Term IRI Term label Parent term IRI Parent term label Alternative term Definition http://purl.obolibrary.org/obo/PLANA_0007547 anterior pole progenitor cell http://purl.obolibrary.org/obo/PLANA_0000429 neoblast piwi-1+, foxD+, prep+ progenitor neoblasts required for formation of the anterior pole. http://purl.obolibrary.org/obo/GO_0062125 regulation of mitochondrial gene expression http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). http://purl.obolibrary.org/obo/PLANP_0000811 scorpion tail http://purl.obolibrary.org/obo/PLANP_0000036 abnormal tail Any structural anomaly that causes dorsal region of tail to be curled shaped. http://purl.obolibrary.org/obo/PLANP_0000812 abnormally inchworming http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype An anomaly in inchworming behavior. http://purl.obolibrary.org/obo/PLANP_0000815 immobile animal http://purl.obolibrary.org/obo/PLANP_0000795 stationary animal anomaly in the complete lack of the ability to move of whole organism. http://purl.obolibrary.org/obo/GO_0140013 meiotic nuclear division http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process One of the two nuclear divisions that occur as part of the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0140056 organelle localization by membrane tethering http://purl.obolibrary.org/obo/GO_0051640 organelle localization The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other. http://purl.obolibrary.org/obo/PLANA_0000131 primordium http://purl.obolibrary.org/obo/UBERON_0007567 regenerating anatomical structure Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue. http://purl.obolibrary.org/obo/PLANA_0000133 mechanoreceptor cell http://purl.obolibrary.org/obo/PLANA_0000552 sensory neuron A cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. http://purl.obolibrary.org/obo/PLANA_0000201 bursal canal http://purl.obolibrary.org/obo/PLANA_0000113 tissue The passageway connecting the genital atrium to the copulatory bursa. Part of the copulatory apparatus. During mating, sperm from a partner is deposited into the bursal canal, where it collects in the copulatory bursa before travelling up the oviducts to the tuba. http://purl.obolibrary.org/obo/PLANA_0000203 gonopore http://purl.obolibrary.org/obo/PLANA_0002079 pore The gonopore, a component of the copulatory apparatus, is an opening located on the ventral side of the animal posterior to the pharynx. The gonopore is the sole point of exit and entry for the reproductive system, allowing from reciprocal exchange of sperm during copulation and egg capsule laying. http://purl.obolibrary.org/obo/PLANA_0000204 ovary http://purl.obolibrary.org/obo/BFO_0000040 material entity A gonad containing female germline stem cells which fuel oocyte production. Two ovaries are located ventally, underneath the body wall musculature, immediately posterior to the cephalic ganglia (brain) and adjacent to the ventral nerve cords. The neoblast compartment, including piwi-1+, nanos+ primordial germ cells, fuel formation of the ovaries during juvenile development. http://purl.obolibrary.org/obo/PLANA_0000205 oviduct http://purl.obolibrary.org/obo/PLANA_0002089 reproductive organ Ciliated tubes adjacent to the ventral nerve cords, adjoining the tuba and the bursal canal, that transport fertilized oocytes to the genital atrium. http://purl.obolibrary.org/obo/PLANA_0000206 penis papilla http://purl.obolibrary.org/obo/PLANA_0002089 reproductive organ A rounded protuberance, connected to the seminal vesicles, responsible for transferring semen into a mating partner's bursal canal. http://purl.obolibrary.org/obo/PLANA_0000207 sperm duct http://purl.obolibrary.org/obo/PLANA_0002089 reproductive organ A network of tubes that transport sperm from the testes to the seminal vesicles. Tubes connect each testis to ducts that run along the ventral nerve cords. The ducts bifurcate immediately posterior to the pharynx, where they connect to the seminal vesicles. http://purl.obolibrary.org/obo/PLANA_0000208 testis http://purl.obolibrary.org/obo/BFO_0000040 material entity A gonad containing male germline stem cells which fuel sperm production. Testes are located dorsolaterally, and are excluded from the head. The neoblast compartment, including piwi-1+, nanos+ primordial germ cells, fuels formation of testes during juvenile development and regeneration. http://purl.obolibrary.org/obo/PLANA_0000211 primitive ectoderm cell http://purl.obolibrary.org/obo/PLANA_0004518 extraembryonic cell Primitive ectoderm cells differentiate from the blastomere population, exit the cell cycle and interact to boud the embryo during Stage 2. http://purl.obolibrary.org/obo/PLANA_0000214 juvenile http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A sexually immature member of the Schmidtea mediterranea sexuallly reproducing biotype. http://purl.obolibrary.org/obo/PLANA_0000215 reproductive system product http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Products of the reproductive system include gametes, zygotes, yolk cells and egg capsules. http://purl.obolibrary.org/obo/PLANA_0000216 egg capsule http://purl.obolibrary.org/obo/PLANA_0000215 reproductive system product A proteinaceous, semi-permeable shell housing yolk cells and one or more embryos.Egg capsules are anchored to a substrate via a stalk. http://purl.obolibrary.org/obo/PLANA_0000217 gonad http://purl.obolibrary.org/obo/PLANA_0002089 reproductive organ Reproductive organ that produces and releases eggs (ovary) or sperm (testis). http://purl.obolibrary.org/obo/PLANA_0000218 male primordial germ cell http://purl.obolibrary.org/obo/PLANA_0000121 stem cell Cells coexpressing piwi-1 and nanos that are required for male gonad formation. Primordial germ cells are present in both asexual adults and sexual hermaphrodites. This term may be redundant with spermatogonial stem cell. http://purl.obolibrary.org/obo/PLANA_0000219 spermatogonial stem cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity gh4+, nanos+ cells residing at the testis periphery that self-renew and give rise to differentiating daughters that will ultimately produce haploid sperm. http://purl.obolibrary.org/obo/PLANA_0000220 spermatogonium http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity An euploid male germ cell of an early stage of spermatogenesis. In planaria, the gh4+ stem cell daughter exiting the niche undergoes three rounds of transit amplifying division with incomplete cytokinesis prior to transitioning to terminal differentiation. http://purl.obolibrary.org/obo/PLANA_0000221 spermatocyte http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A tektin-1+ male germ cell that develops from spermatogonia. The euploid primary spermatocytes undergo meiosis and give rise to the haploid secondary spermatocytes which in turn give rise to spermatids. http://purl.obolibrary.org/obo/PLANA_0000222 spermatid http://purl.obolibrary.org/obo/BFO_0000040 material entity A male germ cell that develops from the haploid secondary spermatocytes. Without further division, spermatids undergo structural changes and give rise to spermatozoa. http://purl.obolibrary.org/obo/PLANA_0000223 oogonial stem cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A piwi-1+, nanos+ cell residing in the ovary that self-renews and give rise to oogonial cells that differentiate into oocytes. http://purl.obolibrary.org/obo/PLANA_0000224 cement gland http://purl.obolibrary.org/obo/PLANA_0000113 tissue Glands surrounding the genital atrium that are required for production of the proteinaceous egg capsule shell and stalk. http://purl.obolibrary.org/obo/PLANA_0000227 germ cell http://purl.obolibrary.org/obo/PLANA_0000499 cell 1. A gamete (as an egg or sperm cell) or one of its antecedent cells. 2. A mature male or female germ cell usually possessing a haploid chromosome set and capable of initiating formation of a new diploid individual by fusion with a gamete of the opposite sex. http://purl.obolibrary.org/obo/PLANA_0000228 male germ cell http://purl.obolibrary.org/obo/PLANA_0000227 germ cell A male germ cell is a germ cell that supports male gamete production. http://purl.obolibrary.org/obo/PLANA_0000229 female germ cell http://purl.obolibrary.org/obo/PLANA_0000227 germ cell Female germ cell is a germ cell that supports female gamete production. http://purl.obolibrary.org/obo/PLANA_0000230 tuba http://purl.obolibrary.org/obo/PLANA_0002089 reproductive organ A sperm storage organ located immediately posterior to the ovary, at the anterior end of the oviduct. Oocytes exiting the ovary are fertilized in the tuba as they enter the oviduct. http://purl.obolibrary.org/obo/PLANA_0000231 vitelline gland http://purl.obolibrary.org/obo/PLANA_0000113 tissue Glands surrounding the oviducts which produce yolk cells. Yolk cells deposited into the oviducts travel to the genital atrium where they are packaged, along with one or more zygotes, into developing egg capsules. http://purl.obolibrary.org/obo/PLANA_0000232 copulatory apparatus http://purl.obolibrary.org/obo/PLANA_0002090 reproductive structure Accessory reproductive structures involved in copulation, egg capsule development and laying. http://purl.obolibrary.org/obo/PLANA_0000233 copulatory bursa http://purl.obolibrary.org/obo/PLANA_0002089 reproductive organ An organ that receives and stores sperm from mating partners. http://purl.obolibrary.org/obo/PLANA_0000234 seminal vesicle http://purl.obolibrary.org/obo/PLANA_0002089 reproductive organ Glandular pouches adjoining the sperm ducts which produce seminal fluid. http://purl.obolibrary.org/obo/PLANA_0000237 round spermatid http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A cyst of 8 interconnected spermatocytes undergoes meiosis, producing 32 haploid round spermatids. Round spermatids express protein kinase A, andundergo morphogenesis to produce mature sperm. http://purl.obolibrary.org/obo/PLANA_0000238 elongate spermatid http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity Spermatids expressing protein kinase A undergoing morphogenic changes to make mature sperm. http://purl.obolibrary.org/obo/PLANA_0000239 oogonial cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes. http://purl.obolibrary.org/obo/PLANA_0000240 body wall musculature http://purl.obolibrary.org/obo/BFO_0000040 material entity Any collection of muscles that is part of a body wall [Automatically generated definition]. http://purl.obolibrary.org/obo/PLANA_0000241 pharynx longitudinal muscle cell http://purl.obolibrary.org/obo/PLANA_0000101 muscle cell Pharynx muscle fibers running anteroposterior (proximal to distal). http://purl.obolibrary.org/obo/PLANA_0000404 pharynx lumen http://purl.obolibrary.org/obo/PLANA_0002053 lumen Anatomical space enclosed by the pharynx inner epithelium. http://purl.obolibrary.org/obo/PLANA_0000405 digestive tract lumen http://purl.obolibrary.org/obo/PLANA_0002053 lumen An anatomical space that is surrounded by a digestive tract. http://purl.obolibrary.org/obo/PLANA_0000406 oral opening http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity The orifice that connects the mouth to the exterior of the body. http://purl.obolibrary.org/obo/PLANA_0000407 pharynx pouch cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity Anatomical space between the pharynx and the epithelial cells comprising parapharyngeal pouch. http://purl.obolibrary.org/obo/PLANA_0000409 apical surface of the epidermis http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The apical surface of the single layered epidermis that is in contact with the environment. http://purl.obolibrary.org/obo/PLANA_0000410 basal surface of the epidermis http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The basal surface of the epidermis in direct contact with the basal lamina. http://purl.obolibrary.org/obo/PLANA_0000411 gastrodermis surface http://purl.obolibrary.org/obo/BSPO_0000005 anatomical surface The surface of the gastrodermis in contact with the gut lumen. http://purl.obolibrary.org/obo/PLANA_0000412 pharynx inner epithelium surface http://purl.obolibrary.org/obo/BSPO_0000005 anatomical surface The epithelial surface lining the interior of the pharynx, facing the lumen. http://purl.obolibrary.org/obo/PLANA_0000413 pharynx outer epithelium surface http://purl.obolibrary.org/obo/BSPO_0000005 anatomical surface Epithelial surface covering the outside of the pharynx. http://purl.obolibrary.org/obo/PLANA_0000414 pharynx pouch epithelial surface http://purl.obolibrary.org/obo/BSPO_0000005 anatomical surface The surface of the parapharyngeal pouch facing the pharynx. http://purl.obolibrary.org/obo/PLANA_0000417 definitive organism subdivision http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision Anatomical structure which is a subdivision of a whole adult or juvenile organism, consisting of components of multiple anatomical systems. http://purl.obolibrary.org/obo/PLANA_0000418 head http://purl.obolibrary.org/obo/PLANA_0000102 anatomical region The head is the anterior-most division of the body [GO]. A three dimensional compartment bounded by the anterior margin or the head and the posterior boundary of the cephalic ganglia (brain). http://purl.obolibrary.org/obo/PLANA_0000419 prepharyngeal region http://purl.obolibrary.org/obo/PLANA_0000102 anatomical region Region of the juvenile or adult animal between the posterior end of the cephalic ganglia and the anterior end of the pharynx. http://purl.obolibrary.org/obo/PLANA_0000420 parapharyngeal region http://purl.obolibrary.org/obo/PLANA_0000102 anatomical region Region of the animal lateral to and surrounding the pharynx. http://purl.obolibrary.org/obo/PLANA_0000421 tail http://purl.obolibrary.org/obo/PLANA_0000102 anatomical region Caudal region, beginning at the mouth and ending at posterior pole. http://purl.obolibrary.org/obo/PLANA_0000422 tail stripe http://purl.obolibrary.org/obo/PLANA_0000102 anatomical region Medial region of the tail; the parenchymal space between the posterior primary gut branches. http://purl.obolibrary.org/obo/PLANA_0000423 embryonic subdivision http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision Anatomical structure which is a subdivision of a whole developing/ embryonic organism, consisting of components of multiple anatomical systems. http://purl.obolibrary.org/obo/PLANA_0000427 multicellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that has more than one cell as a part. http://purl.obolibrary.org/obo/PLANA_0000428 musculature system http://purl.obolibrary.org/obo/PLANA_0000114 anatomical system Total musculature of the planarian body. http://purl.obolibrary.org/obo/PLANA_0000429 neoblast http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A heterogeneous population of pluripotent, somatic adult stem cells and lineage primed progenitors that are required for maintenance and regeneration of all cell types in planaria, including the germline. http://purl.obolibrary.org/obo/PLANA_0000430 epithelial cell component http://purl.obolibrary.org/obo/GO_0005575 cellular_component A part of an epithelial cell. http://purl.obolibrary.org/obo/PLANA_0000431 organ http://purl.obolibrary.org/obo/PLANA_0000427 multicellular anatomical structure Anatomical structure that performs a specific function or group of functions. http://purl.obolibrary.org/obo/PLANA_0000459 optic chiasm http://purl.obolibrary.org/obo/BFO_0000040 material entity A decussation of the diencephalon where the fibers of the optic nerve cross http://purl.obolibrary.org/obo/PLANA_0000460 anterior commissure http://purl.obolibrary.org/obo/PLANA_0000494 brain commissure A bundle of nerve fibers connecting the two cephalic ganglia. http://purl.obolibrary.org/obo/PLANA_0000461 lateral branch http://purl.obolibrary.org/obo/PLANA_0000113 tissue Nerve branches that extend from the lateral side of each cephalic ganglia lobe. Each lobe has nine lateral branches which terminate in sensory organs. Evidence suggests they play a role in chemosensation. http://purl.obolibrary.org/obo/PLANA_0000462 sensory cell http://purl.obolibrary.org/obo/PLANA_0000119 terminally differentiated cell A cell that performs a sensory function. http://purl.obolibrary.org/obo/PLANA_0000463 cholinergic neuron http://purl.obolibrary.org/obo/PLANA_0000556 neurosecretory neuron Neurons that express choline acetyltransferase. http://purl.obolibrary.org/obo/PLANA_0000464 GABAergic neuron http://purl.obolibrary.org/obo/PLANA_0000556 neurosecretory neuron Neurons that express glutamine decarboxylase. http://purl.obolibrary.org/obo/PLANA_0000465 pharynx nerve plexus http://purl.obolibrary.org/obo/BFO_0000040 material entity Plexus of nerves located in the pharynx comprised of inner and outer wall rings. http://purl.obolibrary.org/obo/PLANA_0000466 subepidermal nerve plexus http://purl.obolibrary.org/obo/BFO_0000040 material entity Plexus of nerves located just between the epidermis and the body wall musculature. http://purl.obolibrary.org/obo/PLANA_0000467 submuscular nerve plexus http://purl.obolibrary.org/obo/BFO_0000040 material entity Plexus of nerves that innervate the body wall musculature. http://purl.obolibrary.org/obo/PLANA_0000468 gastrodermal plexus http://purl.obolibrary.org/obo/BFO_0000040 material entity A thin net of single nerve fibers located around the gut. http://purl.obolibrary.org/obo/PLANA_0000470 neuropil http://purl.obolibrary.org/obo/PLANA_0000113 tissue A cluster of neurites that is part of a nervous system and forms a network of dendrites and axons where synapses are present and in which neuronal somata do not occur. http://purl.obolibrary.org/obo/PLANA_0000472 pharynx outer epithelium http://purl.obolibrary.org/obo/PLANA_0002023 ciliated epithelium Heavily ciliated epidermal cells covering the outer surface of the pharynx shaft. These are "insunk" epidermal cells in which the nuclei reside behind the layers of longitudinal and circumferential muscles and the epithelial cell body sends out a ciliated projection to the surface to cover and encase the shaft. http://purl.obolibrary.org/obo/PLANA_0000473 pharynx outer circular muscle cell http://purl.obolibrary.org/obo/PLANA_0007535 pharynx circular muscle cell Pharynx muscle fibers thar run circumferentially about the pharynx and lie just beneath the outer longitudinal pharynx muscles. http://purl.obolibrary.org/obo/PLANA_0000474 pharynx inner circular muscle cell http://purl.obolibrary.org/obo/PLANA_0007535 pharynx circular muscle cell Pharynx muscle fiber that runs circumferentially about the pharynx and lies just beneath the inner logitudinal pharynx muscle fibers. http://purl.obolibrary.org/obo/PLANA_0000475 pharynx inner longitudinal muscle cell http://purl.obolibrary.org/obo/PLANA_0000241 pharynx longitudinal muscle cell Pharynx muscle fibers running anteroposterior which lie beneath both the inner circular muscle fibers and the apical, ciliated portion of the epithium lining the lumenal surface. http://purl.obolibrary.org/obo/PLANA_0000476 pharynx outer longitudinal muscle cell http://purl.obolibrary.org/obo/PLANA_0000241 pharynx longitudinal muscle cell Pharynx muscle fibers running anteroposterior which lie just underneath the apical, cilaited portion of the outer epithelium. http://purl.obolibrary.org/obo/PLANA_0000477 pharynx radial muscle cell http://purl.obolibrary.org/obo/PLANA_0000101 muscle cell Pharynx muscle fibers that run radially, connecting the outer muscle fibers and epithelia with their inner counterparts. http://purl.obolibrary.org/obo/PLANA_0000478 pharynx musculature http://purl.obolibrary.org/obo/PLANA_0000113 tissue The total musculature within the pharynx. http://purl.obolibrary.org/obo/PLANA_0000479 pharynx inner nerve plexus http://purl.obolibrary.org/obo/PLANA_0000465 pharynx nerve plexus Ring of the pharynx nerve plexus that is proximal to the lumen. http://purl.obolibrary.org/obo/PLANA_0000480 pharynx outer nerve plexus http://purl.obolibrary.org/obo/PLANA_0000465 pharynx nerve plexus Ring of the pharynx nerve plexus that is proximal to the exterior surface. http://purl.obolibrary.org/obo/PLANA_0000481 serotonergic neuron http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity Neurons that express the neurotransmitter serotonin. http://purl.obolibrary.org/obo/PLANA_0000482 dopaminergic neuron http://purl.obolibrary.org/obo/PLANA_0000556 neurosecretory neuron A neuron that expresses the neurotransmitter dopamine. http://purl.obolibrary.org/obo/PLANA_0000483 octopaminergic neuron http://purl.obolibrary.org/obo/PLANA_0000556 neurosecretory neuron Neurons that express the biogenic amine octopamine. http://purl.obolibrary.org/obo/PLANA_0000484 secretory system http://purl.obolibrary.org/obo/PLANA_0000114 anatomical system Anatomical system that has as its parts cells and glands devoted to the discharge of substances such as mucus. http://purl.obolibrary.org/obo/PLANA_0000485 gland cell http://purl.obolibrary.org/obo/PLANA_0000100 epithelial cell Specialized insunk epithelial cells located in the mesenchyme that participate in mucus secretion. They are characterized by elongated cell bodies with long cytoplasmic projections that terminate between, or penetrate directly throughepithelial cells and form a secretory pore at the surface. http://purl.obolibrary.org/obo/PLANA_0000486 secretory pore http://purl.obolibrary.org/obo/PLANA_0002079 pore The opening by which the gland cells secrete mucus to the exterior of the animal. http://purl.obolibrary.org/obo/PLANA_0000487 acidophilic gland cell http://purl.obolibrary.org/obo/PLANA_0000485 gland cell One of two distinct histochemical classes of gland cells, these can be found throughout the body but primarily form clusters of subepidermal marginal adhesive glands along the dorsoventral border of the animal. http://purl.obolibrary.org/obo/PLANA_0000488 basophilic gland cell http://purl.obolibrary.org/obo/PLANA_0000485 gland cell One of two distinct histochemical classes of gland cells, these are found near the ventral mesenchyme, the pharynx and in the dorsal region of the head. May also be called cyanophilic gland cells. http://purl.obolibrary.org/obo/PLANA_0000492 nerve plexus http://purl.obolibrary.org/obo/PLANA_0000113 tissue Anatomical junction where subdivisions of two or more neural trees interconnect with one another to form a network through which nerve fibers of the constituent nerve trees become regrouped; together with other nerve plexuses, nerves and ganglia, it constitutes the peripheral nervous system. Examples: cervical nerve plexus, brachial nerve plexus, sacral nerve plexus[FMA]. http://purl.obolibrary.org/obo/PLANA_0000494 brain commissure http://purl.obolibrary.org/obo/PLANA_0002025 commissure any of the nerve fiber tracts that span the longitudinal fissure between the cerebral and/or cerebellar hemispheres of the brain http://purl.obolibrary.org/obo/PLANA_0000495 blastema http://purl.obolibrary.org/obo/UBERON_0007567 regenerating anatomical structure A regenerating tissue composed of a proliferative mass of undifferentiated progenitor cells from which new differentiated structures arise. http://purl.obolibrary.org/obo/PLANA_0000499 cell http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. http://purl.obolibrary.org/obo/PLANA_0000501 cell projection http://purl.obolibrary.org/obo/GO_0005575 cellular_component A prolongation or process extending from a cell. http://purl.obolibrary.org/obo/PLANA_0000502 actin-based cell projection http://purl.obolibrary.org/obo/PLANA_0000501 cell projection A cell projection supported by an assembly of actin filaments. http://purl.obolibrary.org/obo/PLANA_0000504 microvillus http://purl.obolibrary.org/obo/PLANA_0000502 actin-based cell projection Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. http://purl.obolibrary.org/obo/PLANA_0000505 cell-cell contact zone http://purl.obolibrary.org/obo/GO_0005575 cellular_component Extended zone of intimate apposition between two cells containing one or more types of intercellular junctions. http://purl.obolibrary.org/obo/PLANA_0000506 cell junction http://purl.obolibrary.org/obo/PLANA_0000505 cell-cell contact zone A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix. http://purl.obolibrary.org/obo/PLANA_0000507 cell-cell junction http://purl.obolibrary.org/obo/PLANA_0000506 cell junction A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals. http://purl.obolibrary.org/obo/PLANA_0000508 cell-cell adhesion http://purl.obolibrary.org/obo/PLANA_0000505 cell-cell contact zone The attachment of one cell to another cell via adhesion molecules. http://purl.obolibrary.org/obo/PLANA_0000509 intracellular part http://purl.obolibrary.org/obo/GO_0005575 cellular_component Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. http://purl.obolibrary.org/obo/PLANA_0000510 cytoplasm http://purl.obolibrary.org/obo/PLANA_0000509 intracellular part All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures http://purl.obolibrary.org/obo/PLANA_0000513 cytoplasmic part http://purl.obolibrary.org/obo/PLANA_0000509 intracellular part Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. http://purl.obolibrary.org/obo/PLANA_0000514 cytoplasmic vesicle part http://purl.obolibrary.org/obo/PLANA_0000513 cytoplasmic part Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell. http://purl.obolibrary.org/obo/PLANA_0000515 vacuole http://purl.obolibrary.org/obo/PLANA_0000526 membrane-bounded organelle A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. http://purl.obolibrary.org/obo/PLANA_0000518 intracellular organelle http://purl.obolibrary.org/obo/PLANA_0000509 intracellular part Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. http://purl.obolibrary.org/obo/PLANA_0000519 intracellular non-membrane-bounded organelle http://purl.obolibrary.org/obo/PLANA_0000531 non-membrane-bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes http://purl.obolibrary.org/obo/PLANA_0000520 membrane http://purl.obolibrary.org/obo/GO_0005575 cellular_component A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. http://purl.obolibrary.org/obo/PLANA_0000521 bounding membrane of organelle http://purl.obolibrary.org/obo/PLANA_0000520 membrane Examples include the outer membranes of double membrane bound organelles such as mitochondria as well as the bounding membranes of single-membrane bound organelles such as lysosomes. http://purl.obolibrary.org/obo/PLANA_0000522 membrane part http://purl.obolibrary.org/obo/GO_0005575 cellular_component Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. http://purl.obolibrary.org/obo/PLANA_0000523 plasma membrane part http://purl.obolibrary.org/obo/PLANA_0000522 membrane part Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. http://purl.obolibrary.org/obo/PLANA_0000524 organelle membrane http://purl.obolibrary.org/obo/PLANA_0000520 membrane A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. http://purl.obolibrary.org/obo/PLANA_0000525 organelle http://purl.obolibrary.org/obo/GO_0005575 cellular_component Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. http://purl.obolibrary.org/obo/PLANA_0000526 membrane-bounded organelle http://purl.obolibrary.org/obo/PLANA_0000525 organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. http://purl.obolibrary.org/obo/PLANA_0000527 intracellular membrane-bounded organelle http://purl.obolibrary.org/obo/PLANA_0000526 membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. http://purl.obolibrary.org/obo/PLANA_0000528 Golgi apparatus http://purl.obolibrary.org/obo/PLANA_0000527 intracellular membrane-bounded organelle A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions. http://purl.obolibrary.org/obo/PLANA_0000529 nucleus http://purl.obolibrary.org/obo/PLANA_0000527 intracellular membrane-bounded organelle A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. http://purl.obolibrary.org/obo/PLANA_0000530 secretory vesicle http://purl.obolibrary.org/obo/PLANA_0000527 intracellular membrane-bounded organelle A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space. http://purl.obolibrary.org/obo/PLANA_0000531 non-membrane-bounded organelle http://purl.obolibrary.org/obo/PLANA_0000525 organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes. http://purl.obolibrary.org/obo/PLANA_0000532 nuclear part http://purl.obolibrary.org/obo/PLANA_0000509 intracellular part Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. http://purl.obolibrary.org/obo/PLANA_0000533 nucleolus http://purl.obolibrary.org/obo/PLANA_0000532 nuclear part A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. http://purl.obolibrary.org/obo/PLANA_0000534 chromatin http://purl.obolibrary.org/obo/PLANA_0000532 nuclear part The ordered and organized complex of DNA, protein (histones), and sometimes RNA, that forms the chromosome. http://purl.obolibrary.org/obo/PLANA_0000535 heterochromatin http://purl.obolibrary.org/obo/PLANA_0000534 chromatin A compact and highly condensed form of chromatin. http://purl.obolibrary.org/obo/PLANA_0000536 euchromatin http://purl.obolibrary.org/obo/PLANA_0000534 chromatin A dispersed and relatively uncompacted form of chromatin. http://purl.obolibrary.org/obo/PLANA_0000537 ribosome http://purl.obolibrary.org/obo/PLANA_0000519 intracellular non-membrane-bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes. http://purl.obolibrary.org/obo/PLANA_0000538 axon tract http://purl.obolibrary.org/obo/PLANA_0000113 tissue A group of axons linking two or more neuropils and having a common origin, termination http://purl.obolibrary.org/obo/PLANA_0000539 electrically responsive cell http://purl.obolibrary.org/obo/PLANA_0000119 terminally differentiated cell A cell whose function is determined by its response to an electric signal. http://purl.obolibrary.org/obo/PLANA_0000540 electrically signaling cell http://purl.obolibrary.org/obo/PLANA_0000119 terminally differentiated cell A cell that initiates an electrical signal and passes that signal to another cell. http://purl.obolibrary.org/obo/PLANA_0000541 nerve http://purl.obolibrary.org/obo/PLANA_0000113 tissue An enclosed, cable-like bundle of axons in the peripheral nervous system originating in a nerve root in the central nervous system (or a condensed nervous structure) connecting with peripheral structures. http://purl.obolibrary.org/obo/PLANA_0000543 neuron projection bundle http://purl.obolibrary.org/obo/PLANA_0000538 axon tract A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses. http://purl.obolibrary.org/obo/PLANA_0000545 afferent neuron http://purl.obolibrary.org/obo/PLANA_0000099 neuron A neuron which conveys sensory information centrally from the periphery. http://purl.obolibrary.org/obo/PLANA_0000546 bipolar neuron http://purl.obolibrary.org/obo/PLANA_0000550 interneuron A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body. http://purl.obolibrary.org/obo/PLANA_0000547 commissural neuron http://purl.obolibrary.org/obo/PLANA_0000099 neuron A neuron that has an axon which crosses the midline. http://purl.obolibrary.org/obo/PLANA_0000548 efferent neuron http://purl.obolibrary.org/obo/PLANA_0000099 neuron A neuron which sends impulses peripherally to activate muscles or secretory cells. http://purl.obolibrary.org/obo/PLANA_0000549 excitatory motor neuron http://purl.obolibrary.org/obo/PLANA_0000564 peripheral nervous system neuron A motor neuron that is capable of directly inducing muscle contraction. http://purl.obolibrary.org/obo/PLANA_0000550 interneuron http://purl.obolibrary.org/obo/PLANA_0000099 neuron Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions. http://purl.obolibrary.org/obo/PLANA_0000552 sensory neuron http://purl.obolibrary.org/obo/PLANA_0000545 afferent neuron Any neuron having a sensory function; an afferent neuron conveying sensory impulses. http://purl.obolibrary.org/obo/PLANA_0000553 motor neuron http://purl.obolibrary.org/obo/PLANA_0000548 efferent neuron An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement. http://purl.obolibrary.org/obo/PLANA_0000556 neurosecretory neuron http://purl.obolibrary.org/obo/PLANA_0000105 secretory cell Neuronal cells which synthesize, store and release neurohormones. http://purl.obolibrary.org/obo/PLANA_0000558 sympathetic neuron http://purl.obolibrary.org/obo/PLANA_0000099 neuron Sympathetic neurons are part of the sympathetic nervous system and are primarily adrenergic producing the neurotransmitter noradrenalin along with other neuropeptides. http://purl.obolibrary.org/obo/PLANA_0000559 unipolar neuron http://purl.obolibrary.org/obo/PLANA_0000552 sensory neuron Neuron with one neurite that extends from the cell body. http://purl.obolibrary.org/obo/PLANA_0000560 multipolar neuron http://purl.obolibrary.org/obo/PLANA_0000099 neuron Neuron with an axon and two or more dendrites. http://purl.obolibrary.org/obo/PLANA_0000561 neuron associated cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/PLANA_0000119 terminally differentiated cell Cells that are in close proximity to neurons. http://purl.obolibrary.org/obo/PLANA_0000562 central nervous system neuron http://purl.obolibrary.org/obo/PLANA_0000099 neuron Any neuron that is part of a central nervous system. http://purl.obolibrary.org/obo/PLANA_0000564 peripheral nervous system neuron http://purl.obolibrary.org/obo/PLANA_0000099 neuron Any neuron that is part of a peripheral nervous system. http://purl.obolibrary.org/obo/PLANA_0000565 autonomic neuron http://purl.obolibrary.org/obo/PLANA_0000564 peripheral nervous system neuron A neruon whose cell body is within an autonomic ganglion. http://purl.obolibrary.org/obo/PLANA_0000566 enteric neuron http://purl.obolibrary.org/obo/PLANA_0000565 autonomic neuron A neruon whose cell body is within an autonomic ganglion. http://purl.obolibrary.org/obo/PLANA_0001005 basal lamina of epithelium http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure Acellular anatomical structure that consists of a thin sheet of fibrous proteins that underlie and support the cells of an epithelium. It separates the cells of an epithelium from any underlying tissue. http://purl.obolibrary.org/obo/PLANA_0004503 adult hermaphrodite http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A fully formed, sexually mature organism that reproduces through cross-fertilization. http://purl.obolibrary.org/obo/PLANA_0004504 asexual adult http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage Asexually reproducing Schmidtea mediterranea exist as constitutive adults, undergoing successive cycles of fission and whole animal regeneration. Asexual Schmidtea mediterranea contain primordial germ cells, but do not possess a reproductive system. http://purl.obolibrary.org/obo/PLANA_0004506 testis somatic gonadal cell http://purl.obolibrary.org/obo/PLANA_0002096 somatic gonadal cell dmd-1+ expressing somatic cells within the testis that promote male GSC maintenance. dmd-1+, ophis-1+ somatic gonadal cells ensheath germ cells via long cytoplasmic processes and promote differentiation. http://purl.obolibrary.org/obo/PLANA_0004507 ovarian somatic gonadal cell http://purl.obolibrary.org/obo/PLANA_0000119 terminally differentiated cell ophis+ somatic cells (gh4-, nanos-) in the ovary that may provide trophic support to female germline stem cells and differentiating oogonia. http://purl.obolibrary.org/obo/PLANA_0007503 sagittal plane of the whole animal http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Anatomical plane which divides the body into right and left parts. This plane passes through the midline at the midline but does not always the midline. http://purl.obolibrary.org/obo/PLANA_0007509 plasma membrane http://purl.obolibrary.org/obo/PLANA_0000520 membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. http://purl.obolibrary.org/obo/PLANA_0007511 extracellular organelle http://purl.obolibrary.org/obo/PLANA_0000525 organelle Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi. http://purl.obolibrary.org/obo/PLANA_0007512 mitochondrion http://purl.obolibrary.org/obo/PLANA_0000527 intracellular membrane-bounded organelle A spherical to rod shaped organelle that generates the majority of a cell's supply of ATP via cellular respiration. Mitochondria have their own genome and consist of outer and inner membranes, the latter folds inward to form cristae. This folding increases the surface area of the membrane and thus increases the space available to produce ATP. The inner and outer membranes are separated by an intermembrane space, and the inner membrane encloses the matrix. http://purl.obolibrary.org/obo/PLANA_0007513 endoplasmic reticulum http://purl.obolibrary.org/obo/PLANA_0000527 intracellular membrane-bounded organelle Network of interconnected, flattened, and/or tubular membrane, known as cisternae. This membrane is contiguous with the outer nuclear membrane. The endoplasmic reticulum is involved in both protein and lipid synthesis. http://purl.obolibrary.org/obo/PLANA_0007514 rough endoplasmic reticulum http://purl.obolibrary.org/obo/PLANA_0007513 endoplasmic reticulum Network of interconnected, flattened, and/or tubular membrane, known as cisternae. This membrane is contiguous with the outer nuclear membrane. The endoplasmic reticulum is involved in both protein and lipid synthesis. http://purl.obolibrary.org/obo/PLANA_0007515 smooth endoplasmic reticulum http://purl.obolibrary.org/obo/PLANA_0007513 endoplasmic reticulum Endoplamic reticulum that does not contain ribosomes, which synthesizes lipids, phospholipids, and steroids. http://purl.obolibrary.org/obo/PLANA_0007516 nuclear pore http://purl.obolibrary.org/obo/PLANA_0002079 pore Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined. http://purl.obolibrary.org/obo/PLANA_0007518 lysosome http://purl.obolibrary.org/obo/PLANA_0000527 intracellular membrane-bounded organelle The digestive component of the cell. They are homogenous, dense, membrane bound organelles filled with acid hydrolases which break down polymers. http://purl.obolibrary.org/obo/PLANA_0007519 anterior-posterior axis of the whole animal http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Axis that runs along the long axis of the animal from anterior (head) to posterior (tail). It is perpendicular to the dorsoventral axis and as such, it splits dorsal and ventral regions of the animal to either side. http://purl.obolibrary.org/obo/PLANA_0007520 dorsal-ventral axis of the whole animal http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Axis that runs along the short axis of the animal, perpendicular to the anteroposterior axis, running from the dorsal (back) side of the animal to the ventral (belly) side of the animal. This axis splits anterior and posterior regions of the animal to either side. http://purl.obolibrary.org/obo/PLANA_0007521 left-right axis of the whole animal http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Axis perpendicular to both the anteroposterior and dorsoventral axis that runs from the left side of the animal, through the medial region (center) and out to the right side. http://purl.obolibrary.org/obo/PLANA_0007522 medial-lateral axis of the whole animal http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Axis that runs from the center of the body, starting at the anteroposterior axis and out to the lateral (left, right, dorsal or ventral) surface of the animal. http://purl.obolibrary.org/obo/PLANA_0007523 proximal-distal axis of the whole animal http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Axis that starts at the distal part of an appendage, closest to the body, and runs to the proximal part of an appendage, farthest from the body. http://purl.obolibrary.org/obo/PLANA_0007524 anterior pole http://purl.obolibrary.org/obo/PLANA_0000102 anatomical region Distinct anterior cluster of muscle cells located at the midline which express notum, follistatin, zic-1, and foxD. http://purl.obolibrary.org/obo/PLANA_0007525 posterior pole http://purl.obolibrary.org/obo/PLANA_0000102 anatomical region Distinct posterior cluster of muscle cells located at the midline which express wnt1. http://purl.obolibrary.org/obo/PLANA_0007528 glial cell http://purl.obolibrary.org/obo/BFO_0000040 material entity A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu, guide neuronal migration during development, and exchange metabolites with neurons. http://purl.obolibrary.org/obo/PLANA_0007529 ganglion http://purl.obolibrary.org/obo/PLANA_0000113 tissue A biological tissue mass of nerve cell bodies. http://purl.obolibrary.org/obo/PLANA_0007534 pharynx inner epithelium http://purl.obolibrary.org/obo/PLANA_0002023 ciliated epithelium Heavily ciliated epidermal cells covering the inner surface of the pharynx shaft. http://purl.obolibrary.org/obo/PLANA_0007535 pharynx circular muscle cell http://purl.obolibrary.org/obo/PLANA_0000101 muscle cell Pharynx muscle fibers running circumferentially about the pharynx. http://purl.obolibrary.org/obo/PLANP_0000542 abnormal whole organism http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of whole organism. http://purl.obolibrary.org/obo/PLANP_0000543 abnormal regeneration http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of regeneration. http://purl.obolibrary.org/obo/PLANP_0000544 abnormal Hyman vesicle http://purl.obolibrary.org/obo/PLANP_0000682 abnormal intracellular granule Abnormality of Hyman vesicle. http://purl.obolibrary.org/obo/PLANP_0000545 abnormal anterior region http://purl.obolibrary.org/obo/PLANP_0000542 abnormal whole organism Abnormality of anterior region of the whole animal. http://purl.obolibrary.org/obo/PLANP_0000546 abnormal dorsal region http://purl.obolibrary.org/obo/PLANP_0000548 abnormal ventral region Abnormality of dorsal region of the whole animal. http://purl.obolibrary.org/obo/PLANP_0000547 abnormal posterior region http://purl.obolibrary.org/obo/PLANP_0000542 abnormal whole organism Abnormality of posterior compartment of the whole animal. http://purl.obolibrary.org/obo/PLANP_0000548 abnormal ventral region http://purl.obolibrary.org/obo/PLANP_0000542 abnormal whole organism Abnormality of ventral region of the whole animal. http://purl.obolibrary.org/obo/PLANP_0000549 abnormal heterochromatin http://purl.obolibrary.org/obo/PLANP_0000119 abnormal chromatin Abnormality of heterochromatin. http://purl.obolibrary.org/obo/PLANP_0000550 abnormal adenal rhabdite http://purl.obolibrary.org/obo/PLANP_0000078 abnormal rhabdite Abnormality of adenal rhabdite. http://purl.obolibrary.org/obo/PLANP_0000551 abnormal adherens junction http://purl.obolibrary.org/obo/PLANP_0000420 abnormal cell junction Abnormality of adherens junction. http://purl.obolibrary.org/obo/PLANP_0000552 abnormal adhesive papilla http://purl.obolibrary.org/obo/PLANP_0000366 abnormal cell projection Abnormality of adhesive papilla. http://purl.obolibrary.org/obo/PLANP_0000553 abnormal amputation http://purl.obolibrary.org/obo/PLANP_0000576 abnormal cut Abnormality of amputation. http://purl.obolibrary.org/obo/PLANP_0000554 abnormal anterior gut branch http://purl.obolibrary.org/obo/PLANP_0000666 abnormal gut branch Abnormality of anterior gut branch. http://purl.obolibrary.org/obo/PLANP_0000555 abnormal anterior tip http://purl.obolibrary.org/obo/PLANP_0000261 abnormal anatomical region Abnormality of anterior tip. http://purl.obolibrary.org/obo/PLANP_0000556 abnormal antrum http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of antrum. http://purl.obolibrary.org/obo/PLANP_0000557 abnormal auricle http://purl.obolibrary.org/obo/PLANP_0000365 abnormal peripheral nervous system Abnormality of auricle. http://purl.obolibrary.org/obo/PLANP_0000558 abnormal axon http://purl.obolibrary.org/obo/PLANP_0000611 abnormal neurite Abnormality of axon. http://purl.obolibrary.org/obo/PLANP_0000559 abnormal axoneme http://purl.obolibrary.org/obo/PLANP_0000067 abnormal intracellular non-membrane-bounded organelle Abnormality of axoneme. http://purl.obolibrary.org/obo/PLANP_0000560 abnormal basal body http://purl.obolibrary.org/obo/PLANP_0000067 abnormal intracellular non-membrane-bounded organelle Abnormality of basal body. http://purl.obolibrary.org/obo/PLANP_0000561 abnormal brain visual center http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of brain visual center. http://purl.obolibrary.org/obo/PLANP_0000562 abnormal bulbar cavity http://purl.obolibrary.org/obo/PLANP_0000136 abnormal seminal vesicle Abnormality of bulbar cavity. http://purl.obolibrary.org/obo/PLANP_0000563 abnormal Category 1 cell http://purl.obolibrary.org/obo/PLANP_0000704 abnormal parenchymal cell Abnormality of Category 1 cell. http://purl.obolibrary.org/obo/PLANP_0000564 abnormal cell body http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of cell body. http://purl.obolibrary.org/obo/PLANP_0000565 abnormal cephalic ganglia lobe http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of cephalic ganglia lobe. http://purl.obolibrary.org/obo/PLANP_0000566 abnormal cephalic ganglia neuron http://purl.obolibrary.org/obo/PLANP_0000149 abnormal cephalic ganglia Abnormality of cephalic ganglia neuron. http://purl.obolibrary.org/obo/PLANP_0000567 abnormal chemical amputation http://purl.obolibrary.org/obo/PLANP_0000657 abnormal wound Abnormality of chemical amputation. http://purl.obolibrary.org/obo/PLANP_0000568 abnormal chemical pharynx amputation http://purl.obolibrary.org/obo/PLANP_0000567 abnormal chemical amputation Abnormality of chemical pharynx amputation. http://purl.obolibrary.org/obo/PLANP_0000569 abnormal chemosensory neuron http://purl.obolibrary.org/obo/PLANP_0000416 abnormal sensory neuron Abnormality of chemosensory neuron. http://purl.obolibrary.org/obo/PLANP_0000570 abnormal chromatoid body http://purl.obolibrary.org/obo/PLANP_0000192 abnormal non-membrane-bounded organelle Abnormality of chromatoid body. http://purl.obolibrary.org/obo/PLANP_0000571 abnormal chromosome http://purl.obolibrary.org/obo/PLANP_0000192 abnormal non-membrane-bounded organelle Abnormality of chromosome. http://purl.obolibrary.org/obo/PLANP_0000572 abnormal chromosome arm http://purl.obolibrary.org/obo/PLANP_0000571 abnormal chromosome Abnormality of chromosome arm. http://purl.obolibrary.org/obo/PLANP_0000573 abnormal ciliated epithelium http://purl.obolibrary.org/obo/PLANP_0000665 abnormal epithelium Abnormality of ciliated epithelium. http://purl.obolibrary.org/obo/PLANP_0000574 abnormal cilium http://purl.obolibrary.org/obo/PLANP_0000366 abnormal cell projection Abnormality of cilium. http://purl.obolibrary.org/obo/PLANP_0000575 abnormal commissure http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of commissure. http://purl.obolibrary.org/obo/PLANP_0000576 abnormal cut http://purl.obolibrary.org/obo/PLANP_0000648 abnormal surgical wound Abnormality of cut. http://purl.obolibrary.org/obo/PLANP_0000577 abnormal dendrite http://purl.obolibrary.org/obo/PLANP_0000611 abnormal neurite Abnormality of dendrite. http://purl.obolibrary.org/obo/PLANP_0000578 abnormal dorsal-ventral muscle cell http://purl.obolibrary.org/obo/PLANP_0000256 abnormal parenchymal musculature Abnormality of dorsal-ventral muscle cell. http://purl.obolibrary.org/obo/PLANP_0000579 abnormal early female germ cell http://purl.obolibrary.org/obo/PLANP_0000437 abnormal female germ cell Abnormality of early female germ cell. http://purl.obolibrary.org/obo/PLANP_0000580 abnormal early male germ cell http://purl.obolibrary.org/obo/PLANP_0000280 abnormal testis Abnormality of early male germ cell. http://purl.obolibrary.org/obo/PLANP_0000581 abnormal embryonic gut http://purl.obolibrary.org/obo/PLANP_0000090 abnormal embryonic digestive system Abnormality of embryonic gut. http://purl.obolibrary.org/obo/PLANP_0000582 abnormal epidermal cell http://purl.obolibrary.org/obo/PLANP_0000310 abnormal epithelial cell Abnormality of epidermal cell. http://purl.obolibrary.org/obo/PLANP_0000583 abnormal epidermal rhabdite http://purl.obolibrary.org/obo/PLANP_0000078 abnormal rhabdite Abnormality of epidermal rhabdite. http://purl.obolibrary.org/obo/PLANP_0000584 abnormal ER membrane http://purl.obolibrary.org/obo/PLANP_0000313 abnormal endoplasmic reticulum Abnormality of ER membrane. http://purl.obolibrary.org/obo/PLANP_0000585 abnormal eumelanin http://purl.obolibrary.org/obo/PLANP_0000608 abnormal melanosome Abnormality of eumelanin. http://purl.obolibrary.org/obo/PLANP_0000586 abnormal excretory cell http://purl.obolibrary.org/obo/PLANP_0000268 abnormal terminally differentiated cell Abnormality of excretory cell. http://purl.obolibrary.org/obo/PLANP_0000587 abnormal extracellular matrix http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of extracellular matrix. http://purl.obolibrary.org/obo/PLANP_0000588 abnormal extracellular space http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of extracellular space. http://purl.obolibrary.org/obo/PLANP_0000589 abnormal fission http://purl.obolibrary.org/obo/PLANP_0000657 abnormal wound Abnormality of fission. http://purl.obolibrary.org/obo/PLANP_0000590 abnormal flagellum http://purl.obolibrary.org/obo/PLANP_0000366 abnormal cell projection Abnormality of flagellum. http://purl.obolibrary.org/obo/PLANP_0000591 abnormal gap junction http://purl.obolibrary.org/obo/PLANP_0000265 abnormal cell-cell junction Abnormality of gap junction. http://purl.obolibrary.org/obo/PLANP_0000592 abnormal genital atrium http://purl.obolibrary.org/obo/PLANP_0000353 abnormal reproductive system Abnormality of genital atrium. http://purl.obolibrary.org/obo/PLANP_0000593 abnormal germ cell cyst http://purl.obolibrary.org/obo/PLANP_0000161 abnormal gonad Abnormality of germ cell cyst. http://purl.obolibrary.org/obo/PLANP_0000594 abnormal germline stem cell http://purl.obolibrary.org/obo/PLANP_0000283 abnormal stem cell Abnormality of germline stem cell. http://purl.obolibrary.org/obo/PLANP_0000595 abnormal glycogen granule http://purl.obolibrary.org/obo/PLANP_0000682 abnormal intracellular granule Abnormality of glycogen granule. http://purl.obolibrary.org/obo/PLANP_0000596 abnormal incision http://purl.obolibrary.org/obo/PLANP_0000576 abnormal cut Abnormality of incision. http://purl.obolibrary.org/obo/PLANP_0000597 abnormal pharynx inner epidermal cell http://purl.obolibrary.org/obo/PLANP_0000150 abnormal ciliated epithelial cell Abnormality of pharynx inner epidermal cell. http://purl.obolibrary.org/obo/PLANP_0000598 abnormal inner zone of gland cells http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of inner zone of gland cells. http://purl.obolibrary.org/obo/PLANP_0000599 abnormal intercellular junction http://purl.obolibrary.org/obo/PLANP_0000265 abnormal cell-cell junction Abnormality of intercellular junction. http://purl.obolibrary.org/obo/PLANP_0000600 abnormal linear amputation http://purl.obolibrary.org/obo/PLANP_0000553 abnormal amputation Abnormality of linear amputation. http://purl.obolibrary.org/obo/PLANP_0000601 abnormal linear incision http://purl.obolibrary.org/obo/PLANP_0000596 abnormal incision Abnormality of linear incision. http://purl.obolibrary.org/obo/PLANP_0000602 abnormal lipid droplet http://purl.obolibrary.org/obo/PLANP_0000067 abnormal intracellular non-membrane-bounded organelle Abnormality of lipid droplet. http://purl.obolibrary.org/obo/PLANP_0000603 abnormal lumen http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of lumen. http://purl.obolibrary.org/obo/PLANP_0000604 abnormal marginal adhesive zone http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of marginal adhesive zone. http://purl.obolibrary.org/obo/PLANP_0000605 abnormal mechanosensory neuron http://purl.obolibrary.org/obo/PLANP_0000416 abnormal sensory neuron Abnormality of mechanosensory neuron. http://purl.obolibrary.org/obo/PLANP_0000606 abnormal medial muscle cell http://purl.obolibrary.org/obo/PLANP_0000256 abnormal parenchymal musculature Abnormality of medial muscle cell. http://purl.obolibrary.org/obo/PLANP_0000607 abnormal meiotic germ cell http://purl.obolibrary.org/obo/PLANP_0000288 abnormal germ cell Abnormality of meiotic germ cell. http://purl.obolibrary.org/obo/PLANP_0000608 abnormal melanosome http://purl.obolibrary.org/obo/PLANP_0000398 abnormal intracellular membrane-bounded organelle Abnormality of melanosome. http://purl.obolibrary.org/obo/PLANP_0000609 abnormal mucus http://purl.obolibrary.org/obo/PLANP_0000384 abnormal secretory system Abnormality of mucus. http://purl.obolibrary.org/obo/PLANP_0000610 abnormal nephridiopore http://purl.obolibrary.org/obo/PLANP_0000230 abnormal flame cell Abnormality of nephridiopore. http://purl.obolibrary.org/obo/PLANP_0000611 abnormal neurite http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron Abnormality of neurite. http://purl.obolibrary.org/obo/PLANP_0000612 abnormal neuropeptidergic neuron http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron Abnormality of neuropeptidergic neuron. http://purl.obolibrary.org/obo/PLANP_0000613 abnormal non-ciliated epidermis http://purl.obolibrary.org/obo/PLANP_0000427 abnormal epidermis Abnormality of non-ciliated epidermis. http://purl.obolibrary.org/obo/PLANP_0000614 abnormal nuclear envelope http://purl.obolibrary.org/obo/PLANP_0000229 abnormal membrane Abnormality of nuclear envelope. http://purl.obolibrary.org/obo/PLANP_0000615 abnormal nuclear inner membrane http://purl.obolibrary.org/obo/PLANP_0000388 abnormal membrane part Abnormality of nuclear inner membrane. http://purl.obolibrary.org/obo/PLANP_0000616 abnormal nuclear lumen http://purl.obolibrary.org/obo/PLANP_0000170 abnormal nuclear part Abnormality of nuclear lumen. http://purl.obolibrary.org/obo/PLANP_0000617 abnormal nuclear outer membrane http://purl.obolibrary.org/obo/PLANP_0000388 abnormal membrane part Abnormality of nuclear outer membrane. http://purl.obolibrary.org/obo/PLANP_0000618 abnormal nuclear periphery http://purl.obolibrary.org/obo/PLANP_0000170 abnormal nuclear part Abnormality of nuclear periphery. http://purl.obolibrary.org/obo/PLANP_0000619 abnormal ommochrome pigment cell http://purl.obolibrary.org/obo/PLANP_0000624 abnormal pigment cell Abnormality of ommochrome pigment cell. http://purl.obolibrary.org/obo/PLANP_0000620 abnormal optic nerve http://purl.obolibrary.org/obo/PLANP_0000456 abnormal nerve Abnormality of optic nerve. http://purl.obolibrary.org/obo/PLANP_0000621 abnormal pharynx outer epidermal cell http://purl.obolibrary.org/obo/PLANP_0000150 abnormal ciliated epithelial cell Abnormality of pharynx outer epidermal cell. http://purl.obolibrary.org/obo/PLANP_0000622 abnormal phagocytic cell http://purl.obolibrary.org/obo/PLANP_0000268 abnormal terminally differentiated cell Abnormality of phagocytic cell. http://purl.obolibrary.org/obo/PLANP_0000623 abnormal pharynx tip http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of pharynx tip. http://purl.obolibrary.org/obo/PLANP_0000624 abnormal pigment cell http://purl.obolibrary.org/obo/PLANP_0000268 abnormal terminally differentiated cell Abnormality of pigment cell. http://purl.obolibrary.org/obo/PLANP_0000625 abnormal pigment granule http://purl.obolibrary.org/obo/PLANP_0000131 abnormal membrane-bounded organelle Abnormality of pigment granule. http://purl.obolibrary.org/obo/PLANP_0000626 abnormal plug amputation http://purl.obolibrary.org/obo/PLANP_0000553 abnormal amputation Abnormality of plug amputation. http://purl.obolibrary.org/obo/PLANP_0000627 abnormal point incision http://purl.obolibrary.org/obo/PLANP_0000596 abnormal incision Abnormality of point incision. http://purl.obolibrary.org/obo/PLANP_0000628 abnormal pore http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of pore. http://purl.obolibrary.org/obo/PLANP_0000629 abnormal post-meiotic germ cell http://purl.obolibrary.org/obo/PLANP_0000288 abnormal germ cell Abnormality of post-meiotic germ cell. http://purl.obolibrary.org/obo/PLANP_0000630 abnormal postsynaptic cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of postsynaptic cell. http://purl.obolibrary.org/obo/PLANP_0000631 abnormal premeiotic germ cell http://purl.obolibrary.org/obo/PLANP_0000288 abnormal germ cell Abnormality of premeiotic germ cell. http://purl.obolibrary.org/obo/PLANP_0000632 abnormal presynaptic cell http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron Abnormality of presynaptic cell. http://purl.obolibrary.org/obo/PLANP_0000633 abnormal presynaptic terminal http://purl.obolibrary.org/obo/PLANP_0000632 abnormal presynaptic cell Abnormality of presynaptic terminal. http://purl.obolibrary.org/obo/PLANP_0000634 abnormal presynaptic vesicle http://purl.obolibrary.org/obo/PLANP_0000131 abnormal membrane-bounded organelle Abnormality of presynaptic vesicle. http://purl.obolibrary.org/obo/PLANP_0000635 abnormal primary gut branch http://purl.obolibrary.org/obo/PLANP_0000666 abnormal gut branch Abnormality of primary gut branch. http://purl.obolibrary.org/obo/PLANP_0000636 abnormal primitive gut http://purl.obolibrary.org/obo/PLANP_0000090 abnormal embryonic digestive system Abnormality of primitive gut. http://purl.obolibrary.org/obo/PLANP_0000637 abnormal quarternary gut branch http://purl.obolibrary.org/obo/PLANP_0000666 abnormal gut branch Abnormality of quarternary gut branch. http://purl.obolibrary.org/obo/PLANP_0000638 abnormal reproductive organ http://purl.obolibrary.org/obo/PLANP_0000353 abnormal reproductive system Abnormality of reproductive organ. http://purl.obolibrary.org/obo/PLANP_0000639 abnormal reproductive structure http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of reproductive structure. http://purl.obolibrary.org/obo/PLANP_0000640 abnormal rhabdome http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of rhabdome. http://purl.obolibrary.org/obo/PLANP_0000641 abnormal rhabdomere http://purl.obolibrary.org/obo/PLANP_0000366 abnormal cell projection Abnormality of rhabdomere. http://purl.obolibrary.org/obo/PLANP_0000642 abnormal secretory duct http://purl.obolibrary.org/obo/PLANP_0000384 abnormal secretory system Abnormality of secretory duct. http://purl.obolibrary.org/obo/PLANP_0000643 abnormal secretory granule http://purl.obolibrary.org/obo/PLANP_0000331 abnormal secretory cell Abnormality of secretory granule. http://purl.obolibrary.org/obo/PLANP_0000644 abnormal somatic cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of somatic cell. http://purl.obolibrary.org/obo/PLANP_0000645 abnormal somatic gonadal cell http://purl.obolibrary.org/obo/PLANP_0000268 abnormal terminally differentiated cell Abnormality of somatic gonadal cell. http://purl.obolibrary.org/obo/PLANP_0000646 abnormal specialized neoblast http://purl.obolibrary.org/obo/PLANP_0000029 abnormal neoblast Abnormality of specialized neoblast. http://purl.obolibrary.org/obo/PLANP_0000647 abnormal stalk http://purl.obolibrary.org/obo/PLANP_0000329 abnormal egg capsule Abnormality of stalk. http://purl.obolibrary.org/obo/PLANP_0000648 abnormal surgical wound http://purl.obolibrary.org/obo/PLANP_0000657 abnormal wound Abnormality of surgical wound. http://purl.obolibrary.org/obo/PLANP_0000649 abnormal synapse http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron Abnormality of synapse. http://purl.obolibrary.org/obo/PLANP_0000650 abnormal synaptic cleft http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron Abnormality of synaptic cleft. http://purl.obolibrary.org/obo/PLANP_0000651 abnormal synaptic vesicle http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron Abnormality of synaptic vesicle. http://purl.obolibrary.org/obo/PLANP_0000652 abnormal synaptonemal complex http://purl.obolibrary.org/obo/PLANP_0000670 abnormal chromosomal:structural:element Abnormality of synaptonemal complex. http://purl.obolibrary.org/obo/PLANP_0000653 abnormal tail tip http://purl.obolibrary.org/obo/PLANP_0000261 abnormal anatomical region Abnormality of tail tip. http://purl.obolibrary.org/obo/PLANP_0000654 abnormal telomere http://purl.obolibrary.org/obo/PLANP_0000668 abnormal chromosome:part Abnormality of telomere. http://purl.obolibrary.org/obo/PLANP_0000655 abnormal tight junction http://purl.obolibrary.org/obo/PLANP_0000265 abnormal cell-cell junction Abnormality of septate junction. http://purl.obolibrary.org/obo/PLANP_0000656 abnormal wedge amputation http://purl.obolibrary.org/obo/PLANP_0000553 abnormal amputation Abnormality of wedge amputation. http://purl.obolibrary.org/obo/PLANP_0000657 abnormal wound http://purl.obolibrary.org/obo/PLANP_0000669 abnormal perturbation Abnormality of wound. http://purl.obolibrary.org/obo/PLANP_0000658 abnormal X1 cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of X1 cell. http://purl.obolibrary.org/obo/PLANP_0000659 abnormal X1(FS) cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of X1(FS) cell. http://purl.obolibrary.org/obo/PLANP_0000660 abnormal X2 cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of X2 cell. http://purl.obolibrary.org/obo/PLANP_0000661 abnormal Xins cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of Xins cell. http://purl.obolibrary.org/obo/PLANP_0000662 abnormal post-pharyngeal region http://purl.obolibrary.org/obo/PLANP_0000261 abnormal anatomical region Abnormality of post-pharyngeal region. http://purl.obolibrary.org/obo/PLANP_0000663 abnormal post-blastema region http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of post-blastema region. http://purl.obolibrary.org/obo/PLANP_0000664 abnormal fission fragment http://purl.obolibrary.org/obo/PLANP_0000673 abnormal fragment Abnormality of fission fragment. http://purl.obolibrary.org/obo/PLANP_0000665 abnormal epithelium http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of epithelium. http://purl.obolibrary.org/obo/PLANP_0000666 abnormal gut branch http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of gut branch. http://purl.obolibrary.org/obo/PLANP_0000667 abnormal extraembryonic organ http://purl.obolibrary.org/obo/PLANP_0000289 abnormal embryo Abnormality of extraembryonic organ. http://purl.obolibrary.org/obo/PLANP_0000668 abnormal chromosome:part http://purl.obolibrary.org/obo/PLANP_0000571 abnormal chromosome Abnormality of chromosome_part. http://purl.obolibrary.org/obo/PLANP_0000669 abnormal perturbation http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of perturbation. http://purl.obolibrary.org/obo/PLANP_0000670 abnormal chromosomal:structural:element http://purl.obolibrary.org/obo/PLANP_0000668 abnormal chromosome:part Abnormality of chromosomal_structural_element. http://purl.obolibrary.org/obo/PLANP_0000671 abnormal thick fragment http://purl.obolibrary.org/obo/PLANP_0000786 abnormal longitudinal fragment Abnormality of thick fragment. http://purl.obolibrary.org/obo/PLANP_0000672 abnormal thin fragment http://purl.obolibrary.org/obo/PLANP_0000786 abnormal longitudinal fragment Abnormality of thin fragment. http://purl.obolibrary.org/obo/PLANP_0000673 abnormal fragment http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of fragment. http://purl.obolibrary.org/obo/PLANP_0000674 abnormal longitudinal region http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of longitudinal region. http://purl.obolibrary.org/obo/PLANP_0000675 abnormal chemical wound http://purl.obolibrary.org/obo/PLANP_0000657 abnormal wound Abnormality of chemical wound. http://purl.obolibrary.org/obo/PLANP_0000676 abnormal plug wound http://purl.obolibrary.org/obo/PLANP_0000657 abnormal wound Abnormality of plug wound. http://purl.obolibrary.org/obo/PLANP_0000677 abnormal wedge wound http://purl.obolibrary.org/obo/PLANP_0000657 abnormal wound Abnormality of wedge wound. http://purl.obolibrary.org/obo/PLANP_0000678 abnormal regenerating fragment http://purl.obolibrary.org/obo/PLANP_0000673 abnormal fragment Abnormality of regenerating fragment. http://purl.obolibrary.org/obo/PLANP_0000679 abnormal sagittal orientation http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of sagittal orientation. http://purl.obolibrary.org/obo/PLANP_0000680 abnormal parasagittal orientation http://purl.obolibrary.org/obo/PLANP_0000679 abnormal sagittal orientation Abnormality of parasagittal orientation. http://purl.obolibrary.org/obo/PLANP_0000681 abnormal syncytium http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of syncytium. http://purl.obolibrary.org/obo/PLANP_0000682 abnormal intracellular granule http://purl.obolibrary.org/obo/PLANP_0000067 abnormal intracellular non-membrane-bounded organelle Abnormality of intracellular granule. http://purl.obolibrary.org/obo/PLANP_0000683 abnormal FACS sorted cell population http://purl.obolibrary.org/obo/PLANP_0000684 abnormal derived cell population Abnormality of FACS sorted cell population. http://purl.obolibrary.org/obo/PLANP_0000684 abnormal derived cell population http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of derived cell population. http://purl.obolibrary.org/obo/PLANP_0000685 abnormal pharynx pouch epithelium http://purl.obolibrary.org/obo/PLANP_0000185 abnormal pharynx pouch Abnormality of pharynx pouch epithelium. http://purl.obolibrary.org/obo/PLANP_0000686 abnormal sperm duct epithelial surface http://purl.obolibrary.org/obo/PLANP_0000105 abnormal sperm duct epithelium Abnormality of sperm duct epithelial surface. http://purl.obolibrary.org/obo/PLANP_0000687 abnormal parenchyma http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of parenchyma. http://purl.obolibrary.org/obo/PLANP_0000688 abnormal testis cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of testis cell. http://purl.obolibrary.org/obo/PLANP_0000689 abnormal ventral epidermis cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of ventral epidermis cell. http://purl.obolibrary.org/obo/PLANP_0000690 abnormal visual system cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of visual system cell. http://purl.obolibrary.org/obo/PLANP_0000691 abnormal eye cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of eye cell. http://purl.obolibrary.org/obo/PLANP_0000692 abnormal enteric muscle cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of enteric muscle cell. http://purl.obolibrary.org/obo/PLANP_0000693 abnormal dorsal epidermis cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of dorsal epidermis cell. http://purl.obolibrary.org/obo/PLANP_0000694 abnormal adhesion gland cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of adhesion gland cell. http://purl.obolibrary.org/obo/PLANP_0000695 abnormal body wall muscle cell http://purl.obolibrary.org/obo/PLANP_0000392 abnormal body wall musculature Abnormality of body wall muscle cell. http://purl.obolibrary.org/obo/PLANP_0000696 abnormal gastrodermal cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of gastrodermal cell. http://purl.obolibrary.org/obo/PLANP_0000697 abnormal anterior pole cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of anterior pole cell. http://purl.obolibrary.org/obo/PLANP_0000698 abnormal pharynx neuron http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron Abnormality of pharynx neuron. http://purl.obolibrary.org/obo/PLANP_0000699 abnormal pharynx epithelial cell http://purl.obolibrary.org/obo/PLANP_0000310 abnormal epithelial cell Abnormality of pharynx epithelial cell. http://purl.obolibrary.org/obo/PLANP_0000700 abnormal pharynx muscle cell http://purl.obolibrary.org/obo/PLANP_0000091 abnormal muscle cell Abnormality of pharynx muscle cell. http://purl.obolibrary.org/obo/PLANP_0000701 abnormal pharynx pouch epithelial cell http://purl.obolibrary.org/obo/PLANP_0000310 abnormal epithelial cell Abnormality of pharynx pouch epithelial cell. http://purl.obolibrary.org/obo/PLANP_0000702 abnormal melanin pigment granule http://purl.obolibrary.org/obo/PLANP_0000625 abnormal pigment granule Abnormality of melanin pigment granule. http://purl.obolibrary.org/obo/PLANP_0000703 abnormal ommochrome pigment granule http://purl.obolibrary.org/obo/PLANP_0000625 abnormal pigment granule Abnormality of ommochrome pigment granule. http://purl.obolibrary.org/obo/PLANP_0000704 abnormal parenchymal cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of parenchymal cell. http://purl.obolibrary.org/obo/PLANP_0000705 abnormal G1 phase neoblast http://purl.obolibrary.org/obo/PLANP_0000029 abnormal neoblast Abnormality of G1 phase neoblast. http://purl.obolibrary.org/obo/PLANP_0000706 abnormal S phase neoblast http://purl.obolibrary.org/obo/PLANP_0000029 abnormal neoblast Abnormality of S phase neoblast. http://purl.obolibrary.org/obo/PLANP_0000707 abnormal G2 phase neoblast http://purl.obolibrary.org/obo/PLANP_0000029 abnormal neoblast Abnormality of G2 phase neoblast. http://purl.obolibrary.org/obo/PLANP_0000708 abnormal prophase neoblast http://purl.obolibrary.org/obo/PLANP_0000029 abnormal neoblast Abnormality of prophase neoblast. http://purl.obolibrary.org/obo/PLANP_0000709 abnormal metaphase neoblast http://purl.obolibrary.org/obo/PLANP_0000029 abnormal neoblast Abnormality of metaphase neoblast. http://purl.obolibrary.org/obo/PLANP_0000710 abnormal anaphase neoblast http://purl.obolibrary.org/obo/PLANP_0000029 abnormal neoblast Abnormality of anaphase neoblast. http://purl.obolibrary.org/obo/PLANP_0000711 abnormal telophase neoblast http://purl.obolibrary.org/obo/PLANP_0000029 abnormal neoblast Abnormality of telophase neoblast. http://purl.obolibrary.org/obo/PLANP_0000712 abnormal G1 phase spermatogonial stem cell http://purl.obolibrary.org/obo/PLANP_0000250 abnormal spermatogonial stem cell Abnormality of G1 phase spermatogonial stem cell. http://purl.obolibrary.org/obo/PLANP_0000713 abnormal S phase spermatogonial stem cell http://purl.obolibrary.org/obo/PLANP_0000250 abnormal spermatogonial stem cell Abnormality of S phase spermatogonial stem cell. http://purl.obolibrary.org/obo/PLANP_0000714 abnormal G2 phase spermatogonial stem cell http://purl.obolibrary.org/obo/PLANP_0000250 abnormal spermatogonial stem cell Abnormality of G2 phase spermatogonial stem cell. http://purl.obolibrary.org/obo/PLANP_0000715 abnormal prophase spermatogonial stem cell http://purl.obolibrary.org/obo/PLANP_0000250 abnormal spermatogonial stem cell Abnormality of prophase spermatogonial stem cell. http://purl.obolibrary.org/obo/PLANP_0000716 abnormal metaphase spermatogonial stem cell http://purl.obolibrary.org/obo/PLANP_0000250 abnormal spermatogonial stem cell Abnormality of metaphase spermatogonial stem cell. http://purl.obolibrary.org/obo/PLANP_0000717 abnormal anaphase spermatogonial stem cell http://purl.obolibrary.org/obo/PLANP_0000250 abnormal spermatogonial stem cell Abnormality of anaphase spermatogonial stem cell. http://purl.obolibrary.org/obo/PLANP_0000718 abnormal telophase spermatogonial stem cell http://purl.obolibrary.org/obo/PLANP_0000250 abnormal spermatogonial stem cell Abnormality of telophase spermatogonial stem cell. http://purl.obolibrary.org/obo/PLANP_0000719 abnormal G1 phase oogonial stem cell http://purl.obolibrary.org/obo/PLANP_0000399 abnormal oogonial stem cell Abnormality of G1 phase oogonial stem cell. http://purl.obolibrary.org/obo/PLANP_0000720 abnormal S phase oogonial stem cell http://purl.obolibrary.org/obo/PLANP_0000399 abnormal oogonial stem cell Abnormality of S phase oogonial stem cell. http://purl.obolibrary.org/obo/PLANP_0000721 abnormal G2 phase oogonial stem cell http://purl.obolibrary.org/obo/PLANP_0000399 abnormal oogonial stem cell Abnormality of G2 phase oogonial stem cell. http://purl.obolibrary.org/obo/PLANP_0000722 abnormal prophase oogonial stem cell http://purl.obolibrary.org/obo/PLANP_0000399 abnormal oogonial stem cell Abnormality of prophase oogonial stem cell. http://purl.obolibrary.org/obo/PLANP_0000723 abnormal metaphase oogonial stem cell http://purl.obolibrary.org/obo/PLANP_0000399 abnormal oogonial stem cell Abnormality of metaphase oogonial stem cell. http://purl.obolibrary.org/obo/PLANP_0000724 abnormal anaphase oogonial stem cell http://purl.obolibrary.org/obo/PLANP_0000399 abnormal oogonial stem cell Abnormality of anaphase oogonial stem cell. http://purl.obolibrary.org/obo/PLANP_0000725 abnormal telophase oogonial stem cell http://purl.obolibrary.org/obo/PLANP_0000399 abnormal oogonial stem cell Abnormality of telophase oogonial stem cell. http://purl.obolibrary.org/obo/PLANP_0000726 abnormal G1 phase spermatogonium http://purl.obolibrary.org/obo/PLANP_0000132 abnormal spermatogonium Abnormality of G1 phase spermatogonium. http://purl.obolibrary.org/obo/PLANP_0000727 abnormal S phase spermatogonium http://purl.obolibrary.org/obo/PLANP_0000132 abnormal spermatogonium Abnormality of S phase spermatogonium. http://purl.obolibrary.org/obo/PLANP_0000728 abnormal G2 phase spermatogonium http://purl.obolibrary.org/obo/PLANP_0000132 abnormal spermatogonium Abnormality of G2 phase spermatogonium. http://purl.obolibrary.org/obo/PLANP_0000729 abnormal prophase spermatogonium http://purl.obolibrary.org/obo/PLANP_0000132 abnormal spermatogonium Abnormality of prophase spermatogonium. http://purl.obolibrary.org/obo/PLANP_0000730 abnormal metaphase spermatogonia http://purl.obolibrary.org/obo/PLANP_0000132 abnormal spermatogonium Abnormality of metaphase spermatogonia. http://purl.obolibrary.org/obo/PLANP_0000731 abnormal anaphase spermatogonia http://purl.obolibrary.org/obo/PLANP_0000132 abnormal spermatogonium Abnormality of anaphase spermatogonia. http://purl.obolibrary.org/obo/PLANP_0000732 abnormal telophase spermatogonium http://purl.obolibrary.org/obo/PLANP_0000132 abnormal spermatogonium Abnormality of telophase spermatogonium. http://purl.obolibrary.org/obo/PLANP_0000733 abnormal G1 phase oogonial cell http://purl.obolibrary.org/obo/PLANP_0000216 abnormal oogonial cell Abnormality of G1 phase oogonial cell. http://purl.obolibrary.org/obo/PLANP_0000734 abnormal S phase oogonial cell http://purl.obolibrary.org/obo/PLANP_0000216 abnormal oogonial cell Abnormality of S phase oogonial cell. http://purl.obolibrary.org/obo/PLANP_0000735 abnormal G2 phase oogonial cell http://purl.obolibrary.org/obo/PLANP_0000216 abnormal oogonial cell Abnormality of G2 phase oogonial cell. http://purl.obolibrary.org/obo/PLANP_0000736 abnormal prophase oogonial cell http://purl.obolibrary.org/obo/PLANP_0000216 abnormal oogonial cell Abnormality of prophase oogonial cell. http://purl.obolibrary.org/obo/PLANP_0000737 abnormal metaphase oogonial cell http://purl.obolibrary.org/obo/PLANP_0000216 abnormal oogonial cell Abnormality of metaphase oogonial cell. http://purl.obolibrary.org/obo/PLANP_0000738 abnormal anaphase oogonial cell http://purl.obolibrary.org/obo/PLANP_0000216 abnormal oogonial cell Abnormality of anaphase oogonial cell. http://purl.obolibrary.org/obo/PLANP_0000739 abnormal telophase oogonial cell http://purl.obolibrary.org/obo/PLANP_0000216 abnormal oogonial cell Abnormality of telophase oogonial cell. http://purl.obolibrary.org/obo/PLANP_0000740 abnormal G1 phase germ cell cyst http://purl.obolibrary.org/obo/PLANP_0000593 abnormal germ cell cyst Abnormality of G1 phase germ cell cyst. http://purl.obolibrary.org/obo/PLANP_0000741 abnormal S phase germ cell cyst http://purl.obolibrary.org/obo/PLANP_0000593 abnormal germ cell cyst Abnormality of S phase germ cell cyst. http://purl.obolibrary.org/obo/PLANP_0000742 abnormal G2 phase germ cell cyst http://purl.obolibrary.org/obo/PLANP_0000593 abnormal germ cell cyst Abnormality of G2 phase germ cell cyst. http://purl.obolibrary.org/obo/PLANP_0000743 abnormal prophase germ cell cyst http://purl.obolibrary.org/obo/PLANP_0000593 abnormal germ cell cyst Abnormality of prophase germ cell cyst. http://purl.obolibrary.org/obo/PLANP_0000744 abnormal metaphase germ cell cyst http://purl.obolibrary.org/obo/PLANP_0000593 abnormal germ cell cyst Abnormality of metaphase germ cell cyst. http://purl.obolibrary.org/obo/PLANP_0000745 abnormal anaphase germ cell cyst http://purl.obolibrary.org/obo/PLANP_0000593 abnormal germ cell cyst Abnormality of anaphase germ cell cyst. http://purl.obolibrary.org/obo/PLANP_0000746 abnormal telophase germ cell cyst http://purl.obolibrary.org/obo/PLANP_0000593 abnormal germ cell cyst Abnormality of telophase germ cell cyst. http://purl.obolibrary.org/obo/PLANP_0000747 abnormal meiotic S phase spermatocyte http://purl.obolibrary.org/obo/PLANP_0000445 abnormal spermatocyte Abnormality of meiotic S phase spermatocyte. http://purl.obolibrary.org/obo/PLANP_0000748 abnormal meiotic G1 phase spermatocyte http://purl.obolibrary.org/obo/PLANP_0000445 abnormal spermatocyte Abnormality of meiotic G1 phase spermatocyte. http://purl.obolibrary.org/obo/PLANP_0000749 abnormal meiotic G2 phase spermatocyte http://purl.obolibrary.org/obo/PLANP_0000445 abnormal spermatocyte Abnormality of meiotic G2 phase spermatocyte. http://purl.obolibrary.org/obo/PLANP_0000750 abnormal meiotic prophase I spermatocyte http://purl.obolibrary.org/obo/PLANP_0000445 abnormal spermatocyte Abnormality of meiotic prophase I spermatocyte. http://purl.obolibrary.org/obo/PLANP_0000751 abnormal leptotene stage spermatocyte http://purl.obolibrary.org/obo/PLANP_0000445 abnormal spermatocyte Abnormality of leptotene stage spermatocyte. http://purl.obolibrary.org/obo/PLANP_0000752 abnormal zygotene stage spermatocyte http://purl.obolibrary.org/obo/PLANP_0000445 abnormal spermatocyte Abnormality of zygotene stage spermatocyte. http://purl.obolibrary.org/obo/PLANP_0000753 abnormal pachytene stage spermatocyte http://purl.obolibrary.org/obo/PLANP_0000445 abnormal spermatocyte Abnormality of pachytene stage spermatocyte. http://purl.obolibrary.org/obo/PLANP_0000754 abnormal diplotene stage spermatocyte http://purl.obolibrary.org/obo/PLANP_0000445 abnormal spermatocyte Abnormality of diplotene stage spermatocyte. http://purl.obolibrary.org/obo/PLANP_0000755 abnormal diakinesis stage spermatocyte http://purl.obolibrary.org/obo/PLANP_0000445 abnormal spermatocyte Abnormality of diakinesis stage spermatocyte. http://purl.obolibrary.org/obo/PLANP_0000756 abnormal meiotic metaphase 1 stage spermatocyte http://purl.obolibrary.org/obo/PLANP_0000445 abnormal spermatocyte Abnormality of meiotic metaphase 1 stage spermatocyte. http://purl.obolibrary.org/obo/PLANP_0000757 abnormal meiotic anaphase I stage spermatocyte http://purl.obolibrary.org/obo/PLANP_0000445 abnormal spermatocyte Abnormality of meiotic anaphase I stage spermatocyte. http://purl.obolibrary.org/obo/PLANP_0000758 abnormal meiotic telophase I spermatocyte http://purl.obolibrary.org/obo/PLANP_0000445 abnormal spermatocyte Abnormality of meiotic telophase I spermatocyte. http://purl.obolibrary.org/obo/PLANP_0000759 abnormal meiosis II stage spermatocyte http://purl.obolibrary.org/obo/PLANP_0000445 abnormal spermatocyte Abnormality of meiosis II stage spermatocyte. http://purl.obolibrary.org/obo/PLANP_0000760 abnormal meiotic prophase II spermatocyte http://purl.obolibrary.org/obo/PLANP_0000445 abnormal spermatocyte Abnormality of meiotic prophase II spermatocyte. http://purl.obolibrary.org/obo/PLANP_0000761 abnormal meiotic metaphase 2 spermatocyte http://purl.obolibrary.org/obo/PLANP_0000445 abnormal spermatocyte Abnormality of meiotic metaphase 2 spermatocyte. http://purl.obolibrary.org/obo/PLANP_0000762 abnormal meiotic anaphase II spermatocyte http://purl.obolibrary.org/obo/PLANP_0000445 abnormal spermatocyte Abnormality of meiotic anaphase II spermatocyte. http://purl.obolibrary.org/obo/PLANP_0000763 abnormal meiotic telophase II spermatocyte http://purl.obolibrary.org/obo/PLANP_0000445 abnormal spermatocyte Abnormality of meiotic telophase II spermatocyte. http://purl.obolibrary.org/obo/PLANP_0000764 abnormal cephalic ganglia primordium http://purl.obolibrary.org/obo/PLANP_0000270 abnormal primordium Abnormality of cephalic ganglia primordium. http://purl.obolibrary.org/obo/PLANP_0000765 abnormal eye primordium http://purl.obolibrary.org/obo/PLANP_0000270 abnormal primordium Abnormality of eye primordium. http://purl.obolibrary.org/obo/PLANP_0000766 abnormal pharynx primordium http://purl.obolibrary.org/obo/PLANP_0000270 abnormal primordium Abnormality of pharynx primordium. http://purl.obolibrary.org/obo/PLANP_0000767 abnormal pigment cup primordium http://purl.obolibrary.org/obo/PLANP_0000270 abnormal primordium Abnormality of pigment cup primordium. http://purl.obolibrary.org/obo/PLANP_0000768 abnormal testis primordium http://purl.obolibrary.org/obo/PLANP_0000270 abnormal primordium Abnormality of testis primordium. http://purl.obolibrary.org/obo/PLANP_0000769 abnormal gonad primoridium http://purl.obolibrary.org/obo/PLANP_0000270 abnormal primordium Abnormality of gonad primoridium. http://purl.obolibrary.org/obo/PLANP_0000770 abnormal protonephridial lumen http://purl.obolibrary.org/obo/PLANP_0000079 abnormal protonephridia Abnormality of protonephridial lumen. http://purl.obolibrary.org/obo/PLANP_0000771 abnormal testis lumen http://purl.obolibrary.org/obo/PLANP_0000280 abnormal testis Abnormality of testis lumen. http://purl.obolibrary.org/obo/PLANP_0000772 abnormal ovary lumen http://purl.obolibrary.org/obo/PLANP_0000179 abnormal ovary Abnormality of ovary lumen. http://purl.obolibrary.org/obo/PLANP_0000773 abnormal flame cell lumen http://purl.obolibrary.org/obo/PLANP_0000230 abnormal flame cell Abnormality of flame cell lumen. http://purl.obolibrary.org/obo/PLANP_0000774 abnormal cephalic ganglia progenitor cell http://purl.obolibrary.org/obo/PLANP_0000304 abnormal progenitor cell Abnormality of cephalic ganglia progenitor cell. http://purl.obolibrary.org/obo/PLANP_0000775 abnormal dorsal epidermis progenitor cell http://purl.obolibrary.org/obo/PLANP_0000304 abnormal progenitor cell Abnormality of dorsal epidermis progenitor cell. http://purl.obolibrary.org/obo/PLANP_0000776 abnormal optic cup progenitor cell http://purl.obolibrary.org/obo/PLANP_0000304 abnormal progenitor cell Abnormality of optic cup progenitor cell. http://purl.obolibrary.org/obo/PLANP_0000777 abnormal ventral epidermis progenitor cell http://purl.obolibrary.org/obo/PLANP_0000304 abnormal progenitor cell Abnormality of ventral epidermis progenitor cell. http://purl.obolibrary.org/obo/PLANP_0000778 abnormal head fragment http://purl.obolibrary.org/obo/PLANP_0000673 abnormal fragment Abnormality of head fragment. http://purl.obolibrary.org/obo/PLANP_0000779 abnormal trunk fragment http://purl.obolibrary.org/obo/PLANP_0000673 abnormal fragment Abnormality of trunk fragment. http://purl.obolibrary.org/obo/PLANP_0000780 abnormal tail fragment http://purl.obolibrary.org/obo/PLANP_0000673 abnormal fragment Abnormality of tail fragment. http://purl.obolibrary.org/obo/PLANP_0000781 abnormal prepharyngeal fragment http://purl.obolibrary.org/obo/PLANP_0000673 abnormal fragment Abnormality of prepharyngeal fragment. http://purl.obolibrary.org/obo/PLANP_0000782 abnormal postpharyngeal fragment http://purl.obolibrary.org/obo/PLANP_0000673 abnormal fragment Abnormality of postpharyngeal fragment. http://purl.obolibrary.org/obo/PLANP_0000783 abnormal anterior fragment http://purl.obolibrary.org/obo/PLANP_0000673 abnormal fragment Abnormality of anterior fragment. http://purl.obolibrary.org/obo/PLANP_0000784 abnormal posterior fragment http://purl.obolibrary.org/obo/PLANP_0000673 abnormal fragment Abnormality of posterior fragment. http://purl.obolibrary.org/obo/PLANP_0000785 abnormal lateral fragment http://purl.obolibrary.org/obo/PLANP_0000673 abnormal fragment Abnormality of lateral fragment. http://purl.obolibrary.org/obo/PLANP_0000786 abnormal longitudinal fragment http://purl.obolibrary.org/obo/PLANP_0000673 abnormal fragment Abnormality of longitudinal fragment. http://purl.obolibrary.org/obo/PLANP_0000787 abnormal plug fragment http://purl.obolibrary.org/obo/PLANP_0000673 abnormal fragment Abnormality of plug fragment. http://purl.obolibrary.org/obo/PLANP_0000788 abnormal wedge fragment http://purl.obolibrary.org/obo/PLANP_0000673 abnormal fragment Abnormality of wedge fragment. http://purl.obolibrary.org/obo/PLANP_0000789 head regression http://purl.obolibrary.org/obo/PLANP_0000529 loss of head Complete wasting (loss) of head tissue that was once present. http://purl.obolibrary.org/obo/PLANP_0000790 tail regression http://purl.obolibrary.org/obo/PLANP_0000533 loss of tail Complete wasting (loss) of tail tissue that was once present. http://purl.obolibrary.org/obo/PLANP_0000791 decreased mobility of animal http://purl.obolibrary.org/obo/PLANP_0000795 stationary animal Decreased or reduced ability to move whole organism. http://purl.obolibrary.org/obo/PLANP_0000792 long animal http://purl.obolibrary.org/obo/PLANP_0000542 abnormal whole organism longer, increased length of, whole organism http://purl.obolibrary.org/obo/PLANP_0000793 increased pigmentation of the eyes http://purl.obolibrary.org/obo/PLANP_0000534 abnormal pigmentation of the eyes Increased or increasing of pigmentation of eye. http://purl.obolibrary.org/obo/PLANP_0000794 increased pigmentation of the epidermis http://purl.obolibrary.org/obo/PLANP_0000535 abnormal pigmentation of the epidermis Increased or increasing of pigmentation of epidermis. http://purl.obolibrary.org/obo/PLANP_0000795 stationary animal http://purl.obolibrary.org/obo/PLANP_0000542 abnormal whole organism anomaly in the ability to move whole organism. http://purl.obolibrary.org/obo/PLANP_0000796 epithelial ruffles http://purl.obolibrary.org/obo/PLANP_0000665 abnormal epithelium Any structural anomaly that causes epithelium to be ruffled shaped. http://purl.obolibrary.org/obo/PLANP_0000797 pinched head http://purl.obolibrary.org/obo/PLANP_0000499 abnormal shape of head Any structural anomaly that causes head to be hourglass-shaped shaped. http://purl.obolibrary.org/obo/PLANP_0000798 pinched tail http://purl.obolibrary.org/obo/PLANP_0000500 abnormal shape of tail Any structural anomaly that causes tail to be hourglass-shaped shaped. http://purl.obolibrary.org/obo/PLANP_0000799 single sided head pinching http://purl.obolibrary.org/obo/PLANP_0000499 abnormal shape of head Any structural anomaly that causes head to be curved medial shaped. http://purl.obolibrary.org/obo/PLANP_0000800 single sided tail pinching http://purl.obolibrary.org/obo/PLANP_0000500 abnormal shape of tail Any structural anomaly that causes tail to be curved medial shaped. http://purl.obolibrary.org/obo/PLANP_0000801 edema in animal http://purl.obolibrary.org/obo/PLANP_0000542 abnormal whole organism An abnormal accumulation of fluid in the whole organism. http://purl.obolibrary.org/obo/PLANP_0000802 head edema http://purl.obolibrary.org/obo/PLANP_0000497 abnormal morphology of head An abnormal accumulation of fluid in the head. http://purl.obolibrary.org/obo/PLANP_0000803 tail edema http://purl.obolibrary.org/obo/PLANP_0000498 abnormal morphology of tail An abnormal accumulation of fluid in the tail. http://purl.obolibrary.org/obo/PLANP_0000804 underdeveloped eyes http://purl.obolibrary.org/obo/PLANP_0000046 abnormal eye Small, underdeveloped eye. http://purl.obolibrary.org/obo/PLANP_0000805 lesion in animal http://purl.obolibrary.org/obo/PLANP_0000542 abnormal whole organism An abnormal whole organism with one or more lesions. http://purl.obolibrary.org/obo/PLANP_0000806 post-pharyngeal lesion http://purl.obolibrary.org/obo/PLANP_0000662 abnormal post-pharyngeal region An abnormal post-pharyngeal region with one or more lesions. http://purl.obolibrary.org/obo/PLANP_0000807 loss of pigmenation in the head http://purl.obolibrary.org/obo/PLANP_0000810 abnormal pigmentation of the head complete loss of pigmenation of the head. http://purl.obolibrary.org/obo/PLANP_0000808 decreased pigmentation of the head http://purl.obolibrary.org/obo/PLANP_0000810 abnormal pigmentation of the head Decreased or loss of pigmentation of head. http://purl.obolibrary.org/obo/PLANP_0000809 increased pigmentation of the head http://purl.obolibrary.org/obo/PLANP_0000810 abnormal pigmentation of the head Increased or increasing of pigmentation of head. http://purl.obolibrary.org/obo/PLANP_0000810 abnormal pigmentation of the head http://purl.obolibrary.org/obo/PLANP_0000497 abnormal morphology of head abnormal degree of pigmentation of the head. http://purl.obolibrary.org/obo/PATO_0000001 quality http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities http://purl.obolibrary.org/obo/PATO_0000004 mobility http://purl.obolibrary.org/obo/PATO_0001018 physical quality A quality of inhering in a bearer by virtue of the bearer's disposition to move freely. http://purl.obolibrary.org/obo/PATO_0000014 color http://purl.obolibrary.org/obo/PATO_0001300 optical quality A composite chromatic quality composed of hue, saturation and intensity parts. http://purl.obolibrary.org/obo/PATO_0000025 composition http://purl.obolibrary.org/obo/PATO_0000141 structure A single physical entity inhering in an bearer by virtue of the bearer's quantities or relative ratios of subparts. http://purl.obolibrary.org/obo/PATO_0000033 concentration of http://purl.obolibrary.org/obo/PATO_0002182 molecular quality A quality inhering in a substance by virtue of the amount of the bearer's there is mixed with another substance. http://purl.obolibrary.org/obo/PATO_0000040 distance http://purl.obolibrary.org/obo/PATO_0001018 physical quality A quality that is the extent of