Gene_Product_Is_Element_In_Pathway
Gene_Product_Has_Chemical_Classification
Gene_Product_Has_Associated_Anatomy
Gene_Product_Has_Structural_Domain_Or_Motif
Gene_Product_Plays_Role_In_Biological_Process
Gene_Product_Encoded_By_Gene
CTRP Terminology
Endothelial Cell
Transmembrane Domain
EGF-Like Domain
CTRP Biomarker Terminology
CTRP Molecular Genetic Biomarker Terminology
Cell Adhesion Molecule
Transmembrane Protein
P-Selectin
173610
Amino Acid, Peptide, or Protein
C17522
C2742134
CD62
CD62 Antigen-Like Family Member P
CD62P Antigen
CTRP
GMP-140
GMP140
Granule Membrane Protein 140
Granulocyte Membrane Protein
LECAM3
Leukocyte-Endothelial Cell Adhesion Molecule 3
P-Selectin
P-Selectin
P-Selectin
P-Selectin
P-Selectin is a cell surface adhesion molecule that mediates the interaction of activated endothelial cells or platelets with neutrophils and monocytes. The protein is detected in megakaryocytes and platelets, as well as in vascular endothelial cells, but not in other cell types. In endothelia, the protein is localized to the membranes of Weibel-Palade bodies, intracellular storage granules for von Willebrand factor. CD24 is a ligand for P-selectin. Sorting nexin-17 interacts with the cytosolic domain of P-selectin and may function in the intracellular trafficking of P-selectin.
P-selectin (830 aa, ~91 kDa) is encoded by the human SELP gene. This protein plays a role in leukocyte adhesion to myeloid cells, endothelial cells or platelets.
P16109
PADGEM
Platelet Activation Dependent Granule-External Membrane Protein
Platelet Alpha-Granule Membrane Protein
SELP
Selectin
SELP Gene
Sushi Domain
Alpha Granule
Platelet Aggregation Pathway
Granulocyte Adhesion Pathway
Local Acute Inflammatory Response Pathway
Cell Adhesion Process
Monocyte Phagocytosis and Adhesion Pathway
Cell Adhesion Molecule Signaling Pathway
Malaria Pathway