Gene_Product_Is_Element_In_Pathway
Gene_Product_Is_Physical_Part_Of
Gene_Product_Has_Biochemical_Function
Gene_Product_Plays_Role_In_Biological_Process
Gene_Product_Encoded_By_Gene
CTRP Terminology
CTRP Biomarker Terminology
CTRP Molecular Genetic Biomarker Terminology
Ku Protein
X-Ray Repair Cross-Complementing Protein 6
152690
5'-Deoxyribose-5-Phosphate Lyase Ku70
5'-dRP Lyase Ku70
70 kDa Subunit of Ku Antigen
ATP-Dependent DNA Helicase 2 Subunit 1
ATP-Dependent DNA Helicase II 70 kDa Subunit
Amino Acid, Peptide, or Protein
C20023
CL599582
CTC Box Binding Factor 75 kDa Subunit
CTC Box-Binding Factor 75 kDa Subunit
CTC75
CTRP
DNA Repair Protein XRCC6
EC 3.6.4.-
EC 4.2.99.-
Enzyme
G22P1
Ku Autoantigen p70 Subunit
Ku70
Ku70 Protein
Ku70_Protein
Lupus Autoantigen p70
Lupus Ku Autoantigen Protein p70
P12956
Thyroid Autoantigen 70kD
Thyroid-Lupus Autoantigen
Thyroid-Lupus Autoantigen p70
X-Ray Repair Complementing Defective Repair In Chinese Hamster Cells 6
X-Ray Repair Cross-Complementing Protein 6
X-Ray Repair Cross-Complementing Protein 6
X-Ray Repair Cross-Complementing Protein 6
X-ray repair cross-complementing protein 6 (609 aa, ~70 kDa) is encoded by the human XRCC6 gene. This protein plays a role in DNA non-homologous end joining, which is required for both double-strand break repair and V(D)J recombination.
X-ray repair cross-complementing protein 6 is found in a heterodimeric complex with X-ray repair cross-complementing protein 5 to form the DNA helicase II complex (Ku).
Telomere Maintenance
Nonhomologous DNA End Joining
Helicase
XRCC6 Gene
V(D)J Recombination
DNA Repair Protein
Telomere Pathway
Non-Homologous End-Joining Pathway
BARD1 Signaling Pathway
Coregulation Pathway for Androgen Receptor Activity
Telomerase Regulation Pathway
HDAC Class III Signaling Pathway