space between two entities. http://purl.obolibrary.org/obo/PATO_0000051 morphology http://purl.obolibrary.org/obo/BFO_0000019 quality A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure. http://purl.obolibrary.org/obo/PATO_0000052 shape http://purl.obolibrary.org/obo/PATO_0000051 morphology A morphological quality inhering in a bearer by virtue of the bearer's ratios of distances between its features (points, edges, surfaces and also holes etc). http://purl.obolibrary.org/obo/PATO_0000069 deviation (from_normal) http://purl.obolibrary.org/obo/PATO_0000068 qualitative A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. http://purl.obolibrary.org/obo/PATO_0000070 amount http://purl.obolibrary.org/obo/PATO_0000068 qualitative The number of entities of this type that are part of the whole organism. http://purl.obolibrary.org/obo/PATO_0000117 size http://purl.obolibrary.org/obo/PATO_0000051 morphology A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. http://purl.obolibrary.org/obo/PATO_0000128 weight http://purl.obolibrary.org/obo/PATO_0001035 force A physical quality inhering in a bearer that has mass near a gravitational body. http://purl.obolibrary.org/obo/PATO_0000133 orientation http://purl.obolibrary.org/obo/PATO_0000140 position A spatial quality inhering in a bearer by virtue of the bearer's placement which is defined by the angle between the bearer and an axis, or the angle between the bearer and another object. http://purl.obolibrary.org/obo/PATO_0000140 position http://purl.obolibrary.org/obo/PATO_0001018 physical quality A spatial quality inhering in a bearer by virtue of the bearer's spatial location relative to other objects in the vicinity. http://purl.obolibrary.org/obo/PATO_0000141 structure http://purl.obolibrary.org/obo/PATO_0000051 morphology A morphology quality inhering in a bearer by virtue of the bearer's relative position, shape, arrangements and connectivity of an organism's various parts; the pattern underlying its form. http://purl.obolibrary.org/obo/PATO_0000161 rate http://purl.obolibrary.org/obo/PATO_0002062 physical quality of a process A quality of a single process inhering in a bearer by virtue of the bearer's occurrence per unit time. http://purl.obolibrary.org/obo/PATO_0000169 viability http://purl.obolibrary.org/obo/PATO_0001995 organismal quality An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population. http://purl.obolibrary.org/obo/PATO_0000299 mobile http://purl.obolibrary.org/obo/PATO_0000004 mobility A mobility quality of inhering in a bearer by virtue of the bearer's disposition to move freely. http://purl.obolibrary.org/obo/PATO_0000300 immobile http://purl.obolibrary.org/obo/PATO_0000004 mobility A mobility quality inhering in a bearer by virtue of the bearer's being incapable to move freely. http://purl.obolibrary.org/obo/PATO_0000374 increased distance http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A distance which is greater relative to the normal or average. http://purl.obolibrary.org/obo/PATO_0000375 decreased distance http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A distance which is lesser relative to the normal or average. http://purl.obolibrary.org/obo/PATO_0000405 curled http://purl.obolibrary.org/obo/PATO_0000052 shape A shape quality inhering in a bearer by virtue of the bearer's having parallel chains in undulate fashion on the border. http://purl.obolibrary.org/obo/PATO_0000406 curved http://purl.obolibrary.org/obo/PATO_0001591 curvature A curvature quality inhering in a bearer by virtue of the bearer's having or being marked by a curve or smoothly rounded bend. http://purl.obolibrary.org/obo/PATO_0000411 circular http://purl.obolibrary.org/obo/PATO_0000947 elliptic A shape quality inhering in a bearer by virtue of the bearer's being such that every part of the surface or the circumference is equidistant from the center. http://purl.obolibrary.org/obo/PATO_0000460 abnormal http://purl.obolibrary.org/obo/PATO_0000069 deviation (from_normal) A quality inhering in a bearer by virtue of the bearer's deviation from normal or average. http://purl.obolibrary.org/obo/PATO_0000461 normal http://purl.obolibrary.org/obo/PATO_0000068 qualitative A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. http://purl.obolibrary.org/obo/PATO_0000462 absent http://purl.obolibrary.org/obo/PATO_0000070 amount A quality denoting the lack of an entity. http://purl.obolibrary.org/obo/PATO_0000467 present http://purl.obolibrary.org/obo/PATO_0000070 amount A quality inhering in a bearer by virtue of the bearer's existence. http://purl.obolibrary.org/obo/PATO_0000470 increased amount http://purl.obolibrary.org/obo/PATO_0002300 increased quality An amount which is relatively high. http://purl.obolibrary.org/obo/PATO_0000573 increased length http://purl.obolibrary.org/obo/PATO_0000122 length A length quality which is relatively large. http://purl.obolibrary.org/obo/PATO_0000574 decreased length http://purl.obolibrary.org/obo/PATO_0000122 length A length quality which is relatively small. http://purl.obolibrary.org/obo/PATO_0000582 increased weight http://purl.obolibrary.org/obo/PATO_0002245 increased force A weight which is relatively high. http://purl.obolibrary.org/obo/PATO_0000583 decreased weight http://purl.obolibrary.org/obo/PATO_0002246 decreased force A weight which is relatively low. http://purl.obolibrary.org/obo/PATO_0000584 hypertrophic http://purl.obolibrary.org/obo/PATO_0000595 increased volume An increased size quality inhering in a bearer by virtue of the bearer's exhibiting enlargement of a cell or constituent group of cells (for example, organ). http://purl.obolibrary.org/obo/PATO_0000585 hypotrophic http://purl.obolibrary.org/obo/PATO_0000596 decreased volume A decreased size quality inhering in a bearer by virtue of the bearer's exhibiting reduced size of a cell or constituent group of cells (for example, organ). http://purl.obolibrary.org/obo/PATO_0000586 increased size http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A size quality which is relatively high. http://purl.obolibrary.org/obo/PATO_0000587 decreased size http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A size quality which is relatively low. http://purl.obolibrary.org/obo/PATO_0000595 increased volume http://purl.obolibrary.org/obo/PATO_0000918 volume A volume which is relatively high. http://purl.obolibrary.org/obo/PATO_0000596 decreased volume http://purl.obolibrary.org/obo/PATO_0000918 volume A volume which is relatively low. http://purl.obolibrary.org/obo/PATO_0000599 decreased width http://purl.obolibrary.org/obo/PATO_0000921 width A width which is relatively small. http://purl.obolibrary.org/obo/PATO_0000600 increased width http://purl.obolibrary.org/obo/PATO_0000921 width A width which is relatively large. http://purl.obolibrary.org/obo/PATO_0000639 degenerate http://purl.obolibrary.org/obo/PATO_0002037 degeneration A structural quality inhering in a bearer whose structure deteriorates or is lost over time due to an active pathological process. http://purl.obolibrary.org/obo/PATO_0000644 hyperplastic http://purl.obolibrary.org/obo/PATO_0000586 increased size A increased size quality inhering in an organ or tissue by virtue of the bearer's exhibiting increased number of cells. http://purl.obolibrary.org/obo/PATO_0000645 hypoplastic http://purl.obolibrary.org/obo/PATO_0002290 aplastic/hypoplastic A decreased size quality inhering in a bearer by virtue of the bearer's exhibiting reduced number of cells within an organ or tissue. http://purl.obolibrary.org/obo/PATO_0000911 decreased rate http://purl.obolibrary.org/obo/PATO_0002302 decreased process quality A rate which is relatively low. http://purl.obolibrary.org/obo/PATO_0000912 increased rate http://purl.obolibrary.org/obo/PATO_0002304 increased process quality A rate which is relatively high. http://purl.obolibrary.org/obo/PATO_0000921 width http://purl.obolibrary.org/obo/PATO_0001708 1-D extent A 1-D extent quality which is equal to the distance from one side of an object to another side which is opposite. http://purl.obolibrary.org/obo/PATO_0000944 sharpness http://purl.obolibrary.org/obo/PATO_0000052 shape A shape quality inhering in a bearer by virtue of the bearer's having a sharp or tapered end or point. http://purl.obolibrary.org/obo/PATO_0000947 elliptic http://purl.obolibrary.org/obo/PATO_0002318 superelliptic A spheroid quality inhering in a bearer by virtue of the bearer's being oval with two axes of symmetry, as produced by a conical section. http://purl.obolibrary.org/obo/PATO_0001018 physical quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities. http://purl.obolibrary.org/obo/PATO_0001035 force http://purl.obolibrary.org/obo/PATO_0001018 physical quality A physical quality inhering in a bearer by virtue of the bearer's rate of change of momentum. http://purl.obolibrary.org/obo/PATO_0001159 concentrated http://purl.obolibrary.org/obo/PATO_0000033 concentration of A concentration quality inhering in a bearer by virtue of the bearer's exhibiting concentration. http://purl.obolibrary.org/obo/PATO_0001162 increased concentration http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A concentration which is higher relative to the normal or average. http://purl.obolibrary.org/obo/PATO_0001163 decreased concentration http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A concentration which is lower relative to the normal or average. http://purl.obolibrary.org/obo/PATO_0001199 linear http://purl.obolibrary.org/obo/PATO_0000052 shape A shape quality inhering in a bearer by virtue of the bearer's being narrow, with the two opposite margins parallel. http://purl.obolibrary.org/obo/PATO_0001236 process quality http://purl.obolibrary.org/obo/PATO_0000001 quality A quality which inheres in an process. http://purl.obolibrary.org/obo/PATO_0001241 physical object quality http://purl.obolibrary.org/obo/PATO_0000001 quality A quality which inheres in a continuant. http://purl.obolibrary.org/obo/PATO_0001291 electromagnetic (EM) radiation quality http://purl.obolibrary.org/obo/PATO_0001739 radiation quality A physical quality that inheres in an bearer by virtue of how that bearer interacts with electromagnetic radiation. http://purl.obolibrary.org/obo/PATO_0001300 optical quality http://purl.obolibrary.org/obo/PATO_0001291 electromagnetic (EM) radiation quality An EM radiation quality in which the EM radiation is within the fiat range of the spectrum visible deemed to be light. http://purl.obolibrary.org/obo/PATO_0001355 convex http://purl.obolibrary.org/obo/PATO_0002005 concavity A shape quality that obtains by virtue of the bearer having inward facing edges; having a surface or boundary that curves or bulges outward, as the exterior of a sphere. http://purl.obolibrary.org/obo/PATO_0001381 triploid http://purl.obolibrary.org/obo/PATO_0001377 polyploid A polyploidy quality inhering in a bearer by virtue of the bearer's containing three homologous sets of chromosomes. http://purl.obolibrary.org/obo/PATO_0001382 tetraploid http://purl.obolibrary.org/obo/PATO_0001377 polyploid A polyploidy quality inhering in a bearer by virtue of the bearer's containing four homologous sets of chromosomes. http://purl.obolibrary.org/obo/PATO_0001384 hexaploid http://purl.obolibrary.org/obo/PATO_0001377 polyploid A polyploidy quality inhering in a bearer by virtue of the bearer's containing six homologous sets of chromosomes. http://purl.obolibrary.org/obo/PATO_0001393 euploid http://purl.obolibrary.org/obo/PATO_0001374 ploidy A ploidy quality inhering in a bearer by virtue of the bearer's containing an integral multiple of the monoploid number, possibly excluding the sex-determining chromosomes. http://purl.obolibrary.org/obo/PATO_0001404 nucleate quality http://purl.obolibrary.org/obo/PATO_0001396 cellular quality A cellular quality inhering in a bearer by virtue of bearer's number of nuclei. http://purl.obolibrary.org/obo/PATO_0001405 anucleate http://purl.obolibrary.org/obo/PATO_0001404 nucleate quality A nucleate quality inhering in a bearer by virtue of the bearer's having no nucleus. http://purl.obolibrary.org/obo/PATO_0001406 binucleate http://purl.obolibrary.org/obo/PATO_0001908 multinucleate A nucleate quality inhering in a bearer by virtue of the bearer's having two nuclei. http://purl.obolibrary.org/obo/PATO_0001407 mononucleate http://purl.obolibrary.org/obo/PATO_0002505 nucleated A nucleate quality inhering in a bearer by virtue of the bearer's having one nucleus. http://purl.obolibrary.org/obo/PATO_0001408 ciliatedness http://purl.obolibrary.org/obo/PATO_0001396 cellular quality A cellular quality inhering in a bearer by virtue of the bearer's having thin, tail-like projections extending outwards from the cell body. http://purl.obolibrary.org/obo/PATO_0001419 sharp http://purl.obolibrary.org/obo/PATO_0000944 sharpness A shape quality inhering in a bearer by virtue of the bearer's terminating in a point or edge. http://purl.obolibrary.org/obo/PATO_0001450 edematous http://purl.obolibrary.org/obo/PATO_0000025 composition A structural quality which is held by a bearer when the latter exhibits an excessive accumulation of extracellular fluid. http://purl.obolibrary.org/obo/PATO_0001475 increased position http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A position which is relatively high. http://purl.obolibrary.org/obo/PATO_0001476 decreased position http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A positional which is relatively low. http://purl.obolibrary.org/obo/PATO_0001555 has number of http://purl.obolibrary.org/obo/PATO_0001241 physical object quality The number of parts of a particular type that the bearer entity has. This is a relational quality, and thus holds between two entities: the bearer of the quality, and the type of parts. http://purl.obolibrary.org/obo/PATO_0001558 lacking processual parts http://purl.obolibrary.org/obo/PATO_0001564 extra or missing processual parts A quality of a process inhering in a bearer by virtue of the bearer's lacking a processual part as specified by the additional entity. http://purl.obolibrary.org/obo/PATO_0001561 having extra processual parts http://purl.obolibrary.org/obo/PATO_0001564 extra or missing processual parts A quality of a process inhering in a bearer by virtue of the bearer's having additional processual parts. http://purl.obolibrary.org/obo/PATO_0001562 decreased mass http://purl.obolibrary.org/obo/PATO_0000125 mass A mass which is lower than normal or average. http://purl.obolibrary.org/obo/PATO_0001563 increased mass http://purl.obolibrary.org/obo/PATO_0000125 mass A mass which is higher than normal or average. http://purl.obolibrary.org/obo/PATO_0001564 extra or missing processual parts http://purl.obolibrary.org/obo/PATO_0001236 process quality A quality of a process inhering in a bearer by virtue of the bearer's processual parts. http://purl.obolibrary.org/obo/PATO_0001591 curvature http://purl.obolibrary.org/obo/PATO_0000052 shape A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. http://purl.obolibrary.org/obo/PATO_0001592 increased curvature http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A curvature which is relatively high. http://purl.obolibrary.org/obo/PATO_0001593 decreased curvature http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A curvature which is relatively low. http://purl.obolibrary.org/obo/PATO_0001708 1-D extent http://purl.obolibrary.org/obo/PATO_0000117 size A size quality inhering in an bearer by virtue of the bearer's extension in one dimension. http://purl.obolibrary.org/obo/PATO_0001710 3-D extent http://purl.obolibrary.org/obo/PATO_0000117 size A size quality inhering in an bearer by virtue of the bearer's extension in three dimensions. http://purl.obolibrary.org/obo/PATO_0001739 radiation quality http://purl.obolibrary.org/obo/PATO_0001018 physical quality A quality that inheres in an bearer by virtue of how that bearer interacts with radiation. http://purl.obolibrary.org/obo/PATO_0001799 ruffled http://purl.obolibrary.org/obo/PATO_0000052 shape A shape quality inhering in a bearer by virtue of the bearer's exhibiting disturbance of its smoothness or regularity. http://purl.obolibrary.org/obo/PATO_0001857 concave http://purl.obolibrary.org/obo/PATO_0002005 concavity A shape quality in a bearer by virtue of the bearer's curving inward. http://purl.obolibrary.org/obo/PATO_0001869 pathological http://purl.obolibrary.org/obo/PATO_0000460 abnormal A quality inhering in a bearer by virtue of the bearer's being abnormal and having a destructive effect on living tissue. http://purl.obolibrary.org/obo/PATO_0001875 triangular http://purl.obolibrary.org/obo/PATO_0002006 2-D shape A shape quality inhering in a bearer by virtue of the bearer's having three angles. http://purl.obolibrary.org/obo/PATO_0001894 phenotypic sex http://purl.obolibrary.org/obo/PATO_0000047 biological sex An organismal quality inhering in a bearer by virtue of the bearer's physical expression of sexual characteristics. http://purl.obolibrary.org/obo/PATO_0001908 multinucleate http://purl.obolibrary.org/obo/PATO_0002505 nucleated A nucleate quality inhering in a bearer by virtue of the bearer's having more than one nucleus. http://purl.obolibrary.org/obo/PATO_0001955 cuneate http://purl.obolibrary.org/obo/PATO_0001875 triangular A shape quality inhering in a bearer by virtue of the bearer's being narrowly triangular, wider at the apex and tapering toward the base. http://purl.obolibrary.org/obo/PATO_0001992 cellularity http://purl.obolibrary.org/obo/PATO_0001995 organismal quality An organismal quality inhering in a bearer by virtue of the bearer's consisting cells. http://purl.obolibrary.org/obo/PATO_0001993 multicellular http://purl.obolibrary.org/obo/PATO_0001992 cellularity A cellularity quality inhering in a bearer by virtue of the bearer's consisting of more than one cell. http://purl.obolibrary.org/obo/PATO_0001997 decreased amount http://purl.obolibrary.org/obo/PATO_0002301 decreased quality An amount which is relatively low. http://purl.obolibrary.org/obo/PATO_0001999 lacks parts or has fewer parts of type http://purl.obolibrary.org/obo/PATO_0002083 altered number of The bearer of this quality has_part < n of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly. This case includes the limit case, where the bearer lacks all parts of the specified type. http://purl.obolibrary.org/obo/PATO_0002000 lacks all parts of type http://purl.obolibrary.org/obo/PATO_0001999 lacks parts or has fewer parts of type A quality of physical entities inhering in a bearer by virtue of the bearer's lacking a physical part as specified by the additional entity. http://purl.obolibrary.org/obo/PATO_0002001 has fewer parts of type http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality The bearer of this quality has_part < n AND has_part > 0 of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly. http://purl.obolibrary.org/obo/PATO_0002002 has extra parts of type http://purl.obolibrary.org/obo/PATO_0002305 increased object quality The bearer of this quality has_part > n of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. http://purl.obolibrary.org/obo/PATO_0002005 concavity http://purl.obolibrary.org/obo/PATO_0000052 shape Surface shape that refers to the inward or outward curvature of the surface. http://purl.obolibrary.org/obo/PATO_0002006 2-D shape http://purl.obolibrary.org/obo/PATO_0000052 shape A shape that inheres in a 2 dimensional entity, such as a cross section or projection of a 3 dimensional entity. http://purl.obolibrary.org/obo/PATO_0002007 convex 3-D shape http://purl.obolibrary.org/obo/PATO_0002266 3-D shape A complete three dimensional shape in which for every line connecting pair of points on the object is within the object. Or: a shape lacking cavities. Contrast: concave. http://purl.obolibrary.org/obo/PATO_0002008 concave 3-D shape http://purl.obolibrary.org/obo/PATO_0002266 3-D shape A complete three dimensional shape in which there is a line connecting pair of points on the object that lies outside the object. Or: a shape with cavities. Contrast: concave. http://purl.obolibrary.org/obo/PATO_0002037 degeneration http://purl.obolibrary.org/obo/PATO_0000141 structure A structural quality inhering in a bearer by virtue of the bearer exhibiting deterioration of its structure. http://purl.obolibrary.org/obo/PATO_0002038 non-degenerate http://purl.obolibrary.org/obo/PATO_0002037 degeneration A structural quality inhering in a bearer whose structure which does not deteriorate. http://purl.obolibrary.org/obo/PATO_0002063 columnar http://purl.obolibrary.org/obo/PATO_0000052 shape A shape inhering in a bearer by virtue of the bearer's being elongated and cylindrical. http://purl.obolibrary.org/obo/PATO_0002065 star shaped http://purl.obolibrary.org/obo/PATO_0000052 shape A shape quality inhering in a bearer by virtue of the bearer's being arranged like rays or radii; radiating from a common center. http://purl.obolibrary.org/obo/PATO_0002083 altered number of http://purl.obolibrary.org/obo/PATO_0001555 has number of Having extra or fewer parts. http://purl.obolibrary.org/obo/PATO_0002131 abduction http://purl.obolibrary.org/obo/PATO_0002168 displaced to A displaced angular placement quality inhering in a body part by virtue of the bearer's movement away from the medial plane of the body. http://purl.obolibrary.org/obo/PATO_0002133 adduction http://purl.obolibrary.org/obo/PATO_0002168 displaced to A displaced angular placement quality inhering in a body part by virtue of the bearer's movement closer the medial plane of the body. http://purl.obolibrary.org/obo/PATO_0002164 curved medial http://purl.obolibrary.org/obo/PATO_0000406 curved A curvature quality inhering in a bearer by virtue of the bearer's being curved towards the middle. http://purl.obolibrary.org/obo/PATO_0002168 displaced to http://purl.obolibrary.org/obo/PATO_0000133 orientation An angular placement quality inhering in a bearer by virtue of the bearer being changed in position in relation to another entity. http://purl.obolibrary.org/obo/PATO_0002182 molecular quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality which inheres in a molecular entity, a single molecule, atom, ion, radical etc. http://purl.obolibrary.org/obo/PATO_0002239 hourglass-shaped http://purl.obolibrary.org/obo/PATO_0002008 concave 3-D shape A concave 3-D shape that inheres in the bearer by virtue of the bearer's nearly) symmetric shape wide at its ends and narrow in the middle, resembling the figure of number 8. http://purl.obolibrary.org/obo/PATO_0002245 increased force http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A force which relative high. http://purl.obolibrary.org/obo/PATO_0002246 decreased force http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A force which is relative low. http://purl.obolibrary.org/obo/PATO_0002247 degree of pigmentation http://purl.obolibrary.org/obo/PATO_0000141 structure A quality inhering in a bearer by virtue of the bearer's having or lacking of substances produced by living organisms that have a color resulting from selective color absorption. http://purl.obolibrary.org/obo/PATO_0002248 pigmented http://purl.obolibrary.org/obo/PATO_0002247 degree of pigmentation A degree of pigmentation quality inhering in a bearer by virtue of the bearer's having substances produced by living organisms that have a color resulting from selective color absorption. http://purl.obolibrary.org/obo/PATO_0002249 unpigmented http://purl.obolibrary.org/obo/PATO_0002247 degree of pigmentation A degree of pigmentation quality inhering in a bearer by virtue of the bearer's lacking substances produced by living organisms that have a color resulting from selective color absorption. http://purl.obolibrary.org/obo/PATO_0002250 increased pigmentation http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A degree of pigmentation quality that is relatively high. http://purl.obolibrary.org/obo/PATO_0002251 decreased pigmentation http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A degree of pigmentation quality that is relative low. http://purl.obolibrary.org/obo/PATO_0002258 pointed http://purl.obolibrary.org/obo/PATO_0001419 sharp A shape quality inhering in a bearer by virtue of the bearer's having a point. http://purl.obolibrary.org/obo/PATO_0002266 3-D shape http://purl.obolibrary.org/obo/PATO_0000052 shape A shape that inheres in a 3 dimensional entity. http://purl.obolibrary.org/obo/PATO_0002282 increased mobility http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A mobility which is relative high. http://purl.obolibrary.org/obo/PATO_0002283 decreased mobility http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A mobility which is relative low. http://purl.obolibrary.org/obo/PATO_0002300 increased quality http://purl.obolibrary.org/obo/PATO_0000069 deviation (from_normal) A quality that has a value that is increased compared to normal or average. http://purl.obolibrary.org/obo/PATO_0002301 decreased quality http://purl.obolibrary.org/obo/PATO_0000069 deviation (from_normal) A quality that has a value that is decreased compared to normal or average. http://purl.obolibrary.org/obo/PATO_0002302 decreased process quality http://purl.obolibrary.org/obo/PATO_0002301 decreased quality A quality of a process that has a value that is decreased compared to normal or average. http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality http://purl.obolibrary.org/obo/PATO_0002301 decreased quality A quality of an object that has a value that is decreased compared to normal or average. http://purl.obolibrary.org/obo/PATO_0002304 increased process quality http://purl.obolibrary.org/obo/PATO_0002300 increased quality A quality of a process that has a value that is increased compared to normal or average. http://purl.obolibrary.org/obo/PATO_0002305 increased object quality http://purl.obolibrary.org/obo/PATO_0002300 increased quality A quality of an object that has a value that is increased compared to normal or average. http://purl.obolibrary.org/obo/PATO_0002318 superelliptic http://purl.obolibrary.org/obo/PATO_0002006 2-D shape A shape constituting a transition between a rectangle and a circle; a closed curve, of which the circle and ellipse are special cases, whose parametric equation is x = a.cos2/rt, y = b.cos2/rt http://purl.obolibrary.org/obo/PATO_0002486 multi-organismal process quality http://purl.obolibrary.org/obo/PATO_0001236 process quality A quality inhering in a process by virtue of that process having two or more organisms as participants. http://purl.obolibrary.org/obo/PATO_0002487 single organismal process quality http://purl.obolibrary.org/obo/PATO_0001236 process quality A quality inhering in a process by virtue of that process having exactly one organism as a participant. http://purl.obolibrary.org/obo/PATO_0002505 nucleated http://purl.obolibrary.org/obo/PATO_0001404 nucleate quality A nucleate quality inhering in a bearer by virtue of the bearer's having one or more nucleus. http://purl.obolibrary.org/obo/PATO_0005024 longitudinal orientation http://purl.obolibrary.org/obo/PATO_0000133 orientation An orientation quality inhering in a bearer by virtue of the bearer having a position that is directed along the longitudinal or anterior-posterior axis. http://purl.obolibrary.org/obo/PATO_0015001 absence due to degeneration http://purl.obolibrary.org/obo/PATO_0000639 degenerate Absence due to a degenerative process. http://purl.obolibrary.org/obo/UBERON_0035086 plane of autotomy http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity An anatomical plane that bisects a zone of weakness in an appendage. When autotamy occurs, the appendage divides along this plane. http://purl.obolibrary.org/obo/GO_0140112 extracellular vesicle biogenesis http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content. http://purl.obolibrary.org/obo/GO_0140297 DNA-binding transcription factor binding http://purl.obolibrary.org/obo/GO_0008134 transcription factor binding Interacting selectively and non-covalently with a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. http://purl.obolibrary.org/obo/GO_0140352 export from cell http://purl.obolibrary.org/obo/GO_0009987 cellular process The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis. http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything. http://purl.obolibrary.org/obo/BFO_0000015 process http://purl.obolibrary.org/obo/BFO_0000003 occurrent An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. http://purl.obolibrary.org/obo/BFO_0000017 realizable entity http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances. http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same. http://purl.obolibrary.org/obo/BFO_0000031 generically dependent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time. http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/BFO_0000004 independent continuant An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time. http://purl.obolibrary.org/obo/OGMS_0000031 disease http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism. http://purl.obolibrary.org/obo/PATO_0000047 biological sex http://purl.obolibrary.org/obo/PATO_0001995 organismal quality An organismal quality inhering in a bearer by virtue of the bearer's ability to undergo sexual reproduction in order to differentiate the individuals or types involved. http://purl.obolibrary.org/obo/PATO_0000122 length http://purl.obolibrary.org/obo/PATO_0001708 1-D extent A 1-D extent quality which is equal to the distance between two points. http://purl.obolibrary.org/obo/PATO_0000125 mass http://purl.obolibrary.org/obo/PATO_0001018 physical quality A physical quality that inheres in a bearer by virtue of the proportion of the bearer's amount of matter. http://purl.obolibrary.org/obo/PATO_0000383 female http://purl.obolibrary.org/obo/PATO_0001894 phenotypic sex A biological sex quality inhering in an individual or a population that only produces gametes that can be fertilised by male gametes. http://purl.obolibrary.org/obo/PATO_0000384 male http://purl.obolibrary.org/obo/PATO_0001894 phenotypic sex A biological sex quality inhering in an individual or a population whose sex organs contain only male gametes. http://purl.obolibrary.org/obo/PATO_0000918 volume http://purl.obolibrary.org/obo/PATO_0001710 3-D extent A 3-D extent quality inhering in a bearer by virtue of the bearer's amount of 3-dimensional space it occupies. http://purl.obolibrary.org/obo/PATO_0001340 hermaphrodite http://purl.obolibrary.org/obo/PATO_0001894 phenotypic sex A biological sex quality inhering in an organism or a population with both male and female sexual organs in one individual. http://purl.obolibrary.org/obo/PATO_0001374 ploidy http://purl.obolibrary.org/obo/PATO_0001396 cellular quality A cellular quality inhering in a bearer by virtue of the bearer's number of homologous sets of chromosomes in the nucleus or primary chromosome-containing compartment of the cell, each set essentially coding for all the biological traits of the organism. http://purl.obolibrary.org/obo/PATO_0001377 polyploid http://purl.obolibrary.org/obo/PATO_0001393 euploid A ploidy quality inhering in a bearer by virtue of the bearer's containing more than two homologous sets of chromosomes. http://purl.obolibrary.org/obo/PATO_0001396 cellular quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A monadic quality of continuant that exists at the cellular level of organisation. http://purl.obolibrary.org/obo/PATO_0001421 alive http://purl.obolibrary.org/obo/PATO_0000169 viability A viability quality inhering in a bearer by virtue of the bearer's condition before death. http://purl.obolibrary.org/obo/PATO_0001422 dead http://purl.obolibrary.org/obo/PATO_0000169 viability A viability quality inhering in a bearer by virtue of the cessation of the bearer's life. http://purl.obolibrary.org/obo/PATO_0001995 organismal quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality that inheres in an entire organism or part of an organism. http://purl.obolibrary.org/obo/GO_0140014 mitotic nuclear division http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell. http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization http://purl.obolibrary.org/obo/GO_0030030 cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon. http://purl.obolibrary.org/obo/GO_0062013 positive regulation of small molecule metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process. http://purl.obolibrary.org/obo/GO_0062014 negative regulation of small molecule metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process. http://purl.obolibrary.org/obo/PLANA_0007556 embryonic pharynx lumen http://purl.obolibrary.org/obo/PLANA_0002053 lumen A lumen enclosed by the embryonic pharynx epithelial cells through which yolk cells are transported into the embryonic gut cavity. http://purl.obolibrary.org/obo/PLANA_0007550 serotonergic neural progenitor cell http://purl.obolibrary.org/obo/PLANA_0000012 neural progenitor cell piwi-1+, lhx1/5-1+, pitx+ progenitor neoblasts required for specification of tph+ serotonergic neurons. http://purl.obolibrary.org/obo/GO_0106121 positive regulation of cobalamin metabolic process http://purl.obolibrary.org/obo/GO_0106064 regulation of cobalamin metabolic process Any process that activates or increases the frequency, rate or extent of a cobalamin metabolic process. http://purl.obolibrary.org/obo/GO_0106122 negative regulation of cobalamin metabolic process http://purl.obolibrary.org/obo/GO_0106064 regulation of cobalamin metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of a cobalamin metabolic process. http://purl.obolibrary.org/obo/GO_0110110 positive regulation of animal organ morphogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis. http://purl.obolibrary.org/obo/GO_0110111 negative regulation of animal organ morphogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis. http://purl.obolibrary.org/obo/PLANA_0007543 TrpA+ central nervous system neuron http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A subset of TrpA+ neurons, located medially in the cephalic ganglia, whose formation is dependent on function of runt-1 and ap2. http://purl.obolibrary.org/obo/GO_0005215 transporter activity http://purl.obolibrary.org/obo/GO_0003674 molecular_function Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells. http://purl.obolibrary.org/obo/GO_0005310 dicarboxylic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0046943 carboxylic acid transmembrane transporter activity Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups. http://purl.obolibrary.org/obo/GO_0005342 organic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage, http://purl.obolibrary.org/obo/GO_0005576 extracellular region http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. http://purl.obolibrary.org/obo/GO_0005615 extracellular space http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. http://purl.obolibrary.org/obo/GO_0005618 cell wall http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins. http://purl.obolibrary.org/obo/GO_0005623 cell http://purl.obolibrary.org/obo/GO_0005575 cellular_component The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. http://purl.obolibrary.org/obo/GO_0005730 nucleolus http://purl.obolibrary.org/obo/GO_0043232 intracellular non-membrane-bounded organelle A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. http://purl.obolibrary.org/obo/GO_0005740 mitochondrial envelope http://purl.obolibrary.org/obo/GO_0031967 organelle envelope The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space. http://purl.obolibrary.org/obo/GO_0005758 mitochondrial intermembrane space http://purl.obolibrary.org/obo/GO_0031970 organelle envelope lumen The region between the inner and outer lipid bilayers of the mitochondrial envelope. http://purl.obolibrary.org/obo/GO_0005759 mitochondrial matrix http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation. http://purl.obolibrary.org/obo/GO_0005788 endoplasmic reticulum lumen http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen The volume enclosed by the membranes of the endoplasmic reticulum. http://purl.obolibrary.org/obo/GO_0005790 smooth endoplasmic reticulum http://purl.obolibrary.org/obo/GO_0005783 endoplasmic reticulum The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER. http://purl.obolibrary.org/obo/GO_0005791 rough endoplasmic reticulum http://purl.obolibrary.org/obo/GO_0005783 endoplasmic reticulum The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae. http://purl.obolibrary.org/obo/GO_0005794 Golgi apparatus http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions. http://purl.obolibrary.org/obo/GO_0005798 Golgi-associated vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell. http://purl.obolibrary.org/obo/GO_0005801 cis-Golgi network http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum. http://purl.obolibrary.org/obo/GO_0005811 lipid droplet http://purl.obolibrary.org/obo/GO_0043232 intracellular non-membrane-bounded organelle An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins. http://purl.obolibrary.org/obo/GO_0005844 polysome http://purl.obolibrary.org/obo/GO_1990904 ribonucleoprotein complex A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro. http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton http://purl.obolibrary.org/obo/GO_0043232 intracellular non-membrane-bounded organelle Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. http://purl.obolibrary.org/obo/GO_0005929 cilium http://purl.obolibrary.org/obo/GO_0043226 organelle A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body. http://purl.obolibrary.org/obo/GO_0005938 cell cortex http://purl.obolibrary.org/obo/GO_0005737 cytoplasm The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins. http://purl.obolibrary.org/obo/GO_0005975 carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0071704 organic substance metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule. http://purl.obolibrary.org/obo/GO_0006082 organic acid metabolic process http://purl.obolibrary.org/obo/GO_0044237 cellular metabolic process The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0006109 regulation of carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates. http://purl.obolibrary.org/obo/GO_0006139 nucleobase-containing compound metabolic process http://purl.obolibrary.org/obo/GO_1901360 organic cyclic compound metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0006140 regulation of nucleotide metabolic process http://purl.obolibrary.org/obo/GO_0062012 regulation of small molecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides. http://purl.obolibrary.org/obo/GO_0006163 purine nucleotide metabolic process http://purl.obolibrary.org/obo/GO_0072521 purine-containing compound metabolic process The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/GO_0006164 purine nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0072522 purine-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/GO_0006304 DNA modification http://purl.obolibrary.org/obo/GO_0006259 DNA metabolic process The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties. http://purl.obolibrary.org/obo/GO_0006305 DNA alkylation http://purl.obolibrary.org/obo/GO_0006304 DNA modification The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis. http://purl.obolibrary.org/obo/GO_0006306 DNA methylation http://purl.obolibrary.org/obo/GO_0043414 macromolecule methylation The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine. http://purl.obolibrary.org/obo/GO_0006323 DNA packaging http://purl.obolibrary.org/obo/GO_0071103 DNA conformation change Any process in which DNA and associated proteins are formed into a compact, orderly structure. http://purl.obolibrary.org/obo/GO_0006486 protein glycosylation http://purl.obolibrary.org/obo/GO_0006464 cellular protein modification process A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins. http://purl.obolibrary.org/obo/GO_0006487 protein N-linked glycosylation http://purl.obolibrary.org/obo/GO_0006486 protein glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan. http://purl.obolibrary.org/obo/GO_0006629 lipid metabolic process http://purl.obolibrary.org/obo/GO_0071704 organic substance metabolic process The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. http://purl.obolibrary.org/obo/GO_0006720 isoprenoid metabolic process http://purl.obolibrary.org/obo/GO_0044255 cellular lipid metabolic process The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. http://purl.obolibrary.org/obo/GO_0006721 terpenoid metabolic process http://purl.obolibrary.org/obo/GO_0006720 isoprenoid metabolic process The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups. http://purl.obolibrary.org/obo/GO_0006725 cellular aromatic compound metabolic process http://purl.obolibrary.org/obo/GO_0044237 cellular metabolic process The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells. http://purl.obolibrary.org/obo/GO_0006732 coenzyme metabolic process http://purl.obolibrary.org/obo/GO_0051186 cofactor metabolic process The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed. http://purl.obolibrary.org/obo/GO_0006753 nucleoside phosphate metabolic process http://purl.obolibrary.org/obo/GO_0055086 nucleobase-containing small molecule metabolic process The chemical reactions and pathways involving any phosphorylated nucleoside. http://purl.obolibrary.org/obo/GO_0006754 ATP biosynthetic process http://purl.obolibrary.org/obo/GO_0017144 drug metabolic process The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. http://purl.obolibrary.org/obo/GO_0006760 folic acid-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0043603 cellular amide metabolic process The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units. http://purl.obolibrary.org/obo/GO_0006766 vitamin metabolic process http://purl.obolibrary.org/obo/GO_0044281 small molecule metabolic process The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems. http://purl.obolibrary.org/obo/GO_0006767 water-soluble vitamin metabolic process http://purl.obolibrary.org/obo/GO_0006766 vitamin metabolic process The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in water. http://purl.obolibrary.org/obo/GO_0006768 biotin metabolic process http://purl.obolibrary.org/obo/GO_0017144 drug metabolic process The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions. http://purl.obolibrary.org/obo/GO_0006772 thiamine metabolic process http://purl.obolibrary.org/obo/GO_0042723 thiamine-containing compound metabolic process The chemical reactions and pathways involving thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver. http://purl.obolibrary.org/obo/GO_0006775 fat-soluble vitamin metabolic process http://purl.obolibrary.org/obo/GO_0006766 vitamin metabolic process The chemical reactions and pathways involving of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water. http://purl.obolibrary.org/obo/GO_0006776 vitamin A metabolic process http://purl.obolibrary.org/obo/GO_0001523 retinoid metabolic process The chemical reactions and pathways involving any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid, all of which are derivatives of beta-carotene. http://purl.obolibrary.org/obo/GO_0006793 phosphorus metabolic process http://purl.obolibrary.org/obo/GO_0044237 cellular metabolic process The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4). http://purl.obolibrary.org/obo/GO_0006796 phosphate-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0006793 phosphorus metabolic process The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid. http://purl.obolibrary.org/obo/GO_0006807 nitrogen compound metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen. http://purl.obolibrary.org/obo/GO_0006810 transport http://purl.obolibrary.org/obo/GO_0051234 establishment of localization The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein. http://purl.obolibrary.org/obo/GO_0006811 ion transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0006820 anion transport http://purl.obolibrary.org/obo/GO_0006811 ion transport The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0006835 dicarboxylic acid transport http://purl.obolibrary.org/obo/GO_0046942 carboxylic acid transport The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0006855 drug transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which a drug is transported across a membrane. http://purl.obolibrary.org/obo/GO_0006858 extracellular transport http://purl.obolibrary.org/obo/GO_0006810 transport The transport of substances that occurs outside cells. http://purl.obolibrary.org/obo/GO_0006873 cellular ion homeostasis http://purl.obolibrary.org/obo/GO_0055082 cellular chemical homeostasis Any process involved in the maintenance of an internal steady state of ions at the level of a cell. http://purl.obolibrary.org/obo/GO_0006874 cellular calcium ion homeostasis http://purl.obolibrary.org/obo/GO_0072503 cellular divalent inorganic cation homeostasis Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell. http://purl.obolibrary.org/obo/GO_0006875 cellular metal ion homeostasis http://purl.obolibrary.org/obo/GO_0055065 metal ion homeostasis Any process involved in the maintenance of an internal steady state of metal ions at the level of a cell. http://purl.obolibrary.org/obo/GO_0006900 vesicle budding from membrane http://purl.obolibrary.org/obo/GO_0016050 vesicle organization The evagination of a membrane, resulting in formation of a vesicle. http://purl.obolibrary.org/obo/GO_0006903 vesicle targeting http://purl.obolibrary.org/obo/GO_0009987 cellular process The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo. http://purl.obolibrary.org/obo/GO_0006921 cellular component disassembly involved in execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0022411 cellular component disassembly The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis. http://purl.obolibrary.org/obo/GO_0006928 movement of cell or subcellular component http://purl.obolibrary.org/obo/GO_0009987 cellular process The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore. http://purl.obolibrary.org/obo/GO_0006970 response to osmotic stress http://purl.obolibrary.org/obo/GO_0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. http://purl.obolibrary.org/obo/GO_0006972 hyperosmotic response http://purl.obolibrary.org/obo/GO_0006970 response to osmotic stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell. http://purl.obolibrary.org/obo/GO_0006996 organelle organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0007006 mitochondrial membrane organization http://purl.obolibrary.org/obo/GO_0007005 mitochondrion organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion. http://purl.obolibrary.org/obo/GO_0007036 vacuolar calcium ion homeostasis http://purl.obolibrary.org/obo/GO_0006874 cellular calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings. http://purl.obolibrary.org/obo/GO_0007053 spindle assembly involved in male meiosis http://purl.obolibrary.org/obo/GO_0022412 cellular process involved in reproduction in multicellular organism The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0007055 spindle assembly involved in male meiosis II http://purl.obolibrary.org/obo/GO_0007053 spindle assembly involved in male meiosis The formation of the spindle during meiosis II of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0007056 spindle assembly involved in female meiosis http://purl.obolibrary.org/obo/GO_0022412 cellular process involved in reproduction in multicellular organism The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0007058 spindle assembly involved in female meiosis II http://purl.obolibrary.org/obo/GO_0007056 spindle assembly involved in female meiosis The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis II of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0007059 chromosome segregation http://purl.obolibrary.org/obo/GO_0009987 cellular process The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. http://purl.obolibrary.org/obo/GO_0007076 mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells. http://purl.obolibrary.org/obo/GO_0007088 regulation of mitotic nuclear division http://purl.obolibrary.org/obo/GO_0051783 regulation of nuclear division Any process that modulates the frequency, rate or extent of mitosis. http://purl.obolibrary.org/obo/GO_0007132 meiotic metaphase I http://purl.obolibrary.org/obo/GO_0098764 meiosis I cell cycle phase The cell cycle phase, following prophase I, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis I. http://purl.obolibrary.org/obo/GO_0007133 meiotic anaphase I http://purl.obolibrary.org/obo/GO_0098764 meiosis I cell cycle phase The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis I. http://purl.obolibrary.org/obo/GO_0007134 meiotic telophase I http://purl.obolibrary.org/obo/GO_0098764 meiosis I cell cycle phase The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. http://purl.obolibrary.org/obo/GO_0007135 meiosis II http://purl.obolibrary.org/obo/GO_0061983 meiosis II cell cycle process The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II. http://purl.obolibrary.org/obo/GO_0007136 meiotic prophase II http://purl.obolibrary.org/obo/GO_0051324 prophase The cell cycle phase which is the first stage of meiosis II and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell. http://purl.obolibrary.org/obo/GO_0007137 meiotic metaphase II http://purl.obolibrary.org/obo/GO_0051323 metaphase The cell cycle phase, following prophase II, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis II. http://purl.obolibrary.org/obo/GO_0007138 meiotic anaphase II http://purl.obolibrary.org/obo/GO_0051322 anaphase The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis II. http://purl.obolibrary.org/obo/GO_0007139 meiotic telophase II http://purl.obolibrary.org/obo/GO_0051326 telophase The cell cycle phase which follows anaphase II of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. http://purl.obolibrary.org/obo/GO_0007140 male meiotic nuclear division http://purl.obolibrary.org/obo/GO_0022412 cellular process involved in reproduction in multicellular organism A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline. http://purl.obolibrary.org/obo/GO_0007142 male meiosis II http://purl.obolibrary.org/obo/GO_0007140 male meiotic nuclear division A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline. http://purl.obolibrary.org/obo/GO_0007143 female meiotic nuclear division http://purl.obolibrary.org/obo/GO_0022412 cellular process involved in reproduction in multicellular organism A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline. http://purl.obolibrary.org/obo/GO_0007147 female meiosis II http://purl.obolibrary.org/obo/GO_0007143 female meiotic nuclear division The cell cycle process in which the second meiotic division occurs in the female germline. http://purl.obolibrary.org/obo/GO_0007162 negative regulation of cell adhesion http://purl.obolibrary.org/obo/GO_0030155 regulation of cell adhesion Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion. http://purl.obolibrary.org/obo/GO_0007276 gamete generation http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell. http://purl.obolibrary.org/obo/GO_0007281 germ cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism. http://purl.obolibrary.org/obo/GO_0007283 spermatogenesis http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa. http://purl.obolibrary.org/obo/GO_0007288 sperm axoneme assembly http://purl.obolibrary.org/obo/GO_0022412 cellular process involved in reproduction in multicellular organism The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement. http://purl.obolibrary.org/obo/GO_0007289 spermatid nucleus differentiation http://purl.obolibrary.org/obo/GO_0022412 cellular process involved in reproduction in multicellular organism The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization. http://purl.obolibrary.org/obo/GO_0007292 female gamete generation http://purl.obolibrary.org/obo/GO_0007276 gamete generation Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction. http://purl.obolibrary.org/obo/GO_0007338 single fertilization http://purl.obolibrary.org/obo/GO_0009566 fertilization The union of male and female gametes to form a zygote. http://purl.obolibrary.org/obo/GO_0007346 regulation of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0051726 regulation of cell cycle Any process that modulates the rate or extent of progress through the mitotic cell cycle. http://purl.obolibrary.org/obo/GO_0007399 nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. http://purl.obolibrary.org/obo/GO_0007417 central nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. http://purl.obolibrary.org/obo/GO_0007420 brain development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). http://purl.obolibrary.org/obo/GO_0007568 aging http://purl.obolibrary.org/obo/GO_0032502 developmental process A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700). http://purl.obolibrary.org/obo/GO_0007584 response to nutrient http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus. http://purl.obolibrary.org/obo/GO_0007588 excretion http://purl.obolibrary.org/obo/GO_0003008 system process The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds. http://purl.obolibrary.org/obo/GO_0007596 blood coagulation http://purl.obolibrary.org/obo/GO_0050817 coagulation The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers. http://purl.obolibrary.org/obo/GO_0007599 hemostasis http://purl.obolibrary.org/obo/GO_0050878 regulation of body fluid levels The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part. http://purl.obolibrary.org/obo/GO_0007600 sensory perception http://purl.obolibrary.org/obo/GO_0050877 nervous system process The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_0007601 visual perception http://purl.obolibrary.org/obo/GO_0050953 sensory perception of light stimulus The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image. http://purl.obolibrary.org/obo/GO_0007602 phototransduction http://purl.obolibrary.org/obo/GO_0007165 signal transduction The sequence of reactions within a cell required to convert absorbed photons into a molecular signal. http://purl.obolibrary.org/obo/GO_0007603 phototransduction, visible light http://purl.obolibrary.org/obo/GO_0009584 detection of visible light The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm. http://purl.obolibrary.org/obo/GO_0007604 phototransduction, UV http://purl.obolibrary.org/obo/GO_0034644 cellular response to UV The sequence of reactions within a cell required to convert absorbed photons from UV light into a molecular signal; ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 400 nanometers. http://purl.obolibrary.org/obo/GO_0007605 sensory perception of sound http://purl.obolibrary.org/obo/GO_0050954 sensory perception of mechanical stimulus The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound. http://purl.obolibrary.org/obo/GO_0007606 sensory perception of chemical stimulus http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_0007608 sensory perception of smell http://purl.obolibrary.org/obo/GO_0007606 sensory perception of chemical stimulus The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process. http://purl.obolibrary.org/obo/GO_0007611 learning or memory http://purl.obolibrary.org/obo/GO_0007610 behavior The acquisition and processing of information and/or the storage and retrieval of this information over time. http://purl.obolibrary.org/obo/GO_0007612 learning http://purl.obolibrary.org/obo/GO_0007611 learning or memory Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience. http://purl.obolibrary.org/obo/GO_0007613 memory http://purl.obolibrary.org/obo/GO_0007611 learning or memory The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task). http://purl.obolibrary.org/obo/GO_0007614 short-term memory http://purl.obolibrary.org/obo/GO_0007613 memory The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation. http://purl.obolibrary.org/obo/GO_0007616 long-term memory http://purl.obolibrary.org/obo/GO_0007613 memory The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation. http://purl.obolibrary.org/obo/GO_0007617 mating behavior http://purl.obolibrary.org/obo/GO_0019098 reproductive behavior The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes. http://purl.obolibrary.org/obo/GO_0007618 mating http://purl.obolibrary.org/obo/GO_0044703 multi-organism reproductive process The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes. http://purl.obolibrary.org/obo/GO_0007620 copulation http://purl.obolibrary.org/obo/GO_0007618 mating The act of sexual union between male and female, involving the transfer of sperm. http://purl.obolibrary.org/obo/GO_0007622 rhythmic behavior http://purl.obolibrary.org/obo/GO_0007610 behavior The specific behavior of an organism that recur with measured regularity. http://purl.obolibrary.org/obo/GO_0007626 locomotory behavior http://purl.obolibrary.org/obo/GO_0007610 behavior The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions. http://purl.obolibrary.org/obo/GO_0007632 visual behavior http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The behavior of an organism in response to a visual stimulus. http://purl.obolibrary.org/obo/GO_0007635 chemosensory behavior http://purl.obolibrary.org/obo/GO_0007610 behavior Behavior that is dependent upon the sensation of chemicals. http://purl.obolibrary.org/obo/GO_0008104 protein localization http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization Any process in which a protein is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0008152 metabolic process http://purl.obolibrary.org/obo/GO_0008150 biological_process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. http://purl.obolibrary.org/obo/GO_0008301 DNA binding, bending http://purl.obolibrary.org/obo/GO_0003677 DNA binding The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence. http://purl.obolibrary.org/obo/GO_0008356 asymmetric cell division http://purl.obolibrary.org/obo/GO_0051301 cell division The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity. http://purl.obolibrary.org/obo/GO_0008509 anion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015075 ion transmembrane transporter activity Enables the transfer of a negatively charged ion from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0008641 ubiquitin-like modifier activating enzyme activity http://purl.obolibrary.org/obo/GO_0016877 ligase activity, forming carbon-sulfur bonds Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond. http://purl.obolibrary.org/obo/GO_0009100 glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_1901135 carbohydrate derivative metabolic process The chemical reactions and pathways involving glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0009101 glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_1901566 organonitrogen compound biosynthetic process The chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0009116 nucleoside metabolic process http://purl.obolibrary.org/obo/GO_1901657 glycosyl compound metabolic process The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine). http://purl.obolibrary.org/obo/GO_0009117 nucleotide metabolic process http://purl.obolibrary.org/obo/GO_0006753 nucleoside phosphate metabolic process The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates). http://purl.obolibrary.org/obo/GO_0009152 purine ribonucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0009260 ribonucleotide biosynthetic process The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/GO_0009165 nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_1901293 nucleoside phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates). http://purl.obolibrary.org/obo/GO_0009168 purine ribonucleoside monophosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0009167 purine ribonucleoside monophosphate metabolic process The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009206 purine ribonucleoside triphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0009205 purine ribonucleoside triphosphate metabolic process The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009267 cellular response to starvation http://purl.obolibrary.org/obo/GO_0042594 response to starvation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment. http://purl.obolibrary.org/obo/GO_0009277 fungal-type cell wall http://purl.obolibrary.org/obo/GO_0005618 cell wall A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not cellulose or pectin. Enzymes involved in cell wall biosynthesis are also found in the cell wall. Note that some forms of fungi develop a capsule outside of the cell wall under certain circumstances; this is considered a separate structure. http://purl.obolibrary.org/obo/GO_0009408 response to heat http://purl.obolibrary.org/obo/GO_0009266 response to temperature stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. http://purl.obolibrary.org/obo/GO_0009416 response to light stimulus http://purl.obolibrary.org/obo/GO_0009314 response to radiation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light. http://purl.obolibrary.org/obo/GO_0009566 fertilization http://purl.obolibrary.org/obo/GO_0022414 reproductive process The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). http://purl.obolibrary.org/obo/GO_0009583 detection of light stimulus http://purl.obolibrary.org/obo/GO_0009582 detection of abiotic stimulus The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0009584 detection of visible light http://purl.obolibrary.org/obo/GO_0009583 detection of light stimulus The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm. http://purl.obolibrary.org/obo/GO_0009589 detection of UV http://purl.obolibrary.org/obo/GO_0009411 response to UV The series of events in which an ultraviolet radiation (UV light) stimulus is received and converted into a molecular signal. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus. http://purl.obolibrary.org/obo/GO_0010256 endomembrane system organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system. http://purl.obolibrary.org/obo/GO_0010324 membrane invagination http://purl.obolibrary.org/obo/GO_0061024 membrane organization The infolding of a membrane. http://purl.obolibrary.org/obo/GO_0010469 regulation of signaling receptor activity http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0010564 regulation of cell cycle process http://purl.obolibrary.org/obo/GO_0051726 regulation of cell cycle Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. http://purl.obolibrary.org/obo/GO_0010608 posttranscriptional regulation of gene expression http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript. http://purl.obolibrary.org/obo/GO_0010629 negative regulation of gene expression http://purl.obolibrary.org/obo/GO_0010605 negative regulation of macromolecule metabolic process Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/GO_0010970 transport along microtubule http://purl.obolibrary.org/obo/GO_0099111 microtubule-based transport The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity. http://purl.obolibrary.org/obo/GO_0012505 endomembrane system http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. http://purl.obolibrary.org/obo/GO_0015031 protein transport http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015075 ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of an ion from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0015893 drug transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015939 pantothenate metabolic process http://purl.obolibrary.org/obo/GO_0043603 cellular amide metabolic process The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods. http://purl.obolibrary.org/obo/GO_0016020 membrane http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. http://purl.obolibrary.org/obo/GO_0016043 cellular component organization http://purl.obolibrary.org/obo/GO_0071840 cellular component organization or biogenesis A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. http://purl.obolibrary.org/obo/GO_0016192 vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0009987 cellular process A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. http://purl.obolibrary.org/obo/GO_0016310 phosphorylation http://purl.obolibrary.org/obo/GO_0006796 phosphate-containing compound metabolic process The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. http://purl.obolibrary.org/obo/GO_0016458 gene silencing http://purl.obolibrary.org/obo/GO_0009987 cellular process Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression. http://purl.obolibrary.org/obo/GO_0016482 cytosolic transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of substances or organelles within the cytosol. http://purl.obolibrary.org/obo/GO_0019098 reproductive behavior http://purl.obolibrary.org/obo/GO_0007610 behavior The specific behavior of an organism that is associated with reproduction. http://purl.obolibrary.org/obo/GO_0019219 regulation of nucleobase-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0051171 regulation of nitrogen compound metabolic process Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0019220 regulation of phosphate metabolic process http://purl.obolibrary.org/obo/GO_0051174 regulation of phosphorus metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates. http://purl.obolibrary.org/obo/GO_0019538 protein metabolic process http://purl.obolibrary.org/obo/GO_1901564 organonitrogen compound metabolic process The chemical reactions and pathways involving a protein. Includes protein modification. http://purl.obolibrary.org/obo/GO_0019637 organophosphate metabolic process http://purl.obolibrary.org/obo/GO_0071704 organic substance metabolic process The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound. http://purl.obolibrary.org/obo/GO_0019693 ribose phosphate metabolic process http://purl.obolibrary.org/obo/GO_1901135 carbohydrate derivative metabolic process The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar. http://purl.obolibrary.org/obo/GO_0019725 cellular homeostasis http://purl.obolibrary.org/obo/GO_0042592 homeostatic process Any process involved in the maintenance of an internal steady state at the level of the cell. http://purl.obolibrary.org/obo/GO_0019747 regulation of isoprenoid metabolic process http://purl.obolibrary.org/obo/GO_0019216 regulation of lipid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids. http://purl.obolibrary.org/obo/GO_0019752 carboxylic acid metabolic process http://purl.obolibrary.org/obo/GO_0043436 oxoacid metabolic process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/GO_0019787 ubiquitin-like protein transferase activity http://purl.obolibrary.org/obo/GO_0140096 catalytic activity, acting on a protein Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y --> Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein. http://purl.obolibrary.org/obo/GO_0021700 developmental maturation http://purl.obolibrary.org/obo/GO_0032502 developmental process A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0022411 cellular component disassembly http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A cellular process that results in the breakdown of a cellular component. http://purl.obolibrary.org/obo/GO_0022610 biological adhesion http://purl.obolibrary.org/obo/GO_0008150 biological_process The attachment of a cell or organism to a substrate, another cell, or other organism. Biological adhesion includes intracellular attachment between membrane regions. http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0005215 transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0030003 cellular cation homeostasis http://purl.obolibrary.org/obo/GO_0055080 cation homeostasis Any process involved in the maintenance of an internal steady state of cations at the level of a cell. http://purl.obolibrary.org/obo/GO_0030031 cell projection assembly http://purl.obolibrary.org/obo/GO_0030030 cell projection organization Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon. http://purl.obolibrary.org/obo/GO_0030054 cell junction http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella. http://purl.obolibrary.org/obo/GO_0030135 coated vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins. http://purl.obolibrary.org/obo/GO_0030262 apoptotic nuclear changes http://purl.obolibrary.org/obo/GO_0006921 cellular component disassembly involved in execution phase of apoptosis Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space. http://purl.obolibrary.org/obo/GO_0030317 flagellated sperm motility http://purl.obolibrary.org/obo/GO_0060285 cilium-dependent cell motility Any process involved in the controlled movement of a flagellated sperm cell. http://purl.obolibrary.org/obo/GO_0030990 intraciliary transport particle http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules. http://purl.obolibrary.org/obo/GO_0031012 extracellular matrix http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues. http://purl.obolibrary.org/obo/GO_0031345 negative regulation of cell projection organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. http://purl.obolibrary.org/obo/GO_0031967 organelle envelope http://purl.obolibrary.org/obo/GO_0031975 envelope A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes. http://purl.obolibrary.org/obo/GO_0031970 organelle envelope lumen http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen The region between the inner and outer lipid bilayers of an organelle envelope. http://purl.obolibrary.org/obo/GO_0031974 membrane-enclosed lumen http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen. http://purl.obolibrary.org/obo/GO_0032042 mitochondrial DNA metabolic process http://purl.obolibrary.org/obo/GO_0006259 DNA metabolic process The chemical reactions and pathways involving mitochondrial DNA. http://purl.obolibrary.org/obo/GO_0032259 methylation http://purl.obolibrary.org/obo/GO_0008152 metabolic process The process in which a methyl group is covalently attached to a molecule. http://purl.obolibrary.org/obo/GO_0032268 regulation of cellular protein metabolic process http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. http://purl.obolibrary.org/obo/GO_0032787 monocarboxylic acid metabolic process http://purl.obolibrary.org/obo/GO_0019752 carboxylic acid metabolic process The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-). http://purl.obolibrary.org/obo/GO_0033013 tetrapyrrole metabolic process http://purl.obolibrary.org/obo/GO_1901564 organonitrogen compound metabolic process The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which a macromolecule is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0033045 regulation of sister chromatid segregation http://purl.obolibrary.org/obo/GO_0051983 regulation of chromosome segregation Any process that modulates the frequency, rate or extent of sister chromatid segregation. http://purl.obolibrary.org/obo/GO_0033673 negative regulation of kinase activity http://purl.obolibrary.org/obo/GO_0051348 negative regulation of transferase activity Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. http://purl.obolibrary.org/obo/GO_0034641 cellular nitrogen compound metabolic process http://purl.obolibrary.org/obo/GO_0044237 cellular metabolic process The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells. http://purl.obolibrary.org/obo/GO_0034644 cellular response to UV http://purl.obolibrary.org/obo/GO_0071482 cellular response to light stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. http://purl.obolibrary.org/obo/GO_0034645 cellular macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells. http://purl.obolibrary.org/obo/GO_0034765 regulation of ion transmembrane transport http://purl.obolibrary.org/obo/GO_0043269 regulation of ion transport Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0035082 axoneme assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. http://purl.obolibrary.org/obo/GO_0035239 tube morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. http://purl.obolibrary.org/obo/GO_0035295 tube development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts. http://purl.obolibrary.org/obo/GO_0036211 protein modification process http://purl.obolibrary.org/obo/GO_0043412 macromolecule modification The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). http://purl.obolibrary.org/obo/GO_0040029 regulation of gene expression, epigenetic http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence. http://purl.obolibrary.org/obo/GO_0042278 purine nucleoside metabolic process http://purl.obolibrary.org/obo/GO_0072521 purine-containing compound metabolic process The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). http://purl.obolibrary.org/obo/GO_0042558 pteridine-containing compound metabolic process http://purl.obolibrary.org/obo/GO_1901564 organonitrogen compound metabolic process The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid. http://purl.obolibrary.org/obo/GO_0042723 thiamine-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0017144 drug metabolic process The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it. http://purl.obolibrary.org/obo/GO_0042886 amide transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0042887 amide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0043005 neuron projection http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A prolongation or process extending from a nerve cell, e.g. an axon or dendrite. http://purl.obolibrary.org/obo/GO_0043066 negative regulation of apoptotic process http://purl.obolibrary.org/obo/GO_0043069 negative regulation of programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0043085 positive regulation of catalytic activity http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity Any process that activates or increases the activity of an enzyme. http://purl.obolibrary.org/obo/GO_0043086 negative regulation of catalytic activity http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity Any process that stops or reduces the activity of an enzyme. http://purl.obolibrary.org/obo/GO_0043170 macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0071704 organic substance metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle http://purl.obolibrary.org/obo/GO_0043229 intracellular organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0043412 macromolecule modification http://purl.obolibrary.org/obo/GO_0043170 macromolecule metabolic process The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. http://purl.obolibrary.org/obo/GO_0043413 macromolecule glycosylation http://purl.obolibrary.org/obo/GO_0070085 glycosylation The covalent attachment of a glycosyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule. http://purl.obolibrary.org/obo/GO_0043648 dicarboxylic acid metabolic process http://purl.obolibrary.org/obo/GO_0019752 carboxylic acid metabolic process The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/GO_0044070 regulation of anion transport http://purl.obolibrary.org/obo/GO_0043269 regulation of ion transport Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0044087 regulation of cellular component biogenesis http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. http://purl.obolibrary.org/obo/GO_0044248 cellular catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. http://purl.obolibrary.org/obo/GO_0044249 cellular biosynthetic process http://purl.obolibrary.org/obo/GO_0044237 cellular metabolic process The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. http://purl.obolibrary.org/obo/GO_0044255 cellular lipid metabolic process http://purl.obolibrary.org/obo/GO_0044237 cellular metabolic process The chemical reactions and pathways involving lipids, as carried out by individual cells. http://purl.obolibrary.org/obo/GO_0044260 cellular macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0044237 cellular metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. http://purl.obolibrary.org/obo/GO_0044267 cellular protein metabolic process http://purl.obolibrary.org/obo/GO_0044260 cellular macromolecule metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification. http://purl.obolibrary.org/obo/GO_0044281 small molecule metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule. http://purl.obolibrary.org/obo/GO_0044456 obsolete synapse part http://purl.obolibrary.org/obo/GO_0044464 obsolete cell part OBSOLETE. Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. http://purl.obolibrary.org/obo/GO_0044464 obsolete cell part http://purl.obolibrary.org/obo/CARO_0000014 cell part OBSOLETE. Any constituent part of a cell, the basic structural and functional unit of all organisms. http://purl.obolibrary.org/obo/GO_0044706 multi-multicellular organism process http://purl.obolibrary.org/obo/GO_0051704 multi-organism process A multicellular organism process which involves another multicellular organism of the same or different species. http://purl.obolibrary.org/obo/GO_0044728 DNA methylation or demethylation http://purl.obolibrary.org/obo/GO_0006304 DNA modification The process of adding or removing a methyl group from one or more nucleotides within an DNA molecule. http://purl.obolibrary.org/obo/GO_0044853 plasma membrane raft http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region A membrane raft that is part of the plasma membrane. http://purl.obolibrary.org/obo/GO_0045132 meiotic chromosome segregation http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0045596 negative regulation of cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation. http://purl.obolibrary.org/obo/GO_0045930 negative regulation of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0045786 negative regulation of cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle. http://purl.obolibrary.org/obo/GO_0046034 ATP metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator. http://purl.obolibrary.org/obo/GO_0046129 purine ribonucleoside biosynthetic process http://purl.obolibrary.org/obo/GO_0042455 ribonucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule. http://purl.obolibrary.org/obo/GO_0046390 ribose phosphate biosynthetic process http://purl.obolibrary.org/obo/GO_1901137 carbohydrate derivative biosynthetic process The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar. http://purl.obolibrary.org/obo/GO_0046907 intracellular transport http://purl.obolibrary.org/obo/GO_0051641 cellular localization The directed movement of substances within a cell. http://purl.obolibrary.org/obo/GO_0046942 carboxylic acid transport http://purl.obolibrary.org/obo/GO_0015849 organic acid transport The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/GO_0046943 carboxylic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015318 inorganic molecular entity transmembrane transporter activity Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/GO_0048193 Golgi vesicle transport http://purl.obolibrary.org/obo/GO_0016192 vesicle-mediated transport The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles. http://purl.obolibrary.org/obo/GO_0048232 male gamete generation http://purl.obolibrary.org/obo/GO_0007276 gamete generation Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction. http://purl.obolibrary.org/obo/GO_0048477 oogenesis http://purl.obolibrary.org/obo/GO_0007292 female gamete generation The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0048511 rhythmic process http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism. http://purl.obolibrary.org/obo/GO_0048512 circadian behavior http://purl.obolibrary.org/obo/GO_0007623 circadian rhythm The specific behavior of an organism that recurs with a regularity of approximately 24 hours. http://purl.obolibrary.org/obo/GO_0048515 spermatid differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0048523 negative regulation of cellular process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process http://purl.obolibrary.org/obo/GO_0022414 reproductive process The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs. http://purl.obolibrary.org/obo/GO_0050768 negative regulation of neurogenesis http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system. http://purl.obolibrary.org/obo/GO_0050801 ion homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis Any process involved in the maintenance of an internal steady state of ions within an organism or cell. http://purl.obolibrary.org/obo/GO_0050817 coagulation http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process in which a fluid solution, or part of it, changes into a solid or semisolid mass. http://purl.obolibrary.org/obo/GO_0050890 cognition http://purl.obolibrary.org/obo/GO_0050877 nervous system process The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory. http://purl.obolibrary.org/obo/GO_0050896 response to stimulus http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. http://purl.obolibrary.org/obo/GO_0050953 sensory perception of light stimulus http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_0050954 sensory perception of mechanical stimulus http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_0051053 negative regulation of DNA metabolic process http://purl.obolibrary.org/obo/GO_0045934 negative regulation of nucleobase-containing compound metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA. http://purl.obolibrary.org/obo/GO_0051181 cofactor transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of a cofactor into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A cofactor is a substance that is required for the activity of an enzyme or other protein. http://purl.obolibrary.org/obo/GO_0051186 cofactor metabolic process http://purl.obolibrary.org/obo/GO_0044237 cellular metabolic process The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate. http://purl.obolibrary.org/obo/GO_0051196 regulation of coenzyme metabolic process http://purl.obolibrary.org/obo/GO_0051193 regulation of cofactor metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme. http://purl.obolibrary.org/obo/GO_0051225 spindle assembly http://purl.obolibrary.org/obo/GO_0070925 organelle assembly The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart. http://purl.obolibrary.org/obo/GO_0051234 establishment of localization http://purl.obolibrary.org/obo/GO_0051179 localization Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. http://purl.obolibrary.org/obo/GO_0051427 hormone receptor binding http://purl.obolibrary.org/obo/GO_0005102 signaling receptor binding Interacting selectively and non-covalently with a receptor for hormones. http://purl.obolibrary.org/obo/GO_0051649 establishment of localization in cell http://purl.obolibrary.org/obo/GO_0051234 establishment of localization Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. http://purl.obolibrary.org/obo/GO_0051650 establishment of vesicle localization http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of a vesicle to a specific location. http://purl.obolibrary.org/obo/GO_0051716 cellular response to stimulus http://purl.obolibrary.org/obo/GO_0009987 cellular process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. http://purl.obolibrary.org/obo/GO_0051783 regulation of nuclear division http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. http://purl.obolibrary.org/obo/GO_0055065 metal ion homeostasis http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis Any process involved in the maintenance of an internal steady state of metal ions within an organism or cell. http://purl.obolibrary.org/obo/GO_0055069 zinc ion homeostasis http://purl.obolibrary.org/obo/GO_0072507 divalent inorganic cation homeostasis Any process involved in the maintenance of an internal steady state of zinc ions within an organism or cell. http://purl.obolibrary.org/obo/GO_0055074 calcium ion homeostasis http://purl.obolibrary.org/obo/GO_0072507 divalent inorganic cation homeostasis Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell. http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport http://purl.obolibrary.org/obo/GO_0009987 cellular process The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0055086 nucleobase-containing small molecule metabolic process http://purl.obolibrary.org/obo/GO_0044281 small molecule metabolic process The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide. http://purl.obolibrary.org/obo/GO_0060089 molecular transducer activity http://purl.obolibrary.org/obo/GO_0003674 molecular_function A compound molecular function in which an effector function is controlled by one or more regulatory components. http://purl.obolibrary.org/obo/GO_0060281 regulation of oocyte development http://purl.obolibrary.org/obo/GO_1905879 regulation of oogenesis Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0060322 head development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body. http://purl.obolibrary.org/obo/GO_0061024 membrane organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex subunit organization The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex. http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen http://purl.obolibrary.org/obo/GO_0043233 organelle lumen An organelle lumen that is part of an intracellular organelle. http://purl.obolibrary.org/obo/GO_0070192 chromosome organization involved in meiotic cell cycle http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process A process of chromosome organization that is involved in a meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0071103 DNA conformation change http://purl.obolibrary.org/obo/GO_0051276 chromosome organization A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule. http://purl.obolibrary.org/obo/GO_0071702 organic substance transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon. http://purl.obolibrary.org/obo/GO_0071704 organic substance metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0071944 cell periphery http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures. http://purl.obolibrary.org/obo/GO_0072359 circulatory system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. http://purl.obolibrary.org/obo/GO_0072503 cellular divalent inorganic cation homeostasis http://purl.obolibrary.org/obo/GO_0072507 divalent inorganic cation homeostasis Any process involved in the maintenance of an internal steady state of divalent cations at the level of a cell. http://purl.obolibrary.org/obo/GO_0072521 purine-containing compound metabolic process http://purl.obolibrary.org/obo/GO_1901564 organonitrogen compound metabolic process The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof. http://purl.obolibrary.org/obo/GO_0072522 purine-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_1901566 organonitrogen compound biosynthetic process The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof. http://purl.obolibrary.org/obo/GO_0072527 pyrimidine-containing compound metabolic process http://purl.obolibrary.org/obo/GO_1901564 organonitrogen compound metabolic process The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof. http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. http://purl.obolibrary.org/obo/GO_0090304 nucleic acid metabolic process http://purl.obolibrary.org/obo/GO_0043170 macromolecule metabolic process Any cellular metabolic process involving nucleic acids. http://purl.obolibrary.org/obo/GO_0090306 spindle assembly involved in meiosis http://purl.obolibrary.org/obo/GO_0000212 meiotic spindle organization The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis. http://purl.obolibrary.org/obo/GO_0090407 organophosphate biosynthetic process http://purl.obolibrary.org/obo/GO_1901576 organic substance biosynthetic process The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose. http://purl.obolibrary.org/obo/GO_0097014 ciliary plasm http://purl.obolibrary.org/obo/GO_0032838 plasma membrane bounded cell projection cytoplasm All of the contents of a cilium, excluding the plasma membrane surrounding the cilium. http://purl.obolibrary.org/obo/GO_0097194 execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0009987 cellular process A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. http://purl.obolibrary.org/obo/GO_0098765 meiosis II cell cycle phase http://purl.obolibrary.org/obo/GO_0098762 meiotic cell cycle phase A meiotic cell cycle phase that occurs after meiosis I (the first meiotic nuclear division). http://purl.obolibrary.org/obo/GO_0098772 molecular function regulator http://purl.obolibrary.org/obo/GO_0003674 molecular_function A molecular function that modulates the activity of a gene product or complex. Examples include enzyme regulators and channel regulators. http://purl.obolibrary.org/obo/GO_0098791 Golgi subcompartment http://purl.obolibrary.org/obo/GO_0031984 organelle subcompartment A compartment that consists of a lumen and an enclosing membrane, and is part of the Golgi Apparatus. http://purl.obolibrary.org/obo/GO_0098798 mitochondrial protein complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A protein complex that is part of a mitochondrion. http://purl.obolibrary.org/obo/GO_0098805 whole membrane http://purl.obolibrary.org/obo/GO_0016020 membrane Any lipid bilayer that completely encloses some structure, and all the proteins embedded in it or attached to it. Examples include the plasma membrane and most organelle membranes. http://purl.obolibrary.org/obo/GO_0099568 cytoplasmic region http://purl.obolibrary.org/obo/GO_0005737 cytoplasm Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm" http://purl.obolibrary.org/obo/GO_0099643 signal release from synapse http://purl.obolibrary.org/obo/GO_0023061 signal release Any signal release from a synapse. http://purl.obolibrary.org/obo/GO_1901135 carbohydrate derivative metabolic process http://purl.obolibrary.org/obo/GO_0071704 organic substance metabolic process The chemical reactions and pathways involving carbohydrate derivative. http://purl.obolibrary.org/obo/GO_1901137 carbohydrate derivative biosynthetic process http://purl.obolibrary.org/obo/GO_1901576 organic substance biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrate derivative. http://purl.obolibrary.org/obo/GO_1901576 organic substance biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon. http://purl.obolibrary.org/obo/GO_1901615 organic hydroxy compound metabolic process http://purl.obolibrary.org/obo/GO_0071704 organic substance metabolic process The chemical reactions and pathways involving organic hydroxy compound. http://purl.obolibrary.org/obo/GO_1902850 microtubule cytoskeleton organization involved in mitosis http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process Any microtubule cytoskeleton organization that is involved in mitosis. http://purl.obolibrary.org/obo/GO_1903429 regulation of cell maturation http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of cell maturation. http://purl.obolibrary.org/obo/GO_1903664 regulation of asexual reproduction http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of asexual reproduction. http://purl.obolibrary.org/obo/GO_1903825 organic acid transmembrane transport http://purl.obolibrary.org/obo/GO_0015849 organic acid transport The process in which an organic acid is transported across a membrane. http://purl.obolibrary.org/obo/GO_2000112 regulation of cellular macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0031326 regulation of cellular biosynthetic process Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process. http://purl.obolibrary.org/obo/GO_2000113 negative regulation of cellular macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0031327 negative regulation of cellular biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of cellular macromolecule biosynthetic process. http://purl.obolibrary.org/obo/GO_2000272 negative regulation of signaling receptor activity http://purl.obolibrary.org/obo/GO_0044092 negative regulation of molecular function Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity. http://purl.obolibrary.org/obo/GO_2001020 regulation of response to DNA damage stimulus http://purl.obolibrary.org/obo/GO_0080135 regulation of cellular response to stress Any process that modulates the frequency, rate or extent of response to DNA damage stimulus. http://purl.obolibrary.org/obo/GO_0045833 negative regulation of lipid metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids. http://purl.obolibrary.org/obo/GO_0045834 positive regulation of lipid metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids. http://purl.obolibrary.org/obo/GO_0045931 positive regulation of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0045787 positive regulation of cell cycle Any process that activates or increases the rate or extent of progression through the mitotic cell cycle. http://purl.obolibrary.org/obo/GO_0045938 positive regulation of circadian sleep/wake cycle, sleep http://purl.obolibrary.org/obo/GO_0048520 positive regulation of behavior Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals. http://purl.obolibrary.org/obo/GO_0045978 negative regulation of nucleoside metabolic process http://purl.obolibrary.org/obo/GO_0045934 negative regulation of nucleobase-containing compound metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides. http://purl.obolibrary.org/obo/GO_0045979 positive regulation of nucleoside metabolic process http://purl.obolibrary.org/obo/GO_0009118 regulation of nucleoside metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides. http://purl.obolibrary.org/obo/GO_0045992 negative regulation of embryonic development http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development. http://purl.obolibrary.org/obo/GO_0046005 positive regulation of circadian sleep/wake cycle, REM sleep http://purl.obolibrary.org/obo/GO_0042320 regulation of circadian sleep/wake cycle, REM sleep Any process that activates or increases the duration or quality of rapid eye movement (REM) sleep. http://purl.obolibrary.org/obo/GO_0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep http://purl.obolibrary.org/obo/GO_0045188 regulation of circadian sleep/wake cycle, non-REM sleep Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep. http://purl.obolibrary.org/obo/GO_0046136 positive regulation of vitamin metabolic process http://purl.obolibrary.org/obo/GO_0030656 regulation of vitamin metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. http://purl.obolibrary.org/obo/GO_0046655 folic acid metabolic process http://purl.obolibrary.org/obo/GO_0017144 drug metabolic process The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines. http://purl.obolibrary.org/obo/GO_0046956 positive phototaxis http://purl.obolibrary.org/obo/GO_0042331 phototaxis The directed movement of a cell or organism towards a source of light. http://purl.obolibrary.org/obo/GO_0046957 negative phototaxis http://purl.obolibrary.org/obo/GO_0042331 phototaxis The directed movement of a cell or organism away from a source of light. http://purl.obolibrary.org/obo/GO_0046958 nonassociative learning http://purl.obolibrary.org/obo/GO_0007612 learning A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment. http://purl.obolibrary.org/obo/GO_0046959 habituation http://purl.obolibrary.org/obo/GO_0046958 nonassociative learning A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented. http://purl.obolibrary.org/obo/GO_0046960 sensitization http://purl.obolibrary.org/obo/GO_0046958 nonassociative learning An increased in a behavioral response to a repeated stimulus. For example, a shock to the tail of the marine snail Aplysia, to which the snail responds by withdrawing its gill, will result in increased gill withdrawal the next time the skin is touched. http://purl.obolibrary.org/obo/GO_0048046 apoplast http://purl.obolibrary.org/obo/GO_0005576 extracellular region The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it. http://purl.obolibrary.org/obo/GO_0048144 fibroblast proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population. http://purl.obolibrary.org/obo/GO_0048145 regulation of fibroblast proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells. http://purl.obolibrary.org/obo/GO_0048146 positive regulation of fibroblast proliferation http://purl.obolibrary.org/obo/GO_0008284 positive regulation of cell population proliferation Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells. http://purl.obolibrary.org/obo/GO_0048147 negative regulation of fibroblast proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells. http://purl.obolibrary.org/obo/GO_0048237 rough endoplasmic reticulum lumen http://purl.obolibrary.org/obo/GO_0005788 endoplasmic reticulum lumen The volume enclosed by the membranes of the rough endoplasmic reticulum. http://purl.obolibrary.org/obo/GO_0048238 smooth endoplasmic reticulum lumen http://purl.obolibrary.org/obo/GO_0005788 endoplasmic reticulum lumen The volume enclosed by the membranes of the smooth endoplasmic reticulum. http://purl.obolibrary.org/obo/GO_0050708 regulation of protein secretion http://purl.obolibrary.org/obo/GO_0051223 regulation of protein transport Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell. http://purl.obolibrary.org/obo/GO_0050709 negative regulation of protein secretion http://purl.obolibrary.org/obo/GO_0051224 negative regulation of protein transport Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell. http://purl.obolibrary.org/obo/GO_0050906 detection of stimulus involved in sensory perception http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0050908 detection of light stimulus involved in visual perception http://purl.obolibrary.org/obo/GO_0050962 detection of light stimulus involved in sensory perception The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0050909 sensory perception of taste http://purl.obolibrary.org/obo/GO_0007606 sensory perception of chemical stimulus The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process. http://purl.obolibrary.org/obo/GO_0050962 detection of light stimulus involved in sensory perception http://purl.obolibrary.org/obo/GO_0050906 detection of stimulus involved in sensory perception The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light. http://purl.obolibrary.org/obo/GO_0051193 regulation of cofactor metabolic process http://purl.obolibrary.org/obo/GO_0031323 regulation of cellular metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a cofactor. http://purl.obolibrary.org/obo/GO_0051194 positive regulation of cofactor metabolic process http://purl.obolibrary.org/obo/GO_0031325 positive regulation of cellular metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a cofactor. http://purl.obolibrary.org/obo/GO_0051195 negative regulation of cofactor metabolic process http://purl.obolibrary.org/obo/GO_0031324 negative regulation of cellular metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a cofactor. http://purl.obolibrary.org/obo/GO_0051197 positive regulation of coenzyme metabolic process http://purl.obolibrary.org/obo/GO_0051194 positive regulation of cofactor metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme. http://purl.obolibrary.org/obo/GO_0051198 negative regulation of coenzyme metabolic process http://purl.obolibrary.org/obo/GO_0051195 negative regulation of cofactor metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme. http://purl.obolibrary.org/obo/GO_0051232 meiotic spindle elongation http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process The lengthening of the distance between poles of the spindle during a meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051245 negative regulation of cellular defense response http://purl.obolibrary.org/obo/GO_0010185 regulation of cellular defense response Any process that stops, prevents, or reduces the rate of the cellular defense response. http://purl.obolibrary.org/obo/GO_0051270 regulation of cellular component movement http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of the movement of a cellular component. http://purl.obolibrary.org/obo/GO_0051325 interphase http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs. http://purl.obolibrary.org/obo/GO_0051327 meiotic M phase http://purl.obolibrary.org/obo/GO_0000279 M phase A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051330 meiotic G1 phase http://purl.obolibrary.org/obo/GO_0051318 G1 phase The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by meiosis and the beginning of DNA synthesis. http://purl.obolibrary.org/obo/GO_0051331 meiotic G2 phase http://purl.obolibrary.org/obo/GO_0051319 G2 phase The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by meiosis. http://purl.obolibrary.org/obo/GO_0051332 meiotic S phase http://purl.obolibrary.org/obo/GO_0051320 S phase The cell cycle phase, following G1, during which DNA synthesis takes place as part of a meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051384 response to glucocorticoid http://purl.obolibrary.org/obo/GO_0031960 response to corticosteroid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. http://purl.obolibrary.org/obo/GO_0051560 mitochondrial calcium ion homeostasis http://purl.obolibrary.org/obo/GO_0006874 cellular calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings. http://purl.obolibrary.org/obo/GO_0051563 smooth endoplasmic reticulum calcium ion homeostasis http://purl.obolibrary.org/obo/GO_0032469 endoplasmic reticulum calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions within the smooth endoplasmic reticulum of a cell or between the smooth endoplasmic reticulum and its surroundings. http://purl.obolibrary.org/obo/GO_0051641 cellular localization http://purl.obolibrary.org/obo/GO_0051179 localization A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane. http://purl.obolibrary.org/obo/GO_0051646 mitochondrion localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0051709 regulation of killing of cells of other organism http://purl.obolibrary.org/obo/GO_0031341 regulation of cell killing Any process that modulates the frequency, rate or extent of the killing by an organism of cells in another organism. http://purl.obolibrary.org/obo/GO_0051711 negative regulation of killing of cells of other organism http://purl.obolibrary.org/obo/GO_0031342 negative regulation of cell killing Any process that stops, prevents, or reduces the frequency, rate or extent of the killing by an organism of cells in another organism. http://purl.obolibrary.org/obo/GO_0051712 positive regulation of killing of cells of other organism http://purl.obolibrary.org/obo/GO_0031343 positive regulation of cell killing Any process that activates or increases the frequency, rate or extent of the killing by an organism of cells in another organism. http://purl.obolibrary.org/obo/GO_0051784 negative regulation of nuclear division http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. http://purl.obolibrary.org/obo/GO_0051785 positive regulation of nuclear division http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. http://purl.obolibrary.org/obo/GO_0051931 regulation of sensory perception http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. http://purl.obolibrary.org/obo/GO_0051984 positive regulation of chromosome segregation http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/GO_0052128 positive energy taxis http://purl.obolibrary.org/obo/GO_0009453 energy taxis The directed movement of a motile cell or organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. http://purl.obolibrary.org/obo/GO_0052129 negative energy taxis http://purl.obolibrary.org/obo/GO_0009453 energy taxis The directed movement of a motile cell or organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. http://purl.obolibrary.org/obo/GO_0060282 positive regulation of oocyte development http://purl.obolibrary.org/obo/GO_1905881 positive regulation of oogenesis Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0060283 negative regulation of oocyte development http://purl.obolibrary.org/obo/GO_1905880 negative regulation of oogenesis Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0065007 biological regulation http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process that modulates a measurable attribute of any biological process, quality or function. http://purl.obolibrary.org/obo/GO_0070201 regulation of establishment of protein localization http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location. http://purl.obolibrary.org/obo/GO_0090307 mitotic spindle assembly http://purl.obolibrary.org/obo/GO_0007052 mitotic spindle organization Mitotic bipolar spindle assembly begins with spindle microtubule nucleation from the separated spindle pole body, includes spindle elongation during prometaphase, and is complete when all kinetochores are stably attached the spindle, and the spindle assembly checkpoint is satisfied. http://purl.obolibrary.org/obo/GO_0098762 meiotic cell cycle phase http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. http://purl.obolibrary.org/obo/GO_1902680 positive regulation of RNA biosynthetic process http://purl.obolibrary.org/obo/GO_2001141 regulation of RNA biosynthetic process Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process. http://purl.obolibrary.org/obo/GO_1903034 regulation of response to wounding http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of response to wounding. http://purl.obolibrary.org/obo/GO_1903035 negative regulation of response to wounding http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding. http://purl.obolibrary.org/obo/GO_1903036 positive regulation of response to wounding http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus Any process that activates or increases the frequency, rate or extent of response to wounding. http://purl.obolibrary.org/obo/GO_1903416 response to glycoside http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoside stimulus. http://purl.obolibrary.org/obo/GO_1903508 positive regulation of nucleic acid-templated transcription http://purl.obolibrary.org/obo/GO_1903506 regulation of nucleic acid-templated transcription Any process that activates or increases the frequency, rate or extent of nucleic acid-templated transcription. http://purl.obolibrary.org/obo/GO_1903579 negative regulation of ATP metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of ATP metabolic process. http://purl.obolibrary.org/obo/GO_1903580 positive regulation of ATP metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of ATP metabolic process. http://purl.obolibrary.org/obo/GO_1904950 negative regulation of establishment of protein localization http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization. http://purl.obolibrary.org/obo/GO_1904951 positive regulation of establishment of protein localization http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates or increases the frequency, rate or extent of establishment of protein localization. http://purl.obolibrary.org/obo/GO_1903999 negative regulation of eating behavior http://purl.obolibrary.org/obo/GO_1903998 regulation of eating behavior Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior. http://purl.obolibrary.org/obo/GO_1904000 positive regulation of eating behavior http://purl.obolibrary.org/obo/GO_1903998 regulation of eating behavior Any process that activates or increases the frequency, rate or extent of eating behavior. http://purl.obolibrary.org/obo/GO_1904057 negative regulation of sensory perception of pain http://purl.obolibrary.org/obo/GO_0051930 regulation of sensory perception of pain Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain. http://purl.obolibrary.org/obo/GO_1904058 positive regulation of sensory perception of pain http://purl.obolibrary.org/obo/GO_0051930 regulation of sensory perception of pain Any process that activates or increases the frequency, rate or extent of sensory perception of pain. http://purl.obolibrary.org/obo/GO_1904059 regulation of locomotor rhythm http://purl.obolibrary.org/obo/GO_0042752 regulation of circadian rhythm Any process that modulates the frequency, rate or extent of locomotor rhythm. http://purl.obolibrary.org/obo/GO_1904060 negative regulation of locomotor rhythm http://purl.obolibrary.org/obo/GO_0042754 negative regulation of circadian rhythm Any process that stops, prevents or reduces the frequency, rate or extent of locomotor rhythm. http://purl.obolibrary.org/obo/GO_1904061 positive regulation of locomotor rhythm http://purl.obolibrary.org/obo/GO_0048520 positive regulation of behavior Any process that activates or increases the frequency, rate or extent of locomotor rhythm. http://purl.obolibrary.org/obo/GO_1904068 G protein-coupled receptor signaling pathway involved in social behavior http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway Any G protein-coupled receptor signaling pathway that is involved in social behavior. http://purl.obolibrary.org/obo/GO_1904081 positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation http://purl.obolibrary.org/obo/GO_0045944 positive regulation of transcription by RNA polymerase II Any positive regulation of transcription from RNA polymerase II promoter that is involved in neuron differentiation. http://purl.obolibrary.org/obo/GO_1904092 regulation of autophagic cell death http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death Any process that modulates the frequency, rate or extent of autophagic cell death. http://purl.obolibrary.org/obo/GO_1904093 negative regulation of autophagic cell death http://purl.obolibrary.org/obo/GO_0043069 negative regulation of programmed cell death Any process that stops, prevents or reduces the frequency, rate or extent of autophagic cell death. http://purl.obolibrary.org/obo/GO_1904094 positive regulation of autophagic cell death http://purl.obolibrary.org/obo/GO_0043068 positive regulation of programmed cell death Any process that activates or increases the frequency, rate or extent of autophagic cell death. http://purl.obolibrary.org/obo/GO_1904170 regulation of bleb assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that modulates the frequency, rate or extent of bleb assembly. http://purl.obolibrary.org/obo/GO_1904171 negative regulation of bleb assembly http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly. http://purl.obolibrary.org/obo/GO_1904172 positive regulation of bleb assembly http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of bleb assembly. http://purl.obolibrary.org/obo/GO_1904409 regulation of secretory granule organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of secretory granule organization. http://purl.obolibrary.org/obo/GO_1904410 negative regulation of secretory granule organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization. http://purl.obolibrary.org/obo/GO_1904411 positive regulation of secretory granule organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of secretory granule organization. http://purl.obolibrary.org/obo/GO_1904660 regulation of sensory perception of bitter taste http://purl.obolibrary.org/obo/GO_0051931 regulation of sensory perception Any process that modulates the frequency, rate or extent of sensory perception of bitter taste. http://purl.obolibrary.org/obo/GO_1904661 negative regulation of sensory perception of bitter taste http://purl.obolibrary.org/obo/GO_0031645 negative regulation of nervous system process Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of bitter taste. http://purl.obolibrary.org/obo/GO_1904662 positive regulation of sensory perception of bitter taste http://purl.obolibrary.org/obo/GO_0031646 positive regulation of nervous system process Any process that activates or increases the frequency, rate or extent of sensory perception of bitter taste. http://purl.obolibrary.org/obo/GO_1904675 regulation of somatic stem cell division http://purl.obolibrary.org/obo/GO_2000035 regulation of stem cell division Any process that modulates the frequency, rate or extent of somatic stem cell division. http://purl.obolibrary.org/obo/GO_1904676 negative regulation of somatic stem cell division http://purl.obolibrary.org/obo/GO_0051782 negative regulation of cell division Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division. http://purl.obolibrary.org/obo/GO_1904677 positive regulation of somatic stem cell division http://purl.obolibrary.org/obo/GO_0051781 positive regulation of cell division Any process that activates or increases the frequency, rate or extent of somatic stem cell division. http://purl.obolibrary.org/obo/GO_1904745 Atg1/ULK1 kinase complex assembly http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly The aggregation, arrangement and bonding together of a set of components to form an Atg1/UKL1 kinase complex. http://purl.obolibrary.org/obo/GO_1905119 response to haloperidol http://purl.obolibrary.org/obo/GO_0097305 response to alcohol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus. http://purl.obolibrary.org/obo/GO_1905213 negative regulation of mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_1903379 regulation of mitotic chromosome condensation Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation. http://purl.obolibrary.org/obo/GO_1905419 sperm flagellum movement involved in flagellated sperm motility http://purl.obolibrary.org/obo/GO_0060294 cilium movement involved in cell motility The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm. http://purl.obolibrary.org/obo/GO_1905427 intracellular signal transduction involved in positive regulation of cell growth http://purl.obolibrary.org/obo/GO_0035556 intracellular signal transduction Any intracellular signal transduction that is involved in positive regulation of cell growth. http://purl.obolibrary.org/obo/GO_2000035 regulation of stem cell division http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division Any process that modulates the frequency, rate or extent of stem cell division. http://purl.obolibrary.org/obo/GO_2000252 negative regulation of feeding behavior http://purl.obolibrary.org/obo/GO_0060259 regulation of feeding behavior Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior. http://purl.obolibrary.org/obo/GO_2000253 positive regulation of feeding behavior http://purl.obolibrary.org/obo/GO_0060259 regulation of feeding behavior Any process that activates or increases the frequency, rate or extent of feeding behavior. http://purl.obolibrary.org/obo/UBERON_0000015 non-material anatomical boundary http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures. http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. http://purl.obolibrary.org/obo/UBERON_0000068 embryo stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A life cycle stage that starts with fertilization and ends with the fully formed embryo. http://purl.obolibrary.org/obo/UBERON_0000106 zygote stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A stage at which the organism is a single cell produced by means of sexual reproduction. http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity Anatomical entity that has mass. http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity Anatomical entity that has no mass. http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Anatomical structure which is a subdivision of a whole organism, consisting of components of multiple anatomical systems, largely surrounded by a contiguous region of integument. http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space Anatomical space which contains portions of one or more body substances and is bounded by the internal surface of one maximally connected anatomical structure. Examples: cranial cavity, pharyngeal recess space, nasal cavity, tooth socket, cavity of serous sac, lumen of stomach, lumen of artery, fornix of vagina. http://purl.obolibrary.org/obo/UBERON_0006983 anatomical point http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity Non-material anatomical entity of zero dimension, which forms a boundary of an anatomical line or surface. http://purl.obolibrary.org/obo/UBERON_0007567 regenerating anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that is undergoing regeneration. http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that connects two structures http://purl.obolibrary.org/obo/PLANA_0000001 Stage 1 http://purl.obolibrary.org/obo/UBERON_0000068 embryo stage A stage of Smed embryonic development, 0 - 2 days post-egg capsule deposition at 20˚C. Zygote and dispersed blastomere cleavage in a yolk syncytium. http://purl.obolibrary.org/obo/PLANA_0000002 Stage 2 http://purl.obolibrary.org/obo/UBERON_0000068 embryo stage A stage of Smed embryonic development defined by a unique gene expression signature and morphology, 2 - 3 days post-egg capsule deposition at 20˚C. Sphere formation. A fraction of the blastomeres differentiate into temporary embryonic tissues that provide form and function to the embryo. Undifferentiated blastomeres remain in the embryonic wall. http://purl.obolibrary.org/obo/PLANA_0000003 Stage 3 http://purl.obolibrary.org/obo/UBERON_0000068 embryo stage A stage of Smed embryonic development defined by a unique gene expression signature and morphology, 2 - 4 days post-egg capsule deposition at 20˚C. Dispersed blastomere cleavage in the embryonic wall of nascent spheres. Yolk ingestion into the gut cavity. http://purl.obolibrary.org/obo/PLANA_0000004 Stage 4 http://purl.obolibrary.org/obo/UBERON_0000068 embryo stage A stage of Smed embryonic development defined by a unique gene expression signature and morphology, 3 - 5 days post-egg capsule deposition at 20˚C. Dispersed blastomere cleavage in the embryonic wall. Yolk ingestion into the gut cavity. Early embryonic gut formation. http://purl.obolibrary.org/obo/PLANA_0000005 Stage 5 http://purl.obolibrary.org/obo/UBERON_0000068 embryo stage A stage of Smed embryonic development defined by a unique gene expression signature and morphology, 5-7 days post-egg capsule deposition at 20˚C. Organogenesis onset. Downregulation of early embryo enriched transcripts and birth of adult lineages within the blastomere population. Early embryonic gut formation continues. Yolk ingestion into the gut cavity. http://purl.obolibrary.org/obo/PLANA_0000006 Stage 6 http://purl.obolibrary.org/obo/UBERON_0000068 embryo stage A stage of Smed embryonic development defined by a unique gene expression signature and morphology, 7 - 9 days post-egg capsule deposition at 20˚C. Organogenesis and morphogenesis. Definitive organ formation. Temporary embryonic cell types degenerate. Embryo elongation. http://purl.obolibrary.org/obo/PLANA_0000007 Stage 7 http://purl.obolibrary.org/obo/UBERON_0000068 embryo stage A stage of Smed embryonic development defined by a unique gene expression signature and morphology, 9 - 11 days post-egg capsule deposition at 20˚C. Organogenesis and organ maturation continues. Embryos elongated. Eyes just visible. Onset of gliding motility. http://purl.obolibrary.org/obo/PLANA_0000008 Stage 8 http://purl.obolibrary.org/obo/UBERON_0000068 embryo stage A stage of Smed embryonic development defined by a unique gene expression signature and morphology, 13 - 15 days post-egg capsule deposition at 20˚C. Organogenesis and organ maturation continues. Hatching. http://purl.obolibrary.org/obo/PLANA_0000009 sigma neoblast http://purl.obolibrary.org/obo/PLANA_0000429 neoblast A heterogeneous subpopulation of neoblasts with enriched expression of SoxP-1 and SoxP-2 thought to contain both pluripotent stem cells and tissue-specific progenitors. http://purl.obolibrary.org/obo/PLANA_0000011 protonephridial progenitor cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity Neoblasts and post-mitotic, differentiating daughters coexpressing POU2-3, six1/2-2, Sal1, Eya and Osr,required for maintenance and regeneration of protonephridial cell types. http://purl.obolibrary.org/obo/PLANA_0000012 neural progenitor cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity Neoblasts and their differentiating daughters implicated in maintenance and regeneration of different tissues in the nervous system. http://purl.obolibrary.org/obo/PLANA_0000014 zeta neoblast http://purl.obolibrary.org/obo/PLANA_0000033 epidermal progenitor cell An abundant neoblast subclass consisting of p53+, zfp1+ progenitors required for maintenance and regeneration of epidermal cell type(s). http://purl.obolibrary.org/obo/PLANA_0000016 pharynx http://purl.obolibrary.org/obo/BFO_0000040 material entity A plicate and protrusible organ that is the sole point of entry and exit for the Triclad gut. It contains epithelial, muscular, secretory and neuronal cell types. http://purl.obolibrary.org/obo/PLANA_0000017 photoreceptor neuron http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity Bipolar photoreceptor neurons with dendritic projections into the optic cup and axons that innervate the underlying brain. http://purl.obolibrary.org/obo/PLANA_0000018 Category 4 cell http://purl.obolibrary.org/obo/PLANA_0000015 non ciliated epithelial cell Post-mitotic, mesenchymally and epidermally located progenitors downstream of the Category 3 cells. http://purl.obolibrary.org/obo/PLANA_0000019 muscle progenitor cell http://purl.obolibrary.org/obo/PLANA_0000120 progenitor cell Progenitor neoblasts implicated in the maintenance and regeneration of muscle fibers. http://purl.obolibrary.org/obo/PLANA_0000020 protonephridia http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity Excretory organs consisting of flame cells, proximal tubules, and distal tubules connected to a mesenchymal collecting duct. http://purl.obolibrary.org/obo/PLANA_0000022 Category 5 cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity Post-mitotic, ciliated epidermal cells. http://purl.obolibrary.org/obo/PLANA_0000023 embryonic pharynx http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity An innervated, muscular pump that ingests yolk cells into the gut cavity. The embryonic pharynx is an extraembryonic tissue that forms during Stage 2, functions during Stages 3-5, and degenerates during Stages 6-7. http://purl.obolibrary.org/obo/PLANA_0000025 nervous system http://purl.obolibrary.org/obo/PLANA_0000114 anatomical system The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organisms, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. http://purl.obolibrary.org/obo/PLANA_0000026 gut http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity The planarian triclad gut contains a central anterior gut branch connected to two posterior gut branches arranged around the pharynx. Secondary gut branches extend laterally from the primary gut branches, while tertiary gut branches extend from the secondary branches. Food and waste enter and exit the gut through the pharynx. http://purl.obolibrary.org/obo/PLANA_0000028 Category 2 cell http://purl.obolibrary.org/obo/PLANA_0002095 somatic cell Post-mitotic, mesenchymally located epidermal progenitors downstream of the zeta neoblasts. http://purl.obolibrary.org/obo/PLANA_0000029 primitive ectoderm http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A single cell layer of extraembryonic, post-mitotic ectodermal cells bounding the embryo. The primitive ectoderm forms during Stage 2 and is thought to degenerate as the definitive epidermis forms during Stages 5-7. http://purl.obolibrary.org/obo/PLANA_0000030 midline http://purl.obolibrary.org/obo/PLANA_0000102 anatomical region The median line/ plane of bilateral symmetry along the anteroposterior axis. http://purl.obolibrary.org/obo/PLANA_0000031 pigment cup cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity Non-neuronal, pigmented cells arrayed along the proximal side of the optic cup. http://purl.obolibrary.org/obo/PLANA_0000032 dorsal midline http://purl.obolibrary.org/obo/PLANA_0000038 ventral midline The median line/plane of bilateral symmetry along the anteroposterior axis on the dorsal surface of the animal. http://purl.obolibrary.org/obo/PLANA_0000033 epidermal progenitor cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity Mitotically active zeta neoblasts and their post-mitotic descendants which undergo progressive differentiation and outward directed movement through the mesenchyme prior to incorporation into the epidermis, where terminal differentiation occurs. http://purl.obolibrary.org/obo/PLANA_0000034 epidermis http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A single cell layer of post-mitotic epithelial cells containing ciliated and non-ciliated cell types forming the exterior surface of the animal. http://purl.obolibrary.org/obo/PLANA_0000035 Category 3 cell http://purl.obolibrary.org/obo/PLANA_0002095 somatic cell Post-mitotic, mesenchymally located epidermal progenitors downstream of the Category 2 cells. http://purl.obolibrary.org/obo/PLANA_0000036 eye http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity An organ that detects light. http://purl.obolibrary.org/obo/PLANA_0000038 ventral midline http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The median line/ plane of bilateral symmetry along the anteroposterior axis on the ventral surface of the animal. http://purl.obolibrary.org/obo/PLANA_0000039 gamma neoblast http://purl.obolibrary.org/obo/PLANA_0000429 neoblast An abundant neoblast subclass, exhibiting enriched expression of gata456a, hnf4, prox-1 and nkx2.2, implicated in maintenance and regeneration of the definitive gut. http://purl.obolibrary.org/obo/PLANA_0000041 aboral hemisphere http://purl.obolibrary.org/obo/PLANA_0000423 embryonic subdivision Stage 3-5 embryo hemisphere centered around the pole opposite the embryonic pharynx. http://purl.obolibrary.org/obo/PLANA_0000042 anterior primary gut branch http://purl.obolibrary.org/obo/PLANA_0002086 primary gut branch The single, central gut branch of the triclad gut anterior to the pharynx. http://purl.obolibrary.org/obo/PLANA_0000043 dorsal ventral margin of the whole animal http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Region along the edge of the animal where the dorsal and ventral surfaces meet. http://purl.obolibrary.org/obo/PLANA_0000044 cephalic ganglia http://purl.obolibrary.org/obo/BFO_0000040 material entity The planarian brain, consisting of two bilaterally symmetric lobes occupying a ventral position in the head. http://purl.obolibrary.org/obo/PLANA_0000045 circular muscle cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity Body wall muscle fibers arrayed around the dorsoventral axis. Upon regeneration, these are thought to be produced de novo in the blastema. http://purl.obolibrary.org/obo/PLANA_0000046 clonogenic neoblast http://purl.obolibrary.org/obo/PLANA_0002095 somatic cell Pluripotent piwi-1+ stem cells that self-renew, form expanding colonies and produce differentiating daughters that contribute to multiple organ systems. cNeoblasts are predicted to be broadly distributed across the anteroposterior axis of the adult worm. http://purl.obolibrary.org/obo/PLANA_0000047 collecting duct http://purl.obolibrary.org/obo/PLANA_0000113 tissue Non-ciliated tubules associated with the distal tubules, which cross the basement membrane and terminate in the dorsal epidermis. http://purl.obolibrary.org/obo/PLANA_0000048 diagonal muscle cell http://purl.obolibrary.org/obo/PLANA_0000101 muscle cell Body wall muscle fibers arrayed diagonally along the anteroposterior axis. http://purl.obolibrary.org/obo/PLANA_0000049 digestive system http://purl.obolibrary.org/obo/PLANA_0000114 anatomical system Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes. http://purl.obolibrary.org/obo/PLANA_0000053 distal tubule http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity Sinusoidal, non-ciliated tubules connected to proximal tubules within the parenchyma. Tubules are formed via intercellular junctions between two epithelial cells. http://purl.obolibrary.org/obo/PLANA_0000054 dorsal region of the epidermis http://purl.obolibrary.org/obo/PLANA_0000096 ventral epidermis Single cell layer of dorsal, post-mitotic, epithelial cells containing the dorsal stripe. http://purl.obolibrary.org/obo/PLANA_0000055 dorsal stripe http://purl.obolibrary.org/obo/PLANA_0002023 ciliated epithelium Ciliated epithelial cells along the dorsal midline. http://purl.obolibrary.org/obo/PLANA_0000056 ectolecithal embryo http://purl.obolibrary.org/obo/PLANA_0000116 embryo Turbellarian (freshwater flatworm) embryos that undergo a modified form of cleavage due to separation of oocyte and yolk. Yolk is not contained within oocytes, and is produced by somatic vitellogenic gland cells. http://purl.obolibrary.org/obo/PLANA_0000058 embryonic digestive system http://purl.obolibrary.org/obo/PLANA_0000063 extraembryonic structure A cryptic digestive system in Stage 3-6 embryos comprised of temporary embryonic cell types and organs, including the embryonic pharynx and primitive gut cells. Embryonic gut cells, likely produced from blastomeres, form a phagocytic tissue layer surrounding the inner gut cavity during Stages 4-6. It is not known whether the embryonic gut is temporary embryonic tissue or a definitive tissue. For convenience, the embryonic gut is currently designated as an extraembryonic structure because cell type specific markers for the embryonic gut do not stain the definitive gut in hatchlings or adult animals. http://purl.obolibrary.org/obo/PLANA_0000059 embryonic gut cell http://purl.obolibrary.org/obo/PLANA_0004518 extraembryonic cell Dispersed, phagocytic gut cells that appear during Stage 4 and ultimately generate a honeycomb-like lattice surrounding the central gut cavity in Stage 5 embryos. Early embryonic gut cell specific transcripts are expressed from Stage 4-6, and are downregulated during Stage 7. http://purl.obolibrary.org/obo/PLANA_0000060 embryonic wall http://purl.obolibrary.org/obo/PLANA_0000423 embryonic subdivision The parenchymal space between the gut cavity and the primitive ectoderm containing undifferentiated blastomeres in Stage 3-5 embryos. http://purl.obolibrary.org/obo/PLANA_0000061 enteric musculature http://purl.obolibrary.org/obo/PLANA_0000013 visceral musculature Visceral muscle surrounding the gut. http://purl.obolibrary.org/obo/PLANA_0000062 esophagus http://purl.obolibrary.org/obo/PLANA_0000113 tissue Attachment between the triclad gut and the proximal end of the pharynx. http://purl.obolibrary.org/obo/PLANA_0000063 extraembryonic structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure A multicellular anatomical structure that is associated with an embryo and derived from the zygote from which it develops, but which does not contribute to the embryo proper or to structures that are part of the same organism after embryogenesis. http://purl.obolibrary.org/obo/PLANA_0000064 flame bulb http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity Terminal structure of protonephridia unit; consists of flame cells. http://purl.obolibrary.org/obo/PLANA_0000065 flame cell http://purl.obolibrary.org/obo/PLANA_0000119 terminally differentiated cell Terminal structure of the protonephridia unit, capping the proximal tubules. Flame cells are defined by the filtration weir‚ or filtration diaphragm, which consists of closely apposed strands of cytoplasm surrounding a central cilia bundle, and by numerous microvilli between weir and cilia. Positive for acetyated tubulin. http://purl.obolibrary.org/obo/PLANA_0000066 gastrodermis http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity The single cell layer columnar epithelial lining of the intestine. The gastrodermis is surrounded by a basal lamina and enteric muscle. http://purl.obolibrary.org/obo/PLANA_0000067 goblet cell http://purl.obolibrary.org/obo/PLANA_0000105 secretory cell Secretory cells that release digestive enzymes into the lumen of the intestine. http://purl.obolibrary.org/obo/PLANA_0000068 embryonic gut cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity Cavity encompassed by the embryonic digestive tract, prior to formation of the branched defintive gut. http://purl.obolibrary.org/obo/PLANA_0000069 inner longitudinal muscle cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity Inner most body wall muscle fibers arrayed along the anteroposterior axis. These fibers are thicker than the outer longitudinal muscle fibers. The pattern of these muscles differs along the dorsoventral axis, with the dorsal arrangement converging at the central zone of the anterior pole. The ventral arrangement is more parallel or may diverge slightly as it approaches the ventral pole. http://purl.obolibrary.org/obo/PLANA_0000070 intestinal phagocyte http://purl.obolibrary.org/obo/PLANA_0000119 terminally differentiated cell Absorptive digestive cells that engulf food particles for intracellular digestion. http://purl.obolibrary.org/obo/PLANA_0000071 longitudinal muscle cell http://purl.obolibrary.org/obo/PLANA_0000101 muscle cell Body wall muscle fibers arrayed along the anteroposterior axis. Upon regeneration, these muscles are thought to be established from truncated pre-existing fibers.Inner most body wall muscle fibers arrayed along the anteroposterior axis. These fibers are thicker than the outer longitudinal muscle fibers. The pattern of these muscles differs along the dorsoventral axis, with the dorsal arrangement converging at the central zone of the anterior pole. The ventral arrangement is more parallel or may diverge slightly as it approaches the ventral pole. http://purl.obolibrary.org/obo/PLANA_0000072 mouth http://purl.obolibrary.org/obo/BFO_0000040 material entity The sole point of entry and exit for the Triclad planarian flatworm gut. The mouth is connected to the pharyngeal pouch to allow for exit and re-entry of the pharynx on the ventral side of the animal. The mouth contains several cell types, including epithelial cells, muscle, and secretory cells. http://purl.obolibrary.org/obo/PLANA_0000074 oocyte http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A female germ cell that has entered meiosis. http://purl.obolibrary.org/obo/PLANA_0000075 optic cup http://purl.obolibrary.org/obo/PLANA_0000113 tissue A portion of the eye containing pigment cells and dendritic projections from photoreceptor neurons. http://purl.obolibrary.org/obo/PLANA_0000076 oral hemisphere http://purl.obolibrary.org/obo/PLANA_0000423 embryonic subdivision Stage 3-5 embryo hemisphere centered around the embryonic pharynx. http://purl.obolibrary.org/obo/PLANA_0000078 outer longitudinal muscle cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity Body wall muscle fibers arrayed along the anteroposterior axis. Upon regeneration, these muscles are thought to be established from truncated pre-existing fibers. http://purl.obolibrary.org/obo/PLANA_0000079 parenchymal musculature http://purl.obolibrary.org/obo/BFO_0000040 material entity Muscles that are present through the mesenchyme, inclusing dorsal-ventral muscles, intestinal muscles and pharynx muscles. http://purl.obolibrary.org/obo/PLANA_0000080 peripheral nervous system http://purl.obolibrary.org/obo/PLANA_0000025 nervous system A major division of the nervous system that contains nerves which connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. http://purl.obolibrary.org/obo/PLANA_0000081 pharynx pouch http://purl.obolibrary.org/obo/PLANA_0000113 tissue An epithelial structure housing the pharynx, connected to the esophagus and mouth. http://purl.obolibrary.org/obo/PLANA_0000084 posterior primary gut branch http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity The primary gut branches of the triclad gut lateral and posterior to the pharynx and pharyngeal pouch. http://purl.obolibrary.org/obo/PLANA_0000085 primitive gut cell http://purl.obolibrary.org/obo/PLANA_0004518 extraembryonic cell A phagocytic cell closely associated with the embryonic pharynx. http://purl.obolibrary.org/obo/PLANA_0000087 proximal tubule http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity Ciliated epithelial cells form tubules, generating coiled, branching units terminating in flame bulbs. Tubules are formed via intercellular junctions between two epithelial cells. Proximal tubules are connected to non-ciliated distal tubules within the parenchyma. http://purl.obolibrary.org/obo/PLANA_0000088 renal system http://purl.obolibrary.org/obo/PLANA_0000114 anatomical system The renal system is an anatomical system that maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. http://purl.obolibrary.org/obo/PLANA_0000089 secondary gut branch http://purl.obolibrary.org/obo/PLANA_0002119 gut branch Gut branches, originating from and connected to the primary gut branches, that extend laterally towards the body edge. http://purl.obolibrary.org/obo/PLANA_0000090 sperm http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A mature male germ cell that develops from a spermatid. http://purl.obolibrary.org/obo/PLANA_0000092 yolk syncytium http://purl.obolibrary.org/obo/PLANA_0002136 syncytium Fused yolk cells surrounding blastomeres undergoing dispersed cleavage during Stages 1 and 2. http://purl.obolibrary.org/obo/PLANA_0000093 tertiary gut branch http://purl.obolibrary.org/obo/PLANA_0002119 gut branch Gut branches originating from and connected to the secondary gut branches. http://purl.obolibrary.org/obo/PLANA_0000095 trail cell http://purl.obolibrary.org/obo/PLANA_0000429 neoblast Ovo+ neoblasts and post-mitotic eye progenitors that simultaneously migrate and differentiate into photoreceptor neurons and non-neuronal pigment cup cells comprising the optic cup. http://purl.obolibrary.org/obo/PLANA_0000096 ventral epidermis http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Single cell layer of ventral, post-mitotic, heavily ciliated epithelial cells http://purl.obolibrary.org/obo/PLANA_0000097 ventral nerve cord http://purl.obolibrary.org/obo/BFO_0000040 material entity The pair of closely united ventral longitudinal nerves with their segmental ganglia that is characteristic of many elongate invertebrates (as earthworms)[BTO]. A large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring[WB]. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms[GO]. http://purl.obolibrary.org/obo/PLANA_0000098 zygote http://purl.obolibrary.org/obo/UBERON_0000068 embryo stage Diploid cell resulting from the fusion of male and female gametes at fertilization. [The_Dictionary_of_Cell_and_Molecular_Biology:Third_Edition ]. http://purl.obolibrary.org/obo/PLANA_0000099 neuron http://purl.obolibrary.org/obo/PLANA_0000540 electrically signaling cell The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. http://purl.obolibrary.org/obo/PLANA_0000100 epithelial cell http://purl.obolibrary.org/obo/PLANA_0000119 terminally differentiated cell A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where the apical part is directed towards the lumen and the basal part to the basal lamina. http://purl.obolibrary.org/obo/PLANA_0000101 muscle cell http://purl.obolibrary.org/obo/PLANA_0000539 electrically responsive cell A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. http://purl.obolibrary.org/obo/PLANA_0000102 anatomical region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A subdivision of an anatomical compartment. http://purl.obolibrary.org/obo/PLANA_0000103 central nervous system http://purl.obolibrary.org/obo/PLANA_0000025 nervous system The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. http://purl.obolibrary.org/obo/PLANA_0000104 rhabdite http://purl.obolibrary.org/obo/PLANA_0000430 epithelial cell component Straight or curved rod-like structures within the epidermal cells, oriented with long axis at right angles to the epidermal surface, that are discharged into mucous secretions. http://purl.obolibrary.org/obo/PLANA_0000105 secretory cell http://purl.obolibrary.org/obo/PLANA_0000119 terminally differentiated cell A cell that specializes in controlled release of one or more substances. http://purl.obolibrary.org/obo/PLANA_0000106 ciliated epithelial cell http://purl.obolibrary.org/obo/PLANA_0000100 epithelial cell An epithelial cell that has cilia. http://purl.obolibrary.org/obo/PLANA_0000107 yolk cell http://purl.obolibrary.org/obo/PLANA_0000119 terminally differentiated cell An extraembryonic cell, produced by somatic vitellogenic glands in adult hermaphrodites, that provides nutrition to the developing embryo. http://purl.obolibrary.org/obo/PLANA_0000110 pharynx progenitor cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity foxA1+ neoblasts and their post-mitotic, differentiating daughters required for maintenance and regeneration of the pharynx. http://purl.obolibrary.org/obo/PLANA_0000113 tissue http://purl.obolibrary.org/obo/PLANA_0000427 multicellular anatomical structure Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. http://purl.obolibrary.org/obo/PLANA_0000114 anatomical system http://purl.obolibrary.org/obo/PLANA_0000427 multicellular anatomical structure Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function. http://purl.obolibrary.org/obo/PLANA_0000116 embryo http://purl.obolibrary.org/obo/PLANA_0000215 reproductive system product Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. http://purl.obolibrary.org/obo/PLANA_0000117 embryonic structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Anatomical structure that is part of an embryo. http://purl.obolibrary.org/obo/PLANA_0000118 collecting duct epithelial cell http://purl.obolibrary.org/obo/PLANA_0000015 non ciliated epithelial cell Nonciliated epithelial cells that assemble into collecting ducts. http://purl.obolibrary.org/obo/PLANA_0000119 terminally differentiated cell http://purl.obolibrary.org/obo/PLANA_0002095 somatic cell A post-mitotic, terminally differentiated cell type found in planarian embryos, juveniles and/or adult animals. http://purl.obolibrary.org/obo/PLANA_0000120 progenitor cell http://purl.obolibrary.org/obo/PLANA_0000499 cell A cycling neoblast and/or post-mitotic cell that is primed or irreversibly committed to a tissue-specific differentation program http://purl.obolibrary.org/obo/PLANA_0000121 stem cell http://purl.obolibrary.org/obo/PLANA_0000499 cell A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/PLANA_0000122 gamete http://purl.obolibrary.org/obo/PLANA_0000227 germ cell A mature sexual reproductive cell having a single set of unpaired chromosomes. http://purl.obolibrary.org/obo/PLANA_0000123 embryonic cell http://purl.obolibrary.org/obo/PLANA_0000499 cell A cell of the embryo. http://purl.obolibrary.org/obo/PLANA_0000124 visual system http://purl.obolibrary.org/obo/PLANA_0000114 anatomical system The sensory system subserving the sense of vision. http://purl.obolibrary.org/obo/PLANA_0000125 sensory system http://purl.obolibrary.org/obo/PLANA_0000114 anatomical system Anatomical system that overlaps the nervous system and is responsible for receiving and processing sensory information. http://purl.obolibrary.org/obo/PLANA_0000126 reproductive system http://purl.obolibrary.org/obo/PLANA_0000114 anatomical system Anatomical system that has as its parts the organs concerned with reproduction. http://purl.obolibrary.org/obo/PLANA_0000127 oviduct epithelial cell http://purl.obolibrary.org/obo/PLANA_0000106 ciliated epithelial cell Ciliated epithelial cells that assemble into the oviduct. http://purl.obolibrary.org/obo/PLANA_0000128 sperm duct epithelial cell http://purl.obolibrary.org/obo/PLANA_0000106 ciliated epithelial cell Ciliated epithelial cells comprising the sperm ducts. http://purl.obolibrary.org/obo/BSPO_0000005 anatomical surface http://purl.obolibrary.org/obo/CARO_0000010 anatomical boundary A 2D surface of an anatomical continuant. http://purl.obolibrary.org/obo/BSPO_0000010 anatomical axis http://purl.obolibrary.org/obo/CARO_0000008 anatomical line A straight line through space, intersecting an anatomical entity. http://purl.obolibrary.org/obo/BSPO_0000013 anterior-posterior axis http://purl.obolibrary.org/obo/BSPO_0000010 anatomical axis An axis that extends through an organism from head end to opposite end of body or tail. http://purl.obolibrary.org/obo/BSPO_0000014 apical-basal axis relative to substrate http://purl.obolibrary.org/obo/BSPO_0000010 anatomical axis An axis that extends through an organism or organism part from the part of the organism or organism part attached to a substrate (basal) to the furthest from the attachment (apical). Note that the apical-basal axis is often used for organismal parts where there is attachment via a basal lamina or other structure. http://purl.obolibrary.org/obo/BSPO_0000015 proximal-distal axis http://purl.obolibrary.org/obo/BSPO_0000010 anatomical axis An axis that extends from the point of attachment of a structure (proximal) to the point furthest away from the plane of attachment (distal). http://purl.obolibrary.org/obo/BSPO_0000016 dorsal-ventral axis http://purl.obolibrary.org/obo/BSPO_0000010 anatomical axis An axis that is approximately perpendicular to the anterior-posterior axis and that extends through the horizontal plane of the body. http://purl.obolibrary.org/obo/BSPO_0000017 left-right axis http://purl.obolibrary.org/obo/BSPO_0000010 anatomical axis An axis that bisects an organism from left to right sides of body, through a sagittal plane. http://purl.obolibrary.org/obo/BSPO_0000018 transverse plane http://purl.obolibrary.org/obo/BSPO_0000400 anatomical plane Anatomical plane that divides body into anterior and posterior parts. http://purl.obolibrary.org/obo/BSPO_0000019 horizontal plane http://purl.obolibrary.org/obo/BSPO_0000400 anatomical plane Anatomical plane that divides bilateral body into dorsal and ventral parts. http://purl.obolibrary.org/obo/BSPO_0000026 antero-dorsal region http://purl.obolibrary.org/obo/BSPO_0000030 postero-dorsal region Anatomical region that overlaps the anterior and dorsal regions of a body or body part. http://purl.obolibrary.org/obo/BSPO_0000027 antero-ventral region http://purl.obolibrary.org/obo/BSPO_0000071 anterior region Anatomical region that overlaps the anterior and ventral regions of a body or body part. http://purl.obolibrary.org/obo/BSPO_0000028 postero-lateral region http://purl.obolibrary.org/obo/BSPO_0000082 lateral region Anatomical region that overlaps the posterior and lateral regions of the body or body part. http://purl.obolibrary.org/obo/BSPO_0000029 antero-lateral region http://purl.obolibrary.org/obo/BSPO_0000071 anterior region Anatomical region that overlaps the anterior and lateral regions of a body or body part. http://purl.obolibrary.org/obo/BSPO_0000030 postero-dorsal region http://purl.obolibrary.org/obo/BSPO_0000079 dorsal region Anatomical region that overlaps the posterior and dorsal regions of the body or body part. http://purl.obolibrary.org/obo/BSPO_0000035 postero-ventral region http://purl.obolibrary.org/obo/BSPO_0000084 ventral region Anatomical region that overlaps the posterior and ventral regions of a body or body part. http://purl.obolibrary.org/obo/BSPO_0000054 anatomical side http://purl.obolibrary.org/obo/BSPO_0000070 anatomical region An anatomical region bounded by a plane perpendicular to an axis through the middle. http://purl.obolibrary.org/obo/BSPO_0000055 anterior side http://purl.obolibrary.org/obo/BSPO_0000072 posterior region An anatomical region that is the entire part of an anatomical structure anterior to a transverse plane and bounded on one side by the same transverse plane. http://purl.obolibrary.org/obo/BSPO_0000056 posterior side http://purl.obolibrary.org/obo/BSPO_0000054 anatomical side An anatomical region that is the entire part of an anatomical structure posterior to a transverse plane and bounded on one side by the same transverse plane. http://purl.obolibrary.org/obo/BSPO_0000057 apical side http://purl.obolibrary.org/obo/BSPO_0000074 basal region Anatomical side that is located on the apical end of an organism or structure. http://purl.obolibrary.org/obo/BSPO_0000058 basal side http://purl.obolibrary.org/obo/BSPO_0000054 anatomical side Anatomical side that is located on the basal end of an organism or structure. http://purl.obolibrary.org/obo/BSPO_0000063 dorsal side http://purl.obolibrary.org/obo/BSPO_0000084 ventral region An anatomical region that is the entire part of an anatomical structure dorsal to a horizontal plane and bounded on one side by the same transverse plane. http://purl.obolibrary.org/obo/BSPO_0000068 ventral side http://purl.obolibrary.org/obo/BSPO_0000054 anatomical side An anatomical region that is the entire part of an anatomical structure ventral to a horizontal plane and bounded on one side by the same horizontal plane. http://purl.obolibrary.org/obo/BSPO_0000070 anatomical region http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure A 3D region in space without well-defined compartmental boundaries; for example, the dorsal region of an ectoderm. http://purl.obolibrary.org/obo/BSPO_0000071 anterior region http://purl.obolibrary.org/obo/BSPO_0000072 posterior region Anatomical region anteriorly located on the body or body part. http://purl.obolibrary.org/obo/BSPO_0000072 posterior region http://purl.obolibrary.org/obo/BSPO_0000070 anatomical region Anatomical region posteriorly located on the body or body part. http://purl.obolibrary.org/obo/BSPO_0000073 apical region http://purl.obolibrary.org/obo/BSPO_0000074 basal region Anatomical region located on the apical end on the body or body part. http://purl.obolibrary.org/obo/BSPO_0000074 basal region http://purl.obolibrary.org/obo/BSPO_0000070 anatomical region Anatomical region located basally on the body or body part. http://purl.obolibrary.org/obo/BSPO_0000079 dorsal region http://purl.obolibrary.org/obo/BSPO_0000084 ventral region Anatomical region dorsally located on the body or body part. http://purl.obolibrary.org/obo/BSPO_0000080 dorso-lateral region http://purl.obolibrary.org/obo/BSPO_0000085 ventro-lateral region Anatomical region that overlaps the dorsal and lateral regions of a body or body part. http://purl.obolibrary.org/obo/BSPO_0000082 lateral region http://purl.obolibrary.org/obo/BSPO_0000070 anatomical region Anatomical region laterally located on the body or body part. http://purl.obolibrary.org/obo/BSPO_0000084 ventral region http://purl.obolibrary.org/obo/BSPO_0000070 anatomical region Anatomical region ventrally located on the body or body part. http://purl.obolibrary.org/obo/BSPO_0000085 ventro-lateral region http://purl.obolibrary.org/obo/BSPO_0000084 ventral region Anatomical region that overlaps the ventral and lateral regions of a body or body part. http://purl.obolibrary.org/obo/BSPO_0000196 medial-external axis http://purl.obolibrary.org/obo/BSPO_0000010 anatomical axis An anatomical axis that extends from the center of the body outwards or externally. http://purl.obolibrary.org/obo/BSPO_0000198 oral-aboral axis http://purl.obolibrary.org/obo/BSPO_0000010 anatomical axis An axis that extends from the oral opening to the furthest point in an organism that is directly opposite. http://purl.obolibrary.org/obo/BSPO_0000371 anterior surface http://purl.obolibrary.org/obo/BSPO_0000005 anatomical surface Anatomical surface that is located on the anterior side of the body or body part. http://purl.obolibrary.org/obo/BSPO_0000372 posterior surface http://purl.obolibrary.org/obo/BSPO_0000005 anatomical surface Anatomical surface that is located on the posterior side of the body or body part. http://purl.obolibrary.org/obo/BSPO_0000373 apical surface http://purl.obolibrary.org/obo/BSPO_0000005 anatomical surface Anatomical surface that is located on the apical side of the body or body part. http://purl.obolibrary.org/obo/BSPO_0000374 basal surface http://purl.obolibrary.org/obo/BSPO_0000005 anatomical surface Anatomical surface that is located on the basal side of the body or body part. http://purl.obolibrary.org/obo/BSPO_0000379 dorsal surface http://purl.obolibrary.org/obo/BSPO_0000005 anatomical surface Anatomical surface that located on the dorsal side of the body or body part. http://purl.obolibrary.org/obo/BSPO_0000382 lateral surface http://purl.obolibrary.org/obo/BSPO_0000005 anatomical surface Anatomical surface that located on the lateral side of the body or body part. http://purl.obolibrary.org/obo/BSPO_0000384 ventral surface http://purl.obolibrary.org/obo/BSPO_0000005 anatomical surface Anatomical surface that is located on the ventral side of the body or body part. http://purl.obolibrary.org/obo/BSPO_0000400 anatomical plane http://purl.obolibrary.org/obo/CARO_0000010 anatomical boundary A flat 2D plane intersecting an anatomical continuant, dividing it into two adjacent portions. http://purl.obolibrary.org/obo/BSPO_0000417 sagittal plane http://purl.obolibrary.org/obo/BSPO_0000400 anatomical plane Anatomical plane that divides a bilateral body into left and right parts, not necessarily of even size. http://purl.obolibrary.org/obo/BSPO_0001001 medial-lateral axis http://purl.obolibrary.org/obo/BSPO_0000196 medial-external axis An axis that extends from the center of organism to one or other side. http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection http://purl.obolibrary.org/obo/GO_0042995 cell projection A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. http://purl.obolibrary.org/obo/GO_0062012 regulation of small molecule metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the rate, frequency or extent of a small molecule metabolic process. http://purl.obolibrary.org/obo/PLANA_0002000 adenal rhabdite http://purl.obolibrary.org/obo/PLANA_0000104 rhabdite Rhabdites that are located basally to the epidermis, in the mesenchyme. In Smed these are present in cells likely on their way to becoming part of the mature epidermis. http://purl.obolibrary.org/obo/PLANA_0002001 adherens junction http://purl.obolibrary.org/obo/PLANA_0000506 cell junction A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments. http://purl.obolibrary.org/obo/PLANA_0002002 adhesive papilla http://purl.obolibrary.org/obo/BFO_0000040 material entity Finger-like processes at the terminal pore of adhesive gland cells around the marginal adhesive zone. They protrude past the epidermis and are longer microvilli, and shorter than cilia. http://purl.obolibrary.org/obo/PLANA_0002003 amputation http://purl.obolibrary.org/obo/PLANA_0002026 cut A wound resulting in two or more separate tissue fragments. http://purl.obolibrary.org/obo/PLANA_0002004 anterior gut branch http://purl.obolibrary.org/obo/PLANA_0002119 gut branch A branch of the triclad gut located anterior to the pharynx. http://purl.obolibrary.org/obo/PLANA_0002005 anterior tip http://purl.obolibrary.org/obo/PLANA_0000102 anatomical region The anterior-medial region of the head margin. http://purl.obolibrary.org/obo/PLANA_0002006 antrum http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity A chamber formation in an organ. http://purl.obolibrary.org/obo/PLANA_0002007 auricle http://purl.obolibrary.org/obo/BFO_0000040 material entity A sense organ located along the dorsolateral head margin. The auricular groove is highly innervtated by ciliated sensory neurons, and has an altered epidermis devoid of rhabdites and gland cells. http://purl.obolibrary.org/obo/PLANA_0002008 axon http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. http://purl.obolibrary.org/obo/PLANA_0002009 axoneme http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. http://purl.obolibrary.org/obo/PLANA_0002010 basal body http://purl.obolibrary.org/obo/BFO_0000004 independent continuant A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport. http://purl.obolibrary.org/obo/PLANA_0002011 brain visual center http://purl.obolibrary.org/obo/PLANA_0000113 tissue Region of the cephalic ganglia innervated by the optic nerve (posterior-projecting photoreceptor neuron fasiculated axons). http://purl.obolibrary.org/obo/PLANA_0002012 bulbar cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity An enlarged portion of the seminal vesicle, comprised of secretory epithelial cells, that connects to the ejaculatory duct within the penis papilla. http://purl.obolibrary.org/obo/PLANA_0002013 Category 1 cell http://purl.obolibrary.org/obo/PLANA_0003116 parenchymal cell Irradiation-sensitive, mesenchymal cells that are absent from the head region anterior to the eyes and the pharynx. The Category 1 designation encompasses the neoblast population. http://purl.obolibrary.org/obo/PLANA_0002014 cell body http://purl.obolibrary.org/obo/GO_0005575 cellular_component The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections. http://purl.obolibrary.org/obo/PLANA_0002015 cephalic ganglia lobe http://purl.obolibrary.org/obo/PLANA_0000113 tissue One of two bilaterally symmetric structures comprising the planarian brain. http://purl.obolibrary.org/obo/PLANA_0002016 cephalic ganglia neuron http://purl.obolibrary.org/obo/BFO_0000040 material entity A central nervous system neuron located within the planarian brain. http://purl.obolibrary.org/obo/PLANA_0002017 chemical amputation http://purl.obolibrary.org/obo/PLANA_0002108 wound Amputation carried out by application of chemicals. http://purl.obolibrary.org/obo/PLANA_0002018 chemical pharynx amputation http://purl.obolibrary.org/obo/PLANA_0002017 chemical amputation Amputation of the phaynx, including the esophagus, by treatment with Sodium Azide. http://purl.obolibrary.org/obo/PLANA_0002019 chemosensory neuron http://purl.obolibrary.org/obo/PLANA_0000552 sensory neuron Any neuron that capable of some detection of chemical stimulus involved in sensory perception. http://purl.obolibrary.org/obo/PLANA_0002020 chromatoid body http://purl.obolibrary.org/obo/PLANA_0000531 non-membrane-bounded organelle A membrane-less, cytoplasmic ribonucleoprotein granule present in neoblasts and germ cells implicated in post-transcriptional regulation. The RNA helicase DHH1/RCK, Tudor, SmB, methylated substrates of PRMT5, PIWI-3 and Germinal Histone H4 localize to chromatoid bodies in neoblasts. http://purl.obolibrary.org/obo/PLANA_0002021 chromosome http://purl.obolibrary.org/obo/PLANA_0000532 nuclear part A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. http://purl.obolibrary.org/obo/PLANA_0002022 chromosome arm http://purl.obolibrary.org/obo/PLANA_0000532 nuclear part Under the microscope chromosomes appear as thin, thread-like structures. They all have a short arm and long arm separated by a primary constriction called the centromere. The short arm is designated as p and the long arm as q. http://purl.obolibrary.org/obo/PLANA_0002023 ciliated epithelium http://purl.obolibrary.org/obo/PLANA_0002118 epithelium Epithelium bearing vibratile cilia on the free surface. http://purl.obolibrary.org/obo/PLANA_0002024 cilium http://purl.obolibrary.org/obo/BFO_0000004 independent continuant A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body. The longitudinal array of microtubules are almost always in a 9+2 array with 2 microtubles in the central cilia bundle and 9 sets of doublet microtubules around the perimeter. The exception to this arrangement is spermatazoa flagella, which have a 9+1 array in planarians. http://purl.obolibrary.org/obo/PLANA_0002025 commissure http://purl.obolibrary.org/obo/PLANA_0000113 tissue A bundle of nerve fibers crossing from one side to the other side of the brain or spinal cord. http://purl.obolibrary.org/obo/PLANA_0002026 cut http://purl.obolibrary.org/obo/PLANA_0002099 surgical wound A wound or cleft resulted from tissue separation into parts or laid open or penetrated with a sharp edge or instrument. http://purl.obolibrary.org/obo/PLANA_0002027 dendrite http://purl.obolibrary.org/obo/BFO_0000004 independent continuant A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body. http://purl.obolibrary.org/obo/PLANA_0002028 dorsal-ventral muscle cell http://purl.obolibrary.org/obo/PLANA_0000101 muscle cell A muscle cell that runs in the transverse plane that connects the dorsal and ventral sides of the animal. http://purl.obolibrary.org/obo/PLANA_0002029 early female germ cell http://purl.obolibrary.org/obo/BFO_0000040 material entity A premeiotic female germ cell (i.e., a diploid female germline stem cell or transit amplifying oogonial cell). http://purl.obolibrary.org/obo/PLANA_0002030 early male germ cell http://purl.obolibrary.org/obo/BFO_0000040 material entity A premeiotic male germ cell (i.e., a spermatogonial stem cell or transit amplifying spermatogonial cell). http://purl.obolibrary.org/obo/PLANA_0002031 embryonic gut http://purl.obolibrary.org/obo/PLANA_0002120 extraembryonic organ A cryptic digestive cavity comprised of phagocytic embryonic gut cells. http://purl.obolibrary.org/obo/PLANA_0002032 epidermal cell http://purl.obolibrary.org/obo/PLANA_0000100 epithelial cell An epithelial cell of the integument (the outer layer of an organism). http://purl.obolibrary.org/obo/PLANA_0002033 epidermal rhabdite http://purl.obolibrary.org/obo/PLANA_0000104 rhabdite Rhabdites located within epidermal cells. http://purl.obolibrary.org/obo/PLANA_0002034 ER membrane http://purl.obolibrary.org/obo/PLANA_0000521 bounding membrane of organelle The lipid bilayer surrounding the endoplasmic reticulum. http://purl.obolibrary.org/obo/PLANA_0002035 eumelanin http://purl.obolibrary.org/obo/GO_0005575 cellular_component The black pigment that gives non-neuronal pigment cells of the optic cup their characteristic color. http://purl.obolibrary.org/obo/PLANA_0002036 excretory cell http://purl.obolibrary.org/obo/PLANA_0000119 terminally differentiated cell A cell involved in the elimination of metabolic and foreign toxins, and in maintaining the ionic, acid-base and water balance of biological fluids. http://purl.obolibrary.org/obo/PLANA_0002037 extracellular matrix http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues. http://purl.obolibrary.org/obo/PLANA_0002038 extracellular space http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. http://purl.obolibrary.org/obo/PLANA_0002039 fission http://purl.obolibrary.org/obo/PLANA_0002108 wound A form of asexual reproduction resulting in self-amputation of posterior tissue, generating an anterior fragment and a fission fragment. http://purl.obolibrary.org/obo/PLANA_0002040 flagellum http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Planarian undulipodia consisting of spermatazoa cell posterior protrusions. Planarian spermatozoa contain two flagella and are composed of 9 + 1 axonemal microtubule arrangements in their flagella (markedly different from the 9 + 2 structures generally observed in sperm of other animals). http://purl.obolibrary.org/obo/PLANA_0002041 gap junction http://purl.obolibrary.org/obo/PLANA_0000507 cell-cell junction A cell-cell junction composed of pannexins or innexins and connexins, two different families of channel-forming proteins. http://purl.obolibrary.org/obo/PLANA_0002042 genital atrium http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity A chamber where egg capsules are formed. One or more zygotes and yolk cells produced by the vitelline glands collect in the genital atrium; glands surrounding the genital atrium produce the egg capsule shell. http://purl.obolibrary.org/obo/PLANA_0002043 germ cell cyst http://purl.obolibrary.org/obo/PLANA_0002136 syncytium A clonally-related group of interconnected spermatogonial or oogonial cells, enveloped by somatic gonadal cells. http://purl.obolibrary.org/obo/PLANA_0002044 germline stem cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity Stem cell that is the precursor of gametes. http://purl.obolibrary.org/obo/PLANA_0002045 glycogen granule http://purl.obolibrary.org/obo/PLANA_0002137 intracellular granule Cytoplasmic bead-like structures of animal cells, visible by electron microscope. Each granule is a functional unit with the biosynthesis and catabolism of glycogen being catalyzed by enzymes bound to the granule surface. http://purl.obolibrary.org/obo/PLANA_0002046 incision http://purl.obolibrary.org/obo/PLANA_0002026 cut A breach of the epidermis made with a defined edge or point. http://purl.obolibrary.org/obo/PLANA_0002047 pharynx inner epidermal cell http://purl.obolibrary.org/obo/PLANA_0002032 epidermal cell Epithelial cells lining the inside of the pharynx. In Smed, distally located cells are heavily ciliated. http://purl.obolibrary.org/obo/PLANA_0002048 inner zone of gland cells http://purl.obolibrary.org/obo/PLANA_0000113 tissue Gland or secretory cells sandwiched between muscle and epidermal layers in the pharynx. http://purl.obolibrary.org/obo/PLANA_0002049 intercellular junction http://purl.obolibrary.org/obo/PLANA_0000507 cell-cell junction A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals. http://purl.obolibrary.org/obo/PLANA_0002050 linear amputation http://purl.obolibrary.org/obo/PLANA_0002003 amputation An amputation performed with a transverse, oblique or longitudinal cut. http://purl.obolibrary.org/obo/PLANA_0002051 linear incision http://purl.obolibrary.org/obo/PLANA_0002046 incision A breach of the epidermis and optionally down into other structures though an insult with a knife or other instrument, such that the movement includes the z direction and one or more of the x y direction. http://purl.obolibrary.org/obo/PLANA_0002052 lipid droplet http://purl.obolibrary.org/obo/PLANA_0000519 intracellular non-membrane-bounded organelle An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins. http://purl.obolibrary.org/obo/PLANA_0002053 lumen http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity The cavity or channel within a tube or tubular organ such as a blood vessel or the intestine. http://purl.obolibrary.org/obo/PLANA_0002054 marginal adhesive zone http://purl.obolibrary.org/obo/BSPO_0000086 anatomical compartment Zone present along the lateral dorsoventral boundary that sits just underneath the animal, in contact with substrates. It is comprised of bunches of adhesion gland cells whose terminal pores form pore rosettes through the dorsal ventral boundary epidermis.This region of is devoid of rhabdites. http://purl.obolibrary.org/obo/PLANA_0002055 mechanosensory neuron http://purl.obolibrary.org/obo/PLANA_0000552 sensory neuron Any neuron that is capable of some detection of mechanical stimulus involved in sensory perception. http://purl.obolibrary.org/obo/PLANA_0002056 medial muscle cell http://purl.obolibrary.org/obo/PLANA_0000101 muscle cell Subset of dorsal-ventral muscle cells located in the medial body region. http://purl.obolibrary.org/obo/PLANA_0002057 meiotic germ cell http://purl.obolibrary.org/obo/PLANA_0000227 germ cell A germ cell undergoing meiosis. http://purl.obolibrary.org/obo/PLANA_0002058 melanosome http://purl.obolibrary.org/obo/BFO_0000040 material entity A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells. http://purl.obolibrary.org/obo/PLANA_0002059 mucus http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure A secreted, mucin-rich extracellular substance coating the epidermal surface of the animal implicated in gliding locomotion, substrate adhesion, innate immunity and predator avoidance. http://purl.obolibrary.org/obo/PLANA_0002060 nephridiopore http://purl.obolibrary.org/obo/PLANA_0002079 pore The external opening and terminus of a protonephridium made by a terminal cell. http://purl.obolibrary.org/obo/PLANA_0002061 neurite http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Cell appendage of the neuron which includes the axon and the dendrite. http://purl.obolibrary.org/obo/PLANA_0002062 neuropeptidergic neuron http://purl.obolibrary.org/obo/PLANA_0000099 neuron A neuron that produces and releases neuropeptides at chemical synapses. http://purl.obolibrary.org/obo/PLANA_0002063 non-ciliated epidermis http://purl.obolibrary.org/obo/PLANA_0000034 epidermis Differentiating, immature epidermal cells lacking cilia. http://purl.obolibrary.org/obo/PLANA_0002064 nuclear envelope http://purl.obolibrary.org/obo/PLANA_0000520 membrane The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space). http://purl.obolibrary.org/obo/PLANA_0002065 nuclear inner membrane http://purl.obolibrary.org/obo/PLANA_0000522 membrane part The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope. http://purl.obolibrary.org/obo/PLANA_0002066 nuclear lumen http://purl.obolibrary.org/obo/PLANA_0000532 nuclear part The volume enclosed by the nuclear inner membrane. http://purl.obolibrary.org/obo/PLANA_0002067 nuclear outer membrane http://purl.obolibrary.org/obo/PLANA_0000522 membrane part The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes. http://purl.obolibrary.org/obo/PLANA_0002068 nuclear periphery http://purl.obolibrary.org/obo/PLANA_0000532 nuclear part The portion of the nuclear lumen proximal to the inner nuclear membrane. http://purl.obolibrary.org/obo/PLANA_0002069 ommochrome pigment cell http://purl.obolibrary.org/obo/PLANA_0002075 pigment cell Parenchymal cells that synthesize and contain brown ommonchrome pigment. http://purl.obolibrary.org/obo/PLANA_0002070 optic nerve http://purl.obolibrary.org/obo/BFO_0000040 material entity A neuron projection bundle that connects the retina or its analog in the eye with the brain. This includes the vertebrate optic nerve (not truly a nerve) as well as analogous structures such as the Bolwig nerve in Drosophila. http://purl.obolibrary.org/obo/PLANA_0002071 pharynx outer epidermal cell http://purl.obolibrary.org/obo/PLANA_0002032 epidermal cell Heavily ciliated, insunk epithelial cells bounding the outside of the pharynx. Outer pharynx epithelial cell nuclei are positioned beneath the pharynx musculature. http://purl.obolibrary.org/obo/PLANA_0002073 phagocytic cell http://purl.obolibrary.org/obo/PLANA_0000119 terminally differentiated cell A cell that engulfs large particles or cells via invagination of the plasma membrane and creation of a phagosome. http://purl.obolibrary.org/obo/PLANA_0002074 pharynx tip http://purl.obolibrary.org/obo/PLANA_0000113 tissue The distal-most end of the pharnyx containing an opening to the pharynx lumen. http://purl.obolibrary.org/obo/PLANA_0002075 pigment cell http://purl.obolibrary.org/obo/PLANA_0000119 terminally differentiated cell A pigment cell is a cell that contains pigment granules. http://purl.obolibrary.org/obo/PLANA_0002076 pigment granule http://purl.obolibrary.org/obo/BFO_0000004 independent continuant A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes. http://purl.obolibrary.org/obo/PLANA_0002077 plug amputation http://purl.obolibrary.org/obo/PLANA_0002003 amputation An amputation of tissue, usually though the whole depth of the animal encompassing both dorsal and ventral sides, often made with a biopsy punch. http://purl.obolibrary.org/obo/PLANA_0002078 point incision http://purl.obolibrary.org/obo/PLANA_0002046 incision A breach of the epidermis made with a defined edge or point. http://purl.obolibrary.org/obo/PLANA_0002079 pore http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity An anatomical space that is an opening, usually at the end of a canal or duct, on the surface of the integument or the lining of an internal anatomical space. http://purl.obolibrary.org/obo/PLANA_0002080 post-meiotic germ cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A haploid gamete undergoing terminal differentiation. http://purl.obolibrary.org/obo/PLANA_0002081 postsynaptic cell http://purl.obolibrary.org/obo/PLANA_0000499 cell A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane. http://purl.obolibrary.org/obo/PLANA_0002082 premeiotic germ cell http://purl.obolibrary.org/obo/PLANA_0000227 germ cell A diploid germline stem cell or transit amplifying germ cell that has not committed to undergoing meiotic DNA replication, reductive divisions or terminal differentiation. http://purl.obolibrary.org/obo/PLANA_0002083 presynaptic cell http://purl.obolibrary.org/obo/PLANA_0000099 neuron The part of a synapse that is part of the presynaptic cell. http://purl.obolibrary.org/obo/PLANA_0002084 presynaptic terminal http://purl.obolibrary.org/obo/GO_0005575 cellular_component Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. http://purl.obolibrary.org/obo/PLANA_0002085 presynaptic vesicle http://purl.obolibrary.org/obo/BFO_0000004 independent continuant A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane. http://purl.obolibrary.org/obo/PLANA_0002086 primary gut branch http://purl.obolibrary.org/obo/PLANA_0002119 gut branch The largest branch of the triclad intestine. It is comprised of the gastrodermis, a columnar epithelium, surrounded by basal lamina and visceral musculature. http://purl.obolibrary.org/obo/PLANA_0002087 primitive gut http://purl.obolibrary.org/obo/PLANA_0002120 extraembryonic organ Four large phagocytic cells associated with the embryonic pharynx. http://purl.obolibrary.org/obo/PLANA_0002088 quarternary gut branch http://purl.obolibrary.org/obo/PLANA_0002119 gut branch Gut branches originating from and connected to the tertiary gut branches. http://purl.obolibrary.org/obo/PLANA_0002089 reproductive organ http://purl.obolibrary.org/obo/PLANA_0000431 organ An organ involved in reproduction http://purl.obolibrary.org/obo/PLANA_0002090 reproductive structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Any anatomical structure that is part of the reproductive system. http://purl.obolibrary.org/obo/PLANA_0002091 rhabdome http://purl.obolibrary.org/obo/PLANA_0000113 tissue The light sensing structure consisting of photoreceptor neuron dendrites that project into the optic lumen and show close associations with eumelanin-containing pigment cup cells. http://purl.obolibrary.org/obo/PLANA_0002092 rhabdomere http://purl.obolibrary.org/obo/BFO_0000040 material entity The dendritic process of a bipolar photoreceptor neuron that projects into the optic cup lumen and senses light. http://purl.obolibrary.org/obo/PLANA_0002093 secretory duct http://purl.obolibrary.org/obo/PLANA_0000113 tissue A tubular structure that transports secreted or excreted substances. http://purl.obolibrary.org/obo/PLANA_0002094 secretory granule http://purl.obolibrary.org/obo/BFO_0000004 independent continuant A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules. http://purl.obolibrary.org/obo/PLANA_0002095 somatic cell http://purl.obolibrary.org/obo/PLANA_0000499 cell One of the cells of the body that compose the tissues, organs, and parts of that individual other than the germ cells. http://purl.obolibrary.org/obo/PLANA_0002096 somatic gonadal cell http://purl.obolibrary.org/obo/PLANA_0000119 terminally differentiated cell A non-germline cell within the ovary or testis. http://purl.obolibrary.org/obo/PLANA_0002097 specialized neoblast http://purl.obolibrary.org/obo/PLANA_0000429 neoblast A presumptive progenitor cell that expresses both pan-neoblast markers and pro-differentiation gene(s), frequently developmental transcription factors, implicated in lineage commitment and tissue-specific differentiation programs. http://purl.obolibrary.org/obo/PLANA_0002098 stalk http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure A thin, flexible rod that anchors an egg capsule to a solid substrate. http://purl.obolibrary.org/obo/PLANA_0002099 surgical wound http://purl.obolibrary.org/obo/PLANA_0002108 wound A wound produced by non-autonomous physical means. http://purl.obolibrary.org/obo/PLANA_0002100 synapse http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. http://purl.obolibrary.org/obo/PLANA_0002101 synaptic cleft http://purl.obolibrary.org/obo/PLANA_0002038 extracellular space The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released. http://purl.obolibrary.org/obo/PLANA_0002102 synaptic vesicle http://purl.obolibrary.org/obo/BFO_0000004 independent continuant A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane. http://purl.obolibrary.org/obo/PLANA_0002103 synaptonemal complex http://purl.obolibrary.org/obo/PLANA_0002123 chromosomal_structural_element A proteinaceous scaffold found between homologous chromosomes during meiosis. It consists of 2 lateral elements and a central element, all running parallel to each other. Transverse filaments connect the lateral elements to the central element. http://purl.obolibrary.org/obo/PLANA_0002104 tail tip http://purl.obolibrary.org/obo/PLANA_0000102 anatomical region The posterior-medial region of the tail margin. http://purl.obolibrary.org/obo/PLANA_0002105 telomere http://purl.obolibrary.org/obo/PLANA_0002121 chromosome_part The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated proteins. http://purl.obolibrary.org/obo/PLANA_0002106 septate junction http://purl.obolibrary.org/obo/BFO_0000004 independent continuant A cell-cell junction in invertebrates that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. http://purl.obolibrary.org/obo/PLANA_0002107 wedge amputation http://purl.obolibrary.org/obo/PLANA_0002003 amputation A piece of tissue removed from the lateral margin at any given point that extendes interiorly to more medial structures. http://purl.obolibrary.org/obo/PLANA_0002108 wound http://purl.obolibrary.org/obo/PLANA_0002122 perturbation An injury that breaches the epidermis. http://purl.obolibrary.org/obo/PLANA_0002109 X1 cell http://purl.obolibrary.org/obo/PLANA_0002138 FACS sorted cell population A sorted cell population enriched for irradiation-sensitive, cycling cells (4n cells, with high levels of Hoescht 33342 staining) with scant cytoplasm (low levels of calcein-AM staining). X1 cells are enriched for cycling neoblasts. http://purl.obolibrary.org/obo/PLANA_0002110 X1(FS) cell http://purl.obolibrary.org/obo/PLANA_0002138 FACS sorted cell population A heterogeneous sorted cell population of unstained planarian cells with similar size and complexity to irradiation-sensitive, cycling cells contained in the X1 gate. Unlike X1 cells, X1(FS) cells are amenable to cell transplantation. http://purl.obolibrary.org/obo/PLANA_0002111 X2 cell http://purl.obolibrary.org/obo/PLANA_0002138 