Gene_Is_Element_In_Pathway
Gene_In_Chromosomal_Location
Gene_Found_In_Organism
Human
2q12
ZAP70 Gene
CSK Protein Kinase Activation Pathway
T-Cell Apoptosis Pathway
TCR Activation Pathway
T Cell Receptor Signaling Pathway BioCarta
ZAP70 wt Allele
176947
7535
ATP binding
C1705831
C52231
Gene or Genome
Human ZAP70 wild-type allele is located within 2q12 and is approximately 26 kb in length. This allele, which encodes ZAP70 protein, plays a role in the mediation of signal transduction involving cellular effectors in lymphocyte activation. ZAP70 ab gene aberrations cause Selective T-Cell Defect disease.
NM_001079
SRK
STD
ZAP-70
ZAP-70 Gene
ZAP-70_wt_Allele
ZAP70
ZAP70 wt Allele
ZAP70 wt Allele
Zeta-Chain (TCR) Associated Protein Kinase 70kDa wt Allele
Zeta-Chain Associated Protein Kinase
immune response
protein amino acid phosphorylation
protein binding
protein kinase cascade
protein tyrosine kinase activity
Natural Killer Cell-Mediated Cytotoxicity Pathway
T Cell Receptor Signaling Pathway KEGG
Primary Immunodeficiency Pathway
T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells
T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells