Term IRI Term label Parent term IRI Parent term label Alternative term Definition
http://purl.obolibrary.org/obo/BFO_0000002 continuant http://purl.obolibrary.org/obo/BFO_0000001 entity endurant An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.
http://purl.obolibrary.org/obo/BFO_0000003 occurrent http://purl.obolibrary.org/obo/BFO_0000001 entity perdurant An entity that has temporal parts and that happens, unfolds or develops through time. Sometimes also called perdurants.
http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant substantial entity A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.
http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant http://purl.obolibrary.org/obo/BFO_0000005 dependent continuant trope A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.
http://purl.obolibrary.org/obo/IAO_0000009 data item label http://purl.obolibrary.org/obo/IAO_0000030 information content entity datum label An information content entity that is part of some data item and is used to partially define the denotation of that data item.
http://purl.obolibrary.org/obo/IAO_0000027 data item http://purl.obolibrary.org/obo/IAO_0000030 information content entity data An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method that reliably tends to produce (approximately) truthful statements.
http://purl.obolibrary.org/obo/IAO_0000109 measurement data item http://purl.obolibrary.org/obo/IAO_0000027 data item measurement datum A data item that is a recording of the output of an assay.
http://purl.obolibrary.org/obo/IAO_0000184 scatter plot http://purl.obolibrary.org/obo/IAO_0000038 graph scattergraph A scatterplot is a graph which uses Cartesian coordinates to display values for two variables for a set of data. The data is displayed as a collection of points, each having the value of one variable determining the position on the horizontal axis and the value of the other variable determining the position on the vertical axis.
http://purl.obolibrary.org/obo/IAO_0000300 textual entity http://purl.obolibrary.org/obo/IAO_0000030 information content entity text A textual entity is a part of a manifestation (FRBR sense), a generically dependent continuant whose concretizations are patterns of glyphs intended to be interpreted as words, formulas, etc.
http://purl.obolibrary.org/obo/IAO_0000577 CRID http://purl.obolibrary.org/obo/IAO_0000028 symbol centrally registered identifier A symbol that is sufficient to look up information about the corresponding entity from its CRID (centrally registered identifier) registry.
http://purl.obolibrary.org/obo/IAO_0000578 centrally registered identifier http://purl.obolibrary.org/obo/IAO_0000030 information content entity Centrally Registered IDentifier (CRID) An information content entity that consists of a CRID symbol and additional information about which CRID registry it belongs.
http://purl.obolibrary.org/obo/IAO_0000579 CRID registry http://purl.obolibrary.org/obo/IAO_0000100 data set centrally registered identifier registry A data set that consists of CRIDs (centrally registered identifier) and additional information about their corresponding entities, that were recorded in the dataset through an assigning a centrally registered identifier process.
http://purl.obolibrary.org/obo/IAO_0000584 time sampled measurement data set http://purl.obolibrary.org/obo/IAO_0000100 data set experimental time series A data set that is an aggregate of data recording some measurement at a number of time points. The time series data set is an ordered list of pairs of time measurement data and the corresponding measurement data acquired at that time.
http://purl.obolibrary.org/obo/OBI_0000070 assay http://purl.obolibrary.org/obo/OBI_0000011 planned process scientific observation A planned process with the objective to produce information about the material entity that is the evaluant, by physically examining it or its proxies.
http://purl.obolibrary.org/obo/OBI_0000086 reagent role http://purl.obolibrary.org/obo/BFO_0000023 role reagent A role inhering in a biological or chemical entity that is intended to be applied in a scientific technique to participate (or have molecular components that participate) in a chemical reaction that facilitates the generation of data about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer.
http://purl.obolibrary.org/obo/OBI_0000094 material processing http://purl.obolibrary.org/obo/OBI_0000011 planned process material transformation A planned process which results in physical changes in a specified input material
http://purl.obolibrary.org/obo/OBI_0000250 dye role http://purl.obolibrary.org/obo/REO_0000171 molecular label role dye A molecular label role which inheres in a material entity and which is realized in the process of detecting a molecular dye that imparts color to some material of interest.
http://purl.obolibrary.org/obo/OBI_0000423 extract http://purl.obolibrary.org/obo/OBI_0000047 processed material extracted material an extract is a material entity which results from an extraction process
http://purl.obolibrary.org/obo/OBI_0000424 transcription profiling assay http://purl.obolibrary.org/obo/OBI_0000443 analyte assay gene expression profiling An assay which aims to provide information about gene expression and transcription activity using ribonucleic acids collected from a material entity using a range of techniques and instrument such as DNA sequencers, DNA microarrays, Northern Blot
http://purl.obolibrary.org/obo/OBI_0000456 material transformation objective http://purl.obolibrary.org/obo/IAO_0000005 objective specification artifact creation objective an objective specifiction that creates an specific output object from input materials.
http://purl.obolibrary.org/obo/OBI_0000674 center value http://purl.obolibrary.org/obo/STATO_0000152 quartile second quartile [STATO Definition]
The median is that value of the variate which divides the total frequency into two halves.
The median is measure of central tendency of data. It is obtained by arranging the observations in order from smallest to largest value. If there is an odd number of observations, the median is the middle value. If there is an even number of observations, the median is the average of the two middle values.
http://purl.obolibrary.org/obo/OBI_0000675 statistical hypothesis test objective http://purl.obolibrary.org/obo/OBI_0200166 data transformation objective hypothesis test objective is a data transformation objective where the aim is to estimate statistical significance with the aim of proving or disproving a hypothesis by means of some data transformation
http://purl.obolibrary.org/obo/OBI_0000679 average value http://purl.obolibrary.org/obo/STATO_0000029 measure of central tendency arithmetic mean [STATO definition]:
The arithmetic mean is defined as the sum of the numerical values of each and every observation divided by the total number of observations. S The arithmetic mean A is defined by the formula
A=sum[Ai] / n where i ranges from 1 to n and Ai represents the value of individual observations.
The arithmetic mean is significantly affected by extreme values and outliers. A better measure of central tendency is the median (http://purl.obolibrary.org/obo/OBI_0000674).
http://purl.obolibrary.org/obo/OBI_0000722 paired-end library http://purl.obolibrary.org/obo/OBI_0000047 processed material paired-end tag (PET) library is a collection of short paired tags from the two ends of DNA fragments are extracted and covalently linked as ditag constructs
http://purl.obolibrary.org/obo/OBI_0000736 single fragment library http://purl.obolibrary.org/obo/OBI_0000047 processed material fragment library is a collection of short tags from DNA fragments, are extracted and covalently linked as single tag constructs
http://purl.obolibrary.org/obo/OBI_0000739 Student's t-test http://purl.obolibrary.org/obo/OBI_0000673 statistical hypothesis test t-test Studen't t-test is a data transformation with the objective of a statistical hypothesis test in which the test statistic has a Student's t distribution if the null hypothesis is true. It is applied when the population is assumed to be normally distributed but the sample sizes are small enough that the statistic on which inference is based is not normally distributed because it relies on an uncertain estimate of standard deviation rather than on a precisely known value.
http://purl.obolibrary.org/obo/OBI_0000747 material sample http://purl.obolibrary.org/obo/OBI_0100051 specimen sample population A material entity that has the material sample role
http://purl.obolibrary.org/obo/OBI_0000750 study design independent variable http://purl.obolibrary.org/obo/STATO_0000258 variable independent variable a directive information entity that is part of a study design. Independent variables are entities whose values are selected to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled
http://purl.obolibrary.org/obo/OBI_0000751 study design dependent variable http://purl.obolibrary.org/obo/STATO_0000258 variable dependent variable PRS-AGB: a dependent variable is a variable which assumes only values set by the operator according to a plan and are expected to influence the ranges of values assumed by a response variable aka independent variable.
http://purl.obolibrary.org/obo/OBI_0000791 multiple testing correction objective http://purl.obolibrary.org/obo/OBI_0200186 error correction objective multiple comparison correction objective A multiple testing correction objectives is a data transformation objective where the aim is to correct for a set of statistical inferences considered simultaneously
http://purl.obolibrary.org/obo/OBI_0000938 categorical measurement datum http://purl.obolibrary.org/obo/IAO_0000109 measurement data item nominal mesurement datum A measurement datum that is reported on a categorical scale
http://purl.obolibrary.org/obo/OBI_0000968 device http://purl.obolibrary.org/obo/OBI_0000047 processed material instrument A material entity that is designed to perform a function in a scientific investigation, but is not a reagent.
http://purl.obolibrary.org/obo/OBI_0001143 labeled nucleic acid extract http://purl.obolibrary.org/obo/OBI_0000924 labeled specimen labeled extract a labeled specimen that is the output of a labeling process and has grain labeled nucleic acid for detection of the nucleic acid in future experiments.
http://purl.obolibrary.org/obo/OBI_0001271 RNA-seq assay http://purl.obolibrary.org/obo/OBI_0600047 sequencing assay transcription profiling by high throughput sequencing An assay in which sequencing technology (e.g. Solexa/454) is used to generate RNA sequence, analyse the transcibed regions of the genome, and or to quantitate transcript abundance
http://purl.obolibrary.org/obo/OBI_0001755 selection criterion http://purl.obolibrary.org/obo/IAO_0000033 directive information entity selection rule A directive information entity which defines and states a principle of standard by which selection process may take place.
http://purl.obolibrary.org/obo/OBI_0100060 cultured cell population http://purl.obolibrary.org/obo/OBI_0000047 processed material cell culture sample A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history.
http://purl.obolibrary.org/obo/OBI_0200000 data transformation http://purl.obolibrary.org/obo/OBI_0000011 planned process data processing A planned process that produces output data from input data.
http://purl.obolibrary.org/obo/OBI_0200073 family wise error rate correction method http://purl.obolibrary.org/obo/OBI_0200089 multiple testing correction method FWER correction A family wise error rate correction method is a multiple testing procedure that controls the probability of at least one false positive.
http://purl.obolibrary.org/obo/OBI_0200083 survival analysis objective http://purl.obolibrary.org/obo/OBI_0200166 data transformation objective survival analysis A data transformation objective which has the data transformation aims to model time to event data (where events are e.g. death and or disease recurrence); the purpose of survival analysis is to model the underlying distribution of event times and to assess the dependence of the event time on other explanatory variables
http://purl.obolibrary.org/obo/OBI_0200089 multiple testing correction method http://purl.obolibrary.org/obo/OBI_0000668 error correction data transformation multiple testing procedure A multiple testing correction method is a hypothesis test performed simultaneously on M > 1 hypotheses. Multiple testing procedures produce a set of rejected hypotheses that is an estimate for the set of false null hypotheses while controlling for a suitably define Type I error rate
http://purl.obolibrary.org/obo/OBI_0200111 data visualization http://purl.obolibrary.org/obo/OBI_0000011 planned process visualization An planned process that creates images, diagrams or animations from the input data.
http://purl.obolibrary.org/obo/OBI_0200163 false discovery rate correction method http://purl.obolibrary.org/obo/OBI_0200089 multiple testing correction method FDR correction method The false discovery rate is a data transformation used in multiple hypothesis testing to correct for multiple comparisons. It controls the expected proportion of incorrectly rejected null hypotheses (type I errors) in a list of rejected hypotheses. It is a less conservative comparison procedure with greater power than familywise error rate (FWER) control, at a cost of increasing the likelihood of obtaining type I errors. .
http://purl.obolibrary.org/obo/OBI_0200201 ANOVA http://purl.obolibrary.org/obo/STATO_0000279 between group comparison statistical test Analysis of Variance ANalysis Of VAriance (ANOVA) is a data transformation in which a statistical test is performed to evaluate the null hypothesis that the means computed over the different groups as specified by the investigator do not differ. The test compares an F-statistics (a ratio of means) to an F-distribution and produces a p-value, used to reject or accept the null hypothesis given a false positive rate. The test assumes normality and equivariance of the data.
http://purl.obolibrary.org/obo/OBI_0400043 flow cell http://purl.obolibrary.org/obo/OBI_0000967 container flow_cell Aparatus in the fluidic subsystem where the sheath and sample meet. Can be one of several types; jet-in-air, quartz cuvette, or a hybrid of the two. The sample flows through the center of a fluid column of sheath fluid in the flow cell.
http://purl.obolibrary.org/obo/OBI_0400148 DNA microarray http://purl.obolibrary.org/obo/OBI_0400147 microarray DNA-array A DNA-microarray is a microarray that is used as a physical 2D immobilisation matrix for DNA sequences. DNA microarray-bound DNA fragments are used as targets for a hybridising probed sample.
http://purl.obolibrary.org/obo/OBI_0500000 study design http://purl.obolibrary.org/obo/IAO_0000104 plan specification experimental design A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution.
http://purl.obolibrary.org/obo/OBI_0500006 parallel group design http://purl.obolibrary.org/obo/OBI_0500000 study design independent measure design A parallel group design or independent measure design is a study design which uses unique experimental unit each experimental group, in other word no two individuals are shared between experimental groups, hence also known as parallel group design. Subjects of a treatment group receive a unique combination of independent variable values making up a treatment
http://purl.obolibrary.org/obo/OBI_0600015 group assignment http://purl.obolibrary.org/obo/OBI_0000011 planned process study assignment group assignment is a process which has an organism as specified input and during which a role is assigned
http://purl.obolibrary.org/obo/OBI_0600038 addition of molecular label http://purl.obolibrary.org/obo/OBI_0000094 material processing labeling a material processing technique intended to add a molecular label to some input material entity, to allow detection of the molecular target of this label in a detection of molecular label assay
http://purl.obolibrary.org/obo/OBI_0600064 recombinant vector cloning http://purl.obolibrary.org/obo/OBI_0000274 adding a material entity into a target molecular cloning a planned process with the objective to insert genetic material into a cloning vector for future replication of the inserted material
http://purl.obolibrary.org/obo/OBI_1000029 phage display library http://purl.obolibrary.org/obo/OBI_0000731 recombinant vector display library a phage display library is a collection of materials in which a mixture of genes or gene fragments is expressed and can be individually selected and amplified.
http://purl.obolibrary.org/obo/REO_0000171 molecular label role http://purl.obolibrary.org/obo/BFO_0000023 role molecular tracer role a reagent role inhering in a molecular entity intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay.
http://purl.obolibrary.org/obo/REO_0000280 molecular label http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity molecular tracer a molecular reagent intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay
http://purl.obolibrary.org/obo/SO_0000001 region http://purl.obolibrary.org/obo/BFO_0000031 generically dependent continuant sequence A sequence_feature with an extent greater than zero. A nucleotide region is composed of bases and a polypeptide region is composed of amino acids.
http://purl.obolibrary.org/obo/STATO_0000023 studentized range distribution http://purl.obolibrary.org/obo/STATO_0000067 continuous probability distribution q distribution The studentized range (q) distribution is a probability distribution used by the Tukey Honestly Significant Difference test.
The distribution of the statistic
[x̄(k)- x̄(1)]/(s/√n)
where random samples of size n have been taken from k independent and identically distributed normal populations, with x̄(1) and x̄(k) being, respectively, the smallest and largest of the k sample means, and s2 being the pooled estimate of the common variance. This statistic is particularly used in multiple comparison tests.
http://purl.obolibrary.org/obo/STATO_0000040 MA plot http://purl.obolibrary.org/obo/IAO_0000184 scatter plot M vs A plot an MA plot is a scatter plot of the log intensity ratios M = log_2(T/R) versus the average log intensities A = log_2(T*T)/2, where T and R represent the signal intensities in the test and reference channels respectively.
http://purl.obolibrary.org/obo/STATO_0000243 box and whisker plot http://purl.obolibrary.org/obo/IAO_0000038 graph box plot a box plot is a graph which plots datasets relying on their quartiles and the interquartile range to create the box and the whiskers
http://purl.obolibrary.org/obo/STATO_0000283 negative binomial distribution http://purl.obolibrary.org/obo/STATO_0000117 discrete probability distribution Pólya distribution negative binomial probability distribution is a discrete probability distribution of the number of successes in a sequence of Bernoulli trials before a specified (non-random) number of failures (denoted r) occur.
The negative binomial distribution, also known as the Pascal distribution or Pólya distribution, gives the probability of r-1 successes and x failures in x+r-1 trials, and success on the (x+r)th trial.
http://purl.obolibrary.org/obo/CHEBI_33839 macromolecule http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity polymer A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
http://purl.obolibrary.org/obo/STATO_0000134 true negative rate http://purl.obolibrary.org/obo/STATO_0000184 ratio specificity specificity is a measurement datum qualifying a binary classification test and is computed by substracting the false positive rate to the integral numeral 1
http://purl.obolibrary.org/obo/STATO_0000190 threshold cycle http://purl.obolibrary.org/obo/STATO_0000232 number of PCR cycle Ct Threshold cycle (or Ct or Cq) is a count which is defined as the fractional PCR cycle number at which the reporter fluorescence is greater than the threshold in the context of the RT-qPCR assay. The Ct is a basic principle of real time PCR and is an essential component in producing accurate and reproducible data.
http://purl.obolibrary.org/obo/STATO_0000221 random variable http://purl.obolibrary.org/obo/STATO_0000258 variable stochastic variable a random variable (or aleatory variable or stochastic variable) in probability and statistics, is a variable whose value is subject to variations due to chance (i.e. randomness, in a mathematical sense)
http://purl.obolibrary.org/obo/STATO_0000228 ordinal variable http://purl.obolibrary.org/obo/STATO_0000252 categorical variable ranked variable ordinal variable is a categorical variable where the discrete possible values are ordered or correspond to an implicit ranking
http://purl.obolibrary.org/obo/STATO_0000233 true positive rate http://purl.obolibrary.org/obo/STATO_0000184 ratio sensitivity sensitivity is a measurement datum qualifying a binary classification test and is computed by substracting the false negative rate to the integral numeral 1
http://purl.obolibrary.org/obo/STATO_0000252 categorical variable http://purl.obolibrary.org/obo/STATO_0000258 variable qualitative factor a categorical variable is a variable which that can only assume a finite number of value and cast observation in a small number of categories
http://purl.obolibrary.org/obo/STATO_0000011 cartesian coordinate axis http://purl.obolibrary.org/obo/STATO_0000007 axis rectangular coordinate axis a cartesian axis is one of 3 the axis in a cartesian coordinate system defining a referential in 3 dimensions. each of the axis is orthogonal to the other 2
http://purl.obolibrary.org/obo/STATO_0000027 test of association between categorical variables http://purl.obolibrary.org/obo/OBI_0000673 statistical hypothesis test test of association linkage between 2 categorical variable test is a statistical test which evaluates if there is an association between a predictor variable assuming discrete values and a response variable also assuming discrete values
http://purl.obolibrary.org/obo/STATO_0000037 standard error of the mean http://purl.obolibrary.org/obo/IAO_0000109 measurement data item SEM The standard error of the mean (SEM) is data item denoting the standard deviation of the sample-mean's estimate of a population mean.
It is calculated by dividing the sample standard deviation (i.e., the sample-based estimate of the standard deviation of the population) by the square root of n , the size (number of observations) of the sample.
http://purl.obolibrary.org/obo/STATO_0000044 one-way ANOVA http://purl.obolibrary.org/obo/OBI_0200201 ANOVA one factor ANOVA one-way anova is an analysis of variance where the different groups being compared are associated with the factor levels of only one independent variable. The null hypothesis is an absence of difference between the means calculated for each of the groups. The test assumes normality and equivariance of the data.
http://purl.obolibrary.org/obo/STATO_0000045 two-way ANOVA http://purl.obolibrary.org/obo/OBI_0200201 ANOVA two factor ANOVA two-way anova is an analysis of variance where the different groups being compared are associated the factor levels of exatly 2 independent variables. The null hypothesis is an absence of difference between the means calculated for each of the groups. The test assumes normality and equivariance of the data.
http://purl.obolibrary.org/obo/STATO_0000054 homoskedasticity hypothesis http://purl.obolibrary.org/obo/STATO_0000065 hypothesis equality of variance homoskedasticity is a null hypothesis stating that all variances under consideration are homogenous
http://purl.obolibrary.org/obo/STATO_0000076 Mann-Whitney U-test http://purl.obolibrary.org/obo/STATO_0000198 non-parametric test rank-sum test for the comparison of two samples The Mann-Whitney U-test is a null hypothesis statistical testing procedure which allows two groups (or conditions or treatments) to be compared without making the assumption that values are normally distributed.
The Mann-Whitney test is the non-parametric equivalent of the t-test for independent samples
http://purl.obolibrary.org/obo/STATO_0000077 Shapiro-Wilk test http://purl.obolibrary.org/obo/STATO_0000191 goodness of fit statistical test S-W test Shapiro-Wilk test is a goodness of fit test which evaluates the null hypothesis that the sample is drawn from a population following a normal distribution
http://purl.obolibrary.org/obo/STATO_0000081 Pearson's Chi square test of independence between categorical variables http://purl.obolibrary.org/obo/STATO_0000027 test of association between categorical variables Chi2 test for independence Pearson's Chi-Squared test is a statistical null hypothesis test which is used to either evaluate goodness of fit of dataset to a Chi-Squared distribution or used to test independence of 2 categorical variables (ie absence of association between those variables).
http://purl.obolibrary.org/obo/STATO_0000083 Kolmogorov-Smirnov test http://purl.obolibrary.org/obo/STATO_0000191 goodness of fit statistical test K-S test Kolmogorov-Smirnov test is a goodness of fit test which evaluates the null hypothesis that a sample is drawn from a population that follows a specific continuous probability distribution.
http://purl.obolibrary.org/obo/STATO_0000094 Kruskal Wallis test http://purl.obolibrary.org/obo/STATO_0000198 non-parametric test rank-sum test for the comparison of multiple (more than 2) samples The Kruskal–Wallis test is a null hypothesis statistical testing objective which allows multiple (n>=2) groups (or conditions or treatments) to be compared, without making the assumption that values are normally distributed. The Kruskal–Wallis test is the non-parametric equivalent of the independent samples ANOVA
The Kruskal–Wallis test is most commonly used when there is one nominal variable and one measurement variable, and the measurement variable does not meet the normality assumption of an anova.
http://purl.obolibrary.org/obo/STATO_0000099 random effects model http://purl.obolibrary.org/obo/STATO_0000107 statistical model variance components model a random effect(s) model, also called a variance components model, is a kind of hierarchical linear model. It assumes that the dataset being analysed consists of a hierarchy of different populations whose differences relate to that hierarchy.
http://purl.obolibrary.org/obo/STATO_0000100 standardized mean difference http://purl.obolibrary.org/obo/STATO_0000085 effect size estimate SMD standardized mean difference is data item computed by forming the difference between two means, divided by an estimate of the within-group standard deviation.
It is used to provide an estimatation of the effect size between two treatments when the predictor (independent variable) is categorical and the response(dependent) variable is continuous
http://purl.obolibrary.org/obo/STATO_0000113 variance http://purl.obolibrary.org/obo/STATO_0000028 measure of variation σ2 variance is a data item about a random variable or probability distribution. it is equivalent to the square of the standard deviation. It is one of several descriptors of a probability distribution, describing how far the numbers lie from the mean (expected value).The variance is the second moment of a distribution.
http://purl.obolibrary.org/obo/STATO_0000127 99% confidence interval http://purl.obolibrary.org/obo/STATO_0000196 confidence interval confidence interval at 1% of type I error rate a confidence interval which covers 99% of the sampling distribution, meaning that there is a 1% risk of false positive (type I error)
http://purl.obolibrary.org/obo/STATO_0000133 post-hoc analysis http://purl.obolibrary.org/obo/STATO_0000279 between group comparison statistical test a posteriori test A post-hoc analysis is a statistical test carried out following an analysis of variance which ruled out the null hypothesis of absence of difference between group which allows identifying which groups differ.
http://purl.obolibrary.org/obo/STATO_0000148 Cochran-Armitage test for trend http://purl.obolibrary.org/obo/STATO_0000027 test of association between categorical variables CATT The Cochran-Armitage test is a statistical test used in categorical data analysis when the aim is to assess for the presence of an association between a dichotomous variable (variable with two categories) and a polychotomous variable (a variable with k categories).
The two-level variable represents the response, and the other represents an explanatory variable with ordered levels. The null hypothesis is the hypothesis of no trend, which means that the binomial proportion is the same for all levels of the explanatory variable
For example, doses of a treatment can be ordered as 'low', 'medium', and 'high', and we may suspect that the treatment benefit cannot become smaller as the dose increases. The trend test is often used as a genotype-based test for case-control genetic association studies.
http://purl.obolibrary.org/obo/STATO_0000172 fragments per kilobase of transcript per million fragments mapped http://purl.obolibrary.org/obo/STATO_0000047 count FPKM expected fragments per kilobase of transcript per million fragments mapped is a metric used to report transcript expression event as generated by RNA-Seq using paired-end library. The calculated value results from 2 types of normalization, one to take into account the difference in reads counts associated with transcript length (at equal abundance, longer transcripts will have more reads than shorter transcripts) , (hence the 'per kilobase of transcript') and the other one to take into account different sequencing depth during distinct sequencing runs (hence the 'per millions mapped fragment'. The metric is specifically produced by cufflink software.
http://purl.obolibrary.org/obo/STATO_0000201 Spearman's rank correlation coefficient http://purl.obolibrary.org/obo/STATO_0000142 correlation coefficient Spearman's rho Spearman's rank correlation coefficient is a correlation coefficient which is a nonparametric measure of statistical dependence between two ranked variables. It assesses how well the relationship between two variables can be described using a monotonic function. If there are no repeated data values, a perfect Spearman correlation of +1 or −1 occurs when each of the variables is a perfect monotone function of the other.
Spearman's coefficient may be used when the conditions for computing Pearson's correlation are not met (e.g linearity, normality of the 2 continuous variables) but may require a ranking transformation of the variables
http://purl.obolibrary.org/obo/STATO_0000204 F-distribution http://purl.obolibrary.org/obo/STATO_0000067 continuous probability distribution Snedecor Fisher distribution the F-distribution is a continuous probability distribution which arises in the testing of whether two observed samples have the same variance.
http://purl.obolibrary.org/obo/STATO_0000206 reads per kilobase of transcript per million fragments mapped http://purl.obolibrary.org/obo/STATO_0000047 count RPKM RPKM is a kind of count which numbers the sequence reads found per kilobase of transcript reported to million of sequence reads. RPKM is a metric generated by ERANGE software tool as reported by Mortazi et al, in 2008.
The metric has been enhanced and replaced by FPKM to better take into account splice variant. FKPM uses a statistical model to perform the computation.
http://purl.obolibrary.org/obo/STATO_0000214 50% confidence interval http://purl.obolibrary.org/obo/STATO_0000196 confidence interval confidence interval at 10% of type I error rate a confidence interval which covers 50% of the sampling distribution, meaning that there is a 50% risk of false positive (type I error)
http://purl.obolibrary.org/obo/STATO_0000226 equal variance testing objective http://purl.obolibrary.org/obo/OBI_0000675 statistical hypothesis test objective homoschedacity testing objective It is a testing objective to ensure the variances of the different groups used in a statistical test are similar (i.e. not too different).
http://purl.obolibrary.org/obo/STATO_0000227 normal distribution http://purl.obolibrary.org/obo/STATO_0000329 symmetric distribution Gaussian distribution a normal distribution is a continuous probability distribution described by a probability distribution function described here:
http://mathworld.wolfram.com/NormalDistribution.html
http://purl.obolibrary.org/obo/STATO_0000230 expected value http://purl.obolibrary.org/obo/IAO_0000109 measurement data item μ the expected value (or expectation, mathematical expectation, EV, mean, or the first moment) of a random variable is a data item which corresponds to the weighted average of all possible values that this random variable can take on. The weights used in computing this average correspond to the probabilities in case of a discrete random variable, or densities in case of a continuous random variable. From a rigorous theoretical standpoint, the expected value is the integral of the random variable with respect to its probability measure.
http://purl.obolibrary.org/obo/STATO_0000231 95% confidence interval http://purl.obolibrary.org/obo/STATO_0000196 confidence interval confidence interval at 5% of type I error rate a confidence interval which covers 95% of the sampling distribution, meaning that there is a 5% risk of false positive (type I error). If the number of observations made is large enough, the sampling distribution can be assumed to be normal, which entails that 95% of the sampling distributions falls within roughly2 (1.96) standard deviations from the mean.
http://purl.obolibrary.org/obo/STATO_0000237 standard deviation http://purl.obolibrary.org/obo/STATO_0000028 measure of variation σ The standard deviation of a random variable, statistical population, data set, or probability distribution is a measure of variation which correspond to the average distance from the mean of the data set to any given point of that dataset. It also corresponds to the square root of its variance.
http://purl.obolibrary.org/obo/STATO_0000238 high-content screening http://purl.obolibrary.org/obo/STATO_0000239 high throughput screening high throughput screening high content screening is a kind of investigation which uses a standardized cellular assays to test the effect of substances (RNAi or small molecules) held in libraries on a cellular phenotype. it relies on microscopy imaging and or flow-cytometry, robotic handling to ensure fast and high-throughput.
http://purl.obolibrary.org/obo/STATO_0000240 Kendall's correlation coefficient http://purl.obolibrary.org/obo/STATO_0000142 correlation coefficient Kendall's tau (τ) coefficient Kendall's correlation coefficient is a correlation coefficient between 2 ordinal variables (natively or following a ranking procedure) and may be used when the conditions for computing Pearson's correlation are not met (e.g linearity, normality of the 2 continuous variables)
http://purl.obolibrary.org/obo/STATO_0000245 relative risk http://purl.obolibrary.org/obo/STATO_0000085 effect size estimate risk ratio Relative risk is a measurement datum which denotes the risk of an 'event' relative to an 'exposure'. Relative risk is calculated by forming the ratio of the probability of the event occurring in the exposed group versus the probability of this event occurring in the non-exposed group.
http://purl.obolibrary.org/obo/STATO_0000248 blocking variable http://purl.obolibrary.org/obo/STATO_0000258 variable nuisance variable a blocking variable is a independent variable which is used in a blocking process part of an experiment with the purpose of maximizing the signal coming from the main variable.
http://purl.obolibrary.org/obo/STATO_0000260 repeated measure ANOVA http://purl.obolibrary.org/obo/STATO_0000202 within subject comparison statistical test ANOVA for correlated samples repeated measure ANOVA is a kind of ANOVA specifically developed for non-independent observations as found when repeated measurements on the sample experimental unit.
repeated measure ANOVA is sensitive to departure from normality (evaluation using Bartlett's test), more so in the case of unbalanced groups (i.e. different sizes of sample populations).
Departure from sphericity (evaluation using Mauchly'test) used to be an issue which is now handled robustly by modern tools such as R's lme4 or nlme, which accommodate dependence assumptions other than sphericity.
http://purl.obolibrary.org/obo/STATO_0000264 factor level combination http://purl.obolibrary.org/obo/IAO_0000100 data set treatment combination a factor level combination is one a possible sets of factor levels resulting from the cartesian product of sets of factor and their levels as defined in a factorial design
http://purl.obolibrary.org/obo/STATO_0000265 factor level http://purl.obolibrary.org/obo/IAO_0000027 data item treatment A factor level is data item which corresponds to one of the value assumed by a factor or independent variable manipulated and set by the experimentalist. In the context of factorial design, a factor level is assumed to be or treated as a category in a categorical variable
http://purl.obolibrary.org/obo/STATO_0000275 transmission disequilibrium test http://purl.obolibrary.org/obo/STATO_0000027 test of association between categorical variables TDT The transmission disequilibrium test is a statistical test for genetic linkage between genetic marker and a trait in families. The test is robust to population structure.
http://purl.obolibrary.org/obo/STATO_0000280 Pearson's correlation coefficient http://purl.obolibrary.org/obo/STATO_0000142 correlation coefficient r statistics The Pearson's correlation coefficient is a correlation coefficient which evaluates two continuous variables for association strength in a data sample. It assumes that both variables are normally distributed and linearity exists.
The coefficient is calculated by dividing their covariance with the product of their individual standard deviations. It is a normalized measurement of how the two are linearly related.
http://purl.obolibrary.org/obo/STATO_0000286 one tailed test http://purl.obolibrary.org/obo/OBI_0200000 data transformation one sided test a one-tailed test is a statistical test which, assuming an unskewed probability distribution, allocates all of the significance level to evaluate only one hypothesis to explain a difference.
The one-tailed test provides more power to detect an effect in one direction by not testing the effect in the other direction.
one-tailed test should be preceded by two-tailed test in order to avoid missing out on detecting alternate effect explaining an observed difference.
http://purl.obolibrary.org/obo/STATO_0000289 design matrix http://purl.obolibrary.org/obo/IAO_0000030 information content entity model matrix a design matrix is an information content entity which denotes a study design. The design matrix is a n by m matrix where n the number of rows, corresponds to the number of observations (4 rows if quadruplicates) and where m, the number of columns corresponds to the number of independent variables. Each element in the matrix correspond to a discretized value representing one of the factor levels for a given factor.
A design matrix can be used as input to statistical modeling or statistical analysis.
The design matrix contains data on the independent variables (also called explanatory variables) in statistical models which attempt to explain observed data on a response variable (often called a dependent variable) in terms of the explanatory variables. The theory relating to such models makes substantial use of matrix manipulations involving the design matrix: see for example linear regression. A notable feature of the concept of a design matrix is that it is able to represent a number of different experimental designs and statistical models, e.g., ANOVA, ANCOVA, and linear regression
http://purl.obolibrary.org/obo/STATO_0000296 absence of enrichment hypothesis http://purl.obolibrary.org/obo/STATO_0000295 absence of positive difference hypothesis absence of over representation hypothesis absence of depletion difference hypothesis is a hypothesis which assumes that the representation of an element significantly greater than a threshold does not exist.
http://purl.obolibrary.org/obo/STATO_0000297 absence of depletion hypothesis http://purl.obolibrary.org/obo/STATO_0000294 absence of negative difference hypothesis absence of under representation hypothesis absence of depletion difference hypothesis is a hypothesis which assumes that the representation of an element significantly less than a threshold does not exist.
http://purl.obolibrary.org/obo/STATO_0000303 two sample t-test with equal variance http://purl.obolibrary.org/obo/STATO_0000279 between group comparison statistical test two sample t-test two sample t-test is a null hypothesis statistical test which is used to reject or accept the hypothesis of absence of difference between the means over 2 randomly sampled populations.
It uses a t-distribution for the test and assumes that the variables in the population are normally distributed and with equal variances.
http://purl.obolibrary.org/obo/STATO_0000304 two sample t-test with unequal variance http://purl.obolibrary.org/obo/STATO_0000279 between group comparison statistical test Welsh t-test Welch t-test is a two sample t-test used when the variances of the 2 populations/samples are thought to be unequal (homoskedasticity hypothesis not verified). In this version of the two-sample t-test, the denominator used to form the t-statistics, does not rely on a 'pooled variance' estimate.
http://purl.obolibrary.org/obo/STATO_0000309 Pearson's Chi square test of goodness of fit http://purl.obolibrary.org/obo/STATO_0000191 goodness of fit statistical test Chi2 test for goodness of fit Pearson's Chi-Squared test for goodnes of fit is a statistical null hypothesis test which is used to either evaluate goodness of fit of dataset to a Chi-Squared distribution
http://purl.obolibrary.org/obo/STATO_0000316 root-mean-square standardized effect http://purl.obolibrary.org/obo/STATO_0000085 effect size estimate Ψ root-mean-square standardized effect is a data item which denotes effect size in the context of analysis of variance and corresponds to the square root of the arithmetic average of p standardized effects (effects normalized to be expressed in standard deviation units).
http://purl.obolibrary.org/obo/STATO_0000347 Matern function anisotropic covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure
http://purl.obolibrary.org/obo/STATO_0000348 rational quadratic anisotropic covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure
http://purl.obolibrary.org/obo/STATO_0000349 spatial linear geometric anisotropic covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure SP(LINGA)
http://purl.obolibrary.org/obo/STATO_0000350 spatial spherical geometric anisotropic covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure SP(SPHGA)
http://purl.obolibrary.org/obo/STATO_0000351 spatial gaussian geometric anisotropic covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure SP(GAUGA)
http://purl.obolibrary.org/obo/STATO_0000352 spatial exponential geometric anisotropic covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure SP(EXPGA)
http://purl.obolibrary.org/obo/STATO_0000353 spatial exponential anisotropic covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure SP(EXPA)(c-list)
http://purl.obolibrary.org/obo/STATO_0000354 banded heterogeneous Toeplitz covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure TOEPH(q)
http://purl.obolibrary.org/obo/STATO_0000355 heterogeneous Toeplitz covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure TOEPH
http://purl.obolibrary.org/obo/STATO_0000356 banded Toeplitz covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure TOEP(q)
http://purl.obolibrary.org/obo/STATO_0000357 Toeplitz covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure TOEP
http://purl.obolibrary.org/obo/STATO_0000358 Huynh-Feldt covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure HF
http://purl.obolibrary.org/obo/STATO_0000359 equal diagonal Factor Analytic covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure FA1(q) factor-analytic structure is a covariance structure which is specified for q factors
http://purl.obolibrary.org/obo/STATO_0000360 no diagonal Factor Analytic covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure FA0(q) factor-analytic structure is a covariance structure which is specified for q factors
http://purl.obolibrary.org/obo/STATO_0000361 Factor Analytic covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure FA(q) factor-analytic structure is a covariance structure which is specified for q factors
http://purl.obolibrary.org/obo/STATO_0000362 compound symmetry covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure CS compound symmetry covariance structure is a covariance structure which means that all the variances are equal and all the covariances are equal.
http://purl.obolibrary.org/obo/STATO_0000363 heterogeneous compound symmetry covariance structure http://purl.obolibrary.org/obo/STATO_0000362 compound symmetry covariance structure CSH heterogenous compound symmetry structure is a compound symmetry covariance structure which has a different variance parameter for each diagonal element, and it uses the square roots of these parameters in the off-diagonal entries.
http://purl.obolibrary.org/obo/STATO_0000364 first order autoregressive moving average covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure ARMA(1,1)
http://purl.obolibrary.org/obo/STATO_0000365 first order autoregressive covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure AR(1) first order autoregressive covariance structure is a covariance structure where correlations among errors decline exponentially with distance
http://purl.obolibrary.org/obo/STATO_0000366 heterogeneous first-order autoregressive covariance structure http://purl.obolibrary.org/obo/STATO_0000365 first order autoregressive covariance structure ARH(1)
http://purl.obolibrary.org/obo/STATO_0000367 Ante-dependence covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure ANTE(1) Ante-dependence covariance structure is a covariance structure which specifies that the covariance between two time points is a function of the product of variances at both points (hence allowing hetrogenity of error variance across measures to affect the correlation) and the product of the correlations at the distances up to the one chosen.
http://purl.obolibrary.org/obo/STATO_0000399 interquartile mean http://purl.obolibrary.org/obo/STATO_0000163 trimmed mean IQM The interquartile mean (IQM) (or midmean) is a statistical measure of central tendency based on the truncated mean of the interquartile range.
In the calculation of the IQM, only the data in the second and third quartiles is used (as in the interquartile range), and the lowest 25% and the highest 25% of the scores are discarded. These points are called the first and third quartiles, hence the name of the IQM.
http://purl.obolibrary.org/obo/STATO_0000400 quadratic mean http://purl.obolibrary.org/obo/STATO_0000029 measure of central tendency root mean square The root mean square (abbreviated RMS or rms), also known as the quadratic mean, in statistics is a statistical measure of central tendency defined as the square root of the mean of the squares of a sample.
( To find the root mean square of a set of numbers, square all the numbers in the set and then find the arithmetic mean of the squares. Take the square root of the result. This is the root mean square.)
http://purl.obolibrary.org/obo/STATO_0000287 two tailed test http://purl.obolibrary.org/obo/OBI_0200000 data transformation two sided test a two tailed test is a statistical test which assess the null hypothesis of absence of difference assuming a symmetric (not skewed) underlying probability distribution by allocating half of the significance level selected to each of the direction of change which could explain a difference (for example, a difference can be an excess or a loss).
http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity http://purl.obolibrary.org/obo/BFO_0000040 material entity Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity.
http://purl.obolibrary.org/obo/CHEBI_33250 atom http://purl.obolibrary.org/obo/BFO_0000040 material entity A chemical entity constituting the smallest component of an element having the chemical properties of the element.
http://purl.obolibrary.org/obo/BFO_0000005 dependent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant A continuant that is either dependent on one or other independent continuant bearers or inheres in or is borne by other entities.
http://purl.obolibrary.org/obo/BFO_0000006 spatial region http://purl.obolibrary.org/obo/BFO_0000002 continuant A continuant that is neither bearer of quality entities nor inheres in any other entities.
http://purl.obolibrary.org/obo/BFO_0000009 two dimensional region http://purl.obolibrary.org/obo/BFO_0000006 spatial region A spatial region with two dimensions.
http://purl.obolibrary.org/obo/BFO_0000016 disposition http://purl.obolibrary.org/obo/BFO_0000017 realizable entity A realizable entity that essentially causes a specific process or transformation in the object in which it inheres, under specific circumstances and in conjunction with the laws of nature. A general formula for dispositions is: X (object has the disposition D to (transform, initiate a process) R under conditions C.
http://purl.obolibrary.org/obo/BFO_0000017 realizable entity http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.
http://purl.obolibrary.org/obo/BFO_0000018 zero dimensional region http://purl.obolibrary.org/obo/BFO_0000006 spatial region A spatial region with no dimensions.
http://purl.obolibrary.org/obo/BFO_0000019 quality http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant A specifically dependent continuant that is exhibited if it inheres in an entity or entities at all (a categorical property).
http://purl.obolibrary.org/obo/BFO_0000023 role http://purl.obolibrary.org/obo/BFO_0000017 realizable entity A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts.
http://purl.obolibrary.org/obo/BFO_0000026 one dimensional region http://purl.obolibrary.org/obo/BFO_0000006 spatial region A spatial region with one dimension.
http://purl.obolibrary.org/obo/BFO_0000028 three dimensional region http://purl.obolibrary.org/obo/BFO_0000006 spatial region A spatial region with three dimensions.
http://purl.obolibrary.org/obo/BFO_0000031 generically dependent continuant http://purl.obolibrary.org/obo/BFO_0000005 dependent continuant A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time.
http://purl.obolibrary.org/obo/BFO_0000034 function http://purl.obolibrary.org/obo/BFO_0000016 disposition A realizable entity the manifestation of which is an essentially end-directed activity of a continuant entity in virtue of that continuant entity being a specific kind of entity in the kind or kinds of contexts that it is made for.
http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/BFO_0000004 independent continuant An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.
http://purl.obolibrary.org/obo/IAO_0000001 conditional specification http://purl.obolibrary.org/obo/IAO_0000033 directive information entity a directive information entity that specifies what should happen if the trigger condition is fulfilled
http://purl.obolibrary.org/obo/IAO_0000003 measurement unit label http://purl.obolibrary.org/obo/IAO_0000009 data item label A data item label that denotes a unit of measure.
http://purl.obolibrary.org/obo/IAO_0000005 objective specification http://purl.obolibrary.org/obo/IAO_0000033 directive information entity a directive information entity that describes an intended process endpoint.
http://purl.obolibrary.org/obo/IAO_0000007 action specification http://purl.obolibrary.org/obo/IAO_0000033 directive information entity a directive information entity that describes an action the bearer will take
http://purl.obolibrary.org/obo/IAO_0000015 information carrier http://purl.obolibrary.org/obo/BFO_0000019 quality A quality of an information bearer that imparts the information content
http://purl.obolibrary.org/obo/IAO_0000028 symbol http://purl.obolibrary.org/obo/IAO_0000030 information content entity An information content entity that is a mark or character used as a conventional representation of another entity.
http://purl.obolibrary.org/obo/IAO_0000030 information content entity http://purl.obolibrary.org/obo/BFO_0000031 generically dependent continuant an information content entity is an entity that is generically dependent on some material entity and stands in relation of aboutness to some entity
http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum http://purl.obolibrary.org/obo/IAO_0000109 measurement data item a scalar measurement datum is a measurement datum that is composed of two parts, numerals and a unit label.
http://purl.obolibrary.org/obo/IAO_0000033 directive information entity http://purl.obolibrary.org/obo/IAO_0000030 information content entity An information content entity whose concretizations indicate to their bearer how to realize them in a process.
http://purl.obolibrary.org/obo/IAO_0000037 dot plot http://purl.obolibrary.org/obo/IAO_0000038 graph A dot plot is a report graph which is a graphical representation of data where each data point is represented by a single dot placed on coordinates corresponding to data point values in particular dimensions.
http://purl.obolibrary.org/obo/IAO_0000038 graph http://purl.obolibrary.org/obo/IAO_0000309 diagram A diagram that presents one or more tuples of information by mapping those tuples in to a two dimensional space in a non arbitrary way.
http://purl.obolibrary.org/obo/IAO_0000055 rule http://purl.obolibrary.org/obo/IAO_0000001 conditional specification a rule is an executable which guides, defines, restricts actions
http://purl.obolibrary.org/obo/IAO_0000064 algorithm http://purl.obolibrary.org/obo/IAO_0000104 plan specification A plan specification which describes inputs, output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata.
http://purl.obolibrary.org/obo/IAO_0000078 curation status specification http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.
http://purl.obolibrary.org/obo/IAO_0000088 report http://purl.obolibrary.org/obo/IAO_0000030 information content entity An information content entity assembled by an author for the purpose of providing information for an audience, and that is meant to provide an accurate account of something that happened.
http://purl.obolibrary.org/obo/IAO_0000100 data set http://purl.obolibrary.org/obo/IAO_0000027 data item A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets.
http://purl.obolibrary.org/obo/IAO_0000101 image http://purl.obolibrary.org/obo/IAO_0000308 figure An image is an affine projection to a two dimensional surface, of measurements of some quality of an entity or entities repeated at regular intervals across a spatial range, where the measurements are represented as color and luminosity on the projected on surface.
http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part http://purl.obolibrary.org/obo/IAO_0000027 data item data about an ontology part is a data item about a part of an ontology, for example a term
http://purl.obolibrary.org/obo/IAO_0000104 plan specification http://purl.obolibrary.org/obo/IAO_0000033 directive information entity a directive information entity that, when concretized, is realized in a process in which the bearer tries to achieve the objectives, in part by taking the actions specified.
http://purl.obolibrary.org/obo/IAO_0000129 version number http://purl.obolibrary.org/obo/IAO_0000028 symbol A version number is an information content entity which is a sequence of characters borne by part of each of a class of manufactured products or its packaging and indicates its order within a set of other products having the same name.
http://purl.obolibrary.org/obo/IAO_0000144 conclusion textual entity http://purl.obolibrary.org/obo/OBI_0001909 conclusion based on data A textual entity that expresses the results of reasoning about a problem, for instance as typically found towards the end of scientific papers.
http://purl.obolibrary.org/obo/IAO_0000178 material information bearer http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity in which a concretization of an information content entity inheres.
http://purl.obolibrary.org/obo/IAO_0000306 table http://purl.obolibrary.org/obo/IAO_0000300 textual entity A textual entity that contains a two-dimensional arrangement of texts repeated at regular intervals across a spatial range, such that the spatial relationships among the constituent texts expresses propositions
http://purl.obolibrary.org/obo/IAO_0000308 figure http://purl.obolibrary.org/obo/IAO_0000030 information content entity An information content entity consisting of a two dimensional arrangement of information content entities such that the arrangement itself is about something.
http://purl.obolibrary.org/obo/IAO_0000309 diagram http://purl.obolibrary.org/obo/IAO_0000308 figure A figure that expresses one or more propositions
http://purl.obolibrary.org/obo/IAO_0000400 cartesian spatial coordinate datum http://purl.obolibrary.org/obo/IAO_0000027 data item A cartesian spatial coordinate datum is a representation of a point in a spatial region, in which equal changes in the magnitude of a coordinate value denote length qualities with the same magnitude
http://purl.obolibrary.org/obo/IAO_0000414 mass measurement datum http://purl.obolibrary.org/obo/IAO_0000109 measurement data item A scalar measurement datum that is the result of measurement of mass quality
http://purl.obolibrary.org/obo/IAO_0000416 time measurement datum http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum A scalar measurement datum that is the result of measuring a temporal interval
http://purl.obolibrary.org/obo/IAO_0000572 documenting http://purl.obolibrary.org/obo/OBI_0000011 planned process a planned process in which input information is used to create or add to a report
http://purl.obolibrary.org/obo/OBI_0000010 fluorescent reporter intensity http://purl.obolibrary.org/obo/IAO_0000109 measurement data item A measurement datum that represents the output of a scanner measuring the intensity value for each fluorescent reporter.
http://purl.obolibrary.org/obo/OBI_0000011 planned process http://purl.obolibrary.org/obo/BFO_0000007 process A processual entity that realizes a plan which is the concretization of a plan specification.
http://purl.obolibrary.org/obo/OBI_0000015 biological feature identification objective http://purl.obolibrary.org/obo/IAO_0000005 objective specification Biological_feature_identification_objective is an objective role carried out by the proposition defining the aim of a study designed to examine or characterize a particular biological feature.
http://purl.obolibrary.org/obo/OBI_0000047 processed material http://purl.obolibrary.org/obo/BFO_0000040 material entity Is a material entity that is created or changed during material processing.
http://purl.obolibrary.org/obo/OBI_0000066 investigation http://purl.obolibrary.org/obo/OBI_0000011 planned process a planned process that consists of parts: planning, study design execution, documentation and which produce conclusion(s).
http://purl.obolibrary.org/obo/OBI_0000067 evaluant role http://purl.obolibrary.org/obo/BFO_0000023 role a role that inheres in a material entity that is realized in an assay in which data is generated about the bearer of the evaluant role
http://purl.obolibrary.org/obo/OBI_0000071 quantitative confidence value http://purl.obolibrary.org/obo/IAO_0000027 data item A data item which is used to indicate the degree of uncertainty about a measurement.