FACS sorted cell population A sorted cell population containing irradiation-sensitive and irradiation-insensitive cells, characterized by weak Hoescht 33342 and calcein-AM staining. X2 cell populations contain neoblasts as well as a variety of lineage-dedicated post-mitotic progenitor cells. http://purl.obolibrary.org/obo/PLANA_0002112 Xins cell http://purl.obolibrary.org/obo/PLANA_0002138 FACS sorted cell population A sorted cell population of irradiation-insensitive cells that contains a variety of post-mitotic, differentiated cell types. http://purl.obolibrary.org/obo/PLANA_0002113 post-pharyngeal region http://purl.obolibrary.org/obo/PLANA_0000102 anatomical region Posterior to the pharynx. http://purl.obolibrary.org/obo/PLANA_0002114 post-blastema region http://purl.obolibrary.org/obo/BSPO_0000070 anatomical region Adjacent to blastema, or proximal to blastema. http://purl.obolibrary.org/obo/PLANA_0002116 fission fragment http://purl.obolibrary.org/obo/PLANA_0002128 fragment A fragment derived from a spontaneous or induced fission event. http://purl.obolibrary.org/obo/PLANA_0002118 epithelium http://purl.obolibrary.org/obo/PLANA_0000113 tissue The avascular cellular layers that cover body surfaces and cavities and may form glands. http://purl.obolibrary.org/obo/PLANA_0002119 gut branch http://purl.obolibrary.org/obo/PLANA_0000113 tissue The triclad planarian gut is serially bifrucated into connected lumens where each bifrucation is a branch. http://purl.obolibrary.org/obo/PLANA_0002120 extraembryonic organ http://purl.obolibrary.org/obo/PLANA_0000431 organ Organ that is associated with an embryo and derived from the zygote from which it develops, but which does not contribute to the embryo proper or to structures that are part of the same organism after embryogenesis. http://purl.obolibrary.org/obo/PLANA_0002121 chromosome_part http://purl.obolibrary.org/obo/PLANA_0000532 nuclear part This is a manufactured term, that serves the purpose of allow the parts of a chromosome to have an is_a path to the root. http://purl.obolibrary.org/obo/PLANA_0002123 chromosomal_structural_element http://purl.obolibrary.org/obo/PLANA_0002121 chromosome_part structural element of a chromosome, for example, a telomere and a centromere http://purl.obolibrary.org/obo/PLANA_0002125 thick fragment http://purl.obolibrary.org/obo/PLANA_0003608 longitudinal fragment A longitudinal fragment containing the preexisting midline and medial structures. http://purl.obolibrary.org/obo/PLANA_0002126 thin fragment http://purl.obolibrary.org/obo/PLANA_0003608 longitudinal fragment A longitudinal fragment lacking a midline and medial structures. http://purl.obolibrary.org/obo/PLANA_0002128 fragment http://purl.obolibrary.org/obo/UBERON_0007567 regenerating anatomical structure A piece of tissue isolated from the body. http://purl.obolibrary.org/obo/PLANA_0002129 longitudinal region http://purl.obolibrary.org/obo/BSPO_0000070 anatomical region A region bounded by any sagittal plane though the animal and the left or right side of the animal. NOTE: sagittal plane is an anatomical plane that divides a bilateral body into left and right parts, not necessarily of even size http://purl.obolibrary.org/obo/PLANA_0002130 chemical wound http://purl.obolibrary.org/obo/PLANA_0002108 wound An intentional wound produced by non-autonomous chemical means. http://purl.obolibrary.org/obo/PLANA_0002131 plug wound http://purl.obolibrary.org/obo/PLANA_0002108 wound A wound resulting from the removal of tissue, usually though the whole depth of the animal encompassing both dorsal and ventral sides, often made with a biopsy punch. http://purl.obolibrary.org/obo/PLANA_0002132 wedge wound http://purl.obolibrary.org/obo/PLANA_0002108 wound A wound resulting from the removal of a piece of tissue from the lateral margin at any given point that extends interiorly to more medial structures. http://purl.obolibrary.org/obo/PLANA_0002133 regenerating fragment http://purl.obolibrary.org/obo/PLANA_0002128 fragment A fragment that has undergone wound healing and is undergoing tissue replacement and morphallaxis. http://purl.obolibrary.org/obo/PLANA_0002134 sagittal orientation http://purl.obolibrary.org/obo/PATO_0005024 longitudinal orientation An orientation quality inhering in a bearer by virtue of the bearer having a position that is in the sagittal plane. This plane runs longitudinally and is not necessarily medial. http://purl.obolibrary.org/obo/PLANA_0002135 parasagittal orientation http://purl.obolibrary.org/obo/PLANA_0002134 sagittal orientation An orientation quality inhering in a bearer by virtue of the bearer having a position that is in the parasagittal plane, which runs longitudinally, and is never medial. http://purl.obolibrary.org/obo/PLANA_0002136 syncytium http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical entity consisting of a single or a few multinucleated structures http://purl.obolibrary.org/obo/PLANA_0002137 intracellular granule http://purl.obolibrary.org/obo/PLANA_0000519 intracellular non-membrane-bounded organelle Cytoplasmic part which forms a distinctive granular particle, which may or may not be visible using light microscopy. http://purl.obolibrary.org/obo/PLANA_0002138 FACS sorted cell population http://purl.obolibrary.org/obo/PLANA_0002139 derived cell population Any number of cells from dissociated planarian tissue sorted via a FACS sorter for any parameter. http://purl.obolibrary.org/obo/PLANA_0002139 derived cell population http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity Cells isolated from dissociated planarian tissue. http://purl.obolibrary.org/obo/PLANA_0002140 pharynx pouch epithelium http://purl.obolibrary.org/obo/PLANA_0002118 epithelium An epithelial monolayer lining the pharynx pouch cavity. http://purl.obolibrary.org/obo/PLANA_0002141 sperm duct epithelial surface http://purl.obolibrary.org/obo/BSPO_0000005 anatomical surface Epithelial surface lining the sperm duct. http://purl.obolibrary.org/obo/PLANA_0002142 parenchyma http://purl.obolibrary.org/obo/PLANA_0000113 tissue A loosely organized collection of connective tissue and cells, including neoblasts and their immediate progeny, located in the space outside of the organs between the body wall musculature and the gut. http://purl.obolibrary.org/obo/PLANA_0003300 cephalic ganglia primordium http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity This primordium develops into cephalic ganglia http://purl.obolibrary.org/obo/PLANA_0003301 eye primordium http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity This primordium develops into eye http://purl.obolibrary.org/obo/PLANA_0003302 pharynx primordium http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity This primordium develops into pharynx http://purl.obolibrary.org/obo/PLANA_0003303 pigment cup primordium http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity This primordium develops into optic cup http://purl.obolibrary.org/obo/PLANA_0003304 testis primordium http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity This primordium develops into testis http://purl.obolibrary.org/obo/PLANA_0003305 gonad primoridium http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity This primordium develops into gonad http://purl.obolibrary.org/obo/PLANA_0003400 protonephridial lumen http://purl.obolibrary.org/obo/BFO_0000004 independent continuant lumen which is part of the protonephridia http://purl.obolibrary.org/obo/PLANA_0003401 testis lumen http://purl.obolibrary.org/obo/BFO_0000004 independent continuant lumen which is part of the testis http://purl.obolibrary.org/obo/PLANA_0003402 ovary lumen http://purl.obolibrary.org/obo/BFO_0000004 independent continuant lumen which is part of the ovary http://purl.obolibrary.org/obo/PLANA_0003403 flame cell lumen http://purl.obolibrary.org/obo/BFO_0000004 independent continuant lumen which is part of the flame cell http://purl.obolibrary.org/obo/PLANA_0003500 cephalic ganglia progenitor cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A progenitor cell that gives rise to one or more of the cell type(s) in the nervous system. http://purl.obolibrary.org/obo/PLANA_0003501 dorsal epidermis progenitor cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A progenitor cell that gives rise to one or more of the cell type(s) in the dorsal epidermis. http://purl.obolibrary.org/obo/PLANA_0003502 optic cup progenitor cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A progenitor cell that gives rise to optic cup cells of the eye. http://purl.obolibrary.org/obo/PLANA_0003503 ventral epidermis progenitor cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A progenitor cell that gives rise to one or more of the cell type(s) in the epidermis. http://purl.obolibrary.org/obo/PLANA_0003700 dorsal region of head fragment http://purl.obolibrary.org/obo/PLANA_0003701 ventral region of head fragment The dorsal region of a fragment derived from a prepharyngeal amputation encompassing the head. http://purl.obolibrary.org/obo/PLANA_0003701 ventral region of head fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The ventral region of a fragment derived from a prepharyngeal amputation encompassing the head. http://purl.obolibrary.org/obo/PLANA_0003702 anterior region of head fragment http://purl.obolibrary.org/obo/PLANA_0003703 posterior region of head fragment The anterior region of a fragment derived from a prepharyngeal amputation encompassing the head. http://purl.obolibrary.org/obo/PLANA_0003703 posterior region of head fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The posterior region of a fragment derived from a prepharyngeal amputation encompassing the head. http://purl.obolibrary.org/obo/PLANA_0003704 dorsal region of trunk fragment http://purl.obolibrary.org/obo/PLANA_0003705 ventral region of trunk fragment The dorsal region of a fragment derived from pre- and post-pharyngeal amputations, encompassing the pharynx and parapharyngeal region. http://purl.obolibrary.org/obo/PLANA_0003705 ventral region of trunk fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The ventral region of a fragment derived from pre- and post-pharyngeal amputations, encompassing the pharynx and parapharyngeal region. http://purl.obolibrary.org/obo/PLANA_0003706 anterior region of trunk fragment http://purl.obolibrary.org/obo/PLANA_0003707 posterior region of trunk fragment The anterior region of a fragment derived from pre- and post-pharyngeal amputations, encompassing the pharynx and parapharyngeal region. http://purl.obolibrary.org/obo/PLANA_0003707 posterior region of trunk fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The posterior region of a fragment derived from pre- and post-pharyngeal amputations, encompassing the pharynx and parapharyngeal region. http://purl.obolibrary.org/obo/PLANA_0003708 dorsal region of tail fragment http://purl.obolibrary.org/obo/PLANA_0003709 ventral region of tail fragment The dorsal region of a fragment derived from a postpharyngeal amputation encompassing the tail. http://purl.obolibrary.org/obo/PLANA_0003709 ventral region of tail fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The ventral region of a fragment derived from a postpharyngeal amputation encompassing the tail. http://purl.obolibrary.org/obo/PLANA_0003710 anterior region of tail fragment http://purl.obolibrary.org/obo/PLANA_0003711 posterior region of tail fragment The anterior region of a fragment derived from a postpharyngeal amputation encompassing the tail. http://purl.obolibrary.org/obo/PLANA_0003711 posterior region of tail fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The posterior region of a fragment derived from a postpharyngeal amputation encompassing the tail. http://purl.obolibrary.org/obo/PLANA_0003712 dorsal region of prepharyngeal fragment http://purl.obolibrary.org/obo/PLANA_0003713 ventral region of prepharyngeal fragment The dorsal region of a fragment derived from two prepharyngeal amputations, removing the head and posterior regions of the animal. http://purl.obolibrary.org/obo/PLANA_0003713 ventral region of prepharyngeal fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The ventral region of a fragment derived from two prepharyngeal amputations, removing the head and posterior regions of the animal. http://purl.obolibrary.org/obo/PLANA_0003714 anterior region of prepharyngeal fragment http://purl.obolibrary.org/obo/PLANA_0003715 posterior region of prepharyngeal fragment The anterior region of a fragment derived from two prepharyngeal amputations, removing the head and posterior regions of the animal. http://purl.obolibrary.org/obo/PLANA_0003715 posterior region of prepharyngeal fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The posterior region of a fragment derived from two prepharyngeal amputations, removing the head and posterior regions of the animal. http://purl.obolibrary.org/obo/PLANA_0003716 dorsal region of postpharyngeal fragment http://purl.obolibrary.org/obo/PLANA_0003717 ventral region of postpharyngeal fragment The dorsal region of a fragment derived from two postpharyngeal amputations, removing the anterior region and the tail tip. http://purl.obolibrary.org/obo/PLANA_0003717 ventral region of postpharyngeal fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The ventral region of a fragment derived from two postpharyngeal amputations, removing the anterior region and the tail tip. http://purl.obolibrary.org/obo/PLANA_0003718 anterior region of postpharyngeal fragment http://purl.obolibrary.org/obo/PLANA_0003719 posterior region of postpharyngeal fragment The anterior region of a fragment derived from two postpharyngeal amputations, removing the anterior region and the tail tip. http://purl.obolibrary.org/obo/PLANA_0003719 posterior region of postpharyngeal fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The posterior region of a fragment derived from two postpharyngeal amputations, removing the anterior region and the tail tip. http://purl.obolibrary.org/obo/PLANA_0003720 dorsal region of anterior fragment http://purl.obolibrary.org/obo/PLANA_0003721 ventral region of anterior fragment The dorsal region of a fragment encompassing all or part of the anterior region of the animal. http://purl.obolibrary.org/obo/PLANA_0003721 ventral region of anterior fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The ventral region of a fragment encompassing all or part of the anterior region of the animal. http://purl.obolibrary.org/obo/PLANA_0003722 anterior region of anterior fragment http://purl.obolibrary.org/obo/PLANA_0003723 posterior region of anterior fragment The anterior region of a fragment encompassing all or part of the anterior region of the animal. http://purl.obolibrary.org/obo/PLANA_0003723 posterior region of anterior fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The posterior region of a fragment encompassing all or part of the anterior region of the animal. http://purl.obolibrary.org/obo/PLANA_0003724 dorsal region of posterior fragment http://purl.obolibrary.org/obo/PLANA_0003725 ventral region of posterior fragment The dorsal region of a fragment encompassing all or part of the posterior region of the animal. http://purl.obolibrary.org/obo/PLANA_0003725 ventral region of posterior fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The ventral region of a fragment encompassing all or part of the posterior region of the animal. http://purl.obolibrary.org/obo/PLANA_0003726 anterior region of posterior fragment http://purl.obolibrary.org/obo/PLANA_0003727 posterior region of posterior fragment The anterior region of a fragment encompassing all or part of the posterior region of the animal. http://purl.obolibrary.org/obo/PLANA_0003727 posterior region of posterior fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The posterior region of a fragment encompassing all or part of the posterior region of the animal. http://purl.obolibrary.org/obo/PLANA_0003728 dorsal region of lateral fragment http://purl.obolibrary.org/obo/PLANA_0003729 ventral region of lateral fragment The dorsal region of a fragment derived from an amputation parallel to or along any edge, which overlaps the lateral region, dorso-lateral region, ventro-lateral region, antero-lateral margin, lateral margin, ventro-lateral margin, postero-lateral margin, dorso-lateral margin, antero-lateral region, postero-lateral region. http://purl.obolibrary.org/obo/PLANA_0003729 ventral region of lateral fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The ventral region of a fragment derived from an amputation parallel to or along any edge, which overlaps the lateral region, dorso-lateral region, ventro-lateral region, antero-lateral margin, lateral margin, ventro-lateral margin, postero-lateral margin, dorso-lateral margin, antero-lateral region, postero-lateral region. http://purl.obolibrary.org/obo/PLANA_0003730 anterior region of lateral fragment http://purl.obolibrary.org/obo/PLANA_0003731 posterior region of lateral fragment The anterior region of a fragment derived from an amputation parallel to or along any edge, which overlaps the lateral region, dorso-lateral region, ventro-lateral region, antero-lateral margin, lateral margin, ventro-lateral margin, postero-lateral margin, dorso-lateral margin, antero-lateral region, postero-lateral region. http://purl.obolibrary.org/obo/PLANA_0003731 posterior region of lateral fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The posterior region of a fragment derived from an amputation parallel to or along any edge, which overlaps the lateral region, dorso-lateral region, ventro-lateral region, antero-lateral margin, lateral margin, ventro-lateral margin, postero-lateral margin, dorso-lateral margin, antero-lateral region, postero-lateral region. http://purl.obolibrary.org/obo/PLANA_0003732 dorsal region of longitudinal fragment http://purl.obolibrary.org/obo/PLANA_0003733 ventral region of longitudinal fragment The dorsal region of a fragment derived from an amputation parallel to the midline. http://purl.obolibrary.org/obo/PLANA_0003733 ventral region of longitudinal fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The ventral region of a fragment derived from an amputation parallel to the midline. http://purl.obolibrary.org/obo/PLANA_0003734 anterior region of longitudinal fragment http://purl.obolibrary.org/obo/PLANA_0003735 posterior region of longitudinal fragment The anterior region of a fragment derived from an amputation parallel to the midline. http://purl.obolibrary.org/obo/PLANA_0003735 posterior region of longitudinal fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The posterior region of a fragment derived from an amputation parallel to the midline. http://purl.obolibrary.org/obo/PLANA_0003736 dorsal region of plug fragment http://purl.obolibrary.org/obo/PLANA_0003737 ventral region of plug fragment The dorsal region of a 3D piece of tissue, usually though the whole depth of the animal encompassing both dorsal and ventral sides, often made with a biopsy punch. http://purl.obolibrary.org/obo/PLANA_0003737 ventral region of plug fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The ventral region of a 3D piece of tissue, usually though the whole depth of the animal encompassing both dorsal and ventral sides, often made with a biopsy punch. http://purl.obolibrary.org/obo/PLANA_0003738 anterior region of plug fragment http://purl.obolibrary.org/obo/PLANA_0003739 posterior region of plug fragment The anterior region of a 3D piece of tissue, usually though the whole depth of the animal encompassing both dorsal and ventral sides, often made with a biopsy punch. http://purl.obolibrary.org/obo/PLANA_0003739 posterior region of plug fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The posterior region of a 3D piece of tissue, usually though the whole depth of the animal encompassing both dorsal and ventral sides, often made with a biopsy punch. http://purl.obolibrary.org/obo/PLANA_0003740 dorsal region of plug fragment http://purl.obolibrary.org/obo/PLANA_0003741 ventral region of plug fragment The dorsal region of a piece of tissue removed from the lateral margin at any given point that extendes interiorly to more medial structures. http://purl.obolibrary.org/obo/PLANA_0003741 ventral region of plug fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The ventral region of a piece of tissue removed from the lateral margin at any given point that extendes interiorly to more medial structures. http://purl.obolibrary.org/obo/PLANA_0003742 anterior region of wedge fragment http://purl.obolibrary.org/obo/PLANA_0003743 posterior region of wedge fragment The anterior region of a piece of tissue removed from the lateral margin at any given point that extendes interiorly to more medial structures. http://purl.obolibrary.org/obo/PLANA_0003743 posterior region of wedge fragment http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The posterior region of a piece of tissue removed from the lateral margin at any given point that extendes interiorly to more medial structures. http://purl.obolibrary.org/obo/GO_0061983 meiosis II cell cycle process http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes. http://purl.obolibrary.org/obo/PLANA_0007558 fission plane http://purl.obolibrary.org/obo/BSPO_0000400 anatomical plane Transverse anatomical plane, located approximately 1-2 mm from the posterior extremity of an adult animal, at which fission occurs. http://purl.obolibrary.org/obo/PLANA_0007546 TrpA+ neural progenitor cell http://purl.obolibrary.org/obo/PLANA_0000012 neural progenitor cell piwi-1+, runt-1+, ap2+ progenitor neoblasts required for production of TrpA+ neurons. http://purl.obolibrary.org/obo/PLANA_0000111 proximal tubule epithelial cell http://purl.obolibrary.org/obo/PLANA_0000106 ciliated epithelial cell Ciliated epithelial cells that assemble into proximal tubules. http://purl.obolibrary.org/obo/PLANA_0000138 Hyman vesicle http://purl.obolibrary.org/obo/PLANA_0002137 intracellular granule PROG-2-5 positive granules that range in size from 0.5um to 1um present in epithelia and epithelia progenitor cells. These are distinct from rhabdites. http://purl.obolibrary.org/obo/PLANA_0000140 anterior region of the whole animal http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Compartment along the anteroposterior axis closer to the head rather than the tail, from the head margin to the esophagus. http://purl.obolibrary.org/obo/PLANA_0000141 dorsal region of the whole animal http://purl.obolibrary.org/obo/PLANA_0000143 ventral region of the whole animal Three dimensional compartment along the dorsoventral axis that is above the anteroposterior axis, containing the eyes. http://purl.obolibrary.org/obo/PLANA_0000142 posterior compartment of the whole animal http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Three dimensional compartment along the anteroposterior axis that is closer to the tail rather than the head, from the anterior boundary of the pharyngeal pouch to the tip of the tail. http://purl.obolibrary.org/obo/PLANA_0000143 ventral region of the whole animal http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Compartment along the dorsoventral axis that is below the anteroposterior axis. http://purl.obolibrary.org/obo/GO_0000002 mitochondrial genome maintenance http://purl.obolibrary.org/obo/GO_0007005 mitochondrion organization The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome. http://purl.obolibrary.org/obo/GO_0000003 reproduction http://purl.obolibrary.org/obo/GO_0008150 biological_process The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms. http://purl.obolibrary.org/obo/GO_0000022 mitotic spindle elongation http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B. http://purl.obolibrary.org/obo/GO_0000045 autophagosome assembly http://purl.obolibrary.org/obo/GO_1905037 autophagosome organization The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm. http://purl.obolibrary.org/obo/GO_0000070 mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets. http://purl.obolibrary.org/obo/GO_0000080 mitotic G1 phase http://purl.obolibrary.org/obo/GO_0051318 G1 phase The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis. http://purl.obolibrary.org/obo/GO_0000084 mitotic S phase http://purl.obolibrary.org/obo/GO_0051320 S phase The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle. http://purl.obolibrary.org/obo/GO_0000085 mitotic G2 phase http://purl.obolibrary.org/obo/GO_0051319 G2 phase The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis. http://purl.obolibrary.org/obo/GO_0000087 mitotic M phase http://purl.obolibrary.org/obo/GO_0098763 mitotic cell cycle phase A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle. http://purl.obolibrary.org/obo/GO_0000088 mitotic prophase http://purl.obolibrary.org/obo/GO_0051324 prophase The cell cycle phase which is the first stage of M phase of mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell. http://purl.obolibrary.org/obo/GO_0000089 mitotic metaphase http://purl.obolibrary.org/obo/GO_0051323 metaphase The cell cycle phase, following prophase, during which chromosomes become aligned on the equatorial plate of the cell as part of a mitotic cell cycle. http://purl.obolibrary.org/obo/GO_0000090 mitotic anaphase http://purl.obolibrary.org/obo/GO_0051322 anaphase The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of a mitotic cell cycle. http://purl.obolibrary.org/obo/GO_0000093 mitotic telophase http://purl.obolibrary.org/obo/GO_0051326 telophase The cell cycle phase which follows anaphase during M phase of mitosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. http://purl.obolibrary.org/obo/GO_0000122 negative regulation of transcription by RNA polymerase II http://purl.obolibrary.org/obo/GO_0045892 negative regulation of transcription, DNA-templated Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. http://purl.obolibrary.org/obo/GO_0000212 meiotic spindle organization http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization http://purl.obolibrary.org/obo/GO_0007017 microtubule-based process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. http://purl.obolibrary.org/obo/GO_0000237 leptotene http://purl.obolibrary.org/obo/GO_0098764 meiosis I cell cycle phase The cell cycle phase which is the first stage of prophase I in meiosis, and during which the chromosomes first become visible. http://purl.obolibrary.org/obo/GO_0000238 zygotene http://purl.obolibrary.org/obo/GO_0098764 meiosis I cell cycle phase The cell cycle phase which follows leptotene during prophase I of meiosis, and during which each chromosome pairs with its homolog; the two become aligned and crossing over may occur. http://purl.obolibrary.org/obo/GO_0000239 pachytene http://purl.obolibrary.org/obo/GO_0098764 meiosis I cell cycle phase The cell cycle phase which follows zygotene during prophase I of meiosis, and during which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome. http://purl.obolibrary.org/obo/GO_0000240 diplotene http://purl.obolibrary.org/obo/GO_0098764 meiosis I cell cycle phase The cell cycle phase which follows pachytene during prophase I of meiosis, during which the homologous chromosomes begin to separate and the synaptonemal complex dissolves. http://purl.obolibrary.org/obo/GO_0000241 diakinesis http://purl.obolibrary.org/obo/GO_0098764 meiosis I cell cycle phase The cell cycle phase which follows diplotene during prophase I of meiosis, the separation of homologous chromosomes is complete and crossing over has occurred. http://purl.obolibrary.org/obo/GO_0000278 mitotic cell cycle http://purl.obolibrary.org/obo/GO_0007049 cell cycle Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent. http://purl.obolibrary.org/obo/GO_0000279 M phase http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase. http://purl.obolibrary.org/obo/GO_0000280 nuclear division http://purl.obolibrary.org/obo/GO_0048285 organelle fission The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei. http://purl.obolibrary.org/obo/GO_0000323 lytic vacuole http://purl.obolibrary.org/obo/GO_0005773 vacuole A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases. http://purl.obolibrary.org/obo/GO_0000819 sister chromatid segregation http://purl.obolibrary.org/obo/GO_0098813 nuclear chromosome segregation The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/GO_0000959 mitochondrial RNA metabolic process http://purl.obolibrary.org/obo/GO_0016070 RNA metabolic process The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion. http://purl.obolibrary.org/obo/GO_0001101 response to acid chemical http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. http://purl.obolibrary.org/obo/GO_0001523 retinoid metabolic process http://purl.obolibrary.org/obo/GO_0016101 diterpenoid metabolic process The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity. http://purl.obolibrary.org/obo/GO_0001525 angiogenesis http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. http://purl.obolibrary.org/obo/GO_0001539 cilium or flagellum-dependent cell motility http://purl.obolibrary.org/obo/GO_0048870 cell motility Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella. http://purl.obolibrary.org/obo/GO_0001558 regulation of cell growth http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate, extent or direction of cell growth. http://purl.obolibrary.org/obo/GO_0001560 regulation of cell growth by extracellular stimulus http://purl.obolibrary.org/obo/GO_0001558 regulation of cell growth Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time. http://purl.obolibrary.org/obo/GO_0001568 blood vessel development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood. http://purl.obolibrary.org/obo/GO_0001578 microtubule bundle formation http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization A process that results in a parallel arrangement of microtubules. http://purl.obolibrary.org/obo/GO_0001661 conditioned taste aversion http://purl.obolibrary.org/obo/GO_0008306 associative learning A conditioned aversion to a specific chemical compound as a result of that compound being coupled with a noxious stimulus. http://purl.obolibrary.org/obo/GO_0001675 acrosome assembly http://purl.obolibrary.org/obo/GO_0070925 organelle assembly The formation of the acrosome from the spermatid Golgi. http://purl.obolibrary.org/obo/GO_0001775 cell activation http://purl.obolibrary.org/obo/GO_0009987 cellular process A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/GO_0001896 autolysis http://purl.obolibrary.org/obo/GO_0012501 programmed cell death A programmed cell death process observed in bacteria and filamentous fungi and leading to spontaneous death by lysis. Examples are lysis of the mother cell during sporulation of Bacillus subtilis and self-degradation of fungal cells in Aspergillus nidulans. Autolysis is also involved in bacterial biofilm formation. http://purl.obolibrary.org/obo/GO_0001906 cell killing http://purl.obolibrary.org/obo/GO_0009987 cellular process Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions. http://purl.obolibrary.org/obo/GO_0001907 killing by symbiont of host cells http://purl.obolibrary.org/obo/GO_0051701 interaction with host Any process mediated by an organism that results in the death of cells in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0001932 regulation of protein phosphorylation http://purl.obolibrary.org/obo/GO_0042325 regulation of phosphorylation Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein. http://purl.obolibrary.org/obo/GO_0001933 negative regulation of protein phosphorylation http://purl.obolibrary.org/obo/GO_0042326 negative regulation of phosphorylation Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein. http://purl.obolibrary.org/obo/GO_0001934 positive regulation of protein phosphorylation http://purl.obolibrary.org/obo/GO_0042327 positive regulation of phosphorylation Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein. http://purl.obolibrary.org/obo/GO_0001944 vasculature development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism. http://purl.obolibrary.org/obo/GO_0002246 wound healing involved in inflammatory response http://purl.obolibrary.org/obo/GO_0042060 wound healing The series of events that restore integrity to damaged tissue that contribute to an inflammatory response. http://purl.obolibrary.org/obo/GO_0002250 adaptive immune response http://purl.obolibrary.org/obo/GO_0006955 immune response An immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory). http://purl.obolibrary.org/obo/GO_0002252 immune effector process http://purl.obolibrary.org/obo/GO_0002376 immune system process Any process of the immune system that can potentially contribute to an immune response. http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0002263 cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0002252 immune effector process A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002269 leukocyte activation involved in inflammatory response http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response. http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/GO_0002275 myeloid cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0002366 leukocyte activation involved in immune response A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002281 macrophage activation involved in immune response http://purl.obolibrary.org/obo/GO_0042116 macrophage activation A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002285 lymphocyte activation involved in immune response http://purl.obolibrary.org/obo/GO_0046649 lymphocyte activation A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002323 natural killer cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0030101 natural killer cell activation The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002366 leukocyte activation involved in immune response http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002376 immune system process http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats. http://purl.obolibrary.org/obo/GO_0002437 inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0006955 immune response An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes. http://purl.obolibrary.org/obo/GO_0002438 acute inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0002526 acute inflammatory response An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response. http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002252 immune effector process Any process involved in the carrying out of an immune response by a leukocyte. http://purl.obolibrary.org/obo/GO_0002444 myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity Any process involved in the carrying out of an immune response by a myeloid leukocyte. http://purl.obolibrary.org/obo/GO_0002445 type II hypersensitivity http://purl.obolibrary.org/obo/GO_0016064 immunoglobulin mediated immune response An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors. http://purl.obolibrary.org/obo/GO_0002449 lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity Any process involved in the carrying out of an immune response by a lymphocyte. http://purl.obolibrary.org/obo/GO_0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains http://purl.obolibrary.org/obo/GO_0002250 adaptive immune response An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus. http://purl.obolibrary.org/obo/GO_0002520 immune system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. http://purl.obolibrary.org/obo/GO_0002524 hypersensitivity http://purl.obolibrary.org/obo/GO_0002438 acute inflammatory response to antigenic stimulus An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system. http://purl.obolibrary.org/obo/GO_0002526 acute inflammatory response http://purl.obolibrary.org/obo/GO_0006954 inflammatory response Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response. http://purl.obolibrary.org/obo/GO_0002673 regulation of acute inflammatory response http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response Any process that modulates the frequency, rate, or extent of an acute inflammatory response. http://purl.obolibrary.org/obo/GO_0002674 negative regulation of acute inflammatory response http://purl.obolibrary.org/obo/GO_0050728 negative regulation of inflammatory response Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response. http://purl.obolibrary.org/obo/GO_0002675 positive regulation of acute inflammatory response http://purl.obolibrary.org/obo/GO_0050729 positive regulation of inflammatory response Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response. http://purl.obolibrary.org/obo/GO_0002682 regulation of immune system process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate, or extent of an immune system process. http://purl.obolibrary.org/obo/GO_0002683 negative regulation of immune system process http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. http://purl.obolibrary.org/obo/GO_0002684 positive regulation of immune system process http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates or increases the frequency, rate, or extent of an immune system process. http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation http://purl.obolibrary.org/obo/GO_0050865 regulation of cell activation Any process that modulates the frequency, rate, or extent of leukocyte activation. http://purl.obolibrary.org/obo/GO_0002695 negative regulation of leukocyte activation http://purl.obolibrary.org/obo/GO_0050866 negative regulation of cell activation Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation. http://purl.obolibrary.org/obo/GO_0002696 positive regulation of leukocyte activation http://purl.obolibrary.org/obo/GO_0050867 positive regulation of cell activation Any process that activates or increases the frequency, rate, or extent of leukocyte activation. http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process http://purl.obolibrary.org/obo/GO_0002682 regulation of immune system process Any process that modulates the frequency, rate, or extent of an immune effector process. http://purl.obolibrary.org/obo/GO_0002698 negative regulation of immune effector process http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process. http://purl.obolibrary.org/obo/GO_0002699 positive regulation of immune effector process http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process Any process that activates or increases the frequency, rate, or extent of an immune effector process. http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002704 negative regulation of leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002705 positive regulation of leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002706 regulation of lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002707 negative regulation of lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002706 regulation of lymphocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002708 positive regulation of lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002706 regulation of lymphocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002712 regulation of B cell mediated immunity http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that modulates the frequency, rate, or extent of B cell mediated immunity. http://purl.obolibrary.org/obo/GO_0002713 negative regulation of B cell mediated immunity http://purl.obolibrary.org/obo/GO_0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity. http://purl.obolibrary.org/obo/GO_0002714 positive regulation of B cell mediated immunity http://purl.obolibrary.org/obo/GO_0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity. http://purl.obolibrary.org/obo/GO_0002790 peptide secretion http://purl.obolibrary.org/obo/GO_0046903 secretion The controlled release of a peptide from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0002791 regulation of peptide secretion http://purl.obolibrary.org/obo/GO_0090087 regulation of peptide transport Any process that modulates the frequency, rate, or extent of peptide secretion. http://purl.obolibrary.org/obo/GO_0002792 negative regulation of peptide secretion http://purl.obolibrary.org/obo/GO_0051048 negative regulation of secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion. http://purl.obolibrary.org/obo/GO_0002793 positive regulation of peptide secretion http://purl.obolibrary.org/obo/GO_0051047 positive regulation of secretion Any process that activates or increases the frequency, rate, or extent of peptide secretion. http://purl.obolibrary.org/obo/GO_0002819 regulation of adaptive immune response http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that modulates the frequency, rate, or extent of an adaptive immune response. http://purl.obolibrary.org/obo/GO_0002820 negative regulation of adaptive immune response http://purl.obolibrary.org/obo/GO_0050777 negative regulation of immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response. http://purl.obolibrary.org/obo/GO_0002821 positive regulation of adaptive immune response http://purl.obolibrary.org/obo/GO_0050778 positive regulation of immune response Any process that activates or increases the frequency, rate, or extent of an adaptive immune response. http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains http://purl.obolibrary.org/obo/GO_0002819 regulation of adaptive immune response Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. http://purl.obolibrary.org/obo/GO_0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. http://purl.obolibrary.org/obo/GO_0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. http://purl.obolibrary.org/obo/GO_0002831 regulation of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate, or extent of a response to biotic stimulus. http://purl.obolibrary.org/obo/GO_0002832 negative regulation of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus. http://purl.obolibrary.org/obo/GO_0002833 positive regulation of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus. http://purl.obolibrary.org/obo/GO_0002861 regulation of inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that modulates the frequency, rate, or extent of an inflammatory response to an antigenic stimulus. http://purl.obolibrary.org/obo/GO_0002862 negative regulation of inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0050777 negative regulation of immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus. http://purl.obolibrary.org/obo/GO_0002863 positive regulation of inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0050778 positive regulation of immune response Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus. http://purl.obolibrary.org/obo/GO_0002864 regulation of acute inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0002861 regulation of inflammatory response to antigenic stimulus Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus. http://purl.obolibrary.org/obo/GO_0002865 negative regulation of acute inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0002864 regulation of acute inflammatory response to antigenic stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus. http://purl.obolibrary.org/obo/GO_0002866 positive regulation of acute inflammatory response to antigenic stimulus http://purl.obolibrary.org/obo/GO_0002864 regulation of acute inflammatory response to antigenic stimulus Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus. http://purl.obolibrary.org/obo/GO_0002883 regulation of hypersensitivity http://purl.obolibrary.org/obo/GO_0002864 regulation of acute inflammatory response to antigenic stimulus Any process that modulates the frequency, rate, or extent of hypersensitivity. http://purl.obolibrary.org/obo/GO_0002884 negative regulation of hypersensitivity http://purl.obolibrary.org/obo/GO_0002883 regulation of hypersensitivity Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity. http://purl.obolibrary.org/obo/GO_0002885 positive regulation of hypersensitivity http://purl.obolibrary.org/obo/GO_0002883 regulation of hypersensitivity Any process that activates or increases the frequency, rate, or extent of hypersensitivity. http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002887 negative regulation of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002888 positive regulation of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002889 regulation of immunoglobulin mediated immune response http://purl.obolibrary.org/obo/GO_0002712 regulation of B cell mediated immunity Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response. http://purl.obolibrary.org/obo/GO_0002890 negative regulation of immunoglobulin mediated immune response http://purl.obolibrary.org/obo/GO_0002889 regulation of immunoglobulin mediated immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response. http://purl.obolibrary.org/obo/GO_0002891 positive regulation of immunoglobulin mediated immune response http://purl.obolibrary.org/obo/GO_0002889 regulation of immunoglobulin mediated immune response Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response. http://purl.obolibrary.org/obo/GO_0002892 regulation of type II hypersensitivity http://purl.obolibrary.org/obo/GO_0002889 regulation of immunoglobulin mediated immune response Any process that modulates the frequency, rate, or extent of type II hypersensitivity. http://purl.obolibrary.org/obo/GO_0002893 negative regulation of type II hypersensitivity http://purl.obolibrary.org/obo/GO_0002892 regulation of type II hypersensitivity Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity. http://purl.obolibrary.org/obo/GO_0002894 positive regulation of type II hypersensitivity http://purl.obolibrary.org/obo/GO_0002892 regulation of type II hypersensitivity Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity. http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction http://purl.obolibrary.org/obo/GO_0032502 developmental process A developmental process in which a progressive change in the state of some part of an organism specifically contributes to its ability to form offspring. http://purl.obolibrary.org/obo/GO_0003008 system process http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective. http://purl.obolibrary.org/obo/GO_0003014 renal system process http://purl.obolibrary.org/obo/GO_0003008 system process A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila). http://purl.obolibrary.org/obo/GO_0003341 cilium movement http://purl.obolibrary.org/obo/GO_0007018 microtubule-based movement The directed, self-propelled movement of a cilium. http://purl.obolibrary.org/obo/GO_0003352 regulation of cilium movement http://purl.obolibrary.org/obo/GO_0060632 regulation of microtubule-based movement Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. http://purl.obolibrary.org/obo/GO_0003353 positive regulation of cilium movement http://purl.obolibrary.org/obo/GO_0051272 positive regulation of cellular component movement Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. http://purl.obolibrary.org/obo/GO_0003354 negative regulation of cilium movement http://purl.obolibrary.org/obo/GO_0051271 negative regulation of cellular component movement Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. http://purl.obolibrary.org/obo/GO_0003674 molecular_function http://purl.obolibrary.org/obo/BFO_0000015 process A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process. http://purl.obolibrary.org/obo/GO_0003676 nucleic acid binding http://purl.obolibrary.org/obo/GO_1901363 heterocyclic compound binding Interacting selectively and non-covalently with any nucleic acid. http://purl.obolibrary.org/obo/GO_0003677 DNA binding http://purl.obolibrary.org/obo/GO_0003676 nucleic acid binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). http://purl.obolibrary.org/obo/GO_0003707 steroid hormone receptor activity http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function. http://purl.obolibrary.org/obo/GO_0003824 catalytic activity http://purl.obolibrary.org/obo/GO_0003674 molecular_function Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. http://purl.obolibrary.org/obo/GO_0004888 transmembrane signaling receptor activity http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction. http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity http://purl.obolibrary.org/obo/GO_0004888 transmembrane signaling receptor activity Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/GO_0005102 signaling receptor binding http://purl.obolibrary.org/obo/GO_0005515 protein binding Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. http://purl.obolibrary.org/obo/GO_0005488 binding http://purl.obolibrary.org/obo/GO_0003674 molecular_function The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. http://purl.obolibrary.org/obo/GO_0005515 protein binding http://purl.obolibrary.org/obo/GO_0005488 binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). http://purl.obolibrary.org/obo/GO_0005622 intracellular http://purl.obolibrary.org/obo/GO_0005575 cellular_component The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. http://purl.obolibrary.org/obo/GO_0005634 nucleus http://purl.obolibrary.org/obo/GO_0044464 obsolete cell part A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. http://purl.obolibrary.org/obo/GO_0005737 cytoplasm http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. http://purl.obolibrary.org/obo/GO_0005739 mitochondrion http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. http://purl.obolibrary.org/obo/GO_0005764 lysosome http://purl.obolibrary.org/obo/GO_0000323 lytic vacuole A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. http://purl.obolibrary.org/obo/GO_0005773 vacuole http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. http://purl.obolibrary.org/obo/GO_0005775 vacuolar lumen http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen The volume enclosed within the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0005783 endoplasmic reticulum http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). http://purl.obolibrary.org/obo/GO_0005819 spindle http://purl.obolibrary.org/obo/GO_0043232 intracellular non-membrane-bounded organelle The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. http://purl.obolibrary.org/obo/GO_0005829 cytosol http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. http://purl.obolibrary.org/obo/GO_0005886 plasma membrane http://purl.obolibrary.org/obo/GO_0016020 membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. http://purl.obolibrary.org/obo/GO_0006259 DNA metabolic process http://purl.obolibrary.org/obo/GO_0090304 nucleic acid metabolic process Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. http://purl.obolibrary.org/obo/GO_0006351 transcription, DNA-templated http://purl.obolibrary.org/obo/GO_0097659 nucleic acid-templated transcription The cellular synthesis of RNA on a template of DNA. http://purl.obolibrary.org/obo/GO_0006355 regulation of transcription, DNA-templated http://purl.obolibrary.org/obo/GO_1903506 regulation of nucleic acid-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. http://purl.obolibrary.org/obo/GO_0006357 regulation of transcription by RNA polymerase II http://purl.obolibrary.org/obo/GO_0006355 regulation of transcription, DNA-templated Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. http://purl.obolibrary.org/obo/GO_0006366 transcription by RNA polymerase II http://purl.obolibrary.org/obo/GO_0006351 transcription, DNA-templated The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). http://purl.obolibrary.org/obo/GO_0006390 mitochondrial transcription http://purl.obolibrary.org/obo/GO_0006351 transcription, DNA-templated The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase. http://purl.obolibrary.org/obo/GO_0006464 cellular protein modification process http://purl.obolibrary.org/obo/GO_0044267 cellular protein metabolic process The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). http://purl.obolibrary.org/obo/GO_0006468 protein phosphorylation http://purl.obolibrary.org/obo/GO_0006464 cellular protein modification process The process of introducing a phosphate group on to a protein. http://purl.obolibrary.org/obo/GO_0006508 proteolysis http://purl.obolibrary.org/obo/GO_0019538 protein metabolic process The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. http://purl.obolibrary.org/obo/GO_0006575 cellular modified amino acid metabolic process http://purl.obolibrary.org/obo/GO_1901564 organonitrogen compound metabolic process The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents. http://purl.obolibrary.org/obo/GO_0006790 sulfur compound metabolic process http://purl.obolibrary.org/obo/GO_0044237 cellular metabolic process The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. http://purl.obolibrary.org/obo/GO_0006886 intracellular protein transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. http://purl.obolibrary.org/obo/GO_0006914 autophagy http://purl.obolibrary.org/obo/GO_0061919 process utilizing autophagic mechanism The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation. http://purl.obolibrary.org/obo/GO_0006915 apoptotic process http://purl.obolibrary.org/obo/GO_0012501 programmed cell death A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. http://purl.obolibrary.org/obo/GO_0006950 response to stress http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_0006952 defense response http://purl.obolibrary.org/obo/GO_0006950 response to stress Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. http://purl.obolibrary.org/obo/GO_0006954 inflammatory response http://purl.obolibrary.org/obo/GO_0006952 defense response The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. http://purl.obolibrary.org/obo/GO_0006955 immune response http://purl.obolibrary.org/obo/GO_0002376 immune system process Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. http://purl.obolibrary.org/obo/GO_0006968 cellular defense response http://purl.obolibrary.org/obo/GO_0006952 defense response A defense response that is mediated by cells. http://purl.obolibrary.org/obo/GO_0006974 cellular response to DNA damage stimulus http://purl.obolibrary.org/obo/GO_0033554 cellular response to stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism. http://purl.obolibrary.org/obo/GO_0006997 nucleus organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus. http://purl.obolibrary.org/obo/GO_0007005 mitochondrion organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components. http://purl.obolibrary.org/obo/GO_0007010 cytoskeleton organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0007017 microtubule-based process http://purl.obolibrary.org/obo/GO_0009987 cellular process Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins. http://purl.obolibrary.org/obo/GO_0007018 microtubule-based movement http://purl.obolibrary.org/obo/GO_0007017 microtubule-based process A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. http://purl.obolibrary.org/obo/GO_0007033 vacuole organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole. http://purl.obolibrary.org/obo/GO_0007049 cell cycle http://purl.obolibrary.org/obo/GO_0009987 cellular process The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. http://purl.obolibrary.org/obo/GO_0007051 spindle organization http://purl.obolibrary.org/obo/GO_0022402 cell cycle process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart. http://purl.obolibrary.org/obo/GO_0007052 mitotic spindle organization http://purl.obolibrary.org/obo/GO_0007051 spindle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle. http://purl.obolibrary.org/obo/GO_0007128 meiotic prophase I http://purl.obolibrary.org/obo/GO_0098764 meiosis I cell cycle phase The cell cycle phase which is the first stage of meiosis I and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell. http://purl.obolibrary.org/obo/GO_0007154 cell communication http://purl.obolibrary.org/obo/GO_0009987 cellular process Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0007155 cell adhesion http://purl.obolibrary.org/obo/GO_0009987 cellular process The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. http://purl.obolibrary.org/obo/GO_0007165 signal transduction http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane. http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling http://purl.obolibrary.org/obo/GO_0023052 signaling Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. http://purl.obolibrary.org/obo/GO_0007275 multicellular organism development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/GO_0007286 spermatid development http://purl.obolibrary.org/obo/GO_0007281 germ cell development The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0007610 behavior http://purl.obolibrary.org/obo/GO_0050896 response to stimulus The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity. http://purl.obolibrary.org/obo/GO_0007623 circadian rhythm http://purl.obolibrary.org/obo/GO_0048511 rhythmic process Any biological process in an organism that recurs with a regularity of approximately 24 hours. http://purl.obolibrary.org/obo/GO_0007631 feeding behavior http://purl.obolibrary.org/obo/GO_0007610 behavior Behavior associated with the intake of food. http://purl.obolibrary.org/obo/GO_0008134 transcription factor binding http://purl.obolibrary.org/obo/GO_0005515 protein binding Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription. http://purl.obolibrary.org/obo/GO_0008150 biological_process http://purl.obolibrary.org/obo/BFO_0000015 process A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. http://purl.obolibrary.org/obo/GO_0008234 cysteine-type peptidase activity http://purl.obolibrary.org/obo/GO_0070011 peptidase activity, acting on L-amino acid peptides Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile. http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation http://purl.obolibrary.org/obo/GO_0009987 cellular process The multiplication or reproduction of cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0008284 positive regulation of cell population proliferation http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the rate or extent of cell proliferation. http://purl.obolibrary.org/obo/GO_0008306 associative learning http://purl.obolibrary.org/obo/GO_0007612 learning Learning by associating a stimulus (the cause) with a particular outcome (the effect). http://purl.obolibrary.org/obo/GO_0008514 organic anion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0008509 anion transmembrane transporter activity Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_1901576 organic substance biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0009306 protein secretion http://purl.obolibrary.org/obo/GO_0035592 establishment of protein localization to extracellular region The controlled release of proteins from a cell. http://purl.obolibrary.org/obo/GO_0009536 plastid http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. http://purl.obolibrary.org/obo/GO_0009595 detection of biotic stimulus http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events in which a biotic stimulus, one caused or produced by a living organism, is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0009605 response to external stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. http://purl.obolibrary.org/obo/GO_0009607 response to biotic stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism. http://purl.obolibrary.org/obo/GO_0009611 response to wounding http://purl.obolibrary.org/obo/GO_0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism. http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis http://purl.obolibrary.org/obo/GO_0032502 developmental process The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. http://purl.obolibrary.org/obo/GO_0009755 hormone-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction A series of molecular signals mediated by the detection of a hormone. http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0009888 tissue development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of signal transduction. http://purl.obolibrary.org/obo/GO_0009967 positive regulation of signal transduction http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates or increases the frequency, rate or extent of signal transduction. http://purl.obolibrary.org/obo/GO_0009968 negative regulation of signal transduction http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction. http://purl.obolibrary.org/obo/GO_0009987 cellular process http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/GO_0010033 response to organic substance http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus. http://purl.obolibrary.org/obo/GO_0010035 response to inorganic substance http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus. http://purl.obolibrary.org/obo/GO_0010467 gene expression http://purl.obolibrary.org/obo/GO_0043170 macromolecule metabolic process The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/GO_0010556 regulation of macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010557 positive regulation of macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010558 negative regulation of macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010604 positive regulation of macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010605 negative regulation of macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010646 regulation of cell communication http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0010927 cellular component assembly involved in morphogenesis http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The cellular component assembly that is part of the initial shaping of the component during its developmental progression. http://purl.obolibrary.org/obo/GO_0012501 programmed cell death http://purl.obolibrary.org/obo/GO_0008219 cell death A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell. http://purl.obolibrary.org/obo/GO_0014075 response to amine http://purl.obolibrary.org/obo/GO_0010243 response to organonitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. http://purl.obolibrary.org/obo/GO_0015630 microtubule cytoskeleton http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins. http://purl.obolibrary.org/obo/GO_0015711 organic anion transport http://purl.obolibrary.org/obo/GO_0071702 organic substance transport The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0015833 peptide transport http://purl.obolibrary.org/obo/GO_0071702 organic substance transport The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0016049 cell growth http://purl.obolibrary.org/obo/GO_0040007 growth The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. http://purl.obolibrary.org/obo/GO_0016050 vesicle organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle. http://purl.obolibrary.org/obo/GO_0016064 immunoglobulin mediated immune response http://purl.obolibrary.org/obo/GO_0019724 B cell mediated immunity An immune response mediated by immunoglobulins, whether cell-bound or in solution. http://purl.obolibrary.org/obo/GO_0016070 RNA metabolic process http://purl.obolibrary.org/obo/GO_0090304 nucleic acid metabolic process The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. http://purl.obolibrary.org/obo/GO_0016101 diterpenoid metabolic process http://purl.obolibrary.org/obo/GO_0006721 terpenoid metabolic process The chemical reactions and pathways involving diterpenoid compounds, terpenoids with four isoprene units. http://purl.obolibrary.org/obo/GO_0016236 macroautophagy http://purl.obolibrary.org/obo/GO_0006914 autophagy The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded. http://purl.obolibrary.org/obo/GO_0016301 kinase activity http://purl.obolibrary.org/obo/GO_0016772 transferase activity, transferring phosphorus-containing groups Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. http://purl.obolibrary.org/obo/GO_0016740 transferase activity http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. http://purl.obolibrary.org/obo/GO_0016787 hydrolase activity http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. http://purl.obolibrary.org/obo/GO_0016874 ligase activity http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. http://purl.obolibrary.org/obo/GO_0016879 ligase activity, forming carbon-nitrogen bonds http://purl.obolibrary.org/obo/GO_0016874 ligase activity Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. http://purl.obolibrary.org/obo/GO_0016881 acid-amino acid ligase activity http://purl.obolibrary.org/obo/GO_0016879 ligase activity, forming carbon-nitrogen bonds Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. http://purl.obolibrary.org/obo/GO_0018130 heterocycle biosynthetic process http://purl.obolibrary.org/obo/GO_0046483 heterocycle metabolic process The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). http://purl.obolibrary.org/obo/GO_0019438 aromatic compound biosynthetic process http://purl.obolibrary.org/obo/GO_0044249 cellular biosynthetic process The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring. http://purl.obolibrary.org/obo/GO_0019724 B cell mediated immunity http://purl.obolibrary.org/obo/GO_0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells. http://purl.obolibrary.org/obo/GO_0019778 Atg12 activating enzyme activity http://purl.obolibrary.org/obo/GO_0008641 ubiquitin-like modifier activating enzyme activity Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond. http://purl.obolibrary.org/obo/GO_0019786 Atg8-specific protease activity http://purl.obolibrary.org/obo/GO_0019783 ubiquitin-like protein-specific protease activity Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier. http://purl.obolibrary.org/obo/GO_0019953 sexual reproduction http://purl.obolibrary.org/obo/GO_0044703 multi-organism reproductive process A reproduction process that creates a new organism by combining the genetic material of two gametes, which may come from two organisms or from a single organism, in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. It occurs both in eukaryotes and prokaryotes: in multicellular eukaryotic organisms, an individual is created anew; in prokaryotes, the initial cell has additional or transformed genetic material. In a process called genetic recombination, genetic material (DNA) originating from two gametes join up so that homologous sequences are aligned with each other, and this is followed by exchange of genetic information. After the new recombinant chromosome is formed, it is passed on to progeny. http://purl.obolibrary.org/obo/GO_0019954 asexual reproduction http://purl.obolibrary.org/obo/GO_0000003 reproduction The biological process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process. http://purl.obolibrary.org/obo/GO_0022402 cell cycle process http://purl.obolibrary.org/obo/GO_0009987 cellular process The cellular process that ensures successive accurate and complete genome replication and chromosome segregation. http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase http://purl.obolibrary.org/obo/GO_0044848 biological phase One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. http://purl.obolibrary.org/obo/GO_0022412 cellular process involved in reproduction in multicellular organism http://purl.obolibrary.org/obo/GO_0022414 reproductive process A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism. http://purl.obolibrary.org/obo/GO_0022414 reproductive process http://purl.obolibrary.org/obo/GO_0008150 biological_process A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis. http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly http://purl.obolibrary.org/obo/GO_0016043 cellular component organization The aggregation, arrangement and bonding together of a cellular component. http://purl.obolibrary.org/obo/GO_0023014 signal transduction by protein phosphorylation http://purl.obolibrary.org/obo/GO_0007165 signal transduction A process in which the transfer of one or more phosphate groups to a substrate transmits a signal to the phosphorylated substrate. http://purl.obolibrary.org/obo/GO_0023051 regulation of signaling http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a signaling process. http://purl.obolibrary.org/obo/GO_0023056 positive regulation of signaling http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates, maintains or increases the frequency, rate or extent of a signaling process. http://purl.obolibrary.org/obo/GO_0023057 negative regulation of signaling http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process. http://purl.obolibrary.org/obo/GO_0030097 hemopoiesis http://purl.obolibrary.org/obo/GO_0048534 hematopoietic or lymphoid organ development The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates. http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages. http://purl.obolibrary.org/obo/GO_0030101 natural killer cell activation http://purl.obolibrary.org/obo/GO_0046649 lymphocyte activation The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0030141 secretory granule http://purl.obolibrary.org/obo/GO_0099503 secretory vesicle A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules. http://purl.obolibrary.org/obo/GO_0030154 cell differentiation http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. http://purl.obolibrary.org/obo/GO_0030155 regulation of cell adhesion http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix. http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron. http://purl.obolibrary.org/obo/GO_0030194 positive regulation of blood coagulation http://purl.obolibrary.org/obo/GO_0030193 regulation of blood coagulation Any process that activates or increases the frequency, rate or extent of blood coagulation. http://purl.obolibrary.org/obo/GO_0030261 chromosome condensation http://purl.obolibrary.org/obo/GO_0006323 DNA packaging The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells. http://purl.obolibrary.org/obo/GO_0030522 intracellular receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction Any series of molecular signals initiated by a ligand binding to an receptor located within a cell. http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a secretory granule. http://purl.obolibrary.org/obo/GO_0030728 ovulation http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process The release of a mature ovum/oocyte from an ovary. http://purl.obolibrary.org/obo/GO_0031175 neuron projection development http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/GO_0031323 regulation of cellular metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. http://purl.obolibrary.org/obo/GO_0031324 negative regulation of cellular metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. http://purl.obolibrary.org/obo/GO_0031325 positive regulation of cellular metabolic process http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. http://purl.obolibrary.org/obo/GO_0031326 regulation of cellular biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. http://purl.obolibrary.org/obo/GO_0031327 negative regulation of cellular biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. http://purl.obolibrary.org/obo/GO_0031328 positive regulation of cellular biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. http://purl.obolibrary.org/obo/GO_0031329 regulation of cellular catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. http://purl.obolibrary.org/obo/GO_0031331 positive regulation of cellular catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. http://purl.obolibrary.org/obo/GO_0031333 negative regulation of protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly. http://purl.obolibrary.org/obo/GO_0031334 positive regulation of protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of protein complex assembly. http://purl.obolibrary.org/obo/GO_0031341 regulation of cell killing http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism. http://purl.obolibrary.org/obo/GO_0031342 negative regulation of cell killing http://purl.obolibrary.org/obo/GO_0031341 regulation of cell killing Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing. http://purl.obolibrary.org/obo/GO_0031343 positive regulation of cell killing http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell killing. http://purl.obolibrary.org/obo/GO_0031348 negative regulation of defense response http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response. http://purl.obolibrary.org/obo/GO_0031349 positive regulation of defense response http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that activates or increases the frequency, rate or extent of a defense response. http://purl.obolibrary.org/obo/GO_0031399 regulation of protein modification process http://purl.obolibrary.org/obo/GO_0032268 regulation of cellular protein metabolic process Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. http://purl.obolibrary.org/obo/GO_0031400 negative regulation of protein modification process http://purl.obolibrary.org/obo/GO_0032269 negative regulation of cellular protein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. http://purl.obolibrary.org/obo/GO_0031401 positive regulation of protein modification process http://purl.obolibrary.org/obo/GO_0032270 positive regulation of cellular protein metabolic process Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle http://purl.obolibrary.org/obo/GO_0097708 intracellular vesicle A vesicle found in the cytoplasm of a cell. http://purl.obolibrary.org/obo/GO_0031640 killing of cells of other organism http://purl.obolibrary.org/obo/GO_0001906 cell killing Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions. http://purl.obolibrary.org/obo/GO_0031667 response to nutrient levels http://purl.obolibrary.org/obo/GO_0009991 response to extracellular stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients. http://purl.obolibrary.org/obo/GO_0031668 cellular response to extracellular stimulus http://purl.obolibrary.org/obo/GO_0009991 response to extracellular stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus. http://purl.obolibrary.org/obo/GO_0031981 nuclear lumen http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen The volume enclosed by the nuclear inner membrane. http://purl.obolibrary.org/obo/GO_0032091 negative regulation of protein binding http://purl.obolibrary.org/obo/GO_0051100 negative regulation of binding Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding. http://purl.obolibrary.org/obo/GO_0032101 regulation of response to external stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to an external stimulus. http://purl.obolibrary.org/obo/GO_0032103 positive regulation of response to external stimulus http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus Any process that activates, maintains or increases the rate of a response to an external stimulus. http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process http://purl.obolibrary.org/obo/GO_0008150 biological_process Any biological process, occurring at the level of a multicellular organism, pertinent to its function. http://purl.obolibrary.org/obo/GO_0032502 developmental process http://purl.obolibrary.org/obo/GO_0008150 biological_process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. http://purl.obolibrary.org/obo/GO_0032774 RNA biosynthetic process http://purl.obolibrary.org/obo/GO_0034654 nucleobase-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication. http://purl.obolibrary.org/obo/GO_0032940 secretion by cell http://purl.obolibrary.org/obo/GO_0046903 secretion The controlled release of a substance by a cell. http://purl.obolibrary.org/obo/GO_0032989 cellular component morphogenesis http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The process in which cellular structures, including whole cells or cell parts, are generated and organized. http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex http://purl.obolibrary.org/obo/GO_0005575 cellular_component A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. http://purl.obolibrary.org/obo/GO_0033363 secretory granule organization http://purl.obolibrary.org/obo/GO_0016050 vesicle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. http://purl.obolibrary.org/obo/GO_0033554 cellular response to stress http://purl.obolibrary.org/obo/GO_0006950 response to stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_0034109 homotypic cell-cell adhesion http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion The attachment of a cell to a second cell of the identical type via adhesion molecules. http://purl.obolibrary.org/obo/GO_0034248 regulation of cellular amide metabolic process http://purl.obolibrary.org/obo/GO_0051171 regulation of nitrogen compound metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides. http://purl.obolibrary.org/obo/GO_0034249 negative regulation of cellular amide metabolic process http://purl.obolibrary.org/obo/GO_0051172 negative regulation of nitrogen compound metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides. http://purl.obolibrary.org/obo/GO_0034250 positive regulation of cellular amide metabolic process http://purl.obolibrary.org/obo/GO_0051173 positive regulation of nitrogen compound metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides. http://purl.obolibrary.org/obo/GO_0034613 cellular protein localization http://purl.obolibrary.org/obo/GO_0070727 cellular macromolecule localization Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. http://purl.obolibrary.org/obo/GO_0035556 intracellular signal transduction http://purl.obolibrary.org/obo/GO_0007165 signal transduction The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity http://purl.obolibrary.org/obo/GO_0060089 molecular transducer activity Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. http://purl.obolibrary.org/obo/GO_0040007 growth http://purl.obolibrary.org/obo/GO_0008150 biological_process The increase in size or mass of an entire organism, a part of an organism or a cell. http://purl.obolibrary.org/obo/GO_0040008 regulation of growth http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development. http://purl.obolibrary.org/obo/GO_0042060 wound healing http://purl.obolibrary.org/obo/GO_0009611 response to wounding The series of events that restore integrity to a damaged tissue, following an injury. http://purl.obolibrary.org/obo/GO_0042116 macrophage activation http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cell proliferation. http://purl.obolibrary.org/obo/GO_0042221 response to chemical http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. http://purl.obolibrary.org/obo/GO_0042325 regulation of phosphorylation http://purl.obolibrary.org/obo/GO_0019220 regulation of phosphate metabolic process Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule. http://purl.obolibrary.org/obo/GO_0042326 negative regulation of phosphorylation http://purl.obolibrary.org/obo/GO_0045936 negative regulation of phosphate metabolic process Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule. http://purl.obolibrary.org/obo/GO_0042327 positive regulation of phosphorylation http://purl.obolibrary.org/obo/GO_0045937 positive regulation of phosphate metabolic process Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule. http://purl.obolibrary.org/obo/GO_0042330 taxis http://purl.obolibrary.org/obo/GO_0040011 locomotion The directed movement of a motile cell or organism in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0042592 homeostatic process http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any biological process involved in the maintenance of an internal steady state. http://purl.obolibrary.org/obo/GO_0042593 glucose homeostasis http://purl.obolibrary.org/obo/GO_0033500 carbohydrate homeostasis Any process involved in the maintenance of an internal steady state of glucose within an organism or cell. http://purl.obolibrary.org/obo/GO_0042645 mitochondrial nucleoid http://purl.obolibrary.org/obo/GO_0009295 nucleoid The region of a mitochondrion to which the DNA is confined. http://purl.obolibrary.org/obo/GO_0042755 eating behavior http://purl.obolibrary.org/obo/GO_0007631 feeding behavior The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue. http://purl.obolibrary.org/obo/GO_0042756 drinking behavior http://purl.obolibrary.org/obo/GO_0007631 feeding behavior The specific behavior of an organism relating to the intake of liquids, especially water. http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death Any process that modulates the occurrence or rate of cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0042995 cell projection http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity A prolongation or process extending from a cell, e.g. a flagellum or axon. http://purl.obolibrary.org/obo/GO_0043207 response to external biotic stimulus http://purl.obolibrary.org/obo/GO_0009607 response to biotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things. http://purl.obolibrary.org/obo/GO_0043226 organelle http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0043232 intracellular non-membrane-bounded organelle http://purl.obolibrary.org/obo/GO_0043228 non-membrane-bounded organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes. http://purl.obolibrary.org/obo/GO_0043254 regulation of protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of protein complex assembly. http://purl.obolibrary.org/obo/GO_0043401 steroid hormone mediated signaling pathway http://purl.obolibrary.org/obo/GO_0009755 hormone-mediated signaling pathway A series of molecular signals mediated by a steroid hormone binding to a receptor. http://purl.obolibrary.org/obo/GO_0043414 macromolecule methylation http://purl.obolibrary.org/obo/GO_0044260 cellular macromolecule metabolic process The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule. http://purl.obolibrary.org/obo/GO_0043436 oxoacid metabolic process http://purl.obolibrary.org/obo/GO_0006082 organic acid metabolic process The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). http://purl.obolibrary.org/obo/GO_0043603 cellular amide metabolic process http://purl.obolibrary.org/obo/GO_0034641 cellular nitrogen compound metabolic process The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells. http://purl.obolibrary.org/obo/GO_0043900 regulation of multi-organism process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species. http://purl.obolibrary.org/obo/GO_0043902 positive regulation of multi-organism process http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates or increases the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species. http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex subunit organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex. http://purl.obolibrary.org/obo/GO_0044237 cellular metabolic process http://purl.obolibrary.org/obo/GO_0009987 cellular process The chemical reactions and pathways by which individual cells transform chemical substances. http://purl.obolibrary.org/obo/GO_0044271 cellular nitrogen compound biosynthetic process http://purl.obolibrary.org/obo/GO_0044249 cellular biosynthetic process The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds. http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule. http://purl.obolibrary.org/obo/GO_0044703 multi-organism reproductive process http://purl.obolibrary.org/obo/GO_0051704 multi-organism process A biological process that directly contributes to the process of producing new individuals, involving another organism. http://purl.obolibrary.org/obo/GO_0044764 multi-organism cellular process http://purl.obolibrary.org/obo/GO_0051704 multi-organism process Any process that is carried out at the cellular level which involves another organism of the same or different species. http://purl.obolibrary.org/obo/GO_0044848 biological phase http://purl.obolibrary.org/obo/GO_0008150 biological_process A distinct period or stage in a biological process or cycle. http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation http://purl.obolibrary.org/obo/GO_0002376 immune system process A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0045637 regulation of myeloid cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of myeloid cell differentiation. http://purl.obolibrary.org/obo/GO_0045638 negative regulation of myeloid cell differentiation http://purl.obolibrary.org/obo/GO_1903707 negative regulation of hemopoiesis Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation. http://purl.obolibrary.org/obo/GO_0045639 positive regulation of myeloid cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation. http://purl.obolibrary.org/obo/GO_0045744 negative regulation of G protein-coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0008277 regulation of G protein-coupled receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway. http://purl.obolibrary.org/obo/GO_0045786 negative regulation of cell cycle http://purl.obolibrary.org/obo/GO_0051726 regulation of cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle. http://purl.obolibrary.org/obo/GO_0045839 negative regulation of mitotic nuclear division http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother. http://purl.obolibrary.org/obo/GO_0045892 negative regulation of transcription, DNA-templated http://purl.obolibrary.org/obo/GO_1903507 negative regulation of nucleic acid-templated transcription Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. http://purl.obolibrary.org/obo/GO_0045893 positive regulation of transcription, DNA-templated http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. http://purl.obolibrary.org/obo/GO_0045944 positive regulation of transcription by RNA polymerase II http://purl.obolibrary.org/obo/GO_0045893 positive regulation of transcription, DNA-templated Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. http://purl.obolibrary.org/obo/GO_0045995 regulation of embryonic development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of embryonic development. http://purl.obolibrary.org/obo/GO_0046483 heterocycle metabolic process http://purl.obolibrary.org/obo/GO_0044237 cellular metabolic process The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). http://purl.obolibrary.org/obo/GO_0046649 lymphocyte activation http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0046903 secretion http://purl.obolibrary.org/obo/GO_0006810 transport The controlled release of a substance by a cell or a tissue. http://purl.obolibrary.org/obo/GO_0047484 regulation of response to osmotic stress http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress Any process that modulates the rate or extent of the response to osmotic stress. http://purl.obolibrary.org/obo/GO_0048209 regulation of vesicle targeting, to, from or within Golgi http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0048285 organelle fission http://purl.obolibrary.org/obo/GO_0006996 organelle organization The creation of two or more organelles by division of one organelle. http://purl.obolibrary.org/obo/GO_0048468 cell development http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0048469 cell maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0048513 animal organ development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0048514 blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0035239 tube morphogenesis The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood. http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. http://purl.obolibrary.org/obo/GO_0048589 developmental growth http://purl.obolibrary.org/obo/GO_0040007 growth The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. http://purl.obolibrary.org/obo/GO_0048599 oocyte development http://purl.obolibrary.org/obo/GO_0007281 germ cell development The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis http://purl.obolibrary.org/obo/GO_0032502 developmental process The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. http://purl.obolibrary.org/obo/GO_0048666 neuron development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0048699 generation of neurons http://purl.obolibrary.org/obo/GO_0022008 neurogenesis The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons. http://purl.obolibrary.org/obo/GO_0048731 system development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development http://purl.obolibrary.org/obo/GO_0032502 developmental process The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process http://purl.obolibrary.org/obo/GO_0032502 developmental process A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. http://purl.obolibrary.org/obo/GO_0048870 cell motility http://purl.obolibrary.org/obo/GO_0040011 locomotion Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another. http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells http://purl.obolibrary.org/obo/GO_0042592 homeostatic process Any biological process involved