585 Binding of Integrin complex and tensin in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001299 Binding of BLNK and Vav in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001369 Binding of SLP-76 and Vav in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003757 Binding of Cos2, Fu, Ci/Gli, PKA, GSK3 and CK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000666 Binding of G alpha-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000241 Binding of TLR4:MD-2:CD14 and MyD88 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001245 Binding of calcium ion and calmodulin in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000990 Binding of Cyt c:Apaf1 and procaspase9 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003894 Binding of PDGF receptor and Crk in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002592 Binding of Smo and Cos2:Fu:Ci/Gli in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000195 Binding of IL1-R complex and MyD88 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003645 Binding of rapamycin:FKBP12 and TOR in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002715 Binding of ECSIT and MEKK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003567 Complex formation of Estrogen receptor in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002446 Binding of Sos and Ras in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001286 Binding of BLNK and PLC gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000890 Complex formation of Smad7 and smurf2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000934 Binding of TRADD and RIP in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003840 Binding of PAK1 and RhoGEF6 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000926 Binding of FADD and pro-caspase8/10 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001248 Binding of calcium calmodulin and CaMKII in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000400 Binding of c-AMP and PKA regulatory subunits and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001025 Binding of Caspase3/7/9 and IAP in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000831 Complex formation of PI3K, Eps8, Abi1 and Sos1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000603 Binding of Grb2 and Sos in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000592 Binding of alpha-actinin and zyxin in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002716 Binding of TRAF6 and ECSIT in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000214 Binding of NF-kappaB and I-kappaB in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000589 Binding of tensin and F actin in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003346 Binding of FGFR1 and Sef in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000267 Binding of LAT_p and PLC gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003897 Binding of PDGF receptor and Nck in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000586 Binding of FAK and paxillin in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0001305 Binding of calcium calmodulin and calcineurin in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000534 Binding of PIP2 and actin-binding protein in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000805 Binding of TNFR2 and TRAF2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000196 Binding of Tollip and IRAK1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003495 Binding of TRAF2 and Ref2P:aPKC in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0002170 Binding of STAT1:STAT2 heterodimer and IRF9 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003450 Binding of IRS_p and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003555 Binding of IGF-1 receptor_p and IRS-1 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003899 Binding of PDGF receptor and STAT5 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003358 Binding of Grb2 and Sprouty1_p in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000289 Binding of LAT_p and Gads in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000587 Binding of FAK and p130Cas in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003631 Binding of Ras-GTP and Raf in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000284 Binding of PLC and PIP3 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003339 Binding of Grb2 and Sprouty2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000932 Binding of TNFR1, TRADD, TRAF2 and RIP in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0003741 Binding of Sprouty and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000887 Binding of I-Smad and TGF beta receptor I in cytosol http://purl.obolibrary.org/obo/IEV_0000013 Binding in cytosol http://purl.obolibrary.org/obo/IEV_0000645 Binding of PIP2 and ERM in cytosol http://purl.obolibrary.org/obo/IEV_0000534 Binding of PIP2 and actin-binding protein in cytosol http://purl.obolibrary.org/obo/IEV_0000636 Binding of PIP2 and gelsolin in cytosol http://purl.obolibrary.org/obo/IEV_0000534 Binding of PIP2 and actin-binding protein in cytosol http://purl.obolibrary.org/obo/IEV_0000640 Binding of PIP2 and profilin in cytosol http://purl.obolibrary.org/obo/IEV_0000534 Binding of PIP2 and actin-binding protein in cytosol http://purl.obolibrary.org/obo/IEV_0000641 Binding of PIP2 and cofilin in cytosol http://purl.obolibrary.org/obo/IEV_0000534 Binding of PIP2 and actin-binding protein in cytosol http://purl.obolibrary.org/obo/IEV_0000642 Binding of PIP2 and actinin in cytosol http://purl.obolibrary.org/obo/IEV_0000534 Binding of PIP2 and actin-binding protein in cytosol http://purl.obolibrary.org/obo/IEV_0000643 Binding of PIP2 and vinculin in cytosol http://purl.obolibrary.org/obo/IEV_0000534 Binding of PIP2 and actin-binding protein in cytosol http://purl.obolibrary.org/obo/IEV_0002087 Phosphorylation of Raf by PKC in cytosol http://purl.obolibrary.org/obo/IEV_0002086 Phosphorylation of MAPKKK by non-receptor serine/threonine kinase in cytosol http://purl.obolibrary.org/obo/IEV_0000167 Bax activation signaling http://purl.obolibrary.org/obo/IEV_0000940 Apoptotic factor activation signaling http://purl.obolibrary.org/obo/IEV_0000963 Bmf activation signaling http://purl.obolibrary.org/obo/IEV_0000940 Apoptotic factor activation signaling http://purl.obolibrary.org/obo/IEV_0000941 BID activation signaling http://purl.obolibrary.org/obo/IEV_0000940 Apoptotic factor activation signaling http://purl.obolibrary.org/obo/IEV_0000955 PUMA activation signaling http://purl.obolibrary.org/obo/IEV_0000940 Apoptotic factor activation signaling http://purl.obolibrary.org/obo/IEV_0000959 Bim activation signaling http://purl.obolibrary.org/obo/IEV_0000940 Apoptotic factor activation signaling http://purl.obolibrary.org/obo/IEV_0000980 Bak activation signaling http://purl.obolibrary.org/obo/IEV_0000940 Apoptotic factor activation signaling http://purl.obolibrary.org/obo/IEV_0000951 NOXA activation signaling http://purl.obolibrary.org/obo/IEV_0000940 Apoptotic factor activation signaling http://purl.obolibrary.org/obo/IEV_0000406 Bad activation signaling http://purl.obolibrary.org/obo/IEV_0000940 Apoptotic factor activation signaling http://purl.obolibrary.org/obo/IEV_0001144 Transcription by p53 in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0000817 Transcription of c-fos by Elk-1 in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0000485 Transcription of IL-2 in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0001145 Transcription by Smad complex in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0001312 Transcription by NF-AT in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0001772 Transcription by Androgen receptor in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0001874 Transcription by MEF2 in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0002282 Transcription by beta-catenin:TCF complex in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0002284 Transcription by beta-catenin:TCF complex and Smad4 in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0002533 Transcription of cyclin D1 gene in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0002605 Transcription of Hh target gene in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0003337 Transcription of ETS target gene in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0003388 Transcription by AP-1 in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0003685 Transcription of Raptor gene in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0001076 Transcription by E2F in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0000050 Transcription by STAT dimer in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0001177 Transcription by CSL:Notch (NIC) in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0003661 Transcription of FOXO target gene in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0001308 Transcription by NF-kappaB in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0001221 Transcription by Estrogen receptor in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0003421 Transcription of c-FLIP gene in nucleus http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0002572 Autocleavage http://purl.obolibrary.org/obo/IEV_0002571 Cleavage http://purl.obolibrary.org/obo/IEV_0003409 Cleavage in extracellular http://purl.obolibrary.org/obo/IEV_0002571 Cleavage http://purl.obolibrary.org/obo/IEV_0003714 Cleavage in Golgi http://purl.obolibrary.org/obo/IEV_0002571 Cleavage http://purl.obolibrary.org/obo/IEV_0002601 Cleavage in