http://purl.obolibrary.org/obo/OBI_0000079 culture medium http://purl.obolibrary.org/obo/OBI_0000047 processed material a processed material that provides the needed nourishment for microorganisms or cells grown in vitro.
http://purl.obolibrary.org/obo/OBI_0000097 participant under investigation role http://purl.obolibrary.org/obo/BFO_0000023 role A role that is realized through the execution of a study design in which the bearer of the role participates and in which data about that bearer is collected.
http://purl.obolibrary.org/obo/OBI_0000109 biological vector role http://purl.obolibrary.org/obo/OBI_0000319 material to be added role a biological vector role is a material to be added role that is realized by the process of transmitting material to the organism that is the target of the transmission.
http://purl.obolibrary.org/obo/OBI_0000112 specimen role http://purl.obolibrary.org/obo/BFO_0000023 role a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation
http://purl.obolibrary.org/obo/OBI_0000113 sequence feature identification objective http://purl.obolibrary.org/obo/OBI_0000015 biological feature identification objective Sequence_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize molecular features exhibited at the level of a macromolecular sequence, e.g. nucleic acid, protein, polysaccharide.
http://purl.obolibrary.org/obo/OBI_0000115 intervention design http://purl.obolibrary.org/obo/OBI_0500000 study design An intervention design is a study design in which a controlled process applied to the subjects (the intervention) serves as the independent variable manipulated by the experimentalist. The treatment (perturbation or intervention) defined can be defined as a combination of values taken by independent variable manipulated by the experimentalists are applied to the recruited subjects assigned (possibly by applying specific methods) to treatment groups. The specificity of intervention design is the fact that independent variables are being manipulated and a response of the biological system is evaluated via response variables as monitored by possibly a series of assays.
http://purl.obolibrary.org/obo/OBI_0000118 gene list http://purl.obolibrary.org/obo/IAO_0000100 data set A data set of the names or identifiers of genes that are the outcome of an analysis or have been put together for the purpose of an analysis.
http://purl.obolibrary.org/obo/OBI_0000131 molecular feature identification objective http://purl.obolibrary.org/obo/OBI_0000015 biological feature identification objective Molecular_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize molecular features of a biological system, e.g. expression profiling, copy number of molecular components, epigenetic modifications.
http://purl.obolibrary.org/obo/OBI_0000175 p-value http://purl.obolibrary.org/obo/OBI_0000071 quantitative confidence value A quantitative confidence value that represents the probability of obtaining a result at least as extreme as that actually obtained, assuming that the actual value was the result of chance alone.
http://purl.obolibrary.org/obo/OBI_0000181 population http://purl.obolibrary.org/obo/BFO_0000040 material entity a population is a collection of individuals from the same taxonomic class living, counted or sampled at a particular site or in a particular area
http://purl.obolibrary.org/obo/OBI_0000185 imaging assay http://purl.obolibrary.org/obo/OBI_0000070 assay An imaging assay is an assay to produce a picture of an entity. definition_source: OBI.
http://purl.obolibrary.org/obo/OBI_0000245 organization http://purl.obolibrary.org/obo/BFO_0000040 material entity An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members.
http://purl.obolibrary.org/obo/OBI_0000272 protocol http://purl.obolibrary.org/obo/IAO_0000104 plan specification A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process.
http://purl.obolibrary.org/obo/OBI_0000274 adding a material entity into a target http://purl.obolibrary.org/obo/OBI_0000652 material combination is a process with the objective to place a material entity bearing the 'material to be added role' into a material bearing the 'target of material addition role'.
http://purl.obolibrary.org/obo/OBI_0000275 analyte role http://purl.obolibrary.org/obo/BFO_0000023 role A role borne by a molecular entity or an atom and realized in an analyte assay which achieves the objective to measure the magnitude/concentration/amount of the analyte in the entity bearing evaluant role
http://purl.obolibrary.org/obo/OBI_0000319 material to be added role http://purl.obolibrary.org/obo/BFO_0000023 role material to be added role is a protocol participant role realized by a material which is added into a material bearing the target of material addition role in a material addition process
http://purl.obolibrary.org/obo/OBI_0000338 drawing a conclusion based on data http://purl.obolibrary.org/obo/OBI_0000011 planned process A planned process in which data gathered in an investigation is evaluated in the context of existing knowledge with the objective to generate more general conclusions or to conclude that the data does not allow one to draw general conclusion
http://purl.obolibrary.org/obo/OBI_0000339 planning http://purl.obolibrary.org/obo/BFO_0000007 process a process of creating or modifying a plan specification
http://purl.obolibrary.org/obo/OBI_0000367 light emission function http://purl.obolibrary.org/obo/OBI_0000374 excitation function A light emission function is an excitation function to excite a material to a specific excitation state that it emits light.
http://purl.obolibrary.org/obo/OBI_0000370 contain function http://purl.obolibrary.org/obo/BFO_0000034 function A contain function is a function to constrain a material entities location in space
http://purl.obolibrary.org/obo/OBI_0000371 heat function http://purl.obolibrary.org/obo/BFO_0000034 function A heat function is a function that increases the internal kinetic energy of a material
http://purl.obolibrary.org/obo/OBI_0000372 material separation function http://purl.obolibrary.org/obo/BFO_0000034 function A material separation function is a function that increases the resolution between two or more material entities. The to distinction between the entities is usually based on some associated physical quality.
http://purl.obolibrary.org/obo/OBI_0000374 excitation function http://purl.obolibrary.org/obo/BFO_0000034 function A excitation function is a function to inject energy by bombarding a material with energetic particles (e.g., photons) thereby imbuing internal material components such as electrons with additional energy. These internal, 'excited' particles may lead to the rupturing of covalent chemical bonds or may quickly relax back to there unexcited state with an exponential time course thereby locally emitting energy in the form of photons.
http://purl.obolibrary.org/obo/OBI_0000378 filter function http://purl.obolibrary.org/obo/OBI_0000372 material separation function A filter function is a function to prevent the flow of certain entities based on a quality or qualities of the entity while allowing entities which have different qualities to pass through
http://purl.obolibrary.org/obo/OBI_0000387 cool function http://purl.obolibrary.org/obo/BFO_0000034 function A cool function is a function to decrease the internal kinetic energy of a material below the initial kinetic energy of that type of material.
http://purl.obolibrary.org/obo/OBI_0000399 solid support function http://purl.obolibrary.org/obo/BFO_0000034 function A solid support function is a function of a device on which an entity is kept in a defined position and prevented in its movement
http://purl.obolibrary.org/obo/OBI_0000401 environment control function http://purl.obolibrary.org/obo/BFO_0000034 function An environmental control function is a function that regulates a contained environment within specified parameter ranges. For example the control of light exposure, humidity and temperature.
http://purl.obolibrary.org/obo/OBI_0000403 sort function http://purl.obolibrary.org/obo/OBI_0000372 material separation function A sort function is a function to distinguish material components based on some associated physical quality or entity and to partition the separate components into distinct fractions according to a defined order.
http://purl.obolibrary.org/obo/OBI_0000411 cloning vector role http://purl.obolibrary.org/obo/OBI_0000109 biological vector role a vector role played by a small, self-replicating DNA or RNA molecule - usually a plasmid or chromosome - and realized in a process whereby foreign DNA or RNA is inserted into the vector during the process of cloning.
http://purl.obolibrary.org/obo/OBI_0000416 cloning insert role http://purl.obolibrary.org/obo/BFO_0000023 role cloning insert role is a role which inheres in DNA or RNA and is realized by the process of being inserted into a cloning vector in a cloning process.
http://purl.obolibrary.org/obo/OBI_0000425 averaging objective http://purl.obolibrary.org/obo/OBI_0200166 data transformation objective An averaging objective is a data transformation objective where the aim is to perform mean calculations on the input of the data transformation.
http://purl.obolibrary.org/obo/OBI_0000434 adding material objective http://purl.obolibrary.org/obo/OBI_0000686 material combination objective is the specification of an objective to add a material into a target material. The adding is asymmetric in the sense that the target material largely retains its identity
http://purl.obolibrary.org/obo/OBI_0000437 analyte measurement objective http://purl.obolibrary.org/obo/OBI_0000441 assay objective an assay objective to determine the presence or concentration of an analyte in the evaluant
http://purl.obolibrary.org/obo/OBI_0000441 assay objective http://purl.obolibrary.org/obo/IAO_0000005 objective specification an objective specification to determine a specified type of information about an evaluated entity (the material entity bearing evaluant role)
http://purl.obolibrary.org/obo/OBI_0000443 analyte assay http://purl.obolibrary.org/obo/OBI_0000070 assay An assay with the objective to capture information about the presence, concentration, or amount of an analyte in an evaluant.
http://purl.obolibrary.org/obo/OBI_0000444 target of material addition role http://purl.obolibrary.org/obo/BFO_0000023 role target of material addition role is a role realized by an entity into which a material is added in a material addition process
http://purl.obolibrary.org/obo/OBI_0000451 normalized data set http://purl.obolibrary.org/obo/IAO_0000100 data set A data set that is produced as the output of a normalization data transformation.
http://purl.obolibrary.org/obo/OBI_0000453 measure function http://purl.obolibrary.org/obo/BFO_0000034 function Measure function is a function that is borne by a processed material and realized in a process in which information about some entity is expressed relative to some reference.
http://purl.obolibrary.org/obo/OBI_0000471 study design execution http://purl.obolibrary.org/obo/OBI_0000011 planned process a planned process that realizes the concretization of a study design
http://purl.obolibrary.org/obo/OBI_0000626 DNA sequencing http://purl.obolibrary.org/obo/OBI_0600047 sequencing assay DNA sequencing is a sequencing process which uses deoxyribonucleic acid as input and results in a the creation of DNA sequence information artifact using a DNA sequencer instrument.
http://purl.obolibrary.org/obo/OBI_0000639 material separation objective http://purl.obolibrary.org/obo/OBI_0000456 material transformation objective is an objective to transform a material entity into spatially separated components.
http://purl.obolibrary.org/obo/OBI_0000649 data set of features http://purl.obolibrary.org/obo/IAO_0000100 data set A data set that is produced as the output of a descriptive statistical calculation data transformation and consists of producing a data set that represents one or more features of interest about the input data set.
http://purl.obolibrary.org/obo/OBI_0000650 differential expression analysis data transformation http://purl.obolibrary.org/obo/OBI_0200000 data transformation A differential expression analysis data transformation is a data transformation that has objective differential expression analysis and that consists of
http://purl.obolibrary.org/obo/OBI_0000652 material combination http://purl.obolibrary.org/obo/OBI_0000094 material processing is a material processing with the objective to combine two or more material entities as input into a single material entity as output.
http://purl.obolibrary.org/obo/OBI_0000659 specimen collection http://purl.obolibrary.org/obo/OBI_0000011 planned process A planned process with the objective of collecting a specimen.
http://purl.obolibrary.org/obo/OBI_0000662 error corrected data set http://purl.obolibrary.org/obo/IAO_0000100 data set A data set that is produced as the output of an error correction data transformation and consists of producing a data set which has had erroneous contributions from the input to the data transformation removed (corrected for).
http://purl.obolibrary.org/obo/OBI_0000668 error correction data transformation http://purl.obolibrary.org/obo/OBI_0200000 data transformation An error correction data transformation is a data transformation that has the objective of error correction, where the aim is to remove (correct for) erroneous contributions from the input to the data transformation.
http://purl.obolibrary.org/obo/OBI_0000671 sample from organism http://purl.obolibrary.org/obo/OBI_0001479 tissue specimen a material obtained from an organism in order to be a representative of the whole
http://purl.obolibrary.org/obo/OBI_0000673 statistical hypothesis test http://purl.obolibrary.org/obo/OBI_0200000 data transformation "A statistical test provides a mechanism for making quantitative decisions about a process or processes".
http://purl.obolibrary.org/obo/OBI_0000678 portioning objective http://purl.obolibrary.org/obo/OBI_0000639 material separation objective A material separation objective aiming to separate material into multiple portions, each of which contains a similar composition of the input material.
http://purl.obolibrary.org/obo/OBI_0000681 separation into different composition objective http://purl.obolibrary.org/obo/OBI_0000639 material separation objective A material separation objective aiming to separate a material entity that has parts of different types, and end with at least one output that is a material with parts of fewer types (modulo impurities).
http://purl.obolibrary.org/obo/OBI_0000684 specimen collection objective http://purl.obolibrary.org/obo/IAO_0000005 objective specification A objective specification to obtain a material entity for potential use as an input during an investigation.
http://purl.obolibrary.org/obo/OBI_0000686 material combination objective http://purl.obolibrary.org/obo/OBI_0000456 material transformation objective is an objective to obtain an output material that contains several input materials.
http://purl.obolibrary.org/obo/OBI_0000731 recombinant vector http://purl.obolibrary.org/obo/OBI_0000047 processed material A recombinant vector is created by a recombinant vector cloning process, and contains nucleic acids that can be amplified. It retains functions of the original cloning vector.
http://purl.obolibrary.org/obo/OBI_0000737 cloning vector http://purl.obolibrary.org/obo/OBI_1110108 material to be added A cloning vector is an engineered material that is used as an input material for a recombinant vector cloning process to carry inserted nucleic acids. It contains an origin of replication for a specific destination host organism, encodes for a selectable gene product and contains a cloning site.
http://purl.obolibrary.org/obo/OBI_0000740 material sample role http://purl.obolibrary.org/obo/OBI_0000112 specimen role A material sample role is a specimen role borne by a material entity that is the output of a material sampling process.
http://purl.obolibrary.org/obo/OBI_0000744 material sampling process http://purl.obolibrary.org/obo/OBI_0000659 specimen collection A specimen gathering process with the objective to obtain a specimen that is representative of the input material entity
http://purl.obolibrary.org/obo/OBI_0000789 survival rate http://purl.obolibrary.org/obo/STATO_0000184 ratio A measurement data that represents the percentage of people or animals in a study or treatment group who are alive for a given period of time after diagnosis or initiation of monitoring.
http://purl.obolibrary.org/obo/OBI_0000806 material maintenance objective http://purl.obolibrary.org/obo/IAO_0000005 objective specification An objective specification maintains some or all of the qualities of a material over time.
http://purl.obolibrary.org/obo/OBI_0000811 primary structure of DNA macromolecule http://purl.obolibrary.org/obo/SO_0000001 region a quality of a DNA molecule that inheres in its bearer due to the order of its DNA nucleotide residues.
http://purl.obolibrary.org/obo/OBI_0000832 measurement device http://purl.obolibrary.org/obo/OBI_0000968 device A device in which a measure function inheres.
http://purl.obolibrary.org/obo/OBI_0000838 material maintenance http://purl.obolibrary.org/obo/OBI_0000011 planned process a process with that achieves the objective to maintain some or all of the characteristics of an input material over time
http://purl.obolibrary.org/obo/OBI_0000861 Likelihood-ratio test http://purl.obolibrary.org/obo/STATO_0000191 goodness of fit statistical test Likelihood-ratio test is a statistical test which evaluates the goodness-of-fit between two models and whether there is evidence of the need to move from a simple model to a more complicated one (where the simple model is nested within the complicated one)
http://purl.obolibrary.org/obo/OBI_0000889 survival curve http://purl.obolibrary.org/obo/IAO_0000573 line graph A survival curve is a report graph which is a graphical representation of data where the percentage of survival is plotted as a function of time.
http://purl.obolibrary.org/obo/OBI_0000916 flow cytometry assay http://purl.obolibrary.org/obo/OBI_0000070 assay An assay that uses a flow cytometer to detect fluorescence in individual particles that flow by a laser in solution.
http://purl.obolibrary.org/obo/OBI_0000924 labeled specimen http://purl.obolibrary.org/obo/OBI_0001936 molecular-labeled material A specimen that has been modified in order to be able to detect it in future experiments
http://purl.obolibrary.org/obo/OBI_0000931 study intervention http://purl.obolibrary.org/obo/OBI_0000011 planned process the part of the execution of an intervention design study which is varied between two or more subjects in the study
http://purl.obolibrary.org/obo/OBI_0000932 material separation device http://purl.obolibrary.org/obo/OBI_0000968 device A device with a separation function realized in a planed process
http://purl.obolibrary.org/obo/OBI_0000953 processed specimen http://purl.obolibrary.org/obo/OBI_0100051 specimen A specimen that has been intentionally physically modified.
http://purl.obolibrary.org/obo/OBI_0000963 categorical label http://purl.obolibrary.org/obo/IAO_0000009 data item label A label that is part of a categorical datum and that indicates the value of the data item on the categorical scale.
http://purl.obolibrary.org/obo/OBI_0000964 in live cell assay http://purl.obolibrary.org/obo/OBI_0000070 assay An assay in which a measurement is made by observing entities located in a live cell.
http://purl.obolibrary.org/obo/OBI_0000967 container http://purl.obolibrary.org/obo/OBI_0000968 device A device that can be used to restrict the location of material entities over time
http://purl.obolibrary.org/obo/OBI_0000984 dose http://purl.obolibrary.org/obo/IAO_0000109 measurement data item A measurement datum that measures the quantity of something that may be administered to an organism or that an organism may be exposed to. Quantities of nutrients, drugs, vaccines and toxins are referred to as doses.
http://purl.obolibrary.org/obo/OBI_0001010 nucleic acid extract http://purl.obolibrary.org/obo/OBI_0000953 processed specimen An extract that is the output of an extraction process in which nucleic acid molecules are isolated from a specimen.
http://purl.obolibrary.org/obo/OBI_0001032 light emission device http://purl.obolibrary.org/obo/OBI_0000968 device a device which has a function to emit light.
http://purl.obolibrary.org/obo/OBI_0001034 environmental control device http://purl.obolibrary.org/obo/OBI_0000968 device An environmental control device is a device which has the function to control some aspect of the environment such as temperature, or humidity.
http://purl.obolibrary.org/obo/OBI_0001172 dose response curve http://purl.obolibrary.org/obo/IAO_0000573 line graph A data item of paired values, one indicating the dose of a material, the other quantitating a measured effect at that dose. The dosing intervals are chosen so that effect values be interpolated by a plotting a curve.
http://purl.obolibrary.org/obo/OBI_0001225 genetic population background information http://purl.obolibrary.org/obo/OBI_0001404 genetic characteristics information a genetic characteristics information which is a part of genotype information that identifies the population of organisms
http://purl.obolibrary.org/obo/OBI_0001265 FWER adjusted p-value http://purl.obolibrary.org/obo/OBI_0000662 error corrected data set A quantitative confidence value resulting from a multiple testing error correction method which adjusts the p-value used as input to control for Type I error in the context of multiple pairwise tests
http://purl.obolibrary.org/obo/OBI_0001305 genotype information http://purl.obolibrary.org/obo/OBI_0001404 genetic characteristics information a genetic characteristics information that is about the genetic material of an organism and minimally includes information about the genetic background and can in addition contain information about specific alleles, genetic modifications, etc.
http://purl.obolibrary.org/obo/OBI_0001331 transcription profiling identification objective http://purl.obolibrary.org/obo/OBI_0000131 molecular feature identification objective A molecular feature identification objective that aims to characterize the abundance of transcripts
http://purl.obolibrary.org/obo/OBI_0001352 allele information http://purl.obolibrary.org/obo/OBI_0001364 genetic alteration information a genetic alteration information that about one of two or more alternative forms of a gene or marker sequence and differing from other alleles at one or more mutational sites based on sequence. Polymorphisms are included in this definition.
http://purl.obolibrary.org/obo/OBI_0001364 genetic alteration information http://purl.obolibrary.org/obo/OBI_0001404 genetic characteristics information a genetic characteristics information that is about known changes or the lack thereof from the genetic background, including allele information, duplication, insertion, deletion, etc.
http://purl.obolibrary.org/obo/OBI_0001404 genetic characteristics information http://purl.obolibrary.org/obo/IAO_0000027 data item a data item that is about genetic material including polymorphisms, disease alleles, and haplotypes.
http://purl.obolibrary.org/obo/OBI_0001444 genotyping design http://purl.obolibrary.org/obo/OBI_0500000 study design A study design that classifies an individual or group of individuals on the basis of alleles, haplotypes, SNPs.
http://purl.obolibrary.org/obo/OBI_0001479 tissue specimen http://purl.obolibrary.org/obo/OBI_0100051 specimen A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm).
http://purl.obolibrary.org/obo/OBI_0001554 rate measurement datum http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum A scalar measurement datum that represents the number of events occuring over a time interval
http://purl.obolibrary.org/obo/OBI_0001573 DNA sequence data http://purl.obolibrary.org/obo/OBI_0000973 sequence data A sequence data item that is about the primary structure of DNA
http://purl.obolibrary.org/obo/OBI_0001834 drawing a conclusion http://purl.obolibrary.org/obo/OBI_0000011 planned process A planned process in which new information is inferred from existing information.
http://purl.obolibrary.org/obo/OBI_0001865 assay array http://purl.obolibrary.org/obo/OBI_0000968 device A device made to be used in an analyte assay for immobilization of substances that bind the analyte at regular spatial positions on a surface.
http://purl.obolibrary.org/obo/OBI_0001909 conclusion based on data http://purl.obolibrary.org/obo/IAO_0000030 information content entity An information content entity that is inferred from data.
http://purl.obolibrary.org/obo/OBI_0001912 cell freezing medium http://purl.obolibrary.org/obo/OBI_0000047 processed material A processed material that serves as a liquid vehicle for freezing cells for long term quiescent stroage, which contains chemicls needed to sustain cell viability across freeze-thaw cycles.
http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification http://purl.obolibrary.org/obo/OBI_0001933 value specification A value specification that is specifies one category out of a fixed number of nominal categories
http://purl.obolibrary.org/obo/OBI_0001931 scalar value specification http://purl.obolibrary.org/obo/OBI_0001933 value specification A value specification that consists of two parts: a numeral and a unit label
http://purl.obolibrary.org/obo/OBI_0001933 value specification http://purl.obolibrary.org/obo/IAO_0000030 information content entity An information content entity that specifies a value within a classification scheme or on a quantitative scale.
http://purl.obolibrary.org/obo/OBI_0001936 molecular-labeled material http://purl.obolibrary.org/obo/OBI_0000047 processed material a material entity that is the specified output of an addition of molecular label process that aims to label some molecular target to allow for its detection in a detection of molecular label assay
http://purl.obolibrary.org/obo/OBI_0100026 organism http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs.
http://purl.obolibrary.org/obo/OBI_0100051 specimen http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity that has the specimen role.
http://purl.obolibrary.org/obo/OBI_0100064 screening library http://purl.obolibrary.org/obo/OBI_0000047 processed material a screening library is a collection of materials engineered to identify qualities of a subset of its members during a screening process?
http://purl.obolibrary.org/obo/OBI_0200031 differential expression analysis objective http://purl.obolibrary.org/obo/OBI_0200166 data transformation objective A differential expression analysis objective is a data transformation objective whose input consists of expression levels of entities (such as transcripts or proteins), or of sets of such expression levels, under two or more conditions and whose output reflects which of these are likely to have different expression across such conditions.
http://purl.obolibrary.org/obo/OBI_0200036 Benjamini and Hochberg false discovery rate correction method http://purl.obolibrary.org/obo/OBI_0200163 false discovery rate correction method A data transformation process in which the Benjamini and Hochberg method sequential p-value procedure is applied with the aim of correcting false discovery rate
http://purl.obolibrary.org/obo/OBI_0200049 Benjamini and Yekutieli false discovery rate correction method http://purl.obolibrary.org/obo/OBI_0200163 false discovery rate correction method A data transformation in which the Benjamini and Yekutieli method is applied with the aim of correcting false discovery rate
http://purl.obolibrary.org/obo/OBI_0200066 Holm-Bonferroni family-wise error rate correction method http://purl.obolibrary.org/obo/OBI_0200073 family wise error rate correction method a data transformation that performs more than one hypothesis test simultaneously, a closed-test procedure, that controls the familywise error rate for all the k hypotheses at level α in the strong sense. Objective: multiple testing correction
http://purl.obolibrary.org/obo/OBI_0200078 descriptive statistical calculation objective http://purl.obolibrary.org/obo/OBI_0200166 data transformation objective A descriptive statistical calculation objective is a data transformation objective which concerns any calculation intended to describe a feature of a data set, for example, its center or its variability.
http://purl.obolibrary.org/obo/OBI_0200094 logarithmic transformation http://purl.obolibrary.org/obo/OBI_0200169 normalization data transformation A logarithmic transformation is a data transformation consisting in the application of the logarithm function with a given base a (where a>0 and a is not equal to 1) to a (one dimensional) positive real number input. The logarithm function with base a can be defined as the inverse of the exponential function with the same base. See e.g. http://en.wikipedia.org/wiki/Logarithm.
http://purl.obolibrary.org/obo/OBI_0200102 regression analysis method http://purl.obolibrary.org/obo/OBI_0200000 data transformation Regression analysis is a descriptive statistics technique that examines the relation of a dependent variable (response variable) to specified independent variables (explanatory variables). Regression analysis can be used as a descriptive method of data analysis (such as curve fitting) without relying on any assumptions about underlying processes generating the data.