in the maintenance of the steady-state number of cells within a population of cells. http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances. http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of epithelial cell proliferation. http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that activates or increases the rate or extent of epithelial cell proliferation. http://purl.obolibrary.org/obo/GO_0050680 negative regulation of epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation. http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. http://purl.obolibrary.org/obo/GO_0050728 negative regulation of inflammatory response http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response. http://purl.obolibrary.org/obo/GO_0050729 positive regulation of inflammatory response http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response Any process that activates or increases the frequency, rate or extent of the inflammatory response. http://purl.obolibrary.org/obo/GO_0050769 positive regulation of neurogenesis http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system. http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. http://purl.obolibrary.org/obo/GO_0050777 negative regulation of immune response http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. http://purl.obolibrary.org/obo/GO_0050778 positive regulation of immune response http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/GO_0050865 regulation of cell activation http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/GO_0050866 negative regulation of cell activation http://purl.obolibrary.org/obo/GO_0050865 regulation of cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation. http://purl.obolibrary.org/obo/GO_0050867 positive regulation of cell activation http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of activation. http://purl.obolibrary.org/obo/GO_0050877 nervous system process http://purl.obolibrary.org/obo/GO_0003008 system process A organ system process carried out by any of the organs or tissues of neurological system. http://purl.obolibrary.org/obo/GO_0050878 regulation of body fluid levels http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the levels of body fluids. http://purl.obolibrary.org/obo/GO_0050913 sensory perception of bitter taste http://purl.obolibrary.org/obo/GO_0050909 sensory perception of taste The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_0051046 regulation of secretion http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0051047 positive regulation of secretion http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0051048 negative regulation of secretion http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0051052 regulation of DNA metabolic process http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA. http://purl.obolibrary.org/obo/GO_0051093 negative regulation of developmental process http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/GO_0051094 positive regulation of developmental process http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. http://purl.obolibrary.org/obo/GO_0051231 spindle elongation http://purl.obolibrary.org/obo/GO_0022402 cell cycle process The cell cycle process in which the distance is lengthened between poles of the spindle. http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. http://purl.obolibrary.org/obo/GO_0051252 regulation of RNA metabolic process http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA. http://purl.obolibrary.org/obo/GO_0051254 positive regulation of RNA metabolic process http://purl.obolibrary.org/obo/GO_0045935 positive regulation of nucleobase-containing compound metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA. http://purl.obolibrary.org/obo/GO_0051271 negative regulation of cellular component movement http://purl.obolibrary.org/obo/GO_0051270 regulation of cellular component movement Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a cellular component. http://purl.obolibrary.org/obo/GO_0051272 positive regulation of cellular component movement http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of the movement of a cellular component. http://purl.obolibrary.org/obo/GO_0051276 chromosome organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome. http://purl.obolibrary.org/obo/GO_0051301 cell division http://purl.obolibrary.org/obo/GO_0009987 cellular process The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells. http://purl.obolibrary.org/obo/GO_0051318 G1 phase http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis. http://purl.obolibrary.org/obo/GO_0051319 G2 phase http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis). http://purl.obolibrary.org/obo/GO_0051320 S phase http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase The cell cycle phase, following G1, during which DNA synthesis takes place. http://purl.obolibrary.org/obo/GO_0051321 meiotic cell cycle http://purl.obolibrary.org/obo/GO_0022414 reproductive process Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. http://purl.obolibrary.org/obo/GO_0051322 anaphase http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle. http://purl.obolibrary.org/obo/GO_0051323 metaphase http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell. http://purl.obolibrary.org/obo/GO_0051324 prophase http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell. http://purl.obolibrary.org/obo/GO_0051326 telophase http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. http://purl.obolibrary.org/obo/GO_0051329 mitotic interphase http://purl.obolibrary.org/obo/GO_0098763 mitotic cell cycle phase The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs. http://purl.obolibrary.org/obo/GO_0051493 regulation of cytoskeleton organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0051705 obsolete multi-organism behavior http://purl.obolibrary.org/obo/GO_0051704 multi-organism process OBSOLETE. Any process in which an organism has a behavioral effect on another organism of the same or different species. http://purl.obolibrary.org/obo/GO_0051707 response to other organism http://purl.obolibrary.org/obo/GO_0044419 interspecies interaction between organisms Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism. http://purl.obolibrary.org/obo/GO_0051726 regulation of cell cycle http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the rate or extent of progression through the cell cycle. http://purl.obolibrary.org/obo/GO_0051883 killing of cells in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0044419 interspecies interaction between organisms Any process mediated by an organism that results in the death of cells in a second organism, where the two organisms are in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0055082 cellular chemical homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis Any biological process involved in the maintenance of an internal steady state of a chemical at the level of the cell. http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0060560 developmental growth involved in morphogenesis http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape. http://purl.obolibrary.org/obo/GO_0060561 apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1902742 apoptotic process involved in development Any apoptotic process that contributes to the shaping of an anatomical structure. http://purl.obolibrary.org/obo/GO_0060632 regulation of microtubule-based movement http://purl.obolibrary.org/obo/GO_0032886 regulation of microtubule-based process Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0060759 regulation of response to cytokine stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus. http://purl.obolibrary.org/obo/GO_0060760 positive regulation of response to cytokine stimulus http://purl.obolibrary.org/obo/GO_0060759 regulation of response to cytokine stimulus Any process that increases the rate, frequency, or extent of a response to cytokine stimulus. http://purl.obolibrary.org/obo/GO_0060761 negative regulation of response to cytokine stimulus http://purl.obolibrary.org/obo/GO_0060759 regulation of response to cytokine stimulus Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus. http://purl.obolibrary.org/obo/GO_0061651 Atg12 conjugating enzyme activity http://purl.obolibrary.org/obo/GO_0061650 ubiquitin-like protein conjugating enzyme activity Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y -> Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue. http://purl.obolibrary.org/obo/GO_0061660 Atg12 ligase activity http://purl.obolibrary.org/obo/GO_0061659 ubiquitin-like protein ligase activity Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S --> X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate. http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. http://purl.obolibrary.org/obo/GO_0070011 peptidase activity, acting on L-amino acid peptides http://purl.obolibrary.org/obo/GO_0008233 peptidase activity Catalysis of the hydrolysis of peptide bonds formed between L-amino acids. http://purl.obolibrary.org/obo/GO_0070887 cellular response to chemical stimulus http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. http://purl.obolibrary.org/obo/GO_0070925 organelle assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation http://purl.obolibrary.org/obo/GO_0021700 developmental maturation A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0072349 modified amino acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of modified amino acids from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0072358 cardiovascular system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the cardiovascular system over time, from its formation to the mature structure. The cardiovascular system is the anatomical system that has as its parts the heart and blood vessels. http://purl.obolibrary.org/obo/GO_0080135 regulation of cellular response to stress http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_0090087 regulation of peptide transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0090594 inflammatory response to wounding http://purl.obolibrary.org/obo/GO_0009611 response to wounding The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents. http://purl.obolibrary.org/obo/GO_0097159 organic cyclic compound binding http://purl.obolibrary.org/obo/GO_0005488 binding Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure. http://purl.obolibrary.org/obo/GO_0097190 apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered. http://purl.obolibrary.org/obo/GO_0097659 nucleic acid-templated transcription http://purl.obolibrary.org/obo/GO_0032774 RNA biosynthetic process The cellular synthesis of RNA on a template of nucleic acid (DNA or RNA). http://purl.obolibrary.org/obo/GO_0098588 bounding membrane of organelle http://purl.obolibrary.org/obo/GO_0031090 organelle membrane The lipid bilayer that forms the outer-most layer of an organelle. http://purl.obolibrary.org/obo/GO_0098589 membrane region http://purl.obolibrary.org/obo/GO_0016020 membrane A membrane that is a part of a larger membrane. Examples include the apical region of the plasma membrane of an epithelial cell and the various regions of the endoplasmic reticulum membrane. http://purl.obolibrary.org/obo/GO_0098630 aggregation of unicellular organisms http://purl.obolibrary.org/obo/GO_0098743 cell aggregation The clustering together of unicellular organisms in suspension form aggregates. http://purl.obolibrary.org/obo/GO_0098743 cell aggregation http://purl.obolibrary.org/obo/GO_0009987 cellular process The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation. http://purl.obolibrary.org/obo/GO_0098763 mitotic cell cycle phase http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. http://purl.obolibrary.org/obo/GO_0098764 meiosis I cell cycle phase http://purl.obolibrary.org/obo/GO_0098762 meiotic cell cycle phase A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs. http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex Any protein complex that is part of a membrane. http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex Any protein complex that is part of the plasma membrane. http://purl.obolibrary.org/obo/GO_0098801 regulation of renal system process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system. http://purl.obolibrary.org/obo/GO_0098813 nuclear chromosome segregation http://purl.obolibrary.org/obo/GO_0022402 cell cycle process The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. http://purl.obolibrary.org/obo/GO_1901360 organic cyclic compound metabolic process http://purl.obolibrary.org/obo/GO_0071704 organic substance metabolic process The chemical reactions and pathways involving organic cyclic compound. http://purl.obolibrary.org/obo/GO_1901362 organic cyclic compound biosynthetic process http://purl.obolibrary.org/obo/GO_1901360 organic cyclic compound metabolic process The chemical reactions and pathways resulting in the formation of organic cyclic compound. http://purl.obolibrary.org/obo/GO_1901363 heterocyclic compound binding http://purl.obolibrary.org/obo/GO_0005488 binding Interacting selectively and non-covalently with heterocyclic compound. http://purl.obolibrary.org/obo/GO_1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus http://purl.obolibrary.org/obo/GO_0045944 positive regulation of transcription by RNA polymerase II Any positive regulation of transcription from RNA polymerase II promoter that is involved in cellular response to chemical stimulus. http://purl.obolibrary.org/obo/GO_1901564 organonitrogen compound metabolic process http://purl.obolibrary.org/obo/GO_0071704 organic substance metabolic process The chemical reactions and pathways involving organonitrogen compound. http://purl.obolibrary.org/obo/GO_1901566 organonitrogen compound biosynthetic process http://purl.obolibrary.org/obo/GO_1901564 organonitrogen compound metabolic process The chemical reactions and pathways resulting in the formation of organonitrogen compound. http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus. http://purl.obolibrary.org/obo/GO_1902742 apoptotic process involved in development http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process that is involved in anatomical structure development. http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process http://purl.obolibrary.org/obo/GO_0022414 reproductive process A process that is part of the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process http://purl.obolibrary.org/obo/GO_0022402 cell cycle process A process that is part of the mitotic cell cycle. http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of extracellular matrix organization. http://purl.obolibrary.org/obo/GO_1903054 negative regulation of extracellular matrix organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization. http://purl.obolibrary.org/obo/GO_1903055 positive regulation of extracellular matrix organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of extracellular matrix organization. http://purl.obolibrary.org/obo/GO_1903506 regulation of nucleic acid-templated transcription http://purl.obolibrary.org/obo/GO_2001141 regulation of RNA biosynthetic process Any process that modulates the frequency, rate or extent of nucleic acid-templated transcription. http://purl.obolibrary.org/obo/GO_1903507 negative regulation of nucleic acid-templated transcription http://purl.obolibrary.org/obo/GO_1902679 negative regulation of RNA biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription. http://purl.obolibrary.org/obo/GO_1903530 regulation of secretion by cell http://purl.obolibrary.org/obo/GO_0051046 regulation of secretion Any process that modulates the frequency, rate or extent of secretion by cell. http://purl.obolibrary.org/obo/GO_1903531 negative regulation of secretion by cell http://purl.obolibrary.org/obo/GO_1903530 regulation of secretion by cell Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell. http://purl.obolibrary.org/obo/GO_1903532 positive regulation of secretion by cell http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of secretion by cell. http://purl.obolibrary.org/obo/GO_1903578 regulation of ATP metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of ATP metabolic process. http://purl.obolibrary.org/obo/GO_1904746 negative regulation of apoptotic process involved in development http://purl.obolibrary.org/obo/GO_1904748 regulation of apoptotic process involved in development Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development. http://purl.obolibrary.org/obo/GO_1904747 positive regulation of apoptotic process involved in development http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development. http://purl.obolibrary.org/obo/GO_1904748 regulation of apoptotic process involved in development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of apoptotic process involved in development. http://purl.obolibrary.org/obo/GO_1905037 autophagosome organization http://purl.obolibrary.org/obo/GO_0007033 vacuole organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome. http://purl.obolibrary.org/obo/GO_1905039 carboxylic acid transmembrane transport http://purl.obolibrary.org/obo/GO_0098656 anion transmembrane transport The process in which carboxylic acid is transported across a membrane. http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of multicellular organismal development. http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of animal organ morphogenesis. http://purl.obolibrary.org/obo/GO_2001141 regulation of RNA biosynthetic process http://purl.obolibrary.org/obo/GO_0051252 regulation of RNA metabolic process Any process that modulates the frequency, rate or extent of RNA biosynthetic process. http://purl.obolibrary.org/obo/GO_0018995 host cellular component http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity Any organism in which another organism, especially a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection. http://purl.obolibrary.org/obo/GO_0019216 regulation of lipid metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids. http://purl.obolibrary.org/obo/GO_0019233 sensory perception of pain http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process. http://purl.obolibrary.org/obo/GO_0019777 Atg12 transferase activity http://purl.obolibrary.org/obo/GO_0019787 ubiquitin-like protein transferase activity Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y --> Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages. http://purl.obolibrary.org/obo/GO_0022008 neurogenesis http://purl.obolibrary.org/obo/GO_0030154 cell differentiation Generation of cells within the nervous system. http://purl.obolibrary.org/obo/GO_0022407 regulation of cell-cell adhesion http://purl.obolibrary.org/obo/GO_0030155 regulation of cell adhesion Any process that modulates the frequency, rate or extent of attachment of a cell to another cell. http://purl.obolibrary.org/obo/GO_0022408 negative regulation of cell-cell adhesion http://purl.obolibrary.org/obo/GO_0022407 regulation of cell-cell adhesion Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell. http://purl.obolibrary.org/obo/GO_0022409 positive regulation of cell-cell adhesion http://purl.obolibrary.org/obo/GO_0045785 positive regulation of cell adhesion Any process that activates or increases the rate or extent of cell adhesion to another cell. http://purl.obolibrary.org/obo/GO_0022410 circadian sleep/wake cycle process http://purl.obolibrary.org/obo/GO_0048512 circadian behavior A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm. http://purl.obolibrary.org/obo/GO_0022898 regulation of transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0034762 regulation of transmembrane transport Any process that modulates the frequency, rate or extent of transmembrane transporter activity. http://purl.obolibrary.org/obo/GO_0023019 signal transduction involved in regulation of gene expression http://purl.obolibrary.org/obo/GO_0007165 signal transduction Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another. http://purl.obolibrary.org/obo/GO_0023052 signaling http://purl.obolibrary.org/obo/GO_0008150 biological_process The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered. http://purl.obolibrary.org/obo/GO_0023061 signal release http://purl.obolibrary.org/obo/GO_0032940 secretion by cell The process in which a signal is secreted or discharged into the extracellular medium from a cellular source. http://purl.obolibrary.org/obo/GO_0030030 cell projection organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. http://purl.obolibrary.org/obo/GO_0030075 bacterial thylakoid http://purl.obolibrary.org/obo/GO_0009579 thylakoid A thylakoid that is derived from and attached to, but not necessarily continuous with, the plasma membrane, and is not enclosed in a plastid. It bears the photosynthetic pigments in photosynthetic cyanobacteria. http://purl.obolibrary.org/obo/GO_0030133 transport vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell. http://purl.obolibrary.org/obo/GO_0030162 regulation of proteolysis http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. http://purl.obolibrary.org/obo/GO_0030218 erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation The process in which a myeloid precursor cell acquires specializes features of an erythrocyte. http://purl.obolibrary.org/obo/GO_0030263 apoptotic chromosome condensation http://purl.obolibrary.org/obo/GO_0030261 chromosome condensation The compaction of chromatin during apoptosis. http://purl.obolibrary.org/obo/GO_0030284 estrogen receptor activity http://purl.obolibrary.org/obo/GO_0003707 steroid hormone receptor activity Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function. http://purl.obolibrary.org/obo/GO_0030307 positive regulation of cell growth http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate, extent or direction of cell growth. http://purl.obolibrary.org/obo/GO_0030308 negative regulation of cell growth http://purl.obolibrary.org/obo/GO_0045926 negative regulation of growth Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth. http://purl.obolibrary.org/obo/GO_0030430 host cell cytoplasm http://purl.obolibrary.org/obo/GO_0033646 host intracellular part The cytoplasm of a host cell. http://purl.obolibrary.org/obo/GO_0030431 sleep http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain. http://purl.obolibrary.org/obo/GO_0030545 receptor regulator activity http://purl.obolibrary.org/obo/GO_0098772 molecular function regulator The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is changed. http://purl.obolibrary.org/obo/GO_0030581 symbiont intracellular protein transport in host http://purl.obolibrary.org/obo/GO_0051701 interaction with host The directed movement of a symbiont's proteins within a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0030656 regulation of vitamin metabolic process http://purl.obolibrary.org/obo/GO_0062012 regulation of small molecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane http://purl.obolibrary.org/obo/GO_0012506 vesicle membrane The lipid bilayer surrounding a cytoplasmic vesicle. http://purl.obolibrary.org/obo/GO_0030808 regulation of nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0031326 regulation of cellular biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides. http://purl.obolibrary.org/obo/GO_0030809 negative regulation of nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0045980 negative regulation of nucleotide metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides. http://purl.obolibrary.org/obo/GO_0030810 positive regulation of nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0045981 positive regulation of nucleotide metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides. http://purl.obolibrary.org/obo/GO_0031047 gene silencing by RNA http://purl.obolibrary.org/obo/GO_0016458 gene silencing Any process in which RNA molecules inactivate expression of target genes. http://purl.obolibrary.org/obo/GO_0031049 programmed DNA elimination http://purl.obolibrary.org/obo/GO_0006259 DNA metabolic process The DNA metabolic process in which micronuclear-limited sequences, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the developing macronucleus (anlage) of a ciliate. http://purl.obolibrary.org/obo/GO_0031052 chromosome breakage http://purl.obolibrary.org/obo/GO_0051276 chromosome organization Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage. http://purl.obolibrary.org/obo/GO_0031268 pseudopodium organization http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement. http://purl.obolibrary.org/obo/GO_0031427 response to methotrexate http://purl.obolibrary.org/obo/GO_0014070 response to organic cyclic compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase. http://purl.obolibrary.org/obo/GO_0031503 protein-containing complex localization http://purl.obolibrary.org/obo/GO_0008104 protein localization A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system. http://purl.obolibrary.org/obo/GO_0031645 negative regulation of nervous system process http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process. http://purl.obolibrary.org/obo/GO_0031646 positive regulation of nervous system process http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process Any process that activates or increases the frequency, rate or extent of a neurophysiological process. http://purl.obolibrary.org/obo/GO_0031960 response to corticosteroid http://purl.obolibrary.org/obo/GO_0048545 response to steroid hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids. http://purl.obolibrary.org/obo/GO_0031975 envelope http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers. http://purl.obolibrary.org/obo/GO_0031984 organelle subcompartment http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity A compartment that consists of a lumen and an enclosing membrane, and is part of an organelle. http://purl.obolibrary.org/obo/GO_0031987 locomotion involved in locomotory behavior http://purl.obolibrary.org/obo/GO_0040011 locomotion Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. http://purl.obolibrary.org/obo/GO_0032060 bleb assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses. http://purl.obolibrary.org/obo/GO_0032092 positive regulation of protein binding http://purl.obolibrary.org/obo/GO_0051099 positive regulation of binding Any process that activates or increases the frequency, rate or extent of protein binding. http://purl.obolibrary.org/obo/GO_0032104 regulation of response to extracellular stimulus http://purl.obolibrary.org/obo/GO_0032101 regulation of response to external stimulus Any process that modulates the frequency, rate or extent of a response to an extracellular stimulus. http://purl.obolibrary.org/obo/GO_0032105 negative regulation of response to extracellular stimulus http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an extracellular stimulus. http://purl.obolibrary.org/obo/GO_0032106 positive regulation of response to extracellular stimulus http://purl.obolibrary.org/obo/GO_0032104 regulation of response to extracellular stimulus Any process that activates, maintains or increases the rate of a response to an extracellular stimulus. http://purl.obolibrary.org/obo/GO_0032107 regulation of response to nutrient levels http://purl.obolibrary.org/obo/GO_0032104 regulation of response to extracellular stimulus Any process that modulates the frequency, rate or extent of a response to nutrient levels. http://purl.obolibrary.org/obo/GO_0032109 positive regulation of response to nutrient levels http://purl.obolibrary.org/obo/GO_0032107 regulation of response to nutrient levels Any process that activates or increases the frequency, rate or extent of a response to nutrient levels. http://purl.obolibrary.org/obo/GO_0032270 positive regulation of cellular protein metabolic process http://purl.obolibrary.org/obo/GO_0051247 positive regulation of protein metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate or extent of the directed movement of substances within cells. http://purl.obolibrary.org/obo/GO_0032387 negative regulation of intracellular transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells. http://purl.obolibrary.org/obo/GO_0032388 positive regulation of intracellular transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells. http://purl.obolibrary.org/obo/GO_0032409 regulation of transporter activity http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the activity of a transporter. http://purl.obolibrary.org/obo/GO_0032410 negative regulation of transporter activity http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops or reduces the activity of a transporter. http://purl.obolibrary.org/obo/GO_0032411 positive regulation of transporter activity http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the activity of a transporter. http://purl.obolibrary.org/obo/GO_0032414 positive regulation of ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0032412 regulation of ion transmembrane transporter activity Any process that activates or increases the activity of an ion transporter. http://purl.obolibrary.org/obo/GO_0032468 Golgi calcium ion homeostasis http://purl.obolibrary.org/obo/GO_0006874 cellular calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings. http://purl.obolibrary.org/obo/GO_0032469 endoplasmic reticulum calcium ion homeostasis http://purl.obolibrary.org/obo/GO_0006874 cellular calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings. http://purl.obolibrary.org/obo/GO_0032504 multicellular organism reproduction http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. http://purl.obolibrary.org/obo/GO_0032594 protein transport within lipid bilayer http://purl.obolibrary.org/obo/GO_0051668 localization within membrane The directed movement of a protein from one location to another within a lipid bilayer. http://purl.obolibrary.org/obo/GO_0032814 regulation of natural killer cell activation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that modulates the frequency, rate or extent of natural killer cell activation. http://purl.obolibrary.org/obo/GO_0032815 negative regulation of natural killer cell activation http://purl.obolibrary.org/obo/GO_0051250 negative regulation of lymphocyte activation Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation. http://purl.obolibrary.org/obo/GO_0032816 positive regulation of natural killer cell activation http://purl.obolibrary.org/obo/GO_0051251 positive regulation of lymphocyte activation Any process that activates or increases the frequency, rate or extent of natural killer cell activation. http://purl.obolibrary.org/obo/GO_0032838 plasma membrane bounded cell projection cytoplasm http://purl.obolibrary.org/obo/GO_0099568 cytoplasmic region All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection. http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0032886 regulation of microtubule-based process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton. http://purl.obolibrary.org/obo/GO_0032887 regulation of spindle elongation http://purl.obolibrary.org/obo/GO_0090224 regulation of spindle organization Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle. http://purl.obolibrary.org/obo/GO_0032888 regulation of mitotic spindle elongation http://purl.obolibrary.org/obo/GO_0033047 regulation of mitotic sister chromatid segregation Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle. http://purl.obolibrary.org/obo/GO_0032890 regulation of organic acid transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032891 negative regulation of organic acid transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032892 positive regulation of organic acid transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0033044 regulation of chromosome organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome. http://purl.obolibrary.org/obo/GO_0033046 negative regulation of sister chromatid segregation http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation. http://purl.obolibrary.org/obo/GO_0033048 negative regulation of mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0033047 regulation of mitotic sister chromatid segregation Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis. http://purl.obolibrary.org/obo/GO_0033142 progesterone receptor binding http://purl.obolibrary.org/obo/GO_0016922 nuclear receptor binding Interacting selectively and non-covalently with a progesterone receptor. http://purl.obolibrary.org/obo/GO_0033157 regulation of intracellular protein transport http://purl.obolibrary.org/obo/GO_1903827 regulation of cellular protein localization Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells. http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle http://purl.obolibrary.org/obo/GO_0034613 cellular protein localization A process in which a protein is transported to, or maintained in, a location within an organelle. http://purl.obolibrary.org/obo/GO_0033371 T cell secretory granule organization http://purl.obolibrary.org/obo/GO_0033363 secretory granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. http://purl.obolibrary.org/obo/GO_0033500 carbohydrate homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell. http://purl.obolibrary.org/obo/GO_0033576 protein glycosylation in cytosol http://purl.obolibrary.org/obo/GO_0006486 protein glycosylation The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the cytosol. http://purl.obolibrary.org/obo/GO_0033577 protein glycosylation in endoplasmic reticulum http://purl.obolibrary.org/obo/GO_0006486 protein glycosylation The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the endoplasmic reticulum. http://purl.obolibrary.org/obo/GO_0033578 protein glycosylation in Golgi http://purl.obolibrary.org/obo/GO_0006486 protein glycosylation The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0033635 modulation by symbiont of host response to abiotic stimulus http://purl.obolibrary.org/obo/GO_0044003 modulation by symbiont of host process Any process in which an organism modulates a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0033636 modulation by symbiont of host response to temperature stimulus http://purl.obolibrary.org/obo/GO_0033635 modulation by symbiont of host response to abiotic stimulus Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0033640 modulation by symbiont of host response to osmotic stress http://purl.obolibrary.org/obo/GO_0033635 modulation by symbiont of host response to abiotic stimulus Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0033641 modulation by symbiont of host response to pH http://purl.obolibrary.org/obo/GO_0033635 modulation by symbiont of host response to abiotic stimulus Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0033643 host cell part http://purl.obolibrary.org/obo/GO_0018995 host cellular component Any constituent part of a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0033646 host intracellular part http://purl.obolibrary.org/obo/GO_0033643 host cell part Any constituent part of the living contents of a host cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0033647 host intracellular organelle http://purl.obolibrary.org/obo/GO_0033646 host intracellular part Organized structure of distinctive morphology and function, occurring within the host cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0033648 host intracellular membrane-bounded organelle http://purl.obolibrary.org/obo/GO_0033647 host intracellular organelle Organized structure of distinctive morphology and function, as found in host cells, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0033668 negative regulation by symbiont of host apoptotic process http://purl.obolibrary.org/obo/GO_0052150 modulation by symbiont of host apoptotic process Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0033674 positive regulation of kinase activity http://purl.obolibrary.org/obo/GO_0051347 positive regulation of transferase activity Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. http://purl.obolibrary.org/obo/GO_0034097 response to cytokine http://purl.obolibrary.org/obo/GO_0010033 response to organic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus. http://purl.obolibrary.org/obo/GO_0034101 erythrocyte homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis Any process of regulating the production and elimination of erythrocytes within an organism. http://purl.obolibrary.org/obo/GO_0034110 regulation of homotypic cell-cell adhesion http://purl.obolibrary.org/obo/GO_0022407 regulation of cell-cell adhesion Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion. http://purl.obolibrary.org/obo/GO_0034111 negative regulation of homotypic cell-cell adhesion http://purl.obolibrary.org/obo/GO_0034110 regulation of homotypic cell-cell adhesion Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion. http://purl.obolibrary.org/obo/GO_0034112 positive regulation of homotypic cell-cell adhesion http://purl.obolibrary.org/obo/GO_0034110 regulation of homotypic cell-cell adhesion Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion. http://purl.obolibrary.org/obo/GO_0034762 regulation of transmembrane transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0034766 negative regulation of ion transmembrane transport http://purl.obolibrary.org/obo/GO_0043271 negative regulation of ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0034767 positive regulation of ion transmembrane transport http://purl.obolibrary.org/obo/GO_0043270 positive regulation of ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0035258 steroid hormone receptor binding http://purl.obolibrary.org/obo/GO_0035257 nuclear hormone receptor binding Interacting selectively and non-covalently with a steroid hormone receptor. http://purl.obolibrary.org/obo/GO_0040011 locomotion http://purl.obolibrary.org/obo/GO_0008150 biological_process Self-propelled movement of a cell or organism from one location to another. http://purl.obolibrary.org/obo/GO_0040020 regulation of meiotic nuclear division http://purl.obolibrary.org/obo/GO_0051445 regulation of meiotic cell cycle Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes. http://purl.obolibrary.org/obo/GO_0042025 host cell nucleus http://purl.obolibrary.org/obo/GO_0033648 host intracellular membrane-bounded organelle A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0042745 circadian sleep/wake cycle http://purl.obolibrary.org/obo/GO_0048512 circadian behavior The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm. http://purl.obolibrary.org/obo/GO_0043062 extracellular structure organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite. http://purl.obolibrary.org/obo/GO_0043069 negative regulation of programmed cell death http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. http://purl.obolibrary.org/obo/GO_0043227 membrane-bounded organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0043233 organelle lumen http://purl.obolibrary.org/obo/GO_0031974 membrane-enclosed lumen The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen. http://purl.obolibrary.org/obo/GO_0043393 regulation of protein binding http://purl.obolibrary.org/obo/GO_0051098 regulation of binding Any process that modulates the frequency, rate or extent of protein binding. http://purl.obolibrary.org/obo/GO_0043549 regulation of kinase activity http://purl.obolibrary.org/obo/GO_0051338 regulation of transferase activity Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. http://purl.obolibrary.org/obo/GO_0043656 host intracellular region http://purl.obolibrary.org/obo/GO_0033643 host cell part That space within the plasma membrane of a host cell. http://purl.obolibrary.org/obo/GO_0043657 host cell http://purl.obolibrary.org/obo/GO_0018995 host cellular component A cell within a host organism. Includes the host plasma membrane and any external encapsulating structures such as the host cell wall and cell envelope. http://purl.obolibrary.org/obo/GO_0044003 modulation by symbiont of host process http://purl.obolibrary.org/obo/GO_0051817 modulation of process of other organism involved in symbiotic interaction The process in which a symbiont organism effects a change in the structure or processes of its host organism. http://purl.obolibrary.org/obo/GO_0044057 regulation of system process http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system. http://purl.obolibrary.org/obo/GO_0044068 modulation by symbiont of host cellular process http://purl.obolibrary.org/obo/GO_0044003 modulation by symbiont of host process Any process in which a symbiont organism modulates the frequency, rate or extent of a cellular process, any process that is carried out at the cellular level, but not necessarily restricted to a single cell, in its host organism. http://purl.obolibrary.org/obo/GO_0044088 regulation of vacuole organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. http://purl.obolibrary.org/obo/GO_0044092 negative regulation of molecular function http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. http://purl.obolibrary.org/obo/GO_0044093 positive regulation of molecular function http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. http://purl.obolibrary.org/obo/GO_0044217 other organism part http://purl.obolibrary.org/obo/GO_0005575 cellular_component Any constituent part of a secondary organism with which the first organism is interacting. http://purl.obolibrary.org/obo/GO_0044364 disruption of cells of other organism http://purl.obolibrary.org/obo/GO_0035821 modulation of process of other organism A process in which an organism has a negative effect on the functioning of the second organism's cells. http://purl.obolibrary.org/obo/GO_0044782 cilium organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. http://purl.obolibrary.org/obo/GO_0045202 synapse http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. http://purl.obolibrary.org/obo/GO_0045835 negative regulation of meiotic nuclear division http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis. http://purl.obolibrary.org/obo/GO_0045836 positive regulation of meiotic nuclear division http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of meiosis. http://purl.obolibrary.org/obo/GO_0045840 positive regulation of mitotic nuclear division http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of mitosis. http://purl.obolibrary.org/obo/GO_0045926 negative regulation of growth http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism. http://purl.obolibrary.org/obo/GO_0045927 positive regulation of growth http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism. http://purl.obolibrary.org/obo/GO_0045935 positive regulation of nucleobase-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0051173 positive regulation of nitrogen compound metabolic process Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0045980 negative regulation of nucleotide metabolic process http://purl.obolibrary.org/obo/GO_0045936 negative regulation of phosphate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides. http://purl.obolibrary.org/obo/GO_0045981 positive regulation of nucleotide metabolic process http://purl.obolibrary.org/obo/GO_0045937 positive regulation of phosphate metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides. http://purl.obolibrary.org/obo/GO_0046677 response to antibiotic http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. http://purl.obolibrary.org/obo/GO_0046858 chlorosome http://purl.obolibrary.org/obo/GO_0043232 intracellular non-membrane-bounded organelle A large enclosure of aggregated pigment, typically bacteriochlorophyll c (BChl c), that acts as a light-harvesting antenna structure and is characteristic of green photosynthetic bacteria (e.g. Chlorobiaceae). The BChl aggregates are organized into lamellar elements by pigment-pigment rather than pigment-protein interactions. Chlorosomes also contain BChl a, carotenoids, quinones, lipids, and proteins, and are attached to the cytoplasmic membrane via a BChl a-containing protein baseplate. http://purl.obolibrary.org/obo/GO_0048521 negative regulation of behavior http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. http://purl.obolibrary.org/obo/GO_0048534 hematopoietic or lymphoid organ development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation. http://purl.obolibrary.org/obo/GO_0048545 response to steroid hormone http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. http://purl.obolibrary.org/obo/GO_0048640 negative regulation of developmental growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth. http://purl.obolibrary.org/obo/GO_0050714 positive regulation of protein secretion http://purl.obolibrary.org/obo/GO_0051222 positive regulation of protein transport Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell. http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. http://purl.obolibrary.org/obo/GO_0050818 regulation of coagulation http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass. http://purl.obolibrary.org/obo/GO_0050819 negative regulation of coagulation http://purl.obolibrary.org/obo/GO_0050818 regulation of coagulation Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation. http://purl.obolibrary.org/obo/GO_0050820 positive regulation of coagulation http://purl.obolibrary.org/obo/GO_0050818 regulation of coagulation Any process that activates or increases the frequency, rate or extent of coagulation. http://purl.obolibrary.org/obo/GO_0051054 positive regulation of DNA metabolic process http://purl.obolibrary.org/obo/GO_0045935 positive regulation of nucleobase-containing compound metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA. http://purl.obolibrary.org/obo/GO_0051099 positive regulation of binding http://purl.obolibrary.org/obo/GO_0051098 regulation of binding Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. http://purl.obolibrary.org/obo/GO_0051100 negative regulation of binding http://purl.obolibrary.org/obo/GO_0051098 regulation of binding Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. http://purl.obolibrary.org/obo/GO_0051173 positive regulation of nitrogen compound metabolic process http://purl.obolibrary.org/obo/GO_0051171 regulation of nitrogen compound metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. http://purl.obolibrary.org/obo/GO_0051175 negative regulation of sulfur metabolic process http://purl.obolibrary.org/obo/GO_0042762 regulation of sulfur metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur. http://purl.obolibrary.org/obo/GO_0051179 localization http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. http://purl.obolibrary.org/obo/GO_0051223 regulation of protein transport http://purl.obolibrary.org/obo/GO_0090087 regulation of peptide transport Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process http://purl.obolibrary.org/obo/GO_0051171 regulation of nitrogen compound metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein. http://purl.obolibrary.org/obo/GO_0051247 positive regulation of protein metabolic process http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein. http://purl.obolibrary.org/obo/GO_0051248 negative regulation of protein metabolic process http://purl.obolibrary.org/obo/GO_0051172 negative regulation of nitrogen compound metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein. http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation Any process that modulates the frequency, rate or extent of lymphocyte activation. http://purl.obolibrary.org/obo/GO_0051250 negative regulation of lymphocyte activation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation. http://purl.obolibrary.org/obo/GO_0051251 positive regulation of lymphocyte activation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that activates or increases the frequency, rate or extent of lymphocyte activation. http://purl.obolibrary.org/obo/GO_0051253 negative regulation of RNA metabolic process http://purl.obolibrary.org/obo/GO_0045934 negative regulation of nucleobase-containing compound metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA. http://purl.obolibrary.org/obo/GO_0051347 positive regulation of transferase activity http://purl.obolibrary.org/obo/GO_0051338 regulation of transferase activity Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor. http://purl.obolibrary.org/obo/GO_0051348 negative regulation of transferase activity http://purl.obolibrary.org/obo/GO_0051338 regulation of transferase activity Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor. http://purl.obolibrary.org/obo/GO_0051648 vesicle localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization The directed movement of an organelle to a specific location. http://purl.obolibrary.org/obo/GO_0051668 localization within membrane http://purl.obolibrary.org/obo/GO_0051641 cellular localization Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane. http://purl.obolibrary.org/obo/GO_0051674 localization of cell http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which a cell is transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0051701 interaction with host http://purl.obolibrary.org/obo/GO_0044403 symbiosis, encompassing mutualism through parasitism An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism. http://purl.obolibrary.org/obo/GO_0051781 positive regulation of cell division http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell division. http://purl.obolibrary.org/obo/GO_0051782 negative regulation of cell division http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division Any process that stops, prevents, or reduces the frequency, rate or extent of cell division. http://purl.obolibrary.org/obo/GO_0051960 regulation of nervous system development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. http://purl.obolibrary.org/obo/GO_0051961 negative regulation of nervous system development http://purl.obolibrary.org/obo/GO_0051960 regulation of nervous system development Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. http://purl.obolibrary.org/obo/GO_0051962 positive regulation of nervous system development http://purl.obolibrary.org/obo/GO_0051960 regulation of nervous system development Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. http://purl.obolibrary.org/obo/GO_0051983 regulation of chromosome segregation http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/GO_0051985 negative regulation of chromosome segregation http://purl.obolibrary.org/obo/GO_0051983 regulation of chromosome segregation Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/GO_0052040 modulation by symbiont of host programmed cell death http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052041 negative regulation by symbiont of host programmed cell death http://purl.obolibrary.org/obo/GO_0052040 modulation by symbiont of host programmed cell death Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052150 modulation by symbiont of host apoptotic process http://purl.obolibrary.org/obo/GO_0052433 modulation by organism of apoptotic process in other organism involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052151 positive regulation by symbiont of host apoptotic process http://purl.obolibrary.org/obo/GO_0052042 positive regulation by symbiont of host programmed cell death Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0055062 phosphate ion homeostasis http://purl.obolibrary.org/obo/GO_0072506 trivalent inorganic anion homeostasis Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell. http://purl.obolibrary.org/obo/GO_0055080 cation homeostasis http://purl.obolibrary.org/obo/GO_0050801 ion homeostasis Any process involved in the maintenance of an internal steady state of cations within an organism or cell. http://purl.obolibrary.org/obo/GO_0055083 monovalent inorganic anion homeostasis http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis Any process involved in the maintenance of an internal steady state of monovalent inorganic anions within an organism or cell. http://purl.obolibrary.org/obo/GO_0060236 regulation of mitotic spindle organization http://purl.obolibrary.org/obo/GO_0090224 regulation of spindle organization Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle. http://purl.obolibrary.org/obo/GO_0060968 regulation of gene silencing http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation. http://purl.obolibrary.org/obo/GO_0060969 negative regulation of gene silencing http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression Any process that decreases the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation. http://purl.obolibrary.org/obo/GO_0061041 regulation of wound healing http://purl.obolibrary.org/obo/GO_1903034 regulation of response to wounding Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. http://purl.obolibrary.org/obo/GO_0061045 negative regulation of wound healing http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. http://purl.obolibrary.org/obo/GO_0065010 extracellular membrane-bounded organelle http://purl.obolibrary.org/obo/GO_0043230 extracellular organelle Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell. http://purl.obolibrary.org/obo/GO_0070085 glycosylation http://purl.obolibrary.org/obo/GO_0008152 metabolic process The covalent attachment and further modification of carbohydrate residues to a substrate molecule. http://purl.obolibrary.org/obo/GO_0071310 cellular response to organic substance http://purl.obolibrary.org/obo/GO_0070887 cellular response to chemical stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus. http://purl.obolibrary.org/obo/GO_0071495 cellular response to endogenous stimulus http://purl.obolibrary.org/obo/GO_0009719 response to endogenous stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. http://purl.obolibrary.org/obo/GO_0071496 cellular response to external stimulus http://purl.obolibrary.org/obo/GO_0009605 response to external stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. http://purl.obolibrary.org/obo/GO_0090224 regulation of spindle organization http://purl.obolibrary.org/obo/GO_0070507 regulation of microtubule cytoskeleton organization Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle. http://purl.obolibrary.org/obo/GO_0090303 positive regulation of wound healing http://purl.obolibrary.org/obo/GO_0061041 regulation of wound healing Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. http://purl.obolibrary.org/obo/GO_0097060 synaptic membrane http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. http://purl.obolibrary.org/obo/GO_0097708 intracellular vesicle http://purl.obolibrary.org/obo/GO_0031982 vesicle Any vesicle that is part of the intracellular region. http://purl.obolibrary.org/obo/GO_0097722 sperm motility http://purl.obolibrary.org/obo/GO_0048870 cell motility Any process involved in the controlled movement of a sperm cell. http://purl.obolibrary.org/obo/GO_0098984 neuron to neuron synapse http://purl.obolibrary.org/obo/GO_0045202 synapse A synapse in which pre and post-synaptic cells are neurons. http://purl.obolibrary.org/obo/GO_0099503 secretory vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space. http://purl.obolibrary.org/obo/GO_0099738 cell cortex region http://purl.obolibrary.org/obo/GO_0099568 cytoplasmic region The complete extent of cell cortex that underlies some some region of the plasma membrane http://purl.obolibrary.org/obo/GO_1900046 regulation of hemostasis http://purl.obolibrary.org/obo/GO_0050878 regulation of body fluid levels Any process that modulates the frequency, rate or extent of hemostasis. http://purl.obolibrary.org/obo/GO_1900047 negative regulation of hemostasis http://purl.obolibrary.org/obo/GO_1900046 regulation of hemostasis Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis. http://purl.obolibrary.org/obo/GO_1900048 positive regulation of hemostasis http://purl.obolibrary.org/obo/GO_1900046 regulation of hemostasis Any process that activates or increases the frequency, rate or extent of hemostasis. http://purl.obolibrary.org/obo/GO_1900371 regulation of purine nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_1900542 regulation of purine nucleotide metabolic process Any process that modulates the frequency, rate or extent of purine nucleotide biosynthetic processes. http://purl.obolibrary.org/obo/GO_1900372 negative regulation of purine nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_1900543 negative regulation of purine nucleotide metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes. http://purl.obolibrary.org/obo/GO_1900373 positive regulation of purine nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_1900544 positive regulation of purine nucleotide metabolic process Any process that activates or increases the frequency, rate or extent of purine nucleotide biosynthetic processes. http://purl.obolibrary.org/obo/GO_1900542 regulation of purine nucleotide metabolic process http://purl.obolibrary.org/obo/GO_0006140 regulation of nucleotide metabolic process Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process. http://purl.obolibrary.org/obo/GO_1900543 negative regulation of purine nucleotide metabolic process http://purl.obolibrary.org/obo/GO_1900542 regulation of purine nucleotide metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process. http://purl.obolibrary.org/obo/GO_1900544 positive regulation of purine nucleotide metabolic process http://purl.obolibrary.org/obo/GO_1900542 regulation of purine nucleotide metabolic process Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process. http://purl.obolibrary.org/obo/GO_1901654 response to ketone http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound A response that results in a state of tolerance to ketone. http://purl.obolibrary.org/obo/GO_1902679 negative regulation of RNA biosynthetic process http://purl.obolibrary.org/obo/GO_0051253 negative regulation of RNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process. http://purl.obolibrary.org/obo/GO_1903108 regulation of mitochondrial transcription http://purl.obolibrary.org/obo/GO_0006355 regulation of transcription, DNA-templated Any process that modulates the frequency, rate or extent of transcription occuring in the mitochondrion. http://purl.obolibrary.org/obo/GO_1903353 regulation of nucleus organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of nucleus organization. http://purl.obolibrary.org/obo/GO_1903792 negative regulation of anion transport http://purl.obolibrary.org/obo/GO_0043271 negative regulation of ion transport Any process that stops, prevents or reduces the frequency, rate or extent of anion transport. http://purl.obolibrary.org/obo/GO_1903793 positive regulation of anion transport http://purl.obolibrary.org/obo/GO_0043270 positive regulation of ion transport Any process that activates or increases the frequency, rate or extent of anion transport. http://purl.obolibrary.org/obo/GO_1903827 regulation of cellular protein localization http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. http://purl.obolibrary.org/obo/GO_1905879 regulation of oogenesis http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of oogenesis. http://purl.obolibrary.org/obo/GO_1905880 negative regulation of oogenesis http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis. http://purl.obolibrary.org/obo/GO_1905881 positive regulation of oogenesis http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of oogenesis. http://purl.obolibrary.org/obo/GO_1990904 ribonucleoprotein complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A macromolecular complex containing both protein and RNA molecules. http://purl.obolibrary.org/obo/GO_2000145 regulation of cell motility http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that modulates the frequency, rate or extent of cell motility. http://purl.obolibrary.org/obo/GO_2000146 negative regulation of cell motility http://purl.obolibrary.org/obo/GO_0040013 negative regulation of locomotion Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility. http://purl.obolibrary.org/obo/GO_2000147 positive regulation of cell motility http://purl.obolibrary.org/obo/GO_0040017 positive regulation of locomotion Any process that activates or increases the frequency, rate or extent of cell motility. http://purl.obolibrary.org/obo/GO_2000273 positive regulation of signaling receptor activity http://purl.obolibrary.org/obo/GO_0044093 positive regulation of molecular function Any process that activates or increases the frequency, rate or extent of signaling receptor activity. http://purl.obolibrary.org/obo/GO_2001251 negative regulation of chromosome organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization. http://purl.obolibrary.org/obo/GO_2001252 positive regulation of chromosome organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of chromosome organization. http://purl.obolibrary.org/obo/GO_0034404 nucleobase-containing small molecule biosynthetic process http://purl.obolibrary.org/obo/GO_0034654 nucleobase-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide. http://purl.obolibrary.org/obo/GO_0034763 negative regulation of transmembrane transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0034764 positive regulation of transmembrane transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0035106 operant conditioning http://purl.obolibrary.org/obo/GO_0007612 learning Learning to anticipate future events on the basis of past experience with the consequences of one's own behavior. http://purl.obolibrary.org/obo/GO_0035176 social behavior http://purl.obolibrary.org/obo/GO_0051703 intraspecies interaction between organisms Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group. http://purl.obolibrary.org/obo/GO_0035257 nuclear hormone receptor binding http://purl.obolibrary.org/obo/GO_0061629 RNA polymerase II-specific DNA-binding transcription factor binding Interacting selectively and non-covalently with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell. http://purl.obolibrary.org/obo/GO_0035264 multicellular organism growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of an entire multicellular organism, as opposed to cell growth. http://purl.obolibrary.org/obo/GO_0035456 response to interferon-beta http://purl.obolibrary.org/obo/GO_0034097 response to cytokine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon. http://purl.obolibrary.org/obo/GO_0035470 positive regulation of vascular wound healing http://purl.obolibrary.org/obo/GO_0061043 regulation of vascular wound healing Any process that increases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. http://purl.obolibrary.org/obo/GO_0035592 establishment of protein localization to extracellular region http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization The directed movement of a protein to a specific location within the extracellular region. http://purl.obolibrary.org/obo/GO_0035735 intraciliary transport involved in cilium assembly http://purl.obolibrary.org/obo/GO_0042073 intraciliary transport The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly. http://purl.obolibrary.org/obo/GO_0035821 modulation of process of other organism http://purl.obolibrary.org/obo/GO_0044419 interspecies interaction between organisms The process in which an organism effects a change in the structure or processes of another organism. http://purl.obolibrary.org/obo/GO_0035940 negative regulation of peptidase activity in other organism http://purl.obolibrary.org/obo/GO_0010466 negative regulation of peptidase activity Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism. http://purl.obolibrary.org/obo/GO_0036270 response to diuretic http://purl.obolibrary.org/obo/GO_0042493 response to drug Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diuretic stimulus. A diuretic is an agent that promotes the excretion of urine through its effects on kidney function. http://purl.obolibrary.org/obo/GO_0036271 response to methylphenidate http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylphenidate stimulus. http://purl.obolibrary.org/obo/GO_0036272 response to gemcitabine http://purl.obolibrary.org/obo/GO_0014070 response to organic cyclic compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gemcitabine stimulus. Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position, and is used as a drug in the treatment of various carcinomas. http://purl.obolibrary.org/obo/GO_0036273 response to statin http://purl.obolibrary.org/obo/GO_0042493 response to drug Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC:1.1.1.34/EC:1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties. http://purl.obolibrary.org/obo/GO_0036274 response to lapatinib http://purl.obolibrary.org/obo/GO_0014070 response to organic cyclic compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus. http://purl.obolibrary.org/obo/GO_0036275 response to 5-fluorouracil http://purl.obolibrary.org/obo/GO_0014070 response to organic cyclic compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluorouracil stimulus. http://purl.obolibrary.org/obo/GO_0036277 response to anticonvulsant http://purl.obolibrary.org/obo/GO_0042493 response to drug Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity. http://purl.obolibrary.org/obo/GO_0036287 response to iloperidone http://purl.obolibrary.org/obo/GO_0014070 response to organic cyclic compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iloperidone stimulus. http://purl.obolibrary.org/obo/GO_0036288 response to ximelagatran http://purl.obolibrary.org/obo/GO_0061476 response to anticoagulant Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ximelagatran stimulus. http://purl.obolibrary.org/obo/GO_0036385 nucleoid DNA packaging http://purl.obolibrary.org/obo/GO_0006323 DNA packaging Any process in which DNA and associated proteins are formed into a compact, orderly structure within a nucleoid. http://purl.obolibrary.org/obo/GO_0036386 bacterial nucleoid DNA packaging http://purl.obolibrary.org/obo/GO_0036385 nucleoid DNA packaging Compaction of DNA in a bacterial nucleoid into a compact structure. Often achieved by DNA supercoiling. http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of locomotion of a cell or organism. http://purl.obolibrary.org/obo/GO_0040013 negative regulation of locomotion http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism. http://purl.obolibrary.org/obo/GO_0040014 regulation of multicellular organism growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size. http://purl.obolibrary.org/obo/GO_0040015 negative regulation of multicellular organism growth http://purl.obolibrary.org/obo/GO_0040014 regulation of multicellular organism growth Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size. http://purl.obolibrary.org/obo/GO_0040016 embryonic cleavage http://purl.obolibrary.org/obo/GO_0051301 cell division The first few specialized divisions of an activated animal egg. http://purl.obolibrary.org/obo/GO_0040017 positive regulation of locomotion http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism. http://purl.obolibrary.org/obo/GO_0040018 positive regulation of multicellular organism growth http://purl.obolibrary.org/obo/GO_0048639 positive regulation of developmental growth Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size. http://purl.obolibrary.org/obo/GO_0040019 positive regulation of embryonic development http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of embryonic development. http://purl.obolibrary.org/obo/GO_0042073 intraciliary transport http://purl.obolibrary.org/obo/GO_0098840 protein transport along microtubule The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0042078 germ-line stem cell division http://purl.obolibrary.org/obo/GO_0017145 stem cell division The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes. http://purl.obolibrary.org/obo/GO_0042320 regulation of circadian sleep/wake cycle, REM sleep http://purl.obolibrary.org/obo/GO_0045187 regulation of circadian sleep/wake cycle, sleep Any process that modulates the frequency, rate or extent of rapid eye movement (REM) sleep. http://purl.obolibrary.org/obo/GO_0042321 negative regulation of circadian sleep/wake cycle, sleep http://purl.obolibrary.org/obo/GO_0045187 regulation of circadian sleep/wake cycle, sleep Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals. http://purl.obolibrary.org/obo/GO_0042322 negative regulation of circadian sleep/wake cycle, REM sleep http://purl.obolibrary.org/obo/GO_0042321 negative regulation of circadian sleep/wake cycle, sleep Any process that stops, prevents or reduces the duration or quality of rapid eye movement (REM) sleep. http://purl.obolibrary.org/obo/GO_0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep http://purl.obolibrary.org/obo/GO_0045188 regulation of circadian sleep/wake cycle, non-REM sleep Any process that stops, prevents or reduces the duration or quality of non-rapid eye movement (NREM) sleep. http://purl.obolibrary.org/obo/GO_0042331 phototaxis http://purl.obolibrary.org/obo/GO_0009453 energy taxis The directed movement of a motile cell or organism in response to light. http://purl.obolibrary.org/obo/GO_0042451 purine nucleoside biosynthetic process http://purl.obolibrary.org/obo/GO_0009163 nucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). http://purl.obolibrary.org/obo/GO_0042476 odontogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food. http://purl.obolibrary.org/obo/GO_0042481 regulation of odontogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth. http://purl.obolibrary.org/obo/GO_0042482 positive regulation of odontogenesis http://purl.obolibrary.org/obo/GO_0042481 regulation of odontogenesis Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth. http://purl.obolibrary.org/obo/GO_0042483 negative regulation of odontogenesis http://purl.obolibrary.org/obo/GO_0042481 regulation of odontogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth. http://purl.obolibrary.org/obo/GO_0042538 hyperosmotic salinity response http://purl.obolibrary.org/obo/GO_0009651 response to salt stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. http://purl.obolibrary.org/obo/GO_0042630 behavioral response to water deprivation http://purl.obolibrary.org/obo/GO_0007610 behavior Any process that results in a change in the behavior of an organism as a result of deprivation of water. http://purl.obolibrary.org/obo/GO_0042644 chloroplast nucleoid http://purl.obolibrary.org/obo/GO_0042646 plastid nucleoid The region of a chloroplast to which the DNA is confined. http://purl.obolibrary.org/obo/GO_0042647 proplastid nucleoid http://purl.obolibrary.org/obo/GO_0042646 plastid nucleoid The region of a proplastid to which the DNA is confined. http://purl.obolibrary.org/obo/GO_0042710 biofilm formation http://purl.obolibrary.org/obo/GO_0098630 aggregation of unicellular organisms A process in which planktonically growing microorganisms grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription. http://purl.obolibrary.org/obo/GO_0042747 circadian sleep/wake cycle, REM sleep http://purl.obolibrary.org/obo/GO_0022410 circadian sleep/wake cycle process A stage in the circadian sleep cycle during which dreams occur and the body undergoes marked changes including rapid eye movement, loss of reflexes, and increased pulse rate and brain activity. http://purl.obolibrary.org/obo/GO_0042748 circadian sleep/wake cycle, non-REM sleep http://purl.obolibrary.org/obo/GO_0022410 circadian sleep/wake cycle process All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions. http://purl.obolibrary.org/obo/GO_0042754 negative regulation of circadian rhythm http://purl.obolibrary.org/obo/GO_0042752 regulation of circadian rhythm Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior. http://purl.obolibrary.org/obo/GO_0043030 regulation of macrophage activation http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation Any process that modulates the frequency or rate of macrophage activation. http://purl.obolibrary.org/obo/GO_0043031 negative regulation of macrophage activation http://purl.obolibrary.org/obo/GO_0043030 regulation of macrophage activation Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation. http://purl.obolibrary.org/obo/GO_0043032 positive regulation of macrophage activation http://purl.obolibrary.org/obo/GO_0043030 regulation of macrophage activation Any process that stimulates, induces or increases the rate of macrophage activation. http://purl.obolibrary.org/obo/GO_0043045 DNA methylation involved in embryo development http://purl.obolibrary.org/obo/GO_1901538 changes to DNA methylation involved in embryo development The covalent transfer of a methyl group to C-5 of cytosine that contributes to the epigenetic regulation of embryonic gene expression. http://purl.obolibrary.org/obo/GO_0043046 DNA methylation involved in gamete generation http://purl.obolibrary.org/obo/GO_0022412 cellular process involved in reproduction in multicellular organism The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete. http://purl.obolibrary.org/obo/GO_0043209 myelin sheath http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system. http://purl.obolibrary.org/obo/GO_0043229 intracellular organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0043230 extracellular organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi. http://purl.obolibrary.org/obo/GO_0043278 response to morphine http://purl.obolibrary.org/obo/GO_0072347 response to anesthetic Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure. http://purl.obolibrary.org/obo/GO_0043388 positive regulation of DNA binding http://purl.obolibrary.org/obo/GO_0051101 regulation of DNA binding Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). http://purl.obolibrary.org/obo/GO_0043392 negative regulation of DNA binding http://purl.obolibrary.org/obo/GO_0051101 regulation of DNA binding Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). http://purl.obolibrary.org/obo/GO_0043590 bacterial nucleoid http://purl.obolibrary.org/obo/GO_0009295 nucleoid The region of a bacterial cell to which the DNA is confined. http://purl.obolibrary.org/obo/GO_0043620 regulation of DNA-templated transcription in response to stress http://purl.obolibrary.org/obo/GO_0033554 cellular response to stress Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_0043655 host extracellular space http://purl.obolibrary.org/obo/GO_0018995 host cellular component The space within a host but external to the plasma membrane of host cells, e.g. within host bloodstream. http://purl.obolibrary.org/obo/GO_0043903 regulation of symbiosis, encompassing mutualism through parasitism http://purl.obolibrary.org/obo/GO_0043900 regulation of multi-organism process Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association. http://purl.obolibrary.org/obo/GO_0043946 positive regulation of catalytic activity in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052203 modulation of catalytic activity in other organism involved in symbiotic interaction Any process in which an organism activates, maintains or increases the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0043948 induction by symbiont of host catalytic activity http://purl.obolibrary.org/obo/GO_0052148 modulation by symbiont of host catalytic activity Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0044010 single-species biofilm formation http://purl.obolibrary.org/obo/GO_0051703 intraspecies interaction between organisms A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription. http://purl.obolibrary.org/obo/GO_0044011 single-species biofilm formation on inanimate substrate http://purl.obolibrary.org/obo/GO_0090609 single-species submerged biofilm formation A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription. http://purl.obolibrary.org/obo/GO_0044030 regulation of DNA methylation http://purl.obolibrary.org/obo/GO_0051052 regulation of DNA metabolic process Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine. http://purl.obolibrary.org/obo/GO_0044062 regulation of excretion http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity. http://purl.obolibrary.org/obo/GO_0044063 modulation by symbiont of host nervous system process http://purl.obolibrary.org/obo/GO_0044003 modulation by symbiont of host process The alteration by a symbiont organism of the functioning of a host neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system. http://purl.obolibrary.org/obo/GO_0044069 modulation by symbiont of host anion transport http://purl.obolibrary.org/obo/GO_0044068 modulation by symbiont of host cellular process The process in which a symbiont organism modulates the anion transport, the directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, of its host organism. http://purl.obolibrary.org/obo/GO_0044071 modulation by symbiont of host cell cycle http://purl.obolibrary.org/obo/GO_0044068 modulation by symbiont of host cellular process The process in which a symbiont organism effects a change in its host's cell cycle through direct interactions with the host cell macromolecular machinery. http://purl.obolibrary.org/obo/GO_0044072 negative regulation by symbiont of host cell cycle http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process The process in which a symbiont organism stops, prevents or reduces the rate or extent of its host's progression through its cell cycle via direct interactions with the host cell macromolecular machinery. http://purl.obolibrary.org/obo/GO_0044090 positive regulation of vacuole organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. http://purl.obolibrary.org/obo/GO_0044110 growth involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0044419 interspecies interaction between organisms The increase in size or mass of an organism occurring when the organism is in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0044216 other organism cell http://purl.obolibrary.org/obo/GO_0044217 other organism part A cell of a secondary organism with which the first organism is interacting. http://purl.obolibrary.org/obo/GO_0044359 modulation of molecular function in other organism http://purl.obolibrary.org/obo/GO_0035821 modulation of process of other organism The process in which an organism effects a change in the function of proteins in a second organism. http://purl.obolibrary.org/obo/GO_0044362 negative regulation of molecular function in other organism http://purl.obolibrary.org/obo/GO_0044359 modulation of molecular function in other organism Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the function of proteins in a second organism. http://purl.obolibrary.org/obo/GO_0044531 modulation of programmed cell death in other organism http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death A process in which an organism modulates the frequency, rate or extent of programmed cell death in a second organism. http://purl.obolibrary.org/obo/GO_0044532 modulation of apoptotic process in other organism http://purl.obolibrary.org/obo/GO_0044531 modulation of programmed cell death in other organism A process in which an organism modulates the frequency, rate or extent of apoptosis in a second organism. http://purl.obolibrary.org/obo/GO_0044691 tooth eruption http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The tooth development process in which the teeth enter the mouth and become visible. http://purl.obolibrary.org/obo/GO_0044705 multi-organism reproductive behavior http://purl.obolibrary.org/obo/GO_0019098 reproductive behavior The specific behavior of an organism that is associated with reproduction involving another organism of the same or different species. http://purl.obolibrary.org/obo/GO_0044766 multi-organism transport http://purl.obolibrary.org/obo/GO_1902579 multi-organism localization The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving more than one organism. http://purl.obolibrary.org/obo/GO_0045121 membrane raft http://purl.obolibrary.org/obo/GO_0098857 membrane microdomain Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions. http://purl.obolibrary.org/obo/GO_0045144 meiotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0000819 sister chromatid segregation The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0045161 neuronal ion channel clustering http://purl.obolibrary.org/obo/GO_0061024 membrane organization The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation. http://purl.obolibrary.org/obo/GO_0045187 regulation of circadian sleep/wake cycle, sleep http://purl.obolibrary.org/obo/GO_0042749 regulation of circadian sleep/wake cycle Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals. http://purl.obolibrary.org/obo/GO_0045188 regulation of circadian sleep/wake cycle, non-REM sleep http://purl.obolibrary.org/obo/GO_0045187 regulation of circadian sleep/wake cycle, sleep Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep. http://purl.obolibrary.org/obo/GO_0045472 response to ether http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus. http://purl.obolibrary.org/obo/GO_0045475 locomotor rhythm http://purl.obolibrary.org/obo/GO_0048512 circadian behavior The rhythm of the locomotor activity of an organism during its 24 hour activity cycle. http://purl.obolibrary.org/obo/GO_0045647 negative regulation of erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0045646 regulation of erythrocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation. http://purl.obolibrary.org/obo/GO_0045648 positive regulation of erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0045646 regulation of erythrocyte differentiation Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation. http://purl.obolibrary.org/obo/GO_0045700 regulation of spermatid nuclear differentiation http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation. http://purl.obolibrary.org/obo/GO_0045701 negative regulation of spermatid nuclear differentiation http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation. http://purl.obolibrary.org/obo/GO_0045702 positive regulation of spermatid nuclear differentiation http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation. http://purl.obolibrary.org/obo/GO_0045724 positive regulation of cilium assembly http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of the formation of a cilium. http://purl.obolibrary.org/obo/GO_0045745 positive regulation of G protein-coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0008277 regulation of G protein-coupled receptor signaling pathway Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity. http://purl.obolibrary.org/obo/GO_0045766 positive regulation of angiogenesis http://purl.obolibrary.org/obo/GO_0045765 regulation of angiogenesis Any process that activates or increases angiogenesis. http://purl.obolibrary.org/obo/GO_0045769 negative regulation of asymmetric cell division http://purl.obolibrary.org/obo/GO_0009786 regulation of asymmetric cell division Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division. http://purl.obolibrary.org/obo/GO_0045770 positive regulation of asymmetric cell division http://purl.obolibrary.org/obo/GO_0009786 regulation of asymmetric cell division Any process that activates or increases the frequency, rate or extent of asymmetric cell division. http://purl.obolibrary.org/obo/GO_0045787 positive regulation of cell cycle http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the rate or extent of progression through the cell cycle. http://purl.obolibrary.org/obo/GO_0045937 positive regulation of phosphate metabolic process http://purl.obolibrary.org/obo/GO_0010562 positive regulation of phosphorus metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates. http://purl.obolibrary.org/obo/GO_0046128 purine ribonucleoside metabolic process http://purl.obolibrary.org/obo/GO_0009119 ribonucleoside metabolic process The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule. http://purl.obolibrary.org/obo/GO_0048018 receptor ligand activity http://purl.obolibrary.org/obo/GO_0030546 signaling receptor activator activity The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands). http://purl.obolibrary.org/obo/GO_0048102 autophagic cell death http://purl.obolibrary.org/obo/GO_0012501 programmed cell death A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells. http://purl.obolibrary.org/obo/GO_0048103 somatic stem cell division http://purl.obolibrary.org/obo/GO_0017145 stem cell division The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line. http://purl.obolibrary.org/obo/GO_0048199 vesicle targeting, to, from or within Golgi http://purl.obolibrary.org/obo/GO_0006903 vesicle targeting The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation. http://purl.obolibrary.org/obo/GO_0048639 positive regulation of developmental growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that activates, maintains or increases the rate of developmental growth. http://purl.obolibrary.org/obo/GO_0050802 circadian sleep/wake cycle, sleep http://purl.obolibrary.org/obo/GO_0030431 sleep The part of the circadian sleep/wake cycle where the organism is asleep. http://purl.obolibrary.org/obo/GO_0051098 regulation of binding http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. http://purl.obolibrary.org/obo/GO_0051101 regulation of DNA binding http://purl.obolibrary.org/obo/GO_0051098 regulation of binding Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). http://purl.obolibrary.org/obo/GO_0051222 positive regulation of protein transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051224 negative regulation of protein transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051328 meiotic interphase http://purl.obolibrary.org/obo/GO_0098762 meiotic cell cycle phase The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA. http://purl.obolibrary.org/obo/GO_0051338 regulation of transferase activity http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. http://purl.obolibrary.org/obo/GO_0051340 regulation of ligase activity http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6. http://purl.obolibrary.org/obo/GO_0051351 positive regulation of ligase activity http://purl.obolibrary.org/obo/GO_0051340 regulation of ligase activity Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. http://purl.obolibrary.org/obo/GO_0051352 negative regulation of ligase activity http://purl.obolibrary.org/obo/GO_0051340 regulation of ligase activity Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. http://purl.obolibrary.org/obo/GO_0051445 regulation of meiotic cell cycle http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the rate or extent of progression through the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051446 positive regulation of meiotic cell cycle http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051447 negative regulation of meiotic cell cycle http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051704 multi-organism process http://purl.obolibrary.org/obo/GO_0008150 biological_process A biological process which involves another organism of the same or different species. http://purl.obolibrary.org/obo/GO_0051817 modulation of process of other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0035821 modulation of process of other organism The process in which an organism effects a change in the structure or processes of a second organism, where the two organisms are in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0051818 disruption of cells of other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0051817 modulation of process of other organism involved in symbiotic interaction A process in which an organism has a negative effect on the functioning of the second organism's cells, where the two organisms are in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0051930 regulation of sensory perception of pain http://purl.obolibrary.org/obo/GO_0051931 regulation of sensory perception Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. http://purl.obolibrary.org/obo/GO_0052038 modulation by symbiont of host intracellular transport http://purl.obolibrary.org/obo/GO_0052230 modulation of intracellular transport in other organism involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052053 negative regulation by symbiont of host catalytic activity http://purl.obolibrary.org/obo/GO_0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052055 modulation by symbiont of host molecular function http://purl.obolibrary.org/obo/GO_0052205 modulation of molecular function in other organism involved in symbiotic interaction The process in which an organism effects a change in the function of a host protein via a direct interaction. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052056 negative regulation by symbiont of host molecular function http://purl.obolibrary.org/obo/GO_0052204 negative regulation of molecular function in other organism involved in symbiotic interaction Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of host proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052148 modulation by symbiont of host catalytic activity http://purl.obolibrary.org/obo/GO_0052203 modulation of catalytic activity in other organism involved in symbiotic interaction The process in which an organism effects a change in host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052203 modulation of catalytic activity in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052205 modulation of molecular function in other organism involved in symbiotic interaction The process in which an organism effects a change in enzyme activity in a second organism, where the two organisms are in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052204 negative regulation of molecular function in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052205 modulation of molecular function in other organism involved in symbiotic interaction Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of proteins in a second organism, where the two organisms are in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0055076 transition metal ion homeostasis http://purl.obolibrary.org/obo/GO_0055065 metal ion homeostasis Any process involved in the maintenance of an internal steady state of transition metal ions within an organism or cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. http://purl.obolibrary.org/obo/GO_0060271 cilium assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. http://purl.obolibrary.org/obo/GO_0060359 response to ammonium ion http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium ion stimulus. http://purl.obolibrary.org/obo/GO_0060467 negative regulation of fertilization http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). http://purl.obolibrary.org/obo/GO_0060548 negative regulation of cell death http://purl.obolibrary.org/obo/GO_0010941 regulation of cell death Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. http://purl.obolibrary.org/obo/GO_0061042 vascular wound healing http://purl.obolibrary.org/obo/GO_0060055 angiogenesis involved in wound healing Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. http://purl.obolibrary.org/obo/GO_0061043 regulation of vascular wound healing http://purl.obolibrary.org/obo/GO_0045765 regulation of angiogenesis Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. http://purl.obolibrary.org/obo/GO_0071383 cellular response to steroid hormone stimulus http://purl.obolibrary.org/obo/GO_0032870 cellular response to hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. http://purl.obolibrary.org/obo/GO_0071396 cellular response to lipid http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. http://purl.obolibrary.org/obo/GO_0071407 cellular response to organic cyclic compound http://purl.obolibrary.org/obo/GO_0014070 response to organic cyclic compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus. http://purl.obolibrary.org/obo/GO_0071467 cellular response to pH http://purl.obolibrary.org/obo/GO_0071214 cellular response to abiotic stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution. http://purl.obolibrary.org/obo/GO_0071692 protein localization to extracellular region http://purl.obolibrary.org/obo/GO_0008104 protein localization Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location. http://purl.obolibrary.org/obo/GO_0071867 response to monoamine http://purl.obolibrary.org/obo/GO_0010243 response to organonitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan. http://purl.obolibrary.org/obo/GO_0080154 regulation of fertilization http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). http://purl.obolibrary.org/obo/GO_0090316 positive regulation of intracellular protein transport http://purl.obolibrary.org/obo/GO_1903829 positive regulation of cellular protein localization Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells. http://purl.obolibrary.org/obo/GO_0090317 negative regulation of intracellular protein transport http://purl.obolibrary.org/obo/GO_1903828 negative regulation of cellular protein localization Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells. http://purl.obolibrary.org/obo/GO_0090330 regulation of platelet aggregation http://purl.obolibrary.org/obo/GO_0010543 regulation of platelet activation Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules. http://purl.obolibrary.org/obo/GO_0090331 negative regulation of platelet aggregation http://purl.obolibrary.org/obo/GO_0010544 negative regulation of platelet activation Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules. http://purl.obolibrary.org/obo/GO_0090605 submerged biofilm formation http://purl.obolibrary.org/obo/GO_0042710 biofilm formation A process in which planktonically growing microorganisms aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription. http://purl.obolibrary.org/obo/GO_0090609 single-species submerged biofilm formation http://purl.obolibrary.org/obo/GO_0090605 submerged biofilm formation A process in which planktonically growing microorganisms of the same species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription. http://purl.obolibrary.org/obo/GO_0098794 postsynapse http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity The part of a synapse that is part of the post-synaptic cell. http://purl.obolibrary.org/obo/GO_0098840 protein transport along microtubule http://purl.obolibrary.org/obo/GO_0099118 microtubule-based protein transport The directed movement of a protein along a microtubule, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0098857 membrane microdomain http://purl.obolibrary.org/obo/GO_0098589 membrane region A membrane region with a lipid composition that is distinct from that of the membrane regions that surround it. http://purl.obolibrary.org/obo/GO_1900116 extracellular negative regulation of signal transduction http://purl.obolibrary.org/obo/GO_1900115 extracellular regulation of signal transduction Any negative regulation of signal transduction that takes place in extracellular region. http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of vasculature development. http://purl.obolibrary.org/obo/GO_1901538 changes to DNA methylation involved in embryo development http://purl.obolibrary.org/obo/GO_0044728 DNA methylation or demethylation The addition or removal of methyl groups to DNA that contributes to the epigenetic regulation of embryonic gene expression. http://purl.obolibrary.org/obo/GO_1901731 positive regulation of platelet aggregation http://purl.obolibrary.org/obo/GO_0010572 positive regulation of platelet activation Any process that activates or increases the frequency, rate or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules. http://purl.obolibrary.org/obo/GO_1902017 regulation of cilium assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that modulates the frequency, rate or extent of cilium assembly. http://purl.obolibrary.org/obo/GO_1902579 multi-organism localization http://purl.obolibrary.org/obo/GO_0051704 multi-organism process A localization which involves another organism. http://purl.obolibrary.org/obo/GO_1903665 negative regulation of asexual reproduction http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents or reduces the frequency, rate or extent of asexual reproduction. http://purl.obolibrary.org/obo/GO_1903666 positive regulation of asexual reproduction http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates or increases the frequency, rate or extent of asexual reproduction. http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of hemopoiesis. http://purl.obolibrary.org/obo/GO_1903707 negative regulation of hemopoiesis http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis. http://purl.obolibrary.org/obo/GO_1903708 positive regulation of hemopoiesis http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis Any process that activates or increases the frequency, rate or extent of hemopoiesis. http://purl.obolibrary.org/obo/GO_1903998 regulation of eating behavior http://purl.obolibrary.org/obo/GO_0060259 regulation of feeding behavior Any process that modulates the frequency, rate or extent of eating behavior. http://purl.obolibrary.org/obo/GO_1904018 positive regulation of vasculature development http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development Any process that activates or increases the frequency, rate or extent of vasculature development. http://purl.obolibrary.org/obo/GO_1990215 negative regulation by symbiont of host intracellular transport http://purl.obolibrary.org/obo/GO_0052038 modulation by symbiont of host intracellular transport Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of intracellular transport in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_2001021 negative regulation of response to DNA damage stimulus http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus Any process that stops, prevents or reduces the frequency, rate or extent of response to DNA damage stimulus. http://purl.obolibrary.org/obo/GO_2001022 positive regulation of response to DNA damage stimulus http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of response to DNA damage stimulus. http://purl.obolibrary.org/obo/GO_0090139 mitochondrial DNA packaging http://purl.obolibrary.org/obo/GO_0036385 nucleoid DNA packaging Any process in which mitochondrial DNA and associated proteins are formed into a compact, orderly structure. http://purl.obolibrary.org/obo/GO_0090169 regulation of spindle assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart. http://purl.obolibrary.org/obo/GO_0090227 regulation of red or far-red light signaling pathway http://purl.obolibrary.org/obo/GO_2000030 regulation of response to red or far red light Any process that modulates the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. http://purl.obolibrary.org/obo/GO_0090228 positive regulation of red or far-red light signaling pathway http://purl.obolibrary.org/obo/GO_0090227 regulation of red or far-red light signaling pathway Any process that increases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. http://purl.obolibrary.org/obo/GO_0090229 negative regulation of red or far-red light signaling pathway http://purl.obolibrary.org/obo/GO_0090227 regulation of red or far-red light signaling pathway Any process that decreases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. http://purl.obolibrary.org/obo/GO_0090283 regulation of protein glycosylation in Golgi http://purl.obolibrary.org/obo/GO_0060049 regulation of protein glycosylation Any process that modulates the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0090284 positive regulation of protein glycosylation in Golgi http://purl.obolibrary.org/obo/GO_0060050 positive regulation of protein glycosylation Any process that increases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0090285 negative regulation of protein glycosylation in Golgi http://purl.obolibrary.org/obo/GO_0060051 negative regulation of protein glycosylation Any process that decreases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0090325 regulation of locomotion involved in locomotory behavior http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. http://purl.obolibrary.org/obo/GO_0090326 positive regulation of locomotion involved in locomotory behavior http://purl.obolibrary.org/obo/GO_0048520 positive regulation of behavior Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. http://purl.obolibrary.org/obo/GO_0090327 negative regulation of locomotion involved in locomotory behavior http://purl.obolibrary.org/obo/GO_0090325 regulation of locomotion involved in locomotory behavior Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. http://purl.obolibrary.org/obo/GO_0090328 regulation of olfactory learning http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior Any process that modulates the rate, frequency, or extent of olfactory learning. Olfactory learning is any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue. http://purl.obolibrary.org/obo/GO_0097270 dishabituation http://purl.obolibrary.org/obo/GO_0046958 nonassociative learning The temporary recovery of response to a stimulus when a novel stimulus is added. http://purl.obolibrary.org/obo/GO_0097327 response to antineoplastic agent http://purl.obolibrary.org/obo/GO_0042493 response to drug Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antineoplastic agent stimulus. An antineoplastic agent is a substance that inhibits or prevents the proliferation of neoplasms. http://purl.obolibrary.org/obo/GO_0097328 response to carboplatin http://purl.obolibrary.org/obo/GO_0097327 response to antineoplastic agent Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carboplatin stimulus. http://purl.obolibrary.org/obo/GO_0097329 response to antimetabolite http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimetabolite stimulus. An antimetabolite is a substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization. http://purl.obolibrary.org/obo/GO_0097330 response to 5-fluoro-2'-deoxyuridine http://purl.obolibrary.org/obo/GO_0014070 response to organic cyclic compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluoro-2'-deoxyuridine stimulus. 5-fluoro-2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; it is used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract. http://purl.obolibrary.org/obo/GO_0097331 response to cytarabine http://purl.obolibrary.org/obo/GO_0014070 response to organic cyclic compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytarabine stimulus. http://purl.obolibrary.org/obo/GO_0097332 response to antipsychotic drug http://purl.obolibrary.org/obo/GO_0042493 response to drug Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. http://purl.obolibrary.org/obo/GO_0097333 response to olanzapine http://purl.obolibrary.org/obo/GO_0014070 response to organic cyclic compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an olanzapine stimulus. http://purl.obolibrary.org/obo/GO_0097334 response to perphenazine http://purl.obolibrary.org/obo/GO_0097305 response to alcohol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a perphenazine stimulus. Perphenazine is a phenothiazine derivative having a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position. http://purl.obolibrary.org/obo/GO_0097335 response to quetiapine http://purl.obolibrary.org/obo/GO_0014070 response to organic cyclic compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quetiapine stimulus. http://purl.obolibrary.org/obo/GO_0097336 response to risperidone http://purl.obolibrary.org/obo/GO_0014070 response to organic cyclic compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a risperidone stimulus. http://purl.obolibrary.org/obo/GO_0097337 response to ziprasidone http://purl.obolibrary.org/obo/GO_0014070 response to organic cyclic compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ziprasidone stimulus. Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms. http://purl.obolibrary.org/obo/GO_0097338 response to clozapine http://purl.obolibrary.org/obo/GO_0014070 response to organic cyclic compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus. http://purl.obolibrary.org/obo/GO_0097366 response to bronchodilator http://purl.obolibrary.org/obo/GO_0042493 response to drug Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes. http://purl.obolibrary.org/obo/GO_0097711 ciliary basal body-plasma membrane docking http://purl.obolibrary.org/obo/GO_0140056 organelle localization by membrane tethering The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane. http://purl.obolibrary.org/obo/GO_0098631 cell adhesion mediator activity http://purl.obolibrary.org/obo/GO_0005488 binding The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell. http://purl.obolibrary.org/obo/GO_0098632 cell-cell adhesion mediator activity http://purl.obolibrary.org/obo/GO_0098631 cell adhesion mediator activity The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell. http://purl.obolibrary.org/obo/GO_0099091 postsynaptic specialization, intracellular component http://purl.obolibrary.org/obo/GO_0043228 non-membrane-bounded organelle A network of proteins adjacent to the postsynaptic membrane. Its major components include the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. http://purl.obolibrary.org/obo/GO_0099092 postsynaptic density, intracellular component http://purl.obolibrary.org/obo/GO_0099091 postsynaptic specialization, intracellular component A network of proteins adjacent to the postsynaptic membrane forming an electron dense disc. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. http://purl.obolibrary.org/obo/GO_0099118 microtubule-based protein transport http://purl.obolibrary.org/obo/GO_0099111 microtubule-based transport A microtubule-based process that results in the transport of proteins. http://purl.obolibrary.org/obo/GO_0099522 region of cytosol http://purl.obolibrary.org/obo/GO_0005829 cytosol Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol http://purl.obolibrary.org/obo/GO_0099524 postsynaptic cytosol http://purl.obolibrary.org/obo/GO_0099522 region of cytosol The region of the cytosol consisting of all cytosol that is part of the postsynapse. http://purl.obolibrary.org/obo/GO_0099536 synaptic signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Cell-cell signaling to, from or within a synapse. http://purl.obolibrary.org/obo/GO_0099571 postsynaptic cytoskeleton http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton The portion of the cytoskeleton contained within the postsynapse. http://purl.obolibrary.org/obo/GO_1900115 extracellular regulation of signal transduction http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction Any regulation of signal transduction that takes place in the extracellular region. http://purl.obolibrary.org/obo/GO_1900117 regulation of execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_1900118 negative regulation of execution phase of apoptosis http://purl.obolibrary.org/obo/GO_1900117 regulation of execution phase of apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_1900119 positive regulation of execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_1900160 plastid DNA packaging http://purl.obolibrary.org/obo/GO_0036385 nucleoid DNA packaging Any process in which plastidial DNA and associated proteins are formed into a compact, orderly structure. http://purl.obolibrary.org/obo/GO_1900190 regulation of single-species biofilm formation http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of single-species biofilm formation. http://purl.obolibrary.org/obo/GO_1900191 negative regulation of single-species biofilm formation http://purl.obolibrary.org/obo/GO_1900190 regulation of single-species biofilm formation Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation. http://purl.obolibrary.org/obo/GO_1900192 positive regulation of single-species biofilm formation http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of single-species biofilm formation. http://purl.obolibrary.org/obo/GO_1900231 regulation of single-species biofilm formation on inanimate substrate http://purl.obolibrary.org/obo/GO_1900190 regulation of single-species biofilm formation Any process that modulates the frequency, rate or extent of single-species biofilm formation on inanimate substrate. http://purl.obolibrary.org/obo/GO_1900232 negative regulation of single-species biofilm formation on inanimate substrate http://purl.obolibrary.org/obo/GO_1900231 regulation of single-species biofilm formation on inanimate substrate Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation on inanimate substrate. http://purl.obolibrary.org/obo/GO_1900233 positive regulation of single-species biofilm formation on inanimate substrate http://purl.obolibrary.org/obo/GO_1900231 regulation of single-species biofilm formation on inanimate substrate Any process that activates or increases the frequency, rate or extent of single-species biofilm formation on inanimate substrate. http://purl.obolibrary.org/obo/GO_1900368 regulation of RNA interference http://purl.obolibrary.org/obo/GO_0060147 regulation of posttranscriptional gene silencing Any process that modulates the frequency, rate or extent of RNA interference. http://purl.obolibrary.org/obo/GO_1900369 negative regulation of RNA interference http://purl.obolibrary.org/obo/GO_0060967 negative regulation of gene silencing by RNA Any process that stops, prevents or reduces the frequency, rate or extent of RNA interference. http://purl.obolibrary.org/obo/GO_1900370 positive regulation of RNA interference http://purl.obolibrary.org/obo/GO_0060148 positive regulation of posttranscriptional gene silencing Any process that activates or increases the frequency, rate or extent of RNA interference. http://purl.obolibrary.org/obo/GO_1901000 regulation of response to salt stress http://purl.obolibrary.org/obo/GO_0047484 regulation of response to osmotic stress Any process that modulates the frequency, rate or extent of response to salt stress. http://purl.obolibrary.org/obo/GO_1901001 negative regulation of response to salt stress http://purl.obolibrary.org/obo/GO_1901000 regulation of response to salt stress Any process that stops, prevents or reduces the frequency, rate or extent of response to salt stress. http://purl.obolibrary.org/obo/GO_1901002 positive regulation of response to salt stress http://purl.obolibrary.org/obo/GO_1901000 regulation of response to salt stress Any process that activates or increases the frequency, rate or extent of response to salt stress. http://purl.obolibrary.org/obo/GO_1901148 gene expression involved in extracellular matrix organization http://purl.obolibrary.org/obo/GO_0010467 gene expression Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/GO_1901401 regulation of tetrapyrrole metabolic process http://purl.obolibrary.org/obo/GO_0051171 regulation of nitrogen compound metabolic process Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process. http://purl.obolibrary.org/obo/GO_1901858 regulation of mitochondrial DNA metabolic process http://purl.obolibrary.org/obo/GO_0010821 regulation of mitochondrion organization Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process. http://purl.obolibrary.org/obo/GO_1901859 negative regulation of mitochondrial DNA metabolic process http://purl.obolibrary.org/obo/GO_0010823 negative regulation of mitochondrion organization Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process. http://purl.obolibrary.org/obo/GO_1901860 positive regulation of mitochondrial DNA metabolic process http://purl.obolibrary.org/obo/GO_0010822 positive regulation of mitochondrion organization Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process. http://purl.obolibrary.org/obo/GO_1903829 positive regulation of cellular protein localization http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. http://purl.obolibrary.org/obo/GO_2001233 regulation of apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_2001234 negative regulation of apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_2001233 regulation of apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_2001235 positive regulation of apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_1901317 regulation of flagellated sperm motility http://purl.obolibrary.org/obo/GO_1902019 regulation of cilium-dependent cell motility Any process that modulates the frequency, rate or extent of flagellated sperm motility. http://purl.obolibrary.org/obo/GO_1901318 negative regulation of flagellated sperm motility http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility. http://purl.obolibrary.org/obo/GO_1901402 negative regulation of tetrapyrrole metabolic process http://purl.obolibrary.org/obo/GO_0051172 negative regulation of nitrogen compound metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process. http://purl.obolibrary.org/obo/GO_1901403 positive regulation of tetrapyrrole metabolic process http://purl.obolibrary.org/obo/GO_1901401 regulation of tetrapyrrole metabolic process Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process. http://purl.obolibrary.org/obo/GO_1901554 response to paracetamol http://purl.obolibrary.org/obo/GO_0042493 response to drug Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paracetamol stimulus. http://purl.obolibrary.org/obo/GO_1901555 response to paclitaxel http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paclitaxel stimulus. http://purl.obolibrary.org/obo/GO_1901556 response to candesartan http://purl.obolibrary.org/obo/GO_0042493 response to drug Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a candesartan stimulus. http://purl.obolibrary.org/obo/GO_1901557 response to fenofibrate http://purl.obolibrary.org/obo/GO_0042493 response to drug Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fenofibrate stimulus. http://purl.obolibrary.org/obo/GO_1901558 response to metformin http://purl.obolibrary.org/obo/GO_0042493 response to drug Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metformin stimulus. http://purl.obolibrary.org/obo/GO_1901559 response to ribavirin http://purl.obolibrary.org/obo/GO_0061479 response to reverse transcriptase inhibitor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ribavirin stimulus. http://purl.obolibrary.org/obo/GO_1901673 regulation of mitotic spindle assembly http://purl.obolibrary.org/obo/GO_0090169 regulation of spindle assembly Any process that modulates the frequency, rate or extent of mitotic spindle assembly. http://purl.obolibrary.org/obo/GO_1901738 regulation of vitamin A metabolic process http://purl.obolibrary.org/obo/GO_0030656 regulation of vitamin metabolic process Any process that modulates the frequency, rate or extent of vitamin A metabolic process. http://purl.obolibrary.org/obo/GO_1901905 response to tamsulosin http://purl.obolibrary.org/obo/GO_0014070 response to organic cyclic compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tamsulosin stimulus. http://purl.obolibrary.org/obo/GO_1902018 negative regulation of cilium assembly http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly. http://purl.obolibrary.org/obo/GO_1902020 negative regulation of cilium-dependent cell motility http://purl.obolibrary.org/obo/GO_1902019 regulation of cilium-dependent cell motility Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility. http://purl.obolibrary.org/obo/GO_1902064 regulation of transcription from RNA polymerase II promoter involved in spermatogenesis http://purl.obolibrary.org/obo/GO_0022414 reproductive process Any regulation of transcription from RNA polymerase II promoter that is involved in spermatogenesis. http://purl.obolibrary.org/obo/GO_1902074 response to salt http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus. http://purl.obolibrary.org/obo/GO_1902119 regulation of meiotic spindle elongation http://purl.obolibrary.org/obo/GO_0040020 regulation of meiotic nuclear division Any process that modulates the frequency, rate or extent of meiotic spindle elongation. http://purl.obolibrary.org/obo/GO_1902120 negative regulation of meiotic spindle elongation http://purl.obolibrary.org/obo/GO_0051494 negative regulation of cytoskeleton organization Any process that stops, prevents or reduces the frequency, rate or extent of meiotic spindle elongation. http://purl.obolibrary.org/obo/GO_1902262 apoptotic process involved in blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0060561 apoptotic process involved in morphogenesis Any apoptotic process that is involved in blood vessel morphogenesis. http://purl.obolibrary.org/obo/GO_1902340 negative regulation of chromosome condensation http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation. http://purl.obolibrary.org/obo/GO_1902518 response to cyclophosphamide http://purl.obolibrary.org/obo/GO_0010243 response to organonitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclophosphamide stimulus. http://purl.obolibrary.org/obo/GO_1902519 response to docetaxel trihydrate http://purl.obolibrary.org/obo/GO_0097305 response to alcohol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a docetaxel trihydrate stimulus. http://purl.obolibrary.org/obo/GO_1902520 response to doxorubicin http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus. http://purl.obolibrary.org/obo/GO_1902521 response to etoposide http://purl.obolibrary.org/obo/GO_0014070 response to organic cyclic compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an etoposide stimulus. http://purl.obolibrary.org/obo/GO_1902522 response to 4'-epidoxorubicin http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4'-epidoxorubicin stimulus. http://purl.obolibrary.org/obo/GO_1902581 multi-organism cellular localization http://purl.obolibrary.org/obo/GO_1902579 multi-organism localization A cellular localization which involves another organism. http://purl.obolibrary.org/obo/GO_1902584 positive regulation of response to water deprivation http://purl.obolibrary.org/obo/GO_2000070 regulation of response to water deprivation Any process that activates or increases the frequency, rate or extent of response to water deprivation. http://purl.obolibrary.org/obo/GO_1902845 negative regulation of mitotic spindle elongation http://purl.obolibrary.org/obo/GO_0051494 negative regulation of cytoskeleton organization Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle elongation. http://purl.obolibrary.org/obo/GO_1902846 positive regulation of mitotic spindle elongation http://purl.obolibrary.org/obo/GO_0062033 positive regulation of mitotic sister chromatid segregation Any process that activates or increases the frequency, rate or extent of mitotic spindle elongation. http://purl.obolibrary.org/obo/GO_1902902 negative regulation of autophagosome assembly http://purl.obolibrary.org/obo/GO_1902116 negative regulation of organelle assembly Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly. http://purl.obolibrary.org/obo/GO_1903109 positive regulation of mitochondrial transcription http://purl.obolibrary.org/obo/GO_1903108 regulation of mitochondrial transcription Any process that activates or increases the frequency, rate or extent of transcription occuring in the mitochondrion. http://purl.obolibrary.org/obo/GO_1903379 regulation of mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation Any process that modulates the frequency, rate or extent of mitotic chromosome condensation. http://purl.obolibrary.org/obo/GO_1903380 positive regulation of mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_0062033 positive regulation of mitotic sister chromatid segregation Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation. http://purl.obolibrary.org/obo/GO_1903453 RNA interference involved in olfactory learning http://purl.obolibrary.org/obo/GO_0016246 RNA interference Any RNA interference that is involved in olfactory learning. http://purl.obolibrary.org/obo/GO_1903491 response to simvastatin http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a simvastatin stimulus. Simvastatin is a statin used as a cholesterol-lowering and anti-cardiovascular disease drug. http://purl.obolibrary.org/obo/GO_1903492 response to acetylsalicylate http://purl.obolibrary.org/obo/GO_0061478 response to platelet aggregation inhibitor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aspirin (acetylsalicylate) stimulus. Aspirin is a non-steroidal anti-inflammatory drug with moA cyclooxygenase inhibitor activity. http://purl.obolibrary.org/obo/GO_1903493 response to clopidogrel http://purl.obolibrary.org/obo/GO_0061478 response to platelet aggregation inhibitor Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clopidogrel stimulus. Clopidogrel is a is an oral, thienopyridine-class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. http://purl.obolibrary.org/obo/GO_1903551 regulation of extracellular exosome assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly. http://purl.obolibrary.org/obo/GO_1903552 negative regulation of extracellular exosome assembly http://purl.obolibrary.org/obo/GO_1902116 negative regulation of organelle assembly Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly. http://purl.obolibrary.org/obo/GO_1903553 positive regulation of extracellular exosome assembly http://purl.obolibrary.org/obo/GO_1902117 positive regulation of organelle assembly Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly. http://purl.obolibrary.org/obo/GO_1903564 regulation of protein localization to cilium http://purl.obolibrary.org/obo/GO_1903827 regulation of cellular protein localization Any process that modulates the frequency, rate or extent of protein localization to cilium. http://purl.obolibrary.org/obo/GO_1903565 negative regulation of protein localization to cilium http://purl.obolibrary.org/obo/GO_1903828 negative regulation of cellular protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium. http://purl.obolibrary.org/obo/GO_1903566 positive regulation of protein localization to cilium http://purl.obolibrary.org/obo/GO_1903564 regulation of protein localization to cilium Any process that activates or increases the frequency, rate or extent of protein localization to cilium. http://purl.obolibrary.org/obo/GO_1903649 regulation of cytoplasmic transport http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of cytoplasmic transport. http://purl.obolibrary.org/obo/GO_1903650 negative regulation of cytoplasmic transport http://purl.obolibrary.org/obo/GO_1903649 regulation of cytoplasmic transport Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport. http://purl.obolibrary.org/obo/GO_1903651 positive regulation of cytoplasmic transport http://purl.obolibrary.org/obo/GO_1903649 regulation of cytoplasmic transport Any process that activates or increases the frequency, rate or extent of cytoplasmic transport. http://purl.obolibrary.org/obo/GO_1903653 modulation by symbiont of host cell motility http://purl.obolibrary.org/obo/GO_2000145 regulation of cell motility Modulation of host cell motility by a symbiont of that host. http://purl.obolibrary.org/obo/GO_1904631 response to glucoside http://purl.obolibrary.org/obo/GO_1903416 response to glycoside Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus. http://purl.obolibrary.org/obo/GO_1905821 positive regulation of chromosome condensation http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation Any process that activates or increases the frequency, rate or extent of chromosome condensation. http://purl.obolibrary.org/obo/GO_2000785 regulation of autophagosome assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that modulates the frequency, rate or extent of autophagosome assembly. http://purl.obolibrary.org/obo/GO_1905642 negative regulation of DNA methylation http://purl.obolibrary.org/obo/GO_0044030 regulation of DNA methylation Any process that stops, prevents or reduces the frequency, rate or extent of DNA methylation. http://purl.obolibrary.org/obo/GO_1905643 positive regulation of DNA methylation http://purl.obolibrary.org/obo/GO_0044030 regulation of DNA methylation Any process that activates or increases the frequency, rate or extent of DNA methylation. http://purl.obolibrary.org/obo/GO_1905831 negative regulation of spindle assembly http://purl.obolibrary.org/obo/GO_1902116 negative regulation of organelle assembly Any process that stops, prevents or reduces the frequency, rate or extent of spindle assembly. http://purl.obolibrary.org/obo/GO_1905832 positive regulation of spindle assembly http://purl.obolibrary.org/obo/GO_1902117 positive regulation of organelle assembly Any process that activates or increases the frequency, rate or extent of spindle assembly. http://purl.obolibrary.org/obo/GO_1905843 regulation of cellular response to gamma radiation http://purl.obolibrary.org/obo/GO_2001228 regulation of response to gamma radiation Any process that modulates the frequency, rate or extent of cellular response to gamma radiation. http://purl.obolibrary.org/obo/GO_1905844 negative regulation of cellular response to gamma radiation http://purl.obolibrary.org/obo/GO_2001229 negative regulation of response to gamma radiation Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to gamma radiation. http://purl.obolibrary.org/obo/GO_1905845 positive regulation of cellular response to gamma radiation http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cellular response to gamma radiation. http://purl.obolibrary.org/obo/GO_1905864 regulation of Atg1/ULK1 kinase complex assembly http://purl.obolibrary.org/obo/GO_0043254 regulation of protein-containing complex assembly Any process that modulates the frequency, rate or extent of Atg1/ULK1 kinase complex assembly. http://purl.obolibrary.org/obo/GO_1905865 negative regulation of Atg1/ULK1 kinase complex assembly http://purl.obolibrary.org/obo/GO_1905864 regulation of Atg1/ULK1 kinase complex assembly Any process that stops, prevents or reduces the frequency, rate or extent of Atg1/ULK1 kinase complex assembly. http://purl.obolibrary.org/obo/GO_1905866 positive regulation of Atg1/ULK1 kinase complex assembly http://purl.obolibrary.org/obo/GO_1905864 regulation of Atg1/ULK1 kinase complex assembly Any process that activates or increases the frequency, rate or extent of Atg1/ULK1 kinase complex assembly. http://purl.obolibrary.org/obo/GO_1990054 response to temozolomide http://purl.obolibrary.org/obo/GO_0014070 response to organic cyclic compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temozolomide stimulus. http://purl.obolibrary.org/obo/GO_1990110 callus formation http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process by which a callus is formed at a wound site. A plant callus is a portion of plant tissue that consists of mass of undifferentiated plant cells. It consists primarily of parenchyma cells but possibly contains other cell types as the callus begins to differentiate. http://purl.obolibrary.org/obo/GO_1990603 dark adaptation http://purl.obolibrary.org/obo/GO_0071485 cellular response to absence of light The process by which the rods of the retina gradually become fully responsive to dim light when no longer exposed to bright light. http://purl.obolibrary.org/obo/GO_1990708 conditioned place preference http://purl.obolibrary.org/obo/GO_0008306 associative learning The associative learning process by which an animal learns and remembers an association between a neutral, unchanging environment and a putatively rewarding, internal state produced by a xenobiotic or drug. http://purl.obolibrary.org/obo/GO_2000155 positive regulation of cilium-dependent cell motility http://purl.obolibrary.org/obo/GO_1902019 regulation of cilium-dependent cell motility Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility. http://purl.obolibrary.org/obo/GO_2000683 regulation of cellular response to X-ray http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cellular response to X-ray. http://purl.obolibrary.org/obo/GO_2000684 negative regulation of cellular response to X-ray http://purl.obolibrary.org/obo/GO_2000683 regulation of cellular response to X-ray Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to X-ray. http://purl.obolibrary.org/obo/GO_2000685 positive regulation of cellular response to X-ray http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cellular response to X-ray. http://purl.obolibrary.org/obo/GO_2000786 positive regulation of autophagosome assembly http://purl.obolibrary.org/obo/GO_1902117 positive regulation of organelle assembly Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly. http://purl.obolibrary.org/obo/GO_2001023 regulation of response to drug http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of response to drug. http://purl.obolibrary.org/obo/GO_2001024 negative regulation of response to drug http://purl.obolibrary.org/obo/GO_2001023 regulation of response to drug Any process that stops, prevents or reduces the frequency, rate or extent of response to drug. http://purl.obolibrary.org/obo/GO_2001025 positive regulation of response to drug http://purl.obolibrary.org/obo/GO_2001023 regulation of response to drug Any process that activates or increases the frequency, rate or extent of response to drug. http://purl.obolibrary.org/obo/GO_2001169 regulation of ATP biosynthetic process http://purl.obolibrary.org/obo/GO_1900371 regulation of purine nucleotide biosynthetic process Any process that modulates the frequency, rate or extent of ATP biosynthetic process. http://purl.obolibrary.org/obo/GO_2001170 negative regulation of ATP biosynthetic process http://purl.obolibrary.org/obo/GO_2001169 regulation of ATP biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process. http://purl.obolibrary.org/obo/GO_2001171 positive regulation of ATP biosynthetic process http://purl.obolibrary.org/obo/GO_2001169 regulation of ATP biosynthetic process Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process. http://purl.obolibrary.org/obo/GO_2001228 regulation of response to gamma radiation http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of response to gamma radiation. http://purl.obolibrary.org/obo/GO_2001229 negative regulation of response to gamma radiation http://purl.obolibrary.org/obo/GO_2001228 regulation of response to gamma radiation Any process that stops, prevents or reduces the frequency, rate or extent of response to gamma radiation. http://purl.obolibrary.org/obo/GO_2001230 positive regulation of response to gamma radiation http://purl.obolibrary.org/obo/GO_2001228 regulation of response to gamma radiation Any process that activates or increases the frequency, rate or extent of response to gamma radiation. http://purl.obolibrary.org/obo/RO_0002577 system http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity consisting of multiple components that are causally integrated. http://purl.obolibrary.org/obo/GO_0140039 cell-cell adhesion in response to extracellular stimulus http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion The attachment of one cell to another cell via adhesion molecules as a result of an extracellular stimulus. http://purl.obolibrary.org/obo/PATO_0040025 lesioned http://purl.obolibrary.org/obo/PATO_0000141 structure A structural quality which is held by a bearer where a localized pathological or traumatic structural change, damage, deformity, or discontinuity of tissue, organ, or body part is present. http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity http://purl.obolibrary.org/obo/GO_0005575 cellular_component A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. http://purl.obolibrary.org/obo/GO_0062149 detection of stimulus involved in sensory perception of pain http://purl.obolibrary.org/obo/GO_0050906 detection of stimulus involved in sensory perception The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0008219 cell death http://purl.obolibrary.org/obo/GO_0009987 cellular process Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538). http://purl.obolibrary.org/obo/GO_0008233 peptidase activity http://purl.obolibrary.org/obo/GO_0140096 catalytic activity, acting on a protein Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid. http://purl.obolibrary.org/obo/GO_0008277 regulation of G protein-coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway. http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of cell proliferation. http://purl.obolibrary.org/obo/GO_0008355 olfactory learning http://purl.obolibrary.org/obo/GO_0042048 olfactory behavior Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue. http://purl.obolibrary.org/obo/GO_0008517 folic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0090482 vitamin transmembrane transporter activity Enables the transfer of folic acid (pteroylglutamic acid) from one side of a membrane to the other. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines. http://purl.obolibrary.org/obo/GO_0008542 visual learning http://purl.obolibrary.org/obo/GO_0008306 associative learning Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue. http://purl.obolibrary.org/obo/GO_0009056 catabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. http://purl.obolibrary.org/obo/GO_0009118 regulation of nucleoside metabolic process http://purl.obolibrary.org/obo/GO_0062012 regulation of small molecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides. http://purl.obolibrary.org/obo/GO_0009119 ribonucleoside metabolic process http://purl.obolibrary.org/obo/GO_0009116 nucleoside metabolic process The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule. http://purl.obolibrary.org/obo/GO_0009123 nucleoside monophosphate metabolic process http://purl.obolibrary.org/obo/GO_0006753 nucleoside phosphate metabolic process The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009124 nucleoside monophosphate biosynthetic process http://purl.obolibrary.org/obo/GO_1901293 nucleoside phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009126 purine nucleoside monophosphate metabolic process http://purl.obolibrary.org/obo/GO_0009123 nucleoside monophosphate metabolic process The chemical reactions and pathways involving purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009127 purine nucleoside monophosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0009126 purine nucleoside monophosphate metabolic process The chemical reactions and pathways resulting in the formation of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009141 nucleoside triphosphate metabolic process http://purl.obolibrary.org/obo/GO_0006753 nucleoside phosphate metabolic process The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009142 nucleoside triphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_1901293 nucleoside phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009144 purine nucleoside triphosphate metabolic process http://purl.obolibrary.org/obo/GO_0009141 nucleoside triphosphate metabolic process The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009145 purine nucleoside triphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0009144 purine nucleoside triphosphate metabolic process The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009150 purine ribonucleotide metabolic process http://purl.obolibrary.org/obo/GO_0009259 ribonucleotide metabolic process The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/GO_0009156 ribonucleoside monophosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0009161 ribonucleoside monophosphate metabolic process The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009161 ribonucleoside monophosphate metabolic process http://purl.obolibrary.org/obo/GO_0009123 nucleoside monophosphate metabolic process The chemical reactions and pathways involving a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009163 nucleoside biosynthetic process http://purl.obolibrary.org/obo/GO_1901659 glycosyl compound biosynthetic process The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside). http://purl.obolibrary.org/obo/GO_0009167 purine ribonucleoside monophosphate metabolic process http://purl.obolibrary.org/obo/GO_0009161 ribonucleoside monophosphate metabolic process The chemical reactions and pathways involving purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009199 ribonucleoside triphosphate metabolic process http://purl.obolibrary.org/obo/GO_0009141 nucleoside triphosphate metabolic process The chemical reactions and pathways involving a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009201 ribonucleoside triphosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0009199 ribonucleoside triphosphate metabolic process The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009205 purine ribonucleoside triphosphate metabolic process http://purl.obolibrary.org/obo/GO_0009199 ribonucleoside triphosphate metabolic process The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar. http://purl.obolibrary.org/obo/GO_0009235 cobalamin metabolic process http://purl.obolibrary.org/obo/GO_0017144 drug metabolic process The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. http://purl.obolibrary.org/obo/GO_0009259 ribonucleotide metabolic process http://purl.obolibrary.org/obo/GO_0019693 ribose phosphate metabolic process The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/GO_0009260 ribonucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0009259 ribonucleotide metabolic process The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar. http://purl.obolibrary.org/obo/GO_0009266 response to temperature stimulus http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. http://purl.obolibrary.org/obo/GO_0009268 response to pH http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution. http://purl.obolibrary.org/obo/GO_0009279 cell outer membrane http://purl.obolibrary.org/obo/GO_0019867 outer membrane A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures. http://purl.obolibrary.org/obo/GO_0009295 nucleoid http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined. http://purl.obolibrary.org/obo/GO_0009314 response to radiation http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. http://purl.obolibrary.org/obo/GO_0009372 quorum sensing http://purl.obolibrary.org/obo/GO_0060245 detection of cell density The cell-cell signaling process in which single-celled organisms carry out coordinated responses by monitoring their own population density, and often also that of other microbes, by producing small, diffusible, signal molecules, detecting the concentration of these molecules, and triggering a signal transduction pathway when a certain threshold is reached. Quorum sensing can occur amongst microbial communities in the environment or within host organisms. http://purl.obolibrary.org/obo/GO_0009409 response to cold http://purl.obolibrary.org/obo/GO_0009266 response to temperature stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. http://purl.obolibrary.org/obo/GO_0009410 response to xenobiotic stimulus http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms. http://purl.obolibrary.org/obo/GO_0009411 response to UV http://purl.obolibrary.org/obo/GO_0009416 response to light stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers. http://purl.obolibrary.org/obo/GO_0009414 response to water deprivation http://purl.obolibrary.org/obo/GO_0009415 response to water Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water. http://purl.obolibrary.org/obo/GO_0009415 response to water http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water. http://purl.obolibrary.org/obo/GO_0009453 energy taxis http://purl.obolibrary.org/obo/GO_0042330 taxis The directed movement of a motile cell or organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. http://purl.obolibrary.org/obo/GO_0009507 chloroplast http://purl.obolibrary.org/obo/GO_0009536 plastid A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. http://purl.obolibrary.org/obo/GO_0009526 plastid envelope http://purl.obolibrary.org/obo/GO_0031967 organelle envelope The double lipid bilayer enclosing a plastid and separating its contents from the rest of the cytoplasm; includes the intermembrane space. http://purl.obolibrary.org/obo/GO_0009532 plastid stroma http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity The proteinaceous ground substance of plastids. http://purl.obolibrary.org/obo/GO_0009533 chloroplast stromal thylakoid http://purl.obolibrary.org/obo/GO_0009534 chloroplast thylakoid Unstacked thylakoids that connect the grana stacks through the stroma. http://purl.obolibrary.org/obo/GO_0009534 chloroplast thylakoid http://purl.obolibrary.org/obo/GO_0031976 plastid thylakoid Sac-like membranous structures (cisternae) in a chloroplast combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. An example of this component is found in Arabidopsis thaliana. http://purl.obolibrary.org/obo/GO_0009537 proplastid http://purl.obolibrary.org/obo/GO_0009536 plastid The precursor of other plastids. http://purl.obolibrary.org/obo/GO_0009570 chloroplast stroma http://purl.obolibrary.org/obo/GO_0009532 plastid stroma The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis. http://purl.obolibrary.org/obo/GO_0009571 proplastid stroma http://purl.obolibrary.org/obo/GO_0009532 plastid stroma The space enclosed by the double membrane of a proplastid. http://purl.obolibrary.org/obo/GO_0009579 thylakoid http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical entity A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation. http://purl.obolibrary.org/obo/GO_0009581 detection of external stimulus http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events in which an external stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0009582 detection of abiotic stimulus http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0009615 response to virus http://purl.obolibrary.org/obo/GO_0051707 response to other organism Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus. http://purl.obolibrary.org/obo/GO_0009636 response to toxic substance http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus. http://purl.obolibrary.org/obo/GO_0009637 response to blue light http://purl.obolibrary.org/obo/GO_0009416 response to light stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. http://purl.obolibrary.org/obo/GO_0009639 response to red or far red light http://purl.obolibrary.org/obo/GO_0009416 response to light stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. http://purl.obolibrary.org/obo/GO_0009642 response to light intensity http://purl.obolibrary.org/obo/GO_0009416 response to light stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus. http://purl.obolibrary.org/obo/GO_0009644 response to high light intensity http://purl.obolibrary.org/obo/GO_0009642 response to light intensity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus. http://purl.obolibrary.org/obo/GO_0009645 response to low light intensity stimulus http://purl.obolibrary.org/obo/GO_0009642 response to light intensity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2. http://purl.obolibrary.org/obo/GO_0009646 response to absence of light http://purl.obolibrary.org/obo/GO_0009642 response to light intensity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli. http://purl.obolibrary.org/obo/GO_0009651 response to salt stress http://purl.obolibrary.org/obo/GO_0006970 response to osmotic stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. http://purl.obolibrary.org/obo/GO_0009719 response to endogenous stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. http://purl.obolibrary.org/obo/GO_0009725 response to hormone http://purl.obolibrary.org/obo/GO_0009719 response to endogenous stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. http://purl.obolibrary.org/obo/GO_0009785 blue light signaling pathway http://purl.obolibrary.org/obo/GO_0071483 cellular response to blue light The series of molecular signals initiated upon sensing of blue light by photoreceptor molecule, at a wavelength between 400nm and 470nm. http://purl.obolibrary.org/obo/GO_0009786 regulation of asymmetric cell division http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division Any process that modulates the frequency, rate or extent of asymmetric cell division. http://purl.obolibrary.org/obo/GO_0009790 embryo development http://purl.obolibrary.org/obo/GO_0007275 multicellular organism development The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. http://purl.obolibrary.org/obo/GO_0009856 pollination http://purl.obolibrary.org/obo/GO_0022414 reproductive process The cascade of biological processes occurring in plants beginning when the pollen lands on the female reproductive organs of a plant and continuing up to, but not including, fertilization, as defined by sperm-egg cell fusion. http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances. http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. http://purl.obolibrary.org/obo/GO_0009941 chloroplast envelope http://purl.obolibrary.org/obo/GO_0009526 plastid envelope The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space. http://purl.obolibrary.org/obo/GO_0009991 response to extracellular stimulus http://purl.obolibrary.org/obo/GO_0009605 response to external stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus. http://purl.obolibrary.org/obo/GO_0009994 oocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete. http://purl.obolibrary.org/obo/GO_0010017 red or far-red light signaling pathway http://purl.obolibrary.org/obo/GO_0071489 cellular response to red or far red light The series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. http://purl.obolibrary.org/obo/GO_0010018 far-red light signaling pathway http://purl.obolibrary.org/obo/GO_0071490 cellular response to far red light The series of molecular signals initiated upon sensing of far red light by a photoreceptor molecule. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. http://purl.obolibrary.org/obo/GO_0010032 meiotic chromosome condensation http://purl.obolibrary.org/obo/GO_0030261 chromosome condensation Compaction of chromatin structure prior to meiosis in eukaryotic cells. http://purl.obolibrary.org/obo/GO_0010038 response to metal ion http://purl.obolibrary.org/obo/GO_0010035 response to inorganic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. http://purl.obolibrary.org/obo/GO_0010114 response to red light http://purl.obolibrary.org/obo/GO_0009639 response to red or far red light Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. http://purl.obolibrary.org/obo/GO_0010161 red light signaling pathway http://purl.obolibrary.org/obo/GO_0071491 cellular response to red light The series of molecular signals initiated upon sensing of red light by a photoreceptor molecule. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. http://purl.obolibrary.org/obo/GO_0010165 response to X-ray http://purl.obolibrary.org/obo/GO_0010212 response to ionizing radiation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz). http://purl.obolibrary.org/obo/GO_0010185 regulation of cellular defense response http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that modulates the frequency, rate or extent of cellular defense response. http://purl.obolibrary.org/obo/GO_0010186 positive regulation of cellular defense response http://purl.obolibrary.org/obo/GO_0010185 regulation of cellular defense response Any process that activates or increases the frequency, rate or extent of cellular defense response. http://purl.obolibrary.org/obo/GO_0010212 response to ionizing radiation http://purl.obolibrary.org/obo/GO_0009314 response to radiation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays. http://purl.obolibrary.org/obo/GO_0010218 response to far red light http://purl.obolibrary.org/obo/GO_0009639 response to red or far red light Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. http://purl.obolibrary.org/obo/GO_0010224 response to UV-B http://purl.obolibrary.org/obo/GO_0009411 response to UV Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm. http://purl.obolibrary.org/obo/GO_0010225 response to UV-C http://purl.obolibrary.org/obo/GO_0009411 response to UV Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm. http://purl.obolibrary.org/obo/GO_0010226 response to lithium ion http://purl.obolibrary.org/obo/GO_0010038 response to metal ion Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus. http://purl.obolibrary.org/obo/GO_0010243 response to organonitrogen compound http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond. http://purl.obolibrary.org/obo/GO_0010332 response to gamma radiation http://purl.obolibrary.org/obo/GO_0010212 response to ionizing radiation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum. http://purl.obolibrary.org/obo/GO_0010466 negative regulation of peptidase activity http://purl.obolibrary.org/obo/GO_0052547 regulation of peptidase activity Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins. http://purl.obolibrary.org/obo/GO_0010506 regulation of autophagy http://purl.obolibrary.org/obo/GO_0031329 regulation of cellular catabolic process Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. http://purl.obolibrary.org/obo/GO_0010507 negative regulation of autophagy http://purl.obolibrary.org/obo/GO_0031330 negative regulation of cellular catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. http://purl.obolibrary.org/obo/GO_0010508 positive regulation of autophagy http://purl.obolibrary.org/obo/GO_0010506 regulation of autophagy Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. http://purl.obolibrary.org/obo/GO_0010543 regulation of platelet activation http://purl.obolibrary.org/obo/GO_0030193 regulation of blood coagulation Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. http://purl.obolibrary.org/obo/GO_0010544 negative regulation of platelet activation http://purl.obolibrary.org/obo/GO_0030195 negative regulation of blood coagulation Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. http://purl.obolibrary.org/obo/GO_0010559 regulation of glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0010560 positive regulation of glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_1903020 positive regulation of glycoprotein metabolic process Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0010561 negative regulation of glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_1903019 negative regulation of glycoprotein metabolic process Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0010562 positive regulation of phosphorus metabolic process http://purl.obolibrary.org/obo/GO_0051174 regulation of phosphorus metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. http://purl.obolibrary.org/obo/GO_0010563 negative regulation of phosphorus metabolic process http://purl.obolibrary.org/obo/GO_0051174 regulation of phosphorus metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. http://purl.obolibrary.org/obo/GO_0010572 positive regulation of platelet activation http://purl.obolibrary.org/obo/GO_0010543 regulation of platelet activation Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. http://purl.obolibrary.org/obo/GO_0010623 programmed cell death involved in cell development http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The activation of endogenous cellular processes that result in the death of a cell as part of its development. http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression http://purl.obolibrary.org/obo/GO_0010604 positive regulation of macromolecule metabolic process Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication http://purl.obolibrary.org/obo/GO_0010646 regulation of cell communication Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0010672 regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle http://purl.obolibrary.org/obo/GO_0051037 regulation of transcription involved in meiotic cell cycle Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0010673 positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle http://purl.obolibrary.org/obo/GO_0051039 positive regulation of transcription involved in meiotic cell cycle Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0010674 negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle http://purl.obolibrary.org/obo/GO_0051038 negative regulation of transcription involved in meiotic cell cycle Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage http://purl.obolibrary.org/obo/GO_0043618 regulation of transcription from RNA polymerase II promoter in response to stress Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus. http://purl.obolibrary.org/obo/GO_0010768 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage http://purl.obolibrary.org/obo/GO_0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus. http://purl.obolibrary.org/obo/GO_0010821 regulation of mitochondrion organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion. http://purl.obolibrary.org/obo/GO_0010822 positive regulation of mitochondrion organization http://purl.obolibrary.org/obo/GO_0010821 regulation of mitochondrion organization Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion. http://purl.obolibrary.org/obo/GO_0010823 negative regulation of mitochondrion organization http://purl.obolibrary.org/obo/GO_0010821 regulation of mitochondrion organization Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion. http://purl.obolibrary.org/obo/GO_0010941 regulation of cell death http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. http://purl.obolibrary.org/obo/GO_0010942 positive regulation of cell death http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process http://purl.obolibrary.org/obo/GO_0045786 negative regulation of cell cycle Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. http://purl.obolibrary.org/obo/GO_0010952 positive regulation of peptidase activity http://purl.obolibrary.org/obo/GO_0052547 regulation of peptidase activity Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins. http://purl.obolibrary.org/obo/GO_0010960 magnesium ion homeostasis http://purl.obolibrary.org/obo/GO_0072507 divalent inorganic cation homeostasis Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell. http://purl.obolibrary.org/obo/GO_0010975 regulation of neuron projection development http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/GO_0010976 positive regulation of neuron projection development http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/GO_0010977 negative regulation of neuron projection development http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/GO_0012506 vesicle membrane http://purl.obolibrary.org/obo/GO_0031090 organelle membrane The lipid bilayer surrounding any membrane-bounded vesicle in the cell. http://purl.obolibrary.org/obo/GO_0012507 ER to Golgi transport vesicle membrane http://purl.obolibrary.org/obo/GO_0030662 coated vesicle membrane The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi. http://purl.obolibrary.org/obo/GO_0012511 monolayer-surrounded lipid storage body http://purl.obolibrary.org/obo/GO_0005811 lipid droplet A subcellular organelle of plant cells surrounded by 'half-unit' or a monolayer membrane instead of the more usual bilayer. The storage body has a droplet of triglyceride surrounded by a monolayer of phospholipids, interacting with the triglycerides and the hydrophilic head groups facing the cytosol, and containing major protein components called oleosins. http://purl.obolibrary.org/obo/GO_0014041 regulation of neuron maturation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change. http://purl.obolibrary.org/obo/GO_0014042 positive regulation of neuron maturation http://purl.obolibrary.org/obo/GO_1903431 positive regulation of cell maturation Any process that activates or increases the frequency, rate or extent of neuron maturation. http://purl.obolibrary.org/obo/GO_0014043 negative regulation of neuron maturation http://purl.obolibrary.org/obo/GO_1903430 negative regulation of cell maturation Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation. http://purl.obolibrary.org/obo/GO_0014069 postsynaptic density http://purl.obolibrary.org/obo/GO_0099572 postsynaptic specialization An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. http://purl.obolibrary.org/obo/GO_0014070 response to organic cyclic compound http://purl.obolibrary.org/obo/GO_0010033 response to organic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus. http://purl.obolibrary.org/obo/GO_0014072 response to isoquinoline alkaloid http://purl.obolibrary.org/obo/GO_0043279 response to alkaloid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids. http://purl.obolibrary.org/obo/GO_0015318 inorganic molecular entity transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon. http://purl.obolibrary.org/obo/GO_0015849 organic acid transport http://purl.obolibrary.org/obo/GO_0071702 organic substance transport The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015884 folic acid transport http://purl.obolibrary.org/obo/GO_0072337 modified amino acid transport The directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines. http://purl.obolibrary.org/obo/GO_0016056 rhodopsin mediated signaling pathway http://purl.obolibrary.org/obo/GO_0071482 cellular response to light stimulus The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon and the events that convert the absorbed photons into a cellular response. http://purl.obolibrary.org/obo/GO_0016119 carotene metabolic process http://purl.obolibrary.org/obo/GO_0042214 terpene metabolic process The chemical reactions and pathways involving carotenes, hydrocarbon carotenoids. http://purl.obolibrary.org/obo/GO_0016239 positive regulation of macroautophagy http://purl.obolibrary.org/obo/GO_0016241 regulation of macroautophagy Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation. http://purl.obolibrary.org/obo/GO_0016241 regulation of macroautophagy http://purl.obolibrary.org/obo/GO_0010506 regulation of autophagy Any process that modulates the frequency, rate or extent of macroautophagy. http://purl.obolibrary.org/obo/GO_0016242 negative regulation of macroautophagy http://purl.obolibrary.org/obo/GO_0016241 regulation of macroautophagy Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy. http://purl.obolibrary.org/obo/GO_0016246 RNA interference http://purl.obolibrary.org/obo/GO_0035194 posttranscriptional gene silencing by RNA The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes. http://purl.obolibrary.org/obo/GO_0016321 female meiosis chromosome segregation http://purl.obolibrary.org/obo/GO_0022412 cellular process involved in reproduction in multicellular organism The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female. http://purl.obolibrary.org/obo/GO_0016441 posttranscriptional gene silencing http://purl.obolibrary.org/obo/GO_0040029 regulation of gene expression, epigenetic The inactivation of gene expression by a posttranscriptional mechanism. http://purl.obolibrary.org/obo/GO_0016525 negative regulation of angiogenesis http://purl.obolibrary.org/obo/GO_2000181 negative regulation of blood vessel morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis. http://purl.obolibrary.org/obo/GO_0016772 transferase activity, transferring phosphorus-containing groups http://purl.obolibrary.org/obo/GO_0016740 transferase activity Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). http://purl.obolibrary.org/obo/GO_0016877 ligase activity, forming carbon-sulfur bonds http://purl.obolibrary.org/obo/GO_0016874 ligase activity Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. http://purl.obolibrary.org/obo/GO_0016922 nuclear receptor binding http://purl.obolibrary.org/obo/GO_0035257 nuclear hormone receptor binding Interacting selectively and non-covalently, in a ligand dependent manner, with a nuclear receptor protein. http://purl.obolibrary.org/obo/GO_0017144 drug metabolic process http://purl.obolibrary.org/obo/GO_0044237 cellular metabolic process The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice. http://purl.obolibrary.org/obo/GO_0017145 stem cell division http://purl.obolibrary.org/obo/GO_0051301 cell division The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types. http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. http://purl.obolibrary.org/obo/GO_0019783 ubiquitin-like protein-specific protease activity http://purl.obolibrary.org/obo/GO_0008234 cysteine-type peptidase activity Catalysis of the hydrolysis of peptide or isopeptide bonds within small proteins such as ubiquitin or ubiquitin-like proteins (e.g. APG8, ISG15, NEDD8, SUMO), or between the small protein and a larger protein to which it has been conjugated. http://purl.obolibrary.org/obo/GO_0019867 outer membrane http://purl.obolibrary.org/obo/GO_0016020 membrane The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites. http://purl.obolibrary.org/obo/GO_0022400 regulation of rhodopsin mediated signaling pathway http://purl.obolibrary.org/obo/GO_0008277 regulation of G protein-coupled receptor signaling pathway Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling. http://purl.obolibrary.org/obo/GO_0022406 membrane docking http://purl.obolibrary.org/obo/GO_0009987 cellular process The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere. http://purl.obolibrary.org/obo/GO_0030134 COPII-coated ER to Golgi transport vesicle http://purl.obolibrary.org/obo/GO_0030135 coated vesicle A vesicle with a coat formed of the COPII coat complex proteins. The COPII coat complex is formed by the Sec23p/Sec24p and the Sec13p/Sec31p heterodimers. COPII-associated vesicles transport proteins from the rough endoplasmic reticulum to the Golgi apparatus (anterograde transport). http://purl.obolibrary.org/obo/GO_0030168 platelet activation http://purl.obolibrary.org/obo/GO_0001775 cell activation A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug. http://purl.obolibrary.org/obo/GO_0030193 regulation of blood coagulation http://purl.obolibrary.org/obo/GO_1900046 regulation of hemostasis Any process that modulates the frequency, rate or extent of blood coagulation. http://purl.obolibrary.org/obo/GO_0030195 negative regulation of blood coagulation http://purl.obolibrary.org/obo/GO_0030193 regulation of blood coagulation Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation. http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization http://purl.obolibrary.org/obo/GO_0043062 extracellular structure organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix. http://purl.obolibrary.org/obo/GO_0030313 cell envelope http://purl.obolibrary.org/obo/GO_0031975 envelope An envelope that surrounds a bacterial cell and includes the cytoplasmic membrane and everything external, encompassing the periplasmic space, cell wall, and outer membrane if present. http://purl.obolibrary.org/obo/GO_0030546 signaling receptor activator activity http://purl.obolibrary.org/obo/GO_0030545 receptor regulator activity The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased. http://purl.obolibrary.org/obo/GO_0030658 transport vesicle membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a transport vesicle. http://purl.obolibrary.org/obo/GO_0030660 Golgi-associated vesicle membrane http://purl.obolibrary.org/obo/GO_0098588 bounding membrane of organelle The lipid bilayer surrounding a vesicle associated with the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0030662 coated vesicle membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a coated vesicle. http://purl.obolibrary.org/obo/GO_0030705 cytoskeleton-dependent intracellular transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell. http://purl.obolibrary.org/obo/GO_0031090 organelle membrane http://purl.obolibrary.org/obo/GO_0016020 membrane A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. http://purl.obolibrary.org/obo/GO_0031330 negative regulation of cellular catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. http://purl.obolibrary.org/obo/GO_0031344 regulation of cell projection organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. http://purl.obolibrary.org/obo/GO_0031346 positive regulation of cell projection organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of a defense response. http://purl.obolibrary.org/obo/GO_0031669 cellular response to nutrient levels http://purl.obolibrary.org/obo/GO_0031668 cellular response to extracellular stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients. http://purl.obolibrary.org/obo/GO_0031969 chloroplast membrane http://purl.obolibrary.org/obo/GO_0042170 plastid membrane Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope. http://purl.obolibrary.org/obo/GO_0031976 plastid thylakoid http://purl.obolibrary.org/obo/GO_0009579 thylakoid Any thylakoid within a plastid. http://purl.obolibrary.org/obo/GO_0031982 vesicle http://purl.obolibrary.org/obo/GO_0043227 membrane-bounded organelle Any small, fluid-filled, spherical organelle enclosed by membrane. http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus. http://purl.obolibrary.org/obo/GO_0032108 negative regulation of response to nutrient levels http://purl.obolibrary.org/obo/GO_0032107 regulation of response to nutrient levels Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels. http://purl.obolibrary.org/obo/GO_0032269 negative regulation of cellular protein metabolic process http://purl.obolibrary.org/obo/GO_0051248 negative regulation of protein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell. http://purl.obolibrary.org/obo/GO_0032279 asymmetric synapse http://purl.obolibrary.org/obo/GO_0098984 neuron to neuron synapse A type of synapse occurring between an axon and a dendritic spine or dendritic shaft. Asymmetric synapses, the most abundant synapse type in the central nervous system, involve axons that contain predominantly spherical vesicles and contain a thickened postsynaptic density. Most or all synapses of this type are excitatory. http://purl.obolibrary.org/obo/GO_0032412 regulation of ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022898 regulation of transmembrane transporter activity Any process that modulates the activity of an ion transporter. http://purl.obolibrary.org/obo/GO_0032413 negative regulation of ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0032412 regulation of ion transmembrane transporter activity Any process that stops or reduces the activity of an ion transporter. http://purl.obolibrary.org/obo/GO_0032870 cellular response to hormone stimulus http://purl.obolibrary.org/obo/GO_0009725 response to hormone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. http://purl.obolibrary.org/obo/GO_0032879 regulation of localization http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0033047 regulation of mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0033045 regulation of sister chromatid segregation Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis. http://purl.obolibrary.org/obo/GO_0033273 response to vitamin http://purl.obolibrary.org/obo/GO_0007584 response to nutrient Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus. http://purl.obolibrary.org/obo/GO_0033993 response to lipid http://purl.obolibrary.org/obo/GO_0010033 response to organic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. http://purl.obolibrary.org/obo/GO_0034220 ion transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport A process in which an ion is transported across a membrane. http://purl.obolibrary.org/obo/GO_0034654 nucleobase-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_1901362 organic cyclic compound biosynthetic process The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0035194 posttranscriptional gene silencing by RNA http://purl.obolibrary.org/obo/GO_0016441 posttranscriptional gene silencing Any process of posttranscriptional gene inactivation (silencing) mediated by small RNA molecules that may trigger RNA (often mRNA) degradation or negatively regulate mRNA translation. http://purl.obolibrary.org/obo/GO_0035461 vitamin transmembrane transport http://purl.obolibrary.org/obo/GO_0051180 vitamin transport The process in which a vitamin is transported across a membrane. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. http://purl.obolibrary.org/obo/GO_0036276 response to antidepressant http://purl.obolibrary.org/obo/GO_0042493 response to drug Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug. http://purl.obolibrary.org/obo/GO_0042048 olfactory behavior http://purl.obolibrary.org/obo/GO_0007635 chemosensory behavior The behavior of an organism in response to an odor. http://purl.obolibrary.org/obo/GO_0042170 plastid membrane http://purl.obolibrary.org/obo/GO_0031090 organelle membrane Either of the lipid bilayers that surround a plastid and form the plastid envelope. http://purl.obolibrary.org/obo/GO_0042214 terpene metabolic process http://purl.obolibrary.org/obo/GO_0006720 isoprenoid metabolic process The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups. http://purl.obolibrary.org/obo/GO_0042360 vitamin E metabolic process http://purl.obolibrary.org/obo/GO_1901360 organic cyclic compound metabolic process The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant. http://purl.obolibrary.org/obo/GO_0042455 ribonucleoside biosynthetic process http://purl.obolibrary.org/obo/GO_0009163 nucleoside biosynthetic process The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule. http://purl.obolibrary.org/obo/GO_0042493 response to drug http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease. http://purl.obolibrary.org/obo/GO_0042551 neuron maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0042594 response to starvation http://purl.obolibrary.org/obo/GO_0031667 response to nutrient levels Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment. http://purl.obolibrary.org/obo/GO_0042646 plastid nucleoid http://purl.obolibrary.org/obo/GO_0009295 nucleoid The region of a plastid to which the DNA is confined. http://purl.obolibrary.org/obo/GO_0042749 regulation of circadian sleep/wake cycle http://purl.obolibrary.org/obo/GO_0042752 regulation of circadian rhythm Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle. http://purl.obolibrary.org/obo/GO_0042752 regulation of circadian rhythm http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours. http://purl.obolibrary.org/obo/GO_0042753 positive regulation of circadian rhythm http://purl.obolibrary.org/obo/GO_0042752 regulation of circadian rhythm Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior. http://purl.obolibrary.org/obo/GO_0042762 regulation of sulfur metabolic process http://purl.obolibrary.org/obo/GO_0031323 regulation of cellular metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur. http://purl.obolibrary.org/obo/GO_0042908 xenobiotic transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of a xenobiotic, a compound foreign to living organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0042910 xenobiotic transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical. http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process http://purl.obolibrary.org/obo/GO_0043068 positive regulation of programmed cell death Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death http://purl.obolibrary.org/obo/GO_0010941 regulation of cell death Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. http://purl.obolibrary.org/obo/GO_0043068 positive regulation of programmed cell death http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. http://purl.obolibrary.org/obo/GO_0043228 non-membrane-bounded organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes. http://purl.obolibrary.org/obo/GO_0043269 regulation of ion transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0043270 positive regulation of ion transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0043271 negative regulation of ion transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0043279 response to alkaloid http://purl.obolibrary.org/obo/GO_0010243 response to organonitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active. http://purl.obolibrary.org/obo/GO_0043618 regulation of transcription from RNA polymerase II promoter in response to stress http://purl.obolibrary.org/obo/GO_0043620 regulation of DNA-templated transcription in response to stress Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_0043901 negative regulation of multi-organism process http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species. http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis http://purl.obolibrary.org/obo/GO_0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. http://purl.obolibrary.org/obo/GO_0044111 development involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0051704 multi-organism process The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0044403 symbiosis, encompassing mutualism through parasitism http://purl.obolibrary.org/obo/GO_0044419 interspecies interaction between organisms A process carried out by gene products in an organism that enable the organism to engage in a symbiotic relationship, a more or less intimate association, with another organism. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts. http://purl.obolibrary.org/obo/GO_0044419 interspecies interaction between organisms http://purl.obolibrary.org/obo/GO_0051704 multi-organism process Any process in which an organism has an effect on an organism of a different species. http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization http://purl.obolibrary.org/obo/GO_0051234 establishment of localization The directed movement of a protein to a specific location. http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features. http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell differentiation. http://purl.obolibrary.org/obo/GO_0045646 regulation of erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the frequency, rate or extent of erythrocyte differentiation. http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis Any process that modulates the frequency, rate or extent of neuron differentiation. http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation. http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of neuron differentiation. http://purl.obolibrary.org/obo/GO_0045765 regulation of angiogenesis http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development Any process that modulates the frequency, rate or extent of angiogenesis. http://purl.obolibrary.org/obo/GO_0045785 positive regulation of cell adhesion http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell adhesion. http://purl.obolibrary.org/obo/GO_0045827 negative regulation of isoprenoid metabolic process http://purl.obolibrary.org/obo/GO_0031324 negative regulation of cellular metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid. http://purl.obolibrary.org/obo/GO_0045828 positive regulation of isoprenoid metabolic process http://purl.obolibrary.org/obo/GO_0031325 positive regulation of cellular metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid. http://purl.obolibrary.org/obo/GO_0045861 negative regulation of proteolysis http://purl.obolibrary.org/obo/GO_0032269 negative regulation of cellular protein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. http://purl.obolibrary.org/obo/GO_0045862 positive regulation of proteolysis http://purl.obolibrary.org/obo/GO_0032270 positive regulation of cellular protein metabolic process Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. http://purl.obolibrary.org/obo/GO_0045913 positive regulation of carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. http://purl.obolibrary.org/obo/GO_0045934 negative regulation of nucleobase-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0051172 negative regulation of nitrogen compound metabolic process Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0045936 negative regulation of phosphate metabolic process http://purl.obolibrary.org/obo/GO_0010563 negative regulation of phosphorus metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates. http://purl.obolibrary.org/obo/GO_0046137 negative regulation of vitamin metabolic process http://purl.obolibrary.org/obo/GO_0030656 regulation of vitamin metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. http://purl.obolibrary.org/obo/GO_0048520 positive regulation of behavior http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of developmental growth. http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis http://purl.obolibrary.org/obo/GO_0042592 homeostatic process Any biological process involved in the maintenance of an internal steady state of a chemical. http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system. http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the activity of an enzyme. http://purl.obolibrary.org/obo/GO_0051037 regulation of transcription involved in meiotic cell cycle http://purl.obolibrary.org/obo/GO_0022414 reproductive process Any process that modulates the frequency, rate or extent of transcription as part of a meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051038 negative regulation of transcription involved in meiotic cell cycle http://purl.obolibrary.org/obo/GO_0051037 regulation of transcription involved in meiotic cell cycle Any process that stops, prevents, or reduces the frequency, rate or extent of transcription involved in the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051039 positive regulation of transcription involved in meiotic cell cycle http://purl.obolibrary.org/obo/GO_0051037 regulation of transcription involved in meiotic cell cycle Any process that activates or increases the frequency, rate or extent of transcription as part of a meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051049 regulation of transport http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. http://purl.obolibrary.org/obo/GO_0051171 regulation of nitrogen compound metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. http://purl.obolibrary.org/obo/GO_0051172 negative regulation of nitrogen compound metabolic process http://purl.obolibrary.org/obo/GO_0051171 regulation of nitrogen compound metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. http://purl.obolibrary.org/obo/GO_0051174 regulation of phosphorus metabolic process http://purl.obolibrary.org/obo/GO_0031323 regulation of cellular metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. http://purl.obolibrary.org/obo/GO_0051176 positive regulation of sulfur metabolic process http://purl.obolibrary.org/obo/GO_0042762 regulation of sulfur metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur. http://purl.obolibrary.org/obo/GO_0051180 vitamin transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. http://purl.obolibrary.org/obo/GO_0051336 regulation of hydrolase activity http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. http://purl.obolibrary.org/obo/GO_0051345 positive regulation of hydrolase activity http://purl.obolibrary.org/obo/GO_0051336 regulation of hydrolase activity Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds. http://purl.obolibrary.org/obo/GO_0051346 negative regulation of hydrolase activity http://purl.obolibrary.org/obo/GO_0051336 regulation of hydrolase activity Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds. http://purl.obolibrary.org/obo/GO_0051494 negative regulation of cytoskeleton organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0051495 positive regulation of cytoskeleton organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0051640 organelle localization http://purl.obolibrary.org/obo/GO_0051641 cellular localization Any process in which an organelle is transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0051703 intraspecies interaction between organisms http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process in which an organism has an effect on an organism of the same species. http://purl.obolibrary.org/obo/GO_0052042 positive regulation by symbiont of host programmed cell death http://purl.obolibrary.org/obo/GO_0052330 positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052547 regulation of peptidase activity http://purl.obolibrary.org/obo/GO_0051336 regulation of hydrolase activity Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins. http://purl.obolibrary.org/obo/GO_0055081 anion homeostasis http://purl.obolibrary.org/obo/GO_0050801 ion homeostasis Any process involved in the maintenance of an internal steady state of anions within an organism or cell. http://purl.obolibrary.org/obo/GO_0055122 response to very low light intensity stimulus http://purl.obolibrary.org/obo/GO_0009642 response to light intensity Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec. http://purl.obolibrary.org/obo/GO_0060049 regulation of protein glycosylation http://purl.obolibrary.org/obo/GO_0010559 regulation of glycoprotein biosynthetic process Any process that modulates the frequency, rate or extent of protein glycosylation. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins. http://purl.obolibrary.org/obo/GO_0060051 negative regulation of protein glycosylation http://purl.obolibrary.org/obo/GO_0060049 regulation of protein glycosylation Any process that stops, prevents, or reduces the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins. http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell. http://purl.obolibrary.org/obo/GO_0060491 regulation of cell projection assembly http://purl.obolibrary.org/obo/GO_0031344 regulation of cell projection organization Any process that modulates the rate, frequency, or extent of cell projection assembly. http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell. http://purl.obolibrary.org/obo/GO_0060966 regulation of gene silencing by RNA http://purl.obolibrary.org/obo/GO_0060968 regulation of gene silencing Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes. http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. http://purl.obolibrary.org/obo/GO_0070507 regulation of microtubule cytoskeleton organization http://purl.obolibrary.org/obo/GO_0032886 regulation of microtubule-based process Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. http://purl.obolibrary.org/obo/GO_0070727 cellular macromolecule localization http://purl.obolibrary.org/obo/GO_0051641 cellular localization Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. http://purl.obolibrary.org/obo/GO_0071482 cellular response to light stimulus http://purl.obolibrary.org/obo/GO_0071478 cellular response to radiation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light. http://purl.obolibrary.org/obo/GO_0071483 cellular response to blue light http://purl.obolibrary.org/obo/GO_0071482 cellular response to light stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. http://purl.obolibrary.org/obo/GO_0071489 cellular response to red or far red light http://purl.obolibrary.org/obo/GO_0071482 cellular response to light stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. http://purl.obolibrary.org/obo/GO_0071490 cellular response to far red light http://purl.obolibrary.org/obo/GO_0071489 cellular response to red or far red light Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. http://purl.obolibrary.org/obo/GO_0071491 cellular response to red light http://purl.obolibrary.org/obo/GO_0071489 cellular response to red or far red light Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs. http://purl.obolibrary.org/obo/GO_0071840 cellular component organization or biogenesis http://purl.obolibrary.org/obo/GO_0009987 cellular process A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. http://purl.obolibrary.org/obo/GO_0072337 modified amino acid transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0072507 divalent inorganic cation homeostasis http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis Any process involved in the maintenance of an internal steady state of divalent cations within an organism or cell. http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process http://purl.obolibrary.org/obo/GO_0045787 positive regulation of cell cycle Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. http://purl.obolibrary.org/obo/GO_0090482 vitamin transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a vitamin from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0097305 response to alcohol http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus. http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region http://purl.obolibrary.org/obo/GO_0016020 membrane A membrane that is a (regional) part of the plasma membrane. http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion http://purl.obolibrary.org/obo/GO_0007155 cell adhesion The attachment of one cell to another cell via adhesion molecules. http://purl.obolibrary.org/obo/GO_0098656 anion transmembrane transport http://purl.obolibrary.org/obo/GO_0034220 ion transmembrane transport The process in which an anion is transported across a membrane. http://purl.obolibrary.org/obo/GO_0098827 endoplasmic reticulum subcompartment http://purl.obolibrary.org/obo/GO_0031984 organelle subcompartment A distinct region of the endoplasmic reticulum http://purl.obolibrary.org/obo/GO_0099003 vesicle-mediated transport in synapse http://purl.obolibrary.org/obo/GO_0016192 vesicle-mediated transport Any vesicle-mediated transport that occurs in a synapse http://purl.obolibrary.org/obo/GO_0099111 microtubule-based transport http://purl.obolibrary.org/obo/GO_0007018 microtubule-based movement A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. http://purl.obolibrary.org/obo/GO_0099572 postsynaptic specialization http://purl.obolibrary.org/obo/GO_0043226 organelle A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. http://purl.obolibrary.org/obo/GO_1901293 nucleoside phosphate biosynthetic process http://purl.obolibrary.org/obo/GO_0034654 nucleobase-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleoside phosphate. http://purl.obolibrary.org/obo/GO_1901419 regulation of response to alcohol http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of response to alcohol. http://purl.obolibrary.org/obo/GO_1901420 negative regulation of response to alcohol http://purl.obolibrary.org/obo/GO_1901419 regulation of response to alcohol Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol. http://purl.obolibrary.org/obo/GO_1901421 positive regulation of response to alcohol http://purl.obolibrary.org/obo/GO_1901419 regulation of response to alcohol Any process that activates or increases the frequency, rate or extent of response to alcohol. http://purl.obolibrary.org/obo/GO_1901657 glycosyl compound metabolic process http://purl.obolibrary.org/obo/GO_1901135 carbohydrate derivative metabolic process The chemical reactions and pathways involving glycosyl compound. http://purl.obolibrary.org/obo/GO_1901659 glycosyl compound biosynthetic process http://purl.obolibrary.org/obo/GO_1901657 glycosyl compound metabolic process The chemical reactions and pathways resulting in the formation of glycosyl compound. http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus. http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of organelle assembly. http://purl.obolibrary.org/obo/GO_1902116 negative regulation of organelle assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly. http://purl.obolibrary.org/obo/GO_1902117 positive regulation of organelle assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that activates or increases the frequency, rate or extent of organelle assembly. http://purl.obolibrary.org/obo/GO_1902531 regulation of intracellular signal transduction http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction Any process that modulates the frequency, rate or extent of intracellular signal transduction. http://purl.obolibrary.org/obo/GO_1902532 negative regulation of intracellular signal transduction http://purl.obolibrary.org/obo/GO_1902531 regulation of intracellular signal transduction Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction. http://purl.obolibrary.org/obo/GO_1902533 positive regulation of intracellular signal transduction http://purl.obolibrary.org/obo/GO_1902531 regulation of intracellular signal transduction Any process that activates or increases the frequency, rate or extent of intracellular signal transduction. http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of glycoprotein metabolic process. http://purl.obolibrary.org/obo/GO_1903019 negative regulation of glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process. http://purl.obolibrary.org/obo/GO_1903020 positive regulation of glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process. http://purl.obolibrary.org/obo/GO_1903430 negative regulation of cell maturation http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation. http://purl.obolibrary.org/obo/GO_1903431 positive regulation of cell maturation http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of cell maturation. http://purl.obolibrary.org/obo/GO_1903828 negative regulation of cellular protein localization http://purl.obolibrary.org/obo/GO_1903827 regulation of cellular protein localization Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. http://purl.obolibrary.org/obo/GO_1903959 regulation of anion transmembrane transport http://purl.obolibrary.org/obo/GO_0044070 regulation of anion transport Any process that modulates the frequency, rate or extent of anion transmembrane transport. http://purl.obolibrary.org/obo/GO_1903960 negative regulation of anion transmembrane transport http://purl.obolibrary.org/obo/GO_1903959 regulation of anion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of anion transmembrane transport. http://purl.obolibrary.org/obo/GO_1903961 positive regulation of anion transmembrane transport http://purl.obolibrary.org/obo/GO_1903959 regulation of anion transmembrane transport Any process that activates or increases the frequency, rate or extent of anion transmembrane transport. http://purl.obolibrary.org/obo/GO_2000030 regulation of response to red or far red light http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of response to red or far red light. http://purl.obolibrary.org/obo/GO_2000181 negative regulation of blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_1901343 negative regulation of vasculature development Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis. http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of reproductive process. http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process. http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that activates or increases the frequency, rate or extent of reproductive process. http://purl.obolibrary.org/obo/GO_0052054 negative regulation by symbiont of host peptidase activity http://purl.obolibrary.org/obo/GO_0052180 negative regulation of peptidase activity in other organism involved in symbiotic interaction Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host protease activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052149 modulation by symbiont of host peptidase activity http://purl.obolibrary.org/obo/GO_0052198 modulation of peptidase activity in other organism involved in symbiotic interaction The process in which an organism effects a change in host peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052180 negative regulation of peptidase activity in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protease activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052198 modulation of peptidase activity in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052203 modulation of catalytic activity in other organism involved in symbiotic interaction The process in which an organism effects a change in peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052204 negative regulation of molecular function in other organism involved in symbiotic interaction Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052205 modulation of molecular function in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0051817 modulation of process of other organism involved in symbiotic interaction The process in which an organism effects a change in the function of proteins in a second organism, where the two organisms are in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052230 modulation of intracellular transport in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0051817 modulation of process of other organism involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of a second organism, where the two organisms are in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052248 modulation of programmed cell death in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0051817 modulation of process of other organism involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of programmed cell death in a second organism, where the two organisms are in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052330 positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052248 modulation of programmed cell death in other organism involved in symbiotic interaction Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in a second organism, where the two organisms are in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052433 modulation by organism of apoptotic process in other organism involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0052248 modulation of programmed cell death in other organism involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent of programmed cell death by apoptosis in a second organism, where the two organisms are in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0060050 positive regulation of protein glycosylation http://purl.obolibrary.org/obo/GO_0060049 regulation of protein glycosylation Any process that activates or increases the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins. http://purl.obolibrary.org/obo/GO_0060054 positive regulation of epithelial cell proliferation involved in wound healing http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury. http://purl.obolibrary.org/obo/GO_0060055 angiogenesis involved in wound healing http://purl.obolibrary.org/obo/GO_0001525 angiogenesis Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury. http://purl.obolibrary.org/obo/GO_0060073 micturition http://purl.obolibrary.org/obo/GO_0003014 renal system process The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body. http://purl.obolibrary.org/obo/GO_0060147 regulation of posttranscriptional gene silencing http://purl.obolibrary.org/obo/GO_0060968 regulation of gene silencing Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism. http://purl.obolibrary.org/obo/GO_0060148 positive regulation of posttranscriptional gene silencing http://purl.obolibrary.org/obo/GO_0060147 regulation of posttranscriptional gene silencing Any process that increases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism. http://purl.obolibrary.org/obo/GO_0060149 negative regulation of posttranscriptional gene silencing http://purl.obolibrary.org/obo/GO_0060147 regulation of posttranscriptional gene silencing Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism. http://purl.obolibrary.org/obo/GO_0060245 detection of cell density http://purl.obolibrary.org/obo/GO_0009595 detection of biotic stimulus The series of events in which information about the density of cells in a population is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0060259 regulation of feeding behavior http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food. http://purl.obolibrary.org/obo/GO_0060278 regulation of ovulation http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary. http://purl.obolibrary.org/obo/GO_0060279 positive regulation of ovulation http://purl.obolibrary.org/obo/GO_0060278 regulation of ovulation Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary. http://purl.obolibrary.org/obo/GO_0060280 negative regulation of ovulation http://purl.obolibrary.org/obo/GO_0060278 regulation of ovulation Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary. http://purl.obolibrary.org/obo/GO_0060285 cilium-dependent cell motility http://purl.obolibrary.org/obo/GO_0001539 cilium or flagellum-dependent cell motility Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. http://purl.obolibrary.org/obo/GO_0060294 cilium movement involved in cell motility http://purl.obolibrary.org/obo/GO_0003341 cilium movement Movement of cilia mediated by motor proteins that contributes to the movement of a cell. http://purl.obolibrary.org/obo/GO_0060295 regulation of cilium movement involved in cell motility http://purl.obolibrary.org/obo/GO_1902019 regulation of cilium-dependent cell motility Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility. http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation http://purl.obolibrary.org/obo/GO_0033044 regulation of chromosome organization Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells. http://purl.obolibrary.org/obo/GO_0060967 negative regulation of gene silencing by RNA http://purl.obolibrary.org/obo/GO_0060966 regulation of gene silencing by RNA Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes. http://purl.obolibrary.org/obo/GO_0061044 negative regulation of vascular wound healing http://purl.obolibrary.org/obo/GO_0016525 negative regulation of angiogenesis Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature. http://purl.obolibrary.org/obo/GO_0061476 response to anticoagulant http://purl.obolibrary.org/obo/GO_0042493 response to drug Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticoagulant stimulus. http://purl.obolibrary.org/obo/GO_0061477 response to aromatase inhibitor http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aromatase inhibitor stimulus. http://purl.obolibrary.org/obo/GO_0061478 response to platelet aggregation inhibitor http://purl.obolibrary.org/obo/GO_0042493 response to drug Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet aggregation inhibitor stimulus. http://purl.obolibrary.org/obo/GO_0061479 response to reverse transcriptase inhibitor http://purl.obolibrary.org/obo/GO_0046677 response to antibiotic Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reverse transcriptase inhibitor stimulus. http://purl.obolibrary.org/obo/GO_0061512 protein localization to cilium http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within a cilium. http://purl.obolibrary.org/obo/GO_0061629 RNA polymerase II-specific DNA-binding transcription factor binding http://purl.obolibrary.org/obo/GO_0140297 DNA-binding transcription factor binding Interacting selectively and non-covalently with a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription. http://purl.obolibrary.org/obo/GO_0061650 ubiquitin-like protein conjugating enzyme activity http://purl.obolibrary.org/obo/GO_0019787 ubiquitin-like protein transferase activity Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another via the reaction X-SCP + Y -> Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue. http://purl.obolibrary.org/obo/GO_0061659 ubiquitin-like protein ligase activity http://purl.obolibrary.org/obo/GO_0019787 ubiquitin-like protein transferase activity Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S --> X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate. http://purl.obolibrary.org/obo/GO_0061736 engulfment of target by autophagosome http://purl.obolibrary.org/obo/GO_0010324 membrane invagination The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy. http://purl.obolibrary.org/obo/GO_0061743 motor learning http://purl.obolibrary.org/obo/GO_0007612 learning Any process in which an organism acquires a novel neuromuscular action or movement as the result of experience. http://purl.obolibrary.org/obo/GO_0061804 mitotic spindle formation (spindle phase one) http://purl.obolibrary.org/obo/GO_0007052 mitotic spindle organization The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase. http://purl.obolibrary.org/obo/GO_0070062 extracellular exosome http://purl.obolibrary.org/obo/GO_1903561 extracellular vesicle A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. http://purl.obolibrary.org/obo/GO_0070141 response to UV-A http://purl.obolibrary.org/obo/GO_0009411 response to UV Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm. http://purl.obolibrary.org/obo/GO_0070527 platelet aggregation http://purl.obolibrary.org/obo/GO_0034109 homotypic cell-cell adhesion The adhesion of one platelet to one or more other platelets via adhesion molecules. http://purl.obolibrary.org/obo/GO_0071214 cellular response to abiotic stimulus http://purl.obolibrary.org/obo/GO_0104004 cellular response to environmental stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. http://purl.obolibrary.org/obo/GO_0071478 cellular response to radiation http://purl.obolibrary.org/obo/GO_0071214 cellular response to abiotic stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. http://purl.obolibrary.org/obo/GO_0071479 cellular response to ionizing radiation http://purl.obolibrary.org/obo/GO_0071478 cellular response to radiation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays. http://purl.obolibrary.org/obo/GO_0071480 cellular response to gamma radiation http://purl.obolibrary.org/obo/GO_0071479 cellular response to ionizing radiation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum. http://purl.obolibrary.org/obo/GO_0071481 cellular response to X-ray http://purl.obolibrary.org/obo/GO_0071479 cellular response to ionizing radiation Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz). http://purl.obolibrary.org/obo/GO_0071484 cellular response to light intensity http://purl.obolibrary.org/obo/GO_0071482 cellular response to light stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus. http://purl.obolibrary.org/obo/GO_0071485 cellular response to absence of light http://purl.obolibrary.org/obo/GO_0071484 cellular response to light intensity Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli. http://purl.obolibrary.org/obo/GO_0071486 cellular response to high light intensity http://purl.obolibrary.org/obo/GO_0071484 cellular response to light intensity Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus. http://purl.obolibrary.org/obo/GO_0071487 cellular response to low light intensity stimulus http://purl.obolibrary.org/obo/GO_0071484 cellular response to light intensity Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2. http://purl.obolibrary.org/obo/GO_0071488 cellular response to very low light intensity stimulus http://purl.obolibrary.org/obo/GO_0071484 cellular response to light intensity Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec. http://purl.obolibrary.org/obo/GO_0071492 cellular response to UV-A http://purl.obolibrary.org/obo/GO_0070141 response to UV-A Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm. http://purl.obolibrary.org/obo/GO_0071493 cellular response to UV-B http://purl.obolibrary.org/obo/GO_0010224 response to UV-B Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm. http://purl.obolibrary.org/obo/GO_0071494 cellular response to UV-C http://purl.obolibrary.org/obo/GO_0010225 response to UV-C Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm. http://purl.obolibrary.org/obo/GO_0071971 extracellular exosome assembly http://purl.obolibrary.org/obo/GO_0070925 organelle assembly The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm. http://purl.obolibrary.org/obo/GO_0072347 response to anesthetic http://purl.obolibrary.org/obo/GO_0042493 response to drug Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation. http://purl.obolibrary.org/obo/GO_0072375 medium-term memory http://purl.obolibrary.org/obo/GO_0007613 memory The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster). http://purl.obolibrary.org/obo/GO_0072505 divalent inorganic anion homeostasis http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis Any process involved in the maintenance of an internal steady state of divalent inorganic anions within an organism or cell. http://purl.obolibrary.org/obo/GO_0072506 trivalent inorganic anion homeostasis http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis Any process involved in the maintenance of an internal steady state of trivalent inorganic anions within an organism or cell. http://purl.obolibrary.org/obo/GO_0072718 response to cisplatin http://purl.obolibrary.org/obo/GO_0009636 response to toxic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus. http://purl.obolibrary.org/obo/GO_0072758 response to topoisomerase inhibitor http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus. http://purl.obolibrary.org/obo/GO_0075044 positive regulation by symbiont of host autophagy http://purl.obolibrary.org/obo/GO_0075071 modulation by symbiont of host autophagy Any process in which a symbiont organism increases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0075071 modulation by symbiont of host autophagy http://purl.obolibrary.org/obo/GO_0010506 regulation of autophagy Any process in which a symbiont organism modulates the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0097712 vesicle targeting, trans-Golgi to periciliary membrane compartment http://purl.obolibrary.org/obo/GO_0048199 vesicle targeting, to, from or within Golgi The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces. http://purl.obolibrary.org/obo/GO_0097734 extracellular exosome biogenesis http://purl.obolibrary.org/obo/GO_0140112 extracellular vesicle biogenesis The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis http://purl.obolibrary.org/obo/GO_0050801 ion homeostasis Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell. http://purl.obolibrary.org/obo/GO_1900120 regulation of receptor binding http://purl.obolibrary.org/obo/GO_0043393 regulation of protein binding Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor. http://purl.obolibrary.org/obo/GO_1900121 negative regulation of receptor binding http://purl.obolibrary.org/obo/GO_1900120 regulation of receptor binding Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor. http://purl.obolibrary.org/obo/GO_1900122 positive regulation of receptor binding http://purl.obolibrary.org/obo/GO_1900120 regulation of receptor binding Any process that activates or increases the frequency, rate or extent of a protein or other molecule binding to a receptor. http://purl.obolibrary.org/obo/GO_1901343 negative regulation of vasculature development http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development. http://purl.obolibrary.org/obo/GO_1901563 response to camptothecin http://purl.obolibrary.org/obo/GO_0097305 response to alcohol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus. http://purl.obolibrary.org/obo/GO_1902019 regulation of cilium-dependent cell motility http://purl.obolibrary.org/obo/GO_2000145 regulation of cell motility Any process that modulates the frequency, rate or extent of cilium-dependent cell motility. http://purl.obolibrary.org/obo/GO_1902093 positive regulation of flagellated sperm motility http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of flagellated sperm motility. http://purl.obolibrary.org/obo/GO_1902337 regulation of apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1904748 regulation of apoptotic process involved in development Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis. http://purl.obolibrary.org/obo/GO_1902338 negative regulation of apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1902337 regulation of apoptotic process involved in morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis. http://purl.obolibrary.org/obo/GO_1902339 positive regulation of apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1902337 regulation of apoptotic process involved in morphogenesis Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis. http://purl.obolibrary.org/obo/GO_1903561 extracellular vesicle http://purl.obolibrary.org/obo/GO_0031982 vesicle Any vesicle that is part of the extracellular region. http://purl.obolibrary.org/obo/GO_1905153 regulation of membrane invagination http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of membrane invagination. http://purl.obolibrary.org/obo/GO_1905154 negative regulation of membrane invagination http://purl.obolibrary.org/obo/GO_1905153 regulation of membrane invagination Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination. http://purl.obolibrary.org/obo/GO_1905155 positive regulation of membrane invagination http://purl.obolibrary.org/obo/GO_1905153 regulation of membrane invagination Any process that activates or increases the frequency, rate or extent of membrane invagination. http://purl.obolibrary.org/obo/GO_1905349 ciliary transition zone assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone. http://purl.obolibrary.org/obo/GO_1905516 positive regulation of fertilization http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of fertilization. http://purl.obolibrary.org/obo/GO_2000070 regulation of response to water deprivation http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of response to water deprivation. http://purl.obolibrary.org/obo/GO_0140096 catalytic activity, acting on a protein http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalytic activity that acts to modify a protein. http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity http://purl.obolibrary.org/obo/CARO_0030000 biological entity Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure http://purl.obolibrary.org/obo/CARO_0000006 material anatomical entity Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. http://purl.obolibrary.org/obo/CARO_0000006 material anatomical entity http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity An anatomical entity that has mass. http://purl.obolibrary.org/obo/CARO_0000007 immaterial anatomical entity http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity An anatomical entity that has no mass. http://purl.obolibrary.org/obo/CARO_0000008 anatomical line http://purl.obolibrary.org/obo/CARO_0000007 immaterial anatomical entity A one dimensional, immaterial anatomical entity. http://purl.obolibrary.org/obo/CARO_0000010 anatomical boundary http://purl.obolibrary.org/obo/CARO_0000007 immaterial anatomical entity A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures. http://purl.obolibrary.org/obo/GO_0110028 positive regulation of mitotic spindle organization http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of mitotic spindle organization. http://purl.obolibrary.org/obo/PLANA_0007552 nu neoblast http://purl.obolibrary.org/obo/PLANA_0000012 neural progenitor cell A population of piwi-2+, ston-2+, elav-2+, ptprd-9+ and msi-1+ progenitors that give rise to one or more neuronal (pc-2+, synapsin+) lineages. http://purl.obolibrary.org/obo/PLANA_0007559 ovary nerve plexus http://purl.obolibrary.org/obo/BFO_0000040 material entity Nerve plexus surrounding the ovary. http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0030031 cell projection assembly Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization http://purl.obolibrary.org/obo/GO_0031344 regulation of cell projection organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections. http://purl.obolibrary.org/obo/GO_0106014 regulation of inflammatory response to wounding http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response Any process that modulates the frequency, rate or extent of the inflammatory response to wounding. http://purl.obolibrary.org/obo/GO_0106015 negative regulation of inflammatory response to wounding http://purl.obolibrary.org/obo/GO_0106014 regulation of inflammatory response to wounding Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding. http://purl.obolibrary.org/obo/GO_0106016 positive regulation of inflammatory response to wounding http://purl.obolibrary.org/obo/GO_0106014 regulation of inflammatory response to wounding Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding. http://purl.obolibrary.org/obo/GO_0104004 cellular response to environmental stimulus http://purl.obolibrary.org/obo/GO_0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus. http://purl.obolibrary.org/obo/PLANA_0000134 longitudinal muscle progenitor cell http://purl.obolibrary.org/obo/PLANA_0000019 muscle progenitor cell piwi-1+, myoD+, snail-1+ progenitor neoblasts required for specification and creation of longitudinal muscle fibers. http://purl.obolibrary.org/obo/PLANA_0007555 pax3/7+ neural progenitor cell http://purl.obolibrary.org/obo/PLANA_0000012 neural progenitor cell piwi-1+, pax3/7+ progenitor neoblasts implicated in the production of DBH+ ventral midline neurons. http://purl.obolibrary.org/obo/PLANA_0007538 adhesion gland http://purl.obolibrary.org/obo/PLANA_0000113 tissue Groupings of specialized epithelial cells located along the dorsal ventral margin. Adhesion glands are comprised of three cell types, the viscid and releasing gland cells which penetrate through an epithelial anchor cell and terminate at the epidermal surface. http://purl.obolibrary.org/obo/GO_0140053 mitochondrial gene expression http://purl.obolibrary.org/obo/GO_0010467 gene expression The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/PLANA_0004511 oral-aboral axis of the embryo http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Axis that runs from the oral pole and to the aboral pole of the spherical embryo (Stage 3 through early Stage 6). The oral pole is centered around the embryonic pharynx; the aboral pole is located opposite the embryonic pharynx. http://purl.obolibrary.org/obo/PLANA_0004512 primitive ectoderm surface http://purl.obolibrary.org/obo/BSPO_0000005 anatomical surface The apical surface of the single layered primitive ectoderm that is in contact with the environment. http://purl.obolibrary.org/obo/PLANA_0004513 primtive gut cell surface http://purl.obolibrary.org/obo/BSPO_0000005 anatomical surface The surface of the primitive gut cells in contact with the embryonic wall. http://purl.obolibrary.org/obo/PLANA_0004514 embryonic gut cell surface http://purl.obolibrary.org/obo/BSPO_0000005 anatomical surface The surface of phagocytic embryonic gut cells in contact with ingested yolk cells. http://purl.obolibrary.org/obo/PLANA_0004516 embryonic pharynx lumen epithelial surface http://purl.obolibrary.org/obo/BSPO_0000005 anatomical surface The epithelial cell surface lining the embryonic pharynx lumen. http://purl.obolibrary.org/obo/PLANA_0004517 blastomere http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity An undifferentiated, cycling embryonic cell in Stage 1-5 embryos that expresses piwi-1, numerous adult asexual neoblast enriched genes, and early embryo enriched genes. Blastomeres give rise to temporary embryonic tissues during Stage 2, continue dividing asynchronously in the embryonic wall, and ultimately give rise to neoblasts and adult lineage progenitors beginning in Stage 5. http://purl.obolibrary.org/obo/PLANA_0004518 extraembryonic cell http://purl.obolibrary.org/obo/PLANA_0000119 terminally differentiated cell Post-mitotic, terminally differentiated cells which, give rise to temporary embryonic tissues. http://purl.obolibrary.org/obo/PLANA_0004519 embryonic pharynx neuron http://purl.obolibrary.org/obo/PLANA_0004518 extraembryonic cell A neuronal cell innervating the embryonic pharynx. Four neurons innervate the radial muscle fibers that ring the oral opening. http://purl.obolibrary.org/obo/PLANA_0004520 embryonic pharynx radial muscle cell http://purl.obolibrary.org/obo/PLANA_0004518 extraembryonic cell Differentiated radial muscle cell present in the embryonic pharynx. http://purl.obolibrary.org/obo/PLANA_0004521 embryonic pharynx epithelial cell http://purl.obolibrary.org/obo/PLANA_0004518 extraembryonic cell foxA1+ epithelial cell contained in the embryonic pharynx. http://purl.obolibrary.org/obo/PLANA_0004524 embryonic pharynx circular muscle cell http://purl.obolibrary.org/obo/PLANA_0004518 extraembryonic cell Differentiated muscle cell present in a circular muscle fiber of the embryonic pharynx. http://purl.obolibrary.org/obo/PLANA_0004527 copulatory region http://purl.obolibrary.org/obo/PLANA_0000102 anatomical region Portion of the sexual biotype body plan immediately posterior to the parapharyngeal region, and immediately anterior to the tail. Encompasses the copulatory apparatus. http://purl.obolibrary.org/obo/PLANA_0004528 pharynx epithelium http://purl.obolibrary.org/obo/PLANA_0002118 epithelium Epithelia associated with the pharynx organ. http://purl.obolibrary.org/obo/PLANA_0004529 integumental system http://purl.obolibrary.org/obo/PLANA_0000114 anatomical system Connected anatomical system that forms a barrier between an animal and its environment. In vertebrates, the integumental system consists of the epidermis, dermis plus associated glands and adnexa such as hair and scales. In invertebrates, the integumental system may include cuticle. http://purl.obolibrary.org/obo/PLANA_0004530 oviduct lumen http://purl.obolibrary.org/obo/PLANA_0002053 lumen Anatomical space enclosed by the oviduct epithelium. http://purl.obolibrary.org/obo/PLANA_0004531 sperm duct lumen http://purl.obolibrary.org/obo/PLANA_0002053 lumen Anatomical space enclosed by the sperm duct epithelium. http://purl.obolibrary.org/obo/PLANA_0004532 oviduct epithelium http://purl.obolibrary.org/obo/PLANA_0002023 ciliated epithelium Ciliated epithelium lining the oviduct. http://purl.obolibrary.org/obo/PLANA_0004533 sperm duct epithelium http://purl.obolibrary.org/obo/PLANA_0002023 ciliated epithelium Ciliated epithelium lining the sperm duct. http://purl.obolibrary.org/obo/PLANA_0004534 tuba lumen http://purl.obolibrary.org/obo/PLANA_0002053 lumen Anatomical space enclosed by tuba. Oocyte(s) are fertilized in the tuba lumen by sperm that traveled up the oviduct. http://purl.obolibrary.org/obo/PLANA_0007539 anchor cell http://purl.obolibrary.org/obo/BFO_0000040 material entity Specialized epithelial cell located along the dorsoventral margin that surrounds the viscid and releasing gland cells. http://purl.obolibrary.org/obo/PLANA_0007540 viscid gland cell http://purl.obolibrary.org/obo/BFO_0000040 material entity A specialized insunk epithelial cell that is part of the adhesion glands which is responsible for production and excretion of the viscid substance allowing adherence to a substrate. http://purl.obolibrary.org/obo/PLANA_0007541 releasing gland cell http://purl.obolibrary.org/obo/BFO_0000040 material entity Specialized insunk epithelial cell that is part of the adhesion gland which is responsible for production of releasing substance. http://purl.obolibrary.org/obo/GO_0120111 neuron projection cytoplasm http://purl.obolibrary.org/obo/GO_0032838 plasma membrane bounded cell projection cytoplasm All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection. http://purl.obolibrary.org/obo/GO_0106064 regulation of cobalamin metabolic process http://purl.obolibrary.org/obo/GO_1901401 regulation of tetrapyrrole metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. http://purl.obolibrary.org/obo/PLANA_0000115 distal tubule epithelial cell http://purl.obolibrary.org/obo/PLANA_0000015 non ciliated epithelial cell Nonciliated epithelial cells that assemble into protonephridial distal tubules. http://purl.obolibrary.org/obo/PATO_0040012 plug shaped http://purl.obolibrary.org/obo/PATO_0000052 shape A shape that is in the form of a plug, being tube-like and expanded on one end. http://purl.obolibrary.org/obo/GO_0110159 regulation of mitotic spindle formation (spindle phase one) http://purl.obolibrary.org/obo/GO_1901673 regulation of mitotic spindle assembly Any process that modulates the frequency, rate or extent of mitotic spindle formation (spindle phase one). http://purl.obolibrary.org/obo/GO_0110160 negative regulation of mitotic spindle formation (spindle phase one) http://purl.obolibrary.org/obo/GO_0110159 regulation of mitotic spindle formation (spindle phase one) Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle formation (spindle phase one). http://purl.obolibrary.org/obo/GO_0110161 positive regulation of mitotic spindle formation (spindle phase one) http://purl.obolibrary.org/obo/GO_0110159 regulation of mitotic spindle formation (spindle phase one) Any process that activates or increases the frequency, rate or extent of mitotic spindle formation (spindle phase one). http://purl.obolibrary.org/obo/PLANP_0000540 less tails http://purl.obolibrary.org/obo/PLANP_0000530 abnormal number of tails The presence of a reduced number of tail. http://purl.obolibrary.org/obo/PLANP_0000541 more eyes http://purl.obolibrary.org/obo/PLANP_0000518 abnormal number of eyes The presence of an increased number of eye. http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly. http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly. http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly. http://purl.obolibrary.org/obo/PLANA_0000027 Smed sexual biotype http://purl.obolibrary.org/obo/PLANA_0000021 biotype Strains of cross-fertilizing hemaphrodites that reproduce sexually and do not undergo fission. After mating, each parent lays an egg capsule containing one or more embryos. Sexual Smed are stable diploids. http://purl.obolibrary.org/obo/PLANA_0000013 visceral musculature http://purl.obolibrary.org/obo/PLANA_0000431 organ Musculature surrounding internal organs of the body. http://purl.obolibrary.org/obo/PLANA_0000015 non ciliated epithelial cell http://purl.obolibrary.org/obo/PLANA_0000100 epithelial cell An epithelial cell lacking cilia. http://purl.obolibrary.org/obo/PLANA_0000024 Smed asexual biotype http://purl.obolibrary.org/obo/PLANA_0000021 biotype Asexual animal strains that reproduce solely through fission followed by whole body regeneration. Asexual Smed are stable diploids that harbor a chromosome translocation, making them karyotypically distinct from sexual Smed. http://purl.obolibrary.org/obo/PLANA_0000130 circular muscle progenitor cell http://purl.obolibrary.org/obo/PLANA_0002095 somatic cell piwi-1+, nkx1-1+ progenitor neoblasts required for specification of circular muscle fibers. http://purl.obolibrary.org/obo/PLANA_0007544 cintillo+ sensory neuron http://purl.obolibrary.org/obo/BFO_0000040 material entity A subset of sensory neurons located along the dorsal head margin. http://purl.obolibrary.org/obo/PLANA_0007548 transverse commissure http://purl.obolibrary.org/obo/PLANA_0002025 commissure Axon tracts from ganglia that cross the midline, connecting the two ventral nerve cords. http://purl.obolibrary.org/obo/PLANA_0007551 klf+ sensory neuron progenitor cell http://purl.obolibrary.org/obo/PLANA_0000012 neural progenitor cell piwi-1+, klf+ progenitor neoblasts required for production of cintillo+ sensory neurons. http://purl.obolibrary.org/obo/PLANA_0007553 lateral nerve http://purl.obolibrary.org/obo/PLANA_0000113 tissue A nerve extending laterally from the ventral nerve cord that innervates the submuscular plexus. http://purl.obolibrary.org/obo/PLANA_0007557 testis nerve plexus http://purl.obolibrary.org/obo/BFO_0000040 material entity Nerve plexus surrounding the testis. http://purl.obolibrary.org/obo/PLANP_0000001 abnormal cytoplasmic vesicle part http://purl.obolibrary.org/obo/PLANP_0000146 abnormal cytoplasmic part Abnormality of cytoplasmic vesicle part. http://purl.obolibrary.org/obo/PLANP_0000002 abnormal medial-lateral axis http://purl.obolibrary.org/obo/PLANP_0000542 abnormal whole organism Abnormality of medial-lateral axis of the whole animal. http://purl.obolibrary.org/obo/PLANP_0000003 abnormal oviduct lumen http://purl.obolibrary.org/obo/PLANP_0000023 abnormal oviduct Abnormality of oviduct lumen. http://purl.obolibrary.org/obo/PLANP_0000004 abnormal Category 4 cell http://purl.obolibrary.org/obo/PLANP_0000211 abnormal non ciliated epithelial cell Abnormality of Category 4 cell. http://purl.obolibrary.org/obo/PLANP_0000006 abnormal zygote http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of zygote. http://purl.obolibrary.org/obo/PLANP_0000008 abnormal male primordial germ cell http://purl.obolibrary.org/obo/PLANP_0000283 abnormal stem cell Abnormality of male primordial germ cell. http://purl.obolibrary.org/obo/PLANP_0000009 abnormal yolk cell http://purl.obolibrary.org/obo/PLANP_0000268 abnormal terminally differentiated cell Abnormality of yolk cell. http://purl.obolibrary.org/obo/PLANP_0000010 abnormal fission plane http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of fission plane. http://purl.obolibrary.org/obo/PLANP_0000011 abnormal central nervous system neuron http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron Abnormality of central nervous system neuron. http://purl.obolibrary.org/obo/PLANP_0000012 abnormal pharynx musculature http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of pharynx musculature. http://purl.obolibrary.org/obo/PLANP_0000014 abnormal collecting duct http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of collecting duct. http://purl.obolibrary.org/obo/PLANP_0000015 abnormal nucleolus http://purl.obolibrary.org/obo/PLANP_0000170 abnormal nuclear part Abnormality of nucleolus. http://purl.obolibrary.org/obo/PLANP_0000016 abnormal outer longitudinal muscle cell http://purl.obolibrary.org/obo/PLANP_0000129 abnormal longitudinal muscle cell Abnormality of outer longitudinal muscle cell. http://purl.obolibrary.org/obo/PLANP_0000017 abnormal tail stripe http://purl.obolibrary.org/obo/PLANP_0000261 abnormal anatomical region Abnormality of tail stripe. http://purl.obolibrary.org/obo/PLANP_0000019 abnormal Smed sexual biotype http://purl.obolibrary.org/obo/PLANP_0000305 abnormal biotype Abnormality of Smed sexual biotype. http://purl.obolibrary.org/obo/PLANP_0000020 abnormal rough endoplasmic reticulum http://purl.obolibrary.org/obo/PLANP_0000313 abnormal endoplasmic reticulum Abnormality of rough endoplasmic reticulum. http://purl.obolibrary.org/obo/PLANP_0000021 abnormal renal system http://purl.obolibrary.org/obo/PLANP_0000202 abnormal anatomical system Abnormality of renal system. http://purl.obolibrary.org/obo/PLANP_0000022 abnormal brain commissure http://purl.obolibrary.org/obo/PLANP_0000149 abnormal cephalic ganglia Abnormality of brain commissure. http://purl.obolibrary.org/obo/PLANP_0000023 abnormal oviduct http://purl.obolibrary.org/obo/PLANP_0000638 abnormal reproductive organ Abnormality of oviduct. http://purl.obolibrary.org/obo/PLANP_0000027 abnormal primitive ectoderm surface http://purl.obolibrary.org/obo/PLANP_0000435 abnormal primitive ectoderm Abnormality of primitive ectoderm surface. http://purl.obolibrary.org/obo/PLANP_0000029 abnormal neoblast http://purl.obolibrary.org/obo/PLANP_0000304 abnormal progenitor cell Abnormality of neoblast. http://purl.obolibrary.org/obo/PLANP_0000032 abnormal reproductive system product http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of reproductive system product. http://purl.obolibrary.org/obo/PLANP_0000033 abnormal pharynx inner longitudinal muscle cell http://purl.obolibrary.org/obo/PLANP_0000212 abnormal pharynx longitudinal muscle cell Abnormality of pharynx inner longitudinal muscle cell. http://purl.obolibrary.org/obo/PLANP_0000036 abnormal tail http://purl.obolibrary.org/obo/PLANP_0000261 abnormal anatomical region Abnormality of tail. http://purl.obolibrary.org/obo/PLANP_0000038 abnormal prepharyngeal region http://purl.obolibrary.org/obo/PLANP_0000261 abnormal anatomical region Abnormality of prepharyngeal region. http://purl.obolibrary.org/obo/PLANP_0000039 abnormal extracellular organelle http://purl.obolibrary.org/obo/PLANP_0000306 abnormal organelle Abnormality of extracellular organelle. http://purl.obolibrary.org/obo/PLANP_0000041 abnormal distal tubule epithelial cell http://purl.obolibrary.org/obo/PLANP_0000314 abnormal distal tubule Abnormality of distal tubule epithelial cell. http://purl.obolibrary.org/obo/PLANP_0000042 abnormal proximal tubule http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of proximal tubule. http://purl.obolibrary.org/obo/PLANP_0000043 abnormal organ http://purl.obolibrary.org/obo/PLANP_0000410 abnormal multicellular anatomical structure Abnormality of organ. http://purl.obolibrary.org/obo/PLANP_0000044 abnormal pigment cup cell http://purl.obolibrary.org/obo/PLANP_0000375 abnormal optic cup Abnormality of pigment cup cell. http://purl.obolibrary.org/obo/PLANP_0000045 abnormal glial cell http://purl.obolibrary.org/obo/PLANP_0000355 abnormal neuropil Abnormality of glial cell. http://purl.obolibrary.org/obo/PLANP_0000046 abnormal eye http://purl.obolibrary.org/obo/PLANP_0000198 abnormal visual system Abnormality of eye. http://purl.obolibrary.org/obo/PLANP_0000047 abnormal goblet cell http://purl.obolibrary.org/obo/PLANP_0000331 abnormal secretory cell Abnormality of goblet cell. http://purl.obolibrary.org/obo/PLANP_0000048 abnormal gastrodermis surface http://purl.obolibrary.org/obo/PLANP_0000175 abnormal gut Abnormality of gastrodermis surface. http://purl.obolibrary.org/obo/PLANP_0000050 abnormal bipolar neuron http://purl.obolibrary.org/obo/PLANP_0000415 abnormal transverse commissure Abnormality of bipolar neuron. http://purl.obolibrary.org/obo/PLANP_0000051 abnormal definitive pharynx http://purl.obolibrary.org/obo/PLANP_0000285 abnormal digestive system Abnormality of pharynx. http://purl.obolibrary.org/obo/PLANP_0000052 abnormal ventral epidermis http://purl.obolibrary.org/obo/PLANP_0000427 abnormal epidermis Abnormality of ventral epidermis. http://purl.obolibrary.org/obo/PLANP_0000053 abnormal cintillo+ sensory neuron http://purl.obolibrary.org/obo/PLANP_0000416 abnormal sensory neuron Abnormality of cintillo+ sensory neuron. http://purl.obolibrary.org/obo/PLANP_0000054 abnormal pharynx lumen http://purl.obolibrary.org/obo/PLANP_0000051 abnormal definitive pharynx Abnormality of pharynx lumen. http://purl.obolibrary.org/obo/PLANP_0000056 abnormal sigma neoblast http://purl.obolibrary.org/obo/PLANP_0000029 abnormal neoblast Abnormality of sigma neoblast. http://purl.obolibrary.org/obo/PLANP_0000057 abnormal inner longitudinal muscle cell http://purl.obolibrary.org/obo/PLANP_0000129 abnormal longitudinal muscle cell Abnormality of inner longitudinal muscle cell. http://purl.obolibrary.org/obo/PLANP_0000058 abnormal pharynx epithelium http://purl.obolibrary.org/obo/PLANP_0000051 abnormal definitive pharynx Abnormality of pharynx epithelium. http://purl.obolibrary.org/obo/PLANP_0000059 abnormal extraembryonic cell http://purl.obolibrary.org/obo/PLANP_0000268 abnormal terminally differentiated cell Abnormality of extraembryonic cell. http://purl.obolibrary.org/obo/PLANP_0000060 abnormal head http://purl.obolibrary.org/obo/PLANP_0000261 abnormal anatomical region Abnormality of head. http://purl.obolibrary.org/obo/PLANP_0000065 abnormal copulatory apparatus http://purl.obolibrary.org/obo/PLANP_0000353 abnormal reproductive system Abnormality of copulatory apparatus. http://purl.obolibrary.org/obo/PLANP_0000067 abnormal intracellular non-membrane-bounded organelle http://purl.obolibrary.org/obo/PLANP_0000373 abnormal intracellular organelle Abnormality of intracellular non-membrane-bounded organelle. http://purl.obolibrary.org/obo/PLANP_0000069 abnormal Stage 1 http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of Stage 1. http://purl.obolibrary.org/obo/PLANP_0000070 abnormal autonomic neuron http://purl.obolibrary.org/obo/PLANP_0000088 abnormal peripheral nervous system neuron Abnormality of autonomic neuron. http://purl.obolibrary.org/obo/PLANP_0000071 abnormal basal surface of the epidermis http://purl.obolibrary.org/obo/PLANP_0000427 abnormal epidermis Abnormality of basal surface of the epidermis. http://purl.obolibrary.org/obo/PLANP_0000076 abnormal embryonic gut cell http://purl.obolibrary.org/obo/PLANP_0000059 abnormal extraembryonic cell Abnormality of embryonic gut cell. http://purl.obolibrary.org/obo/PLANP_0000078 abnormal rhabdite http://purl.obolibrary.org/obo/PLANP_0000248 abnormal epithelial cell component Abnormality of rhabdite. http://purl.obolibrary.org/obo/PLANP_0000079 abnormal protonephridia http://purl.obolibrary.org/obo/PLANP_0000043 abnormal organ Abnormality of protonephridia. http://purl.obolibrary.org/obo/PLANP_0000080 abnormal round spermatid http://purl.obolibrary.org/obo/PLANP_0000221 abnormal spermatid Abnormality of round spermatid. http://purl.obolibrary.org/obo/PLANP_0000082 abnormal basal lamina of epithelium http://purl.obolibrary.org/obo/PLANP_0000381 abnormal integumental system Abnormality of basal lamina of epithelium. http://purl.obolibrary.org/obo/PLANP_0000083 abnormal mechanoreceptor cell http://purl.obolibrary.org/obo/PLANP_0000416 abnormal sensory neuron Abnormality of mechanoreceptor cell. http://purl.obolibrary.org/obo/PLANP_0000084 abnormal Stage 6 http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of Stage 6. http://purl.obolibrary.org/obo/PLANP_0000085 abnormal pharynx outer nerve plexus http://purl.obolibrary.org/obo/PLANP_0000352 abnormal nerve plexus Abnormality of pharynx outer nerve plexus. http://purl.obolibrary.org/obo/PLANP_0000088 abnormal peripheral nervous system neuron http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron Abnormality of peripheral nervous system neuron. http://purl.obolibrary.org/obo/PLANP_0000090 abnormal embryonic digestive system http://purl.obolibrary.org/obo/PLANP_0000138 abnormal extraembryonic structure Abnormality of embryonic digestive system. http://purl.obolibrary.org/obo/PLANP_0000091 abnormal muscle cell http://purl.obolibrary.org/obo/PLANP_0000183 abnormal electrically responsive cell Abnormality of muscle cell. http://purl.obolibrary.org/obo/PLANP_0000092 abnormal dopaminergic neuron http://purl.obolibrary.org/obo/PLANP_0000309 abnormal neurosecretory neuron Abnormality of dopaminergic neuron. http://purl.obolibrary.org/obo/PLANP_0000093 abnormal aboral hemisphere http://purl.obolibrary.org/obo/PLANP_0000307 abnormal embryonic subdivision Abnormality of aboral hemisphere. http://purl.obolibrary.org/obo/PLANP_0000094 abnormal cell-cell adhesion http://purl.obolibrary.org/obo/PLANP_0000110 abnormal cell-cell contact zone Abnormality of cell-cell adhesion. http://purl.obolibrary.org/obo/PLANP_0000095 abnormal nuclear pore http://purl.obolibrary.org/obo/PLANP_0000170 abnormal nuclear part Abnormality of nuclear pore. http://purl.obolibrary.org/obo/PLANP_0000096 abnormal sensory cell http://purl.obolibrary.org/obo/PLANP_0000268 abnormal terminally differentiated cell Abnormality of sensory cell. http://purl.obolibrary.org/obo/PLANP_0000097 abnormal ribosome http://purl.obolibrary.org/obo/PLANP_0000067 abnormal intracellular non-membrane-bounded organelle Abnormality of ribosome. http://purl.obolibrary.org/obo/PLANP_0000099 abnormal gamma neoblast http://purl.obolibrary.org/obo/PLANP_0000285 abnormal digestive system Abnormality of gamma neoblast. http://purl.obolibrary.org/obo/PLANP_0000103 abnormal posterior pole http://purl.obolibrary.org/obo/PLANP_0000261 abnormal anatomical region Abnormality of posterior pole. http://purl.obolibrary.org/obo/PLANP_0000104 abnormal oocyte http://purl.obolibrary.org/obo/PLANP_0000437 abnormal female germ cell Abnormality of oocyte. http://purl.obolibrary.org/obo/PLANP_0000105 abnormal sperm duct epithelium http://purl.obolibrary.org/obo/PLANP_0000151 abnormal sperm duct Abnormality of sperm duct epithelium. http://purl.obolibrary.org/obo/PLANP_0000108 abnormal gamete http://purl.obolibrary.org/obo/PLANP_0000288 abnormal germ cell Abnormality of gamete. http://purl.obolibrary.org/obo/PLANP_0000109 abnormal embryonic pharynx http://purl.obolibrary.org/obo/PLANP_0000090 abnormal embryonic digestive system Abnormality of embryonic pharynx. http://purl.obolibrary.org/obo/PLANP_0000110 abnormal cell-cell contact zone http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of cell-cell contact zone. http://purl.obolibrary.org/obo/PLANP_0000111 abnormal releasing gland cell http://purl.obolibrary.org/obo/PLANP_0000291 abnormal acidophilic gland cell Abnormality of releasing gland cell. http://purl.obolibrary.org/obo/PLANP_0000112 abnormal testis somatic gonadal cell http://purl.obolibrary.org/obo/PLANP_0000280 abnormal testis Abnormality of testis somatic gonadal cell. http://purl.obolibrary.org/obo/PLANP_0000113 abnormal bursal canal http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of bursal canal. http://purl.obolibrary.org/obo/PLANP_0000114 abnormal lateral branch http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of lateral branch. http://purl.obolibrary.org/obo/PLANP_0000115 abnormal dorsal stripe http://purl.obolibrary.org/obo/PLANP_0000135 abnormal dorsal epidermis Abnormality of dorsal stripe. http://purl.obolibrary.org/obo/PLANP_0000116 abnormal embryonic structure http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of embryonic structure. http://purl.obolibrary.org/obo/PLANP_0000117 abnormal epidermal progenitor cell http://purl.obolibrary.org/obo/PLANP_0000304 abnormal progenitor cell Abnormality of epidermal progenitor cell. http://purl.obolibrary.org/obo/PLANP_0000119 abnormal chromatin http://purl.obolibrary.org/obo/PLANP_0000170 abnormal nuclear part Abnormality of chromatin. http://purl.obolibrary.org/obo/PLANP_0000121 abnormal Stage 4 http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of Stage 4. http://purl.obolibrary.org/obo/PLANP_0000122 abnormal anchor cell http://purl.obolibrary.org/obo/PLANP_0000291 abnormal acidophilic gland cell Abnormality of anchor cell. http://purl.obolibrary.org/obo/PLANP_0000124 abnormal klf+ sensory neuron progenitor cell http://purl.obolibrary.org/obo/PLANP_0000365 abnormal peripheral nervous system Abnormality of klf+ sensory neuron progenitor cell. http://purl.obolibrary.org/obo/PLANP_0000125 abnormal optic chiasm http://purl.obolibrary.org/obo/PLANP_0000258 abnormal neuron projection bundle Abnormality of optic chiasm. http://purl.obolibrary.org/obo/PLANP_0000126 abnormal primitive ectoderm cell http://purl.obolibrary.org/obo/PLANP_0000435 abnormal primitive ectoderm Abnormality of primitive ectoderm cell. http://purl.obolibrary.org/obo/PLANP_0000127 abnormal oviduct epithelial cell http://purl.obolibrary.org/obo/PLANP_0000279 abnormal oviduct epithelium Abnormality of oviduct epithelial cell. http://purl.obolibrary.org/obo/PLANP_0000128 abnormal male germ cell http://purl.obolibrary.org/obo/PLANP_0000288 abnormal germ cell Abnormality of male germ cell. http://purl.obolibrary.org/obo/PLANP_0000129 abnormal longitudinal muscle cell http://purl.obolibrary.org/obo/PLANP_0000392 abnormal body wall musculature Abnormality of longitudinal muscle cell. http://purl.obolibrary.org/obo/PLANP_0000130 abnormal oral opening http://purl.obolibrary.org/obo/PLANP_0000439 abnormal mouth Abnormality of oral opening. http://purl.obolibrary.org/obo/PLANP_0000131 abnormal membrane-bounded organelle http://purl.obolibrary.org/obo/PLANP_0000306 abnormal organelle Abnormality of membrane-bounded organelle. http://purl.obolibrary.org/obo/PLANP_0000132 abnormal spermatogonium http://purl.obolibrary.org/obo/PLANP_0000304 abnormal progenitor cell Abnormality of spermatogonium. http://purl.obolibrary.org/obo/PLANP_0000135 abnormal dorsal epidermis http://purl.obolibrary.org/obo/PLANP_0000052 abnormal ventral epidermis Abnormality of dorsal region of the epidermis. http://purl.obolibrary.org/obo/PLANP_0000136 abnormal seminal vesicle http://purl.obolibrary.org/obo/PLANP_0000065 abnormal copulatory apparatus Abnormality of seminal vesicle. http://purl.obolibrary.org/obo/PLANP_0000138 abnormal extraembryonic structure http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of extraembryonic structure. http://purl.obolibrary.org/obo/PLANP_0000139 abnormal Stage 3 http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of Stage 3. http://purl.obolibrary.org/obo/PLANP_0000140 abnormal adhesion gland http://purl.obolibrary.org/obo/PLANP_0000384 abnormal secretory system Abnormality of adhesion gland. http://purl.obolibrary.org/obo/PLANP_0000143 abnormal neural progenitor http://purl.obolibrary.org/obo/PLANP_0000304 abnormal progenitor cell Abnormality of neural progenitor cell. http://purl.obolibrary.org/obo/PLANP_0000144 abnormal yolk syncytium http://purl.obolibrary.org/obo/PLANP_0000681 abnormal syncytium Abnormality of yolk syncytium. http://purl.obolibrary.org/obo/PLANP_0000145 abnormal plasma membrane http://purl.obolibrary.org/obo/PLANP_0000229 abnormal membrane Abnormality of plasma membrane. http://purl.obolibrary.org/obo/PLANP_0000146 abnormal cytoplasmic part http://purl.obolibrary.org/obo/PLANP_0000358 abnormal intracellular part Abnormality of cytoplasmic part. http://purl.obolibrary.org/obo/PLANP_0000147 abnormal unipolar neuron http://purl.obolibrary.org/obo/PLANP_0000416 abnormal sensory neuron Abnormality of unipolar neuron. http://purl.obolibrary.org/obo/PLANP_0000149 abnormal cephalic ganglia http://purl.obolibrary.org/obo/PLANP_0000238 abnormal central nervous system Abnormality of cephalic ganglia. http://purl.obolibrary.org/obo/PLANP_0000150 abnormal ciliated epithelial cell http://purl.obolibrary.org/obo/PLANP_0000310 abnormal epithelial cell Abnormality of ciliated epithelial cell. http://purl.obolibrary.org/obo/PLANP_0000151 abnormal sperm duct http://purl.obolibrary.org/obo/PLANP_0000638 abnormal reproductive organ Abnormality of sperm duct. http://purl.obolibrary.org/obo/PLANP_0000152 abnormal anterior pole progenitor cell http://purl.obolibrary.org/obo/PLANP_0000029 abnormal neoblast Abnormality of anterior pole progenitor cell. http://purl.obolibrary.org/obo/PLANP_0000153 abnormal anterior-posterior axis http://purl.obolibrary.org/obo/PLANP_0000542 abnormal whole organism Abnormality of anterior-posterior axis of the whole animal. http://purl.obolibrary.org/obo/PLANP_0000154 abnormal plasma membrane part http://purl.obolibrary.org/obo/PLANP_0000388 abnormal membrane part Abnormality of plasma membrane part. http://purl.obolibrary.org/obo/PLANP_0000155 abnormal embryonic pharynx circular muscle cell http://purl.obolibrary.org/obo/PLANP_0000109 abnormal embryonic pharynx Abnormality of embryonic pharynx circular muscle cell. http://purl.obolibrary.org/obo/PLANP_0000156 abnormal submuscular nerve plexus http://purl.obolibrary.org/obo/PLANP_0000352 abnormal nerve plexus Abnormality of submuscular nerve plexus. http://purl.obolibrary.org/obo/PLANP_0000158 abnormal female primordial germ cell http://purl.obolibrary.org/obo/PLANP_0000437 abnormal female germ cell Abnormality of female primordial germ cell. http://purl.obolibrary.org/obo/PLANP_0000159 abnormal photoreceptor neuron http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron Abnormality of photoreceptor neuron. http://purl.obolibrary.org/obo/PLANP_0000160 abnormal asexual adult http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of asexual adult. http://purl.obolibrary.org/obo/PLANP_0000161 abnormal gonad http://purl.obolibrary.org/obo/PLANP_0000638 abnormal reproductive organ Abnormality of gonad. http://purl.obolibrary.org/obo/PLANP_0000164 abnormal ventral nerve cord http://purl.obolibrary.org/obo/PLANP_0000238 abnormal central nervous system Abnormality of ventral nerve cord. http://purl.obolibrary.org/obo/PLANP_0000165 abnormal embryonic wall http://purl.obolibrary.org/obo/PLANP_0000307 abnormal embryonic subdivision Abnormality of embryonic wall. http://purl.obolibrary.org/obo/PLANP_0000166 abnormal testis nerve plexus http://purl.obolibrary.org/obo/PLANP_0000353 abnormal reproductive system Abnormality of testis nerve plexus. http://purl.obolibrary.org/obo/PLANP_0000167 abnormal pharynx radial muscle cell http://purl.obolibrary.org/obo/PLANP_0000091 abnormal muscle cell Abnormality of pharynx radial muscle cell. http://purl.obolibrary.org/obo/PLANP_0000169 abnormal clonogenic neoblast http://purl.obolibrary.org/obo/PLANP_0000029 abnormal neoblast Abnormality of clonogenic neoblast. http://purl.obolibrary.org/obo/PLANP_0000170 abnormal nuclear part http://purl.obolibrary.org/obo/PLANP_0000200 abnormal nucleus Abnormality of nuclear part. http://purl.obolibrary.org/obo/PLANP_0000173 abnormal sensory system http://purl.obolibrary.org/obo/PLANP_0000202 abnormal anatomical system Abnormality of sensory system. http://purl.obolibrary.org/obo/PLANP_0000175 abnormal gut http://purl.obolibrary.org/obo/PLANP_0000285 abnormal digestive system Abnormality of gut. http://purl.obolibrary.org/obo/PLANP_0000177 abnormal dorsal ventral margin http://purl.obolibrary.org/obo/PLANP_0000542 abnormal whole organism Abnormality of dorsal ventral margin of the whole animal. http://purl.obolibrary.org/obo/PLANP_0000179 abnormal ovary http://purl.obolibrary.org/obo/PLANP_0000161 abnormal gonad Abnormality of ovary. http://purl.obolibrary.org/obo/PLANP_0000181 abnormal GABAergic neuron http://purl.obolibrary.org/obo/PLANP_0000309 abnormal neurosecretory neuron Abnormality of GABAergic neuron. http://purl.obolibrary.org/obo/PLANP_0000183 abnormal electrically responsive cell http://purl.obolibrary.org/obo/PLANP_0000268 abnormal terminally differentiated cell Abnormality of electrically responsive cell. http://purl.obolibrary.org/obo/PLANP_0000185 abnormal pharynx pouch http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of pharynx pouch. http://purl.obolibrary.org/obo/PLANP_0000186 abnormal musculature system http://purl.obolibrary.org/obo/PLANP_0000202 abnormal anatomical system Abnormality of musculature system. http://purl.obolibrary.org/obo/PLANP_0000187 abnormal actin-based cell projection http://purl.obolibrary.org/obo/PLANP_0000366 abnormal cell projection Abnormality of actin-based cell projection. http://purl.obolibrary.org/obo/PLANP_0000188 abnormal efferent neuron http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron Abnormality of efferent neuron. http://purl.obolibrary.org/obo/PLANP_0000191 abnormal embryonic pharynx lumen http://purl.obolibrary.org/obo/PLANP_0000109 abnormal embryonic pharynx Abnormality of embryonic pharynx lumen. http://purl.obolibrary.org/obo/PLANP_0000192 abnormal non-membrane-bounded organelle http://purl.obolibrary.org/obo/PLANP_0000306 abnormal organelle Abnormality of non-membrane-bounded organelle. http://purl.obolibrary.org/obo/PLANP_0000193 abnormal parapharyngeal region http://purl.obolibrary.org/obo/PLANP_0000261 abnormal anatomical region Abnormality of parapharyngeal region. http://purl.obolibrary.org/obo/PLANP_0000194 abnormal oral hemisphere http://purl.obolibrary.org/obo/PLANP_0000307 abnormal embryonic subdivision Abnormality of oral hemisphere. http://purl.obolibrary.org/obo/PLANP_0000196 abnormal electrically signaling cell http://purl.obolibrary.org/obo/PLANP_0000268 abnormal terminally differentiated cell Abnormality of electrically signaling cell. http://purl.obolibrary.org/obo/PLANP_0000198 abnormal visual system http://purl.obolibrary.org/obo/PLANP_0000202 abnormal anatomical system Abnormality of visual system. http://purl.obolibrary.org/obo/PLANP_0000199 abnormal nervous system http://purl.obolibrary.org/obo/PLANP_0000202 abnormal anatomical system Abnormality of nervous system. http://purl.obolibrary.org/obo/PLANP_0000200 abnormal nucleus http://purl.obolibrary.org/obo/PLANP_0000398 abnormal intracellular membrane-bounded organelle Abnormality of nucleus. http://purl.obolibrary.org/obo/PLANP_0000202 abnormal anatomical system http://purl.obolibrary.org/obo/PLANP_0000410 abnormal multicellular anatomical structure Abnormality of anatomical system. http://purl.obolibrary.org/obo/PLANP_0000205 abnormal gland cell http://purl.obolibrary.org/obo/PLANP_0000310 abnormal epithelial cell Abnormality of gland cell. http://purl.obolibrary.org/obo/PLANP_0000206 abnormal bounding membrane of organelle http://purl.obolibrary.org/obo/PLANP_0000229 abnormal membrane Abnormality of bounding membrane of organelle. http://purl.obolibrary.org/obo/PLANP_0000207 abnormal Category 3 cell http://purl.obolibrary.org/obo/PLANP_0000381 abnormal integumental system Abnormality of Category 3 cell. http://purl.obolibrary.org/obo/PLANP_0000209 abnormal gastrodermis http://purl.obolibrary.org/obo/PLANP_0000175 abnormal gut Abnormality of gastrodermis. http://purl.obolibrary.org/obo/PLANP_0000211 abnormal non ciliated epithelial cell http://purl.obolibrary.org/obo/PLANP_0000310 abnormal epithelial cell Abnormality of non ciliated epithelial cell. http://purl.obolibrary.org/obo/PLANP_0000212 abnormal pharynx longitudinal muscle cell http://purl.obolibrary.org/obo/PLANP_0000091 abnormal muscle cell Abnormality of pharynx longitudinal muscle cell. http://purl.obolibrary.org/obo/PLANP_0000213 abnormal left-right axis http://purl.obolibrary.org/obo/PLANP_0000542 abnormal whole organism Abnormality of left-right axis of the whole animal. http://purl.obolibrary.org/obo/PLANP_0000214 abnormal trail cell http://purl.obolibrary.org/obo/PLANP_0000198 abnormal visual system Abnormality of trail cell. http://purl.obolibrary.org/obo/PLANP_0000215 abnormal blastomere http://purl.obolibrary.org/obo/PLANP_0000425 abnormal ectolecithal embryo Abnormality of blastomere. http://purl.obolibrary.org/obo/PLANP_0000216 abnormal oogonial cell http://purl.obolibrary.org/obo/PLANP_0000437 abnormal female germ cell Abnormality of oogonial cell. http://purl.obolibrary.org/obo/PLANP_0000218 abnormal Stage 8 http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of Stage 8. http://purl.obolibrary.org/obo/PLANP_0000219 abnormal copulatory region http://purl.obolibrary.org/obo/PLANP_0000261 abnormal anatomical region Abnormality of copulatory region. http://purl.obolibrary.org/obo/PLANP_0000220 abnormal Golgi apparatus http://purl.obolibrary.org/obo/PLANP_0000398 abnormal intracellular membrane-bounded organelle Abnormality of Golgi apparatus. http://purl.obolibrary.org/obo/PLANP_0000221 abnormal spermatid http://purl.obolibrary.org/obo/PLANP_0000280 abnormal testis Abnormality of spermatid. http://purl.obolibrary.org/obo/PLANP_0000222 abnormal definitive organism subdivision http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of definitive organism subdivision. http://purl.obolibrary.org/obo/PLANP_0000226 abnormal vitelline gland http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of vitelline gland. http://purl.obolibrary.org/obo/PLANP_0000228 abnormal embryonic pharynx neuron http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron Abnormality of embryonic pharynx neuron. http://purl.obolibrary.org/obo/PLANP_0000229 abnormal membrane http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of membrane. http://purl.obolibrary.org/obo/PLANP_0000230 abnormal flame cell http://purl.obolibrary.org/obo/PLANP_0000406 abnormal flame bulb Abnormality of flame cell. http://purl.obolibrary.org/obo/PLANP_0000232 abnormal cytoplasm http://purl.obolibrary.org/obo/PLANP_0000358 abnormal intracellular part Abnormality of cytoplasm. http://purl.obolibrary.org/obo/PLANP_0000233 abnormal oral-aboral axis http://purl.obolibrary.org/obo/PLANP_0000289 abnormal embryo Abnormality of oral-aboral axis of the embryo. http://purl.obolibrary.org/obo/PLANP_0000234 abnormal zeta neoblast http://purl.obolibrary.org/obo/PLANP_0000381 abnormal integumental system Abnormality of zeta neoblast. http://purl.obolibrary.org/obo/PLANP_0000237 abnormal juvenile http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of juvenile. http://purl.obolibrary.org/obo/PLANP_0000238 abnormal central nervous system http://purl.obolibrary.org/obo/PLANP_0000199 abnormal nervous system Abnormality of central nervous system. http://purl.obolibrary.org/obo/PLANP_0000239 abnormal pharynx inner circular muscle cell http://purl.obolibrary.org/obo/PLANP_0000376 abnormal pharynx circular muscle cell Abnormality of pharynx inner circular muscle cell. http://purl.obolibrary.org/obo/PLANP_0000242 abnormal motor neuron http://purl.obolibrary.org/obo/PLANP_0000188 abnormal efferent neuron Abnormality of motor neuron. http://purl.obolibrary.org/obo/PLANP_0000243 abnormal apical surface of the epidermis http://purl.obolibrary.org/obo/PLANP_0000427 abnormal epidermis Abnormality of apical surface of the epidermis. http://purl.obolibrary.org/obo/PLANP_0000245 abnormal tuba http://purl.obolibrary.org/obo/PLANP_0000638 abnormal reproductive organ Abnormality of tuba. http://purl.obolibrary.org/obo/PLANP_0000246 abnormal posterior primary gut branch http://purl.obolibrary.org/obo/PLANP_0000635 abnormal primary gut branch Abnormality of posterior primary gut branch. http://purl.obolibrary.org/obo/PLANP_0000248 abnormal epithelial cell component http://purl.obolibrary.org/obo/PLANP_0000310 abnormal epithelial cell Abnormality of epithelial cell component. http://purl.obolibrary.org/obo/PLANP_0000250 abnormal spermatogonial stem cell http://purl.obolibrary.org/obo/PLANP_0000283 abnormal stem cell Abnormality of spermatogonial stem cell. http://purl.obolibrary.org/obo/PLANP_0000251 abnormal ovary nerve plexus http://purl.obolibrary.org/obo/PLANP_0000353 abnormal reproductive system Abnormality of ovary nerve plexus. http://purl.obolibrary.org/obo/PLANP_0000252 abnormal midline http://purl.obolibrary.org/obo/PLANP_0000261 abnormal anatomical region Abnormality of midline. http://purl.obolibrary.org/obo/PLANP_0000254 abnormal pharynx inner nerve plexus http://purl.obolibrary.org/obo/PLANP_0000352 abnormal nerve plexus Abnormality of pharynx inner nerve plexus. http://purl.obolibrary.org/obo/PLANP_0000256 abnormal parenchymal musculature http://purl.obolibrary.org/obo/PLANP_0000186 abnormal musculature system Abnormality of parenchymal musculature. http://purl.obolibrary.org/obo/PLANP_0000258 abnormal neuron projection bundle http://purl.obolibrary.org/obo/PLANP_0000365 abnormal peripheral nervous system Abnormality of neuron projection bundle. http://purl.obolibrary.org/obo/PLANP_0000261 abnormal anatomical region http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of anatomical region. http://purl.obolibrary.org/obo/PLANP_0000264 abnormal Category 2 cell http://purl.obolibrary.org/obo/PLANP_0000381 abnormal integumental system Abnormality of Category 2 cell. http://purl.obolibrary.org/obo/PLANP_0000265 abnormal cell-cell junction http://purl.obolibrary.org/obo/PLANP_0000420 abnormal cell junction Abnormality of cell-cell junction. http://purl.obolibrary.org/obo/PLANP_0000266 abnormal TrpA+ central nervous system neuron http://purl.obolibrary.org/obo/PLANP_0000149 abnormal cephalic ganglia Abnormality of TrpA+ central nervous system neuron. http://purl.obolibrary.org/obo/PLANP_0000267 abnormal smooth endoplasmic reticulum http://purl.obolibrary.org/obo/PLANP_0000313 abnormal endoplasmic reticulum Abnormality of smooth endoplasmic reticulum. http://purl.obolibrary.org/obo/PLANP_0000268 abnormal terminally differentiated cell http://purl.obolibrary.org/obo/PLANP_0000644 abnormal somatic cell Abnormality of terminally differentiated cell. http://purl.obolibrary.org/obo/PLANP_0000269 abnormal basophilic gland cell http://purl.obolibrary.org/obo/PLANP_0000205 abnormal gland cell Abnormality of basophilic gland cell. http://purl.obolibrary.org/obo/PLANP_0000270 abnormal primordium http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of primordium. http://purl.obolibrary.org/obo/PLANP_0000271 abnormal euchromatin http://purl.obolibrary.org/obo/PLANP_0000119 abnormal chromatin Abnormality of euchromatin. http://purl.obolibrary.org/obo/PLANP_0000275 abnormal proximal tubule epithelial cell http://purl.obolibrary.org/obo/PLANP_0000150 abnormal ciliated epithelial cell Abnormality of proximal tubule epithelial cell. http://purl.obolibrary.org/obo/PLANP_0000277 abnormal anterior pole http://purl.obolibrary.org/obo/PLANP_0000261 abnormal anatomical region Abnormality of anterior pole. http://purl.obolibrary.org/obo/PLANP_0000279 abnormal oviduct epithelium http://purl.obolibrary.org/obo/PLANP_0000023 abnormal oviduct Abnormality of oviduct epithelium. http://purl.obolibrary.org/obo/PLANP_0000280 abnormal testis http://purl.obolibrary.org/obo/PLANP_0000161 abnormal gonad Abnormality of testis. http://purl.obolibrary.org/obo/PLANP_0000281 abnormal Category 5 cell http://purl.obolibrary.org/obo/PLANP_0000150 abnormal ciliated epithelial cell Abnormality of Category 5 cell. http://purl.obolibrary.org/obo/PLANP_0000283 abnormal stem cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of stem cell. http://purl.obolibrary.org/obo/PLANP_0000285 abnormal digestive system http://purl.obolibrary.org/obo/PLANP_0000202 abnormal anatomical system Abnormality of digestive system. http://purl.obolibrary.org/obo/PLANP_0000287 abnormal viscid gland cell http://purl.obolibrary.org/obo/PLANP_0000291 abnormal acidophilic gland cell Abnormality of viscid gland cell. http://purl.obolibrary.org/obo/PLANP_0000288 abnormal germ cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of germ cell. http://purl.obolibrary.org/obo/PLANP_0000289 abnormal embryo http://purl.obolibrary.org/obo/PLANP_0000032 abnormal reproductive system product Abnormality of embryo. http://purl.obolibrary.org/obo/PLANP_0000290 abnormal anterior commissure http://purl.obolibrary.org/obo/PLANP_0000022 abnormal brain commissure Abnormality of anterior commissure. http://purl.obolibrary.org/obo/PLANP_0000291 abnormal acidophilic gland cell http://purl.obolibrary.org/obo/PLANP_0000205 abnormal gland cell Abnormality of acidophilic gland cell. http://purl.obolibrary.org/obo/PLANP_0000293 abnormal tuba lumen http://purl.obolibrary.org/obo/PLANP_0000245 abnormal tuba Abnormality of tuba lumen. http://purl.obolibrary.org/obo/PLANP_0000294 abnormal Stage 5 http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of Stage 5. http://purl.obolibrary.org/obo/PLANP_0000295 abnormal embryonic gut cavity http://purl.obolibrary.org/obo/PLANP_0000581 abnormal embryonic gut Abnormality of embryonic gut cavity. http://purl.obolibrary.org/obo/PLANP_0000296 abnormal pharynx pouch epithelial surface http://purl.obolibrary.org/obo/PLANP_0000685 abnormal pharynx pouch epithelium Abnormality of pharynx pouch epithelial surface. http://purl.obolibrary.org/obo/PLANP_0000297 abnormal embryonic gut cell surface http://purl.obolibrary.org/obo/PLANP_0000076 abnormal embryonic gut cell Abnormality of embryonic gut cell surface. http://purl.obolibrary.org/obo/PLANP_0000298 abnormal vacuole http://purl.obolibrary.org/obo/PLANP_0000131 abnormal membrane-bounded organelle Abnormality of vacuole. http://purl.obolibrary.org/obo/PLANP_0000299 abnormal proximal-distal axis http://purl.obolibrary.org/obo/PLANP_0000542 abnormal whole organism Abnormality of proximal-distal axis of the whole animal. http://purl.obolibrary.org/obo/PLANP_0000301 abnormal sperm duct lumen http://purl.obolibrary.org/obo/PLANP_0000151 abnormal sperm duct Abnormality of sperm duct lumen. http://purl.obolibrary.org/obo/PLANP_0000302 abnormal neuron associated cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/PLANP_0000268 abnormal terminally differentiated cell Abnormality of neuron associated cell (sensu Nematoda and Protostomia). http://purl.obolibrary.org/obo/PLANP_0000304 abnormal progenitor cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of progenitor cell. http://purl.obolibrary.org/obo/PLANP_0000305 abnormal biotype http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of biotype. http://purl.obolibrary.org/obo/PLANP_0000306 abnormal organelle http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of organelle. http://purl.obolibrary.org/obo/PLANP_0000307 abnormal embryonic subdivision http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of embryonic subdivision. http://purl.obolibrary.org/obo/PLANP_0000309 abnormal neurosecretory neuron http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron Abnormality of neurosecretory neuron. http://purl.obolibrary.org/obo/PLANP_0000310 abnormal epithelial cell http://purl.obolibrary.org/obo/PLANP_0000268 abnormal terminally differentiated cell Abnormality of epithelial cell. http://purl.obolibrary.org/obo/PLANP_0000311 abnormal serotonergic neuron http://purl.obolibrary.org/obo/PLANP_0000309 abnormal neurosecretory neuron Abnormality of serotonergic neuron. http://purl.obolibrary.org/obo/PLANP_0000312 abnormal muscle progenitor http://purl.obolibrary.org/obo/PLANP_0000304 abnormal progenitor cell Abnormality of muscle progenitor cell. http://purl.obolibrary.org/obo/PLANP_0000313 abnormal endoplasmic reticulum http://purl.obolibrary.org/obo/PLANP_0000398 abnormal intracellular membrane-bounded organelle Abnormality of endoplasmic reticulum. http://purl.obolibrary.org/obo/PLANP_0000314 abnormal distal tubule http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of distal tubule. http://purl.obolibrary.org/obo/PLANP_0000315 abnormal copulatory bursa http://purl.obolibrary.org/obo/PLANP_0000065 abnormal copulatory apparatus Abnormality of copulatory bursa. http://purl.obolibrary.org/obo/PLANP_0000317 abnormal esophagus http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of esophagus. http://purl.obolibrary.org/obo/PLANP_0000318 abnormal secondary gut branch http://purl.obolibrary.org/obo/PLANP_0000666 abnormal gut branch Abnormality of secondary gut branch. http://purl.obolibrary.org/obo/PLANP_0000320 abnormal Stage 2 http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of Stage 2. http://purl.obolibrary.org/obo/PLANP_0000322 abnormal protonephridial progenitor http://purl.obolibrary.org/obo/PLANP_0000304 abnormal progenitor cell Abnormality of protonephridial progenitor cell. http://purl.obolibrary.org/obo/PLANP_0000323 abnormal ventral midline http://purl.obolibrary.org/obo/PLANP_0000252 abnormal midline Abnormality of ventral midline. http://purl.obolibrary.org/obo/PLANP_0000327 abnormal primtive gut cell surface http://purl.obolibrary.org/obo/PLANP_0000421 abnormal primitive gut cell Abnormality of primtive gut cell surface. http://purl.obolibrary.org/obo/PLANP_0000329 abnormal egg capsule http://purl.obolibrary.org/obo/PLANP_0000032 abnormal reproductive system product Abnormality of egg capsule. http://purl.obolibrary.org/obo/PLANP_0000330 abnormal multipolar neuron http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron Abnormality of multipolar neuron. http://purl.obolibrary.org/obo/PLANP_0000331 abnormal secretory cell http://purl.obolibrary.org/obo/PLANP_0000268 abnormal terminally differentiated cell Abnormality of secretory cell. http://purl.obolibrary.org/obo/PLANP_0000332 abnormal pharynx outer longitudinal muscle cell http://purl.obolibrary.org/obo/PLANP_0000212 abnormal pharynx longitudinal muscle cell Abnormality of pharynx outer longitudinal muscle cell. http://purl.obolibrary.org/obo/PLANP_0000333 abnormal penis papilla http://purl.obolibrary.org/obo/PLANP_0000065 abnormal copulatory apparatus Abnormality of penis papilla. http://purl.obolibrary.org/obo/PLANP_0000334 abnormal TrpA+ neural progenitor cell http://purl.obolibrary.org/obo/PLANP_0000365 abnormal peripheral nervous system Abnormality of TrpA+ neural progenitor cell. http://purl.obolibrary.org/obo/PLANP_0000335 abnormal interneuron http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron Abnormality of interneuron. http://purl.obolibrary.org/obo/PLANP_0000336 abnormal subepidermal nerve plexus http://purl.obolibrary.org/obo/PLANP_0000381 abnormal integumental system Abnormality of subepidermal nerve plexus. http://purl.obolibrary.org/obo/PLANP_0000338 abnormal longitudinal muscle progenitor cell http://purl.obolibrary.org/obo/PLANP_0000312 abnormal muscle progenitor Abnormality of longitudinal muscle progenitor cell. http://purl.obolibrary.org/obo/PLANP_0000339 abnormal microvillus http://purl.obolibrary.org/obo/PLANP_0000187 abnormal actin-based cell projection Abnormality of microvillus. http://purl.obolibrary.org/obo/PLANP_0000340 abnormal adult hermaphrodite http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of adult hermaphrodite. http://purl.obolibrary.org/obo/PLANP_0000341 abnormal mitochondrion http://purl.obolibrary.org/obo/PLANP_0000398 abnormal intracellular membrane-bounded organelle Abnormality of mitochondrion. http://purl.obolibrary.org/obo/PLANP_0000342 abnormal enteric musculature http://purl.obolibrary.org/obo/PLANP_0000409 abnormal visceral musculature Abnormality of enteric musculature. http://purl.obolibrary.org/obo/PLANP_0000345 abnormal dorsal midline http://purl.obolibrary.org/obo/PLANP_0000323 abnormal ventral midline Abnormality of dorsal midline. http://purl.obolibrary.org/obo/PLANP_0000346 abnormal ganglion http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of ganglion. http://purl.obolibrary.org/obo/PLANP_0000348 abnormal pharynx lumen epithelial surface http://purl.obolibrary.org/obo/PLANP_0000396 abnormal pharynx inner epithelium Abnormality of pharynx inner epithelium surface. http://purl.obolibrary.org/obo/PLANP_0000349 abnormal sperm http://purl.obolibrary.org/obo/PLANP_0000280 abnormal testis Abnormality of sperm. http://purl.obolibrary.org/obo/PLANP_0000350 abnormal serotonergic neural progenitor cell http://purl.obolibrary.org/obo/PLANP_0000365 abnormal peripheral nervous system Abnormality of serotonergic neural progenitor cell. http://purl.obolibrary.org/obo/PLANP_0000352 abnormal nerve plexus http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of nerve plexus. http://purl.obolibrary.org/obo/PLANP_0000353 abnormal reproductive system http://purl.obolibrary.org/obo/PLANP_0000202 abnormal anatomical system Abnormality of reproductive system. http://purl.obolibrary.org/obo/PLANP_0000354 abnormal afferent neuron http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron Abnormality of afferent neuron. http://purl.obolibrary.org/obo/PLANP_0000355 abnormal neuropil http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of neuropil. http://purl.obolibrary.org/obo/PLANP_0000356 abnormal intestinal phagocyte http://purl.obolibrary.org/obo/PLANP_0000268 abnormal terminally differentiated cell Abnormality of intestinal phagocyte. http://purl.obolibrary.org/obo/PLANP_0000357 abnormal anterior primary gut branch http://purl.obolibrary.org/obo/PLANP_0000635 abnormal primary gut branch Abnormality of anterior primary gut branch. http://purl.obolibrary.org/obo/PLANP_0000358 abnormal intracellular part http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of intracellular part. http://purl.obolibrary.org/obo/PLANP_0000360 abnormal digestive tract lumen http://purl.obolibrary.org/obo/PLANP_0000175 abnormal gut Abnormality of digestive tract lumen. http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of cell. http://purl.obolibrary.org/obo/PLANP_0000364 abnormal axon tract http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of axon tract. http://purl.obolibrary.org/obo/PLANP_0000365 abnormal peripheral nervous system http://purl.obolibrary.org/obo/PLANP_0000199 abnormal nervous system Abnormality of peripheral nervous system. http://purl.obolibrary.org/obo/PLANP_0000366 abnormal cell projection