cytosol http://purl.obolibrary.org/obo/IEV_0002571 Cleavage http://purl.obolibrary.org/obo/IEV_0000509 Dephosphorylation of Lck_p by CD45 and active conformational change http://purl.obolibrary.org/obo/IEV_0001599 Dephosphorylation of Lck_p by PTP and active conformational change in cytosol http://purl.obolibrary.org/obo/IEV_0003513 Expression of cecropin by DIF http://purl.obolibrary.org/obo/IEV_0003511 Expression of antimicrobial peptide by DIF http://purl.obolibrary.org/obo/IEV_0003514 Expression of diptericin by DIF http://purl.obolibrary.org/obo/IEV_0003511 Expression of antimicrobial peptide by DIF http://purl.obolibrary.org/obo/IEV_0003515 Expression of drosomycin by DIF http://purl.obolibrary.org/obo/IEV_0003511 Expression of antimicrobial peptide by DIF http://purl.obolibrary.org/obo/IEV_0003345 Negative feedback regulation of FGF8 signaling by Sef http://purl.obolibrary.org/obo/IEV_0003701 Negative regulation of FGFR1 signaling pathway http://purl.obolibrary.org/obo/IEV_0003357 Negative feedback regulation of FGF8 signaling by Sprouty1 http://purl.obolibrary.org/obo/IEV_0003701 Negative regulation of FGFR1 signaling pathway http://purl.obolibrary.org/obo/IEV_0003338 Negative feedback regulation of FGF8 signaling by Sprouty2 http://purl.obolibrary.org/obo/IEV_0003701 Negative regulation of FGFR1 signaling pathway http://purl.obolibrary.org/obo/IEV_0003351 Negative feedback regulation of FGF8 signaling by Mkp3 http://purl.obolibrary.org/obo/IEV_0003701 Negative regulation of FGFR1 signaling pathway http://purl.obolibrary.org/obo/IEV_0000390 Dissociation of E2F and RB_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001046 Dissociation in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001175 Dissociation of CSL and corepressor in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001046 Dissociation in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001873 Dissociation of HDAC5/7 and MEF2 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001046 Dissociation in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002273 Dissociation of Groucho and TCF in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001046 Dissociation in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003589 Dissociation of R-Smad and Smad4 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001046 Dissociation in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002861 ATP + L-Glutamic acid + NH3 = ADP + L-Glutamine + Orthophosphate( EC:6.3.1.2 ) http://purl.obolibrary.org/obo/IEV_0002675 Amidation http://purl.obolibrary.org/obo/IEV_0002167 Dissociation of IL-2 receptor and STAT5 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002162 Dissociation of IFN alpha receptor and STAT1 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002163 Dissociation of IFN alpha receptor and STAT3 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002164 Dissociation of IFN gamma receptor and STAT1 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002165 Dissociation of IL-6 receptor and STAT3 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002166 Dissociation of IL-10 receptor and STAT3 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002168 Dissociation of IL-12 receptor and STAT4 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002176 Dissociation of LIF receptor and STAT3 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002297 Dissociation of IL-4 receptor and STAT6 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002323 Dissociation of GH receptor and STAT5 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002329 Dissociation of IL-3 receptor and STAT5 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002333 Dissociation of IL-7 receptor and STAT5 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0003601 Dissociation of IL-23 receptor and STAT3 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0003602 Dissociation of IL-23 receptor and STAT4 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0003625 Dissociation of IL-5 receptor and STAT5 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0003626 Dissociation of IL-5 receptor and STAT1 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0003437 Dissociation of EPO receptor and STAT5 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0003439 Dissociation of EPO receptor and STAT3 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002660 Dissociation of TPO receptor and STAT3 in cytosol http://purl.obolibrary.org/obo/IEV_0002096 Dissociation of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0001707 AKT(PKB)-caspase signaling http://purl.obolibrary.org/obo/IEV_0001699 AKT signaling http://purl.obolibrary.org/obo/IEV_0001709 AKT(PKB)-FOXO signaling http://purl.obolibrary.org/obo/IEV_0001699 AKT signaling http://purl.obolibrary.org/obo/IEV_0000112 AKT(PKB)-TOR signaling http://purl.obolibrary.org/obo/IEV_0001699 AKT signaling http://purl.obolibrary.org/obo/IEV_0001727 AKT(PKB)-IKK signaling http://purl.obolibrary.org/obo/IEV_0001699 AKT signaling http://purl.obolibrary.org/obo/IEV_0003558 Binding of IRS-1_p and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0003450 Binding of IRS_p and Grb2 in cytosol http://purl.obolibrary.org/obo/IEV_0003588 Dephosphorylation of R-Smad in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001050 Dephosphorylation in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002026 Negative regulation of heteromeric GPCR signaling pathway (through G alpha i) http://purl.obolibrary.org/obo/IEV_0000669 Negative regulation of heterotrimeric GPCR signaling pathway http://purl.obolibrary.org/obo/IEV_0003884 Complex formation of BMP in ER http://purl.obolibrary.org/obo/IEV_0001035 Binding in ER http://purl.obolibrary.org/obo/IEV_0001040 Binding in inner space of ER http://purl.obolibrary.org/obo/IEV_0001035 Binding in ER http://purl.obolibrary.org/obo/IEV_0000273 Binding in ER membrane http://purl.obolibrary.org/obo/IEV_0001035 Binding in ER http://purl.obolibrary.org/obo/IEV_0000563 Ubiquitination of CD3_p by c-Cbl in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0000570 Ubiquitination of Lck by c-Cbl in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0000202 Ubiquitination of TRAF6 in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0000205 Ubiquitination of IRAK1_p in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0000212 Ubiquitination of I-kappaB_p in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0001389 Ubiquitination of NEMO by TRAF6 in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0002185 Ubiquitination of TGF beta receptor complex by smurf1 in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0002220 Ubiquitination of cytokine receptor by SOCS3 in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0002563 Ubiquitination of Notch by Su(dx)/Itch in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0003758 Ubiquitination of Ci/Gli by SCF ubiquitin ligase complex in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0003416 Ubiquitination of c-FLIP by Itch_p in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0000892 Ubiquitination of TGF beta receptor I by smurf2 in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0000897 Ubiquitination of R-Smad_Ub by smurf1/2 in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0001086 Ubiquitination of Cyclin E in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0000562 Ubiquitination of ZAP-70 by c-Cbl in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0000392 Ubiquitination of Cyclin D in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0001971 Ubiquitination of beta-catenin by SCF ubiquitin ligase complex in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0000567 Ubiquitination of Syk by c-Cbl in cytosol http://purl.obolibrary.org/obo/IEV_0000026 Ubiquitination in cytosol http://purl.obolibrary.org/obo/IEV_0002406 Dissociation of Group I mGlu receptor, G alpha q-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000749 Dissociation of G alpha q-GTP and G beta:G gamma in cytosol http://purl.obolibrary.org/obo/IEV_0000452 Insulin receptor signaling pathway (through IRS mediated signaling) http://purl.obolibrary.org/obo/IEV_0000487 Insulin receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0000126 Insulin receptor signaling pathway (through Shc mediated signaling) http://purl.obolibrary.org/obo/IEV_0000487 Insulin receptor signaling pathway http://purl.obolibrary.org/obo/IEV_0003379 Phosphorylation of ATF-2 by p38 in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000238 Phosphorylation of transcriptional regulator by p38_p in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001446 Steroid hormone biosynthesis http://purl.obolibrary.org/obo/IEV_0001553 Lipid Metabolism http://purl.obolibrary.org/obo/IEV_0003549 Transcription in nucleus http://purl.obolibrary.org/obo/IEV_0000183 Transcription http://purl.obolibrary.org/obo/IEV_0002959 IDP + H2O => IMP + Orthophosphate( EC:3.6.1.6 ) http://purl.obolibrary.org/obo/IEV_0002756 nucleoside diphosphate + H2O = nucleotide + Orthophosphate( EC:3.6.1.6 ) http://purl.obolibrary.org/obo/IEV_0003317 GDP + H2O => GMP + Orthophosphate( EC:3.6.1.6 ) http://purl.obolibrary.org/obo/IEV_0002756 nucleoside diphosphate + H2O = nucleotide + Orthophosphate( EC:3.6.1.6 ) http://purl.obolibrary.org/obo/IEV_0003316 UDP + H2O => UMP + Orthophosphate( EC:3.6.1.6 ) http://purl.obolibrary.org/obo/IEV_0002756 nucleoside diphosphate + H2O = nucleotide + Orthophosphate( EC:3.6.1.6 ) http://purl.obolibrary.org/obo/IEV_0001034 Dissociation in ER http://purl.obolibrary.org/obo/IEV_0000006 