http://purl.obolibrary.org/obo/OBI_0200117 mode calculation http://purl.obolibrary.org/obo/OBI_0200184 descriptive statistical calculation data transformation A mode calculation is a descriptive statistics calculation in which the mode is calculated which is the most common value in a data set. It is most often used as a measure of center for discrete data.
http://purl.obolibrary.org/obo/OBI_0200119 median calculation http://purl.obolibrary.org/obo/OBI_0200184 descriptive statistical calculation data transformation A median calculation is a descriptive statistics calculation in which the midpoint of the data set (the 0.5 quantile) is calculated. First, the observations are sorted in increasing order. For an odd number of observations, the median is the middle value of the sorted data. For an even number of observations, the median is the average of the two middle values.
http://purl.obolibrary.org/obo/OBI_0200166 data transformation objective http://purl.obolibrary.org/obo/IAO_0000005 objective specification An objective specification to transformation input data into output data
http://purl.obolibrary.org/obo/OBI_0200168 correction objective http://purl.obolibrary.org/obo/OBI_0200166 data transformation objective A correction objective is a data transformation objective where the aim is to correct for error, noise or other impairments to the input of the data transformation or derived from the data transformation itself
http://purl.obolibrary.org/obo/OBI_0200169 normalization data transformation http://purl.obolibrary.org/obo/OBI_0200000 data transformation A normalization data transformation is a data transformation that has objective normalization.
http://purl.obolibrary.org/obo/OBI_0200170 averaging data transformation http://purl.obolibrary.org/obo/OBI_0200000 data transformation An averaging data transformation is a data transformation that has objective averaging.
http://purl.obolibrary.org/obo/OBI_0200176 Fisher's exact test http://purl.obolibrary.org/obo/OBI_0000673 statistical hypothesis test Fisher's exact test is a data transformation used to determine if there are nonrandom associations between two Fisher's exact test is a statistical significance test used in the analysis of contingency tables where sample sizes are small where the significance of the deviation from a null hypothesis can be calculated exactly, rather than relying on an approximation that becomes exact in the limit as the sample size grows to infinity, as with many statistical tests.
http://purl.obolibrary.org/obo/OBI_0200177 center calculation objective http://purl.obolibrary.org/obo/OBI_0200166 data transformation objective A center calculation objective is a data transformation objective where the aim is to calculate the center of an input data set.
http://purl.obolibrary.org/obo/OBI_0200181 center calculation data transformation http://purl.obolibrary.org/obo/OBI_0200000 data transformation A center calculation data transformation is a data transformation that has objective of center calculation.
http://purl.obolibrary.org/obo/OBI_0200184 descriptive statistical calculation data transformation http://purl.obolibrary.org/obo/OBI_0200000 data transformation A descriptive statistical calculation data transformation is a data transformation that has objective descriptive statistical calculation and which concerns any calculation intended to describe a feature of a data set, for example, its center or its variability.
http://purl.obolibrary.org/obo/OBI_0200186 error correction objective http://purl.obolibrary.org/obo/OBI_0200168 correction objective An error correction objective is a data transformation objective where the aim is to remove (correct for) erroneous contributions arising from the input data, or the transformation itself.
http://purl.obolibrary.org/obo/OBI_0200191 gene list visualization http://purl.obolibrary.org/obo/OBI_0200111 data visualization Adata visualization which has input of a gene list and produces an output of a report graph which is capable of rendering data of this type.
http://purl.obolibrary.org/obo/OBI_0200194 survival analysis data transformation http://purl.obolibrary.org/obo/OBI_0200000 data transformation A data transformation which has the objective of performing survival analysis.
http://purl.obolibrary.org/obo/OBI_0200200 chi square test http://purl.obolibrary.org/obo/OBI_0000673 statistical hypothesis test The chi-square test is a data transformation with the objective of statistical hypothesis testing, in which the sampling distribution of the test statistic is a chi-square distribution when the null hypothesis is true, or any in which this is asymptotically true, meaning that the sampling distribution (if the null hypothesis is true) can be made to approximate a chi-square distribution as closely as desired by making the sample size large enough.
http://purl.obolibrary.org/obo/OBI_0300311 observation design http://purl.obolibrary.org/obo/OBI_0500000 study design observation design is a study design in which subjects are monitored in the absence of any active intervention by experimentalists.
http://purl.obolibrary.org/obo/OBI_0302884 extraction http://purl.obolibrary.org/obo/OBI_0600014 material component separation A material separation in which a desired component of an input material is separated from the remainder
http://purl.obolibrary.org/obo/OBI_0302900 group randomization http://purl.obolibrary.org/obo/OBI_0600015 group assignment A group assignment which relies on chance to assign materials to a group of materials in order to avoid bias in experimental set up.
http://purl.obolibrary.org/obo/OBI_0302903 nucleic acid hybridization http://purl.obolibrary.org/obo/OBI_0000094 material processing a planned process by which totally or partially complementary, single-stranded nucleic acids are combined into a single molecule called heteroduplex or homoduplex to an extent depending on the amount of complementarity.
http://purl.obolibrary.org/obo/OBI_0400044 flow cytometer http://purl.obolibrary.org/obo/OBI_0400137 cytometer A flow_cytometer is an instrument for counting, examining and sorting microscopic particles in suspension. It allows simultaneous multiparametric analysis of the physical and/or chemical characteristics of single cells flowing through an optical and/or electronic detection apparatus. A flow cytometer is an instrument that can be used to quantitatively measure the properties of individual cells in a flowing medium.
http://purl.obolibrary.org/obo/OBI_0400065 light source http://purl.obolibrary.org/obo/OBI_0001032 light emission device A light source is an optical subsystem that provides light for use in a distant area using a delivery system (e.g., fiber optics). Light sources may include one of a variety of lamps (e.g., xenon, halogen, mercury). Most light sources are operated from line power, but some may be powered from batteries. They are mostly used in endoscopic, microscopic, and other examination and/or in surgical procedures. The light source is part of the optical subsystem. In a flow cytometer the light source directs high intensity light at particles at the interrogation point. The light source in a flow cytometer is usually a laser.
http://purl.obolibrary.org/obo/OBI_0400078 obscuration bar http://purl.obolibrary.org/obo/OBI_0000932 material separation device An obscuration bar is a an optical subsystem which is a strip of metal or other material that serves to block out direct light from the illuminating beam. The obscuration bar prevents the bright light scattered in the forward directions from burning out the collection device.
http://purl.obolibrary.org/obo/OBI_0400079 optical filter http://purl.obolibrary.org/obo/OBI_0000932 material separation device An optical filter is an optical subsystem that selectively transmits light having certain properties (often, a particular range of wavelengths, that is, range of colours of light), while blocking the remainder. They are commonly used in photography, in many optical instruments, and to colour stage lighting Optical filters can be arranged to segregate and collect light by wave length.
http://purl.obolibrary.org/obo/OBI_0400082 photodetector http://purl.obolibrary.org/obo/OBI_0000832 measurement device A photodetector is a device used to detect and measure the intensity of radiant energy through photoelectric action. In a cytometer, photodetectors measure either the number of photons of laser light scattered on impact with a cell (for example), or the flourescence emitted by excitation of a fluorescent dye.
http://purl.obolibrary.org/obo/OBI_0400103 DNA sequencer http://purl.obolibrary.org/obo/OBI_0000832 measurement device A DNA sequencer is an instrument that determines the order of deoxynucleotides in deoxyribonucleic acid sequences.
http://purl.obolibrary.org/obo/OBI_0400110 hybridization chamber http://purl.obolibrary.org/obo/OBI_0001034 environmental control device A device which is used to maintain constant contact of a liquid on an array. This can be either a glass vial or slide.
http://purl.obolibrary.org/obo/OBI_0400137 cytometer http://purl.obolibrary.org/obo/OBI_0000832 measurement device A cytometer is an instrument for counting and measuring cells.
http://purl.obolibrary.org/obo/OBI_0400147 microarray http://purl.obolibrary.org/obo/OBI_0001865 assay array A processed material that is made to be used in an analyte assay. It consists of a physical immobilisation matrix in which substances that bind the analyte are placed in regular spatial position.
http://purl.obolibrary.org/obo/OBI_0500002 repeated measure design http://purl.obolibrary.org/obo/OBI_0500000 study design a study design which use the same individuals and exposure them to a set of conditions. The effect of order and practice can be confounding factor in such designs
http://purl.obolibrary.org/obo/OBI_0500003 cross over design http://purl.obolibrary.org/obo/STATO_0000046 block design a repeated measure design which ensures that experimental units receive, in sequence, the treatment (or the control), and then, after a specified time interval (aka *wash-out periods*), switch to the control (or treatment). In this design, subjects (patients in human context) serve as their own controls, and randomization may be used to determine the ordering which a subject receives the treatment and control
http://purl.obolibrary.org/obo/OBI_0500005 matched pairs design http://purl.obolibrary.org/obo/STATO_0000046 block design A matched pair design is a study design which use groups of individuals associated (hence matched) to each other based on a set of criteria, one member going to one treatment, the other member receiving the other treatment.
http://purl.obolibrary.org/obo/OBI_0500007 randomized complete block design http://purl.obolibrary.org/obo/STATO_0000046 block design A randomized complete block design is_a study design which assigns randomly treatments to block. The number of units per block equals the number of treatment so each block receives each treatment exactly once (hence the qualifier 'complete'). The design was originally devised from field trials used in agronomy and agriculture. The analysis assumes that there is no interaction between block and treatment. The method was then used in other settings So The randomised complete block design is a design in which the subjects are matched according to a variable which the experimenter wishes to control. The subjects are put into groups (blocks) of the same size as the number of treatments. The members of each block are then randomly assigned to different treatment groups.
http://purl.obolibrary.org/obo/OBI_0500011 latin square design http://purl.obolibrary.org/obo/OBI_0500007 randomized complete block design Latin square design is_a study design which allows in its simpler form controlling 2 levels of nuisance variables (also known as blocking variables). The 2 nuisance factors are divided into a tabular grid with the property that each row and each column receive each treatment exactly once.
http://purl.obolibrary.org/obo/OBI_0500012 graeco latin square design http://purl.obolibrary.org/obo/STATO_0000222 graeco-latin square design graeco-latin square design is a block design which declares 3 blocking variables (aka nuisance variables) in addition to the treatment variable
http://purl.obolibrary.org/obo/OBI_0500013 hyper graeco latin square design http://purl.obolibrary.org/obo/OBI_0500007 randomized complete block design hyper graeco-latin square design is a block design which declares 4 blocking variables (aka nuisance variables) in addition to the treatment variable
http://purl.obolibrary.org/obo/OBI_0500014 factorial design http://purl.obolibrary.org/obo/OBI_0500000 study design factorial design is_a study design which is used to evaluate two or more factors simultaneously. The treatments are combinations of levels of the factors. The advantages of factorial designs over one-factor-at-a-time experiments is that they are more efficient and they allow interactions to be detected. In statistics, a factorial design experiment is an experiment whose design consists of two or more factors, each with discrete possible values or levels, and whose experimental units take on all possible combinations of these levels across all such factors. Such an experiment allows studying the effect of each factor on the response variable, as well as the effects of interactions between factors on the response variable.
http://purl.obolibrary.org/obo/OBI_0500015 2x2 factorial design http://purl.obolibrary.org/obo/STATO_0000270 full factorial design a factorial design which has 2 experimental factors (aka independent variables) and 2 factor levels per experimental factors
http://purl.obolibrary.org/obo/OBI_0500016 fractional factorial design http://purl.obolibrary.org/obo/OBI_0500014 factorial design A fractional factorial design is_a study design in which only an adequately chosen fraction of the treatment combinations required for the complete factorial experiment is selected to be run
http://purl.obolibrary.org/obo/OBI_0500017 dye swap design http://purl.obolibrary.org/obo/STATO_0000046 block design An experiment design type where the label orientations are reversed. exact synonym: flip dye, dye flip
http://purl.obolibrary.org/obo/OBI_0500020 time series design http://purl.obolibrary.org/obo/OBI_0500000 study design Groups of assays that are related as part of a time series.
http://purl.obolibrary.org/obo/OBI_0600005 collecting specimen from organism http://purl.obolibrary.org/obo/OBI_0000659 specimen collection a process with the objective to obtain a material entity that was part of an organism for potential future use in an investigation
http://purl.obolibrary.org/obo/OBI_0600014 material component separation http://purl.obolibrary.org/obo/OBI_0000094 material processing a material processing in which components of an input material become segregated in space
http://purl.obolibrary.org/obo/OBI_0600024 maintaining cell culture http://purl.obolibrary.org/obo/OBI_0000838 material maintenance a protocol application in which cells are kept alive in a defined environment outside of an organism. part of cell_culturing
http://purl.obolibrary.org/obo/OBI_0600036 establishing cell culture http://purl.obolibrary.org/obo/OBI_0000094 material processing a process through which a new type of cell culture or cell line is created, either through the isolation and culture of one or more cells from a fresh source, or the deliberate experimental modification of an existing cell culture (e.g passaging a primary culture to become a secondary culture or line, or the immortalization or stable genetic modification of an existing culture or line).
http://purl.obolibrary.org/obo/OBI_0600047 sequencing assay http://purl.obolibrary.org/obo/OBI_0000070 assay the use of a chemical or biochemical means to infer the sequence of a biomaterial
http://purl.obolibrary.org/obo/OBI_0666667 nucleic acid extraction http://purl.obolibrary.org/obo/OBI_0302884 extraction a material separation to recover the nucleic acid fraction of an input material
http://purl.obolibrary.org/obo/OBI_1110108 material to be added http://purl.obolibrary.org/obo/BFO_0000040 material entity a material that is added to another one in a material combination process
http://purl.obolibrary.org/obo/OBI_1110109 target of material addition http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity into which another is being added in a material combinatino process
http://purl.obolibrary.org/obo/OGMS_0000023 phenotype http://purl.obolibrary.org/obo/BFO_0000019 quality A (combination of) quality(ies) of an organism determined by the interaction of its genetic make-up and environment that differentiates specific instances of a species from other instances of the same species.
http://purl.obolibrary.org/obo/PR_000000001 protein http://purl.obolibrary.org/obo/CHEBI_16670 peptide An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA.
http://purl.obolibrary.org/obo/UO_0000001 length unit http://purl.obolibrary.org/obo/IAO_0000003 measurement unit label A unit which is a standard measure of the distance between two points.
http://purl.obolibrary.org/obo/UO_0000003 time unit http://purl.obolibrary.org/obo/IAO_0000003 measurement unit label A unit which is a standard measure of the dimension in which events occur in sequence.
http://purl.obolibrary.org/obo/STATO_0000017 Wilk's lambda distribution http://purl.obolibrary.org/obo/STATO_0000225 probability distribution Wilks' lambda distribution (named for Samuel S. Wilks), is a probability distribution used in multivariate hypothesis testing, especially with regard to the likelihood-ratio test and Multivariate analysis of variance. It is a multivariate generalization of the univariate F-distribution, and generalizes the F-distribution in the same way that the Hotelling's T-squared distribution generalizes Student's t-distribution.
http://purl.obolibrary.org/obo/STATO_0000057 null hypothesis http://purl.obolibrary.org/obo/STATO_0000065 hypothesis A null hypothesis is a statistical hypothesis that is tested for possible rejection under the assumption that it is true (usually that observations are the result of chance). The concept was introduced by R. A. Fisher.
The hypothesis contrary to the null hypothesis, usually that the observations are the result of a real effect, is known as the alternative hypothesis.[wolfram alpha]
http://purl.obolibrary.org/obo/STATO_0000060 hypergeometric distribution http://purl.obolibrary.org/obo/STATO_0000117 discrete probability distribution hypergeometric distribution is a probability distribution that describes the probability of k successes in n draws from a finite population of size N containing K successes without replacement
http://purl.obolibrary.org/obo/STATO_0000066 Cleveland dot plot http://purl.obolibrary.org/obo/IAO_0000037 dot plot Cleveland dot plot is a dot plot which plots points that each belong to one of several categories. They are an alternative to bar charts or pie charts, and look somewhat like a horizontal bar chart where the bars are replaced by a dots at the values associated with each category. Compared to (vertical) bar charts and pie charts, Cleveland argues that dot plots allow more accurate interpretation of the graph by readers by making the labels easier to read, reducing non-data ink (or graph clutter) and supporting table look-up.which
http://purl.obolibrary.org/obo/STATO_0000075 rarefaction curve http://purl.obolibrary.org/obo/IAO_0000573 line graph a rarefaction curve is a graph used for estimating species richness in ecology studies
http://purl.obolibrary.org/obo/STATO_0000103 multinomial distribution http://purl.obolibrary.org/obo/STATO_0000117 discrete probability distribution the multinomial distribution is a probability distribution which gives the probability of any particular combination of numbers of successes for various categories defined in the context of n independent trials each of which leads to a success for exactly one of k categories, with each category having a given fixed success probability.
http://purl.obolibrary.org/obo/STATO_0000112 Funnel plot http://purl.obolibrary.org/obo/IAO_0000184 scatter plot a Funnel plot is a scatter plot of treatment effect versus a measure of study size and aims to provide a visual aid to detecting bias or systematic heterogeneity. A symmetric inverted funnel shape arises from a ‘well-behaved’ data set, in which publication bias is unlikely. An asymmetric funnel indicates a relationship between treatment effect and study size.
Known caveats: If high precision studies really are different from low precision studies with respect to effect size (e.g., due to different populations examined) a funnel plot may give a wrong impression of publication bias. The appearance of the funnel plot can change quite dramatically depending on the scale on the y-axis — whether it is the inverse square error or the trial size.
Funnel plot was introduced by Light and Palmer in 1984.
http://purl.obolibrary.org/obo/STATO_0000120 bean plot http://purl.obolibrary.org/obo/IAO_0000038 graph beanplot is a plot in which (one or) multiple batches ("beans") are shown. Each bean consists of a density trace, which is mirrored to
form a polygon shape. Next to that, a one-dimensional scatter plot shows all the individual measurements, like in a stripchart.
The name beanplot stems from green beans. The density shape can be seen as the pod of a green bean, while the scatter plot shows the seeds inside the pod.
http://purl.obolibrary.org/obo/STATO_0000122 pedigree chart http://purl.obolibrary.org/obo/IAO_0000038 graph a pedigree chart is a graph which plots parent child relations
http://purl.obolibrary.org/obo/STATO_0000125 Wilkinson dot plot http://purl.obolibrary.org/obo/IAO_0000037 dot plot The dot plot as a representation of a distribution consists of group of data points plotted on a simple scale. Dot plots are used for continuous, quantitative, univariate data. Data points may be labelled if there are few of them.
http://purl.obolibrary.org/obo/STATO_0000126 volcano plot http://purl.obolibrary.org/obo/IAO_0000184 scatter plot volcano plot is a kind of scatter plot which graphs the negative log of the p-value (significance) on the y-axis versus log2 of fold-change between 2 conditions on the x-axis.
It is a popular method for visualizing differential occurence of variables between 2 conditions.
http://purl.obolibrary.org/obo/STATO_0000128 Altman box and whisker plot http://purl.obolibrary.org/obo/STATO_0000243 box and whisker plot Altman Box and Whisker plot is a variation of Tukey Box and Whisker plot which use the criteria of Altman to create the 'whisker' of the plot.
http://purl.obolibrary.org/obo/STATO_0000132 Hotelling T2 distribution http://purl.obolibrary.org/obo/STATO_0000225 probability distribution Hotelling T squared distribution is a probability distribution used in multivariate hypothesis testing, which is a univariate distribution proportional to the F-distribution and arises importantly as the distribution of a set of statistics which are natural generalizations of the statistics underlying Student's t-distribution.
In particular, the distribution arises in multivariate statistics in undertaking tests of the differences between the (multivariate) means of different populations, where tests for univariate problems would make use of a t-test.
The distribution is named for Harold Hotelling, who developed it[1] as a generalization of Student's t-distribution.
This distribution is commonly used to describe the sample Mahalanobis distance between two populations.
http://purl.obolibrary.org/obo/STATO_0000145 geometric distribution http://purl.obolibrary.org/obo/STATO_0000283 negative binomial distribution the geometric distribution is a negative binomial distribution where r is 1.
It is useful for modeling the runs of consecutive successes (or failures) in repeated independent trials of a system.
The geometric distribution models the number of successes before one failure in an independent succession of tests where each test results in success or failure.
The geometric distribution with prob = p has density
p(x) = p (1-p)^x
for x = 0, 1, 2, …, 0 < p ≤ 1.
If an element of x is not integer, the result of dgeom is zero, with a warning.
The quantile is defined as the smallest value x such that F(x) ≥ p, where F is the distribution function.
http://purl.obolibrary.org/obo/STATO_0000147 LD plot http://purl.obolibrary.org/obo/IAO_0000038 graph Linkage Disequilibrium plot is a graph which represents pairwise linkage disequilibrium measures between SNP as a heatmap
http://purl.obolibrary.org/obo/STATO_0000154 violin plot http://purl.obolibrary.org/obo/IAO_0000038 graph a violin plot is a plot combining the features of box plot and kernel density plot. The violin plot is therefore similar to box plot but it incorporated in the display the probability density of the data at different values.
Typically violin plots will include a marker for the median of the data and a box indicating the interquartile range, as in standard box plots.
http://purl.obolibrary.org/obo/STATO_0000159 stacked bar chart http://purl.obolibrary.org/obo/STATO_0000166 bar chart Stacked bar chart is a bar which is used to compare overall quantities across items while showing the contribution of category to the total amount. Stacked bar chart can be used for highlighting the total as they visually aggregate all of the categories in a group while indicating a part to whole relationship. The downside is that it becomes harder to compare the sizes of the individual categories.
http://purl.obolibrary.org/obo/STATO_0000165 pie chart http://purl.obolibrary.org/obo/IAO_0000038 graph a pie chart is a graph in which a circular graph is divided into sector illustrating numerical proportion, meaning that the arc length of each sector (and consequently its central angle and area), is proportional to the quantity it represents.
http://purl.obolibrary.org/obo/STATO_0000166 bar chart http://purl.obolibrary.org/obo/IAO_0000038 graph the bart chart is a graph resulting from plotting rectangular bars with lengths proportional to the values that they represent.
http://purl.obolibrary.org/obo/STATO_0000168 real time quantitative pcr plot http://purl.obolibrary.org/obo/IAO_0000573 line graph a real time quantitative pcr plot is a line graph which plots the signal fluorescence intensity as a function of the number of PCR cycle
http://purl.obolibrary.org/obo/STATO_0000171 Spear box and whisker plot http://purl.obolibrary.org/obo/STATO_0000243 box and whisker plot Spear Box and Whisker plot is a variation of Tukey Box and Whisker plot which use the criteria of Spear to create the 'whisker' of the plot.
http://purl.obolibrary.org/obo/STATO_0000174 Forest plot http://purl.obolibrary.org/obo/IAO_0000038 graph A forest plot is a graph designed to illustrate the relative strength of treatment effects in multiple quantitative scientific studies addressing the same question.
http://purl.obolibrary.org/obo/STATO_0000177 beta distribution http://purl.obolibrary.org/obo/STATO_0000067 continuous probability distribution the beta distribution is a continuous probability distributions defined on the interval [0, 1] parametrized by two positive shape parameters, denoted by α and β, that appear as exponents of the random variable and control the shape of the distribution
http://purl.obolibrary.org/obo/STATO_0000180 standard normal distribution http://purl.obolibrary.org/obo/STATO_0000227 normal distribution standard normal distribution is a normal distribution with variance = 1 and mean=0
http://purl.obolibrary.org/obo/STATO_0000186 Lineweaver-Burk plot http://purl.obolibrary.org/obo/IAO_0000038 graph Lineweaver-Burk plot is a graph which is the graphical representation of the Lineweaver–Burk equation of enzyme kinetics, described by Hans Lineweaver and Dean Burk in 1934. The plot provides a useful graphical method for analysis of the Michaelis–Menten equation.
It was widely used to determine important terms in enzymology and enzyme kinetics as the x-intercept of the graph represents −1/Km and the y-intercept of such a graph is equivalent to the inverse of Vmax
http://purl.obolibrary.org/obo/STATO_0000219 RT-PCR standard curve http://purl.obolibrary.org/obo/IAO_0000573 line graph a real time pcr standard curve is a line graph which plots the fluorescence intensity signal as a function of the concentration of a sample used as reference and used to determine relative abundance of test samples
http://purl.obolibrary.org/obo/STATO_0000241 Q-Q plot http://purl.obolibrary.org/obo/IAO_0000038 graph Q-Q plot or quantile-quantile plot is the output of a graphical method for comparing two probability distributions by plotting their quantiles against each other
http://purl.obolibrary.org/obo/STATO_0000256 manhattan plot for gwas http://purl.obolibrary.org/obo/IAO_0000184 scatter plot a manhattan plot for gwas is a kind of scatter plot used to facilitate presentation of genome-wide association study (GWAS) data. Genomic coordinates are displayed along the X-axis, with the negative logarithm of the association P-value for each single nucleotide polymorphism displayed on the Y-axis.
http://purl.obolibrary.org/obo/STATO_0000262 Bernoulli distribution http://purl.obolibrary.org/obo/STATO_0000276 binomial distribution Bernoulli distribution is a binomial distribution where the number of trials is equal to 1.
notation: B(1,p)
The mean is p
The variance is p*q
http://purl.obolibrary.org/obo/STATO_0000263 Galbraith plot http://purl.obolibrary.org/obo/IAO_0000184 scatter plot Galbraith (Radial) plot is a scatter plot which can be used in the meta-analytic context to examine the data for heterogeneity. For a fixed-effects model, the plot shows the inverse of the standard errors on the horizontal axis against the individual observed effect sizes or outcomes standardized by their corresponding standard errors on the vertical axis.