http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of cell projection. http://purl.obolibrary.org/obo/PLANP_0000367 abnormal commissural neuron http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron Abnormality of commissural neuron. http://purl.obolibrary.org/obo/PLANP_0000370 abnormal pax3/7+ neural progenitor cell http://purl.obolibrary.org/obo/PLANP_0000238 abnormal central nervous system Abnormality of pax3/7+ neural progenitor cell. http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue http://purl.obolibrary.org/obo/PLANP_0000410 abnormal multicellular anatomical structure Abnormality of tissue. http://purl.obolibrary.org/obo/PLANP_0000373 abnormal intracellular organelle http://purl.obolibrary.org/obo/PLANP_0000358 abnormal intracellular part Abnormality of intracellular organelle. http://purl.obolibrary.org/obo/PLANP_0000374 abnormal secretory vesicle http://purl.obolibrary.org/obo/PLANP_0000398 abnormal intracellular membrane-bounded organelle Abnormality of secretory vesicle. http://purl.obolibrary.org/obo/PLANP_0000375 abnormal optic cup http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of optic cup. http://purl.obolibrary.org/obo/PLANP_0000376 abnormal pharynx circular muscle cell http://purl.obolibrary.org/obo/PLANP_0000091 abnormal muscle cell Abnormality of pharynx circular muscle cell. http://purl.obolibrary.org/obo/PLANP_0000378 abnormal enteric neuron http://purl.obolibrary.org/obo/PLANP_0000070 abnormal autonomic neuron Abnormality of enteric neuron. http://purl.obolibrary.org/obo/PLANP_0000379 abnormal embryonic cell http://purl.obolibrary.org/obo/PLANP_0000363 abnormal cell Abnormality of embryonic cell. http://purl.obolibrary.org/obo/PLANP_0000380 abnormal Smed asexual biotype http://purl.obolibrary.org/obo/PLANP_0000305 abnormal biotype Abnormality of Smed asexual biotype. http://purl.obolibrary.org/obo/PLANP_0000381 abnormal integumental system http://purl.obolibrary.org/obo/PLANP_0000202 abnormal anatomical system Abnormality of integumental system. http://purl.obolibrary.org/obo/PLANP_0000383 abnormal cement gland http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of cement gland. http://purl.obolibrary.org/obo/PLANP_0000384 abnormal secretory system http://purl.obolibrary.org/obo/PLANP_0000202 abnormal anatomical system Abnormality of secretory system. http://purl.obolibrary.org/obo/PLANP_0000386 abnormal elongate spermatid http://purl.obolibrary.org/obo/PLANP_0000221 abnormal spermatid Abnormality of elongate spermatid. http://purl.obolibrary.org/obo/PLANP_0000387 abnormal lysosome http://purl.obolibrary.org/obo/PLANP_0000398 abnormal intracellular membrane-bounded organelle Abnormality of lysosome. http://purl.obolibrary.org/obo/PLANP_0000388 abnormal membrane part http://purl.obolibrary.org/obo/PLANP_0000229 abnormal membrane Abnormality of membrane part. http://purl.obolibrary.org/obo/PLANP_0000391 abnormal Stage 7 http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of Stage 7. http://purl.obolibrary.org/obo/PLANP_0000392 abnormal body wall musculature http://purl.obolibrary.org/obo/PLANP_0000186 abnormal musculature system Abnormality of body wall musculature. http://purl.obolibrary.org/obo/PLANP_0000393 abnormal dorsal-ventral axis http://purl.obolibrary.org/obo/PLANP_0000542 abnormal whole organism Abnormality of dorsal-ventral axis of the whole animal. http://purl.obolibrary.org/obo/PLANP_0000394 abnormal embryonic pharynx lumen epithelial surface http://purl.obolibrary.org/obo/PLANP_0000109 abnormal embryonic pharynx Abnormality of embryonic pharynx lumen epithelial surface. http://purl.obolibrary.org/obo/PLANP_0000396 abnormal pharynx inner epithelium http://purl.obolibrary.org/obo/PLANP_0000051 abnormal definitive pharynx Abnormality of pharynx inner epithelium. http://purl.obolibrary.org/obo/PLANP_0000397 abnormal circular muscle cell http://purl.obolibrary.org/obo/PLANP_0000392 abnormal body wall musculature Abnormality of circular muscle cell. http://purl.obolibrary.org/obo/PLANP_0000398 abnormal intracellular membrane-bounded organelle http://purl.obolibrary.org/obo/PLANP_0000373 abnormal intracellular organelle Abnormality of intracellular membrane-bounded organelle. http://purl.obolibrary.org/obo/PLANP_0000399 abnormal oogonial stem cell http://purl.obolibrary.org/obo/PLANP_0000437 abnormal female germ cell Abnormality of oogonial stem cell. http://purl.obolibrary.org/obo/PLANP_0000403 abnormal octopaminergic neuron http://purl.obolibrary.org/obo/PLANP_0000309 abnormal neurosecretory neuron Abnormality of octopaminergic neuron. http://purl.obolibrary.org/obo/PLANP_0000404 abnormal gonopore http://purl.obolibrary.org/obo/PLANP_0000065 abnormal copulatory apparatus Abnormality of gonopore. http://purl.obolibrary.org/obo/PLANP_0000406 abnormal flame bulb http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of flame bulb. http://purl.obolibrary.org/obo/PLANP_0000407 abnormal cholinergic neuron http://purl.obolibrary.org/obo/PLANP_0000309 abnormal neurosecretory neuron Abnormality of cholinergic neuron. http://purl.obolibrary.org/obo/PLANP_0000409 abnormal visceral musculature http://purl.obolibrary.org/obo/PLANP_0000186 abnormal musculature system Abnormality of visceral musculature. http://purl.obolibrary.org/obo/PLANP_0000410 abnormal multicellular anatomical structure http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype Abnormality of multicellular anatomical structure. http://purl.obolibrary.org/obo/PLANP_0000411 abnormal tertiary gut branch http://purl.obolibrary.org/obo/PLANP_0000666 abnormal gut branch Abnormality of tertiary gut branch. http://purl.obolibrary.org/obo/PLANP_0000412 abnormal lateral nerve http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of lateral nerve. http://purl.obolibrary.org/obo/PLANP_0000413 abnormal pharynx outer circular muscle cell http://purl.obolibrary.org/obo/PLANP_0000376 abnormal pharynx circular muscle cell Abnormality of pharynx outer circular muscle cell. http://purl.obolibrary.org/obo/PLANP_0000415 abnormal transverse commissure http://purl.obolibrary.org/obo/PLANP_0000164 abnormal ventral nerve cord Abnormality of transverse commissure. http://purl.obolibrary.org/obo/PLANP_0000416 abnormal sensory neuron http://purl.obolibrary.org/obo/PLANP_0000354 abnormal afferent neuron Abnormality of sensory neuron. http://purl.obolibrary.org/obo/PLANP_0000417 abnormal gastrodermal plexus http://purl.obolibrary.org/obo/PLANP_0000352 abnormal nerve plexus Abnormality of gastrodermal plexus. http://purl.obolibrary.org/obo/PLANP_0000420 abnormal cell junction http://purl.obolibrary.org/obo/PLANP_0000110 abnormal cell-cell contact zone Abnormality of cell junction. http://purl.obolibrary.org/obo/PLANP_0000421 abnormal primitive gut cell http://purl.obolibrary.org/obo/PLANP_0000059 abnormal extraembryonic cell Abnormality of primitive gut cell. http://purl.obolibrary.org/obo/PLANP_0000425 abnormal ectolecithal embryo http://purl.obolibrary.org/obo/PLANP_0000289 abnormal embryo Abnormality of ectolecithal embryo. http://purl.obolibrary.org/obo/PLANP_0000427 abnormal epidermis http://purl.obolibrary.org/obo/PLANP_0000381 abnormal integumental system Abnormality of epidermis. http://purl.obolibrary.org/obo/PLANP_0000430 abnormal nu neoblast http://purl.obolibrary.org/obo/PLANP_0000199 abnormal nervous system Abnormality of nu neoblast. http://purl.obolibrary.org/obo/PLANP_0000433 abnormal ovarian somatic gonadal cell http://purl.obolibrary.org/obo/PLANP_0000268 abnormal terminally differentiated cell Abnormality of ovarian somatic gonadal cell. http://purl.obolibrary.org/obo/PLANP_0000434 abnormal sperm duct epithelial cell http://purl.obolibrary.org/obo/PLANP_0000150 abnormal ciliated epithelial cell Abnormality of sperm duct epithelial cell. http://purl.obolibrary.org/obo/PLANP_0000435 abnormal primitive ectoderm http://purl.obolibrary.org/obo/PLANP_0000667 abnormal extraembryonic organ Abnormality of primitive ectoderm. http://purl.obolibrary.org/obo/PLANP_0000436 abnormal pharynx outer epithelium http://purl.obolibrary.org/obo/PLANP_0000051 abnormal definitive pharynx Abnormality of pharynx outer epithelium. http://purl.obolibrary.org/obo/PLANP_0000437 abnormal female germ cell http://purl.obolibrary.org/obo/PLANP_0000288 abnormal germ cell Abnormality of female germ cell. http://purl.obolibrary.org/obo/PLANP_0000438 abnormal collecting duct epithelial cell http://purl.obolibrary.org/obo/PLANP_0000211 abnormal non ciliated epithelial cell Abnormality of collecting duct epithelial cell. http://purl.obolibrary.org/obo/PLANP_0000439 abnormal mouth http://purl.obolibrary.org/obo/PLANP_0000285 abnormal digestive system Abnormality of mouth. http://purl.obolibrary.org/obo/PLANP_0000442 abnormal circular muscle progenitor cell http://purl.obolibrary.org/obo/PLANP_0000312 abnormal muscle progenitor Abnormality of circular muscle progenitor cell. http://purl.obolibrary.org/obo/PLANP_0000443 abnormal embryonic pharynx epithelial cell http://purl.obolibrary.org/obo/PLANP_0000310 abnormal epithelial cell Abnormality of embryonic pharynx epithelial cell. http://purl.obolibrary.org/obo/PLANP_0000444 abnormal pharynx pouch cavity http://purl.obolibrary.org/obo/PLANP_0000185 abnormal pharynx pouch Abnormality of pharynx pouch cavity. http://purl.obolibrary.org/obo/PLANP_0000445 abnormal spermatocyte http://purl.obolibrary.org/obo/PLANP_0000280 abnormal testis Abnormality of spermatocyte. http://purl.obolibrary.org/obo/PLANP_0000448 abnormal pharynx progenitor cell http://purl.obolibrary.org/obo/PLANP_0000304 abnormal progenitor cell Abnormality of pharynx progenitor cell. http://purl.obolibrary.org/obo/PLANP_0000450 abnormal excitatory motor neuron http://purl.obolibrary.org/obo/PLANP_0000242 abnormal motor neuron Abnormality of excitatory motor neuron. http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron http://purl.obolibrary.org/obo/PLANP_0000196 abnormal electrically signaling cell Abnormality of neuron. http://purl.obolibrary.org/obo/PLANP_0000455 abnormal diagonal muscle cell http://purl.obolibrary.org/obo/PLANP_0000392 abnormal body wall musculature Abnormality of diagonal muscle cell. http://purl.obolibrary.org/obo/PLANP_0000456 abnormal nerve http://purl.obolibrary.org/obo/PLANP_0000372 abnormal tissue Abnormality of nerve. http://purl.obolibrary.org/obo/PLANP_0000458 abnormal sympathetic neuron http://purl.obolibrary.org/obo/PLANP_0000452 abnormal neuron Abnormality of sympathetic neuron. http://purl.obolibrary.org/obo/PLANP_0000461 abnormal secretory pore http://purl.obolibrary.org/obo/PLANP_0000628 abnormal pore Abnormality of secretory pore. http://purl.obolibrary.org/obo/PLANP_0000462 abnormal blastema http://purl.obolibrary.org/obo/PLANP_0000678 abnormal regenerating fragment Abnormality of blastema. http://purl.obolibrary.org/obo/PLANP_0000463 abnormal embryonic pharynx radial muscle cell http://purl.obolibrary.org/obo/PLANP_0000109 abnormal embryonic pharynx Abnormality of embryonic pharynx radial muscle cell. http://purl.obolibrary.org/obo/PLANP_0000464 abnormal organelle membrane http://purl.obolibrary.org/obo/PLANP_0000229 abnormal membrane Abnormality of organelle membrane. http://purl.obolibrary.org/obo/PLANP_0000465 abnormal pharynx outer epithelium surface http://purl.obolibrary.org/obo/PLANP_0000436 abnormal pharynx outer epithelium Abnormality of pharynx outer epithelium surface. http://purl.obolibrary.org/obo/PLANP_0000467 abnormal morphology of primitive ectoderm surface http://purl.obolibrary.org/obo/PLANP_0000027 abnormal primitive ectoderm surface Any unspecified morphological anomaly of the primitive ectoderm surface, such as, for example, abnormal shape or colour. http://purl.obolibrary.org/obo/PLANP_0000469 abnormal morphology of lumen gut surface http://purl.obolibrary.org/obo/PLANP_0000048 abnormal gastrodermis surface Any unspecified morphological anomaly of the gastrodermis surface, such as, for example, abnormal shape or colour. http://purl.obolibrary.org/obo/PLANP_0000470 abnormal morphology of basal epidermis surface http://purl.obolibrary.org/obo/PLANP_0000071 abnormal basal surface of the epidermis Any unspecified morphological anomaly of the basal surface of the epidermis, such as, for example, abnormal shape or colour. http://purl.obolibrary.org/obo/PLANP_0000475 abnormal morphology of apical epidermis surface http://purl.obolibrary.org/obo/PLANP_0000243 abnormal apical surface of the epidermis Any unspecified morphological anomaly of the apical surface of the epidermis, such as, for example, abnormal shape or colour. http://purl.obolibrary.org/obo/PLANP_0000480 abnormal morphology of pharyngeal pouch surface http://purl.obolibrary.org/obo/PLANP_0000296 abnormal pharynx pouch epithelial surface Any unspecified morphological anomaly of the pharynx pouch epithelial surface, such as, for example, abnormal shape or colour. http://purl.obolibrary.org/obo/PLANP_0000481 abnormal morphology of embryonic gut cell surface http://purl.obolibrary.org/obo/PLANP_0000297 abnormal embryonic gut cell surface Any unspecified morphological anomaly of the embryonic gut cell surface, such as, for example, abnormal shape or colour. http://purl.obolibrary.org/obo/PLANP_0000482 abnormal morphology of primtive gut cell surface http://purl.obolibrary.org/obo/PLANP_0000327 abnormal primtive gut cell surface Any unspecified morphological anomaly of the primtive gut cell surface, such as, for example, abnormal shape or colour. http://purl.obolibrary.org/obo/PLANP_0000484 abnormal morphology of pharynx lumen epithelial surface http://purl.obolibrary.org/obo/PLANP_0000348 abnormal pharynx lumen epithelial surface Any unspecified morphological anomaly of the pharynx inner epithelium surface, such as, for example, abnormal shape or colour. http://purl.obolibrary.org/obo/PLANP_0000486 abnormal morphology of temporary embryonic pharynx lumen epithelial surface http://purl.obolibrary.org/obo/PLANP_0000394 abnormal embryonic pharynx lumen epithelial surface Any unspecified morphological anomaly of the embryonic pharynx lumen epithelial surface, such as, for example, abnormal shape or colour. http://purl.obolibrary.org/obo/PLANP_0000489 abnormal morphology of pharynx outer epithelial surface http://purl.obolibrary.org/obo/PLANP_0000465 abnormal pharynx outer epithelium surface Any unspecified morphological anomaly of the pharynx outer epithelium surface, such as, for example, abnormal shape or colour. http://purl.obolibrary.org/obo/PLANP_0000490 abormal shape of the ventral region of the animal http://purl.obolibrary.org/obo/PLANP_0000548 abnormal ventral region Any structural anomaly in the shape of the ventral region of the whole animal. http://purl.obolibrary.org/obo/PLANP_0000491 ventral curling http://purl.obolibrary.org/obo/PLANP_0000490 abormal shape of the ventral region of the animal Any structural anomaly that causes ventral region of the whole animal to be curled shaped. http://purl.obolibrary.org/obo/PLANP_0000492 pointy head http://purl.obolibrary.org/obo/PLANP_0000499 abnormal shape of head Any structural anomaly that causes head to be pointed shaped. http://purl.obolibrary.org/obo/PLANP_0000493 column-like head http://purl.obolibrary.org/obo/PLANP_0000499 abnormal shape of head Any structural anomaly that causes head to be columnar shaped. http://purl.obolibrary.org/obo/PLANP_0000494 skinny head http://purl.obolibrary.org/obo/PLANP_0000501 abnormal size of head skinny or decreased width of the head. http://purl.obolibrary.org/obo/PLANP_0000496 pointy tail http://purl.obolibrary.org/obo/PLANP_0000500 abnormal shape of tail Any structural anomaly that causes tail to be pointed shaped. http://purl.obolibrary.org/obo/PLANP_0000497 abnormal morphology of head http://purl.obolibrary.org/obo/PLANP_0000060 abnormal head Any unspecified morphological anomaly of the head, such as, for example, abnormal shape or colour. http://purl.obolibrary.org/obo/PLANP_0000498 abnormal morphology of tail http://purl.obolibrary.org/obo/PLANP_0000036 abnormal tail Any unspecified morphological anomaly of the tail, such as, for example, abnormal shape or colour. http://purl.obolibrary.org/obo/PLANP_0000499 abnormal shape of head http://purl.obolibrary.org/obo/PLANP_0000497 abnormal morphology of head Any structural anomaly in the shape of the head. http://purl.obolibrary.org/obo/PLANP_0000500 abnormal shape of tail http://purl.obolibrary.org/obo/PLANP_0000498 abnormal morphology of tail Any structural anomaly in the shape of the tail. http://purl.obolibrary.org/obo/PLANP_0000501 abnormal size of head http://purl.obolibrary.org/obo/PLANP_0000497 abnormal morphology of head A deviation from the normal size of the head. http://purl.obolibrary.org/obo/PLANP_0000502 abnormal size of tail http://purl.obolibrary.org/obo/PLANP_0000498 abnormal morphology of tail A deviation from the normal size of the tail. http://purl.obolibrary.org/obo/PLANP_0000503 skinny tail http://purl.obolibrary.org/obo/PLANP_0000502 abnormal size of tail skinny or decreased width of the tail. http://purl.obolibrary.org/obo/PLANP_0000504 star shaped lesion on the head http://purl.obolibrary.org/obo/PLANP_0000060 abnormal head An abnormal head with a lesion that is star shaped. http://purl.obolibrary.org/obo/PLANP_0000505 circular shaped lesion on the head http://purl.obolibrary.org/obo/PLANP_0000060 abnormal head An abnormal head with a lesion that is circular. http://purl.obolibrary.org/obo/PLANP_0000506 linear shaped lesion on the head http://purl.obolibrary.org/obo/PLANP_0000060 abnormal head An abnormal head with a lesion that is linear. http://purl.obolibrary.org/obo/PLANP_0000507 star shaped lesion on the tail http://purl.obolibrary.org/obo/PLANP_0000036 abnormal tail An abnormal tail with a lesion that is star shaped. http://purl.obolibrary.org/obo/PLANP_0000508 circular shaped lesion on the tail http://purl.obolibrary.org/obo/PLANP_0000036 abnormal tail An abnormal tail with a lesion that is circular. http://purl.obolibrary.org/obo/PLANP_0000509 linear shaped lesion on the tail http://purl.obolibrary.org/obo/PLANP_0000036 abnormal tail An abnormal tail with a lesion that is linear. http://purl.obolibrary.org/obo/PLANP_0000510 eyes further apart than normae http://purl.obolibrary.org/obo/PLANP_0000512 abnormal distance between eyes Increased distance between eye and eye. http://purl.obolibrary.org/obo/PLANP_0000511 eyes closer together than normal http://purl.obolibrary.org/obo/PLANP_0000512 abnormal distance between eyes Decreased distance between eye and eye. http://purl.obolibrary.org/obo/PLANP_0000512 abnormal distance between eyes http://purl.obolibrary.org/obo/PLANP_0000046 abnormal eye abnormal distance between eye and eye. http://purl.obolibrary.org/obo/PLANP_0000513 lesion in the head http://purl.obolibrary.org/obo/PLANP_0000497 abnormal morphology of head An abnormal head with one or more lesions. http://purl.obolibrary.org/obo/PLANP_0000514 lesion in the tail http://purl.obolibrary.org/obo/PLANP_0000498 abnormal morphology of tail An abnormal tail with one or more lesions. http://purl.obolibrary.org/obo/PLANP_0000515 loss of eyes http://purl.obolibrary.org/obo/PLANP_0000518 abnormal number of eyes Absence of eye. http://purl.obolibrary.org/obo/PLANP_0000518 abnormal number of eyes http://purl.obolibrary.org/obo/PLANP_0000046 abnormal eye Any structural anomaly that causes there to be an abnormal number eye. http://purl.obolibrary.org/obo/PLANP_0000519 decreased pigmentation of the eyes http://purl.obolibrary.org/obo/PLANP_0000534 abnormal pigmentation of the eyes Decreased or loss of pigmentation of eye. http://purl.obolibrary.org/obo/PLANP_0000520 loss of pigmentation in the eye http://purl.obolibrary.org/obo/PLANP_0000534 abnormal pigmentation of the eyes complete loss of pigmenation of the eye. http://purl.obolibrary.org/obo/PLANP_0000521 short tail http://purl.obolibrary.org/obo/PLANP_0000502 abnormal size of tail Decreased length or shortening of the tail. http://purl.obolibrary.org/obo/PLANP_0000522 long head http://purl.obolibrary.org/obo/PLANP_0000501 abnormal size of head longer, increased length of, head http://purl.obolibrary.org/obo/PLANP_0000523 long tail http://purl.obolibrary.org/obo/PLANP_0000502 abnormal size of tail longer, increased length of, tail http://purl.obolibrary.org/obo/PLANP_0000524 wide head http://purl.obolibrary.org/obo/PLANP_0000501 abnormal size of head Increased width of head. http://purl.obolibrary.org/obo/PLANP_0000525 wide tail http://purl.obolibrary.org/obo/PLANP_0000502 abnormal size of tail Increased width of tail. http://purl.obolibrary.org/obo/PLANP_0000526 abnormal number of heads http://purl.obolibrary.org/obo/PLANP_0000060 abnormal head Any structural anomaly that causes there to be an abnormal number head. http://purl.obolibrary.org/obo/PLANP_0000527 more heads http://purl.obolibrary.org/obo/PLANP_0000526 abnormal number of heads The presence of an increased number of head. http://purl.obolibrary.org/obo/PLANP_0000529 loss of head http://purl.obolibrary.org/obo/PLANP_0000526 abnormal number of heads Absence of head. http://purl.obolibrary.org/obo/PLANP_0000530 abnormal number of tails http://purl.obolibrary.org/obo/PLANP_0000036 abnormal tail Any structural anomaly that causes there to be an abnormal number tail. http://purl.obolibrary.org/obo/PLANP_0000531 more tails http://purl.obolibrary.org/obo/PLANP_0000530 abnormal number of tails The presence of an increased number of tail. http://purl.obolibrary.org/obo/PLANP_0000533 loss of tail http://purl.obolibrary.org/obo/PLANP_0000530 abnormal number of tails Absence of tail. http://purl.obolibrary.org/obo/PLANP_0000534 abnormal pigmentation of the eyes http://purl.obolibrary.org/obo/PLANP_0000046 abnormal eye abnormal degree of pigmentation of the eye. http://purl.obolibrary.org/obo/PLANP_0000535 abnormal pigmentation of the epidermis http://purl.obolibrary.org/obo/PLANP_0000427 abnormal epidermis abnormal degree of pigmentation of the epidermis. http://purl.obolibrary.org/obo/PLANP_0000536 decreased pigmentation of the epidermis http://purl.obolibrary.org/obo/PLANP_0000535 abnormal pigmentation of the epidermis Decreased or loss of pigmentation of epidermis. http://purl.obolibrary.org/obo/PLANP_0000537 less eyes http://purl.obolibrary.org/obo/PLANP_0000518 abnormal number of eyes The presence of a reduced number of eye. http://purl.obolibrary.org/obo/PLANP_0000538 less heads http://purl.obolibrary.org/obo/PLANP_0000526 abnormal number of heads The presence of a reduced number of head. http://purl.obolibrary.org/obo/PLANP_0000539 loss of pigmentation in the epidermis http://purl.obolibrary.org/obo/PLANP_0000535 abnormal pigmentation of the epidermis complete loss of pigmenation of the epidermis. http://purl.obolibrary.org/obo/PLANA_0000136 whole organism http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Anatomical structure that is an individual member of of Schmidtea mediterranea or any other flatworm of the class Turbellaria. http://purl.obolibrary.org/obo/PLANA_0000137 regeneration http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass). http://purl.obolibrary.org/obo/PLANA_0000135 female primordial germ cell http://purl.obolibrary.org/obo/PLANA_0000121 stem cell Cells expressing nanos that are located ventrally in the location that the ovaries form. Primordial germ cells are present in both asexual adults and sexual hermaphrodites. This term may be redundant with oogonial stem cell. http://purl.obolibrary.org/obo/PLANA_0003000 dorsal region of tail http://purl.obolibrary.org/obo/BFO_0000004 independent continuant The dorsal region of the tail. http://purl.obolibrary.org/obo/GO_0062033 positive regulation of mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0033047 regulation of mitotic sister chromatid segregation Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis. http://purl.obolibrary.org/obo/GO_0061919 process utilizing autophagic mechanism http://purl.obolibrary.org/obo/GO_0009987 cellular process A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway. http://purl.obolibrary.org/obo/GO_0140321 negative regulation by symbiont of host autophagy http://purl.obolibrary.org/obo/GO_0075071 modulation by symbiont of host autophagy Any process in which a symbiont organism decreases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/PATO_0000068 qualitative http://purl.obolibrary.org/obo/PATO_0000001 quality http://purl.obolibrary.org/obo/UPHENO_0001001 phenotype http://purl.obolibrary.org/obo/PATO_0000001 quality http://purl.obolibrary.org/obo/PATO_0002062 physical quality of a process http://purl.obolibrary.org/obo/PATO_0001236 process quality http://purl.obolibrary.org/obo/PATO_0002290 aplastic/hypoplastic http://purl.obolibrary.org/obo/PATO_0001241 physical object quality http://purl.obolibrary.org/obo/BFO_0000141 immaterial entity http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/CARO_0030000 biological entity http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/BFO_0000016 disposition http://purl.obolibrary.org/obo/BFO_0000017 realizable entity http://purl.obolibrary.org/obo/BFO_0000019 quality http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant http://purl.obolibrary.org/obo/CARO_0001010 organism or virus or viroid http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/BFO_0000006 spatial region http://purl.obolibrary.org/obo/BFO_0000141 immaterial entity http://purl.obolibrary.org/obo/CL_0000540 neuron http://purl.obolibrary.org/obo/CL_0000000 cell http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity http://purl.obolibrary.org/obo/BSPO_0000066 lateral side http://purl.obolibrary.org/obo/BSPO_0000054 anatomical side http://purl.obolibrary.org/obo/BSPO_0000090 posterior compartment http://purl.obolibrary.org/obo/BSPO_0000086 anatomical compartment http://purl.obolibrary.org/obo/BSPO_0000094 dorsal/ventral compartment boundary http://purl.obolibrary.org/obo/BSPO_0000092 anatomical compartment boundary http://purl.obolibrary.org/obo/ENVO_01000254 environmental system http://purl.obolibrary.org/obo/RO_0002577 system http://purl.obolibrary.org/obo/CL_0000000 cell http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure http://purl.obolibrary.org/obo/BSPO_0000086 anatomical compartment http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure http://purl.obolibrary.org/obo/CARO_0000014 cell part http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure http://purl.obolibrary.org/obo/CARO_0010000 multicellular anatomical structure http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure http://purl.obolibrary.org/obo/BSPO_0000092 anatomical compartment boundary http://purl.obolibrary.org/obo/CARO_0000010 anatomical boundary http://purl.obolibrary.org/obo/PLANP_0000813 slow moving animal slower, decreased speed of, whole organism http://purl.obolibrary.org/obo/PLANP_0000814 fast moving animal faster, increased speed of, whole organism http://purl.obolibrary.org/obo/PLANA_0000021 biotype Organisms sharing a specified genotype or karyotype. http://purl.obolibrary.org/obo/BFO_0000002 continuant An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts. http://purl.obolibrary.org/obo/BFO_0000003 occurrent An entity that has temporal parts and that happens, unfolds or develops through time. http://purl.obolibrary.org/obo/GO_0120038 obsolete plasma membrane bounded cell projection part OBSOLETE. Any constituent part of a plasma membrane bounded cell projection, a prolongation or process extending from a cell, e.g. a cilium or axon. http://purl.obolibrary.org/obo/GO_0005575 cellular_component A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome). http://purl.obolibrary.org/obo/GO_0044421 obsolete extracellular region part OBSOLETE. Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite. http://purl.obolibrary.org/obo/GO_0044426 obsolete cell wall part OBSOLETE. Any constituent part of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A spatiotemporal region encompassing some part of the life cycle of an organism. http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. http://purl.obolibrary.org/obo/PLANA_0002122 perturbation An event or occurrence that causes damage to a tissue or organ. http://purl.obolibrary.org/obo/PLANA_0003100 testis cell cell which is part of the testis http://purl.obolibrary.org/obo/PLANA_0003101 ventral epidermis cell cell which is part of the ventral epidermis http://purl.obolibrary.org/obo/PLANA_0003102 visual system cell cell which is part of the visual system http://purl.obolibrary.org/obo/PLANA_0003103 eye cell cell which is part of the eye http://purl.obolibrary.org/obo/PLANA_0003104 enteric muscle cell cell which is part of the enteric musculature http://purl.obolibrary.org/obo/PLANA_0003105 dorsal epidermis cell cell which is part of the dorsal region of the epidermis http://purl.obolibrary.org/obo/PLANA_0003106 adhesion gland cell cell which is part of the adhesion gland http://purl.obolibrary.org/obo/PLANA_0003107 body wall muscle cell cell which is part of the body wall musculature http://purl.obolibrary.org/obo/PLANA_0003108 gastrodermal cell cell which is part of the gastrodermis http://purl.obolibrary.org/obo/PLANA_0003109 anterior pole cell cell which is part of the anterior pole http://purl.obolibrary.org/obo/PLANA_0003110 pharynx neuron neuron which is part of the pharynx http://purl.obolibrary.org/obo/PLANA_0003111 pharynx epithelial cell epithelial cell which is part of the pharynx http://purl.obolibrary.org/obo/PLANA_0003112 pharynx muscle cell muscle cell which is part of the pharynx http://purl.obolibrary.org/obo/PLANA_0003113 pharynx pouch epithelial cell epithelial cell which is part of the pharynx pouch http://purl.obolibrary.org/obo/PLANA_0003114 melanin pigment granule pigment granule which is part of the eumelanin http://purl.obolibrary.org/obo/PLANA_0003115 ommochrome pigment granule pigment granule which is part of the ommochrome pigment cell http://purl.obolibrary.org/obo/PLANA_0003116 parenchymal cell cell which is part of the parenchyma http://purl.obolibrary.org/obo/PLANA_0003200 G1 phase neoblast neoblast undergoing mitotic G1 phase http://purl.obolibrary.org/obo/PLANA_0003201 S phase neoblast neoblast undergoing mitotic S phase http://purl.obolibrary.org/obo/PLANA_0003202 G2 phase neoblast neoblast undergoing mitotic G2 phase http://purl.obolibrary.org/obo/PLANA_0003203 prophase neoblast neoblast undergoing mitotic prophase http://purl.obolibrary.org/obo/PLANA_0003204 metaphase neoblast neoblast undergoing mitotic metaphase http://purl.obolibrary.org/obo/PLANA_0003205 anaphase neoblast neoblast undergoing mitotic anaphase http://purl.obolibrary.org/obo/PLANA_0003206 telophase neoblast neoblast undergoing mitotic telophase http://purl.obolibrary.org/obo/PLANA_0003207 G1 phase spermatogonial stem cell spermatogonial stem cell undergoing mitotic G1 phase http://purl.obolibrary.org/obo/PLANA_0003208 S phase spermatogonial stem cell spermatogonial stem cell undergoing mitotic S phase http://purl.obolibrary.org/obo/PLANA_0003209 G2 phase spermatogonial stem cell spermatogonial stem cell undergoing mitotic G2 phase http://purl.obolibrary.org/obo/PLANA_0003210 prophase spermatogonial stem cell spermatogonial stem cell undergoing mitotic prophase http://purl.obolibrary.org/obo/PLANA_0003211 metaphase spermatogonial stem cell spermatogonial stem cell undergoing mitotic metaphase http://purl.obolibrary.org/obo/PLANA_0003212 anaphase spermatogonial stem cell spermatogonial stem cell undergoing mitotic anaphase http://purl.obolibrary.org/obo/PLANA_0003213 telophase spermatogonial stem cell spermatogonial stem cell undergoing mitotic telophase http://purl.obolibrary.org/obo/PLANA_0003214 G1 phase oogonial stem cell oogonial stem cell undergoing mitotic G1 phase http://purl.obolibrary.org/obo/PLANA_0003215 S phase oogonial stem cell oogonial stem cell undergoing mitotic S phase http://purl.obolibrary.org/obo/PLANA_0003216 G2 phase oogonial stem cell oogonial stem cell undergoing mitotic G2 phase http://purl.obolibrary.org/obo/PLANA_0003217 prophase oogonial stem cell oogonial stem cell undergoing mitotic prophase http://purl.obolibrary.org/obo/PLANA_0003218 metaphase oogonial stem cell oogonial stem cell undergoing mitotic metaphase http://purl.obolibrary.org/obo/PLANA_0003219 anaphase oogonial stem cell oogonial stem cell undergoing mitotic anaphase http://purl.obolibrary.org/obo/PLANA_0003220 telophase oogonial stem cell oogonial stem cell undergoing mitotic telophase http://purl.obolibrary.org/obo/PLANA_0003221 G1 phase spermatogonium spermatogonium undergoing mitotic G1 phase http://purl.obolibrary.org/obo/PLANA_0003222 S phase spermatogonium spermatogonium undergoing mitotic S phase http://purl.obolibrary.org/obo/PLANA_0003223 G2 phase spermatogonium spermatogonium undergoing mitotic G2 phase http://purl.obolibrary.org/obo/PLANA_0003224 prophase spermatogonium spermatogonium undergoing mitotic prophase http://purl.obolibrary.org/obo/PLANA_0003225 metaphase spermatogonia spermatogonium undergoing mitotic metaphase http://purl.obolibrary.org/obo/PLANA_0003226 anaphase spermatogonia spermatogonium undergoing mitotic anaphase http://purl.obolibrary.org/obo/PLANA_0003227 telophase spermatogonium spermatogonium undergoing mitotic telophase http://purl.obolibrary.org/obo/PLANA_0003228 G1 phase oogonial cell oogonial cell undergoing mitotic G1 phase http://purl.obolibrary.org/obo/PLANA_0003229 S phase oogonial cell oogonial cell undergoing mitotic S phase http://purl.obolibrary.org/obo/PLANA_0003230 G2 phase oogonial cell oogonial cell undergoing mitotic G2 phase http://purl.obolibrary.org/obo/PLANA_0003231 prophase oogonial cell oogonial cell undergoing mitotic prophase http://purl.obolibrary.org/obo/PLANA_0003232 metaphase oogonial cell oogonial cell undergoing mitotic metaphase http://purl.obolibrary.org/obo/PLANA_0003233 anaphase oogonial cell oogonial cell undergoing mitotic anaphase http://purl.obolibrary.org/obo/PLANA_0003234 telophase oogonial cell oogonial cell undergoing mitotic telophase http://purl.obolibrary.org/obo/PLANA_0003235 G1 phase germ cell cyst germ cell cyst undergoing mitotic G1 phase http://purl.obolibrary.org/obo/PLANA_0003236 S phase germ cell cyst germ cell cyst undergoing mitotic S phase http://purl.obolibrary.org/obo/PLANA_0003237 G2 phase germ cell cyst germ cell cyst undergoing mitotic G2 phase http://purl.obolibrary.org/obo/PLANA_0003238 prophase germ cell cyst germ cell cyst undergoing mitotic prophase http://purl.obolibrary.org/obo/PLANA_0003239 metaphase germ cell cyst germ cell cyst undergoing mitotic metaphase http://purl.obolibrary.org/obo/PLANA_0003240 anaphase germ cell cyst germ cell cyst undergoing mitotic anaphase http://purl.obolibrary.org/obo/PLANA_0003241 telophase germ cell cyst germ cell cyst undergoing mitotic telophase http://purl.obolibrary.org/obo/PLANA_0003242 meiotic S phase spermatocyte spermatocyte undergoing meiotic S phase http://purl.obolibrary.org/obo/PLANA_0003243 meiotic G1 phase spermatocyte spermatocyte undergoing meiotic G1 phase http://purl.obolibrary.org/obo/PLANA_0003244 meiotic G2 phase spermatocyte spermatocyte undergoing meiotic G2 phase http://purl.obolibrary.org/obo/PLANA_0003245 meiotic prophase I spermatocyte spermatocyte undergoing meiotic prophase I http://purl.obolibrary.org/obo/PLANA_0003246 leptotene stage spermatocyte spermatocyte undergoing leptotene http://purl.obolibrary.org/obo/PLANA_0003247 zygotene stage spermatocyte spermatocyte undergoing zygotene http://purl.obolibrary.org/obo/PLANA_0003248 pachytene stage spermatocyte spermatocyte undergoing pachytene http://purl.obolibrary.org/obo/PLANA_0003249 diplotene stage spermatocyte spermatocyte undergoing diplotene http://purl.obolibrary.org/obo/PLANA_0003250 diakinesis stage spermatocyte spermatocyte undergoing diakinesis http://purl.obolibrary.org/obo/PLANA_0003251 meiotic metaphase 1 stage spermatocyte spermatocyte undergoing meiotic metaphase I http://purl.obolibrary.org/obo/PLANA_0003252 meiotic anaphase I stage spermatocyte spermatocyte undergoing meiotic anaphase I http://purl.obolibrary.org/obo/PLANA_0003253 meiotic telophase I spermatocyte spermatocyte undergoing meiotic telophase I http://purl.obolibrary.org/obo/PLANA_0003254 meiosis II stage spermatocyte spermatocyte undergoing meiosis II cell cycle phase http://purl.obolibrary.org/obo/PLANA_0003255 meiotic prophase II spermatocyte spermatocyte undergoing meiotic prophase II http://purl.obolibrary.org/obo/PLANA_0003256 meiotic metaphase 2 spermatocyte spermatocyte undergoing meiotic metaphase II http://purl.obolibrary.org/obo/PLANA_0003257 meiotic anaphase II spermatocyte spermatocyte undergoing meiotic anaphase II http://purl.obolibrary.org/obo/PLANA_0003258 meiotic telophase II spermatocyte spermatocyte undergoing meiotic telophase II http://purl.obolibrary.org/obo/PLANA_0003600 head fragment A fragment derived from a prepharyngeal amputation encompassing the head. http://purl.obolibrary.org/obo/PLANA_0003601 trunk fragment A fragment derived from pre- and post-pharyngeal amputations, encompassing the pharynx and parapharyngeal region. http://purl.obolibrary.org/obo/PLANA_0003602 tail fragment A fragment derived from a postpharyngeal amputation encompassing the tail. http://purl.obolibrary.org/obo/PLANA_0003603 prepharyngeal fragment A fragment derived from two prepharyngeal amputations, removing the head and posterior regions of the animal. http://purl.obolibrary.org/obo/PLANA_0003604 postpharyngeal fragment A fragment derived from two postpharyngeal amputations, removing the anterior region and the tail tip. http://purl.obolibrary.org/obo/PLANA_0003605 anterior fragment A fragment encompassing all or part of the anterior region of the animal. http://purl.obolibrary.org/obo/PLANA_0003606 posterior fragment A fragment encompassing all or part of the posterior region of the animal. http://purl.obolibrary.org/obo/PLANA_0003607 lateral fragment A fragment derived from an amputation parallel to or along any edge, which overlaps the lateral region, dorso-lateral region, ventro-lateral region, antero-lateral margin, lateral margin, ventro-lateral margin, postero-lateral margin, dorso-lateral margin, antero-lateral region, postero-lateral region. [SMR: a fragment that encompasses the side of the animal, not necessarily longituduinal, or parallel to the midline] http://purl.obolibrary.org/obo/PLANA_0003608 longitudinal fragment a fragment derived from an amputation parallel to the midline. http://purl.obolibrary.org/obo/PLANA_0003609 plug fragment A 3D piece of tissue, usually though the whole depth of the animal encompassing both dorsal and ventral sides, often made with a biopsy punch. http://purl.obolibrary.org/obo/PLANA_0003610 wedge fragment A piece of tissue removed from the lateral margin at any given point that extendes interiorly to more medial structures. http://purl.obolibrary.org/obo/GO_0044420 obsolete extracellular matrix component OBSOLETE. Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants). http://purl.obolibrary.org/obo/GO_0044422 obsolete organelle part OBSOLETE. Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0044424 obsolete intracellular part OBSOLETE. Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. http://purl.obolibrary.org/obo/GO_0044425 obsolete membrane part OBSOLETE. Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. http://purl.obolibrary.org/obo/GO_0044428 obsolete nuclear part OBSOLETE. Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. http://purl.obolibrary.org/obo/GO_0044429 obsolete mitochondrial part OBSOLETE. Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. http://purl.obolibrary.org/obo/GO_0044430 obsolete cytoskeletal part OBSOLETE. Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice. http://purl.obolibrary.org/obo/GO_0044431 obsolete Golgi apparatus part OBSOLETE. Any constituent part of the Golgi apparatus, a compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. http://purl.obolibrary.org/obo/GO_0044432 obsolete endoplasmic reticulum part OBSOLETE. Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. http://purl.obolibrary.org/obo/GO_0044433 obsolete cytoplasmic vesicle part OBSOLETE. Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell. http://purl.obolibrary.org/obo/GO_0044435 obsolete plastid part OBSOLETE. Any constituent part of a plastid, a member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. http://purl.obolibrary.org/obo/GO_0044437 obsolete vacuolar part OBSOLETE. Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. http://purl.obolibrary.org/obo/GO_0044441 obsolete ciliary part OBSOLETE. Any constituent part of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. http://purl.obolibrary.org/obo/GO_0044444 obsolete cytoplasmic part OBSOLETE. Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. http://purl.obolibrary.org/obo/GO_0044445 obsolete cytosolic part OBSOLETE. Any constituent part of cytosol, that part of the cytoplasm that does not contain membranous or particulate subcellular components. http://purl.obolibrary.org/obo/GO_0044452 obsolete nucleolar part OBSOLETE. Any constituent part of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. http://purl.obolibrary.org/obo/GO_0044459 obsolete plasma membrane part OBSOLETE. Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. http://purl.obolibrary.org/obo/GO_0044463 obsolete cell projection part OBSOLETE. Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon. http://purl.obolibrary.org/obo/GO_0097458 obsolete neuron part OBSOLETE. Any constituent part of a neuron, the basic cellular unit of nervous tissue. A typical neuron consists of a cell body (often called the soma), an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. http://purl.obolibrary.org/obo/GO_0044215 obsolete other organism OBSOLETE. A secondary organism with which the first organism is interacting. http://purl.obolibrary.org/obo/GO_1902583 obsolete multi-organism intracellular transport OBSOLETE. An intracellular transport which involves another organism. http://purl.obolibrary.org/obo/GO_0044046 obsolete interaction with host via substance released outside of symbiont OBSOLETE. An interaction with the host organism mediated by a substance that is released by the other organism. This includes substances that are released via pathogen cell lysis. http://purl.obolibrary.org/obo/GO_0052048 obsolete interaction with host via secreted substance OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_1900402 obsolete regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of carbohydrate metabolic process. http://purl.obolibrary.org/obo/GO_0100017 obsolete negative regulation of cell-cell adhesion by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively_regulates single organismal cell-cell adhesion http://purl.obolibrary.org/obo/GO_0100020 obsolete regulation of transport by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates transport http://purl.obolibrary.org/obo/GO_0100023 obsolete regulation of meiotic nuclear division by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates meiotic nuclear division http://purl.obolibrary.org/obo/GO_0100024 obsolete regulation of carbohydrate metabolic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0100036 obsolete positive regulation of purine nucleotide biosynthetic process by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively_regulates purine nucleotide biosynthetic process http://purl.obolibrary.org/obo/GO_0100051 obsolete positive regulation of meiotic nuclear division by transcription from RNA polymerase II promoter OBSOLETE. Any transcription from RNA polymerase II promoter process that positively_regulates meiotic nuclear division http://purl.obolibrary.org/obo/GO_1900387 obsolete negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of cell-cell adhesion. http://purl.obolibrary.org/obo/GO_1900392 obsolete regulation of transport by negative regulation of transcription from RNA polymerase II promoter OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in regulation of transport. http://purl.obolibrary.org/obo/GO_1900418 obsolete positive regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of purine nucleotide biosynthetic process. http://purl.obolibrary.org/obo/GO_0044434 obsolete chloroplast part OBSOLETE. Any constituent part of a chloroplast, a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. http://purl.obolibrary.org/obo/GO_0044436 obsolete thylakoid part OBSOLETE. Any constituent part of a thylakoid, a sac-like vesicle that bears the photosynthetic pigments in photosynthetic organisms. http://purl.obolibrary.org/obo/GO_0044446 obsolete intracellular organelle part OBSOLETE. A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0044462 obsolete external encapsulating structure part OBSOLETE. Any constituent part of an external encapsulating structure, a structure that lies outside the plasma membrane and surrounds the entire cell. This does not include the periplasmic space but does include the outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria). http://purl.obolibrary.org/obo/GO_0097425 obsolete smooth endoplasmic reticulum part OBSOLETE. Any constituent part of the smooth endoplasmic reticulum (also called smooth ER, or SER). http://purl.obolibrary.org/obo/GO_0052047 obsolete symbiotic process mediated by secreted substance OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism, where the two organisms are in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0052097 obsolete interspecies quorum sensing OBSOLETE. The process in which a community of single-celled organisms of different species monitors population density by detecting the concentration of small diffusible signal molecules. http://purl.obolibrary.org/obo/GO_0052100 obsolete intraspecies quorum sensing OBSOLETE. The process in which single-celled organisms of the same species monitor population density by detecting the concentration of small, diffusible signal molecules. http://purl.obolibrary.org/obo/GO_0052106 obsolete quorum sensing involved in interaction with host OBSOLETE. The process in which a community of single-celled organisms living in intimate contact with a host organism monitors population density by detecting the concentration of small diffusible signal molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/PLANA_0000425 obsolete definitive anatomical structure http://purl.obolibrary.org/obo/PLANA_0000132 obsolete gametogenesis http://purl.obolibrary.org/obo/PLANA_0000209 obsolete developing anatomical structure http://purl.obolibrary.org/obo/PLANA_0000212 obsolete blastomere compartment http://purl.obolibrary.org/obo/PLANA_0000225 obsolete oviparity http://purl.obolibrary.org/obo/PLANA_0000226 obsolete cross-fertilization http://purl.obolibrary.org/obo/PLANA_0000242 obsolete anatomical cavity http://purl.obolibrary.org/obo/PLANA_0000400 obsolete anatomical entity http://purl.obolibrary.org/obo/PLANA_0000401 obsolete immaterial anatomical entity http://purl.obolibrary.org/obo/PLANA_0000402 obsolete anatomical point http://purl.obolibrary.org/obo/PLANA_0000403 obsolete anatomical space http://purl.obolibrary.org/obo/PLANA_0000416 obsolete organism subdivision http://purl.obolibrary.org/obo/PLANA_0000424 obsolete material anatomical entity http://purl.obolibrary.org/obo/PLANA_0000426 obsolete acellular anatomical structure http://purl.obolibrary.org/obo/PLANA_0000432 obsolete regenerating anatomical structure http://purl.obolibrary.org/obo/PLANA_0000433 obsolete cellular component http://purl.obolibrary.org/obo/PLANA_0000489 obsolete anatomical line http://purl.obolibrary.org/obo/PLANA_0000490 obsolete anatomical plane http://purl.obolibrary.org/obo/PLANA_0000491 obsolete plane of autotomy http://purl.obolibrary.org/obo/PLANA_0000493 obsolete nervous system commissure http://purl.obolibrary.org/obo/PLANA_0000496 obsolete anatomical boundary http://purl.obolibrary.org/obo/PLANA_0000497 obsolete anatomical junction http://purl.obolibrary.org/obo/PLANA_0000498 obsolete main body axis http://purl.obolibrary.org/obo/PLANA_0000500 obsolete cell part http://purl.obolibrary.org/obo/PLANA_0000503 obsolete cilium http://purl.obolibrary.org/obo/PLANA_0000511 obsolete acidophilic cytoplasm http://purl.obolibrary.org/obo/PLANA_0000512 obsolete basophilic cytoplasm http://purl.obolibrary.org/obo/PLANA_0000516 obsolete cytoskeleton organization http://purl.obolibrary.org/obo/PLANA_0007502 obsolete coronal plane http://purl.obolibrary.org/obo/PLANA_0007504 obsolete dorsal compartment http://purl.obolibrary.org/obo/PLANA_0007505 obsolete ventral compartment http://purl.obolibrary.org/obo/PLANA_0007506 obsolete anterior compartment http://purl.obolibrary.org/obo/PLANA_0007507 obsolete posterior compartment http://purl.obolibrary.org/obo/PLANA_0007508 obsolete extracellular component http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/PLANA_0000037 obsolete definitive tissue http://purl.obolibrary.org/obo/PLANA_0000040 obsolete Schmidtea mediterranea developmental stage http://purl.obolibrary.org/obo/PLANA_0000051 obsolete direct development http://purl.obolibrary.org/obo/PLANA_0000052 obsolete dispersed cleavage http://purl.obolibrary.org/obo/PLANA_0000057 obsolete embryonic cleavage http://purl.obolibrary.org/obo/PLANA_0000086 obsolete protosphere http://purl.obolibrary.org/obo/PLANA_0000091 obsolete sphere formation http://purl.obolibrary.org/obo/PLANA_0000094 obsolete tissue morphogenesis http://purl.obolibrary.org/obo/PLANA_0000109 obsolete anatomical compartment subdivision feature http://purl.obolibrary.org/obo/PLANA_0000112 obsolete Schmidtea mediterranea developmental term http://purl.obolibrary.org/obo/PLANA_0000129 obsolete anatomical structure http://purl.obolibrary.org/obo/PLANA_0000082 obsolete racing stripe http://purl.obolibrary.org/obo/PLANA_0007554 obsolete parenchymal compartment http://purl.obolibrary.org/obo/PLANA_0007545 obsolete epidermal compartment http://purl.obolibrary.org/obo/PLANA_0007537 obsolete brain http://purl.obolibrary.org/obo/PLANA_0007549 obsolete body wall musculature compartment http://purl.obolibrary.org/obo/PLANP_00000000 Planarian Phenotype http://purl.obolibrary.org/obo/PLANP_0000018 obsolete abnormal gastrovascular compartment http://purl.obolibrary.org/obo/PLANP_0000049 obsolete abnormal plane of autonomy http://purl.obolibrary.org/obo/PLANP_0000062 obsolete abnormal Schmidtea mediterranea developmental term http://purl.obolibrary.org/obo/PLANP_0000064 obsolete abnormal dispersed cleavage http://purl.obolibrary.org/obo/PLANP_0000074 obsolete abnormal acidophilic cytoplasm http://purl.obolibrary.org/obo/PLANP_0000086 obsolete abnormal cytoskeleton organization http://purl.obolibrary.org/obo/PLANP_0000087 obsolete abnormal anatomical compartment subdivision feature http://purl.obolibrary.org/obo/PLANP_0000098 obsolete abnormal acellular anatomical structure http://purl.obolibrary.org/obo/PLANP_0000102 obsolete abnormal parenchymal compartment http://purl.obolibrary.org/obo/PLANP_0000201 obsolete abnormal oviparity http://purl.obolibrary.org/obo/PLANP_0000204 obsolete abnormal protosphere http://purl.obolibrary.org/obo/PLANP_0000223 obsolete abnormal direct development http://purl.obolibrary.org/obo/PLANP_0000236 obsolete abnormal tissue morphogenesis http://purl.obolibrary.org/obo/PLANP_0000240 obsolete abnormal gametogenesis http://purl.obolibrary.org/obo/PLANP_0000241 obsolete abnormal body wall musculature compartment http://purl.obolibrary.org/obo/PLANP_0000255 obsolete abnormal ventral compartment http://purl.obolibrary.org/obo/PLANP_0000259 obsolete abnormal embryonic cleavage http://purl.obolibrary.org/obo/PLANP_0000260 obsolete abnormal definitive anatomical structure http://purl.obolibrary.org/obo/PLANP_0000262 obsolete abnormal Schmidtea mediterranea developmental stage http://purl.obolibrary.org/obo/PLANP_0000324 obsolete abnormal sphere formation http://purl.obolibrary.org/obo/PLANP_0000326 obsolete abnormal basophilic cytoplasm http://purl.obolibrary.org/obo/PLANP_0000344 obsolete abnormal coronal plane http://purl.obolibrary.org/obo/PLANP_0000359 obsolete abnormal epidermal compartment http://purl.obolibrary.org/obo/PLANP_0000361 obsolete abnormal pharynx nerve plexus http://purl.obolibrary.org/obo/PLANP_0000449 obsolete abnormal racing stripe http://purl.obolibrary.org/obo/PLANP_0000459 obsolete abnormal cross-fertilization http://purl.obolibrary.org/obo/PLANA_0007560 obsolete gastrovascular compartment http://purl.obolibrary.org/obo/RO_0000052 inheres in http://purl.obolibrary.org/obo/RO_0002314 inheres in part of inheres_in a relation between a specifically dependent continuant (the dependent) and an independent continuant (the bearer), in which the dependent specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000080 quality of http://purl.obolibrary.org/obo/RO_0000052 inheres in quality_of a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000086 has quality http://purl.obolibrary.org/obo/RO_0000053 bearer of has_quality a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0002087 immediately_preceded_by http://purl.obolibrary.org/obo/BFO_0000062 preceded_by starts_at_end_of X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y) http://purl.obolibrary.org/obo/RO_0002218 obsolete has active participant http://purl.obolibrary.org/obo/RO_0000057 has participant has agent x has participant y if and only if x realizes some active role that inheres in y http://purl.obolibrary.org/obo/BFO_0000051 has_part http://purl.obolibrary.org/obo/RO_0002131 overlaps has_part Q1 has_part Q2 if and only if: every instance of Q1 is a quality_of an entity that has_quality some Q2. http://purl.obolibrary.org/obo/RO_0002436 molecularly interacts with http://purl.obolibrary.org/obo/RO_0002434 interacts with molecularly binds with An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other. http://purl.obolibrary.org/obo/RO_0002449 directly negatively regulates activity of http://purl.obolibrary.org/obo/RO_0002448 directly regulates activity of directly inhibits The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B. http://purl.obolibrary.org/obo/BFO_0000062 preceded_by http://purl.obolibrary.org/obo/RO_0002086 ends after preceded_by X preceded_by Y iff: end(Y) before_or_simultaneous_with start(X) http://purl.obolibrary.org/obo/RO_0002156 derived by descent from http://purl.obolibrary.org/obo/RO_0002320 evolutionarily related to evolutionarily_descended_from d derived_by_descent_from a if d is specified by some genetic program that is sequence-inherited-from a genetic program that specifies a. http://purl.obolibrary.org/obo/BFO_0000050 part_of http://purl.obolibrary.org/obo/RO_0002131 overlaps part_of a core relation that holds between a part and its whole http://purl.obolibrary.org/obo/RO_0002233 has input http://purl.obolibrary.org/obo/RO_0000057 has participant consumes p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p. http://purl.obolibrary.org/obo/RO_0002215 capable of http://purl.obolibrary.org/obo/RO_0002216 capable of part of has function realized in A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. http://purl.obolibrary.org/obo/RO_0002217 obsolete actively participates in http://purl.obolibrary.org/obo/RO_0000056 participates in agent in OBSOLETE x actively participates in y if and only if x participates in y and x realizes some active role http://purl.obolibrary.org/obo/RO_0002331 involved in http://purl.obolibrary.org/obo/RO_0002431 involved in or involved in regulation of enables part of c involved_in p if and only if c enables some process p', and p' is part of p http://purl.obolibrary.org/obo/RO_0002431 involved in or involved in regulation of http://purl.obolibrary.org/obo/RO_0002500 causal agent in process involved in or reguates c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p http://purl.obolibrary.org/obo/RO_0002216 capable of part of http://purl.obolibrary.org/obo/RO_0002500 causal agent in process has function in c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p. http://purl.obolibrary.org/obo/RO_0002329 part of structure that is capable of http://purl.obolibrary.org/obo/RO_0002328 functionally related to 0 this relation holds between c and p when c is part of some c', and c' is capable of p. http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within http://purl.obolibrary.org/obo/RO_0002501 causal relation between processes influences (processual) p 'causally upstream or within' q iff (1) the end of p is before the end of q and (2) the execution of p exerts some causal influence over the outputs of q; i.e. if p was abolished or the outputs of p were to be modified, this would necessarily affect q. http://purl.obolibrary.org/obo/RO_0002210 directly develops into http://purl.obolibrary.org/obo/RO_0002203 develops_into developmental precursor of inverse of directly develops from http://purl.obolibrary.org/obo/RO_0002224 starts with http://purl.obolibrary.org/obo/RO_0002222 temporally related to started by x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0002230 ends with http://purl.obolibrary.org/obo/RO_0002222 temporally related to finished by x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0002231 has start location http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in starts with process that occurs in x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y http://purl.obolibrary.org/obo/RO_0002232 has end location http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in ends with process that occurs in x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y http://purl.obolibrary.org/obo/RO_0002256 developmentally induced by http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by induced by t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor anatomical structure type T to T', where T' develops_from T http://purl.obolibrary.org/obo/RO_0002285 developmentally replaces http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by replaces x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else http://purl.obolibrary.org/obo/RO_0002432 is active in http://purl.obolibrary.org/obo/RO_0002328 functionally related to executes activity in c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure. http://purl.obolibrary.org/obo/RO_0002450 directly positively regulates activity of http://purl.obolibrary.org/obo/RO_0002448 directly regulates activity of directly activates The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B. http://purl.obolibrary.org/obo/RO_0004029 disease has feature http://purl.obolibrary.org/obo/RO_0040035 disease relationship A relationship between a disease and some feature of that disease, where the feature is either a phenotype or an isolated disease. http://purl.obolibrary.org/obo/RO_0002025 has effector activity http://purl.obolibrary.org/obo/RO_0002017 has component activity A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity. http://purl.obolibrary.org/obo/pato#decreased_in_magnitude_relative_to decreased_in_magnitude_relative_to http://purl.obolibrary.org/obo/pato#different_in_magnitude_relative_to different_in_magnitude_relative_to q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. http://purl.obolibrary.org/obo/pato#increased_in_magnitude_relative_to increased_in_magnitude_relative_to http://purl.obolibrary.org/obo/pato#different_in_magnitude_relative_to different_in_magnitude_relative_to q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. http://purl.obolibrary.org/obo/RO_0002160 only in taxon http://purl.obolibrary.org/obo/RO_0002162 in taxon x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z. http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by http://purl.obolibrary.org/obo/RO_0002324 developmentally related to Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p http://purl.obolibrary.org/obo/RO_0002162 in taxon http://purl.obolibrary.org/obo/RO_0002320 evolutionarily related to x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed. http://purl.obolibrary.org/obo/RO_0002286 developmentally succeeded by http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving Inverse of developmentally preceded by http://purl.obolibrary.org/obo/RO_0002371 attached to http://purl.obolibrary.org/obo/RO_0002177 attached to part of a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving http://purl.obolibrary.org/obo/RO_0002324 developmentally related to x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction). http://purl.obolibrary.org/obo/RO_0002388 has potential to directly develop into http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y http://purl.obolibrary.org/obo/RO_0002372 has muscle origin http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to. http://purl.obolibrary.org/obo/RO_0002374 derived from ancestral fusion of http://purl.obolibrary.org/obo/RO_0002156 derived by descent from x has_fused_element y iff: there exists some z : x has_part z, z homologous_to y, and y is a distinct element, the boundary between x and z is largely fiat http://purl.obolibrary.org/obo/BFO_0000063 precedes http://purl.obolibrary.org/obo/RO_0002222 temporally related to x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0002219 surrounded by http://purl.obolibrary.org/obo/RO_0002220 adjacent_to x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x http://purl.obolibrary.org/obo/RO_0002220 adjacent_to http://purl.obolibrary.org/obo/RO_0002163 spatially disjoint from x adjacent_to y iff: x and y share a boundary http://purl.obolibrary.org/obo/RO_0002223 starts http://purl.obolibrary.org/obo/BFO_0000050 part_of inverse of starts with http://purl.obolibrary.org/obo/RO_0002018 has component process http://purl.obolibrary.org/obo/RO_0002180 has component w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. http://purl.obolibrary.org/obo/RO_0002202 develops_from http://purl.obolibrary.org/obo/RO_0002254 has developmental contribution from x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y http://purl.obolibrary.org/obo/RO_0002333 enabled by http://purl.obolibrary.org/obo/RO_0002328 functionally related to inverse of enables http://purl.obolibrary.org/obo/RO_0002404 causally downstream of http://purl.obolibrary.org/obo/RO_0002427 causally downstream of or within inverse of upstream of http://purl.obolibrary.org/obo/RO_0002412 immediately causally upstream of http://purl.obolibrary.org/obo/RO_0002411 causally upstream of p is immediately causally upstream of q iff both (a) p immediately precedes q and (b) p is causally upstream of q. In addition, the output of p must be an input of q. http://purl.obolibrary.org/obo/RO_0002448 directly regulates activity of http://purl.obolibrary.org/obo/RO_0011002 regulates activity of The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B. A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B. http://purl.obolibrary.org/obo/RO_0002566 causally influences http://purl.obolibrary.org/obo/RO_0002506 causal relation between entities The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size). http://purl.obolibrary.org/obo/RO_0002490 existence overlaps http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y)) http://purl.obolibrary.org/obo/RO_0002263 acts upstream of http://purl.obolibrary.org/obo/RO_0002264 acts upstream of or within c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes. http://purl.obolibrary.org/obo/RO_0002131 overlaps http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to x overlaps y iff they have some part in common. http://purl.obolibrary.org/obo/RO_0002254 has developmental contribution from http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by x has developmental contribution from y iff x has some part z such that z develops from y http://purl.obolibrary.org/obo/RO_0002496 existence starts during or after http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y). http://purl.obolibrary.org/obo/RO_0002497 existence ends during or before http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends. http://purl.obolibrary.org/obo/BSPO_0000105 ipsilateral to http://purl.obolibrary.org/obo/BSPO_0000126 in lateral side of On the same side as. For example, the left arm is ipsilateral to the left leg. http://purl.obolibrary.org/obo/BSPO_0000113 opposite to http://purl.obolibrary.org/obo/BSPO_0000105 ipsilateral to Direcly opposite to. i.e. on the opposite side through the axis. http://purl.obolibrary.org/obo/BSPO_0000126 in lateral side of http://purl.obolibrary.org/obo/BFO_0000050 part_of X in lateral side of Y <=> if X is in left side of Y or X is in right side of Y. X is often, but not always a paired structure http://purl.obolibrary.org/obo/BSPO_0001107 immediately deep to http://purl.obolibrary.org/obo/BSPO_0000107 deep_to x immediately deep to y iff x deep_to y and x is contiguous with y. http://purl.obolibrary.org/obo/BSPO_0015014 immediately superficial to http://purl.obolibrary.org/obo/BSPO_0000108 superficial_to x immediately superficial to y iff x superficial to y and x is contiguous with y. http://purl.obolibrary.org/obo/RO_0011002 regulates activity of http://purl.obolibrary.org/obo/RO_0002566 causally influences The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B. http://purl.obolibrary.org/obo/RO_0002411 causally upstream of http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within p is causally upstream of q if and only if p precedes q and p and q are linked in a causal chain http://purl.obolibrary.org/obo/RO_0002211 regulates http://purl.obolibrary.org/obo/RO_0002411 causally upstream of process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2. http://purl.obolibrary.org/obo/RO_0002212 negatively regulates http://purl.obolibrary.org/obo/RO_0002211 regulates Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2. http://purl.obolibrary.org/obo/RO_0002213 positively regulates http://purl.obolibrary.org/obo/RO_0002211 regulates Process(P1) postively regulates process(P2) iff: P1 initiates P2, or P1 increases the the frequency of initiation of P2 or the magnitude or rate of output of P2. http://purl.obolibrary.org/obo/RO_0002180 has component http://purl.obolibrary.org/obo/BFO_0000051 has_part w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. http://purl.obolibrary.org/obo/RO_0002163 spatially disjoint from http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to A is spatially_disjoint_from B if and only if they have no parts in common http://purl.obolibrary.org/obo/RO_0002314 inheres in part of http://purl.obolibrary.org/obo/RO_0002502 depends on q inheres in part of w if and only if there exists some p such that q inheres in p and p part of w. http://purl.obolibrary.org/obo/RO_0002352 input of http://purl.obolibrary.org/obo/RO_0002328 functionally related to inverse of has input http://purl.obolibrary.org/obo/RO_0002473 composed primarily of http://purl.obolibrary.org/obo/BFO_0000051 has_part x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y. http://purl.obolibrary.org/obo/RO_0002104 has plasma membrane part http://purl.obolibrary.org/obo/BFO_0000051 has_part Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part. http://purl.obolibrary.org/obo/RO_0002203 develops_into http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into inverse of develops from http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving x has the potential to develop into y iff x develops into y or if x is capable of developing into y http://purl.obolibrary.org/obo/RO_0002023 directly negatively regulated by http://purl.obolibrary.org/obo/RO_0002022 directly regulated by Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1. http://purl.obolibrary.org/obo/RO_0002024 directly positively regulated by http://purl.obolibrary.org/obo/RO_0002022 directly regulated by Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1. http://purl.obolibrary.org/obo/RO_0002170 connected to http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b http://purl.obolibrary.org/obo/RO_0002177 attached to part of http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b. http://purl.obolibrary.org/obo/RO_0002264 acts upstream of or within http://purl.obolibrary.org/obo/RO_0002500 causal agent in process c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process. http://purl.obolibrary.org/obo/RO_0002503 towards http://purl.obolibrary.org/obo/RO_0002502 depends on q towards e2 if and only if q is a relational quality such that q inheres-in some e, and e != e2 and q is dependent on e2 http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to http://purl.obolibrary.org/obo/RO_0002328 functionally related to A relation that holds between elements of a musculoskeletal system or its analogs. http://purl.obolibrary.org/obo/RO_0002373 has muscle insertion http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone. http://purl.obolibrary.org/obo/RO_0002488 existence starts during http://purl.obolibrary.org/obo/RO_0002496 existence starts during or after x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y). http://purl.obolibrary.org/obo/RO_0002492 existence ends during http://purl.obolibrary.org/obo/RO_0002497 existence ends during or before x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y). http://purl.obolibrary.org/obo/RO_0002019 has ligand http://purl.obolibrary.org/obo/RO_0002233 has input A relationship that holds between between a receptor and an chemical entity, typically a small molecule or peptide, that carries information between cells or compartments of a cell and which binds the receptor and regulates its effector function. http://purl.obolibrary.org/obo/RO_0004031 enables subfunction http://purl.obolibrary.org/obo/RO_0002328 functionally related to Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P. http://purl.obolibrary.org/obo/RO_0004034 acts upstream of, positive effect http://purl.obolibrary.org/obo/RO_0004032 acts upstream of or within, positive effect c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive http://purl.obolibrary.org/obo/RO_0004035 acts upstream of, negative effect http://purl.obolibrary.org/obo/RO_0004033 acts upstream of or within, negative effect c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative http://purl.obolibrary.org/obo/RO_0002255 developmentally_contributes_to http://purl.obolibrary.org/obo/RO_0002385 has potential to developmentally contribute to inverse of has developmental contribution from http://purl.obolibrary.org/obo/RO_0002334 regulated by http://purl.obolibrary.org/obo/RO_0002427 causally downstream of or within inverse of regulates http://purl.obolibrary.org/obo/RO_0002335 negatively regulated by http://purl.obolibrary.org/obo/RO_0002334 regulated by inverse of negatively regulates http://purl.obolibrary.org/obo/RO_0002336 positively regulated by http://purl.obolibrary.org/obo/RO_0002334 regulated by inverse of positively regulates http://purl.obolibrary.org/obo/RO_0002379 spatially coextensive with http://purl.obolibrary.org/obo/RO_0002131 overlaps x spatially_coextensive_with y if and inly if x and y have the same location http://purl.obolibrary.org/obo/RO_0002385 has potential to developmentally contribute to http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y http://purl.obolibrary.org/obo/RO_0002427 causally downstream of or within http://purl.obolibrary.org/obo/RO_0002501 causal relation between processes inverse of causally upstream of or within http://purl.obolibrary.org/obo/RO_0002500 causal agent in process http://purl.obolibrary.org/obo/RO_0002595 causal relation between material entity and a process A relationship between a material entity and a process where the material entity has some causal role that influences the process http://purl.obolibrary.org/obo/RO_0002501 causal relation between processes http://purl.obolibrary.org/obo/RO_0002410 causally related to p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one of direct activation or direct inhibition. p may be upstream, downstream, part of or a container of q. http://purl.obolibrary.org/obo/RO_0002584 has part structure that is capable of http://purl.obolibrary.org/obo/RO_0002595 causal relation between material entity and a process s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p http://purl.obolibrary.org/obo/RO_0002595 causal relation between material entity and a process http://purl.obolibrary.org/obo/RO_0002410 causally related to A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity. http://purl.obolibrary.org/obo/RO_0002596 capable of regulating http://purl.obolibrary.org/obo/RO_0002500 causal agent in process Holds between c and p if and only if c is capable of some activity a, and a regulates p. http://purl.obolibrary.org/obo/RO_0002597 capable of negatively regulating http://purl.obolibrary.org/obo/RO_0002596 capable of regulating Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p. http://purl.obolibrary.org/obo/RO_0002598 capable of positively regulating http://purl.obolibrary.org/obo/RO_0002596 capable of regulating Holds between c and p if and only if c is capable of some activity a, and a positively regulates p. http://purl.obolibrary.org/obo/RO_0002608 process has causal agent http://purl.obolibrary.org/obo/RO_0002410 causally related to Inverse of 'causal agent in process' http://purl.obolibrary.org/obo/RO_0002015 has positive regulatory component activity http://purl.obolibrary.org/obo/RO_0002013 has regulatory component activity A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B. http://purl.obolibrary.org/obo/RO_0002013 has regulatory component activity http://purl.obolibrary.org/obo/RO_0002017 has component activity A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B. http://purl.obolibrary.org/obo/RO_0002014 has negative regulatory component activity http://purl.obolibrary.org/obo/RO_0002013 has regulatory component activity A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B. http://purl.obolibrary.org/obo/RO_0002157 has derived by descendant http://purl.obolibrary.org/obo/RO_0002320 evolutionarily related to inverse of derived by descent from http://purl.obolibrary.org/obo/RO_0002158 shares ancestor with http://purl.obolibrary.org/obo/RO_0002320 evolutionarily related to two individual entities d1 and d2 stand in a shares_ancestor_with relation if and only if there exists some a such that d1 derived_by_descent_from a and d2 derived_by_descent_from a. http://purl.obolibrary.org/obo/RO_0002207 directly develops from http://purl.obolibrary.org/obo/RO_0002202 develops_from Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participate in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of x comes from y, and the start of x is coincident with or after the end of y. http://purl.obolibrary.org/obo/RO_0002221 surrounds http://purl.obolibrary.org/obo/RO_0002220 adjacent_to inverse of surrounded by http://purl.obolibrary.org/obo/RO_0002225 develops from part of http://purl.obolibrary.org/obo/RO_0002202 develops_from x develops from part of y if and only if there exists some z such that x develops from z and z is part of y http://purl.obolibrary.org/obo/RO_0002226 develops in http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by x develops_in y if x is located in y whilst x is developing http://purl.obolibrary.org/obo/RO_0002229 ends http://purl.obolibrary.org/obo/BFO_0000050 part_of inverse of ends with http://purl.obolibrary.org/obo/RO_0002257 developmentally induces http://purl.obolibrary.org/obo/RO_0002386 has potential to developmentally induce Inverse of developmentally induced by http://purl.obolibrary.org/obo/RO_0002386 has potential to developmentally induce http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving x has potential to developmentally induce y iff x developmentally induces y or x is capable of developmentally inducing y http://purl.obolibrary.org/obo/RO_0002428 involved in regulation of http://purl.obolibrary.org/obo/RO_0002431 involved in or involved in regulation of c involved in regulation of p if c is involved in some p' and p' regulates some p http://purl.obolibrary.org/obo/RO_0002429 involved in positive regulation of http://purl.obolibrary.org/obo/RO_0002428 involved in regulation of c involved in regulation of p if c is involved in some p' and p' positively regulates some p http://purl.obolibrary.org/obo/RO_0002430 involved in negative regulation of http://purl.obolibrary.org/obo/RO_0002428 involved in regulation of c involved in regulation of p if c is involved in some p' and p' negatively regulates some p http://purl.obolibrary.org/obo/RO_0002578 directly regulates http://purl.obolibrary.org/obo/RO_0002211 regulates Process(P1) directly regulates process(P2) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2. http://purl.obolibrary.org/obo/RO_0002583 existence starts at end of http://purl.obolibrary.org/obo/RO_0002496 existence starts during or after holds between x and y if and only if the time point at which x starts is equivalent to the time point at which y ends. Formally: iff α(x) = ω(y). http://purl.obolibrary.org/obo/RO_0002593 existence ends at start of http://purl.obolibrary.org/obo/RO_0002497 existence ends during or before holds between x and y if and only if the time point at which x ends is equivalent to the time point at which y starts. Formally: iff ω(x) = α(y). http://purl.obolibrary.org/obo/RO_0002629 directly positively regulates http://purl.obolibrary.org/obo/RO_0002578 directly regulates Process(P1) directly postively regulates process(P2) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P1 directly positively regulates P2. http://purl.obolibrary.org/obo/RO_0002630 directly negatively regulates http://purl.obolibrary.org/obo/RO_0002578 directly regulates Process(P1) directly negatively regulates process(P2) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P1 directly negatively regulates P2. http://purl.obolibrary.org/obo/RO_0002081 before or simultaneous with http://purl.obolibrary.org/obo/RO_0002222 temporally related to <= http://purl.obolibrary.org/obo/RO_0002322 confers advantage in http://purl.obolibrary.org/obo/RO_0002321 ecologically related to adapted for http://purl.obolibrary.org/obo/RO_0002090 immediately precedes http://purl.obolibrary.org/obo/BFO_0000063 precedes meets http://purl.obolibrary.org/obo/RO_0002327 enables http://purl.obolibrary.org/obo/RO_0002215 capable of is executing http://purl.obolibrary.org/obo/RO_0002091 starts_during http://purl.obolibrary.org/obo/RO_0002222 temporally related to io http://purl.obolibrary.org/obo/RO_0002092 happens during http://purl.obolibrary.org/obo/RO_0002093 ends_during during http://purl.obolibrary.org/obo/RO_0002093 ends_during http://purl.obolibrary.org/obo/RO_0002222 temporally related to overlaps http://purl.obolibrary.org/obo/RO_0002085 encompasses http://purl.obolibrary.org/obo/RO_0002088 during which starts di http://purl.obolibrary.org/obo/RO_0002447 phosphorylates http://purl.obolibrary.org/obo/RO_0002436 molecularly interacts with An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y. http://purl.obolibrary.org/obo/RO_0002082 simultaneous with http://purl.obolibrary.org/obo/RO_0002081 before or simultaneous with http://purl.obolibrary.org/obo/RO_0002287 part of developmental precursor of http://purl.obolibrary.org/obo/RO_0002286 developmentally succeeded by http://purl.obolibrary.org/obo/RO_0002159 serially homologous to http://purl.obolibrary.org/obo/RO_0002320 evolutionarily related to http://purl.obolibrary.org/obo/RO_0002405 immediately causally downstream of http://purl.obolibrary.org/obo/RO_0002404 causally downstream of http://purl.obolibrary.org/obo/RO_0002017 has component activity http://purl.obolibrary.org/obo/RO_0002018 has component process http://purl.obolibrary.org/obo/RO_0002559 causally influenced by http://purl.obolibrary.org/obo/RO_0002506 causal relation between entities http://purl.obolibrary.org/obo/RO_0002563 interaction relation helper property http://purl.obolibrary.org/obo/RO_0002464 helper property (not for use in curation) http://purl.obolibrary.org/obo/RO_0002564 molecular interaction relation helper property http://purl.obolibrary.org/obo/RO_0002563 interaction relation helper property http://purl.obolibrary.org/obo/RO_0002465 is symbiosis http://purl.obolibrary.org/obo/RO_0002563 interaction relation helper property http://purl.obolibrary.org/obo/RO_0002481 is kinase activity http://purl.obolibrary.org/obo/RO_0002564 molecular interaction relation helper property http://purl.obolibrary.org/obo/RO_0002086 ends after http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/RO_0002084 during which ends http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/RO_0002088 during which starts http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/RO_0002304 causally upstream of, positive effect http://purl.obolibrary.org/obo/RO_0004047 causally upstream of or within, positive effect http://purl.obolibrary.org/obo/RO_0002305 causally upstream of, negative effect http://purl.obolibrary.org/obo/RO_0004046 causally upstream of or within, negative effect http://purl.obolibrary.org/obo/RO_0004033 acts upstream of or within, negative effect http://purl.obolibrary.org/obo/RO_0002264 acts upstream of or within http://purl.obolibrary.org/obo/RO_0004032 acts upstream of or within, positive effect http://purl.obolibrary.org/obo/RO_0002264 acts upstream of or within http://purl.obolibrary.org/obo/RO_0002326 contributes to http://purl.obolibrary.org/obo/RO_0002329 part of structure that is capable of http://purl.obolibrary.org/obo/RO_0002022 directly regulated by http://purl.obolibrary.org/obo/RO_0002334 regulated by http://purl.obolibrary.org/obo/RO_0002506 causal relation between entities http://purl.obolibrary.org/obo/RO_0002410 causally related to http://purl.obolibrary.org/obo/RO_0004046 causally upstream of or within, negative effect http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within http://purl.obolibrary.org/obo/RO_0004047 causally upstream of or within, positive effect http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within http://purl.obolibrary.org/obo/RO_0000053 bearer of is bearer of a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000056 participates in participates_in a relation between a continuant and a process, in which the continuant is somehow involved in the process http://purl.obolibrary.org/obo/RO_0000057 has participant has_participant a relation between a process and a continuant, in which the continuant is somehow involved in the process http://purl.obolibrary.org/obo/RO_0001000 derives from derives_from a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity http://purl.obolibrary.org/obo/RO_0001001 derives into derives_into a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity http://purl.obolibrary.org/obo/RO_0001015 location of location_of a relation between two independent continuants, the location and the target, in which the target is entirely within the location http://purl.obolibrary.org/obo/RO_0001025 located in located_in a relation between two independent continuants, the target and the location, in which the target is entirely within the location http://purl.obolibrary.org/obo/BFO_0000066 occurs in unfolds_in b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t http://purl.obolibrary.org/obo/PLANA_0007536 specific_to Restricted to domain http://purl.obolibrary.org/obo/pato#different_in_magnitude_relative_to different_in_magnitude_relative_to q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. http://purl.obolibrary.org/obo/pato#has_cross_section has_cross_section s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2. http://purl.obolibrary.org/obo/pato#reciprocal_of reciprocal_of q1 reciprocal_of q2 if and only if : q1 and q2 are relational qualities and a phenotype e q1 e2 mutually implies a phenotype e2 q2 e. http://purl.obolibrary.org/obo/RO_0002320 evolutionarily related to A relationship that holds via some environmental process http://purl.obolibrary.org/obo/RO_0002324 developmentally related to A relationship that holds between entities participating in some developmental process (GO:0032502) http://purl.obolibrary.org/obo/BFO_0000067 contains process [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t http://purl.obolibrary.org/obo/IAO_0000136 is about is_about is a (currently) primitive relation that relates an information artifact to an entity. http://purl.obolibrary.org/obo/RO_0002200 has phenotype A relationship that holds between a biological entity and a phenotype. Here a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature). The subject of this relationship can be an organism (where the organism has the phenotype, i.e. the qualities inhere in parts of this organism), a genomic entity such as a gene or genotype (if modifications of the gene or the genotype causes the phenotype), or a condition such as a disease (such that if the condition inheres in an organism, then the organism has the phenotype). http://purl.obolibrary.org/obo/RO_0003000 produces a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix. http://purl.obolibrary.org/obo/RO_0003001 produced_by a produced_by b iff some process that occurs_in b has_output a. http://purl.obolibrary.org/obo/RO_0002434 interacts with A relationship that holds between two entities in which the processes executed by the two entities are causally connected. http://purl.obolibrary.org/obo/RO_0002573 has modifier A relation that holds between an attribute or a qualifier and another attribute. http://purl.obolibrary.org/obo/bspo#parallel_to parallel to x is parallel t y iff x and y are lines or planes which when extended indefinitely do not cross. http://purl.obolibrary.org/obo/BSPO_0000096 anterior_to x anterior to y iff x is further along the antero-posterior axis than y, towards the head. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail. http://purl.obolibrary.org/obo/BSPO_0000098 dorsal to x dorsal to y iff x is further along the dorso-ventral axis than y, towards the back. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly). http://purl.obolibrary.org/obo/BSPO_0000099 posterior_to x posterior to y iff x is further along the antero-posterior axis than y, towards the body/tail. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail. http://purl.obolibrary.org/obo/BSPO_0000102 ventral to x ventral to y iff x is further along the dorso-ventral axis than y, towards the front. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly). http://purl.obolibrary.org/obo/BSPO_0000104 approximately perpendicular to Crosses at an angle that is 90 degrees, or close to 90 degrees. In any non-linear organism, the main axes are rarely perpendicular when taken through the organism as a whole. http://purl.obolibrary.org/obo/BSPO_0000107 deep_to Further away from the surface of the organism. Thus, the muscular layer is deep to the skin, but superficial to the intestines. http://purl.obolibrary.org/obo/BSPO_0000108 superficial_to Near the outer surface of the organism. Thus, skin is superficial to the muscle layer. http://purl.obolibrary.org/obo/BSPO_0015005 orthogonal to crossing at right angles http://purl.obolibrary.org/obo/BSPO_0015006 passes through Intersects at two points. http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to A mereological relationship or a topological relationship http://purl.obolibrary.org/obo/RO_0002328 functionally related to A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities. http://purl.obolibrary.org/obo/RO_0002321 ecologically related to A relationship that is mediated in some way by the environment or environmental feature (ENVO:00002297) http://purl.obolibrary.org/obo/RO_0002410 causally related to This relation groups causal relations between material entities and causal relations between processes http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c. http://purl.obolibrary.org/obo/RO_0002609 obsolete related via dependence to A relationship that holds between two entities, where the relationship holds based on the presence or absence of statistical dependence relationship. The entities may be statistical variables, or they may be other kinds of entities such as diseases, chemical entities or processes. http://purl.obolibrary.org/obo/RO_0002201 phenotype of inverse of has phenotype http://purl.obolibrary.org/obo/RO_0040035 disease relationship This relation groups relations between diseases and any other kind of entity. http://purl.obolibrary.org/obo/RO_0001018 contained in contained_in http://purl.obolibrary.org/obo/pato#correlates_with correlates_with http://purl.obolibrary.org/obo/RO_0002464 helper property (not for use in curation) http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage http://purl.obolibrary.org/obo/BSPO_0015001 finishes axis http://purl.obolibrary.org/obo/BSPO_0015007 starts axis http://purl.obolibrary.org/obo/BSPO_0015008 surface of http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/RO_0002502 depends on http://purl.obolibrary.org/obo/RO_0001019 contains