Dissociation http://purl.obolibrary.org/obo/IEV_0000023 Dissociation in cytosol http://purl.obolibrary.org/obo/IEV_0000006 Dissociation http://purl.obolibrary.org/obo/IEV_0000506 Dissociation in extracellular http://purl.obolibrary.org/obo/IEV_0000006 Dissociation http://purl.obolibrary.org/obo/IEV_0000665 Dissociation in plasma membrane http://purl.obolibrary.org/obo/IEV_0000006 Dissociation http://purl.obolibrary.org/obo/IEV_0001033 Dissociation in mitochondria http://purl.obolibrary.org/obo/IEV_0000006 Dissociation http://purl.obolibrary.org/obo/IEV_0001042 Dissociation in nucleus http://purl.obolibrary.org/obo/IEV_0000006 Dissociation http://purl.obolibrary.org/obo/IEV_0000507 Dissociation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000006 Dissociation http://purl.obolibrary.org/obo/IEV_0001156 Nuclear export of mRNA (p16) http://purl.obolibrary.org/obo/IEV_0003863 Nuclear export of mRNA (INK4 family) http://purl.obolibrary.org/obo/IEV_0001146 Nuclear export of mRNA (p15) http://purl.obolibrary.org/obo/IEV_0003863 Nuclear export of mRNA (INK4 family) http://purl.obolibrary.org/obo/IEV_0000903 Negative feedback regulation pathway of TGF beta superfamily signaling by (binding of I-Smad and TGF beta receptor I) http://purl.obolibrary.org/obo/IEV_0000885 Negative feedback regulation pathway of TGF beta superfamily signaling http://purl.obolibrary.org/obo/IEV_0000904 Negative feedback regulation pathway of TGF beta superfamily signaling by (R-Smad degradation through smurf1/2) http://purl.obolibrary.org/obo/IEV_0000885 Negative feedback regulation pathway of TGF beta superfamily signaling http://purl.obolibrary.org/obo/IEV_0001762 Negative feedback regulation pathway of TGF beta superfamily signaling by (Smad3 sumoylation by PIAS) http://purl.obolibrary.org/obo/IEV_0000885 Negative feedback regulation pathway of TGF beta superfamily signaling http://purl.obolibrary.org/obo/IEV_0000905 Negative feedback regulation pathway of TGF beta superfamily signaling by (TGF receptor degradation by smurf) http://purl.obolibrary.org/obo/IEV_0000885 Negative feedback regulation pathway of TGF beta superfamily signaling http://purl.obolibrary.org/obo/IEV_0002247 Phosphorylation of STAT dimer by serine kinase in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0001735 Phosphorylation in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0000025 Phosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0001735 Phosphorylation in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0000231 Phosphorylation in nucleus http://purl.obolibrary.org/obo/IEV_0001735 Phosphorylation in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0001700 Phosphorylation of HDAC5/7 by CaMK in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0001735 Phosphorylation in cytosol and/or nucleus http://purl.obolibrary.org/obo/IEV_0000821 Regulation of PDGF signaling pathway (through Grb2, Sos, Ras and Erk cascade) http://purl.obolibrary.org/obo/IEV_0001406 Regulation of PDGF signaling pathway http://purl.obolibrary.org/obo/IEV_0000839 Regulation of PDGF signaling pathway (through Grb2, Sos, Ras, PI3K, AKT and IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0001406 Regulation of PDGF signaling pathway http://purl.obolibrary.org/obo/IEV_0003699 Gene expression by ETS1/2 http://purl.obolibrary.org/obo/IEV_0003698 Gene expression by ets domain transcription factor http://purl.obolibrary.org/obo/IEV_0003700 Gene expression by Elk-1 http://purl.obolibrary.org/obo/IEV_0003698 Gene expression by ets domain transcription factor http://purl.obolibrary.org/obo/IEV_0003689 Translation of vvl in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0003720 Translation of Sprouty in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0001121 Translation of Mdm2 in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0000902 Translation of I-Smad in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0001662 Translation of apoptotic factor in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0002104 Translation of SOCS in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0002211 Translation of cytokine in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0003350 Translation of Sef in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0003356 Translation of Mkp3 in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0003423 Translation of c-FLIP in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0003706 Translation of Mae in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0003724 Translation of Argos gene in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0003728 Translation of Kek gene in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0003784 Translation of FGF receptor gene in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0003867 Translation of CKI in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0003788 Translation of SRF gene in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0002638 Translation of antimicrobial protein in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0001118 Translation of GADD45 in cytosol http://purl.obolibrary.org/obo/IEV_0003550 Translation in cytosol http://purl.obolibrary.org/obo/IEV_0000714 Clinical presentation http://purl.obolibrary.org/obo/IEV_0000075 Disease http://purl.obolibrary.org/obo/IEV_0001187 Jagged mediated Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0000164 Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0001186 Delta mediated Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0000164 Notch signaling pathway http://purl.obolibrary.org/obo/IEV_0003412 Caspase3 activation signaling (not through mitochondria) http://purl.obolibrary.org/obo/IEV_0001013 Caspase3/6/7 activation signaling (not through mitochondria) http://purl.obolibrary.org/obo/IEV_0000206 Proteasome degradation in plasma membrane http://purl.obolibrary.org/obo/IEV_0000010 Proteasome degradation http://purl.obolibrary.org/obo/IEV_0000021 Proteasome degradation in cytosol http://purl.obolibrary.org/obo/IEV_0000010 Proteasome degradation http://purl.obolibrary.org/obo/IEV_0000039 Proteasome degradation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000010 Proteasome degradation http://purl.obolibrary.org/obo/IEV_0001564 High osmotic pressure treatment http://purl.obolibrary.org/obo/IEV_0001562 Osmotic pressure treatment http://purl.obolibrary.org/obo/IEV_0002557 Binding of Notch1 and Delta1 in extracellular http://purl.obolibrary.org/obo/IEV_0001181 Binding of Notch and Delta in extracellular http://purl.obolibrary.org/obo/IEV_0001001 Dissociation of Caspase7 and SMAC:XIAP in cytosol http://purl.obolibrary.org/obo/IEV_0000997 Dissociation of Caspase and SMAC:IAP in cytosol http://purl.obolibrary.org/obo/IEV_0001002 Dissociation of Caspase9 and SMAC:XIAP in cytosol http://purl.obolibrary.org/obo/IEV_0000997 Dissociation of Caspase and SMAC:IAP in cytosol http://purl.obolibrary.org/obo/IEV_0000996 Dissociation of Caspase3 and SMAC:XIAP in cytosol http://purl.obolibrary.org/obo/IEV_0000997 Dissociation of Caspase and SMAC:IAP in cytosol http://purl.obolibrary.org/obo/IEV_0000690 Dissociation of G alpha i-GDP and adenylate cyclase in cytosol http://purl.obolibrary.org/obo/IEV_0000675 Dissociation of G alpha-GDP and target protein in cytosol http://purl.obolibrary.org/obo/IEV_0000737 Dissociation of G alpha t-GDP and cGMP PDE in cytosol http://purl.obolibrary.org/obo/IEV_0000675 Dissociation of G alpha-GDP and target protein in cytosol http://purl.obolibrary.org/obo/IEV_0000756 Dissociation of G alpha q-GDP and PLC beta in cytosol http://purl.obolibrary.org/obo/IEV_0000675 Dissociation of G alpha-GDP and target protein in cytosol http://purl.obolibrary.org/obo/IEV_0000688 Dissociation of G alpha s-GDP and adenylate cyclase in cytosol http://purl.obolibrary.org/obo/IEV_0000675 Dissociation of G alpha-GDP and target protein in cytosol http://purl.obolibrary.org/obo/IEV_0003694 Binding of BCL-6 and GAS in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002098 Binding of transcription factor and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000793 Binding of PPAR and PPRE in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002098 Binding of transcription factor and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000036 Binding of TCF/LEF and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002098 Binding of transcription factor and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000049 Binding of STAT dimer and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002098 Binding of transcription factor and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001176 Binding of CSL and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002098 Binding of transcription factor and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001207 Binding of Estrogen receptor and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002098 Binding of transcription factor and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0001770 Binding of Androgen receptor and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002098 Binding of transcription factor and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002097 Binding of AP-1 and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002098 Binding of transcription factor and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003336 Binding of ETS1/2_p and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002098 Binding of transcription factor and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003708 Binding of Tel-1 and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002098 Binding of transcription factor and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003773 Binding of Ci/Gli, CBP and Hedgehog target gene promoter in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002098 Binding of transcription factor and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000156 Binding of R-Smad:Smad4 complex, Coactivator and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002098 Binding of transcription factor and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0003660 Binding of FOXO and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002098 Binding of transcription factor and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000217 Binding of NF-kappaB and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002098 Binding of transcription factor and responsive element in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0002017 G alpha i GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002012 G alpha GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002003 G alpha s GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002012 G alpha GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002043 G alpha t GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002012 G alpha GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002031 G alpha q GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0002012 G alpha GDP-GTP exchange signaling http://purl.obolibrary.org/obo/IEV_0000486 Autophosphorylation in plasma membrane http://purl.obolibrary.org/obo/IEV_0000490 Autophosphorylation http://purl.obolibrary.org/obo/IEV_0000459 Autophosphorylation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000490 Autophosphorylation http://purl.obolibrary.org/obo/IEV_0000481 Autophosphorylation in cytosol http://purl.obolibrary.org/obo/IEV_0000490 Autophosphorylation http://purl.obolibrary.org/obo/IEV_0000759 Rhodopsin dark adaptation signaling http://purl.obolibrary.org/obo/IEV_0000121 Rhodopsin mediated signaling pathway http://purl.obolibrary.org/obo/IEV_0003333 Binding of FGFR1_p and FRS2 in cytosol http://purl.obolibrary.org/obo/IEV_0002490 Binding of FGFR_p and FRS2 in cytosol http://purl.obolibrary.org/obo/IEV_0003185 2 5-Amino-4-oxo-pentanoic acid => Porphobilinogen + 2 H2O( EC:4.2.1.24 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0001057 Lyase process in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0002947 D-Fructose 1-phosphate = Dihydroxy-acetone phosphate + D-Glyceraldehyde( EC:4.1.2.13 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0002923 5'-Phospho-ribosyl-4-(N-succino-carboxamide)-5-amino-imidazole = 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide + Fumaric acid( EC:4.3.2.2 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0002803 Hydroxy-methylbilane => Uroporphyrinogen III + H2O( EC:4.2.1.75 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0002835 D-Glycerate 2-phosphate = Phosphoenol-pyruvic acid + H2O( EC:4.2.1.11 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0002894 L-Cystathionine + H2O => L-Cysteine + 2-Oxo-butanoic acid + NH3( EC:4.4.1.1 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0002909 beta-D-Fructose 1,6-bisphosphate = Dihydroxy-acetone phosphate + D-Glyceraldehyde 3-phosphate( EC:4.1.2.13 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0002915 L-Serine => 2-Amino-acrylic acid + H2O( EC:4.3.1.17 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0002936 GTP => 3',5'-Cyclic GMP + Pyrophosphate( EC:4.6.1.2 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0003058 Leukotriene A4 + Glutathione => Leukotriene C4( EC:4.4.1.20 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0003128 L-Cystine + H2O => Thiocysteine + Pyruvic acid + NH3( EC:4.4.1.1 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0003218 Protoporphyrin IX + Fe2+ = Protoheme + 2 H+( EC:4.99.1.1 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0003230 L-Cysteine + H2O => Pyruvic acid + Hydrogen sulfide + NH3( EC:4.4.1.1 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0003256 ATP => 3',5'-Cyclic AMP + Pyrophosphate( EC:4.6.1.1 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0003257 L-Homocysteine + L-Serine => L-Cystathionine + H2O( EC:4.2.1.22 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0003290 L-Histidine = Urocanic acid + NH3( EC:4.3.1.3 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0003326 Citric acid = Isocitric acid( EC:4.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0001067 Decarboxylation http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0003019 (S)-3-Hydroxy-3-methyl-glutaryl-CoA = Acetyl-CoA + Acetoacetic acid( EC:4.1.3.4 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0002768 L-Arginino-succinic acid = L-Arginine + Fumaric acid( EC:4.3.2.1 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0003205 GTP => 3',5'-Cyclic GMP + Pyrophosphate( EC:4.6.1.1 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0002954 (S)-3-Hydroxy-3-methyl-glutaryl-CoA = 3-Methyl-glutaconyl-CoA + H2O( EC:4.2.1.18 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0003068 GDP-D-mannose => GDP-4-dehydro-6-deoxy-D-mannose + H2O( EC:4.2.1.47 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0002759 (3S)-3-hydroxyacyl-CoA = trans-2,3-Dehydroacyl-CoA + H2O( EC:4.2.1.17 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0002999 (R)-S-Lactoyl-glutathione = Glutathione + Methyl-glyoxal( EC:4.4.1.5 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0003178 5-Formimino-tetrahydro-folic acid + H+ = 5,10-Methenyl-tetrahydro-folic acid + NH3( EC:4.3.1.4 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0002820 (S)-Malic acid = Fumaric acid + H2O( EC:4.2.1.2 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0000203 Lyase process in cytosol http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0002922 Adenylo-succinic acid = AMP + Fumaric acid( EC:4.3.2.2 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0002865 L-Serine => Pyruvic acid + NH3( EC:4.3.1.17 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0003283 2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydro-pteridine triphosphate => 6-Pyruvoyl-5,6,7,8-tetrahydro-pterin + Triphosphate( EC:4.2.3.12 ) http://purl.obolibrary.org/obo/IEV_0000917 Lyase process http://purl.obolibrary.org/obo/IEV_0003484 Translation of drosomycin in cytosol http://purl.obolibrary.org/obo/IEV_0002638 Translation of antimicrobial protein in cytosol http://purl.obolibrary.org/obo/IEV_0003485 Translation of attacin in cytosol http://purl.obolibrary.org/obo/IEV_0002638 Translation of antimicrobial protein in cytosol http://purl.obolibrary.org/obo/IEV_0003486 Translation of cecropin in cytosol http://purl.obolibrary.org/obo/IEV_0002638 Translation of antimicrobial protein in cytosol http://purl.obolibrary.org/obo/IEV_0003489 Translation of diptericin in cytosol http://purl.obolibrary.org/obo/IEV_0002638 Translation of antimicrobial protein in cytosol http://purl.obolibrary.org/obo/IEV_0003488 Translation of drosocin in cytosol http://purl.obolibrary.org/obo/IEV_0002638 Translation of antimicrobial protein in cytosol http://purl.obolibrary.org/obo/IEV_0003487 Translation of defensin in cytosol http://purl.obolibrary.org/obo/IEV_0002638 Translation of antimicrobial protein in cytosol http://purl.obolibrary.org/obo/IEV_0003833 Binding of Ras-GTP and Raf1 in cytosol http://purl.obolibrary.org/obo/IEV_0003631 Binding of Ras-GTP and Raf in cytosol http://purl.obolibrary.org/obo/IEV_0002078 Binding of G alpha z-GTP and Rap1GAP1 in cytosol http://purl.obolibrary.org/obo/IEV_0002077 Binding of G alpha z-GTP and effector in cytosol http://purl.obolibrary.org/obo/IEV_0001331 Homeostasis http://purl.obolibrary.org/obo/IEV_0001330 Physiological event http://purl.obolibrary.org/obo/IEV_0000470 Binding of PLC beta and PIP3 in cytosol http://purl.obolibrary.org/obo/IEV_0000284 Binding of PLC and PIP3 in cytosol http://purl.obolibrary.org/obo/IEV_0000177 Negative regulation of Caspase cascade (through mitochondria) http://purl.obolibrary.org/obo/IEV_0001018 Regulation of Caspase cascade (through mitochondria) http://purl.obolibrary.org/obo/IEV_0002107 Binding of IFN alpha receptor and STAT2 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002108 Binding of IFN alpha receptor and STAT1 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002109 Binding of IFN alpha receptor and STAT3 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002110 Binding of IFN gamma receptor and STAT1 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002111 Binding of IL-6 receptor and STAT3 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002112 Binding of IL-10 receptor and STAT3 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002113 Binding of IL-2 receptor and STAT5 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002114 Binding of IL-12 receptor and STAT4 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002155 Binding of LIF receptor and STAT3 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002295 Binding of IL-4 receptor and STAT6 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002321 Binding of GH receptor and STAT5 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002328 Binding of IL-3 receptor and STAT5 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002332 Binding of IL-7 receptor and STAT5 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0002658 Binding of TPO receptor and STAT3 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0003436 Binding of EPO receptor and STAT5 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0003598 