Radial plots were introduced by Rex Galbraith (1988a, 1988b, 1994).
http://purl.obolibrary.org/obo/STATO_0000267 grouped bar chart http://purl.obolibrary.org/obo/STATO_0000166 bar chart grouped bar chart is a kind of bar chart which juxtaposes the discrete values for each of the possible value of a given categorical variable, thus providing within group comparison. Grouped bar charts are good for comparing between each element in the categories, and comparing elements across categories. However, the grouping can make it harder to tell the difference between the total of each group.
http://purl.obolibrary.org/obo/STATO_0000274 receiver operational characteristics curve http://purl.obolibrary.org/obo/IAO_0000038 graph receiver operational characteristics curve is a graphical plot which illustrates the performance of a binary classifier system as its discrimination threshold (aka cut-off point) is varied by plotting sensitivity vs (1 − specificity)
http://purl.obolibrary.org/obo/CHEBI_16991 deoxyribonucleic acid http://purl.obolibrary.org/obo/CHEBI_33696 nucleic acid High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms.
http://purl.obolibrary.org/obo/CHEBI_33696 nucleic acid http://purl.obolibrary.org/obo/CHEBI_33839 macromolecule A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid.
http://purl.obolibrary.org/obo/CL_0000000 cell http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.
http://purl.obolibrary.org/obo/CL_0000010 cultured cell http://purl.obolibrary.org/obo/CL_0000578 experimentally modified cell in vitro A cell in vitro that is or has been maintained or propagated as part of a cell culture.
http://purl.obolibrary.org/obo/CL_0000578 experimentally modified cell in vitro http://purl.obolibrary.org/obo/CL_0000000 cell A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure.
http://purl.obolibrary.org/obo/CHEBI_16670 peptide http://purl.obolibrary.org/obo/CHEBI_33839 macromolecule Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc.
http://purl.obolibrary.org/obo/CHEBI_33697 ribonucleic acid http://purl.obolibrary.org/obo/CHEBI_33696 nucleic acid High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins.
http://purl.obolibrary.org/obo/STATO_0000209 area under curve http://purl.obolibrary.org/obo/IAO_0000109 measurement data item area under curve is a measurement datum which corresponds to the surface define by the x-axis and bound by the line graph represented in a 2 dimensional plot resulting from an integration or integrative calculus. The interpretation of this measurement datum depends on the variables plotted in the graph
http://purl.obolibrary.org/obo/STATO_0000009 cartesian coordinate system http://purl.obolibrary.org/obo/STATO_0000010 coordinate system A Cartesian coordinate system is a coordinate system that specifies each point uniquely in a plane by a pair of numerical coordinates, which are the signed distances from the point to two fixed perpendicular directed lines, measured in the same unit of length.
http://purl.obolibrary.org/obo/STATO_0000010 coordinate system http://purl.obolibrary.org/obo/IAO_0000030 information content entity In geometry, a coordinate system is a system which uses one or more numbers, or coordinates, to uniquely determine the position of a point or other geometric element on a manifold such as Euclidean space.
http://purl.obolibrary.org/obo/STATO_0000013 two dimensional cartesian coordinate system http://purl.obolibrary.org/obo/STATO_0000009 cartesian coordinate system a 2 dimensional cartesian coordinate system is a cartesian coordinate system which defines 2 orthogonal one dimensional axes and which may be used to describe a 2 dimensional spatial region
http://purl.obolibrary.org/obo/STATO_0000014 spherical coordinate system http://purl.obolibrary.org/obo/STATO_0000010 coordinate system In mathematics, a spherical coordinate system is a coordinate system for three-dimensional space where the position of a point is specified by three numbers: the radial distance of that point from a fixed origin, its polar angle measured from a fixed zenith direction, and the azimuth angle of its orthogonal projection on a reference plane that passes through the origin and is orthogonal to the zenith, measured from a fixed reference direction on that plane.
http://purl.obolibrary.org/obo/STATO_0000015 cylindrical coordinate system http://purl.obolibrary.org/obo/STATO_0000010 coordinate system A cylindrical coordinate system is a three-dimensional coordinate system that specifies point positions by the distance from a chosen reference axis, the direction from the axis relative to a chosen reference direction, and the distance from a chosen reference plane perpendicular to the axis. The latter distance is given as a positive or negative number depending on which side of the reference plane faces the point.
http://purl.obolibrary.org/obo/STATO_0000016 polar coordinate system http://purl.obolibrary.org/obo/STATO_0000010 coordinate system In mathematics, the polar coordinate system is a two-dimensional coordinate system in which each point on a plane is determined by a distance from a fixed point and an angle from a fixed direction.
http://purl.obolibrary.org/obo/STATO_0000022 one dimensional cartesian coordinate system http://purl.obolibrary.org/obo/STATO_0000009 cartesian coordinate system a three dimensional cartesian coordinate system is a cartesian coordinate system which defines 3 orthogonal one dimensional axis and which may be used to describe a 3 dimensional spatial region
http://purl.obolibrary.org/obo/STATO_0000024 three dimensional cartesian coordinate system http://purl.obolibrary.org/obo/STATO_0000009 cartesian coordinate system a three dimensional cartesian coordinate system is a cartesian coordinate system which defines 3 orthogonal one dimensional axes and which may be used to describe a 3 dimensional spatial region
http://purl.obolibrary.org/obo/STATO_0000047 count http://purl.obolibrary.org/obo/IAO_0000109 measurement data item a count is a data item denoted by an integer and represented the number of instances or occurences of an entity
http://purl.obolibrary.org/obo/STATO_0000050 signal to noise ratio http://purl.obolibrary.org/obo/STATO_0000184 ratio signal to noise ratio is a measurement datum comparing the amount of meaningful, useful or interesting data (the signal) to the amount of irrelevant or false data (the noise). Depending on the field and domain of application, different variables will be used to determinate a 'signal to noise ratio'. In statistics, the definition of signal to noise ratio is the ratio of the mean of a measurement to its standard deviation. It thus corresponds to the inverse of the coefficient of variation
http://purl.obolibrary.org/obo/STATO_0000053 false positive rate http://purl.obolibrary.org/obo/STATO_0000300 dimensionless ratio a false positive rate is a data item which accounts for the proportion of incorrect rejection of a true null hypothesis.
http://purl.obolibrary.org/obo/STATO_0000055 chromosome coordinate system http://purl.obolibrary.org/obo/STATO_0000197 genomic coordinate system chromosome coordinate system is a genomic coordinate which uses chromosome of a particular assembly build process to define start and end positions. This coordinate system is unstable and will change with each new genome sequence assembly build.
http://purl.obolibrary.org/obo/STATO_0000064 sequence read count http://purl.obolibrary.org/obo/STATO_0000047 count sequence read count is a data item determining how many sequence reads generated by a DNA sequencing assay for a given stretch of DNA can counted
http://purl.obolibrary.org/obo/STATO_0000069 number of degrees of freedom http://purl.obolibrary.org/obo/STATO_0000047 count The number degree of freedom is a count evaluating the number of values in a calculation that can vary. In statistics, the number of degrees of freedom ν is equal to N-1 in the case of the direct measurement of a quantity estimated by the arithmetic mean of N independent observations.
http://purl.obolibrary.org/obo/STATO_0000071 reaction rate http://purl.obolibrary.org/obo/STATO_0000184 ratio reaction rate is a measurement datum which represents the speed of a chemical reaction turning reactive species into product species of event (i.e the number of such conversions)s occuring over a time interval
http://purl.obolibrary.org/obo/STATO_0000087 polychotomous variable http://purl.obolibrary.org/obo/STATO_0000252 categorical variable a polychotomous variable is a categorical variable which is defined to have minimally 2 categories or possible values
http://purl.obolibrary.org/obo/STATO_0000090 dichotomous variable http://purl.obolibrary.org/obo/STATO_0000087 polychotomous variable a dichotomous variable is a categorical variable which is defined to have only 2 categories or possible values
http://purl.obolibrary.org/obo/STATO_0000169 fold change http://purl.obolibrary.org/obo/STATO_0000300 dimensionless ratio Fold change is a number describing how much a quantity changes going from an initial to a final value or one condition to another condition
http://purl.obolibrary.org/obo/STATO_0000182 odds ratio http://purl.obolibrary.org/obo/STATO_0000085 effect size estimate Odds ratio is a ratio that measures effect size, that is the strength of association between 2 dichotomous variables, one describing an exposure and one describing an outcome.
It represents the odds that an outcome will occur given a particular exposure, compared to the odds of the outcome occurring in the absence of that exposure ( the probability of the event occuring divided by the probability of an event not occurring). The odds ratio is a ratio of describing the strength of association or non-independence between two binary data values by forming the ratio of the odds for the first group and the odds for the second group. Odds ratio are used when one wants to compare the odds of something occurring to two different groups.
http://purl.obolibrary.org/obo/STATO_0000184 ratio http://purl.obolibrary.org/obo/IAO_0000027 data item A ratio is a data item which is formed with two numbers r and s is written r/s, where r is the numerator and s is the denominator. The ratio of r to s is equivalent to the quotient r/s.
http://purl.obolibrary.org/obo/STATO_0000197 genomic coordinate system http://purl.obolibrary.org/obo/STATO_0000010 coordinate system a genomic coordinate system is a coordinate system to describe position of sequence on a genomic scaffold (assembly of chromosome, contig....)
http://purl.obolibrary.org/obo/STATO_0000210 channel1/channel2 fluorescence intensity ratio http://purl.obolibrary.org/obo/STATO_0000169 fold change is a data item formed by dividing the fluorescence intensity obtained in one channel to that obtained in the other channel, typically the case when considering 2-color microarray data when imaging is done for Cy3 and Cy5 dyes.
http://purl.obolibrary.org/obo/STATO_0000220 false negative rate http://purl.obolibrary.org/obo/STATO_0000300 dimensionless ratio the false negative rate is a data item which denotes the proportion of missed detection of elements known to be meeting the detection criteria
http://purl.obolibrary.org/obo/STATO_0000232 number of PCR cycle http://purl.obolibrary.org/obo/STATO_0000047 count number of PCR cycle is a count which enumerates how many iterations of 'annealing, renaturation, amplification,' rounds (or cycles) are performed during a polymerase chain reaction (PCR) or an assay relying on PCR.
http://purl.obolibrary.org/obo/STATO_0000251 continuous variable http://purl.obolibrary.org/obo/STATO_0000258 variable A continuous variable is one for which, within the limits the variable ranges, any value is possible.
http://purl.obolibrary.org/obo/STATO_0000254 allele frequency http://purl.obolibrary.org/obo/STATO_0000184 ratio The allele frequency is a data item which denotes the incidence of a gene variant in a population. It is calculated as a ratio, by dividing the number of copies of a particular allele by the number of copies of all alleles at the genetic place (locus) in a population.
http://purl.obolibrary.org/obo/STATO_0000258 variable http://purl.obolibrary.org/obo/IAO_0000033 directive information entity a variable is a data item which can assume any of a set of values, either as determined by an agent or as randomly occuring through observation.
http://purl.obolibrary.org/obo/STATO_0000300 dimensionless ratio http://purl.obolibrary.org/obo/STATO_0000184 ratio A ratio where the numerator and denominator are expressed in the same unit.
http://purl.obolibrary.org/obo/STATO_0000002 digital file http://purl.obolibrary.org/obo/IAO_0000030 information content entity an electronic file is an information content entity which conforms to a specification or format and which is meant to hold data and information in digital form, accessible to software agents
http://purl.obolibrary.org/obo/STATO_0000003 balanced design http://purl.obolibrary.org/obo/OBI_0500000 study design a balanced design is a an experimental design where all experimental group have the an equal number of subject observations
http://purl.obolibrary.org/obo/STATO_0000005 single factor design http://purl.obolibrary.org/obo/OBI_0500000 study design a single factor design is a study design which declares exactly 1 independent variable
http://purl.obolibrary.org/obo/STATO_0000006 x-axis http://purl.obolibrary.org/obo/STATO_0000011 cartesian coordinate axis x-axis is a cartesian coordinate axis which is orthogonal to the y-axis and the z-axis
http://purl.obolibrary.org/obo/STATO_0000007 axis http://purl.obolibrary.org/obo/IAO_0000573 line graph an axis is a line graph used as reference line for the measurement of coordinates.
http://purl.obolibrary.org/obo/STATO_0000008 y-axis http://purl.obolibrary.org/obo/STATO_0000011 cartesian coordinate axis y-axis is a cartesian coordinate axis which is orthogonal to the x-axis and the z-axis
http://purl.obolibrary.org/obo/STATO_0000012 z-axis http://purl.obolibrary.org/obo/STATO_0000011 cartesian coordinate axis z-axis is a cartesian coordinate axis which is orthogonal to the x-axis and the y-axis
http://purl.obolibrary.org/obo/STATO_0000018 three dimensional cartesian spatial coordinate origin http://purl.obolibrary.org/obo/STATO_0000026 cartesian spatial coordinate origin A cartesian spatial coordinate datum chosen as a fixed point of reference in a three dimensional spatial region.
http://purl.obolibrary.org/obo/STATO_0000019 normal distribution hypothesis http://purl.obolibrary.org/obo/STATO_0000058 goodness of fit hypothesis normal distribution hypothesis is a goodness of fit hypothesis stating that the distribution computed from the sample population fits a normal distribution
http://purl.obolibrary.org/obo/STATO_0000020 two dimensional cartesian spatial coordinate origin http://purl.obolibrary.org/obo/STATO_0000026 cartesian spatial coordinate origin A cartesian spatial coordinate datum chosen as a fixed point of reference in a two dimensional spatial region.
http://purl.obolibrary.org/obo/STATO_0000021 90% confidence interval http://purl.obolibrary.org/obo/STATO_0000196 confidence interval a confidence interval which covers 90% of the sampling distribution, meaning that there is a 90% risk of false positive (type I error)
http://purl.obolibrary.org/obo/STATO_0000025 one dimensional cartesian spatial coordinate origin http://purl.obolibrary.org/obo/STATO_0000026 cartesian spatial coordinate origin A cartesian spatial coordinate datum chosen as a fixed point of reference in a one dimensional spatial region.
http://purl.obolibrary.org/obo/STATO_0000026 cartesian spatial coordinate origin http://purl.obolibrary.org/obo/IAO_0000400 cartesian spatial coordinate datum A cartesian spatial coordinate datum chosen as a fixed point of reference in a spatial region.
http://purl.obolibrary.org/obo/STATO_0000028 measure of variation http://purl.obolibrary.org/obo/IAO_0000109 measurement data item measure of variation or statistical dispersion is a data item which describes how much a theoritical distribution or dataset is spread.
http://purl.obolibrary.org/obo/STATO_0000029 measure of central tendency http://purl.obolibrary.org/obo/IAO_0000109 measurement data item a measure of central tendency is a data item which attempts to describe a set of data by identifying the value of its centre.
http://purl.obolibrary.org/obo/STATO_0000030 Chi-Squared statistic http://purl.obolibrary.org/obo/STATO_0000039 statistic Chi-squared statistic is a statistic computed from observations and used to produce a p-value in statistical test when compared to a Chi-Squared distribution.
http://purl.obolibrary.org/obo/STATO_0000031 binary classification http://purl.obolibrary.org/obo/OBI_0200000 data transformation binary classification (or binomial classification) is a data transformation which aims to cast members of a set into 2 disjoint groups depending on whether the element have a given property/feature or not.
http://purl.obolibrary.org/obo/STATO_0000033 mode http://purl.obolibrary.org/obo/STATO_0000029 measure of central tendency The mode is a data item which corresponds to the most frequently occurring number in a set of numbers.
http://purl.obolibrary.org/obo/STATO_0000034 model parameter http://purl.obolibrary.org/obo/IAO_0000027 data item a model parameter is a data item which is part of a model and which is meant to characterize an theoritecal or unknown population. a model parameter may be estimated by considering the properties of samples presumably taken from the theoritecal population
http://purl.obolibrary.org/obo/STATO_0000035 range http://purl.obolibrary.org/obo/STATO_0000028 measure of variation the range is a measure of variation which describes the difference between the lowest score and the highest score in a set of numbers (a data set)
http://purl.obolibrary.org/obo/STATO_0000036 outlier http://purl.obolibrary.org/obo/IAO_0000027 data item Outliers are deviant scores that have been legitimately gathered and are not due to equipment failures.
http://purl.obolibrary.org/obo/STATO_0000038 matched pair of subjects http://purl.obolibrary.org/obo/OBI_0000181 population a set of 2 subjects which result from a pairing process which assigns subject to a set based on a pairing rule/criteria
http://purl.obolibrary.org/obo/STATO_0000039 statistic http://purl.obolibrary.org/obo/IAO_0000109 measurement data item a statistic is a measurement datum to describe a dataset or a variable. It is generated by a calculation on set of observed data.
http://purl.obolibrary.org/obo/STATO_0000042 Anderson-Darling test http://purl.obolibrary.org/obo/STATO_0000191 goodness of fit statistical test The Anderson–Darling test is a statistical test of whether a given sample of data is drawn from a given probability distribution.
http://purl.obolibrary.org/obo/STATO_0000046 block design http://purl.obolibrary.org/obo/OBI_0500000 study design a block design is a kind of study design which declares a blocking variable (also known as nuisance variable) in order to account for a known source of variation and reduce its impact on the acquisition of the signal
http://purl.obolibrary.org/obo/STATO_0000048 multiway ANOVA http://purl.obolibrary.org/obo/OBI_0200201 ANOVA Multi-way anova is an analysis of variance where the difference groups being compared are associated to the factor levels of more than 2 independent variables. The null hypothesis is an absence of difference between the means calculated for each of the groups. The test assumes normality and equivariance of the data.
http://purl.obolibrary.org/obo/STATO_0000049 Hardy-Weinberg equilibrium hypothesis http://purl.obolibrary.org/obo/STATO_0000058 goodness of fit hypothesis Hardy-Weinberg equilibrium hypothesis is a good of fit hypothesis which states that allele and genotype frequencies in a population will remain constant from generation to generation in the absence of other evolutionary influences (non-random mating, mutation, selection, genetic drift, gene flow and meiotic drive).
http://purl.obolibrary.org/obo/STATO_0000051 Poisson distribution http://purl.obolibrary.org/obo/STATO_0000117 discrete probability distribution Poisson distribution is a probability distribution used to model the number of events occurring within a given time interval. It is defined by a real number (λ) and an integer k representing the number of events and a function.
The expected value of a Poisson-distributed random variable is equal to λ and so is its variance.
http://purl.obolibrary.org/obo/STATO_0000052 Z-test http://purl.obolibrary.org/obo/STATO_0000279 between group comparison statistical test Z-test is a statistical test which evaluate the null hypothesis that the means of 2 populations are equal and returns a p-value.
http://purl.obolibrary.org/obo/STATO_0000056 absence of association hypothesis http://purl.obolibrary.org/obo/STATO_0000065 hypothesis a null hypothesis which states that no linkage exists between 2 categorical variables
http://purl.obolibrary.org/obo/STATO_0000058 goodness of fit hypothesis http://purl.obolibrary.org/obo/STATO_0000065 hypothesis goodness of fit hypothesis is a null hypothesis stating that the distribution computed from the sample population fits a theoretical distribution or that a dataset can be correctly explained by a model
http://purl.obolibrary.org/obo/STATO_0000059 Student's t distribution http://purl.obolibrary.org/obo/STATO_0000329 symmetric distribution the Student's t distribution is a continuous probability distribution which arises when estimating the mean of a normally distributed population in situations where the sample size is small and population standard deviation is unknown.
http://purl.obolibrary.org/obo/STATO_0000061 absence of between group difference hypothesis http://purl.obolibrary.org/obo/STATO_0000065 hypothesis It is a null hypothesis stating that there are no differences observed between group of subjects.
http://purl.obolibrary.org/obo/STATO_0000062 absence of within subject difference hypothesis http://purl.obolibrary.org/obo/STATO_0000065 hypothesis is a null hypothesis stating that there are no difference observed across a series of measurements made one same subject.
http://purl.obolibrary.org/obo/STATO_0000063 genomic coordinate datum http://purl.obolibrary.org/obo/IAO_0000027 data item genomic coordinate datum is a data item which denotes a genomic position expressed using a genomic coordinate system
http://purl.obolibrary.org/obo/STATO_0000065 hypothesis http://purl.obolibrary.org/obo/IAO_0000030 information content entity In statistics, a statement that can be tested.[wolfram alpha]
http://purl.obolibrary.org/obo/STATO_0000067 continuous probability distribution http://purl.obolibrary.org/obo/STATO_0000225 probability distribution a continuousprobability distribution is a probability distribution which is defined by a probability density function
http://purl.obolibrary.org/obo/STATO_0000068 skewness http://purl.obolibrary.org/obo/IAO_0000027 data item Skewness is a data item indicating of the degree of asymmetry of a distribution.
http://purl.obolibrary.org/obo/STATO_0000070 Yate's corrected Chi-Squared test http://purl.obolibrary.org/obo/STATO_0000081 Pearson's Chi square test of independence between categorical variables Yate's corrected Chi-Squared test is a statistical test which is used to test the association/linkage/independence of 2 dichotomous variables while introducing a correction for using the continous Chi-squared distribution for the test.
To reduce the error in approximation, Frank Yates, an English statistician, suggested a correction for continuity that adjusts the formula for Pearson's chi-squared test by subtracting 0.5 from the difference between each observed value and its expected value in a 2 × 2 contingency table. This reduces the chi-squared value obtained and thus increases its p-value.
http://purl.obolibrary.org/obo/STATO_0000072 substrate concentration http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum substrate concentration is a scalar measurement datum which denotes the amount of molecular entity involved in an enzymatic reaction (or catalytic chemical reaction) and whose role in that reaction is as substrate.
http://purl.obolibrary.org/obo/STATO_0000073 Fisher's exact test http://purl.obolibrary.org/obo/STATO_0000027 test of association between categorical variables Fisher's exact test is a statistical test used to determine if there are nonrandom associations between two categorical variables.
http://purl.obolibrary.org/obo/STATO_0000074 Cochran-Mantel-Haenzel test for repeated tests of independence http://purl.obolibrary.org/obo/STATO_0000027 test of association between categorical variables Cochran-Mantel-Haenzel test for repeated tests of independence is a statitiscal test which allows the comparison of two groups on a dichotomous/categorical response. It is used when the effect of the explanatory variable on the response variable is influenced by covariates that can be controlled. It is often used in observational studies where random assignment of subjects to different treatments cannot be controlled, but influencing covariates can.
The null hypothesis is that the two nominal variables that are tested within each repetition are independent of each other. So there are 3 variables to consider: two categorical variables to be tested for independence of each other, and the third variable identifies the repeats.
http://purl.obolibrary.org/obo/STATO_0000078 Levene's test http://purl.obolibrary.org/obo/STATO_0000191 goodness of fit statistical test Levene's test is a null hypothesis statistical test which evaluates the null hypothesis of equality of variance in several populations.
http://purl.obolibrary.org/obo/STATO_0000079 Barlett's test http://purl.obolibrary.org/obo/STATO_0000191 goodness of fit statistical test Bartlett's test (see Snedecor and Cochran, 1989) is used to test if k samples are from populations with equal variances. Equal variances across samples is called homoscedasticity or homogeneity of variances. Some statistical tests, for example the analysis of variance, assume that variances are equal across groups or samples. The Bartlett test can be used to verify that assumption.
Bartlett's test is sensitive to departures from normality. That is, if the samples come from non-normal distributions, then Bartlett's test may simply be testing for non-normality. Levene's test and the Brown–Forsythe test are alternatives to the Bartlett test that are less sensitive to departures from normality.
http://purl.obolibrary.org/obo/STATO_0000080 Brown Forsythe test http://purl.obolibrary.org/obo/STATO_0000137 homoskedasticity test the Brown Forsythe test is a statistical test which evaluates if the variance of different groups are equal. It relies on computing the median rather than the mean, as used in the Levene's test for homoschedacity.
