Gene_Is_Element_In_Pathway
Gene_Has_Physical_Location
Gene_In_Chromosomal_Location
CTRP Terminology
5q13
CTRP Biomarker Terminology
CTRP Molecular Genetic Biomarker Terminology
F2R Gene
Acute Myocardial Infarction Pathway
Extrinsic Prothrombin Activation Pathway
Fibrinolysis Pathway
Intrinsic Prothrombin Activation Pathway
PPAR-alpha Gene Regulation Pathway
Aspirin Inhibition of Platelet Activation Pathway
Thrombin/Protease-Activated Receptor Signaling Pathway
5: 76047542-76067054
F2R wt Allele
187930
2149
C1705939
C51443
CF2R
CTRP
Coagulation Factor II (Thrombin) Receptor wt Allele
Coagulation Factor II Receptor
F2R wt Allele
F2R wt Allele
F2R wt Allele
F2R_wt_Allele
Gene or Genome
HTR
Human F2R wild-type allele is located within 5q13 and is approximately 20 kb in length. This allele, which encodes proteinase-activated receptor 1 protein, is involved in the regulation of the thrombotic response.
NM_001992
PAR-1
PAR1
STAT protein nuclear translocation
TR
apoptosis
blood coagulation
caspase activation
development
extracellular space
proteolysis and peptidolysis
regulation of cell cycle
response to wounding
serine-type peptidase activity
soluble fraction
thrombin activity
tyrosine phosphorylation of STAT protein
Actin Cytoskeleton Regulation Pathway
Neuroactive Ligand-Receptor Signaling Pathway
Calcium-Mediated Signaling Pathway
Endocytosis Pathway
Complement and Coagulation Cascade