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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
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    <!-- http://purl.obolibrary.org/obo/RO_0002202 -->

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        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label xml:lang="en">develops from</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/BFO_0000002 -->

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    <!-- http://purl.obolibrary.org/obo/CL_0000134 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000134">
        <rdfs:label>mesenchymal stem cell</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000136 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000136">
        <rdfs:label>adipocyte</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BFO_0000002"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000325"/>
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        <ns4:IAO_0000115>A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides.</ns4:IAO_0000115>
        <skos:prefLabel>adipocyte</skos:prefLabel>
        <oboInOwl:hasDbXref>FMA:63880</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0009082</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>adipose cell</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>CALOHA:TS-0012</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>fat cell</oboInOwl:hasExactSynonym>
        <rdfs:seeAlso>https://cellxgene.cziscience.com/cellguide/CL_0000136</rdfs:seeAlso>
        <dcterms:description>A fat cell, also known as an adipocyte, is a specialized type of connective tissue cell responsible for the storage of fat in the body. These cells can be found throughout the body, but are most densely located in adipose tissue, such as the subcutaneous tissue beneath the skin and around organs, and act as the body’s energy storage units.
The primary function of fat cells is to store energy in the form of fat, also known as triglycerides, for use during periods of caloric deficit. When we consume more calories than we use for energy, our bodies convert the excess energy into fat and store it in adipose tissue. 
Fat cells also play a role in regulating energy balance by secreting hormones, such as leptin and adiponectin, which help to regulate appetite and metabolism. Fat calls have also been implicated in the development of obesity-related diseases, such as insulin resistance and type 2 diabetes. 
Finally, fat cells have been found to play a role in the immune system by secreting cytokines, which can either promote or inhibit inflammation depending on the type of cytokine produced.

(This extended description was generated by ChatGPT and reviewed by the CellGuide team, who added references, and by the CL editors, who approved it for inclusion in CL. It may contain information that applies only to some subtypes and species, and so should not be considered definitional.)</dcterms:description>
        <oboInOwl:hasDbXref>BTO:0000443</oboInOwl:hasDbXref>
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    <!-- http://purl.obolibrary.org/obo/CL_0000325 -->

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        <rdfs:label>stuff accumulating cell</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CL_0002320 -->

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        <rdfs:label>connective tissue cell</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9606 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606">
        <rdfs:label>Homo sapiens</rdfs:label>
    </Class>
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