This test maybe used to, for instance, ensure that the conditions of applications of ANOVA are met.
http://purl.obolibrary.org/obo/STATO_0000082 fixed effects model http://purl.obolibrary.org/obo/STATO_0000107 statistical model a fixed effect model is a statistical model which represents the observed quantities in terms of explanatory variables that are treated as if the quantities were non-random.
http://purl.obolibrary.org/obo/STATO_0000084 multinomial probit regression for analysis of polychotomous dependent variable http://purl.obolibrary.org/obo/OBI_0200102 regression analysis method multinomial logistic regression model is a model which attempts to explain data distribution associated with *polychotomous* response/dependent variable in terms of values assumed by the independent variable uses a function of predictor/independent variable(s): the function used in this instance of regression modeling is probit function.
http://purl.obolibrary.org/obo/STATO_0000085 effect size estimate http://purl.obolibrary.org/obo/IAO_0000109 measurement data item effect size estimate is a data item about the direction and strength of the consequences of a causative agent as explored by statistical methods. Those methods produce estimates of the effect size, e.g. confidence interval
http://purl.obolibrary.org/obo/STATO_0000086 F-test http://purl.obolibrary.org/obo/STATO_0000191 goodness of fit statistical test an F-test is a statistical test which evaluates that the computed test statistics follows an F-distribution under the null hypothesis. The F-test is sensitive to departure from normality. F-test arise when decomposing the variability in a data set in terms of sum of squares.
http://purl.obolibrary.org/obo/STATO_0000088 study group population size http://purl.obolibrary.org/obo/STATO_0000047 count statistical sample size is a count evaluating the number of individual experimental units
http://purl.obolibrary.org/obo/STATO_0000089 case-control study design http://purl.obolibrary.org/obo/OBI_0500006 parallel group design a case-control study design is a observation study design which assess the risk of particular outcome (a trait or a disease) associated with an event (either an exposure or endogenous factor). A case-control study design therefore declares an exposure variable which is dichotomous in nature (exposed/non-exposed) and an outcome variable, which is also dichotomous (case or control), thus giving the name to the design. During the execution of the design, a case control study defines a population and counts the events to determine their frequency.
http://purl.obolibrary.org/obo/STATO_0000091 genome-wide association study http://purl.obolibrary.org/obo/STATO_0000235 genetic association study Genome wide association study is a kind of study whose objective is to detect association between genetic markers (SNP or otherwise) accross the genome and a trait which may be a disease or another phenotype (e.g. trait of agronomic relevance in animal or plant studies). Genome wide association study compare the allele frequencies in 2 populations, one free of the trait used as control, the other one showing the trait use as 'case'. GWAS studies implement case-control design
http://purl.obolibrary.org/obo/STATO_0000092 Wilcoxon signed rank test http://purl.obolibrary.org/obo/STATO_0000202 within subject comparison statistical test The Wilcoxon signed rank test is a statistical test which tests the null hypothesis that the median difference between pairs of observations is zero. This is the non-parametric analogue to the paired t-test, and should be used if the distribution of differences between pairs may be non-normally distributed.
The procedure involves a ranking, hence the name. The absolute value of the differences between observations are ranked from smallest to largest, with the smallest difference getting a rank of 1, then next larger difference getting a rank of 2, etc. Ties are given average ranks. The ranks of all differences in one direction are summed, and the ranks of all differences in the other direction are summed. The smaller of these two sums is the test statistic, W (sometimes symbolized Ts). Unlike most test statistics, smaller values of W are less likely under the null hypothesis.
http://purl.obolibrary.org/obo/STATO_0000093 date http://purl.obolibrary.org/obo/IAO_0000582 time stamped measurement datum
http://purl.obolibrary.org/obo/STATO_0000095 paired t-test http://purl.obolibrary.org/obo/STATO_0000202 within subject comparison statistical test paired t-test is a statistical test which is specifically designed to analysis differences between paired observations in the case of studies realizing repeated measures design with only 2 repeated measurements per subject (before and after treatment for example)
http://purl.obolibrary.org/obo/STATO_0000096 population stratification prior to sampling http://purl.obolibrary.org/obo/OBI_0000094 material processing stratification is a planned process which executes a stratification rule using as input a population and assign it member to mutually exclusive subpopulation based on the values defined by the stratification rule
http://purl.obolibrary.org/obo/STATO_0000097 statistical test power analysis http://purl.obolibrary.org/obo/OBI_0200000 data transformation stastical test power analysis is a data transformation which aims to determine the size of a statistical sample required to reach a desired significance level given a particular statistical test
http://purl.obolibrary.org/obo/STATO_0000098 two sample Hotelling T2 test http://purl.obolibrary.org/obo/STATO_0000279 between group comparison statistical test Hotelling's T2 test is a statistical test which is a generalization of Student's T-test to a assess if the means of a set of variables remains unchanged when studying 2 populations. It is a type of multivariate analysis
http://purl.obolibrary.org/obo/STATO_0000104 z-score http://purl.obolibrary.org/obo/IAO_0000109 measurement data item A z-score (also known as z-value, standard score, or normal score) is a measure of the divergence of an individual experimental result from the most probable result, the mean. Z is expressed in terms of the number of standard deviations from the mean value.
http://purl.obolibrary.org/obo/STATO_0000105 log signal intensity ratio http://purl.obolibrary.org/obo/IAO_0000109 measurement data item log signal intensity ratio is a data item which corresponding the logarithmitic base 2 of the ratio between 2 signal intensity, each corresponding to a condition.
http://purl.obolibrary.org/obo/STATO_0000106 probit regression for analysis of polychotomous dependent variable http://purl.obolibrary.org/obo/OBI_0200102 regression analysis method probit regression model is a model which attempts to explain data distribution associated with *dichotomous* response/dependent variable in terms of values assumed by the independent variable uses a function of predictor/independent variable(s): the function used in this instance of regression modeling is the probit function aka the quantile function, i.e., the inverse cumulative distribution function (CDF), associated with the standard normal distribution.
http://purl.obolibrary.org/obo/STATO_0000107 statistical model http://purl.obolibrary.org/obo/IAO_0000030 information content entity a statistical model is an information content entity which is a formalization of relationships between variables in the form of mathematical equations. A statistical model describes how one or more random variables are related to one or more other variables. The model is statistical as the variables are not deterministically but stochastically related.
http://purl.obolibrary.org/obo/STATO_0000108 linear regression for analysis of continuous dependent variable http://purl.obolibrary.org/obo/OBI_0200102 regression analysis method linear regression model is a model which attempts to explain data distribution associated with response/dependent variable in terms of values assumed by the independent variable uses a linear function or linear combination of the regression parameters and the predictor/independent variable(s).
linear regression modeling makes a number of assumptions, which includes homoskedasticity (constance of variance)
http://purl.obolibrary.org/obo/STATO_0000109 multinomial logistic regression for analysis of dichotomous dependent variable http://purl.obolibrary.org/obo/OBI_0200102 regression analysis method multinomial logistic regression model is a model which attempts to explain data distribution associated with *polychotomous* response/dependent variable in terms of values assumed by the independent variable uses a function of predictor/independent variable(s): the function used in this instance of regression modeling is logistic function.
http://purl.obolibrary.org/obo/STATO_0000111 sequence read http://purl.obolibrary.org/obo/OBI_0001573 DNA sequence data a sequence read is a DNA sequence data which is generated by a DNA sequencer
http://purl.obolibrary.org/obo/STATO_0000116 assess statistical evidence http://purl.obolibrary.org/obo/OBI_0000011 planned process the process of using statistical analysis for interpreting and communicating "what the data say".
http://purl.obolibrary.org/obo/STATO_0000117 discrete probability distribution http://purl.obolibrary.org/obo/STATO_0000225 probability distribution a discrete probability distribution is a probability distribution which is defined by a probability mass function where the random variable can only assume a finite number of values or infinitely countable values
http://purl.obolibrary.org/obo/STATO_0000118 ranking http://purl.obolibrary.org/obo/OBI_0200000 data transformation ranking is a data transformation which turns a non-ordinal variable into a Ordinal variable by sorting the values of the input variable and replacing their value by their position in the sorting result
http://purl.obolibrary.org/obo/STATO_0000119 model parameter estimation http://purl.obolibrary.org/obo/OBI_0200000 data transformation model parameter estimation is a data transformation that finds parameter values (the model parameter estimates) most compatible with the data as judged by the model.
http://purl.obolibrary.org/obo/STATO_0000121 association between categorical variables testing objective http://purl.obolibrary.org/obo/OBI_0000675 statistical hypothesis test objective the objective of a data transformation to evaluate a null hypothesis of absence of linkage between variables.
http://purl.obolibrary.org/obo/STATO_0000123 r2 http://purl.obolibrary.org/obo/STATO_0000142 correlation coefficient r2 is a correlation coefficient which is computed over the frequency of 2 dichotomous variable and is used as a measure of Linkage Disequilibrium and as input data item to the creation of an LD plot
http://purl.obolibrary.org/obo/STATO_0000124 stratification rule http://purl.obolibrary.org/obo/IAO_0000055 rule a stratification rule/criteria is a criteria used to determine population strata so that a stratification process implementing the rule can result in any member of the total population being assigned to one and only one stratum
http://purl.obolibrary.org/obo/STATO_0000130 Breslow-Day test for homogeneity of odds ratio http://purl.obolibrary.org/obo/STATO_0000247 odds ratio homogeneity test the Breslow-Day test is a statistical test which evaluates if the odds ratios are homogenous across N 2x2 contingency tables, for instance several 2x2 contingency tables associated with different strata of a stratified population when evaluating the relationship between exposure and outcome or associated with the different samples coming from several centres in a multicentric study in clinical trial context.
http://purl.obolibrary.org/obo/STATO_0000131 sphericity test http://purl.obolibrary.org/obo/OBI_0000673 statistical hypothesis test a sphericity test is a null hypothesis statistical testing procedure which posits a null hypothesis of equality of the variances of the differences between levels of the repeated measures factor
http://purl.obolibrary.org/obo/STATO_0000135 strictly standardized mean difference http://purl.obolibrary.org/obo/STATO_0000100 standardized mean difference strictly standardized mean difference (SSMS) is a standardized mean difference which corresponds to the ratio of mean to the standard deviation of the difference between two groups.
SSMD directly measures the magnitude of difference between two groups.
SSMD is widely used in High Content Screen for hit selection and quality control.
When the data is preprocessed using log-transformation as normally done in HTS experiments, SSMD is the mean of log fold change divided by the standard deviation of log fold change with respect to a negative reference.
In other words, SSMD is the average fold change (on the log scale) penalized by the variability of fold change (on the log scale).
For quality control, one index for the quality of an HTS assay is the magnitude of difference between a positive control and a negative reference in an assay plate. For hit selection, the size of effects of a compound (i.e., a small molecule or an siRNA) is represented by the magnitude of difference between the compound and a negative reference. SSMD directly measures the magnitude of difference between two groups. Therefore, SSMD can be used for both quality control and hit selection in HTS experiments.
http://purl.obolibrary.org/obo/STATO_0000136 Tarone's test for homogeneity of odds ratio http://purl.obolibrary.org/obo/STATO_0000247 odds ratio homogeneity test Tarone's test for homogeneity of odds ratio is a statistical test which evaluates the null hypothesis that odds ratio are homogeneous
http://purl.obolibrary.org/obo/STATO_0000137 homoskedasticity test http://purl.obolibrary.org/obo/OBI_0000673 statistical hypothesis test an homoskedasticity test is a statistical test aiming at evaluate if the variances from several random samples are similar
http://purl.obolibrary.org/obo/STATO_0000138 2 by 2 contingency table http://purl.obolibrary.org/obo/STATO_0000140 contingency table a 2x2 contingency table is a contingency table build for 2 dichotomous variables (i.e. 2 categorical variables, each with only 2 possible outcomes). It is the simplest of contingency tables
http://purl.obolibrary.org/obo/STATO_0000139 subject pairing http://purl.obolibrary.org/obo/OBI_0600015 group assignment a subject pairing is a planned process which executes a pairing rule and results in the creation of sets of 2 subjects meeting the pairing criteria
http://purl.obolibrary.org/obo/STATO_0000140 contingency table http://purl.obolibrary.org/obo/IAO_0000030 information content entity a contigency table is a data item which displays the (multivariate) frequency distribution of the possible values of categorical variables.
The first row of the table corresponds to categories of one categorical variable, the first column of the table corresponds to categories of the other categorical variable, the cells corresponding to each combination of categories is filled with the observed occurences in the sample being considered.
The table also contains marginal total (marginal sums) and grand total of the occurences
The term contingency table was first used by Karl Pearson in "On the Theory of Contingency and Its Relation to Association and Normal Correlation", part of the Drapers' Company Research Memoirs Biometric Series I published in 1904.
http://purl.obolibrary.org/obo/STATO_0000141 acute toxicity study http://purl.obolibrary.org/obo/OBI_0000066 investigation acute toxicity study is an investigation which use interventions organized according to a factorial design and a parallel group design to observe the effect of use of high dose xenobiotics in animal models or cellular models
http://purl.obolibrary.org/obo/STATO_0000142 correlation coefficient http://purl.obolibrary.org/obo/STATO_0000085 effect size estimate The correlation coefficient of two variables in a data sample is their covariance divided by the product of their individual standard deviations. It is a normalized measurement of how the two are linearly related.
http://purl.obolibrary.org/obo/STATO_0000143 Bayesian model selection http://purl.obolibrary.org/obo/STATO_0000328 statistical model selection a Bayesian model selection is a data transformation which is based on Bayesian statistics to compute Bayes factor in order to evaluate which model best explains data.
http://purl.obolibrary.org/obo/STATO_0000144 model parameter estimate http://purl.obolibrary.org/obo/IAO_0000027 data item a model parameter estimate is a data item which results from a model parameter estimation process and which provides a numerical value about a model parameter.
http://purl.obolibrary.org/obo/STATO_0000146 presence of between group difference hypothesis http://purl.obolibrary.org/obo/STATO_0000065 hypothesis a null hypothesis stating that there are differences observed between group of subjects
http://purl.obolibrary.org/obo/STATO_0000149 binomial logistic regression for analysis of dichotomous dependent variable http://purl.obolibrary.org/obo/OBI_0200102 regression analysis method binomial logistic regression model is a model which attempts to explain data distribution associated with *dichotomous* response/dependent variable in terms of values assumed by the independent variable uses a function of predictor/independent variable(s): the function used in this instance of regression modeling is logistic function.
http://purl.obolibrary.org/obo/STATO_0000150 minimum value http://purl.obolibrary.org/obo/IAO_0000109 measurement data item a minimum value is a data item which denotes the smallest value found in a dataset or resulting from a calculation.
http://purl.obolibrary.org/obo/STATO_0000151 maximum value http://purl.obolibrary.org/obo/IAO_0000109 measurement data item maximum value is a data item which denotes the largest value found in a dataset or resulting from a calculation.
http://purl.obolibrary.org/obo/STATO_0000152 quartile http://purl.obolibrary.org/obo/STATO_0000291 quantile a quartile is a quantile which splits data into sections accrued of 25% of data, so the first quartile delineates 25% of the data, the second quartile delineates 50% of the data and the third quartile, 75 % of the data
http://purl.obolibrary.org/obo/STATO_0000153 one sample Hotelling T2 test http://purl.obolibrary.org/obo/STATO_0000191 goodness of fit statistical test Hotelling's T2 test is a statistical test which is a generalization of Student's T-test to a assess if the means of a set of variables remains unchanged when studying 2 populations. It is a type of multivariate analysis
http://purl.obolibrary.org/obo/STATO_0000155 meta analysis http://purl.obolibrary.org/obo/OBI_0200000 data transformation meta-analysis is a data transformation which uses the effect size estimates from several independent quantitative scientific studies addressing the same question in order to assess finding consistency.
http://purl.obolibrary.org/obo/STATO_0000156 Scheffe test http://purl.obolibrary.org/obo/STATO_0000133 post-hoc analysis the Scheffe test is a data transformation which evaluates all possible contrasts and adjusting the levels significance by accounting for multiple comparison. The test is therefore conservative. Confidence intervals can be constructed for the corresponding linear regression. It was developped by American statistician Henry Scheffe in 1959.
http://purl.obolibrary.org/obo/STATO_0000157 Least significance different test http://purl.obolibrary.org/obo/STATO_0000133 post-hoc analysis the LSD test is a statistical test for multiple comparisons of treatments by means of least significant difference following an ANOVA analysis
http://purl.obolibrary.org/obo/STATO_0000158 presence of association hypothesis http://purl.obolibrary.org/obo/STATO_0000065 hypothesis a null hypothesis which states that a linkage exists between 2 categorical variables
http://purl.obolibrary.org/obo/STATO_0000160 exponential distribution http://purl.obolibrary.org/obo/STATO_0000067 continuous probability distribution The exponential distribution (a.k.a. negative exponential distribution) is the probability distribution that describes the time between events in a Poisson process, i.e. a process in which events occur continuously and independently at a constant average rate. It is the continuous analogue of the geometric distribution, and it has the key property of being memoryless.
http://purl.obolibrary.org/obo/STATO_0000161 data distribution http://purl.obolibrary.org/obo/IAO_0000030 information content entity variable distribution is data item which denotes the spatial resolution of data point making up a variable. variable distribution may be compared to a known probability distribution using goodness of fit test or plotting a quantile-quantile plot for visual assessment of the fit.
http://purl.obolibrary.org/obo/STATO_0000162 experimental unit role http://purl.obolibrary.org/obo/BFO_0000023 role the role played by an entity part of study group as defined by an experimental design and realized in a data analysis and data interpretation
http://purl.obolibrary.org/obo/STATO_0000163 trimmed mean http://purl.obolibrary.org/obo/STATO_0000029 measure of central tendency trimmed mean or truncated mean is a measure of central tendency which involves the calculation of the mean after discarding given parts of a probability distribution or sample at the high and low end, and typically discarding an equal amount of both
http://purl.obolibrary.org/obo/STATO_0000164 inter quartile range http://purl.obolibrary.org/obo/STATO_0000028 measure of variation The interquartile range is a data item which corresponds to the difference between the upper quartile (3rd quartile) and lower quartile (1st quartile).
The interquartile range contains the second quartile or median.
The interquartile range is a data item providing a measure of data dispersion
http://purl.obolibrary.org/obo/STATO_0000167 first quartile http://purl.obolibrary.org/obo/STATO_0000152 quartile the first quartile is a quartile which splits the lower 25 % of the data
http://purl.obolibrary.org/obo/STATO_0000170 third quartile http://purl.obolibrary.org/obo/STATO_0000152 quartile the first quartile is a quartile which splits the 75 % of the data
http://purl.obolibrary.org/obo/STATO_0000173 homogeneity test objective http://purl.obolibrary.org/obo/OBI_0000675 statistical hypothesis test objective homogeneity testing objective is the objective of a data transformation to test a null hypothesis that two or more sub-groups of a population share the same distribution of a single categorical variable.
For example, do people of different countries have the same proportion of smokers to non-smokers
http://purl.obolibrary.org/obo/STATO_0000175 confidence interval calculation http://purl.obolibrary.org/obo/OBI_0200000 data transformation confidence interval calculation is a data transformation which determines a confidence interval for a given statistical parameter
http://purl.obolibrary.org/obo/STATO_0000176 t-statistic http://purl.obolibrary.org/obo/STATO_0000039 statistic t-statistic is a statistic computed from observations and used to produce a p-value in statistical test when compared to a Student's t distribution.
http://purl.obolibrary.org/obo/STATO_0000178 kurtosis http://purl.obolibrary.org/obo/IAO_0000027 data item Kurtosis is a data item which denotes the degree of peakedness of a distribution. It is defined as a normalized form of the fourth central moment of a distribution.
http://purl.obolibrary.org/obo/STATO_0000179 ANCOVA http://purl.obolibrary.org/obo/OBI_0200000 data transformation ANCOVA or analysis of covariance is a data transformation which evaluates if population means of a dependent variable are equal across levels of a categorical independent variables while controlling for the effects of other continuous variable s, known as covariates. Therefore, when performing ANCOVA, we are adjusting the dependent variable means to what they would be if all groups were equal on the covariates.
It augments the ANOVA model with one or more additional quantitative variables, called covariates, which are related to the response variable. The covariates are included to reduce the variance in the error terms and provide more precise measurement of the treatment effects. ANCOVA is used to test the main and interaction effects of the factors, while controlling for the effects of the covariate
http://purl.obolibrary.org/obo/STATO_0000181 Hardy-Weinberg equilibrium testing http://purl.obolibrary.org/obo/STATO_0000191 goodness of fit statistical test Hardy-Weinberg equilibrium test is a statistical test which aims to evaluate if a population's proportion of allele is stable or not. It is used as means of quality control to evaluate possibility of genotyping error or population structure.
http://purl.obolibrary.org/obo/STATO_0000183 sphericity testing objective http://purl.obolibrary.org/obo/OBI_0000675 statistical hypothesis test objective sphericity testing objective is a statistical objective of a data transformation which aims to test a null hypothesis of sphericity holds.
http://purl.obolibrary.org/obo/STATO_0000185 2 by n contingency table http://purl.obolibrary.org/obo/STATO_0000140 contingency table a 2 by n contingency table is a contingency table built for one dichotomous variable (a categorical variable with only 2 outcomes) and one polychotomous variable (a polychomotomous variable with at least 2 outcomes)
http://purl.obolibrary.org/obo/STATO_0000187 Tukey HSD for Post-Hoc Analysis http://purl.obolibrary.org/obo/STATO_0000133 post-hoc analysis Tukey Honestly Significant Difference (HSD) test is a statistical test used following an ANOVA test yielding a statistically significant p-value in order to determine which means are different, to a given level of significance. The Tukey HSD test relies on the q-distribution.
The procedure is conservative, meaning that if sample sizes (the sizes of different study groups) are equal, the risk of a Type I error is exactly α, and if sample sizes are unequal it’s less than α.
http://purl.obolibrary.org/obo/STATO_0000188 average log signal intensity http://purl.obolibrary.org/obo/OBI_0000451 normalized data set average log signal intensity is a data time which corresponds to the sum of 2 distinct logarithm base 2 transformed signal intensity, each corresponding to a distinct condition of signal acquisition, divided by 2.
http://purl.obolibrary.org/obo/STATO_0000189 mixed model http://purl.obolibrary.org/obo/STATO_0000107 statistical model A mixed model is a statistical model containing both fixed effects and random effects
http://purl.obolibrary.org/obo/STATO_0000191 goodness of fit statistical test http://purl.obolibrary.org/obo/OBI_0000673 statistical hypothesis test a goodness of fit statistical test is a statistical test which aim to evaluate if a sample distribution can be considered equivalent to a theoretical distribution used as input
http://purl.obolibrary.org/obo/STATO_0000192 cartesian product http://purl.obolibrary.org/obo/OBI_0200000 data transformation a cartesian product is a data transformation which operates on a n Sets to produce a set of all possible ordered n-tuples where each element of the tuple comes from a Set
http://purl.obolibrary.org/obo/STATO_0000193 study group population http://purl.obolibrary.org/obo/OBI_0000181 population is a population whose individual members realize (may be expressed as) a combination of inclusion rule values specifications or resulting from a sampling process (e.g. recruitment followed by randomization to group) on which a number of measurements will be carried out, which may be used as input to statistical tests and statistical inference.
http://purl.obolibrary.org/obo/STATO_0000194 cartesian product 2 sets http://purl.obolibrary.org/obo/STATO_0000192 cartesian product self explanatory
http://purl.obolibrary.org/obo/STATO_0000195 number of factor level combinations http://purl.obolibrary.org/obo/IAO_0000109 measurement data item A non-negative integer defining how many combination of factor levels (or treatments in the statistical sense) are to be used in a study.
http://purl.obolibrary.org/obo/STATO_0000196 confidence interval http://purl.obolibrary.org/obo/IAO_0000027 data item A confidence interval is a data item which defines an range of values in which a measurement or trial falls corresponding to a given probability.
http://purl.obolibrary.org/obo/STATO_0000198 non-parametric test http://purl.obolibrary.org/obo/STATO_0000279 between group comparison statistical test a statistical test which makes no assumption about the underlying data distribution
http://purl.obolibrary.org/obo/STATO_0000199 Mauchly's test for sphericity http://purl.obolibrary.org/obo/STATO_0000131 sphericity test the Mauchly's test for sphericity is a statistical test which evaluates if the variance of the differences between all combinations of the groups are equal, a property known as 'sphericity' in the context of repeated measures. It is used for instance prior to repeated measure ANOVA.
The test works by assessing if a Wishart-distributed covariance matrix (or transformation thereof) is proportional to a given matrix.
http://purl.obolibrary.org/obo/STATO_0000200 statistical test power http://purl.obolibrary.org/obo/IAO_0000027 data item the statistical test power is data item which is about a statistical test and is obtained by subtracting the false negative rate (type II error rate) to 1.
The power of a statistical test is the probability that it will correctly lead to the rejection of a false null hypothesis (Greene 2000). The statistical power is the ability of a test to detect an effect, if the effect actually exists (High 2000).
http://purl.obolibrary.org/obo/STATO_0000202 within subject comparison statistical test http://purl.obolibrary.org/obo/OBI_0000673 statistical hypothesis test within subject comparison statistical test is a kind of statistical test which evaluates if a change occurs within one experimental unit over time following a treatment or an event
http://purl.obolibrary.org/obo/STATO_0000203 cohort http://purl.obolibrary.org/obo/STATO_0000193 study group population a cohort is a study group population where the members are human beings which meet inclusion criteria and undergo a longitudinal design
http://purl.obolibrary.org/obo/STATO_0000207 specifying null and alternate hypothesis http://purl.obolibrary.org/obo/OBI_0000011 planned process a planned process which etablishes and states the different hypothesis to be evaluated during a null hypothesis statistical test
http://purl.obolibrary.org/obo/STATO_0000208 alternative hypothesis http://purl.obolibrary.org/obo/STATO_0000065 hypothesis An alternative hypothesis is an hypothesis defined in a statistical test that is the opposite of the null hypothesis.
http://purl.obolibrary.org/obo/STATO_0000211 odds ratio homogeneity hypothesis http://purl.obolibrary.org/obo/STATO_0000065 hypothesis odds ratio homogeneity hypothesis is a null hypothesis stating that all odds ratio are homogenous, that is remain within the same range
http://purl.obolibrary.org/obo/STATO_0000212 tetrachoric correlation coefficient http://purl.obolibrary.org/obo/STATO_0000269 polychoric correlation coefficient a tetrachoric correlation coefficient is a polychoric correlation coefficient for 2 dichotomous variables used as proxy for correlation between 2 continuous latent variables.
http://purl.obolibrary.org/obo/STATO_0000213 continuous variable discretization http://purl.obolibrary.org/obo/OBI_0200000 data transformation discretization as a processing converting a continuous variable into a polychotomous variable by concretizing a set of discretization rules
http://purl.obolibrary.org/obo/STATO_0000215 ordered probit regression for analysis of ordinal dependent variable http://purl.obolibrary.org/obo/OBI_0200102 regression analysis method probit regression model is a model which attempts to explain data distribution associated with *ordinal* response/dependent variable in terms of values assumed by the independent variable uses a function of predictor/independent variable(s): the function used in this instance of regression modeling is the ordered probit function.
http://purl.obolibrary.org/obo/STATO_0000216 stratum population http://purl.obolibrary.org/obo/OBI_0000181 population a stratum population is a population resulting from a population stratification prior to sampling process which aims to produce homogenous subpopulations from an heterogeneous population by applying one or more stratification criteria
http://purl.obolibrary.org/obo/STATO_0000217 sphericity hypothesis http://purl.obolibrary.org/obo/STATO_0000065 hypothesis a null hypothesis which states that a given matrix is proportional to a Wishart-distributed covariance matrix
http://purl.obolibrary.org/obo/STATO_0000218 model fitting http://purl.obolibrary.org/obo/OBI_0200000 data transformation Model fitting is a data transformation process which evaluates if a model appropriately represents a dataset. A model fitting process tests the goodness of fit of the model to the data
http://purl.obolibrary.org/obo/STATO_0000222 graeco-latin square design http://purl.obolibrary.org/obo/STATO_0000046 block design graeco-latin square design is_a study design which allows in its simpler form controlling 3 levels of nuisance variables (also known as blocking variables). The 3 nuisance factors are divided into a tabular grid with the property that each row and each column receive each treatment exactly once.
http://purl.obolibrary.org/obo/STATO_0000223 group assignment based on blocking variable specification http://purl.obolibrary.org/obo/OBI_0600015 group assignment group assignment based on blocking variable specification is a kind of group assignment process which takes into account the levels assumed by a blocking variable to allocate subjects or experimental units to a treatment group
http://purl.obolibrary.org/obo/STATO_0000224 goodness of fit testing objective http://purl.obolibrary.org/obo/OBI_0000675 statistical hypothesis test objective A testing objective to ensure that the sample used in a statistical test actually follows a normal distribution.
http://purl.obolibrary.org/obo/STATO_0000225 probability distribution http://purl.obolibrary.org/obo/IAO_0000030 information content entity A probability distribution is a information content entity that specifies the probability of the value of a random variable.
For a discrete random variable, a mathematical formula that gives the probability of each value of the variable.
For a continuous random variable, a curve described by a mathematical formula which specifies, by way of areas under the curve, the probability that the variable falls within a particular interval.
http://purl.obolibrary.org/obo/STATO_0000229 Chi-square probability distribution http://purl.obolibrary.org/obo/STATO_0000067 continuous probability distribution Chi-square probability distribution with k degrees of freedom is a theoretical probability distribution which corresponds to the distribution of a sum of the squares of k independent standard normal random variables.
http://purl.obolibrary.org/obo/STATO_0000234 residual http://purl.obolibrary.org/obo/IAO_0000027 data item a residual is a data item which is the output of an error estimate or model fitting process and which is an observable estimate of the unobservable error
http://purl.obolibrary.org/obo/STATO_0000235 genetic association study http://purl.obolibrary.org/obo/OBI_0000066 investigation A genetic association study is a kind of study whose objective is to detect associations between phenotypes, between a phenotype and a genetic polymorphism or between two genetic polymorphisms.
http://purl.obolibrary.org/obo/STATO_0000236 coefficient of variation http://purl.obolibrary.org/obo/STATO_0000028 measure of variation the coefficient of variation is a normalized measure fo dispersion of a probability distribution of frequency distribution.
http://purl.obolibrary.org/obo/STATO_0000239 high throughput screening http://purl.obolibrary.org/obo/OBI_0000066 investigation high throughput screening is a kind of investigation which uses a standardized assays (cell based, enzymatic or chemometric) to test the effect of substances (RNAi or small molecules) held in libraries on a very specific and measureable outcome (e.g fluorence intensity). it relies on robotic handling to ensure fast and high-throughput in assay performance, data acquisition and hit selection.
http://purl.obolibrary.org/obo/STATO_0000242 statistical error http://purl.obolibrary.org/obo/IAO_0000027 data item statistical error is an data item denoting the amount by which an observation differs from the expected value, being based on the whole statistical population from which the statistical unit was chosen randomly
http://purl.obolibrary.org/obo/STATO_0000244 ΔRn http://purl.obolibrary.org/obo/IAO_0000027 data item (Rn +) − (Rn −), where Rn + = (emission intensity of reporter dye)/(emission intensity of passive reference dye) in PCR with template and Rn − = (emission intensity of reporter dye)/(emission intensity of passive reference dye) in PCR without template or early cycles of a real-time reaction. Ct = threshold cycle, i.e., cycle at which a statistically significant increase in ΔRn is first detected
http://purl.obolibrary.org/obo/STATO_0000246 Woolf's test http://purl.obolibrary.org/obo/STATO_0000247 odds ratio homogeneity test Woolf's test is a statistical test which evaluates the null hypothesis that odds ratio are the same accross all strata of population under investigation
http://purl.obolibrary.org/obo/STATO_0000247 odds ratio homogeneity test http://purl.obolibrary.org/obo/OBI_0000673 statistical hypothesis test odds ratio homogeneity test is a statistical test which aims to evaluate that null the hypothesis of consistency odds ratio accross different strata of population is true or not
http://purl.obolibrary.org/obo/STATO_0000249 DNA microarray hybridization http://purl.obolibrary.org/obo/OBI_0000070 assay a DNA microarray hybridization is an assay relying on nucleic acid hybridization , which uses a DNA microarray device and a nucleic acid as input. It precedes a data acquisition process
http://purl.obolibrary.org/obo/STATO_0000250 group comparison objective http://purl.obolibrary.org/obo/OBI_0200166 data transformation objective group comparison objective is a data transformation objective which aims to determine if 2 or more study group differ with respect to the signal of a response variable
http://purl.obolibrary.org/obo/STATO_0000253 within subject comparison objective http://purl.obolibrary.org/obo/OBI_0000675 statistical hypothesis test objective the objective of a data transformation to test a null hypothesis of absence of difference within subject holds.
http://purl.obolibrary.org/obo/STATO_0000255 between group comparison objective http://purl.obolibrary.org/obo/OBI_0000675 statistical hypothesis test objective the objective of a data transformation to test a null hypothesis of absence of difference withing subject holds.
http://purl.obolibrary.org/obo/STATO_0000257 family http://purl.obolibrary.org/obo/OBI_0000181 population A domestic group, or a number of domestic groups linked through descent (demonstrated or stipulated) from a common ancestor, marriage, or adoption.
http://purl.obolibrary.org/obo/STATO_0000261 Newman-Keuls test post-hoc analysis http://purl.obolibrary.org/obo/STATO_0000133 post-hoc analysis The Newman–Keuls or Student–Newman–Keuls (SNK) method is a stepwise multiple comparisons procedure used to identify sample means that are significantly different from each other. It was named after Student (1927), D. Newman, and M. Keuls. This procedure is often used as a post-hoc test whenever a significant difference between three or more sample means has been revealed by an analysis of variance (ANOVA). The Newman–Keuls method is similar to Tukey's range test as both procedures use Studentized range statistics.Compared to Tukey's range test, the Newman–Keuls method is more powerful but less conservative.
http://purl.obolibrary.org/obo/STATO_0000266 Bayes factor http://purl.obolibrary.org/obo/IAO_0000109 measurement data item Bayes factor is a ratio between 2 probabilities of observing data according 2 distinct models. It is used in Bayes model selection to evaluate which model best explains the data. if K<0, the model used in the denominator term is supported, if K>1, the model used in the numerator term is supported.
The Bayes factor is about the plausibility of 2 different models
http://purl.obolibrary.org/obo/STATO_0000268 Gamma distribution http://purl.obolibrary.org/obo/STATO_0000067 continuous probability distribution A gamma distribution is a general type of continous statistical distribution (related to the beta distribution) that arises naturally in processes for which the waiting times between Poisson distributed events are relevant. Gamma distributions have two free parameters shape k and scale denoted theta .
http://purl.obolibrary.org/obo/STATO_0000269 polychoric correlation coefficient http://purl.obolibrary.org/obo/STATO_0000142 correlation coefficient polychoric correlation coefficient is a correlation coefficient which is computed over 2 variables to characterise an association by proxy with 2 (latent) variables which are assumed to be continuous and normally distributed.
http://purl.obolibrary.org/obo/STATO_0000270 full factorial design http://purl.obolibrary.org/obo/OBI_0500014 factorial design a full factorial design is a factorial design which ensures that all possible factor level combinations are defined and used so all between group differences can be explored
http://purl.obolibrary.org/obo/STATO_0000271 permutation numbering http://purl.obolibrary.org/obo/OBI_0200000 data transformation permutation numbering is a data tranformation allowing to count the number of possible permutations of elements in a set of size n, each element occurring exactly once. This number is factorial n.
http://purl.obolibrary.org/obo/STATO_0000272 Michaelis-Menten constant http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum The Michaelis constant is the substrate concentration at which the reaction rate is at half-maximum, and is an inverse measure of the substrate's affinity for the enzyme—as a small indicates high affinity, meaning that the rate will approach more quickly.[5] The value of is dependent on both the enzyme and the substrate, as well as conditions such as temperature and pH.
http://purl.obolibrary.org/obo/STATO_0000273 child-parents trio http://purl.obolibrary.org/obo/STATO_0000257 family A population of two parents and a child.
http://purl.obolibrary.org/obo/STATO_0000276 binomial distribution http://purl.obolibrary.org/obo/STATO_0000117 discrete probability distribution The binomial distribution is a discrete probability distribution which describes the probability of k successes in n draws with replacement from a finite population of size N.
The binomial distribution is frequently used to model the number of successes in a sample of size n drawn with replacement from a population of size N.
The binomial distribution gives the discrete probability distribution of obtaining exactly n successes out of N Bernoulli trials (where the result of each Bernoulli trial is true with probability p and false with probability q=1-p )
notation: B(n,p)
The mean is N*p
The variance is N*p*q
http://purl.obolibrary.org/obo/STATO_0000277 hit selection http://purl.obolibrary.org/obo/OBI_0000011 planned process hit selection is a planned process which in screening processes such as high-throughput screening, lead to the identification of perturbing agent which cause the typical signal generated by a standardized assay to significantly differ from the negative control. The selection hitself results from meeting or exceeding selection threshold (for instance 6 sigma from the mean or SSMD value beyond 5 when compared to positive controls or below -5 when compared to negative controls
http://purl.obolibrary.org/obo/STATO_0000278 pairing rule http://purl.obolibrary.org/obo/IAO_0000055 rule pairing rule is a rule which is specifies the criteria for deciding on how to associated any 2 entities.
http://purl.obolibrary.org/obo/STATO_0000279 between group comparison statistical test http://purl.obolibrary.org/obo/OBI_0000673 statistical hypothesis test between group comparison statistical test is a statistical test which aims to detect difference between the means computing for each of the study group populations
http://purl.obolibrary.org/obo/STATO_0000284 Breusch-Pagan test http://purl.obolibrary.org/obo/STATO_0000137 homoskedasticity test Breusch-Pagan test is a statistical test which computes a score test of the hypothesis of constant error variance against the alternative that the error variance changes with the level of the response (fitted values), or with a linear combination of predictors.
http://purl.obolibrary.org/obo/STATO_0000285 hypergeometric test http://purl.obolibrary.org/obo/STATO_0000287 two tailed test hypergeometric test is a null hypothesis test which evaluates if a random variable follows a hypergeometric distribution. It is a test of goodness of fit to that distribution. The test is suited for situation aimed at assessing cases of sampling from a finite set without replacements. For instance, testing for enrichment or depletion of elements (e.g GO categories, genes)
http://purl.obolibrary.org/obo/STATO_0000288 absence of difference hypothesis http://purl.obolibrary.org/obo/STATO_0000065 hypothesis A null hypothesis which states that no difference exists between 2 or more groups being considered.
http://purl.obolibrary.org/obo/STATO_0000290 contrast http://purl.obolibrary.org/obo/IAO_0000027 data item A contrast is the weighted sum of group means, the c_j coefficients represent the assigned weights of the means (these must sum to 0 for orthogonal contrasts)
http://purl.obolibrary.org/obo/STATO_0000291 quantile http://purl.obolibrary.org/obo/IAO_0000027 data item a quantile is a data item which corresponds to specific elements x in the range of a variate X.
the k-th n-tile P_k is that value of x, say x_k, which corresponds to a cumulative frequency of Nk/n (Kenney and Keeping 1962). If n=4, the quantity is called a quartile, and if n=100, it is called a percentile.
http://purl.obolibrary.org/obo/STATO_0000292 decile http://purl.obolibrary.org/obo/STATO_0000291 quantile a decile is a quantile where n=10 and which splits data into sections accrued of 10% of data, so the first decile delineates 10% of the data, the second decile delineates 20% of the data and the nineth decile, 90 % of the data
http://purl.obolibrary.org/obo/STATO_0000293 percentile http://purl.obolibrary.org/obo/STATO_0000291 quantile a percentile is a quantile which splits data into sections accrued of 1% of data, so the first percentile delineates 1% of the data, the second quartile delineates 2% of the data and the 99th percentile, 99 % of the data
http://purl.obolibrary.org/obo/STATO_0000294 absence of negative difference hypothesis http://purl.obolibrary.org/obo/STATO_0000065 hypothesis absence of negative difference hypothesis is a hypothesis which assumes that a difference significantly less than a threshold does not exist.
http://purl.obolibrary.org/obo/STATO_0000295 absence of positive difference hypothesis http://purl.obolibrary.org/obo/STATO_0000065 hypothesis absence of negative difference hypothesis is a hypothesis which assumes that a difference significantly greater than a threshold does not exist.
http://purl.obolibrary.org/obo/STATO_0000298 exact binomial test http://purl.obolibrary.org/obo/STATO_0000191 goodness of fit statistical test a binomial test is a statistical hypothesis test which evaluates if the observations made about a Bernoulli experiment , that is an experiment which tests the statistical significance of deviations from a theoretically expected distribution (the binomial distribution) of observations into 2 categories. It is a goodness of fit test.
http://purl.obolibrary.org/obo/STATO_0000299 statistical inference http://purl.obolibrary.org/obo/OBI_0001834 drawing a conclusion statistical inference is a process of drawing conclusions following data analysis using statistical methods (statistical tests) and evaluating whether to reject or accept null hypothesis
http://purl.obolibrary.org/obo/STATO_0000301 covariance http://purl.obolibrary.org/obo/IAO_0000109 measurement data item The covariance is a measurement data item about the strength of correlation between a set (2 or more) of random variables.
The covariance is obtained by forming:
cov(X,Y)=E([X-E(X)][Y-E(Y)] where E(X), E(Y) is the expected value (mean) of variable X and Y respectively.
covariance is symmetric so cov(X,Y)=cov(Y,X).
The covariance is usefull when looking at the variance of the sum of the 2 random variables since:
var(X+Y) = var(X) +var(Y) +2cov(X,Y)
The covariance cov(x,y) is used to obtain the coefficient of correlation cor(x,y) by normalizing (dividing) cov(x,y) but the product of the standard deviations of x and y.
http://purl.obolibrary.org/obo/STATO_0000302 one sample t-test http://purl.obolibrary.org/obo/STATO_0000279 between group comparison statistical test one sample t-test is a kind of Student's t-test which evaluates if a given sample can be reasonably assumed to be taken from the population.
The test compares the sample statistic (m) to the population parameter (M).
The one sample t-test is the small sample analog of the z test, which is suitable for large samples.
http://purl.obolibrary.org/obo/STATO_0000305 Helmert contrast http://purl.obolibrary.org/obo/STATO_0000290 contrast A Helmert contrast is a contrast in which the coefficients for the Helmert regressors compare each level with the average of the “preceding” ones
http://purl.obolibrary.org/obo/STATO_0000306 polynomial contrast http://purl.obolibrary.org/obo/STATO_0000290 contrast a polynomial contrast is a contrast which...
http://purl.obolibrary.org/obo/STATO_0000307 treatment contrast http://purl.obolibrary.org/obo/STATO_0000290 contrast treatment contrast is a contrast which allows to test how linear model coefficients of categorical variables are interpreted in case where the “first” level (aka, the baseline) is included into the intercept and all subsequent levels have a coefficient that represents their difference from the baseline.
http://purl.obolibrary.org/obo/STATO_0000308 sum contrast http://purl.obolibrary.org/obo/STATO_0000290 contrast the sum contrast is a contrast in which each coefficient compares the corresponding level of the factor to the average of the other levels
http://purl.obolibrary.org/obo/STATO_0000310 Barnard's test http://purl.obolibrary.org/obo/STATO_0000027 test of association between categorical variables Barnard's test is an exact statistical test used to determine if there are nonrandom associations between two categorical variables. It was developed in 1949 by Barnard and is a test which is, most times, more powerfull that the Fisher exact test
http://purl.obolibrary.org/obo/STATO_0000311 central composite design http://purl.obolibrary.org/obo/OBI_0500000 study design a central composite design is a study design which contains an imbedded factorial or fractional factorial design with center points that is augmented with a group of so-called 'star points' that allow estimation of curvature.
A CCD design with k factors has 2k star points.
http://purl.obolibrary.org/obo/STATO_0000312 Box–Behnkens design http://purl.obolibrary.org/obo/OBI_0500000 study design The Box-Behnken design is an independent quadratic design in that it does not contain an embedded factorial or fractional factorial design. In this design the treatment combinations are at the midpoints of edges of the process space and at the center. These designs are rotatable (or near rotatable) and require 3 levels of each factor. The designs have limited capability for orthogonal blocking compared to the central composite designs.
http://purl.obolibrary.org/obo/STATO_0000313 Plackett-Burman design http://purl.obolibrary.org/obo/OBI_0500000 study design Plackett-Burman design is a type of study design optimizing multifactorial experiments characterized by their parsimony and economy with the run number a multiple of 4 (rather than a power of 2).
Plackett-Burman design is often used for screening experiments where the main effect is often heavily confounded with two-factor interactions.
This type of design is very useful for economically detecting large main effects, assuming all interactions are negligible when compared with the few important main effects.
http://purl.obolibrary.org/obo/STATO_0000314 upper confidence limit http://purl.obolibrary.org/obo/IAO_0000027 data item upper confidence limit is a data item which is a largest value bounding a confidence interval
http://purl.obolibrary.org/obo/STATO_0000315 lower confidence limit http://purl.obolibrary.org/obo/IAO_0000027 data item lower confidence limit is a data item which is a lowest value bounding a confidence interval
http://purl.obolibrary.org/obo/STATO_0000317 eta-squared http://purl.obolibrary.org/obo/STATO_0000085 effect size estimate Eta-squared is a biased estimator of the variance explained by the model in the population (it estimates only the effect size in the sample). Eta-squared describes the ratio of variance explained in the dependent variable by a predictor while controlling for other predictors, making it analogous to the r2. This estimate shares the weakness with r2 that each additional variable will automatically increase the value of η2. In addition, it measures the variance explained of the sample, not the population, meaning that it will always overestimate the effect size, although the bias grows smaller as the sample grows larger.
http://purl.obolibrary.org/obo/STATO_0000318 omega-squared http://purl.obolibrary.org/obo/STATO_0000085 effect size estimate omega-squared is a effect size estimate for variance explained which is less biased than the eta-squared coefficient.
http://purl.obolibrary.org/obo/STATO_0000319 Hedges's g http://purl.obolibrary.org/obo/STATO_0000085 effect size estimate Hedges's g is an estimator of effect size, which is similar to Cohen's d and is a measure based on a standardized difference. However, the denominator, corresponding to a pooled standard deviation, is computed differently from Cohen's d coefficient, by applying a correction factor (which involves a Gamma function).
http://purl.obolibrary.org/obo/STATO_0000320 Glass's delta http://purl.obolibrary.org/obo/STATO_0000085 effect size estimate Glass's delta is an estimator of effect size which is similar to Cohen's d but where the denominator corresponds only to the standard deviation of the control group (or second group). It is considered less biais than the Cohen's d for estimating effect sizes based on means and distances between means.
http://purl.obolibrary.org/obo/STATO_0000321 non-parametric distribution http://purl.obolibrary.org/obo/STATO_0000329 symmetric distribution Probability distribution estimated empirically on the data without assumptions on the shape of the probability distribution.
http://purl.obolibrary.org/obo/STATO_0000322 contrast weight http://purl.obolibrary.org/obo/IAO_0000027 data item a contrast weight is a coefficient which multiplies a group mean, part of a linear combinaison defining a constrast as a weighted sum of group means, giving a 'weight' to a specific group mean hence the name.
http://purl.obolibrary.org/obo/STATO_0000323 contrast weight matrix http://purl.obolibrary.org/obo/IAO_0000030 information content entity a contrast weight matrix is a information content entity which holds a set of contrast weight, coefficient used in a weighting sum of means defining a contrast
http://purl.obolibrary.org/obo/STATO_0000324 contrast weight estimate http://purl.obolibrary.org/obo/STATO_0000144 model parameter estimate contrast weight estimate is a model parameter estimate which results from the computation from the data and that is used as input to a model fitting process
http://purl.obolibrary.org/obo/STATO_0000325 Akaike information criterion http://purl.obolibrary.org/obo/IAO_0000109 measurement data item The Akaike information criterion (AIC) is a measure of the relative quality of a statistical model for a given set of data. As such, AIC provides a means for model selection. AIC is defined as:
AIC = 2K - 2log(L)
where K is the number of predictors and L is the maximized likelihood value.
AIC deals with the trade-off between the goodness of fit of the model and the complexity of the model. It is founded on information theory: it offers a relative estimate of the information lost when a given model is used to represent the process that generates the data. AIC does not provide a test of a model in the sense of testing a null hypothesis; i.e. AIC can tell nothing about the quality of the model in an absolute sense. If all the candidate models fit poorly, AIC will not give any warning of that.
http://purl.obolibrary.org/obo/STATO_0000326 corrected Akaike information criterion http://purl.obolibrary.org/obo/STATO_0000325 Akaike information criterion corrected Akaike information criteria is a modified version of the Akaike information criterion
http://purl.obolibrary.org/obo/STATO_0000327 Bayesian information criterion http://purl.obolibrary.org/obo/IAO_0000109 measurement data item Bayesian information criterion or Schwartz's Bayesian information criterion is a criterion for model selection among a finite set of models. It is based, in part, on the likelihood function and it is closely related to the Akaike information criterion (AIC).