Binding of IL-23 receptor and STAT4 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0003624 Binding of IL-5 receptor and STAT1 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0003438 Binding of EPO receptor and STAT3 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0003599 Binding of IL-23 receptor and STAT3 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0003623 Binding of IL-5 receptor and STAT5 in cytosol http://purl.obolibrary.org/obo/IEV_0000046 Binding of cytokine receptor and STAT in cytosol http://purl.obolibrary.org/obo/IEV_0000033 Binding in mitochondria membrane http://purl.obolibrary.org/obo/IEV_0001036 Binding in mitochondria http://purl.obolibrary.org/obo/IEV_0001039 Binding in inner space of mitochondria http://purl.obolibrary.org/obo/IEV_0001036 Binding in mitochondria http://purl.obolibrary.org/obo/IEV_0000111 Skeletal muscle hypertrophy http://purl.obolibrary.org/obo/IEV_0000576 Organ morphogenesis http://purl.obolibrary.org/obo/IEV_0001399 Binding of Smad7 and TGF beta receptor I in cytosol http://purl.obolibrary.org/obo/IEV_0000887 Binding of I-Smad and TGF beta receptor I in cytosol http://purl.obolibrary.org/obo/IEV_0002223 Negative feedback regulation of JAK STAT pathway by (cytokine receptor degradation signaling) http://purl.obolibrary.org/obo/IEV_0002228 Negative feedback regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0002229 Negative feedback regulation of JAK STAT pathway by (JAK degradation signaling) http://purl.obolibrary.org/obo/IEV_0002228 Negative feedback regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000151 Negative feedback regulation of JAK STAT pathway by (binding of SOCS and cytokine receptor) http://purl.obolibrary.org/obo/IEV_0002228 Negative feedback regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0000143 Negative feedback regulation of JAK STAT pathway by (binding of SOCS and JAK) http://purl.obolibrary.org/obo/IEV_0002228 Negative feedback regulation of JAK STAT pathway http://purl.obolibrary.org/obo/IEV_0002192 Proteasome degradation of SnoN_ub by 26S proteasome http://purl.obolibrary.org/obo/IEV_0000039 Proteasome degradation in unidentified cellular location http://purl.obolibrary.org/obo/IEV_0002644 Expression of cecropin by Relish http://purl.obolibrary.org/obo/IEV_0003464 Expression of antimicrobial peptide by Relish http://purl.obolibrary.org/obo/IEV_0003472 Expression of diptericin by Relish http://purl.obolibrary.org/obo/IEV_0003464 Expression of antimicrobial peptide by Relish http://purl.obolibrary.org/obo/IEV_0003475 Expression of drosomycin by Relish http://purl.obolibrary.org/obo/IEV_0003464 Expression of antimicrobial peptide by Relish http://purl.obolibrary.org/obo/IEV_0003477 Expression of defensin by DIF:Relish http://purl.obolibrary.org/obo/IEV_0003464 Expression of antimicrobial peptide by Relish http://purl.obolibrary.org/obo/IEV_0003474 Expression of attacin by Relish http://purl.obolibrary.org/obo/IEV_0003464 Expression of antimicrobial peptide by Relish http://purl.obolibrary.org/obo/IEV_0003473 Expression of drosocin by Relish http://purl.obolibrary.org/obo/IEV_0003464 Expression of antimicrobial peptide by Relish http://purl.obolibrary.org/obo/IEV_0000376 Cold temperature treatment http://purl.obolibrary.org/obo/IEV_0000378 Low temperature treatment http://purl.obolibrary.org/obo/IEV_0002212 Chilling temperature treatment http://purl.obolibrary.org/obo/IEV_0000378 Low temperature treatment http://purl.obolibrary.org/obo/IEV_0000375 Freeze treatment http://purl.obolibrary.org/obo/IEV_0000378 Low temperature treatment http://purl.obolibrary.org/obo/IEV_0001041 Binding in inner space of nucleus http://purl.obolibrary.org/obo/IEV_0000015 Binding in nucleus http://purl.obolibrary.org/obo/IEV_0000017 Binding in nuclear membrane http://purl.obolibrary.org/obo/IEV_0000015 Binding in nucleus http://purl.obolibrary.org/obo/IEV_0002364 Activation of DIF [Drosophila] OBSOLETE: remap to 'Activation of DIF' IEV:0003509. http://purl.obolibrary.org/obo/IEV_0002289 Transcription by beta-catenin TCF complex (Xenopus) OBSOLETE: remap to 'Transcription by beta-catenin TCF complex' IEV:0002282. http://purl.obolibrary.org/obo/IEV_0002348 Activation of Spaetzle by PSH [Drosophila] OBSOLETE: remap to 'Activation of Spaetzle by PSH' IEV:0003503. http://purl.obolibrary.org/obo/IEV_0002376 Expression of antimicrobial peptide by Relish [Drosophila] OBSOLETE: remap to 'Expression of antimicrobial peptide by Relish' IEV:0003464. http://purl.obolibrary.org/obo/IEV_0001195 Activation of Deltex [Mammalian] Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, suggesting that it can antagonize NOTCH1. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. OBSOLETE: remap to 'Activation of Deltex' IEV:0003541. http://purl.obolibrary.org/obo/IEV_0002350 Dimerization of Toll by Spaetzle [Drosophila] OBSOLETE: remap to 'Dimerization of Toll by Spaetzle' IEV:0003529. http://purl.obolibrary.org/obo/IEV_0002649 Transcription of drosomycin by Relish [Drosophila] OBSOLETE: remap to 'Transcription of drosomycin by Relish' IEV:0003479. http://purl.obolibrary.org/obo/IEV_0002366 Activation of DIF:Dorsal [Drosophila] OBSOLETE: remap to 'Activation of DIF:Dorsal' IEV:0003523. http://purl.obolibrary.org/obo/IEV_0002391 Cleavage and activation of Relish by Dredd [Drosophila] OBSOLETE: remap to 'Cleavage and activation of Relish by caspase8' IEV:0003467. http://purl.obolibrary.org/obo/IEV_0002369 Binding of DIF:Dorsal and NF-kappaB binding sequence [Drosophila] OBSOLETE: remap to 'Binding of DIF:Dorsal and NF-kappaB binding sequence' IEV:0003526. http://purl.obolibrary.org/obo/IEV_0003370 Expression of drosomycin by Dorsal [Drosophila] OBSOLETE: remap to 'Expression of drosomycin by Dorsal' IEV:0003535. http://purl.obolibrary.org/obo/IEV_0002650 Translation of drosomycin [Drosophila] OBSOLETE: remap to 'Translation of drosomycin' IEV:0003484. http://purl.obolibrary.org/obo/IEV_0002359 Dissociation of Cactus_p and DIF [Drosophila] OBSOLETE: remap to 'Dissociation of Cactus_p and DIF' IEV:0003510. http://purl.obolibrary.org/obo/IEV_0001065 Interaction in cytosol OBSOLETE: remap to 'Unknown interaction' IEV:0000922. http://purl.obolibrary.org/obo/IEV_0003920 angiogenesis Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. http://purl.obolibrary.org/obo/IEV_0000087 Inhibition of Adipocyte differentiation Any process that stops, prevents or reduces the rate, frequency or extent of adipocyte differentiation. http://purl.obolibrary.org/obo/IEV_0000556 Regulation of Ras-Raf-MAPK signaling by spred [Drosophila] OBSOLETE: remap to 'Regulation of Ras-Raf-MAPK signaling by spred' IEV:0003543. http://purl.obolibrary.org/obo/IEV_0000557 Positive regulation of Ras-Raf-MAPK signaling by spred (Drosophila) OBSOLETE: remap to 'Positive regulation of Ras-Raf-MAPK signaling by spred' IEV:0003545. http://purl.obolibrary.org/obo/IEV_0000746 Adaptation of rhodopsin mediated signaling Process by which the visual system can modulate its sensitivity and response to light stimuli (that might vary over more than 6 magnitudes in intensity) without response saturation. http://purl.obolibrary.org/obo/IEV_0001066 Interaction in unidentified cellular location OBSOLETE: remap to 'Unknown interaction' IEV:0000922. http://purl.obolibrary.org/obo/IEV_0001197 Activation of Numb [Mammalian] OBSOLETE: remap to 'Activation of Numb' IEV:0003542. http://purl.obolibrary.org/obo/IEV_0001593 Interaction in the inner space of the nuclear OBSOLETE: remap to 'Unknown interaction' IEV:0000922. http://purl.obolibrary.org/obo/IEV_0001821 Regulation of blood vessel size Any process that modulates the size of blood vessels. http://purl.obolibrary.org/obo/IEV_0002217 Cellulose biosynthesis The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. http://purl.obolibrary.org/obo/IEV_0002268 Wnt signaling pathway (Mammalia) OBSOLETE: remap to 'Wnt signaling pathway' IEV:0000027. http://purl.obolibrary.org/obo/IEV_0002269 Wnt signaling pathway (Drosophila) OBSOLETE: remap to 'Wnt signaling pathway' IEV:0000027. http://purl.obolibrary.org/obo/IEV_0002270 C. elegans endoderm induction Wnt signaling pathway OBSOLETE: remap to 'Endoderm induction Wnt signaling pathway' IEV:0003455. http://purl.obolibrary.org/obo/IEV_0002285 Transcription by beta-catenin TCF complex and Smad4 (Xenopus) OBSOLETE: remap to 'Transcription by beta-catenin TCF complex and Smad4' IEV:0002284. http://purl.obolibrary.org/obo/IEV_0002286 Transcription by beta-catenin TCF complex (Mammals) OBSOLETE: remap to 'Transcription by beta-catenin TCF complex' IEV:0002282. http://purl.obolibrary.org/obo/IEV_0002287 Transcription by beta-catenin TCF complex (Drosophila) OBSOLETE: remap to 'Transcription by beta-catenin TCF complex' IEV:0002282. http://purl.obolibrary.org/obo/IEV_0002288 Transcription by beta-catenin TCF complex and Smad4 (Mammals) OBSOLETE: remap to 'Transcription by beta-catenin TCF complex and Smad4' IEV:0002284. http://purl.obolibrary.org/obo/IEV_0002341 Binding of PGRP-SA and GNBP1 [Drosophila] OBSOLETE: remap to 'Binding of PGRP-SA and GNBP1' IEV:0003496. http://purl.obolibrary.org/obo/IEV_0002342 Binding of PGRP-SA:GNBP1 and PGN [Drosophila] OBSOLETE: remap to 'Binding of PGRP-SA:GNBP1 and PGN' IEV:0003497. http://purl.obolibrary.org/obo/IEV_0002343 Binding of PGRP-SD and PGN [Drosophila] OBSOLETE: remap to 'Binding of PGRP-SD and PGN' IEV:0003498. http://purl.obolibrary.org/obo/IEV_0002344 Binding of GNBP3 and beta1-3 glucan [Drosophila] OBSOLETE: remap to 'Binding of GNBP3 and beta1-3 glucan' IEV:0003494. http://purl.obolibrary.org/obo/IEV_0002345 