<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/UBERON?iri=http://purl.obolibrary.org/obo/UBERON_0000948"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:core="http://purl.obolibrary.org/obo/uberon/core#"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/UBPROP_0000007"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/UBPROP_0000003"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/UBPROP_0000002"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/UBPROP_0000001"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002161"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/uberon/core#human_subset"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasNarrowSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/uberon/core#efo_slim"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/uberon/core#major_organ"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/uberon/core#organ_slim"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/uberon/core#uberon_slim"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/uberon/core#vertebrate_core"/>
    <AnnotationProperty rdf:about="http://xmlns.com/foaf/0.1/depiction"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/uberon/core#pheno_slim"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/uberon/core#mouse_subset"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002175"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/BFO_0000050 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000050">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>part of</rdfs:label>
        <rdfs:label xml:lang="en">part of</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>has part</rdfs:label>
        <rdfs:label xml:lang="en">has part</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002162 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002162">
        <rdfs:label>in taxon</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002202 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002202">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label>develops from</rdfs:label>
        <rdfs:label xml:lang="en">develops from</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002254 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002254">
        <rdfs:label>has developmental contribution from</rdfs:label>
        <rdfs:label xml:lang="en">has developmental contribution from</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002433 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002433">
        <rdfs:label>contributes to morphology of</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_6239 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_6239">
        <rdfs:label>Caenorhabditis elegans</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_7227 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_7227">
        <rdfs:label>Drosophila melanogaster</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_7742 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_7742">
        <rdfs:label>Vertebrata &lt;vertebrates&gt;</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9606 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606">
        <rdfs:label>Homo sapiens</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000948 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000948">
        <rdfs:label>heart</rdfs:label>
        <equivalentClass>
            <Class>
                <intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/UBERON_0007100"/>
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004151"/>
                    </Restriction>
                </intersectionOf>
            </Class>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004120"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0005181"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0007100"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/UBERON_0010314"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004151"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002433"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004535"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <someValuesFrom>
                    <Class>
                        <complementOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7227"/>
                    </Class>
                </someValuesFrom>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <someValuesFrom>
                    <Class>
                        <complementOf rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6239"/>
                    </Class>
                </someValuesFrom>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002254"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002342"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000050"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0015410"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002202"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004141"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7742"/>
            </Restriction>
        </rdfs:subClassOf>
        <disjointWith>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7227"/>
            </Restriction>
        </disjointWith>
        <disjointWith>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002162"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6239"/>
            </Restriction>
        </disjointWith>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://cdn.humanatlas.io/digital-objects/ref-organ/heart-female/v1.3/assets/3d-vh-f-heart.glb</foaf:depiction>
        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://cdn.humanatlas.io/digital-objects/ref-organ/heart-male/v1.3/assets/3d-vh-m-heart.glb</foaf:depiction>
        <oboInOwl:id>UBERON:0000948</oboInOwl:id>
        <oboInOwl:hasDbXref>EHDAA:420</oboInOwl:hasDbXref>
        <ns4:UBPROP_0000003>As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[well established][VHOG]</ns4:UBPROP_0000003>
        <oboInOwl:hasDbXref>MA:0000072</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BILA:0000020</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIAA:0000036</oboInOwl:hasDbXref>
        <ns4:UBPROP_0000001>Part of the circulatory system responsible for pumping blood; composed of three chambers--two atria and one ventricle.[AAO]</ns4:UBPROP_0000001>
        <oboInOwl:hasDbXref>NCIT:C12727</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>TAO:0000114</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BTO:0000562</oboInOwl:hasDbXref>
        <ns4:UBPROP_0000002>relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO]</ns4:UBPROP_0000002>
        <oboInOwl:hasDbXref>MESH:D006321</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0000815</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0000114</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-0445</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GAID:174</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>chambered heart</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>vertebrate heart</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>VHOG:0000276</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MAT:0000036</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EHDAA2:0000738</oboInOwl:hasDbXref>
        <ns4:IAO_0000115>A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ.</ns4:IAO_0000115>
        <oboInOwl:hasNarrowSynonym>branchial heart</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>Wikipedia:Heart</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EV:0100018</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>galen:Heart</oboInOwl:hasDbXref>
        <rdfs:comment>Taxon notes:&quot; the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)&quot; DOI:10.1101/gad.1485706</rdfs:comment>
        <oboInOwl:hasDbXref>SCTID:302509004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:16105</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0018787</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>AAO:0010210</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:7088</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>XAO:0000064</oboInOwl:hasDbXref>
        <ns4:UBPROP_0000001>Blood pumping organ composed of four chambers: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus.[TAO]</ns4:UBPROP_0000001>
        <oboInOwl:hasRelatedSynonym>cardium</oboInOwl:hasRelatedSynonym>
        <ns4:UBPROP_0000007>cardiac</ns4:UBPROP_0000007>
        <ns4:RO_0002161 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_6239"/>
        <ns4:RO_0002161 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_7227"/>
        <ns4:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#efo_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#human_subset"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#major_organ"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#mouse_subset"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#organ_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#pheno_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#uberon_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#vertebrate_core"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002342 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002342">
        <rdfs:label>neural crest</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0004120 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0004120">
        <rdfs:label>mesoderm-derived structure</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0004141 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0004141">
        <rdfs:label>heart tube</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0004151 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0004151">
        <rdfs:label>cardiac chamber</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0004535 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0004535">
        <rdfs:label>cardiovascular system</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0005181 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0005181">
        <rdfs:label>thoracic segment organ</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0007100 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0007100">
        <rdfs:label>primary circulatory organ</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0010314 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0010314">
        <rdfs:label>structure with developmental contribution from neural crest</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0015410 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0015410">
        <rdfs:label>heart plus pericardium</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



