has plasma membrane part
develops from
develops from
capable of
capable of
Langerhans cell
Originally described in the dendritic cell ontology (DC_CL:0000021 )(PMID:19243617). These cells are also CD1a-high, CD14-negative, CD207-positive (langerin), CD324-positive (E-cadherin), and DCIR-positive. They reside in the epidermis.
BTO:0000705
FMA:63072
CALOHA:TS-2375
Langerhans cell is a conventional dendritic cell that has plasma membrane part CD207. A Langerhans cell is a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus.
LC
MESH:D007801
myeloid cell
myeloid leukocyte
conventional dendritic cell
regulation of type 2 immune response
Homo sapiens
C-type lectin domain family 4 member K