Activation of serine protease [Drosophila] OBSOLETE: remap to 'Activation of serine protease' IEV:0003491. http://purl.obolibrary.org/obo/IEV_0002346 Activation of PSH by GNBP3 [Drosophila] OBSOLETE: remap to 'Activation of PSH by GNBP3' IEV:0003492. http://purl.obolibrary.org/obo/IEV_0002347 Activation of Spaetzle by serine protease [Drosophila] OBSOLETE: remap to 'Activation of Spaetzle by serine protease' IEV:0003504. http://purl.obolibrary.org/obo/IEV_0002349 Binding of Toll and Spaetzle [Drosophila] OBSOLETE: remap to 'Binding of Toll and Spaetzle' IEV:0003500. http://purl.obolibrary.org/obo/IEV_0002351 Binding of Toll and dMyD88:Tube [Drosophila] OBSOLETE: remap to 'Binding of Toll and MyD88:Tube' IEV:0003499. http://purl.obolibrary.org/obo/IEV_0002352 Binding of Toll:dMyD88:Tube and Pelle [Drosophila] OBSOLETE: remap to 'Binding of Toll:MyD88:Tube and Pelle' IEV:0003501. http://purl.obolibrary.org/obo/IEV_0002355 Phosphorylation of dTRAF2 by Pelle_p [Drosophila] OBSOLETE: remap to 'Phosphorylation of TRAF2 by Pelle_p' IEV:0003540. http://purl.obolibrary.org/obo/IEV_0002356 Binding of dTRAF2 and Ref(2):DaPKC [Drosophila] OBSOLETE: remap to 'Binding of TRAF2 and Ref(2):DaPKC' IEV:0003495. http://purl.obolibrary.org/obo/IEV_0002357 Nuclear import of dTRAF2:Ref(2)P:DaPKC [Drosophila] OBSOLETE: remap to 'Nuclear import of TRAF2:Ref(2)P:DaPKC' IEV:0003539. http://purl.obolibrary.org/obo/IEV_0002358 Phosphorylation of Cactus [Drosophila] OBSOLETE: remap to 'Phosphorylation of Cactus' IEV:0003522. http://purl.obolibrary.org/obo/IEV_0002361 Nuclear import of DIF [Drosophila] OBSOLETE: remap to 'Nuclear import of DIF' IEV:0003521. http://purl.obolibrary.org/obo/IEV_0002362 Nuclear import of Dorsal [Drosophila] OBSOLETE: remap to 'Nuclear import of Dorsal' IEV:0003538. http://purl.obolibrary.org/obo/IEV_0002363 Nuclear import of Dorsal:DIF [Drosophila] OBSOLETE: remap to 'Nuclear import of Dorsal:DIF' IEV:0003528. http://purl.obolibrary.org/obo/IEV_0002365 Activation of Dorsal [Drosophila] OBSOLETE: remap to 'Activation of Dorsal' IEV:0003531. http://purl.obolibrary.org/obo/IEV_0002367 Binding of DIF and NF-kappaB binding sequence [Drosophila] OBSOLETE: remap to 'Binding of DIF and NF-kappaB binding sequence' IEV:0003512. http://purl.obolibrary.org/obo/IEV_0002368 Binding of Dorsal and NF-kappaB binding sequence [Drosophila] OBSOLETE: remap to 'Binding of Dorsal and NF-kappaB binding sequence' IEV:0003534. http://purl.obolibrary.org/obo/IEV_0002370 Transcription of antimicrobial peptide by DIF [Drosophila] OBSOLETE: remap to 'Transcription of antimicrobial peptide by DIF' IEV:0003517. http://purl.obolibrary.org/obo/IEV_0002371 Transcription of antimicrobial peptide by Dorsal [Drosophila] OBSOLETE: remap to 'Transcription of antimicrobial peptide by Dorsal' IEV:0003537. http://purl.obolibrary.org/obo/IEV_0002372 Transcription of antimicrobial peptide by DIF:Dorsal [Drosophila] OBSOLETE: remap to 'Transcription of antimicrobial peptide by DIF:Dorsal' IEV:0003527. http://purl.obolibrary.org/obo/IEV_0002373 DIF signaling [Drosophila] OBSOLETE: remap to 'DIF signaling' IEV:0003506. http://purl.obolibrary.org/obo/IEV_0002374 Dorsal signaling [Drosophila] OBSOLETE: remap to 'Dorsal signaling' IEV:0003507. http://purl.obolibrary.org/obo/IEV_0002377 Expression of drosomycin by Relish [Drosophila] OBSOLETE: remap to 'Expression of drosomycin by Relish' IEV:0003475. http://purl.obolibrary.org/obo/IEV_0002378 Expression of cecropin by Relish [Drosophila] OBSOLETE: remap to 'Expression of cecropin by Relish' IEV:0002644. http://purl.obolibrary.org/obo/IEV_0002379 Expression of diptericin by Relish [Drosophila] OBSOLETE: remap to 'Expression of diptericin by Relish' IEV:0003472. http://purl.obolibrary.org/obo/IEV_0002381 Binding of PGRP-LC and PGN [Drosophila] OBSOLETE: remap to 'Binding of PGRP-LC and PGN' IEV:0003465. http://purl.obolibrary.org/obo/IEV_0002382 Binding of PGRP-LC and LPS [Drosophila] OBSOLETE: remap to 'Binding of PGRP-LC and LPS' IEV:0003457. http://purl.obolibrary.org/obo/IEV_0002383 Binding of PGRP-LE and PGN [Drosophila] OBSOLETE: remap to 'Binding of PGRP-LE and PGN' IEV:0003466. http://purl.obolibrary.org/obo/IEV_0002384 Binding of PGRP-LC and IMD [Drosophila] OBSOLETE: remap to 'Binding of PGRP-LC and IMD' IEV:0003461. http://purl.obolibrary.org/obo/IEV_0002385 Binding of IMD and dFADD [Drosophila] OBSOLETE: remap to 'Binding of IMD and FADD' IEV:0003463. http://purl.obolibrary.org/obo/IEV_0002386 Binding of dFADD and Dredd [Drosophila] OBSOLETE: remap to 'Binding of FADD and caspase8' IEV:0003458. http://purl.obolibrary.org/obo/IEV_0002387 Binding of Dnr-1 and Dredd [Drosophila] OBSOLETE: remap to 'Binding of Dnr-1 and caspase8' IEV:0003462. http://purl.obolibrary.org/obo/IEV_0002390 Phosphorylation of Relish by IKK [Drosophila] OBSOLETE: remap to 'Phosphorylation of Relish by IKK' IEV:0003469. http://purl.obolibrary.org/obo/IEV_0002392 Nuclear import of Relish [Drosophila] OBSOLETE: remap to 'Nuclear import of Relish' IEV:0003471. http://purl.obolibrary.org/obo/IEV_0002395 Expression of drosocin by Relish [Drosophila] OBSOLETE: remap to 'Expression of drosocin by Relish' IEV:0003473. http://purl.obolibrary.org/obo/IEV_0002396 Expression of attacin by Relish [Drosophila] OBSOLETE: remap to 'Expression of attacin by Relish' IEV:0003474. http://purl.obolibrary.org/obo/IEV_0002397 Expression of defensin by DIF:Relish [Drosophila] OBSOLETE: remap to 'Expression of defensin by DIF:Relish' IEV:0003477. http://purl.obolibrary.org/obo/IEV_0002398 Dissociation of Cactus_p and Dorsal [Drosophila] OBSOLETE: remap to 'Dissociation of Cactus_p and Dorsal' IEV:0003532. http://purl.obolibrary.org/obo/IEV_0002407 Dissociation of NF-kappaB and I-kappaB [mammals] OBSOLETE: remap to 'Dissociation of NF-kappaB and I-kappaB' IEV:0000215. http://purl.obolibrary.org/obo/IEV_0002410 Phosphorylation of I-kappaB_p by IKK complex_p [mammals] OBSOLETE: remap to 'Phosphorylation of I-kappaB_p by IKK complex_p in cytosol' IEV:0000213. http://purl.obolibrary.org/obo/IEV_0002511 Binding of DIF:Relish and NF-kappaB binding sequence [Drosophila] OBSOLETE: remap to 'Binding of DIF:Relish and NF-kappaB binding sequence' IEV:0003460. http://purl.obolibrary.org/obo/IEV_0002512 Transcription of defensin by DIF:Relish [Drosophila] OBSOLETE: remap to 'Transcription of defensin by DIF:Relish' IEV:0003481. http://purl.obolibrary.org/obo/IEV_0002535 Cell fate determination Process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment. http://purl.obolibrary.org/obo/IEV_0002549 Wnt signaling pathway (C. elegans) OBSOLETE: remap to 'Wnt signaling pathway' IEV:0000027. http://purl.obolibrary.org/obo/IEV_0002551 Transcription by beta-catenin TCF complex (C. elegans) OBSOLETE: remap to 'Transcription by beta-catenin TCF complex' IEV:0002282. http://purl.obolibrary.org/obo/IEV_0002599 Cell fate commitment The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. http://purl.obolibrary.org/obo/IEV_0002622 Dissociation of Axin, APC, GSK3beta and beta-catenin OBSOLETE: remap to 'Dissociation of Axin, APC, GSK3beta and beta-catenin in cytosol' IEV:0003870. http://purl.obolibrary.org/obo/IEV_0002639 Translation of Defensin [Drosophila] OBSOLETE: remap to 'Translation of Defensin' IEV:0003487. http://purl.obolibrary.org/obo/IEV_0002640 Transcription of drosocin by Relish [Drosophila] OBSOLETE: remap to 'Transcription of drosocin by Relish' IEV:0003482. http://purl.obolibrary.org/obo/IEV_0002641 Translation of drosocin [Drosophila] OBSOLETE: remap to 'Translation of drosocin' IEV:0003488. http://purl.obolibrary.org/obo/IEV_0002645 Transcription of cecropin by Relish [Drosophila] OBSOLETE: remap to 'Transcription of cecropin by Relish' IEV:0003480. http://purl.obolibrary.org/obo/IEV_0002647 Transcription of diptericin by Relish [Drosophila] OBSOLETE: remap to 'Transcription of diptericin by Relish' IEV:0003483. http://purl.obolibrary.org/obo/IEV_0002648 Translation of diptericin [Drosophila] OBSOLETE: remap to 'Translation of diptericin' IEV:0003489. http://purl.obolibrary.org/obo/IEV_0002683 suppression A supressed gene mutation cause of an altered phenotype that is reverted to wild type phenotype when cell also carry a suppressor gene with a specific mutation or altered expression level. OBSOLETE: remap to CV intraction type 'suppressive interaction' MI:0796. http://purl.obolibrary.org/obo/IEV_0002685 suppression overexpression Overexpression is the suppressor of a phenotpe. OBSOLETE: remap to CV intraction type 'suppressive interaction' MI:0796 and genetic experimental form 'over expressed' MI:0506. http://purl.obolibrary.org/obo/IEV_0002689 suppression partial alteration A mutation is the partial suppressor of a mutant phenotype. OBSOLETE: remap to CV intraction type 'suppressive interaction' MI:0796 and genetic experimental form 'knock down' MI:0789. http://purl.obolibrary.org/obo/IEV_0002690 synthetic phenotype Two silent mutations show an altered phenotype when they co-occur on the same cell. OBSOLETE: remap to CV intraction type 'synthetic interaction' MI:0794. http://purl.obolibrary.org/obo/IEV_0002691 synthetic lethal Death phenotype observed on cells carrying combination of two independently silent mutations. OBSOLETE: remap to CV intraction type 'synthetic interaction' MI:0794 and external CV for phenotype description (lethal FBcv:0000351) http://purl.obolibrary.org/obo/IEV_0002693 conditional synthetic lethal Two silent mutations show a conditional synthetic lethal phenotype when they co-occur on the same cell. OBSOLETE: remap to CV intraction type 