Given any two estimated models, the model with the lower value of BIC is the one to be preferred. The BIC is an increasing function of sigma_e^2 and an increasing function of k. That is, unexplained variation in the dependent variable and the number of explanatory variables increase the value of BIC. Hence, lower BIC implies either fewer explanatory variables, better fit, or both.
http://purl.obolibrary.org/obo/STATO_0000328 statistical model selection http://purl.obolibrary.org/obo/OBI_0200000 data transformation a statistical model selection is a data transformation which is based on computing a relative quality value in order to evaluate and select which model best explains data.
http://purl.obolibrary.org/obo/STATO_0000329 symmetric distribution http://purl.obolibrary.org/obo/STATO_0000225 probability distribution Probability distribution which has no skew so its skewness=0
http://purl.obolibrary.org/obo/STATO_0000330 empirical distribution http://purl.obolibrary.org/obo/STATO_0000225 probability distribution Probability distribution estimated empirically from all acquired data
http://purl.obolibrary.org/obo/STATO_0000331 histogram distribution http://purl.obolibrary.org/obo/STATO_0000225 probability distribution Probability distribution estimated empirically on the data following a binning process
http://purl.obolibrary.org/obo/STATO_0000332 smooth kernel distribution http://purl.obolibrary.org/obo/STATO_0000225 probability distribution Probability distribution estimated using a smooth kernel function to avoid making assumptions about the distribution of the data. The kernel density estimator is the estimated probability density function (pdf) of the random variable.
http://purl.obolibrary.org/obo/STATO_0000333 kernel mixture distribution http://purl.obolibrary.org/obo/STATO_0000225 probability distribution kernel density estimation (KDE) is a non-parametric way to estimate the probability density function of a random variable
http://purl.obolibrary.org/obo/STATO_0000334 mixture distribution http://purl.obolibrary.org/obo/STATO_0000225 probability distribution Mixture distribution is the probability distribution of a random variable that is derived from a collection of other random variables as follows: first, a random variable is selected by chance from the collection according to given probabilities of selection, and then the value of the selected random variable is realized.
http://purl.obolibrary.org/obo/STATO_0000335 survival distribution http://purl.obolibrary.org/obo/STATO_0000330 empirical distribution Probability distribution estimated empirically from a censored lifetime data
http://purl.obolibrary.org/obo/STATO_0000346 covariance structure http://purl.obolibrary.org/obo/IAO_0000027 data item a covariance structure is a data item which is part of a regression model and which indicates a pattern in the covariance matrix. The nature of covariance structure is specified before the regression analysis and various covariance structure may be tested and evaluated using information criteria to help choose the most suiteable model
http://purl.obolibrary.org/obo/STATO_0000368 Mallows' Cp http://purl.obolibrary.org/obo/IAO_0000109 measurement data item Mallows' Cp is a data item which compares the precision and bias of the full model to models with a subset of the predictors thus helping to choose between multiple regression models.
the mallows cp is a function of the number of parameter used in the model relying on the residuals sum of squares to compute a score.
the smaller Cp is, the better the model fit is.
http://purl.obolibrary.org/obo/STATO_0000369 repeated measure analysis http://purl.obolibrary.org/obo/OBI_0200000 data transformation repeated measure analysis is a kind of data transformation which deals with signals measured in the same experimental units at different times and, possibly, under different conditions over a period of time. Data produced by longitudinal studies qualify for such analysis. Since measurements are made on the same experimental units a number of times, they are likely to be correlated. Repeated measure analysis usually takes into consideration the possibility of correlation with time. It does so by specifying covariance structure in the analysis
http://purl.obolibrary.org/obo/STATO_0000370 ordinary least squares estimation http://purl.obolibrary.org/obo/STATO_0000119 model parameter estimation the ordinary least squares estimation is a model parameter estimation for a linear regression model when the errors are uncorrelated and equal in variance. Is the Best Linear Unbiased Estimation (BLUE) method under these assumptions, Uniformly Minimum-Variance Unbiased Estimator (UMVUE) with addition of a Gaussian assumption.
http://purl.obolibrary.org/obo/STATO_0000371 weighted least squares estimation http://purl.obolibrary.org/obo/STATO_0000119 model parameter estimation the weighted least squares estimation is a model parameter estimation for a linear regression model with errors that independent but have heterogeneous variance. Difficult to use use in practice, as weights must be set based on the variance which is usually unknown. If true variance is known, it is the Best Linear Unbiased Estimation (BLUE) method under these assumptions, Uniformly Minimum-Variance Unbiased Estimator (UMVUE) with addition of a Gaussian assumption.
http://purl.obolibrary.org/obo/STATO_0000372 generalized least squares estimation http://purl.obolibrary.org/obo/STATO_0000119 model parameter estimation the generalized least squares estimation is a model parameter estimation for a linear regression model with errors that are dependent and (possibly) have heterogeneous variance. Difficult to use use in practice, as covariance matrix of the errors must known to "whiten" data and model. If true covariance is known, it is the Best Linear Unbiased Estimation (BLUE) method under these assumptions, Uniformly Minimum-Variance Unbiased Estimator (UMVUE) with addition of a Gaussian assumption.
http://purl.obolibrary.org/obo/STATO_0000373 iteratively reweighted least squares estimation http://purl.obolibrary.org/obo/STATO_0000119 model parameter estimation the iteratively reweighted least squares estimation is a model parameter estimation which is a practical implementation of Weighted Least Squares, where the heterogeneous variances of the errors are estimated from the residuals of the regression model, providing an estimate for the weights. Each successive estimate of the weights improves the estimation of the regression parameters, which in turn are used to compute residuals and update the weights
http://purl.obolibrary.org/obo/STATO_0000374 feasible generalized least squares estimation http://purl.obolibrary.org/obo/STATO_0000372 generalized least squares estimation the feasible generalized least squares estimation is a model parameter estimation which is a practical implementation of Generalised Least Squares, where the covariance of the errors is estimated from the residuals of the regression model, providing the information needed to whiten the data and model. Each successive estimate of the whitening matrix improves the estimation of the regression parameters, which in turn are used to compute residuals and update the whitening matrix.
http://purl.obolibrary.org/obo/STATO_0000375 residual mean square http://purl.obolibrary.org/obo/IAO_0000027 data item a residual mean square is a data item which is obtained by dividing the sum of squared residuals (SSR) by the number of degrees of freedom
http://purl.obolibrary.org/obo/STATO_0000376 Z-statistic http://purl.obolibrary.org/obo/STATO_0000039 statistic Z-statistic is a statistic computed from observations and used to produce a p-value when compared to a Standard Normal Distribution in a statistical test called the Z-test.
http://purl.obolibrary.org/obo/STATO_0000377 deviance http://purl.obolibrary.org/obo/IAO_0000027 data item Deviance is an indicator of fit and can be estimated by computing -2 times the log-likelihood ratio of the fitted model compared to a saturated(full) model.
It is a generalization of the idea of using the sum of squares of residuals in ordinary least squares to cases where model-fitting is achieved by maximum likelihood.
http://purl.obolibrary.org/obo/STATO_0000378 deviance information criterion http://purl.obolibrary.org/obo/IAO_0000109 measurement data item The deviance information criterion (DIC) is a hierarchical modeling generalization of the AIC (Akaike information criterion) and BIC (Bayesian information criterion, also known as the Schwarz criterion). It is particularly useful in Bayesian model selection problems where the posterior distributions of the models have been obtained by Markov chain Monte Carlo (MCMC) simulation. Like AIC and BIC it is an asymptotic approximation as the sample size becomes large. It is only valid when the posterior distribution is approximately multivariate normal.
The deviance information criterion was published in 2002 by Spiegelhalter et al.
Spiegelhalter, D. J., N. G. Best, B. P. Carlin, and A. van der Linde, 2002. Bayesian measures of model complexity and fit. Journal of the Royal Statistical Society, B, 64, 583-639.
http://purl.obolibrary.org/obo/STATO_0000379 focused information criterion http://purl.obolibrary.org/obo/IAO_0000109 measurement data item The focused information criterion is a measurement data item which aims at facilitating model selection. It was published in 2003 by Claeskens, G. and Hjort, N.L. (2003). "The focused information criterion". Journal of the American Statistical Association, volume 98, pp. 879–899. doi:10.1198/016214503000000819
http://purl.obolibrary.org/obo/STATO_0000383 contrast estimation http://purl.obolibrary.org/obo/OBI_0200000 data transformation a data transformation that finds a contrast value (the contrast estimate) by computing the weighted sum of model parameter estimates using a set of contrast weights.
http://purl.obolibrary.org/obo/STATO_0000384 contrast estimate http://purl.obolibrary.org/obo/IAO_0000027 data item estimate of a contrast obtained by computing the weighted sum of model parameter estimates using a set of contrast weights.
http://purl.obolibrary.org/obo/STATO_0000385 standard error of a contrast estimate http://purl.obolibrary.org/obo/IAO_0000109 measurement data item an estimate of the standard deviation of a contrast estimate sampling distribution.
http://purl.obolibrary.org/obo/STATO_0000386 scree plot http://purl.obolibrary.org/obo/IAO_0000038 graph A scree plot is a graphical display of the variance of each component in the dataset which is used to determine how many components should be retained in order to explain a high percentage of the variation in the data
http://purl.obolibrary.org/obo/STATO_0000387 scatterplot matrix http://purl.obolibrary.org/obo/IAO_0000038 graph A scatterplot matrix contains all the pairwise scatter plots of a set of variables on a single page in a matrix format.
http://purl.obolibrary.org/obo/STATO_0000388 alpha distribution http://purl.obolibrary.org/obo/STATO_0000067 continuous probability distribution
http://purl.obolibrary.org/obo/STATO_0000389 power law distribution http://purl.obolibrary.org/obo/STATO_0000225 probability distribution a power-law probability distribution is a probability distribution whose density function (or mass function in the discrete case) has the form
p(x) = L(x) . x^{-alpha}
where alpha is a parameter >1 and L(x) is a slowly varying function.
http://purl.obolibrary.org/obo/STATO_0000390 regression model http://purl.obolibrary.org/obo/STATO_0000107 statistical model A regression model is a statistical model used in a type of analysis knowns as regression analysis, whereby a function is used to determine the relation between a response variable and an independent variable , with a set of unknown parameters.
http://purl.obolibrary.org/obo/STATO_0000392 Pareto type-I probability distribution http://purl.obolibrary.org/obo/STATO_0000067 continuous probability distribution The Pareto distribution is a continuous probability distribution, which is defined by the follwoing probability density (1) function and distribution function (2)
(1): P(x)=(ab^a)/(x^(a+1))
(2): D(x)=1-(b/x)^a
defined over the interval x>=b.
http://purl.obolibrary.org/obo/STATO_0000393 Pareto type-II probability distribution http://purl.obolibrary.org/obo/STATO_0000067 continuous probability distribution the Pareto type-II probability distribution is a continuous probability distribution which is defined by a probability density function characterized by 2 parameters, alpha and lambda, 2 real, strictly positive numbers. alpha is known as the shape parameter while lambda is known as the scale parameter.
the function defines the probably of a continous random variable according to the following:
p(x) = {\alpha \over \lambda} \left[{1+ {x \over \lambda}}\right]^{-(\alpha+1)}, \qquad x \geq 0,
http://purl.obolibrary.org/obo/STATO_0000394 Pareto type-III probability distribution http://purl.obolibrary.org/obo/STATO_0000067 continuous probability distribution The Pareto(III) distribution is a continous probability distribution which is described with a cumulative distribution function of the following form:
F(x) = 1 − [1 + ((x − mu)/sigma)1/gamma]−1
for x > mu, sigma > 0, gamma > 0 and s =1.
a is the location parameter,
b is the scale parameter,
g is the inequality parameter
s is the shape parameter of value 1
The Pareto III distribution corresponds to a Pareto Type IV distribution where the shape parameter has a value of 1.
http://purl.obolibrary.org/obo/STATO_0000395 Pareto type-IV probability distribution http://purl.obolibrary.org/obo/STATO_0000067 continuous probability distribution The Pareto(IV) distribution is a continous probability distribution which is described with a cumulative distribution function of the following form:
F(y) = 1 − [1 + ((y − a)/b)1/g]−s
for y > a, b > 0, g > 0 and s > 0.
a is the location parameter,
b is the scale parameter,
g is the inequality parameter
s is the shape parameter
The distribution is used in actuarial science, economics, finance and telecommunications, but not restricted to those fields.
http://purl.obolibrary.org/obo/STATO_0000396 geometric mean http://purl.obolibrary.org/obo/STATO_0000029 measure of central tendency The geometric mean is defined as the nth root of the product of n numbers, i.e., for a set of numbers \{x_i\}_{i=1}^N, the geometric mean is defined as \left(\prod_{i=1}^N x_i\right)^{1/N}.
http://purl.obolibrary.org/obo/STATO_0000397 harmonic mean http://purl.obolibrary.org/obo/STATO_0000029 measure of central tendency The harmonic mean is a kind of mean which is calculated by dividing the total number of observations by the reciprocal of each number in a series.
Harmonic Mean = N/(1/a1+1/a2+1/a3+1/a4+.......+1/aN)
where a(i)= Individual score and N = Sample size (Number of scores)
http://purl.obolibrary.org/obo/STATO_0000398 weighted arithmetic mean http://purl.obolibrary.org/obo/STATO_0000029 measure of central tendency The weighted arithmetic mean is a kind of mean similar to an ordinary arithmetic mean (the most common type of average), except that instead of each of the data points contributing equally to the final average, some data points contribute more than others.
The weighted arithmetic mean is often used if one wants to combine average values from samples of the same population with different sample sizes.
http://purl.obolibrary.org/obo/STATO_0000401 sample mean http://purl.obolibrary.org/obo/OBI_0000679 average value the sample mean of sample of size n with n observations is an arithmetic mean computed over n number of observations on a statistical sample.
The sample mean, denoted x¯ and read “x-bar,” is simply the average of the n data points x1, x2, ..., xn:
x¯=x1+x2+⋯+xnn=1n∑i=1nxi
The sample mean summarizes the "location" or "center" of the data.
the sample mean is a measure of dispersion of the observations made on the sample and provides an unbias estimate of the population mean
http://purl.obolibrary.org/obo/STATO_0000402 population mean http://purl.obolibrary.org/obo/STATO_0000029 measure of central tendency the population mean or distribution mean is a parameter of a probability distribution or population indicative of the data dispersion. For continous probabibility distribution, the population mean is computed using the probability density function, for discrete probability distributions, a mass density function is used instead.
A population mean can be estimated by computing a sample mean
http://purl.obolibrary.org/obo/STATO_0000405 unstructured covariance structure http://purl.obolibrary.org/obo/STATO_0000346 covariance structure A covariance structure where no restrictions are made on the covariance between any pair of measurements.
http://purl.obolibrary.org/obo/GO_0003674 molecular_function http://purl.obolibrary.org/obo/BFO_0000034 function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
http://purl.obolibrary.org/obo/GO_0003824 catalytic activity http://purl.obolibrary.org/obo/GO_0003674 molecular_function Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
http://purl.obolibrary.org/obo/GO_0008150 biological_process http://purl.obolibrary.org/obo/BFO_0000007 process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
http://purl.obolibrary.org/obo/GO_0010467 gene expression http://purl.obolibrary.org/obo/GO_0008150 biological_process The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.
http://purl.obolibrary.org/obo/GO_0043234 protein complex http://purl.obolibrary.org/obo/BFO_0000040 material entity Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.
http://purl.obolibrary.org/obo/CARO_0001008 gross anatomical part http://purl.obolibrary.org/obo/BFO_0000040 material entity Anatomical structure that is part of a multicellular organism and is at the gross anatomical level, e.g. above the level of a cell. Included are portions of organism substances such as blood, multi-cell-part structures such as axon tracts, acellular anatomical structures such as hair, and organism subdivisions such as head. Excluded is the whole organism and more granular parts of the organism, such as atoms, molecules, macromolecular complexes and cells.
http://purl.obolibrary.org/obo/BFO_0000007 process http://purl.obolibrary.org/obo/BFO_0000003 occurrent A processual entity that is a maximally connected spatiotemporal whole and has bona fide beginnings and endings corresponding to real discontinuities.
http://purl.obolibrary.org/obo/STATO_0000282 F-statistic http://purl.obolibrary.org/obo/STATO_0000039 statistic F statistic is a statistic computed from observations and used to produce a p-value in statistical test when compared to a F distribution. the F statistic is the ratio of two scaled sums of squares reflecting different sources of variability
http://purl.obolibrary.org/obo/IAO_0000573 line graph http://purl.obolibrary.org/obo/IAO_0000038 graph line chart
http://purl.obolibrary.org/obo/NCBITaxon_9606 Homo sapiens http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires man
http://purl.obolibrary.org/obo/OBI_0000435 genotyping assay http://purl.obolibrary.org/obo/OBI_0000443 analyte assay genotype profiling, SNP genotyping
http://purl.obolibrary.org/obo/OBI_0001442 q-value http://purl.obolibrary.org/obo/OBI_0000662 error corrected data set FDR adjusted p-value
http://purl.obolibrary.org/obo/NCBITaxon_2 Bacteria http://purl.obolibrary.org/obo/OBI_0100026 organism eubacteria
http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi http://purl.obolibrary.org/obo/NCBITaxon_7742 Vertebrata bony vertebrates
http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota http://purl.obolibrary.org/obo/OBI_0100026 organism eukaryotes
http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi tetrapods
http://purl.obolibrary.org/obo/NCBITaxon_32524 Amniota http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda amniotes
http://purl.obolibrary.org/obo/NCBITaxon_40674 Mammalia http://purl.obolibrary.org/obo/NCBITaxon_32524 Amniota mammals
http://purl.obolibrary.org/obo/NCBITaxon_7742 Vertebrata http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria vertebrates
http://purl.obolibrary.org/obo/OBI_0000427 enzyme http://purl.obolibrary.org/obo/BFO_0000040 material entity
http://purl.obolibrary.org/obo/IAO_0000582 time stamped measurement datum http://purl.obolibrary.org/obo/IAO_0000109 measurement data item
http://purl.obolibrary.org/obo/OBI_0000973 sequence data http://purl.obolibrary.org/obo/IAO_0000109 measurement data item
http://purl.obolibrary.org/obo/IAO_0000401 one dimensional cartesian spatial coordinate datum http://purl.obolibrary.org/obo/IAO_0000400 cartesian spatial coordinate datum
http://purl.obolibrary.org/obo/IAO_0000402 two dimensional cartesian spatial coordinate datum http://purl.obolibrary.org/obo/IAO_0000400 cartesian spatial coordinate datum
http://purl.obolibrary.org/obo/OBI_0000164 cDNA library http://purl.obolibrary.org/obo/OBI_0000731 recombinant vector
http://purl.obolibrary.org/obo/OBI_0400153 droplet sorter http://purl.obolibrary.org/obo/OBI_0000932 material separation device
http://purl.obolibrary.org/obo/NCBITaxon_10239 Viruses http://purl.obolibrary.org/obo/OBI_0100026 organism
http://purl.obolibrary.org/obo/NCBITaxon_2157 Archaea http://purl.obolibrary.org/obo/OBI_0100026 organism
http://purl.obolibrary.org/obo/OBI_0200167 data normalization objective http://purl.obolibrary.org/obo/OBI_0200166 data transformation objective
http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota
http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta
http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_40674 Mammalia
http://purl.obolibrary.org/obo/BFO_0000001 entity
http://purl.obolibrary.org/obo/IAO_0000039 has measurement unit label http://purl.obolibrary.org/obo/BFO_0000051 has part A relation between a value specification and its unit of measurement.
http://purl.obolibrary.org/obo/IAO_0000219 denotes http://purl.obolibrary.org/obo/IAO_0000136 is about denotes is a primitive, instance-level, relation obtaining between an information content entity and some portion of reality. Denotation is what happens when someone creates an information content entity E in order to specifically refer to something. The only relation between E and the thing is that E can be used to 'pick out' the thing. This relation connects those two together. Freedictionary.com sense 3: To signify directly; refer to specifically
http://purl.obolibrary.org/obo/IAO_0000413 is duration of http://purl.obolibrary.org/obo/IAO_0000136 is about relates a process to a time-measurement-datum that represents the duration of the process
http://purl.obolibrary.org/obo/IAO_0000581 has time stamp http://purl.obolibrary.org/obo/BFO_0000051 has part relates a time stamped measurement datum to the time measurement datum that denotes the time when the measurement was taken
http://purl.obolibrary.org/obo/IAO_0000583 has measurement datum http://purl.obolibrary.org/obo/BFO_0000051 has part relates a time stamped measurement datum to the measurement datum that was measured
http://purl.obolibrary.org/obo/OBI_0000293 has_specified_input http://purl.obolibrary.org/obo/BFO_0000057 has participant A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of.
http://purl.obolibrary.org/obo/OBI_0000295 is_specified_input_of http://purl.obolibrary.org/obo/BFO_0000056 participates in A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of.
http://purl.obolibrary.org/obo/OBI_0000299 has_specified_output http://purl.obolibrary.org/obo/BFO_0000057 has participant A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of.
http://purl.obolibrary.org/obo/OBI_0000312 is_specified_output_of http://purl.obolibrary.org/obo/BFO_0000056 participates in A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of.
http://purl.obolibrary.org/obo/OBI_0000643 has grain http://purl.obolibrary.org/obo/BFO_0000051 has part the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car.
http://purl.obolibrary.org/obo/OBI_0000846 is member of organization http://purl.obolibrary.org/obo/STATO_0000114 is member of Relating a legal person or organization to an organization in the case where the legal person or organization has a role as member of the organization.
http://purl.obolibrary.org/obo/OBI_0001927 specifies value of http://purl.obolibrary.org/obo/IAO_0000136 is about A relation between a value specification and an entity which the specification is about.
http://purl.obolibrary.org/obo/OBI_0001938 has value specification http://purl.obolibrary.org/obo/BFO_0000051 has part A relation between an information content entity and a value specification that specifies its value.
http://purl.obolibrary.org/obo/STATO_0000001 declares http://purl.obolibrary.org/obo/IAO_0000136 is about property to indicate that a design declares a variable; the inverse property is 'is declared by'
http://purl.obolibrary.org/obo/STATO_0000403 estimator of http://purl.obolibrary.org/obo/IAO_0000136 is about Relationship between a quantity and a parameter, where the quantity used or evaluated as an estimate of the value of a parameter.
http://purl.obolibrary.org/obo/BFO_0000079 is function of http://purl.obolibrary.org/obo/BFO_0000052 inheres in function_of
http://purl.obolibrary.org/obo/BFO_0000081 is role of http://purl.obolibrary.org/obo/BFO_0000052 inheres in role_of
http://purl.obolibrary.org/obo/BFO_0000052 inheres in http://purl.obolibrary.org/obo/BFO_0000070 s depends on inheres_in
http://purl.obolibrary.org/obo/BFO_0000050 is part of http://purl.obolibrary.org/obo/BFO_0000082 is located in part_of
http://purl.obolibrary.org/obo/IAO_0000407 has coordinate unit label http://purl.obolibrary.org/obo/BFO_0000051 has part
http://purl.obolibrary.org/obo/IAO_0000136 is about is_about is a (currently) primitive relation that relates an information artifact to an entity.
http://purl.obolibrary.org/obo/OBI_0000124 is_supported_by_data The relation between a data item and a conclusion where the conclusion is the output of a data interpreting process and the data item is used as an input to that process
http://purl.obolibrary.org/obo/OBI_0000314 is_proxy_for A relation between continuant instances c1 and c2 where within an experiment/ protocol application, measurement of c1 is used to determine what a measurement of c2 would be.
http://purl.obolibrary.org/obo/OBI_0000417 achieves_planned_objective This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process.
http://purl.obolibrary.org/obo/OBI_0001937 has specified value A relation between a value specification and a number that quantifies it.
http://purl.obolibrary.org/obo/STATO_0000101 has numerator the relationship between a fraction and the number above the line
http://purl.obolibrary.org/obo/STATO_0000129 has value A relationship (data property) between an entity and its value.
http://purl.obolibrary.org/obo/STATO_0000259 has denominator the relationship between a fraction and the number below the line (or divisor)
http://purl.obolibrary.org/obo/STATO_0000004 is declared by property to indicate the variables declared by a design; the inverse property is 'declares'
http://purl.obolibrary.org/obo/STATO_0000102 executes relationship between a planned process and the plan specification that it carries out; it is defined as equivalent to the composed relationship (realizes o concretizes)
http://purl.obolibrary.org/obo/STATO_0000110 assumes values specified by A relation between an entity and a value specification, where the value specification is about the entity.
http://purl.obolibrary.org/obo/STATO_0000114 is member of relationship between an element and a set it belongs to
http://purl.obolibrary.org/obo/STATO_0000115 has member relationship between a set and one of its elements
http://purl.obolibrary.org/obo/STATO_0000205 is denoted by Inverse relation of 'denotes', where denotation is what happens when someone creates an information content entity E in order to specifically refer to something (from 'denotes' definition).
http://purl.obolibrary.org/obo/BFO_0000056 participates in participates_in
http://purl.obolibrary.org/obo/BFO_0000057 has participant has_participant
http://purl.obolibrary.org/obo/BFO_0000054 is realized by realized_by
http://purl.obolibrary.org/obo/BFO_0000051 has part has_part
http://purl.obolibrary.org/obo/BFO_0000053 is bearer of bearer_of
http://purl.obolibrary.org/obo/BFO_0000070 s depends on s_depends_on
http://purl.obolibrary.org/obo/BFO_0000087 has role has_role
http://purl.obolibrary.org/obo/BFO_0000082 is located in located_in
http://purl.obolibrary.org/obo/BFO_0000086 has quality has_quality
http://purl.obolibrary.org/obo/BFO_0000062 is preceded by preceded_by
http://purl.obolibrary.org/obo/BFO_0000085 has function has_function
http://purl.obolibrary.org/obo/BFO_0000055 realizes
http://purl.obolibrary.org/obo/BFO_0000063 precedes
http://purl.obolibrary.org/obo/IAO_0000404 has x coordinate value
http://purl.obolibrary.org/obo/IAO_0000406 has y coordinate value
http://purl.obolibrary.org/obo/RO_0001000 derives from
http://purl.obolibrary.org/obo/BFO_0000058 is concretized as
http://purl.obolibrary.org/obo/BFO_0000059 concretizes