Gene_Product_Is_Element_In_Pathway
Gene_Product_Has_Chemical_Classification
Gene_Product_Has_Organism_Source
Gene_Product_Has_Associated_Anatomy
Gene_Product_Has_Structural_Domain_Or_Motif
Gene_Product_Plays_Role_In_Biological_Process
Gene_Product_Encoded_By_Gene
CTRP Terminology
Plasma Membrane
EGF-Like Domain
Human
CTRP Biomarker Terminology
CTRP Molecular Genetic Biomarker Terminology
Cell Adhesion Molecule
L-Selectin
153240
Amino Acid, Peptide, or Protein
C0125090
C17512
CD62 Antigen Ligand
CD62 Antigen-Like Family Member L
CD62L
CD62L Antigen
CTRP
Cell adhesion molecule and CD antigen that serves as a homing receptor for lymphocytes to lymph node high endothelial venules.
L-Selectin
L-Selectin
L-Selectin
L-Selectin is a cell surface glycoprotein adhesion molecule that serves as a homing receptor for lymphocytes to lymph node high endothelial venules. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to C3/C4 binding protein consensus repeat units. L-Selectin may also play a role in neutrophil adhesion to endothelium at sites of inflammation. A tissue-specific mucin-like endothelial glycoprotein appears to function as ligand for L-selectin, in the role of scaffold that presents carbohydrates to the L-selectin lectin domain. PLAUR is directly associated with the carbohydrate-binding domain of L-selectin in the membrane of neutrophils, an association analogous to that between PLAUR and beta-2 integrins.
L-selectin (372 aa, ~42 kDa) is encoded by the human SELL gene. This protein plays a role in leukocyte adhesion and rolling.
LAM-1
LECAM1
Leukocyte Adhesion Molecule 1
Leukocyte Surface Antigen Leu-8
Leukocyte-Endothelial Cell Adhesion Molecule 1
Lymph Node Homing Receptor
Lymphocyte Adhesion Molecule 1
P14151
Pln Homing Receptor
Receptor
SELL
Selectin L
Selectin-L
TQ1
gp90-MEL
Selectin
Immune Response Process
SELL Gene
Sushi Domain
Lymphocyte Adhesion Pathway
Cell Adhesion Process
Cell Adhesion Molecule Signaling Pathway