'synthetic interaction' MI:0794 and external CV for phenotype description (lethal FBcv:0000351) http://purl.obolibrary.org/obo/IEV_0002694 suppression scalable Level of over/underexpression scales the 'extend' of a phenotype. OBSOLETE: remap to CV intraction type 'suppressive interaction' MI:0796 and genetic experimental form 'expression level alteration' MI:0803. http://purl.obolibrary.org/obo/IEV_0002695 conditional synthetic lethal nutrition-sensitivity Two silent mutations show a nutrition sensitive lethal phenotype when they co-occur on the same cell. OBSOLETE: remap to CV intraction type 'synthetic interaction' MI:0794 and external CV for phenotype description. http://purl.obolibrary.org/obo/IEV_0002696 conditional synthetic lethal temperature-sensitivity Two silent mutations show a temperature sensitive lethal phenotype when they co-occur on the same cell. OBSOLETE: remap to CV intraction type 'synthetic interaction' MI:0794 and external CV for phenotype description (FBcv:0000310 'temperature conditional') http://purl.obolibrary.org/obo/IEV_0002697 synthetic growth defect Two silent mutations show growth defect when they co-occur on the same cell. OBSOLETE: remap to CV intraction type 'synthetic interaction' MI:0794 and external CV for phenotype description ( FBcv:0000427 'cell growth defective') http://purl.obolibrary.org/obo/IEV_0002698 synthetic growth increase Two silent mutations show growth increase when they co-occur on the same cell. OBSOLETE: remap to CV intraction type 'synthetic interaction' MI:0794 and external CV for phenotype description ( FBcv:0000427 'cell growth defective') http://purl.obolibrary.org/obo/IEV_0003328 FGF8 signaling pathway(Xenopus) OBSOLETE: remap to 'FGF8 signaling pathway' IEV:0003405. http://purl.obolibrary.org/obo/IEV_0003329 FGF8 signaling pathway(Mouse) OBSOLETE: remap to 'FGF8 signaling pathway' IEV:0003405. http://purl.obolibrary.org/obo/IEV_0003365 Expression of cecropin by DIF [Drosophila] OBSOLETE: remap to 'Expression of cecropin by DIF' IEV:0003513. http://purl.obolibrary.org/obo/IEV_0003366 Expression of drosomycin by DIF [Drosophila] OBSOLETE: remap to 'Expression of drosomycin by DIF' IEV:0003515. http://purl.obolibrary.org/obo/IEV_0003368 Expression of antimicrobial peptide by DIF:Dorsal [Drosophila] OBSOLETE: remap to 'Expression of antimicrobial peptide by DIF:Dorsal' IEV:0003525. http://purl.obolibrary.org/obo/IEV_0003371 Transcription of drosomycin by Dorsal [Drosophila] OBSOLETE: remap to 'Transcription of drosomycin by Dorsal' IEV:0003536. http://purl.obolibrary.org/obo/IEV_0003372 Transcription of cecropin by DIF [Drosophila] OBSOLETE: remap to 'Transcription of cecropin by DIF' IEV:0003516. http://purl.obolibrary.org/obo/IEV_0003373 Transcription of drosomycin by DIF [Drosophila] OBSOLETE: remap to 'Transcription of drosomycin by DIF' IEV:0003519. http://purl.obolibrary.org/obo/IEV_0003374 Transcription of diptericin by DIF [Drosophila] OBSOLETE: remap to 'Transcription of diptericin by DIF' IEV:0003520. http://purl.obolibrary.org/obo/IEV_0003411 Cleavage of Spaetzle by PSH [Drosophila] OBSOLETE: remap to 'Cleavage of Spaetzle by PSH' IEV:0003505. http://purl.obolibrary.org/obo/IEV_0003882 Ectoderm formation The formation of ectoderm during gastrulation. http://purl.obolibrary.org/obo/IEV_0003917 Oligodendrocyte development The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system. http://purl.obolibrary.org/obo/IEV_0000747 Deactivation of rhodopsin mediated signaling The process of restoring the photoreceptor cell to its unexcited state after termination of the stimulus (photon). http://purl.obolibrary.org/obo/IEV_0000088 Negative regulation of myoblast differentiation Any process that stops, prevents or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/IEV_0003364 Expression of antimicrobial peptide by DIF [Drosophila] OBSOLETE: remap to 'Expression of antimicrobial peptide by DIF' IEV:0003511. http://purl.obolibrary.org/obo/IEV_0002654 Transcription of antimicrobial peptide [Drosophila] OBSOLETE: remap to 'Transcription of antimicrobial peptide' IEV:0003518. http://purl.obolibrary.org/obo/IEV_0002687 suppression mutation a given (suppressed) mutation phenotype is reverted by a supressor gene mutation. OBSOLETE: remap to CV intraction type 'suppressive interaction' MI:0796 and genetic experimental form 'mutated gene' MI:0804. http://purl.obolibrary.org/obo/IEV_0002692 synthetic growth effect Two silent mutations show altered growth effect when they co-occur on the same cell. OBSOLETE: remap to CV intraction type 'synthetic interaction' MI:0794 and external CV for phenotype description ( FBcv:0000427 'cell growth defective') http://purl.obolibrary.org/obo/IEV_0002684 suppression expression alteration An altered expression is the suppressor of a phenotype. OBSOLETE: remap to CV intraction type 'suppressive interaction' MI:0796 and genetic experimental form 'expression level alteration' MI:0803. http://purl.obolibrary.org/obo/IEV_0001255 Receptor recycling The process by which receptor molecules are returned to an active state and in an active cellular location after they have been stimulated by a ligand. An active state is when the receptor is ready to receive a signal. http://purl.obolibrary.org/obo/IEV_0003881 Amnioserosa formation Formation of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. This occurs by the transformation of a narrow strip of cells at the dorsal midline of the blastoderm from columnar to squamous cells, accompanied by a lateral shift. http://purl.obolibrary.org/obo/IEV_0002360 Dissociation of Cactus_p and Dorsal:DIF [Drosophila] OBSOLETE: remap to 'Dissociation of Cactus_p and Dorsal:DIF' IEV:0003524. http://purl.obolibrary.org/obo/IEV_0003367 Expression of diptericin by DIF [Drosophila] OBSOLETE: remap to 'Expression of diptericin by DIF' IEV:0003514. http://purl.obolibrary.org/obo/IEV_0000449 Negative regulation of Ras-Raf-MAPK signaling by spred (Drosophila) OBSOLETE: remap to 'Negative regulation of Ras-Raf-MAPK signaling by spred' IEV:0003544. http://purl.obolibrary.org/obo/IEV_0002643 Translation of attacin [Drosophila] OBSOLETE: remap to 'Translation of attacin' IEV:0003485. http://purl.obolibrary.org/obo/IEV_0002393 Binding of Relish and NF-kappaB binding sequence [Drosophila] OBSOLETE: remap to 'Binding of Relish and NF-kappaB binding sequence' IEV:0003468. http://purl.obolibrary.org/obo/IEV_0002354 Dissociation of Toll:dMyD88:Tube and Pelle [Drosophila] OBSOLETE: remap to 'Dissociation of Toll:MyD88:Tube and Pelle' IEV:0003530. http://purl.obolibrary.org/obo/IEV_0002688 suppression knockout Knocked out gene is the suppressor of a phenotype. OBSOLETE: remap to CV intraction type 'suppressive interaction' MI:0796 and genetic experimental form 'knock out' MI:0788. http://purl.obolibrary.org/obo/IEV_0003410 Cleavage of Spaetzle by serine protease [Drosophila] OBSOLETE: remap to 'Cleavage of Spaetzle by serine protease' IEV:0003502. http://purl.obolibrary.org/obo/IEV_0000117 Negative feedback regulation of Ras-Raf-MAPK signaling by spred (Drosophila) OBSOLETE: remap to 'Negative feedback regulation of Ras-Raf-MAPK signaling by spred' IEV:0003546. http://purl.obolibrary.org/obo/IEV_0002646 Translation of cecropin [Drosophila] OBSOLETE: remap to 'Translation of cecropin' IEV:0003486. http://purl.obolibrary.org/obo/IEV_0002380 Drosophila IMD pathway [Drosophila] OBSOLETE: remap to 'IMD signaling pathway' IEV:0003456. http://purl.obolibrary.org/obo/IEV_0002686 suppression underexpression Underexpression is the suppressor of a phenotype. OBSOLETE: remap to CV intraction type 'suppressive interaction' MI:0796 and genetic experimental form 'under expressed' MI:0223. http://purl.obolibrary.org/obo/IEV_0002394 Transcription of antimicrobial peptide by Relish [Drosophila] OBSOLETE: remap to 'Transcription of antimicrobial peptide by Relish' IEV:0003478. http://purl.obolibrary.org/obo/IEV_0001338 Flower formation The process that gives rise to the flower. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/IEV_0002388 Activation of TAK1 by IMD [Drosophila] OBSOLETE: remap to 'Activation of TAK1 by IMD' IEV:0003459. http://purl.obolibrary.org/obo/IEV_0000537 Interaction in nucleus OBSOLETE: remap to 'Unknown interaction' IEV:0000922. http://purl.obolibrary.org/obo/IEV_0002353 Autophosphorylation of Pelle [Drosophila] OBSOLETE: remap to 'Autophosphorylation of Pelle' IEV:0003493. http://purl.obolibrary.org/obo/IEV_0002389 Phosphorylation of DmIKK by TAK1 [Drosophila] OBSOLETE: remap to 'Phosphorylation of IKK complex by TAK1' IEV:0000784. http://purl.obolibrary.org/obo/IEV_0002642 Transcription of attacin by Relish [Drosophila] OBSOLETE: remap to 'Transcription of attacin by Relish' IEV:0003476. http://purl.obolibrary.org/obo/IEV_0002513 Regulation of Drosophila Toll receptor signaling OBSOLETE: remap to 'Regulation of Toll receptor signaling' IEV:0003569. http://purl.obolibrary.org/obo/IEV_0002267 Wnt signaling pathway (Xenopus) OBSOLETE: remap to 'Wnt signaling pathway' IEV:0000027. http://purl.obolibrary.org/obo/IEV_0003369 Expression of antimicrobial peptide by Dorsal [Drosophila] OBSOLETE: remap to 'Expression of antimicrobial peptide by Dorsal' IEV:0003533. http://purl.obolibrary.org/obo/IEV_0002375 DIF:Dorsal signaling [Drosophila] OBSOLETE: remap to 'DIF:Dorsal signaling' IEV:0003508. http://purl.obolibrary.org/obo/IEV_0000089 Negative regulation of osteoblast differentiation Any process that stops, prevents or reduces the rate, frequency or extent of osteoblast differentiation. http://purl.obolibrary.org/obo/IEV_0001196 Activation of Deltex [Drosophila] Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it may also act as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch. May function as an ubiquitin ligase protein in the Notch pathway. OBSOLETE: remap to 'Activation of Deltex' IEV:0003541. http://purl.obolibrary.org/obo/IEV_0000116 Negative feedback regulation of Ras-Raf-MAPK signaling by Sprouty (Drosophila) OBSOLETE: remap to 'Negative feedback regulation of Ras-Raf-MAPK signaling by Sprouty' IEV:0003547. http://purl.obolibrary.org/obo/IEV_0002340 Drosophila Toll-like receptor signaling OBSOLETE: remap to 'Toll receptor signaling' IEV:0003490. http://purl.obolibrary.org/obo/IEV_0001295 B cell receptor signaling (through Ras and ERK cascade) http://purl.obolibrary.org/obo/IEV_0000108 Toll-like receptor signaling pathway (p38 cascade) http://purl.obolibrary.org/obo/IEV_0000983 Permeabilization of mitochondria http://purl.obolibrary.org/obo/IEV_0001602 EndoG mediated signaling http://purl.obolibrary.org/obo/IEV_0000190 Induction of (Para) dormancy http://purl.obolibrary.org/obo/IEV_0001853 Positive regulation of (phosphorylation of Bad) in AKT(PKB)-Bad signaling http://purl.obolibrary.org/obo/IEV_0000482 CD4 T cell receptor signaling (through PLC gamma, calcineurin and NF-AT) http://purl.obolibrary.org/obo/IEV_0003160 2-(alpha-Hydroxyethyl)thiamine diphosphate + Enzyme N6-(lipoyl)lysine => TPP + [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine( EC:1.2.4.1 ) http://purl.obolibrary.org/obo/IEV_0000825 PDGF signaling pathway (through Grb2, Sos, Ras, PI3K, AKT and IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0000982 Oligomerization of Bak http://purl.obolibrary.org/obo/IEV_0001866 HDAC nuclear export signaling http://purl.obolibrary.org/obo/IEV_0000677 GDP-GTP exchange of small GTPase by GEF http://purl.obolibrary.org/obo/IEV_0002714 Toll-like receptor signaling pathway (through JNK cascade) http://purl.obolibrary.org/obo/IEV_0001200 Integrin signaling pathway (through PI3K, Vav and Rac) http://purl.obolibrary.org/obo/IEV_0000109 Negative regulation of BAD inactivation signaling http://purl.obolibrary.org/obo/IEV_0000168 Endodormancy http://purl.obolibrary.org/obo/IEV_0000280 CD4 T cell receptor signaling (through Ras and ERK cascade) http://purl.obolibrary.org/obo/IEV_0000540 Positive regulation of BAD inactivation signaling http://purl.obolibrary.org/obo/IEV_0000615 Integrin signaling pathway (through PI3K-AKT (PKB)-Bad signaling) http://purl.obolibrary.org/obo/IEV_0000618 Integrin signaling pathway (through Rac and JNK cascade) http://purl.obolibrary.org/obo/IEV_0000678 Binding of small GTPase-GTP and target protein http://purl.obolibrary.org/obo/IEV_0001277 Complex formation of IgM and Ig alpha:beta in plasma membrane http://purl.obolibrary.org/obo/IEV_0001595 Protein involved in DNA fragmentation and chromatin condensation signaling http://purl.obolibrary.org/obo/IEV_0001668 Relocation of free Bid to cytosol http://purl.obolibrary.org/obo/IEV_0001719 Nuclear import of HDAC5:importin alpha http://purl.obolibrary.org/obo/IEV_0001728 Phosphorylation of IKK alpha by AKT(PKB) http://purl.obolibrary.org/obo/IEV_0001803 Dephosphorylation of AKT(PKB) by PP2A http://purl.obolibrary.org/obo/IEV_0001906 Dissociation of calcium ion and cPKC http://purl.obolibrary.org/obo/IEV_0001907 Dissociation of DAG and cPKC http://purl.obolibrary.org/obo/IEV_0001917 Dissociation of DAG and PKC theta http://purl.obolibrary.org/obo/IEV_0001922 Dissociation of calcium ion and PKC http://purl.obolibrary.org/obo/IEV_0001923 Dissociation of DAG and PKC http://purl.obolibrary.org/obo/IEV_0001928 Negative feedback regulation of p53 degradation signaling http://purl.obolibrary.org/obo/IEV_0001995 Binding of G beta gamma and calcium ion channel http://purl.obolibrary.org/obo/IEV_0002027 Negative regulation of (Binding of GPCR and G alpha i) http://purl.obolibrary.org/obo/IEV_0002070 Binding of Rap1 and Crk http://purl.obolibrary.org/obo/IEV_0002180 TGF beta receptor complex degradation signaling http://purl.obolibrary.org/obo/IEV_0002214 Cell division within the secondary xylem http://purl.obolibrary.org/obo/IEV_0002215 Cell division within the vascular cambium http://purl.obolibrary.org/obo/IEV_0002216 Cell wall organization and biosynthesis http://purl.obolibrary.org/obo/IEV_0002218 Hemicellulose biosynthesis http://purl.obolibrary.org/obo/IEV_0002232 Ubiquitination of JAK by SOCS1 http://purl.obolibrary.org/obo/IEV_0002233 Proteasome degradation of JAK by 26S proteasome http://purl.obolibrary.org/obo/IEV_0002500 Ventral mesoderm specification http://purl.obolibrary.org/obo/IEV_0002529 Complex formation of integrin complex, caveolin, Fyn and Shc http://purl.obolibrary.org/obo/IEV_0002538 Mesoderm morphogenesis http://purl.obolibrary.org/obo/IEV_0002539 Wnt secretory pathway http://purl.obolibrary.org/obo/IEV_0002542 Signaling with Wnt http://purl.obolibrary.org/obo/IEV_0002543 Signaling without Wnt http://purl.obolibrary.org/obo/IEV_0002568 Notch secretory pathway http://purl.obolibrary.org/obo/IEV_0002596 Ci/Gli processing signaling http://purl.obolibrary.org/obo/IEV_0002613 Translocation from Golgi to cytosol http://purl.obolibrary.org/obo/IEV_0002801 Citric acid = cis-Aconitic acid + H2O( EC:4.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0002994 cis-Aconitic acid + H2O = Isocitric acid( EC:4.2.1.3 ) http://purl.obolibrary.org/obo/IEV_0003181 TPP + Pyruvic acid => 2-(alpha-Hydroxyethyl)thiamine diphosphate + CO2( EC:1.2.4.1 ) http://purl.obolibrary.org/obo/IEV_0003506 DIF signaling http://purl.obolibrary.org/obo/IEV_0003507 Dorsal signaling http://purl.obolibrary.org/obo/IEV_0003508 DIF:Dorsal signaling http://purl.obolibrary.org/obo/IEV_0003677 Binding of Melted and TSC1 in cytosol http://purl.obolibrary.org/obo/IEV_0000847 RTK signaling pathway (through Grb2, Sos, Ras, RalGDS, Ral, RalBP1 and Rac-GTP hydrolysis signaling) http://purl.obolibrary.org/obo/IEV_0000211 Release of (eco) dormancy http://purl.obolibrary.org/obo/IEV_0001849 Negative regulation of (dephosphorylation of AKT(PKB)) in negative regulation of AKT(PKB)-Bad signaling http://purl.obolibrary.org/obo/IEV_0001011 AIF mediated signaling http://purl.obolibrary.org/obo/IEV_0001235 TPO signaling pathway (through PI3K, PLCgamma and PKC) http://purl.obolibrary.org/obo/IEV_0001298 B cell receptor signaling (through IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0000538 Regulation of BAD inactivation signaling http://purl.obolibrary.org/obo/IEV_0000066 CD4 T cell receptor signaling (through PLC gamma, PKC and IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0000281 CD4 T cell receptor signaling (through Vav, Rac and JNK cascade) http://purl.obolibrary.org/obo/IEV_0000123 PDGF signaling pathway (through Grb2, Sos, Ras and Erk cascade) http://purl.obolibrary.org/obo/IEV_0001285 Binding of BLNK and BtK in cytosol http://purl.obolibrary.org/obo/IEV_0001994 Binding of G beta gamma and GRK2/3 http://purl.obolibrary.org/obo/IEV_0001996 Binding of G beta gamma and sodium ion channel http://purl.obolibrary.org/obo/IEV_0000172 Paradormancy http://purl.obolibrary.org/obo/IEV_0003857 L-Glutamine + H2O = L-Glutamate + NH3( EC:6.3.5.5 ) http://purl.obolibrary.org/obo/IEV_0001234 TPO signaling pathway (through Sos, Ras and Erk cascade) http://purl.obolibrary.org/obo/IEV_0000114 TNFR1 signaling pathway (through caspase cascade) http://purl.obolibrary.org/obo/IEV_0001294 B cell receptor signaling (through PLC gamma, calcineurin and NF-AT) http://purl.obolibrary.org/obo/IEV_0000856 RTK signaling pathway (through Grb2, Sos, Ras, RalGDS, Ral and PLD) http://purl.obolibrary.org/obo/IEV_0000616 Integrin signaling pathway (through Rho) http://purl.obolibrary.org/obo/IEV_0000802 TNFR2 signaling pathway (through IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0001857 Negative regulation of (phosphorylation of Bad) in AKT(PKB)-Bad signaling http://purl.obolibrary.org/obo/IEV_0001603 CAD signaling http://purl.obolibrary.org/obo/IEV_0000179 Binding of Cyt c and Bcl-2/Bcl-xL http://purl.obolibrary.org/obo/IEV_0000127 Integrin signaling pathway (through ERK cascade) http://purl.obolibrary.org/obo/IEV_0001999 Binding of G alpha i-GTP and PLC beta http://purl.obolibrary.org/obo/IEV_0000096 Ecodormancy http://purl.obolibrary.org/obo/IEV_0000000 Event http://purl.obolibrary.org/obo/IEV_0003057 3-Carboxy-1-hydroxypropyl-ThPP + Enzyme N6-(lipoyl)lysine = TPP + [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine( EC:1.2.4.2 ) http://purl.obolibrary.org/obo/IEV_0000239 Toll-like receptor signaling pathway (through LPS, TLR4, MyD88, IRAK-1, TAK1 and IKK-NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0001296 B cell receptor signaling (through Vav and Rac) http://purl.obolibrary.org/obo/IEV_0000113 TNFR1 signaling pathway (through NF-kappaB cascade) http://purl.obolibrary.org/obo/IEV_0002576 Secretory pathway of Hedgehog http://purl.obolibrary.org/obo/IEV_0002804 TPP + 2-Oxo-glutaric acid = 3-Carboxy-1-hydroxypropyl-ThPP + CO2( EC:1.2.4.2 ) http://purl.obolibrary.org/obo/IEV_0003858 2 ATP + HCO3- + NH3 = 2 ADP + Orthophosphate + Carbamoyl phosphate( EC:6.3.5.5 ) http://purl.obolibrary.org/obo/IEV_0000455 TNFR1 signaling pathway (through JNK cascade) http://purl.obolibrary.org/obo/iev#negatively_regulates negatively_regulates http://purl.obolibrary.org/obo/iev#regulates regulates http://purl.obolibrary.org/obo/iev#positively_regulates positively_regulates http://purl.obolibrary.org/obo/iev#regulates regulates http://purl.obolibrary.org/obo/iev#regulates regulates http://purl.obolibrary.org/obo/iev#part_of part of